Unlocking the Next Chapter in Healthcare
by ROHIT MAHAJAN and RITU M. UBEROY
Foreword by Edward Marx
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In the rapidly evolving landscape of healthcare, the integration of artificial intelligence (AI) is not just a possibility; it is an inevitability. As we stand on the brink of a new era, the potential of AI to revolutionize medicine is both exhilarating and daunting — and necessary! “Generative AI: Unlocking the Next Chapter in Healthcare” serves as a beacon and guidebook for those navigating this transformative journey, offering insights into the profound impact of Large Language Models (LLMs) and Generative AI (GAI) tools like ChatGPT or Gemini on the medical field.
The healthcare industry is no stranger to innovation. From the discovery of antibiotics to the development of minimally invasive surgical techniques, each advancement has been a stepping stone toward better patient outcomes and improved experiences. However, the advent of AI represents a paradigm shift unlike any other. It promises not only to enhance existing practices but to redefine the very fabric of healthcare delivery and research. While some technologies of the past never lived up to their hype, AI is likely to exceed the hype as we continue to execute on its promises.
This book is Rohit Mahajan and Ritu M Uberoy’s second exploration into the intersection of AI and healthcare. Following the success of “Quantum Care: A Deep Dive into AI for Health Delivery and Research.“, they realized that healthcare practitioners required a roadmap and real-world examples from which to operate and draw inspiration. In this new volume, they delve deeper into the specific contributions of LLMs and GAI, technologies that are radically reshaping how we approach diagnostics, treatment planning, clinician experience, and patient engagement. These tools are not just augmenting human capabilities; they are expanding the boundaries of what is possible in medicine.
One of the core strengths of this book is its commitment to technical accuracy while maintaining an engaging and accessible narrative. It is designed to be a resource for a diverse audience, including physicians, healthcare administrators, technology executives, medical researchers and administrators. By providing practical advice on GAI implementation and showcasing real-world case studies, the book equips readers with the knowledge needed to make informed decisions about integrating these technologies into their practices. The book helps readers move from the sidelines to the playing field.
Rohit Mahajan is the author of Quantum Care: A Deep Dive into AI for Health Delivery and Research, a #1 Amazon bestseller that examines the transformative power of artificial intelligence in healthcare delivery and research. He is the Founder and Managing Partner at Saviance Technologies, and CEO at BigRio and Damo. He has also worked with IBM and Wipro before becoming a widely respected entrepreneur and thought leader in AI, digital transformation, and software innovation.
Rohit is the host of The Big Unlock Podcast, where he co-leads thought-provoking conversations on healthcare innovation alongside Ritu M. Uberoy. In recognition of his contributions to digital health, he was honored with the 2025 GHLF Global Impact Award for Digital Health Innovation. He is a member of Harvard Alumni Entrepreneurs, and a Charter Member of TiE Boston. He is involved with TiE Boston Angel Network, and HBS Angels.
He holds a bachelor’s degree in Electronics and Communications Engineering, is a Wharton Fellow, and a graduate of Harvard Business School. His continuing education includes advanced programs in AI and healthcare from MIT Sloan, MIT CSAIL, Harvard School of Public Health, and the Harvard Medical School’s Global Healthcare Leaders Program.
Passionate about the intersection of innovation and impact, Rohit’s work and writing are grounded in the belief that technology should enable compassionate, equitable, and accessible care. He currently resides in the United States.
Ritu M. Uberoy is a technology executive, entrepreneur, and educator with more than 25 years of experience in the software and IT industry across the U.S. and India. As the Founder of Saviance Technologies and Managing Partner at BigRio and Damo Consulting, she has delivered transformative digital solutions to clients across healthcare, life sciences, and other sectors.
Ritu is a recognized voice in the healthcare innovation ecosystem and serves as the host of The Big Unlock—a widely followed podcast that features insightful conversations with healthcare CIOs, CDOs, and other senior leaders. Through these dialogues, she explores critical trends shaping the digital health landscape, including artificial intelligence, digital front doors, and data-driven care delivery.
Ritu heads the Generative AI Center of Excellence at BigRio. She is at the forefront of helping healthcare organizations explore and implement GenAI-driven transformation. She also spearheads the DigiMTM Digital Maturity Model and Assessment at Damo Consulting, helping provider and payer organizations evaluate and accelerate their digital journeys.
A passionate advocate for applied AI education, Ritu has hosted and facilitated GenAI webinars, workshops, and in-person events with healthcare executives and innovators across Boston, Cleveland, Houston, and other major healthcare hubs. She has successfully taught GenAI concepts in both academic and executive settings, making the complex content both accessible and actionable.
Her academic credentials include a Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT), a Master’s degree in Computer Science from Santa Clara University, and participation in the Fellows Program at The Wharton School, University of Pennsylvania. She has also completed prestigious executive programs in AI for Health Care from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education.
Ritu’s forthcoming book offers a strategic roadmap for senior healthcare and pharma leaders to harness the power of generative AI—bridging the gap between promise and practice in one of the most transformative technologies of our time.

Rohit is the host of The Big Unlock Podcast, where he co-leads thought-provoking conversations on healthcare innovation alongside Ritu M. Uberoy. In recognition of his contributions to digital health, he was honored with the 2025 GHLF Global Impact Award for Digital Health Innovation. He is a member of Harvard Alumni Entrepreneurs, and a Charter Member of TiE Boston. He is involved with TiE Boston Angel Network, and HBS Angels.
He holds a bachelor’s degree in Electronics and Communications Engineering, is a Wharton Fellow, and a graduate of Harvard Business School. His continuing education includes advanced programs in AI and healthcare from MIT Sloan, MIT CSAIL, Harvard School of Public Health, and the Harvard Medical School’s Global Healthcare Leaders Program.
Passionate about the intersection of innovation and impact, Rohit’s work and writing are grounded in the belief that technology should enable compassionate, equitable, and accessible care. He currently resides in the United States.

Ritu M. Uberoy is a technology executive, entrepreneur, and educator with more than 25 years of experience in the software and IT industry across the U.S. and India. As the Founder of Saviance Technologies and Managing Partner at BigRio and Damo Consulting, she has delivered transformative digital solutions to clients across healthcare, life sciences, and other sectors.
Ritu is a recognized voice in the healthcare innovation ecosystem and serves as the host of The Big Unlock—a widely followed podcast that features insightful conversations with healthcare CIOs, CDOs, and other senior leaders. Through these dialogues, she explores critical trends shaping the digital health landscape, including artificial intelligence, digital front doors, and data-driven care delivery.
Ritu heads the Generative AI Center of Excellence at BigRio. She is at the forefront of helping healthcare organizations explore and implement GenAI-driven transformation. She also spearheads the DigiMTM Digital Maturity Model and Assessment at Damo Consulting, helping provider and payer organizations evaluate and accelerate their digital journeys.
A passionate advocate for applied AI education, Ritu has hosted and facilitated GenAI webinars, workshops, and in-person events with healthcare executives and innovators across Boston, Cleveland, Houston, and other major healthcare hubs. She has successfully taught GenAI concepts in both academic and executive settings, making the complex content both accessible and actionable.
Her academic credentials include a Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT), a Master’s degree in Computer Science from Santa Clara University, and participation in the Fellows Program at The Wharton School, University of Pennsylvania. She has also completed prestigious executive programs in AI for Health Care from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education.
Ritu’s forthcoming book offers a strategic roadmap for senior healthcare and pharma leaders to harness the power of generative AI—bridging the gap between promise and practice in one of the most transformative technologies of our time.
Introduction
Chapter 1 – Evolution of AI in Healthcare: From ML to LLMs
Chapter 2 – Current Landscape of GAI in Healthcare
Chapter 3 – Future Directions and Innovations
Chapter 4 – Key Players and Startup Opportunities
Chapter 5 – Privacy and Ethical Considerations
Chapter 6 – Challenges in GAI Implementation
Chapter 7 – Integration of GAI into Medical Practice
Chapter 8 – Impact on Healthcare Delivery
Chapter 9 – GAI in Medical Research and Drug Discovery
Chapter 10 – AI Agents Unlocking the Future of Gen AI for Healthcare
Chapter 11 – Where We Stand and Where We Dare to Go
Whether you’re exploring AI or leading transformation, this book equips you to navigate, implement, and innovate in healthcare’s next chapter.

A Deep Dive into AI for Health Delivery and Research
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