Author: Gaurav Mhetre

The Radical Transformation of Healthcare Through AI-Native Digital Platforms

The Radical Transformation of Healthcare Through AI-Native Digital Platforms

Insights by Bharat Sutariya, MD, SVP and Chief Health Officer, Oracle Health

Key Points

  • Oracle is making a bold bet that “bolt-on AI” will hit a ceiling, and that the real transformation requires rebuilding the healthcare stack with AI embedded at the foundation.
  • The next leap is moving from systems of record to systems of orchestration, where AI listens for clinical intent and queues orders, referrals, and prior authorizations.
  • Near-term value comes from reducing high-volume friction, while governance and human-in-the-loop guardrails remain essential as AI moves closer to clinical decision support.

“AI needs to do the work.”

That single line captures the urgency and ambition in this conversation with Dr. Bharat Sutariya. His core argument is not that healthcare needs more AI features. It needs a different architecture. One where AI is not bolted onto legacy workflows but embedded into the foundational layer so the system can orchestrate work across the care journey.

Dr. Sutariya’s perspective is shaped by living through every era of modern health IT. He is an emergency physician by training with 25-plus years at the intersection of healthcare and technology, including leadership roles at Detroit Medical Center, 17 years at Cerner, a stint at Deloitte, and now as Senior Vice President and Chief Health Officer at Oracle Health. He has seen healthcare move from paper to EHR documentation overload. His “origin story” into technology is simple and relatable: impatience with things that do not work, paired with a relentless drive to improve care at scale.

What makes this episode especially relevant is that it confronts the question every CIO, CMIO, and CEO is wrestling with right now: are we heading toward incremental productivity gains, or toward a fundamentally different operating model for care delivery?

Dr. Sutariya believes the answer depends on whether we keep bolting AI onto legacy systems or build platforms that treat AI as the new core of the workflow.

Listen to the full conversation

Why “Bolt-On AI” Is Only the Beginning

One of the most useful parts of this episode is the way Dr. Sutariya reframes what people blame on the EHR.

As he explained to The Big Unlock podcast host, Ritu M. Uberoy, “the EHR itself is not the only culprit. A large portion of the burden clinicians feel stems from the compounded weight of regulatory compliance, medical-legal requirements, expanded evidence requirements, and administrative demands layered onto the digital workflow over decades. The EHR became the container for all of it, so the frustration is often directed at the EHR.”

That is why he believes AI matters, but also why he believes the usual pattern of adding tools on top of legacy infrastructure will only take the industry so far.

He calls out what has become the industry norm, keeping the foundational EHR and bolt AI on top. He acknowledges that both “bolt-on” and “rebuilt” approaches can show early success, especially because the industry is still “scraping the surface” of what AI can do. But he predicts differentiation will come when AI moves from documentation and isolated agents to orchestration across workflows.

Oracle’s bet, as he told Ritu, is different. Rather than treating AI as an add-on, Oracle is rebuilding the healthcare tech ecosystem across providers, payers, and life sciences using the full Oracle stack, from database and cloud infrastructure through the AI layer to modern applications. In his words, Oracle is embedding AI into the EHR, or even more radically, embedding the EHR inside the AI.

That is not just a product story. It is a sequencing story. It says the future is not “a smarter form.” The future is a workflow engine that can interpret intent, coordinate tasks, and reduce the load clinicians carry every day.


The Shift From Documentation to Orchestration Is Already Underway

When Dr. Sutariya talks about near-term value creation, he is very specific: “reduce high-volume friction,” or the repetitive work that drives burnout. Documentation, chart review, ordering, and follow-up tasks. He argues that AI agents deployed with full chart context can meaningfully reduce burden, improve satisfaction, reduce pajama time, and improve patient interaction because clinicians are not hiding behind keyboards.

He also makes an important point about outcomes. In addition to measuring process metrics like time saved, he says Oracle is increasingly tracking clinical outcomes, financial outcomes, patient experience, and whether clinicians can operate more efficiently without sacrificing quality. That is an important evolution for the industry, because the “time saved per note” story is not enough to justify long-term platform modernization.

Then he explains what “orchestration” looks like in practice, and this is where the conversation gets concrete.

Ambient documentation is not the endpoint. It is the foundation.

As Oracle’s ambient agent listens to the clinician-patient conversation and drafts the note, it also extracts clinical intent and begins queuing actions:

  • orders mentioned by the clinician
  • prescription renewals
  • referrals to other clinicians
  • and, when appropriate, prior authorization workflows

He describes a scenario where the agent hears a clinician discuss a knee replacement. The system identifies payer requirements, retrieves prior authorization criteria, gathers relevant chart information, fills the required documentation, and presents it for clinician review or routes it to the appropriate queue for completion.

The key distinction he is drawing is that the AI is not “making medical decisions.” It is capturing clinician intent and automating downstream administrative work that normally slows care, creates delays, and drains staff capacity.

This is what he means by AI doing the work.

It is also what he means by moving from a system of record to a system of orchestration. A system that does not simply store what happened, but helps move the care journey forward.


Guardrails, Transparency, and Sequencing Are What Make This Safe

Dr. Sutariya is clear that healthcare has a different error tolerance than most industries. The “parts per million error rate” that might be acceptable elsewhere is not acceptable in patient care. Therefore, the path to AI-native orchestration cannot be reckless.

His answer combines governance, safety sequencing, and transparency.

First, he emphasizes starting with lower-risk areas, such as operational and administrative workflows. There is significant efficiency and quality improvement that can be achieved before AI moves into higher-risk clinical domains.

Second, he argues that you need trusted platforms with appropriate guardrails and governance. This is partly why he advocates moving away from a fragmented ecosystem of dozens of AI startups, each requiring data extraction and creating new cybersecurity and privacy burdens. He suggests health systems should accept that AI will be a foundational component and choose a partner or a small set of partners that can provide infrastructure, governance, and reusable services across many use cases.

Third, he describes how Oracle is thinking about transparency in assistive clinical scenarios. He gives a clear example, telling Ritu that “AI-generated chart summaries should not be opaque.” Clinicians should be able to see the source of each critical fact. He describes a workflow where clinicians can hover over a key summary element to see its source, and, with a single click, open the underlying document with the relevant text highlighted. That approach preserves clinician trust and reduces hallucination risk by making provenance visible.

This is a key theme: as AI becomes more capable, the difference between safe acceleration and unsafe automation will be traceability, explainability, and control.

Dr. Sutariya’s viewpoint is that the right platform can embed those safeguards at the infrastructure level, rather than forcing each use case to reinvent them.


The Next Chapter Is Orchestration — Not More Documentation Tools

Dr. Sutariya predicts that within a year, the conversation will move away from documentation efficiency and toward orchestration. AI should not create work. It should do work.

He also makes the North Star explicit. None of this matters unless clinicians and patients feel they get time back, are doing fewer repetitive tasks, and experience a safer path toward better care. Health systems will only win if the care delivery engine improves in a way that clinicians can sustain and patients can feel.

In his framing, AI-native orchestration is not a feature. It is the path to a connected, intelligent ecosystem where intent becomes action and administrative work no longer consumes the clinical day.


The Takeaway

Dr. Bharat Sutariya’s message is both ambitious and practical. “Bolt-on AI” can deliver early wins, but healthcare’s real transformation requires AI-native orchestration built into the foundational platform. Dr. Sutariya’s prediction is that the industry will quickly move from “documentation efficiency” conversations to “orchestration” conversations, and that winners will be the health systems and platforms that sequence safely, maintain transparency, and deliver what clinicians and patients actually want: time back, fewer repetitive tasks, and a more connected care experience.

Sitting at the intersection of emergency medicine, decades of EHR evolution, and AI-native platform strategy, Dr. Sutariya’s unique insights are especially valuable:

  • EHR “burden” is compounded by decades of compliance and administrative layering, and AI is an opportunity to unwind friction rather than add another layer.
  • Bolt-on AI will show early success, but orchestration will differentiate platforms once health systems demand end-to-end workflow impact.
  • Ambient is the beginning, not the end. The real value is when AI listens for clinician intent and automates follow-on tasks.
  • Orchestration means connecting the conversation to action: queuing orders, referrals, and prior authorization workflows while preserving human control.
  • Decision fatigue is real. Health systems should choose trusted AI partners and infrastructure rather than bolting on dozens of point solutions.
  • Transparency and provenance are essential as AI moves closer to clinical workflows, and must be designed into the platform, not patched on.

At the Intersection of AI, Healthcare, and Real-World Impact

Why We’re Heading to DHAI 2026

Healthcare transformation rarely happens in isolation. It happens when innovators, clinicians, investors, policymakers, and operators come together to ask one essential question:

How do we move from innovation to impact?

That is exactly why I’m excited that Rohit Mahajan and I will be attending the Digital Health & AI Summit (DHAI) 2026, hosted by World BI, where we’ll be covering the conversations, insights, and emerging signals for The Big Unlock Podcast.

If the past few years were about discovering AI, the next phase is clearly about deploying it responsibly and at scale.

And DHAI 2026 sits right at that inflection point.

DHAI is Bringing Together Global Healthcare Leaders

The Digital Health & AI Summit 2026 brings together global healthcare leaders, health systems, startups, pharma innovators, investors, and technology visionaries to discuss how artificial intelligence is reshaping healthcare delivery, operations, research, and patient experience.

Unlike many conferences that focus purely on technology, DHAI emphasizes something more important:

Operational reality.

The questions being asked today are no longer theoretical:

  • How do health systems deploy AI safely?
  • What does an AI-enabled workforce actually look like?
  • Can voice agents, copilots, and automation reduce clinician burden?
  • Where is real ROI emerging from AI investments?

These are the exact conversations we explore every week on The Big Unlock — and DHAI provides a live global forum where those ideas collide with real implementation stories.

From AI Pilots to AI Infrastructure

Across healthcare, we’re seeing a fundamental shift.

Healthcare organizations are moving from isolated pilots to enterprise AI platforms.

We’re witnessing:

  • AI copilots supporting clinicians
  • Voice agents transforming access and patient engagement
  • Automation redefining revenue cycle and operations
  • Predictive intelligence influencing care pathways

But success is no longer about deploying a single model.

It’s about building intelligent healthcare ecosystems.

The leaders gathering at DHAI understand that the future belongs to organizations that integrate AI across workflows — not bolt it onto existing systems.

The Big Unlock Is on a Mission

For nearly a decade, The Big Unlock has focused on one mission:

Understanding how digital innovation actually transforms healthcare organizations.

Through conversations with CEOs, CMIOs, founders, policymakers, and investors, we’ve learned an important truth:

Technology does not transform healthcare.
Leadership, strategy, and execution do.

At DHAI 2026, Rohit and I will be meeting innovators, interviewing leaders, and capturing the real stories behind AI adoption — the successes, challenges, and lessons that rarely make it into press releases.

Expect upcoming podcast episodes and insights covering:

  • AI adoption realities inside health systems
  • Startup innovation versus enterprise deployment
  • The evolving role of clinicians in an AI-augmented world
  • Global perspectives on responsible AI in healthcare


The Bigger Moment for Healthcare AI

We are entering what I believe is the second wave of digital health transformation.

The first wave digitized healthcare.
The second wave is making healthcare intelligent.

AI is no longer an emerging technology — it is becoming foundational infrastructure for care delivery.

Events like DHAI matter because they help the ecosystem align around shared priorities:

  • Better patient outcomes
  • Sustainable healthcare economics
  • Workforce resilience
  • Ethical and scalable AI adoption

And perhaps most importantly, they remind us that innovation must remain human-centered.


Join the Conversation

If you’re attending DHAI 2026, I hope you’ll connect with us.

Rohit Mahajan and I will be recording conversations, gathering perspectives, and bringing the most important insights back to the global healthcare community through The Big Unlock.

Because the real unlock in healthcare isn’t AI alone.

It’s how leaders choose to use it.

Ritu M. Uberoy
Co-Host, The Big Unlock Podcast

Rural Resilience and Balancing Clinical Care with AI Innovation

Season 7

Episode 207 - Podcast with Andrew Porter, CEO, Wayne General Hospital
Rural Resilience and Balancing Clinical Care with AI Innovation

The Big Unlock
The Big Unlock
Rural Resilience and Balancing Clinical Care with AI Innovation
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In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare delivery. Drawing on his unique “three-legged stool” perspective as a clinician, administrator, and academic, Andrew highlights the necessity of staying nimble in a rapidly evolving market.

Wayne General is taking a pragmatic approach to AI by focusing on real problems instead of technology hype. Andrew details the successful implementation of ambient AI documentation, which has improved provider satisfaction and restored the intimacy of the patient-physician relationship. He also discusses leveraging AI partnerships to bring high-sophistication care, such as heart murmur detection, to rural populations. Andrew emphasizes the critical need for AI-driven transformation in the revenue cycle to alleviate the administrative complexity burdening small hospitals. Take a listen.

About Our Guest

Andrew Porter is the Chief Executive Officer of Wayne General Hospital in Waynesboro, Mississippi where he leads strategic planning and daily operations. A graduate of the University of Lynchburg’s Doctor of Medical Science program as part of its second cohort, Dr. Porter continues to practice emergency medicine in the rural setting.

He is certified as a Physician Assistant by the NCCPA and holds the Emergency Medicine Certificate of Added Qualifications (EM-CAQ). Throughout his career, Dr. Porter has served on numerous advisory boards and boards of directors and has also provided expert testimony as a defense expert witness.

Dr. Porter has a special interest in public-private venture partnerships and has successfully structured and closed several collaborative initiatives designed to expand healthcare access and innovation in rural communities. In addition to his clinical and administrative experience, he completes his professional triad with a strong commitment to academics. From classroom teaching and precepting to research and program development, he finds preparing the next generation of healthcare professionals to be one of the most rewarding aspects of his work. He has previously served as an Associate Preclinical Director and held multiple adjunct faculty appointments.

Despite his professional accomplishments, Dr. Porter considers his family his greatest achievement and enjoys spending as much time as possible with his wife and three children on their tree farm.


Ritu: Hi everyone. Welcome to the Big Unlock Podcast. My name is Ritu Oberoi. I’m the managing partner here at Damo Consulting and co-host of the Big Unlock Podcast. A very warm welcome to all our listeners to Season Seven. Today we are very thrilled to have with us Andrew Porter. He serves as a key leader at Wayne General Hospital, where he’s driving forward initiatives focused on operational excellence, patient-centered care, and sustainable growth for a community-based health system. Andrew has been instrumental in advancing strategic priorities that strengthen access, improve outcomes, and enhance workforce resilience. Looking forward to a very in-depth and engaging conversation. Welcome, Andrew. Thank you.

Andrew: Thank you for having me.

Ritu: Would you like to add anything to that introduction, or shall we get started?

Andrew: I’m on y’all’s time. I’d just like to say it’s a privilege and an honor to get to chat with you all today, and for your listeners to get to know us here at Wayne General Hospital a little better. I’m excited about what we get to talk about today.

Ritu: We usually like to start with an origin story — asking our guests how they got into healthcare, and particularly into this intersection of healthcare, administration, and tech. If you can tell us a little about your background and how you came to this role, we’d love to hear that.

Andrew: Of course. It’s a winding path of how I ended up here, so I’ll give y’all the short elevator version. I actually started working here at Wayne General when I was still in high school — my first job was here as an ER tech. I did that through high school and into college. I initially went the clinical route in my education. I’m a PA by trade and practiced emergency medicine — I continue to do that to an extent even now. I did some teaching and education along the way, earned my doctorate in medical sciences with a focus on healthcare administration, and then the opportunity came along to return to my hometown to practice emergency medicine. I was able to bring that education and administrative leadership skill set with me, and the rest is history. My board of trustees put faith in me to be the CEO here at the hospital, and here we are today.

Ritu: Thank you for sharing that. You have this professional triad of clinical experience, administrative experience, and a strong commitment to academics. Which part is your personal favorite?

Andrew: I had an accounting professor once who described it beautifully using the analogy of a three-legged stool. Professionally, I have a clinical component, an academic component, and an administrative component — and for me personally, each one of those legs makes the other stronger. Continuing to work on the front lines in healthcare gives me a much better sense of the needs of the community and the pulse of my staff. There are so many times that being in the emergency department, interacting with staff at that level, allows me to catch something that could turn into a significant cultural or logistical issue before it becomes a larger problem. The adjunct teaching keeps me sharp on what the research is showing and where best practices are headed in five to ten years. Having that academic hat on makes me a better administrator. I know the practical challenges, but I also bring the academic perspective to the table. Together, all of that helps me drive our system using best practices, while keeping today’s financial challenges in mind, maintaining a strong strategic plan, and staying nimble — because the healthcare world today is essentially completely different from what it was a year ago.

Ritu: I like that analogy — it really helps visualize exactly what you’re saying, that you have to keep all three things in balance and each one makes the others stronger. Thank you for sharing that. Andrew, I wanted to hear more about Wayne General, because you operate in this challenging community hospital environment. What specific operational or financial levers have had the biggest impact in maintaining both quality and sustainability? We’ve been hearing from other health system C-suite leaders that it’s always a resource crunch and you’re constantly having to do more with less. Beyond AI, what’s top of mind and how do you face those challenges?

Andrew: A little more detail about our organization: we are the sole community hospital for our area, serving a population in excess of 50,000 people given our rural geography and how far our reach extends. We’re county-owned — which may be unique to some listeners — meaning we are actually a political subdivision of Wayne County. Even though we don’t receive any taxpayer funding, we have been financially sustainable for many, many years. At the end of the day, the reality is that we really try to embrace the idea that we’re the people’s hospital. We are owned by the people of Wayne County. We have the nonprofit designation, and I describe it to people this way: 365 days a year, our goal is high-quality patient care. We’re not a for-profit organization answering to shareholders — we answer to the people. But to meet those needs, you have to have money, so at the end of the day it’s still a business. It’s a unique business model, but you still have to get cash in the door. For small hospitals like ours, there’s been so much transition since COVID. We went through an EHR transition during that period, which is always a very big undertaking for a smaller health system. Navigating how that intertwines with the revenue cycle has been a big challenge. For a small community hospital leader, the name of the game right now is being conservative with finances, valuing our independence, and keeping the financial side right up there with patient care — because to offer a high level of patient care, we have to be in a good financial situation.

Ritu: Absolutely. Taking that further — where do you see the most practical near-term opportunities for AI and automation? How far along are you on that journey? We hear a lot about ambient documentation, voice agents, and digital front door technologies, since clinicians are still cautious about AI for diagnostics and clinical decision-making. Where is Wayne General with those technologies?

Andrew: About a year ago, I very distinctly remember having conversations of the nature of: we don’t want to get left behind. So we took a hard look at where our pain points were — but we weren’t going to go out and try to fix problems with AI that didn’t exist. We said: let’s look at the issues we’re actually having and see if AI might be part of the solution. A good example is the ambient documentation and AI-assisted documentation space — that was one of the first areas we went down that path, and it’s been very positive for us. We’ve had it active in a substantial way for about two months now, so it’s still a little early to have a complete picture of the financial implications around improved documentation. I will tell you, the timeliness of documentation has absolutely improved. But for me, the biggest factor has been provider satisfaction. Even some of our later-career providers — who are sometimes resistant to new technology — have tremendously embraced the use of AI for documentation assistance. I would argue that has added longevity to certain providers, and while I don’t yet have a way to quantify this, I believe it’s also improving the patient experience. Instead of the provider feeling rushed to get back to the keyboard and complete documentation, medicine now becomes more what it was intended to be — an intimate, conversational interaction between the patient and their physician or provider focused on the patient’s needs that day.

Andrew: So AI-assisted documentation is what comes to mind first as something we’ve implemented and are seeing really positive early results from.

Ritu: I was having a conversation a few months ago with one of our C-suite guests, and they mentioned that one important benefit of ambient documentation is that doctors are vocalizing more — and that’s great for patients because they love to hear more. Because the system is capturing everything in the background, providers are actually saying things out loud that they might otherwise have just thought, and that really helps.

Andrew: That’s a great point, and putting my clinician hat on — it’s so easy to see a patient and say something like, “I think you have pneumonia, we’re going to run a couple of tests and get a chest X-ray,” and then move on. With ambient documentation, you’re naturally encouraged to be more detailed in that conversation because you know it’s going to be populated into the note. The conversation becomes: “Here’s my concern about what we may be dealing with. I’m going to order X, Y, and Z tests. Here’s what I’m looking for. This is the initial treatment plan.” And the way I have my AI-assisted documentation tool set up, every time I go into the room it timestamps it — which is an additional encouragement to make sure that every 30 minutes, every hour, or whatever is appropriate, I’m reassessing the patient and providing updates to them. So while it may not have been the original intent, it also increases accountability — making sure you’re having those detailed, appropriate conversations with the patient and their family and checking in on them regularly. Personally, those have been some of the real positives for me.

Ritu: Going along those same lines, you mentioned some of those physicians were from an older generation and more resistant to technology. Let’s talk about change fatigue and the barriers to digital transformation. How did you break down those barriers and get everyone on board?

Andrew: For us, one of our more experienced clinicians had actually heard that this technology was becoming available. We let him do a little research, look at different vendors, and participate in the selection process — and then we let him be the first user for a couple of months. He really became our champion. The sell was easy after that because when this particular person — someone who hates technology and wishes we could still do everything on paper — starts telling his colleagues, “This is as close to charting on paper as we’re probably ever going to come again. It’s decreased my workload. I’m not staying hours after my shift or coming in on my days off” — that carries a lot of weight. So for other organizations, finding that champion early on and giving them real buy-in to the project was really key for us.

Ritu: Basically, have the change driver be someone who has a personal stake in the change and can genuinely influence others around them.

Andrew: And realizing that the right agent of change may not be the first person who comes to mind. It doesn’t need to be the newest graduate clinician. It probably needs to be someone more senior, because your senior medical staff will have those long-standing relationships with colleagues, and the trust they carry operates on a different level.

Ritu: Looking ahead, what do you believe will differentiate the community hospitals that thrive from the ones that struggle to survive? Resources are always going to be scarce. What are the key factors that will keep Wayne General — and community hospitals in general — on the path to sustainability?

Andrew: We have a saying in medicine: you often don’t want to be the first to do something, and you don’t want to be the last. For us, that meant while we may not be the very first to try something, we do want to stay on the cutting edge. If we see a product or solution that has worked for others and makes sense for us, we’re going to consider going down that path. The AI vendor market has opened up so many opportunities for relationships and solutions. One thing we’ve been very fortunate with is our relationship with Eko Health, who make the Eko stethoscope. We’ve partnered with them on various research projects using their Sensora AI tool for heart murmur detection, and that’s been a great relationship. That gets into the space of how we use AI to increase access to care — bringing a level of technology and sophistication to a population that historically would have been years behind what could be offered in a large metropolitan area. We’re passionate about bringing that cutting edge of care when it makes financial sense and when we have the capabilities to support it. We’re proud of that relationship and look forward to the research that will come out of that partnership.

Ritu: As you’ve explored AI on your own — and you mentioned you’re always doing research — what do you feel are some of your personal favorite areas you’d like to know more about? And where do you think the biggest change in healthcare is headed in the next year or so? Crystal ball?

Andrew: Putting my administrator hat on — something is going to have to change in the revenue cycle space: coding, billing. There has to be some relief at some point for our hospitals, because the current model is enormously complex. I’ll be very honest — I by no means fully understand the revenue cycle, let alone a layperson trying to make sense of it. And just the timing alone — how long it takes from when a patient is seen to when the facility receives payment — you’re often looking at 30 to 60 days at minimum. I really hope that health systems and payers can come together and find solutions with AI in coding, billing, and that whole arena. That would be huge for everyone. So while it may not be a crystal ball prediction with a definitive endpoint, that’s Andrew’s hope for what will happen.

Ritu: That’s a tough one because it involves so many players and everything is so fragmented. To build something that can communicate across all of them — that’s the barrier we’ve been hearing about from everyone. Everything is so siloed. Unless there are protocols that allow components to talk to each other — maybe with agents from each side communicating and speeding up the process — maybe that’s the future.

Andrew: That would be incredible.

Ritu: Maybe that is the future. It’s been a great conversation. Thank you so much for joining us on the Big Unlock Podcast. It’s been a pleasure having you as our guest. Thank you so much, Andrew.

Andrew: Thank you. It’s been an honor.

About the Host

Ritu M. Uberoy is a healthcare AI strategist, technology executive, educator, and author dedicated to advancing the responsible adoption of Artificial Intelligence across healthcare delivery, digital health, and life sciences. With more than twenty-five years of leadership experience spanning the United States and India, she is recognized for helping healthcare organizations move beyond experimentation to achieve scalable clinical, operational, and business transformation through AI.

She leads AI innovation initiatives, including the AI Center of Excellence at BigRio, where she works with health systems, healthcare technology companies, and life sciences organizations to operationalize Generative and Agentic AI solutions responsibly. Her work focuses on aligning AI innovation with clinical workflows, governance frameworks, workforce readiness, and patient trust—ensuring technology augments human judgment in high-consequence healthcare environments.

Ritu is the co-author of Generative AI: Unlocking the Next Chapter in Healthcare, a practical guide for healthcare executives navigating enterprise AI adoption. She also hosts The Big Unlock podcast, engaging global healthcare leaders on AI transformation and digital innovation. An active educator and speaker, she conducts executive workshops and participates in global forums like HIMSS, ViVE, Women in Tech, AI-Powered Women, RAISE, and more, shaping the future of AI-driven healthcare. Ritu holds advanced degrees in Computer Science and completed specialized AI programs at Harvard and MIT.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Doing More With Less: How Rural Health Systems Can Drive Tech Innovation Even With Significant Resource Constraints

Insights by Linda Stevenson, Chief Operations & Information Officer, Fisher-Titus Health

Key Points

  • Rural health innovation is an execution discipline: partnerships, workflow optimization, and outcome focus matter more than shiny tools.
  • AI is “just another tool” within a larger strategy, and leaders should start with the problem before deciding whether AI fits.
  • Interoperability and cybersecurity remain the biggest constraints in rural areas, and rural vulnerabilities weaken the entire healthcare chain.

“We’re a hundred-bed rural hospital, so we do more with less.”

That’s the context Linda Stevenson brings to this episode, and it changes the entire tone of the conversation. Fisher-Titus Health is a community-based system in Norwalk, Ohio that spans care across the full patient lifecycle, from birth to end-of-life care, including physician practices, home health, skilled nursing, and nursing home services. And as of March, Stevenson’s role expanded beyond CIO responsibilities to include COO oversight of ancillary services, facilities, and environmental services.

Her story is also a reminder that healthcare technology leadership doesn’t require a linear path. She started typing bills on a typewriter, moved into analyst work because she was always asking “why,” then progressed through project management, security, and major EHR implementations, including an early Epic rollout at Cleveland Clinic and vendor-side experience at Cerner (now Oracle Health). Her advice is simple. Say yes, even when you’re unsure. That “jump in the pool” mindset is also how she took on the COO role.

But the most important part of this episode is not her resume. It’s her operating philosophy for rural health systems: stay grounded in enterprise strategy, focus on real outcomes, and resist the temptation to treat AI as a standalone strategy.

Listen to the full conversation

Rural innovation is partnership plus pragmatism, not a single priority

When asked what a CIO should prioritize today, Linda answers with the only honest response, “all of it.”

Innovation, cost control, operational reliability, productivity, clinician experience, and patient access all compete for attention. And in a rural system with constrained budgets and staffing shortages, those trade-offs quickly become real issues.

Her way of navigating that complexity is partnership.

She repeatedly returns to the need to partner with nursing leaders, finance leaders, operations leaders, and clinical stakeholders to identify the real constraints and the real opportunities. In some areas, the problem is recruitment. She points to therapy departments that cannot find enough therapists. The strategy isn’t to cut staff. It’s to use technology to help the available staff work faster without sacrificing quality, so more patients can be seen.

In other areas, the problem is cost. Linda points toward application rationalization and optimization, using what you already pay for more effectively, consolidating where you can, and getting the best value for each dollar spent.

And sometimes the ROI is human. She highlights automation and workflow improvements not only for productivity but also to reduce daily stress and burnout for staff and to improve patient access.

The underlying point is a rural reality: you don’t get to pursue innovation as a separate track. Everything has to map back to outcomes. Everything has to be anchored in what the organization can operationalize with limited people and limited dollars.


“I don’t have an AI strategy. I have a strategy”

Linda has been in healthcare long enough to see buzzwords come and go. She remembers cloud hype, early EHR hype, and other “next big things” that were positioned as the answer to everything.

That’s why her framing of AI is so grounded.

When people started asking about “AI strategy” two years ago, her reaction was simple. AI is another tool. It might be more impactful than some past shifts, but it still needs to align with the organization’s enterprise and technology strategies.

Her overarching philosophy is one rural health leaders will recognize immediately: “the goal is not to chase shiny objects. The goal is to solve problems.”

This is why her adoption model starts with a practical sequence:

  • Partner with leaders in each area to identify the problem.
  • Define the outcome you want, i.e.: productivity, cost savings, time savings, quality improvements, or patient satisfaction.
  • Then determine whether AI is the right tool, or whether another approach solves the problem better.

She also addresses what keeps teams aligned, “explaining the why.”

Many vendors will pitch a shiny solution, and some of those will become strong partners. But not all. Linda emphasizes that leaders need to understand why certain products fit and others don’t, especially because rural systems don’t want 30 different tools solving a single category of problems.

Once stakeholders understand the reasoning, they’re often open to pursuing an integrated path rather than chasing every new option.

This is also where her perspective is quietly strategic: she’s not anti-AI. She’s anti-randomness. She wants AI used where it improves outcomes and operations, not where it creates more complexity.


Interoperability and cybersecurity are rural health’s biggest constraints

Few topics reveal the rural challenge more clearly than interoperability.

Linda notes that interoperability has been discussed for years, but even when systems are technically “connected,” the information does not always flow in a way clinicians can use. That’s the real gap. Not whether data can move, but whether it arrives in a usable, workflow-friendly format.

This problem is amplified in rural settings because rural hospitals rarely have a closed ecosystem of specialists. They refer out. They coordinate across organizations. They need continuity of care across walls.

She gives a vivid example, explaining to host Ritu M. Uberoy, how maternity records still don’t flow cleanly through standard interoperability formats. In some cases, systems still fax papers back and forth with outside OB physicians. That reality undercuts the “interoperability solved” narrative and reinforces how much work remains in real-world care coordination.

She also points to a pathway rural leaders can use to influence improvement and engagement at the state level. Linda serves on the board of Ohio’s HIE and praises the state’s progress, not only for CCDAs but for broader population health initiatives and Medicaid support. Her argument is that rural systems cannot solve interoperability alone. They need collective coordination through state infrastructure and policy.

Cybersecurity is the other constraint she highlights, and her perspective comes with unusual credibility. She testified at the Senate HELP Committee on rural healthcare and cybersecurity risk. Her message is straightforward: rural systems have smaller budgets, smaller teams, and fewer cybersecurity professionals available to recruit. That makes it harder to keep up with constant attacks and harder to manage third-party risk.

But her most important point is structural: rural systems are links in a chain. Many organizations connect through them, directly or indirectly. If a rural link is weak, the broader healthcare chain is weak.

That framing should matter to every leader, not only rural CIOs. Cyber resilience is not isolated. It is ecosystem-level.


Take a breath, stay strategy-driven, and don’t buy a million shiny objects

Linda closes with advice that feels especially relevant right now. AI is moving fast. Costs are changing. Vendor promises are everywhere. The pace can create pressure to rush, to buy, to “do something” just to keep up.

Her guidance is to take a deep breath.

Think it through. Stick to strategy. Don’t rush into a million shiny objects. Focus on where technology truly benefits outcomes. And don’t forget the human dimension, including your own well-being. When leaders run at this pace nonstop, health systems lose clarity and teams burn out.

Her message is a “rural health reality check” with broader relevance. To Linda, the organizations that win won’t be the ones that adopt the most tools. They’ll be the ones that align technology to enterprise priorities, build partnerships that scale, and strengthen interoperability and cybersecurity so care can extend beyond walls without breaking.


The Takeaway

Linda Stevenson’s message is refreshingly grounded. Rural health systems don’t need an “AI strategy,” they need a strategy, with AI used only when it clearly advances outcomes. In a 100-bed hospital with a lean IT team, innovation is less about building new tools and more about partnership, workflow optimization, and disciplined choices that reduce complexity instead of expanding it. The leaders who succeed in this environment will be the ones who stay “strategy-driven,” resist shiny object overload, and build trusted partnerships that help them do more with less while still delivering the quality and continuity their communities depend on.

Sitting at the intersection of rural operations, enterprise technology leadership, and ecosystem-level cybersecurity advocacy, Linda Stevenson’s unique insights are especially valuable:

  • Rural innovation requires practical partnership across leaders to improve outcomes with limited resources.
  • Start with the problem, then decide if AI fits; AI is a tool, not a standalone strategy.
  • Workforce shortages make productivity tooling essential, not optional, especially in therapy and clinical support areas.
  • Interoperability still fails in real workflows, and rural care coordination magnifies the pain of gaps.
  • Rural cyber vulnerabilities weaken the entire healthcare chain, making resilience an ecosystem issue.
  • The best advice in a high-velocity market is to stay disciplined: take a breath, stay aligned with strategy, and avoid shiny-object overload.

Can AI Make Healthcare Feel More Human and the Case for Why it Should

Insights by Ed Lee, MD, MPH, Chief Medical Officer, Nabla

Key Points

  • Ambient AI’s deepest ROI is not minutes saved. It’s reducing cognitive burden and restoring presence in the exam room.
  • Change management, not model quality, is the make-or-break factor in AI adoption.

“At the end of the day, AI is just technology. If we do this right, it shouldn’t feel technical. It should feel more human.”

Dr. Ed Lee’s thought is simple, but it’s also a standard that healthcare leaders can actually use. It reframes the discussion away from model capability and toward lived experience. What do clinicians and patients feel when AI shows up in the room?

Dr. Lee’s perspective comes from spending years in one of the most operationally disciplined care-delivery environments in the country. He grew as a practicing clinician at Kaiser Permanente, where integrated payer-provider delivery forced every workflow change to meet a high bar. Technology could not be adopted simply because it was new. It had to help clinicians focus on patients and reduce the friction that screens and administrative tasks introduced between people and care.

Today, as Chief Medical Officer at Nabla, Dr. Lee is applying those lessons to ambient AI and clinical copilots. He’s explicit that the end goal is not efficiency alone. It’s restoring joy in medicine, reducing cognitive burden, and rebuilding the patient-physician relationship. In his view, that’s where the real ROI lives.

Listen to the full conversation

The hardest part of AI adoption isn’t the AI

When asked about what he learned at Kaiser Permanente, Dr. Lee doesn’t start with feature sets or architecture. He starts with human interaction and clinicians’ ability to focus.

He describes how easily technology can unintentionally get in the way of personalized care, and how the right tools should remove friction rather than add it. But when the conversation shifts to adoption, his answer becomes even more direct: “The hard part is not the technology. It’s change management.”

Dr. Lee puts it plainly to our host, explaining that change management is often the hardest part of implementing new technologies. Clinicians are scientific and evidence-driven. They want to understand “the why.” They want proof that a new workflow will improve care, not simply create another layer of tasks.

That’s why he argues clinician involvement from day one is non-negotiable. If clinicians aren’t brought in from the beginning, he believes teams are “often destined to fail.” This isn’t a philosophical point. It’s an implementation reality. Even the best tool will stall if it’s introduced as something imposed on clinicians rather than built with them.

He also addresses a familiar tension in the current AI narrative. Yes, AI can perform well on standardized tests and sometimes generate outputs that look smarter than what humans could write quickly. But he insists the appropriate framing remains augmentation, not replacement. The clinician must integrate information into the clinical context and remain responsible for the decision.

In practice, Dr. Lee’s message is a reminder that the adoption playbook is not about persuading people that AI is amazing. It’s about building trust through evidence, involvement, and workflow fit.


Ambient AI’s ROI is cognitive relief and restored agency, not a stopwatch metric

The early story of ambient AI was mostly about time savings. And Dr. Lee acknowledges that’s how many organizations first evaluated it: minutes per encounter, hours per day, pajama time reduced.

But he points out something important. The data has evolved, and the experience varies. Some clinicians do save substantial time. Others save less per encounter than the early narrative suggested. Some still have after-hours work even with ambient tools.

And then he pivots to what he sees as the deeper value: agency.

Dr. Lee explains that ambient tools can help clinicians budget their time as they choose. A clinician could compress the day and finish earlier. Or they could invest the recovered capacity back into their patients, slowing down to develop relationships, think more carefully, and communicate more clearly. The key is that the clinician regains control over the time and attention economy of the clinical day.

From there, he connects ROI to something bigger than time: cognitive load, cognitive burden, and meaning.

He argues that the real gain is that clinicians can do what they went into medicine to do. Not to be a transcriptionist. Not to be glued to a computer. But to be a caregiver and scientist who applies evidence to improve lives.

That’s where he believes ambient AI becomes strategic. Burnout reduction and retention aren’t abstract. They are operational outcomes. The tool may not eliminate every after-hours minute, but if it restores attention and reduces mental strain, it can improve the clinician experience in a way that matters in the long term.

Dr. Lee also highlights an unexpected “win-win” effect: ambient AI can improve the patient experience. As clinicians verbalize more to ensure the technology captures the right context, patients often feel more engaged. They hear more explanations. They experience a more meaningful interaction. What began as a documentation tool can become a relationship tool, almost as a byproduct of how clinicians use it.

That’s a key point for leaders evaluating ROI. If you only measure time saved, you might miss the bigger transformation: better communication, stronger trust, and improved clinician-patient connection.


The next frontier is workflow-native intelligence

For Dr. Lee, ambient documentation is only the first layer.

He describes the next phase already arriving. It includes diagnosis capture, coding support, surfacing the right ICD-10 and CPT codes, and improved documentation to support the financial integrity of care delivery. He’s clear that accurate documentation can improve how organizations capture what they are doing and justify it appropriately.

But he also points beyond the financial layer into clinical workflow intelligence:

  • chart summarization that distills decades of patient history into what matters now
  • surfacing key context at the point of care
  • clinical decision support that suggests diagnoses, diagnostic tests, and treatment options
  • orders that can be staged on behalf of clinicians, as long as the trust layer is strong

He notes that adoption of decision support will depend on trust, which takes time to build. But he believes clinicians will be enthusiastic if the tool supports their workflow without adding noise.

This is also where his “friction” framing returns. It’s not just what the tool can do. It’s how it does it.

If a tool adds five extra clicks per patient, clinicians won’t use it. Usability and integration matter as much as capability. Dr. Lee emphasizes that “hope is not a strategy.” You can’t release tools and assume adoption happens. Adoption must be engineered through workflow understanding, usability design, and deliberate change management.

In his best-case vision, AI becomes invisible infrastructure. It fades into the workflow. It reduces friction and supports clinicians through the entire loop: intake, documentation, orders, summarization, and decision support.


Done right, AI shouldn’t feel technical. It should feel human.

Dr. Lee’s message is consistent across the episode. The goal of AI in healthcare is not to make clinicians type faster. It’s to help clinicians be more present with patients, to reduce administrative burdens, and to restore the human side of care.

He doesn’t deny the importance of ROI. He simply reframes it. The deeper ROI of ambient AI extends beyond minutes saved. It’s cognitive relief, restored agency, reduced burnout, better recruitment and retention, and more meaningful patient interactions.

And he grounds the future in execution reality. The next wave will bring decision support, diagnosis capture, and chart summarization deeper into workflows, but only if organizations do the hard work of clinician involvement and change management. Technology alone won’t carry adoption. Trust and usability will.


The Takeaway

Dr. Ed Lee’s view of healthcare AI is refreshingly grounded: the goal isn’t efficiency for its own sake, it’s restoring human connection in care. Ambient AI is the first major proof point because it reduces cognitive burden, gives clinicians agency over their time, and can improve the quality of clinician-patient communication as a natural byproduct. But Dr. Lee is clear that the hardest part isn’t the tool, it’s adoption: change management, workflow fit, and clinician involvement from day one. As ambient evolves into chart summarization, diagnosis capture, and decision support embedded directly into the clinical workflow, the standard should stay the same. Done right, AI shouldn’t feel technical. It should feel human.

Sitting at the intersection of integrated care delivery experience and real-world ambient AI deployment, Dr. Lee’s unique insights are especially valuable:

  • Change management is the hardest part of AI adoption, and clinician involvement from day one is non-negotiable.
  • AI outputs can be convincing, which makes clinician expertise and context essential to prevent subtle outsourcing of judgment.
  • Ambient’s deepest ROI is cognitive relief and restored agency, not just time savings per encounter.
  • The patient experience can improve as clinicians explain more in real time, making conversations more engaging and meaningful.
  • The next frontier is workflow-native intelligence: diagnosis capture, coding support, chart summarization, and decision support at the point of care.
  • Adoption depends on frictionless integration: if it adds clicks, it won’t scale, regardless of how “smart” it is.

Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms

Season 7

Episode 206 - Podcast with Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health
Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms

The Big Unlock
The Big Unlock
Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms
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In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare through AI-native digital platforms. As an emergency physician with over 25 years of experience, including leadership roles at Cerner and Deloitte, Dr. Sutariya provides a unique perspective on moving past the “burden” of legacy EHR systems.

The core of the conversation centers on Oracle’s bold bet: moving away from the industry-standard “bolt-on” AI approach. Instead, Oracle is rebuilding the healthcare stack from the ground up, embedding AI into the foundational layer. Dr. Sutariya argues that the future of healthcare technology isn’t just about capturing data but about systems of orchestration. This means AI that doesn’t just transcribe a note but listens to the clinical intent to automatically queue orders, handle referrals, and initiate prior authorizations.

Dr. Sutariya predicts that within a year, the conversation will shift from documentation efficiency to a truly connected, intelligent ecosystem that gives time back to both providers and patients. Take a listen.

This guest appearance was facilitated through conversations initiated at HIMSS.

About Our Guest

Dr. Bharat Sutariya serves as Senior Vice President and Chief Health Officer on the executive leadership team of Oracle Health & Life Sciences, where he leads enterprise strategy, customer engagement, product advisement, and industry representation for the global business. A seasoned and forward thinking healthcare leader, he is committed to advancing the use of AI and digital technologies to modernize healthcare delivery, elevate clinical and operational performance, and improve the experience of every stakeholder across the ecosystem.

Dr. Sutariya guides customer leadership collaboratives that bring together senior clinical, operational, and business executives, ensuring their insights directly shape Oracle’s next generation intelligent health platform and the connected data ecosystem that bridges research and care. In this work, he aligns market needs with product innovation across provider, payer, and life sciences domains to support a rapidly transforming industry.

His career spans extensive leadership in healthcare technology, clinical operations, and large scale transformation. Prior to Oracle, he was a leader in Deloitte’s Integrated Health practice, driving technology enabled clinical and operational modernization for health systems nationwide. Previously, as Vice President and Chief Medical Officer at Cerner, he played a central role in developing core EHR capabilities, value based care solutions, and data driven performance improvement programs.

Board certified in Emergency Medicine, Dr. Sutariya has practiced in Michigan and Kansas. He began his career at the Detroit Medical Center, where he led major clinical transformation and health IT initiatives across the integrated delivery network, and served as a clinical assistant professor at Wayne State University School of Medicine. He completed his Emergency Medicine residency at Wayne State University and the Detroit Medical Center.


Ritu: Hi everyone. A very warm welcome to all our listeners to the Big Unlock Podcast, Season Seven. Today we are very happy to have with us Dr. Bharat Sutariya, who leads Oracle Health’s clinical AI strategy. My name is Ritu, and I am the managing partner at Damo Consulting and co-host of the Big Unlock Podcast along with Rohit. Today Rohit is not here, so I’ll be in conversation with Dr. Sutariya. Dr. Sutariya is a senior healthcare leader at Oracle Health, shaping the next generation of digital platforms and how data and AI are transforming care delivery at scale. At Oracle Health, Dr. Sutariya is focused on enabling a more connected, intelligent healthcare ecosystem, and his work sits at the intersection of platform modernization, interoperability, and the emerging role of AI in re-imagining healthcare delivery. With that, I’ll hand it over to Dr. Sutariya. Welcome to the podcast. Thank you for being our guest today.

Bharat: It’s a pleasure, and thank you for the warm welcome. I look forward to our conversation.

Ritu: Thank you so much. If you’d like to add anything beyond the introduction, we’d love to hear.

Bharat: Sure. I’ve been fortunate to be at the intersection of healthcare and technology for over 25 years. I’m an emergency physician by training and practiced for 26 years — initially in Detroit, where I trained at the Detroit Medical Center and led much of the digital transformation there. Then I moved to Cerner for 17 years, did a short stint with Deloitte, and joined Seema’s executive leadership team at Oracle Health a couple of years ago. I’ve had the opportunity to witness healthcare’s journey from paper-based practice, through read-only systems, to heavy EHR documentation, and now — what I would say is the most exciting era — where we are on the verge of delivering the vision we’ve always had: allowing clinicians to practice better, patients to generate better outcomes, and the healthcare ecosystem to reach a more sustainable path. I am more bullish and excited than ever.

Ritu: Thank you, Dr. Sutariya. We always love to start with an origin story, and doctors’ origin stories are really fascinating. We always ask: what led you to tech? Being a doctor is such a full-time job — how do you manage to combine your interest in technology and medicine? Tell us a little more about that.

Bharat: What led me to tech is a relentless focus and impatience to improve healthcare — all the way back to residency, when I simply would not tolerate the green-screen CRT machines delivering lab reports, the printers not working, things just not functioning. I’ve always had very little patience for things that don’t work, and I believe patients and providers deserve better. I’ve always looked at technology as the most scalable answer to that problem. That’s what got me into technology from the early days of residency, then leading tech transformation at Detroit Medical Center, and onward from there.

Ritu: Tell us a little more about your time at Cerner, because you had a front-row seat to both the promises and limitations of large-scale EHR systems. They were supposed to make things better, but interoperability — which was always promised — was never fully there. What lessons do you bring to Oracle Health, and how do you think you can improve on that?

Bharat: I had the pleasure of working with Neal Patterson, Cerner’s founder, for nearly 15 of my 17 years there. He always stated that healthcare is too important to stay the same — meaning it needed to evolve, and faster. That was always the focus at Cerner. Cerner started as a lab company, grew into an inpatient EHR, and then into an enterprise EHR over the years. What most people don’t appreciate is this: if we had taken the way people practiced on paper 20 to 25 years ago and simply made it electronic, EHRs would actually be quite efficient. But what we don’t often talk about is 20 to 25 years of regulatory compliance, new evidence in medicine, and the overburdening of data — all of these movements stacked on top of EHRs, combined with EHRs becoming increasingly administrative. That is what led to the burden people talk about. It’s not the EHR alone. Take E&M coding, for example — it’s quite burdensome, and many times clinicians perceive that burden as coming from the EHR, when in reality it’s the E&M coding system, the medico-legal documentation requirements, or some other external task. All of it gets compounded into an EHR issue. That’s why I’m excited about the future, because I think we have much better answers going forward.

Ritu: Thank you for that insightful answer. Oracle Health is now representing a shift toward a more unified, platform-centric model. What fundamentally changes when healthcare moves from fragmented systems to a single data and workflow layer? And what do you think will get harder before it gets easier?

Bharat: There has been quite rapid adoption of AI and modern technology over the last couple of years in particular, and we made a different bet than most of the industry. The industry largely took a bolt-on approach — keep the legacy foundational EHR and bolt AI on top of it. That’s the industry norm. At Oracle, we took a different approach: AI is too important and transformative a tool to treat that way. In addition, we had the opportunity — because of Oracle’s full stack — to leverage everything from the foundational database and Oracle Cloud OCI infrastructure, through the AI layer, to the modern application layer. So we decided to reconstruct not just the EHR, but the entire healthcare tech ecosystem across provider, payer, and life sciences, to achieve a connected ecosystem vision. For us, AI is embedded into the EHR — or you could say the EHR is embedded inside the AI. There is no bolt-on. While that requires significant resources to build what the market has had for three or four decades of legacy EHR, we’re taking the bigger bet to transform the whole thing. That does require investment, but it gives us a significant advantage to innovate without legacy constraints. The industry’s bolt-on approach is having early success, as is ours, because we are still scratching the surface of what AI can bring to medicine. Where you will see differentiation going forward: we’ve already deployed AI agents on top of our legacy Millennium EHR, but we’ve just released a brand new Oracle Health ambulatory primary care EHR that is AI-embedded, cloud-first, and truly native. It looks and behaves radically different — with far fewer menus and clicks, because AI is always present as your companion with a human in the loop. The biggest movement for us is transitioning from a system of record — which is what most EHRs have been — to a true system of orchestration and workflow. That is the transformation we are leading toward.

Ritu: I totally agree. The bolt-on approach can only lead to incremental change. If you’re looking for transformational change, you have to build with AI first in mind. That’s something we’ve talked about in our voice agent webinars — companies expect more from AI but don’t see that transformation because they’re using it as a bolt-on solution, which only delivers that incremental 10 to 20% productivity gain. AI can let you do things fundamentally differently. So what are your thoughts on invisible AI versus clinician-facing tools? We’re hearing a lot about ambient and how doctors feel free to just talk directly to the patient without the documentation burden in between. Where is the real value creation happening today?

Bharat: The biggest near-term value is in reducing what I would call high-volume friction — the tasks that typically cause clinician burnout: documentation, chart review, ordering, and all the follow-up tasks. What we’ve now demonstrated with Oracle Health’s clinical AI agents, each built for these specific purposes, is that when you deploy them with access to the full chart context, you do significantly reduce that burden. We’ve seen it in time saved, clinician satisfaction, a reduction in pajama time, and even better patient interactions — because clinicians now have more face-to-face time rather than hiding behind a keyboard. And for us, outcomes aren’t only about process measures like time saved. We’re also tracking truly clinical and financial outcomes: did patient care improve? Was the provider able to see more patients efficiently? Was the patient happier with the interaction? Those things that really matter are where we’re now transitioning. Even in these early days, focusing on high-volume friction, AI has already been tremendously helpful.

Ritu: Would you say ambient has been one of the most successful use cases of AI so far? And where do you see it going further?

Bharat: Absolutely. Ambient as an assistive technology in healthcare delivery is probably the single best technology I’ve seen in my 25-plus-year career in terms of rapid adoption — and not just rapid adoption by one or two physician groups, but across the board. Every physician group you give access to embraces it, and they use it with a high degree of sustained adoption. That’s because it adds real value. It captures documentation fairly accurately and keeps the human in the loop — the draft is presented to the clinician, who validates it before committing it to the chart. But while many startups in the industry consider that the endpoint, at Oracle Health we view it as the beginning and the foundation. For example, our ambient agent, while creating the note draft and listening to the conversation between provider and patient, is constantly monitoring that conversation. Did the physician say something about orders? “Mrs. Jones, I’m going to order X, Y, Z lab tests for you. I’m going to renew your prescription.” The agent extracts the clinician’s intent and queues up orders, prescription refills, and follow-up tasks — including referrals and prior authorizations. If Mrs. Jones needs a knee replacement, the agent understands in that moment who the payer is, whether prior authorization is required based on eligibility and coverage criteria, and if so, it retrieves the authorization criteria, pulls all the relevant information from the chart, fills it automatically, and presents it to the clinician for review. If more work is needed, it goes to the queue. The ambient conversation is directly connected to the automation of a significant downstream task, done more accurately. That’s our journey — millions of agents spinning off in the background based on that ambient conversation, continuing the care journey forward.

Ritu: So you’re saying it’s going to move beyond just being a note-taker to actually taking the next step — listening and acting on what’s discussed?

Bharat: It’s already there. It’s already happening.

Ritu: Most health system CIOs and CMIOs we speak with are now genuinely overwhelmed by the pace of innovation — something new seems to emerge every single day. How should they think about sequencing platform modernization, AI adoption, and operational transformation without creating decision fatigue within their organizations?

Bharat: Let me offer a few key points. First, start with the end in mind. Be clear about the outcomes you’re trying to achieve, and recruit the right solution for that. Second, don’t look at AI as a collection of a hundred individual vendors. Look for a partner who can help you establish a platform and services framework capable of solving hundreds of problems over many years. Those are the two axes I think are most important. What I see in the marketplace — even within our customer base and beyond — is that tens, sometimes hundreds, of startups and AI companies are approaching health system leadership from every direction with different point solutions. Each of them genuinely has something to offer and can solve a specific problem. But the challenge is: how do you bolt ten or twenty different AI startups into your ecosystem? Every model requires data, which means you’re extracting and sending data to various external environments and then managing the cybersecurity, data privacy, and compliance implications of each one. AI has already proven itself enough that every health system should accept it is part of their journey. So you might as well embrace it and start forming a trusted partner framework — identifying which partner or set of partners can help you establish an AI infrastructure within your organization, connected to both your clinical and enterprise systems, to achieve clinical, operational, and financial improvement. Think from a partnership perspective. Then think with purpose — what are the highest-impact starting points? What has already been proven in the marketplace? Adopt that, but don’t wait for the next wave to perfectly emerge. Some degree of experimentation and piloting is important in this space, and in AI the pilot cycle is measured in days and weeks, not months or years, because that’s how efficiently you can deploy an AI agent and get to outcomes.

Ritu: Do you see a tension there? In most industries, the mantra is innovate fast and fail fast. But in healthcare it’s almost the opposite — you have to play it safe and not take chances. How do you reconcile those two?

Bharat: You raise an important point. In virtually any other industry, a parts-per-million error rate might be acceptable. In healthcare, it is not. So you absolutely must have guardrails — and that’s exactly why you need a trusted partner and platform with appropriate governance built in. While you may be doing early adoption of innovation, you need the right guardrails, the right governance, and the right metrics to ensure absolute patient safety. You also need to be able to test high-risk scenarios in a non-production environment. But here’s the opportunity: there is so much improvement to be made on the operational side of healthcare that you can safely deploy AI to solve a significant number of operational problems and gain efficiency before you move toward higher-stakes clinical applications. That gives everyone a meaningful runway to get started in a big way.

Ritu: Where we’re seeing most implementations right now is in the digital front door — before the patient even reaches the clinical setting. But do you think the guardrails and safety factors you described will keep humans in the loop longer? AI is progressing so rapidly — we’re already hearing about AGI, and we saw with Project Strawberry that some organizations are pausing releases to give the industry time to assess vulnerabilities. Do you think the human-in-the-loop model can hold, or will AI leapfrog that?

Bharat: That’s where careful governance and guardrails are essential, because no one can afford to simply wait. The question is how do you keep moving forward while doing so safely. I think establishing clear frameworks helps — for example, if something is purely administrative and doesn’t directly impact patient care or patient safety, it could potentially be automated. That’s the invisible AI piece. You just need the right metrics to confirm it’s achieving the intended outcome. You can do that very safely on the operational end. But the moment you inch toward anything that assists — not even makes — clinical decisions, then transparency becomes paramount. The AI must show why it’s drawing a particular conclusion, and it should be assistive and presenting facts with full transparency to the clinician rather than acting autonomously. For example, in our new EHR, every time a physician logs in, an AI-driven summary is immediately generated — one that knows the patient, knows the reason for the visit, knows the physician, and has access to the entire longitudinal record. It constructs a concise summary a clinician can consume in one to two minutes, versus clicking through fifteen tabs over ten minutes on a complex patient. But critically, we’ve embedded metadata tags throughout that summary. Anywhere there is critical information, the clinician can hover over it and see exactly where it came from — and with one click, the source document loads with the relevant text highlighted. That’s AI driving clinical efficiency in a way that’s also transparent and safe. We’re fortunate to have the full Oracle Health AI infrastructure stack combined with three to four decades of clinical system development experience. We understand the clinical significance of every data element and its metadata. A lab value isn’t just a lab value — we understand what abnormal, high, and low mean, the standard deviations, and the source context, because we’ve been living with that data on the Cerner side for decades. Combined with Oracle’s capabilities, that puts us in a stronger position to deploy AI safely.

Ritu: You made very good points — retrieval-augmented generation with traceability back to the source, and the importance of context because you have so much surrounding information to interpret each value accurately. That was a very insightful answer. Time has flown by and we’re almost at the end of the podcast. What are your predictions for the next year? If we had this conversation again in a year, what would we be talking about?

Bharat: I think we’ll be talking about the next chapter — moving away from documentation and truly into orchestration. That’s the big shift. And AI shouldn’t be creating work; AI needs to do the work. I think we’ll see more successful examples of that. At the end of the day, all of this only matters if our clinicians and patients feel they’ve gotten time back, are doing fewer repetitive tasks, and feel there’s a safer path toward better healthcare. That’s the north star. Health systems should feel they can operate a better care delivery model. Providers should feel they’re delivering safer, better care while remaining personally satisfied — not overburdened. And patients should feel that the health system they’re visiting, powered by AI, is delivering a genuinely better experience. That’s the north star we’re working toward.

Ritu: Thank you so much, Dr. Sutariya. It’s been an absolute pleasure having you on the podcast. Thank you for making the time to speak with us today.

Bharat: It’s my pleasure. Thank you for a great conversation.

 

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Building Strategy-Driven Technology in Rural Health Systems

Season 7

Episode 205 - Podcast with Linda Stevenson, Chief Operations & Information Officer, Fisher-Titus Health
Building Strategy-Driven Technology in Rural Health Systems

The Big Unlock
The Big Unlock
Building Strategy-Driven Technology in Rural Health Systems
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In this episode, Linda Stevenson, Chief Operations & Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation under significant resource constraints. Leading a 100-bed community hospital with a lean IT team, she highlights the realities of “doing more with less”—from workforce shortages to the critical need for interoperability in coordinating care beyond organizational walls.

Linda challenges the industry’s fixation on AI as a standalone strategy, advocating instead for a problem-first approach: start with the clinical or operational need, then determine if AI is the right fit. She emphasizes that true transformation comes from aligning technology with enterprise priorities, not chasing hype.

She also points to persistent gaps in interoperability and growing cybersecurity risks, particularly in rural settings where vulnerabilities can impact the broader ecosystem. Her message is clear: stay grounded in strategy, focus on outcomes, and prioritize partnership over products to drive meaningful, scalable change. Take a listen.

This guest appearance was facilitated through conversations initiated at ViVE.

About Our Guest

Energetic and passionate digital leader with a masterful track record in transforming organizations to drive greater business outcomes and empower people through technology.

Linda Stevenson is a Certified Healthcare CIO (CHCIO) and serves as Chief Information Officer at Fisher-Titus Health in Norwalk, Ohio. With over thirty-five years of experience in the healthcare sector, Ms. Stevenson has directed transformative initiatives across clinical, operational, and revenue cycle domains at institutions including The Cleveland Clinic, MetroHealth, Southwest General, and Oracle Health Corporation. Her areas of expertise encompass project management, compliance, data security and privacy, regulatory, and system implementations.

Ms. Stevenson holds an MBA from Cleveland State University and is a Project Management Professional. She has been recognized as a top CIO to watch by Becker’s, nominated for the OHA Healthcare Worker of the Year award, and awarded a CHIME Healthcare CIO Bootcamp scholarship.

She is committed to advancing collaboration and innovation within the healthcare industry, serving on the boards of CHIME and Clinisync, and leading the Ohio Users Group for Oracle Health organizations. Ms. Stevenson has coordinated statewide CIO support networks and contributed to advisory boards and committees, including the CHiME and AHA Public Policy Groups, Ohio Health Partnership (OHIP) and Northeast Ohio HIMSS. She participates in national initiatives such as the KLAS Emerging Solutions Top 20 and Gartner industry groups and represented rural healthcare at the 2025 Senate HELP Committee hearing on cyber security.

Beyond her professional responsibilities, Ms. Stevenson is a wellness coach, master yoga teacher, aromatherapist, Reiki Master, Cancer Exercise Specialist, and health advocate.


Ritu: Hi everyone. A very warm welcome to all our listeners to Season Seven of the Big Unlock Podcast. My name is Ritu, and I’m your co-host along with Rohit, who is missing from the podcast today. We are very happy to have with us Linda Stevenson. She’s the Chief Information Officer at Fisher Titus Health, where she leads enterprise technology strategy for a community-based health system. She has over 30 years in healthcare IT, and has worked across organizations like Cleveland Clinic, Cerner, and regional hospitals. Her work has focused on integrating core systems, particularly EHR and telehealth. She’s especially passionate about advancing innovation in rural and community health systems where resources are constrained but impact is critical. We are really looking forward to our conversation today. Welcome once again, Linda, to the podcast. Thank you for being here.

Linda: Thanks for having me.

Ritu: I gave an introduction, but feel free to add anything you’d like or if you feel I missed anything.

Linda: I’ll give you a little background on me and my organization. Fisher Titus Health is a rural healthcare organization in northwest Ohio, in a town called Norwalk. We’re a 100-bed hospital facility — not a large hospital, but we offer a lot across the full span of a patient’s life, all the way from birth to end-of-life care, including nursing home care, skilled nursing, and home health. We also have a large physician practice group, so we really do span a wide range of care delivery areas. I talk about doing more with less — that’s what happens in rural healthcare. We are technically a rural healthcare organization, and our job is to figure out how to do things for less money but still achieve the same outcomes and access the same technologies as larger organizations. I love being in rural healthcare because I get to work on very challenging and creative solutions. And as of the beginning of March, I am now also the COO of the organization, handling not only the technology group and cybersecurity, but also all of our ancillary services, facilities, and environmental services.

Ritu: Wow. Congratulations — that’s great to know. As I was reviewing your profile, I realized you have somewhat of an unconventional background for someone in this position. We would love to hear your origin story — what brought you into healthcare and how you got to where you are today. I remember when we spoke, one thing really hit me: you said you have to reach out and ask for things, you can’t just sit back and wait for people to tell you what to do. You have to be confident in your own abilities. Tell us a little bit more about that.

Linda: I started in healthcare as a biller, typing bills on a typewriter back in the day, before all the automation we have now. I found that my passion was asking questions — I was always asking why in that department. The technology team noticed that and said that’s the making of a good analyst, and brought me into technology for the first time very early in my career. I had no computer background from an education standpoint — my degree was in business management. I used to joke it was a useless degree, but I found it certainly helped me later in my career as I moved into project management and building stakeholder relationships across the organization. From those early analyst days, I moved into project management, data security, and then progressively larger EMR implementations. I worked on the Epic implementation when it initially rolled out at Cleveland Clinic, and then had the privilege of working for Cerner — Cerner at the time, not Oracle Health — for three and a half years, really learning what the vendor side looks like through their IT Works division. And here I am as CIO years later. I always tell people: if you’re not sure, say yes. Every single opportunity I said yes to, even when I was afraid or thought it might not be my job — every single time, it opened another door and taught me something new that got me to where I am today.

Ritu: That reminds me of something I read — just jump into the pool and figure the rest out as you go.

Linda: That’s exactly how the COO role came about. The gentleman in that role was retiring, and I just went to my boss, the CEO, and said: put my hat in the ring. I have no idea what I’m doing, but I’ll figure it out.

Ritu: Awesome. So Linda, you’ve seen the full stack of hospital operations — from billing all the way to IT leadership. How has that shaped your view of what a CIO should prioritize today? Should it be innovation? Cost control? Operational reliability? Tell us about your priorities and how you balance these competing demands.

Linda: The easy answer is: yes, it’s all of that. I don’t think we can choose one thing, and I think that’s both the challenge and the beauty of what we get to do. At the bottom line, it’s about partnership — partnering with all the other leaders, whether nursing, finance, or operations, to understand the challenges they face. In some areas the challenge might be optimization or productivity improvement. For example, our therapy departments are struggling to recruit right now. They simply cannot find therapists. So how do we use technology to allow the therapists we do have to work faster while still delivering the same quality, so they can see more patients? It’s not about wanting to reduce headcount — we can’t even find people to hire. In other areas, the question is how to cut costs, through things like application rationalization: really honing in on using the solutions we already have better and getting the most out of our investments. And then there’s automation — some of it is simply about making lives better, whether that means giving patients better access to care or giving providers tools to reduce stress and burnout in their day. It really is all of it, and you just have to understand your audience.

Ritu: You’ve talked about bringing Fisher Titus back to Most Wired status. How do you ensure that’s based on measurable clinical or operational outcomes rather than chasing shiny objects? At VIVE, we heard everyone going after AI just to make it look good.

Linda: I’m a very practical person. About two years ago when everyone was still asking “what’s your AI strategy,” I’ve been around this industry long enough to know that AI is just another tool. We’ve had lots of tools — cloud was a buzzword for a while, EMR was a big thing. Lots of things come and go. Yes, this one might be a bit more impactful than some we’ve seen in the past, but the way I look at it: I don’t have an AI strategy. I have a strategy. The organization has a strategy, and we have a technology strategy to support it. That strategy may or may not involve AI — it depends on the need. I look at it from a practicality standpoint, going back to what we just discussed: partnering with leaders in each area to ask, what problem are you trying to solve? Then we look at whether there’s an AI solution, and whether it brings productivity improvements, cost savings, time savings, patient satisfaction improvements, or quality care improvements. All of those are measurable. That’s the conversation we have: here’s what we’re trying to solve, here are some options, and here’s what we think we can achieve.

Ritu: What we’ve heard from other C-suite leaders is that this has to be cross-functional — you have to build buy-in and partnership across the organization. Are you finding the same at Fisher Titus? And how are you tackling AI literacy, given that every couple of days there’s a new release and it’s hard for anyone to keep up? You said you’re not chasing shiny objects but focusing on strategy — yet you still have to know what’s out there. How does anyone keep up with this pace of innovation?

Linda: You try, right? There are a couple of factors. On one hand, our leaders need AI education to help them understand the basic things they can already be doing to make their lives easier — whether it’s ChatGPT, transcription tools, or other things that can lighten their administrative load. They often don’t grasp those as readily as they understand a vendor coming in and saying “I can solve all your problems with this new scribe solution.” So there’s a parallel track: here’s how you can help yourselves, and here are some broader things we can bring to the organization. At the same time, we have to temper the vendor conversations. Every vendor comes in with shiny objects, and I have to help them understand our strategy. We’ll look at what they offer, but it may or may not fit into the direction we’ve chosen, because we want integration across the whole — we don’t want 30 different scribe solutions or 20 different quality solutions. Vendors are generally receptive to that once you explain the why. You have to spend time on the why — educating them on how powerful these tools can be when done well, versus just buying something random.

Ritu: I think buy-in is the key. Once you have that trust, things move forward. Without it, it gets really difficult.

Linda: And isn’t that the key — trust? They need to trust us and we need to trust them. That’s something we’ve been building for years. It’s not a new thing.

Ritu: You’ve worked both inside health systems and with vendors like Cerner, so this question feels very pertinent. Where do you think the industry still overestimates interoperability, and where are we still fundamentally constrained by vendor ecosystems? Most of these ecosystems remain fairly closed, and now everyone is asking how AI is going to suddenly change that. We heard the recent announcement from Epic about building AI agents into their workspace. What are your thoughts?

Linda: All the EMR vendors are building AI agents — they all have it at various stages of development. The ERP vendors are doing the same. Interoperability has been a conversation since about 2008 when Meaningful Use first started coming out. It’s frustrating because Fisher Titus has engaged with every opportunity to be interoperable where possible. We’re connected to CommonWell, to everything through the HIE — all of it. But that doesn’t mean the information flowing through is in a form that clinicians can actually use. That’s where we still struggle. As a rural healthcare organization it’s especially challenging, because unlike a large integrated system like Cleveland Clinic or Mayo Clinic that has all specialties and services within their own walls, we don’t. We refer a lot, so interoperability is critical for continuity of care. But not all information flows through traditional interoperability channels. A great example: maternity records. A delivery record or a nine-month care plan for a patient is not coming through on a CCDA. We still fax paper records back and forth to outside OB physicians. Interoperability still has a long way to go.

Ritu: That’s what we’ve been hearing from everyone. Even with telehealth — we expected it to drive deeper EHR integration, but we’ve still seen patchwork systems and ongoing problems with embedding telehealth into core clinical workflows. What has your experience been?

Linda: It’s very patchworked. We try to connect wherever possible. I’m actually on the board of directors for Ohio’s state HIE, and I’m very proud of the work Ohio has done — building a really robust HIE that goes well beyond just sending CCDAs, including data exchanges for population health initiatives and supporting state Medicaid. The more you can get involved at the state level, the more you can help shape the bigger picture. Working with fellow CIOs and leaders to ask what we can all do better — that’s where the real conversation needs to happen. And then taking that up to the federal level, so we can ask for exactly what we need rather than having proposals come from people who have never actually worked in healthcare.

Ritu: We’ve been hearing from other health systems and CIOs that they’re driving innovation through internal innovation arms or venture studios. Does Fisher Titus do any of that?

Linda: No. At a rural hospital you generally don’t see that. My entire IT team is 35 people — covering help desk, technology, clinical analysts, informatics, trainers, cybersecurity, everything. That’s our scope. We’re not doing a lot of in-house development. We work through vendor partnerships, and I strongly believe in developing strong relationships with those vendor partners to drive innovation.

Ritu: Linda, we saw that you recently submitted a brief for the Senate Health Committee. Tell us more about that — we would love to hear about your role.

Linda: What a wonderful experience that was. Last summer I had the privilege of going to the Senate Health Committee to talk about rural healthcare, cybersecurity, and the risks facing all of us. Every healthcare organization is exposed to this ongoing onslaught of cyberattacks. But rural healthcare has such small budgets and limited resources that it’s really hard to keep up and protect ourselves — and all organizations are connected through us in one way or another. We’re a link in a chain, and if we’re weak, the entire healthcare chain is weak. I was really trying to highlight that challenge: the difficulty of recruiting cyber professionals, the cost of managing third-party vendor risk. It was a great opportunity to speak up, and actually I’m going back to Washington this week to speak with the Healthcare Sector Cyber Working Group at an all-hands meeting. I’ll be on a panel there talking about these ongoing challenges.

Ritu: That’s great — really important work. I read the briefing you submitted and thought it was very well written. You made some really strong points. I’ve been watching a show called The Capture, and it’s shown how easy it is to use deepfakes to get into systems. Just like you said — once they find the weakest link, that’s all they need. The entire chain has to be strong.

Linda: One of the things I focus on so much is connection and networking, because who in this day and age can do it alone anymore? There’s just too much. Connecting with people like you, with my peer groups, and with CHIME — who also supported me through that Senate Health Committee process — those relationships are invaluable. Vendor relationships too. As leaders we have to stick together to raise the tide for all.

Ritu: Exactly. Time always goes by fast and we are almost at the end. Any forward-looking final thoughts you’d like to share? Where do you think this is all headed, and where do you think we’ll be a year from now?

Linda: I think it goes faster than we think it will, and it’s really hard to keep up. A year from now the conversation will look very different — we’re already starting to see the shift in what AI can actually deliver and what it will actually cost. My final piece of advice: take a deep breath. Think it through. Don’t rush into a million shiny objects. Stick to your strategy and focus on where technology will genuinely benefit you. And don’t forget to take care of yourselves — when we work at this pace, it’s really important to stop, regroup, and refocus on your own health.

Ritu: Thank you, Linda. It’s been a pleasure having you on the show. Thank you so much.

Linda: Thank you. Great to see you.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Why AI Won’t “Replace Doctors” But Will Redesign How Care Is Accessed and Paid For

Insights by Roy Schoenberg, M.D., CEO, Aileen, and Founder and Executive Director, Amwell

Key Takeaways

  • Telehealth failed because it replicated visits instead of redistributing expertise. 
  • AI adoption will be driven by cost incentives. 
  • Payers may launch AI-first insurance plans. 
  • Seniors need relationship-based AI, not reminder apps. 
  • AI will become healthcare’s “surround system.”

“Telehealth can be a channel, or it can be a switchboard.”

That’s how Dr. Roy Schoenberg frames one of the most important misunderstandings of virtual care. For more than a decade, telehealth has largely been implemented as a substitute for the traditional office visit, basically, the same encounter, delivered through a screen. Useful, convenient, and often necessary, but ultimately limited.

Schoenberg argues that this isn’t what telehealth was supposed to become.

A physician by training and one of the pioneers who brought telehealth into mainstream U.S. healthcare through Amwell, he has spent his career operating at the intersection of clinical care, technology, policy, and large-scale systems. After leading Amwell through its growth into a foundational platform for payers and health systems, he stepped into his next venture with a bold thesis. AI will become the primary entry point to healthcare, and its biggest early impact may come not from flashy interfaces, but from simple, relationship-driven interactions, especially for seniors.

His new venture, Aileen.ai, is built around that belief. And the story he told our host on a recent episode of the Big Unlock Podcast isn’t a “telehealth recap.” It’s a provocative forecast of how AI will reshape the economics of access, the structure of care journeys, and the missing human support that millions of seniors increasingly need.

Listen to the full conversation

Telehealth’s missed opportunity: replacing visits instead of redistributing expertise

Schoenberg’s answer to host Ritu M. Uberoy’s first question is direct: Telehealth has largely been used as another channel for the same clinical encounter. A visit or follow-up visit that used to happen in the office now happens via video. That creates convenience and some efficiency. But it doesn’t fundamentally change the healthcare system. He refers to this as “model one.” 

He then presents his “model two,” which he says is where the disruption lives. Telehealth “as a switchboard’ that reshuffles how expertise is acquired and delivered.

He offers a clear example. If you live in Boston, cancer expertise is concentrated in world-class centers. But many parts of the country don’t have that depth of specialty care. Telehealth’s deeper promise is not just letting a local doctor do a video visit; it’s enabling expertise to flow at scale, so patients and clinicians in underserved regions can access high-quality specialty care without relocating.

In his words, this would “democratize” services at a much larger scale.

So why hasn’t it happened?

Schoenberg points to the system’s protectiveness and the “muscle memory” of healthcare. Licensure, credentialing, reimbursement, and entrenched workflows make it difficult to redistribute expertise. He’s candid about underappreciating how resistant the system would be to this kind of restructuring.

But he also makes a strong claim: the train has left the station. Post-COVID, the idea that care will be redistributed through technology extends beyond any one platform or company. It may move slowly, but it’s inevitable.

That sets up his next point: AI will accelerate the switchboard model far more than traditional telehealth ever could.


AI will become the front door because of economics, not because it “beats doctors”

A lot of the public debate about healthcare AI gets stuck in a single question: can AI be a doctor?

Schoenberg doesn’t dismiss that question, but he argues it’s not the real trigger for adoption.

He believes AI will become the primary entry point to healthcare for a simpler reason: economics. AI is highly accessible and far cheaper than clinician time. That means the earliest large-scale adoption will be driven less by persuasion —“AI is better than your doctor”—and more by incentives—using AI saves you money”.

His most provocative prediction is that the true inflection point will come when payers introduce an insurance product that requires members to interact with AI first. He compares it to the gatekeeper model of the HMO era, except the gatekeeper won’t be a primary care physician. It will be AI.

He acknowledges that pure restriction won’t be popular. The product will need to be designed “smartly,” with a break-glass option to see a clinician when needed. But the direction is clear: the more you use AI, the more you save. Shared savings models and cost-driven pathways will shape behavior.

This matters because it reframes “AI adoption” as a system design and insurance design problem ,not just a clinical intelligence problem. If the payer controls the front door and aligns incentives, AI doesn’t have to win a philosophical argument. It wins by being the default.

Schoenberg also notes a reality we’re already seeing. People are using general AI tools for health questions at scale, often as a preparatory step before seeing a clinician. That creates a gradual normalization effect. Patients build comfort by asking questions, receiving explanations, and forming a first draft of what they want to discuss.

In his view, this is the beginning of AI as the “surround system” for the healthcare experience, an inevitable layer that wraps around access, triage, navigation, and follow-up.


Why “staying power” is the real breakthrough for seniors and caregiving

If the first half of the episode is about how AI will restructure the front door, the second half is about a different problem entirely. The “caregiving gap.”

Schoenberg describes a sobering demographic reality. The senior population is growing rapidly, while the availability of caregivers is shrinking. Senior care is emotionally and physically demanding and often underpaid. Many people don’t want those jobs. The gap between need and available support is widening.

His claim is blunt. “Houston, we have a problem…”

There’s already a massive “age tech” market, apps, chatbots, talking devices, pill boxes, and reminder tools. Many are well-intended, but he argues most fail for one consistent reason. They don’t create adoption or “staying power.” Seniors have a complicated relationship with technology, and tools that feel like nagging reminders create fatigue. They “die on the vine.”

His latest venture, Aileen.ai, is built around a different premise.

If technology is going to meaningfully influence a senior’s life, the first job isn’t telling them what to do. The first job is becoming a wanted presence in their day, something they choose to engage with.

Schoenberg defines staying power as something that comes from familiarity and relationship. In real life, staying power comes from people who know you, who remember your kids and grandkids, your joys, frustrations, and stories. Aileen is designed to create that kind of familiarity through AI.

And he emphasizes the real technical challenge: none of that “personal narrative” exists in a database. Nobody wrote a book about your dad. So if AI is going to know a senior deeply, it has to learn that reality over time.

He also points out a behavioral constraint. Most AI today is prompt-driven. We type something in, and AI responds. That interaction model won’t work for seniors. If you wait for seniors to prompt, you’ll wait forever. So Aileen is designed to initiate engagement.

That’s why the interface choice matters. Aileen uses the phone. It calls seniors. It doesn’t require them to download an app, log in, pair devices, or even have Wi-Fi. The “backend” may be rocket-science AI, but the front end is intentionally simple and familiar.

Schoenberg calls this combination “schizophrenic” in the best way. Delivering “science-fiction technology” behind a human, everyday interface.

He also describes another distinctive element. Aileen builds intimacy by learning from the people who already know the senior. It can call family members casually, without forms or scheduled meetings, to gather context and build an understanding of the senior’s life. Only after it crosses a threshold of “knowing enough” does it begin daily engagement with the senior. Then it loops back insights to family members. He describes it as like having a lightweight companion and monitoring layer that helps shoulder the burden families carry.

Critically, Aileen isn’t designed to talk about “healthcare” all day. It’s designed to talk about what seniors want to talk about, because relationships are what create engagement. Once that staying power exists, Aileen becomes a mouthpiece for other healthcare technologies: reminders, symptom monitoring, mood and cognitive signals, and supportive guidance.

Schoenberg’s bet is that relationship is the missing prerequisite to successful senior-facing health technology. Without it, the reminders don’t stick. With it, they do.


AI is inevitable, but it will mature through trial, error, and redesign

Schoenberg closes with a realistic forecast. AI is young. We will see a long maturation curve. There will be mistakes. There will be things to worry about. But he believes AI’s role as a foundational “surround system” in healthcare is inevitable.

His message is basically: if we know we’re going there, we have to start walking.

That’s what he believes Aileen represents: an early attempt to solve a hard problem the system can’t ignore: a widening caregiving gap and a need for technology that doesn’t just function, but persists in daily life.

He’s confident in the ambition: in his words, this could change the world “no less than what telehealth did.” Whether one agrees with the magnitude or not, the through-line is consistent: the next era of healthcare won’t be defined by a single app or a single visit channel. It will be defined by AI as the first touchpoint, the navigation layer, and perhaps for the most vulnerable among us, an ongoing relationship that helps people stay supported at home.


The Takeaway

Dr. Roy Schoenberg’s message is both pragmatic and bold. Telehealth’s real promise was never just “video visits.” It was the ability to redistribute expertise and reshape care journeys at scale, and AI will finally push healthcare toward that switchboard model by changing the economics of access. In his view, AI won’t become dominant by proving it is “better than doctors,” but by becoming the default entry point through payer-driven incentives that reward AI-first navigation while keeping a break-glass path to clinicians. 

Sitting at the intersection of telehealth platform-building and the next wave of AI-driven care navigation and companionship, Dr. Schoenberg’s unique insights are especially valuable:

  • Telehealth was mostly used as a substitute channel; its deeper potential lies in acting as a switchboard that redistributes expertise and democratizes access. 
  • AI will become healthcare’s front door primarily because of economics—accessibility and cost—not because it “proves” it’s better than doctors. 
  • The real adoption trigger will be payer products that require AI-first interaction, with shared-savings incentives and a “break-glass” path to clinicians. 
  • The senior care crisis is a demographic reality: need is rising while caregiver supply is shrinking, creating a gap that technology must help fill. 
  • Most age-tech fails because it lacks staying power; seniors disengage when tools feel like nagging reminders without a relationship. 
  • Aileen’s differentiator is relationship-driven AI delivered through simple phone calls—building familiarity first, then enabling reminders and support to stick.

AI Adoption in Healthcare Must Be Led by Clinicians

Season 7

Episode 204 - Podcast with Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital
AI Adoption in Healthcare Must Be Led by Clinicians

The Big Unlock
The Big Unlock
AI Adoption in Healthcare Must Be Led by Clinicians
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In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care settings. Dr. Garg highlights how COVID accelerated digital adoption, from telehealth to remote patient monitoring, demonstrating that care can be both accessible and efficient when technology is thoughtfully applied.

Dr. Garg underscores that AI’s true value lies in reducing administrative burden, particularly in areas like documentation and prior authorization, where inefficiencies delay care and strain clinician-patient relationships. She notes that ambient AI is already improving accuracy and saving hours for physicians, with the next wave extending into orders, workflows, and care coordination.

However, she emphasizes that successful adoption depends on clinician involvement, intuitive design, and minimizing workflow friction. While AI may take on more clinical decision-making, questions around trust, liability, and human oversight remain central, making it critical for healthcare leaders to actively shape, not resist, this transformation. Take a listen.

This guest appearance was facilitated through conversations initiated at ViVE.

About Our Guest

Dr. Ruchi Garg is the Chief Medical Officer of Fairview Park Hospital, a part of HCA system. Dr. Garg brings over 25 years of clinical experience. In the past, Dr. Garg was the Chair of Gynecologic Oncology for all of Cancer Treatment Centers of America Hospitals that was acquired by City of Hope.

Board certified in Gynecologic Oncology and Obstetrics/Gynecology, Dr. Garg has taken care of over 10000 gynecology and gynecologic cancer patients and has a strong interest in cancer prevention. She has performed over 3,500 robotic surgeries.

Dr. Garg developed an interest in digital health – telehealth and remote patient monitoring at the start of the COVID-19 pandemic. She has established several digital health programs and continues to be intricately involved with health tech startups.

As part of the six-year honors program in medicine, Dr. Garg completed her BS and MD at University of Miami, Florida. She completed her residency in Gynecology and Obstetrics at Johns Hopkins in Baltimore, Maryland and Gynecologic Oncology fellowship at the University of Washington in Seattle, Washington. Dr. Garg completed her Executive MBA from Kellogg School of Management at Northwestern University, Evanston, IL. Dr. Garg has received several research awards and has had many publications and book chapters. She has held several academic Associate Professor appointments including at City of Hope, Uniformed Services, UVA, George Washington, and the VCU School of Medicine. Dr. Garg has served on multiple national committees for American Society of Clinical Oncology and Society of Gynecologic Oncology.

She has won numerous top doctor awards, including being spotlighted on the cover of Washingtonian Top Doctors. She serves as a board member for the Joy Clinic, Dublin, GA.

Dr. Garg enjoys spending time with her family and friends. She enjoys sports and athletic activities. Dr. Garg enjoys traveling and learning about other cultures, history, and seeing the beautiful sites on this Earth. She can’t wait to show the world to her 6-year-old son.


Ritu: Hi everyone. Welcome to our Big Unlock Podcast. My name is Ritu and I’m the co-host of the podcast. Really happy and excited to have Dr. Ruchi Garg here with us today. This is Season Seven of our Big Unlock Podcast — a very warm welcome to all our listeners. We are really inching towards 200 episodes, so we are very excited. It’s been going on for a while and we are always happy to bring you fresh perspectives. Dr. Ruchi Garg is our guest today. She’s the Chief Medical Officer at Fairview Park Hospital, where she’s deeply engaged in delivering high-quality, patient-centered care in a community hospital setting. She’s a gynecological oncologist with a demonstrated history of working in the higher education industry, and her work reflects a strong commitment to advancing care delivery through thoughtful adoption of technology and process innovation. She’s particularly passionate about addressing physician burnout and enhancing care access for diverse and underserved populations. Today she’s joining us on the Big Unlock Podcast to share her insights on the evolving role of clinicians in shaping the future of healthcare. Really happy to have you here with us, Dr. Garg. Welcome.

Ruchi: Thank you for having me, and thanks for that generous introduction. I look forward to a wonderful conversation today.

Ritu: Our listeners always love to hear an origin story. Now that we’re coming up on 200 episodes, we still hear such interesting things when we ask people how they got into healthcare and into this intersection of healthcare and technology. We’d love to hear what your inspiration was, what led you into healthcare, and what keeps you going. What motivates you?

Ruchi: It’s interesting — I always tell a funny story about what got me into healthcare. Being of Indian origin, growing up we used to laugh that Indians always become either engineers or doctors. In 10th grade, I still remember doing a summer electrical physics course, learning all about circuitry, and it dawned on me in the middle of that summer that I was not going to be as good an engineer as my dad — so I decided to become a doctor.

Ritu: By the process of elimination!

Ruchi: Well, I was mathematically inclined, a STEM child — and thinking about how I could make a bigger impact on the world. My family has always believed that you don’t have to follow your parents’ pathway; you have to build upon it and contribute more. That’s really what led both my brother and me into medicine. Going through medical training, I actually never thought I was going to be a surgeon and a GYN oncologist. I thought I was the child who was going to faint at the sight of blood, and there are some funny stories from medical school. But I loved my surgical rotation — I loved the immediacy of impact you can have on a patient’s life. The more complex the surgeries were, the more I loved them. I remember going through the hepatobiliary rotation and doing Whipple procedures — massive pancreatic or liver resections — and I loved every minute of those six-to-eight-hour surgeries. Then I went through the GYN oncology rotation and I was hooked. GYN oncologists are definitely a unique breed. We love to work hard and play hard, and it’s a unique subspecialty because you get to stay with your patient throughout their entire journey. I’ve had patients as young as eight years old, unfortunately, and as old as 96. I’ve done prophylactic surgeries and prevented cancers in high-risk patients. I’ve diagnosed cancers, done surgeries, treated patients through chemotherapy, and also held their hand when they’ve passed. That’s what attracted me to GYN oncology — we’re trained to do all of it: prophylactic surgery, complex surgeries, chemotherapy, end-of-life care, and building that relationship with our patients.

Ritu: Thank you — it’s very inspiring to hear. The amount of effort and work you put in is incredible. I’m always in awe when I talk to physicians. It really feels like a calling that goes way beyond a profession. So let’s talk about the favorite topic at the moment — at HIMSS you couldn’t walk more than a few steps without hearing about AI. In your current role, what do you see happening? We hear a lot about physician burnout and clinicians walking away from the field. Can you share a personal story where AI really moved the needle and helped you reclaim some time, or a particularly successful implementation that makes you feel this is a pivotal moment?

Ruchi: Let me step back a little to explain why I got hooked on health tech. The real taste came during COVID. I was in private practice in Northern Virginia at the time — a very busy practice that also did academic training with fellows and some research. We couldn’t skip a beat when COVID came because cancer didn’t stop. Within a week I was able to set up a telehealth program in my practice. Fortunately there were companies that had already been advertising, and we connected with them so our patients continued to get care. We also had our own chemotherapy suite, and those patients needed vitals monitored — but as you can imagine, they were a very vulnerable, high-risk population during COVID and we didn’t want to bring them into the office unnecessarily. I connected with a startup doing remote patient monitoring at the time, and we deployed monitoring tools to these patients so their vitals could be transmitted from home. We then did telehealth visits with those patients. The only reason they had to come into the clinic was for labs and infusions — really minimizing visits. The patients liked it because it was convenient and they didn’t have to come in for every single thing in their care paradigm. I was involved with a similar monitoring program at the cancer center after that and built upon it. But when AI technology really took over, there was so much more we could do. That’s where my interest in streamlining healthcare, building efficient protocols, having a more standardized approach, and intertwining that with day-to-day care using AI — that’s when the wheels really started turning. I was fortunate enough to partner with a company called Resa. Initially they were a space-agnostic, AI-based prior authorization company. Within two months of being brought on as an advisor, we had many long conversations and realized that oncology was where we could make the biggest impact. The company shifted their focus to that space, because with an oncology patient you’re getting prior authorizations for every step along the way — prophylactic surgery, major surgery, CT scans, chemotherapy, and then if the cancer comes back, repeat chemotherapy, immunotherapy, radiation therapy. One patient, huge impact. And the prior authorization process has become really cumbersome. Fifteen or seventeen years ago when I started practicing, I would do a peer-to-peer review with an insurance company maybe once a month, if that. By the last few years of my practice — before I took on a full-time administrative role a couple of years ago — I was doing at least one or two peer-to-peers every week.

Ritu: Oh wow.

Ruchi: That’s quite burdensome, and it delays care. It adds anxiety for the patient and tension between the clinical team and the patient, because patients think you’re not doing your job — when in reality you’re working within the constraints to get things approved so they’re not stuck with a huge bill at the end, while also managing all your other patients. The buck doesn’t stop with one patient. That’s where these kinds of technologies are making a big difference and will continue to do so. But the key is that the company listened to me as a clinician. We can’t just throw technology around without having the voice of the clinician and the frontline folks involved in shaping it.

Ritu: Absolutely. I think a recurring theme is that COVID really normalized telehealth and kickstarted this whole wave, making it so much easier for people to accept virtual visits and remote monitoring like you’ve described. Great example — thank you for sharing. I was also asking about particularly successful AI implementations in your community hospital. Other than the oncology company, what has your experience been with ambient or voice agents?

Ruchi: I’m part of Fairview Park Hospital, which is a smaller facility within the larger HCA system. HCA has taken a very centralized approach to deploying AI technologies so they can do it in a controlled, standardized manner with guardrails around data protection and cybersecurity — a very thoughtful approach. What has been done so far is AI-based ambient listening for physicians. My physician services group doctors who are using this technology — mainly my surgeons — each say it has saved them about an hour and a half to two hours every day.

Ritu: That’s huge.

Ruchi: That’s huge. You can see how much burden that takes away — not just the physical strain, but also the accuracy. If you’re waiting until the end of the day to do your notes, you’re going to miss things. We don’t have time built in between patients to do documentation, so a lot of it happens at the end of the day. With ambient listening, documentation happens in the moment, which allows for more accurate notes and a faster turnaround. I was very intentional that my notes had to be done before I left for the day, but not every physician is able to do that — and even for me, there was probably at least 1% of the time I missed it. Then there’s a delay in care because the next day is already full — you’re just playing catch-up. There’s a lot of opportunity to build beyond that layer. Ambient listening can go deeper: AI can then fill in the orders that need to follow — the follow-up orders, the prior authorization forms, the request for surgery, the request for a CT scan. All of that becomes a faster and more accurate turnaround, even though it’s not fully deployed yet. I’m a hundred percent sure that’s the future.

Ritu: A lot of companies are working on exactly that — integrating it into the workflow rather than keeping it as a point solution. With agents, each one can just fire off and handle the next step. My next question is about your leadership role. When you’re leading clinical teams through change — whether it’s new technology, new protocols, or new care models — we hear a lot about responsible and trustworthy AI. What’s your approach to building trust that gets you true adoption rather than passive compliance? You can’t just dictate from tomorrow you’re going to use this. How do you actually convince physicians, who are already resistant to change and incredibly busy, to learn something new and integrate it into their workflow?

Ruchi: It really goes back to partnering with clinicians — or whoever the end user is. If it’s a provider solution, partner with the providers. If it’s a nursing solution, partner with the nurses. Understand the workflow and the user space, and focus on decreasing the burden. When you come from the perspective of making them better and more efficient, and showing how it’s also going to help the patient more — that’s the approach that works. Compare it to the EHR rollout, which is the prime example of what you’re describing. It was something everyone just had to swallow. It wasn’t built with clinicians in mind, and everybody talks about death by a thousand clicks. When I came into my role, one of the concerns my clinical informatics team brought to me was that clinicians weren’t discontinuing telemetry orders — the cardiac monitoring — when patients no longer needed it. They were good at ordering it but not at discontinuing it, so we were running out of telemetry boxes. I asked them to walk me through the workflow. It was one click to order telemetry. It was four clicks across four screens to discontinue it. That’s why it wasn’t getting discontinued until a physician needed the box for their own patient. It seems like a silly example, but when you add up those extra three clicks throughout the day for various things, that’s where you get the barriers to adoption. That’s how we have to think about AI platforms too. If we get doctors used to the fact that their notes are done, and they just need to review and take ownership of them — great. But then asking them to also sit down and enter all the follow-up orders when the technology could easily handle that — the human mind is going to want more, and that’s exactly the direction we need to go. We have to show how it benefits both the clinicians and the patients and keeps removing the burden.

Ritu: We’ve been hearing a lot about successful AI implementations for digital front doors, ambient documentation, and things somewhat removed from the actual practice of medicine. But now we’re slowly seeing a move toward AI doing more diagnostically — passing medical exams, with millions of people around the world turning to ChatGPT with their full health histories and getting back diagnoses. What are your thoughts on this trend? Where do you draw the line between what the physician does versus what AI can do? Should the human in the loop stay, and what’s the time horizon for that to change?

Ruchi: The writing is on the wall. We can keep denying it, but there is low-hanging fruit and standardized protocols that AI is already trained on. Do patients really need to see a doctor to be diagnosed with a URI and get an antibiotic prescribed? But if someone has had three or four infections in two months, you want the next level of critical thinking — and yes, AI will get there. With ambient listening, the AI is getting trained on clinical reasoning. As physicians make corrections and talk through their thinking, the AI is getting that deeper-level training. The writing is on the wall. The question is: who’s going to take the liability? That’s where medicine is hung up right now. It would be very easy to deploy AI decision-making in primary care settings, for example. But if the AI is hallucinating or producing an incorrect diagnosis — because there is a lot of gray zone, which is what we call differential diagnosis — who takes ownership of a bad outcome? Is it the AI company that gets sued? We live in a litigious society. Or is it the doctor who holds the malpractice insurance? I always say that doctors are not allowed to be human. We’re not allowed to make human errors, because if an error leads to a bad outcome, you face the consequences. AI removes some of the human factor but introduces other kinds of glitches.

Ritu: I totally agree. It’s a very evolving field. At HIMSS and VIVE, we heard a lot about health deserts — communities with no access to care. If AI can provide some care in a rural community, is that better than no care at all? It’s an interesting question and we’ll have to closely watch what happens.

Ruchi: Exactly — you hit the nail on the head. That’s where we’re going to have to show the benefit and deploy it. I’m a robotic surgeon by training too, and the robot was initially created by the Department of Defense to operate in remote settings and war zones. Very soon the question became: if the doctor isn’t at the bedside, who takes the liability? Even though that capability existed from the beginning, it never got deployed that way — the surgical team had to be in the room. Even now, robotics can perform basic, standardized surgeries like gallbladder removal or appendectomy. But again, who takes the liability?

Ritu: Dr. Garg, as usual this goes by really fast and we are almost at time. Thank you for being on our show today. Any last thoughts for our listeners or anything you’d like to leave them with?

Ruchi: The biggest thing is that the future is here. We cannot be afraid of it — we have to embrace it. That’s what I tell my physician colleagues: let’s look at the positives we can take away. There are definitely negatives and things to worry about. AI can talk very sweetly, but it does take away the human factor. There will be a generational difference in adapting to and accepting that — millennials versus baby boomers. But as physicians and as people in healthcare, we have to lead that and not sit back and let it define us the way we did with the EMR, or the way we let the payer-insurance system and the political environment around healthcare shape us. Let’s not let that happen with AI technology.

Ritu: That’s great advice. You have to embrace the change and be part of it so you can contribute to it and shape it for the greater good. Thank you, Dr. Garg — it was a pleasure having you on our show today.

Ruchi: Thank you for having me.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI Should Make Healthcare Feel More Human

Season 7

Episode 203 - Podcast with Ed Lee, MD, MPH, Chief Medical Officer, Nabla
AI Should Make Healthcare Feel More Human

The Big Unlock
The Big Unlock
AI Should Make Healthcare Feel More Human
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In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphasizes that the true goal of technology is not efficiency alone, but restoring the human connection in healthcare.

Dr. Lee explores why change management, not the technology itself, is the hardest part of AI adoption, and why clinician involvement from day one is non-negotiable. He challenges the early narrative around time savings, arguing that the deeper ROI of ambient AI lies in reducing cognitive burden, restoring joy in medicine, and rebuilding the patient-physician relationship. He also looks ahead to the next frontier: clinical decision support, diagnosis capture, and chart summarization woven seamlessly into workflows. Dr. Lee’s closing thought is simple but powerful – done right, AI shouldn’t feel technical. It should feel human. Take a listen.

This guest appearance was facilitated through conversations initiated at HIMSS.

About Our Guest

Ed Lee, MD, MPH, is a practicing internal medicine physician, physician executive, and nationally recognized leader in clinical informatics and ambient AI. He currently serves as Chief Medical Officer at Nabla, where he drives strategy and clinical innovation for an AI-powered ambient documentation platform that enhances clinician well-being and care delivery.

Previously, Dr. Lee was Chief Information Officer and Associate Executive Director at Kaiser Permanente, where he led groundbreaking digital transformation efforts across one of the nation’s largest integrated healthcare systems. His leadership advanced AI governance, expanded access to care through telehealth, and improved clinician experience through smarter EHR tools and digital infrastructure.

In parallel with his executive roles, Dr. Lee is Chair of Clinical Education and Director of Clinical Informatics at California Northstate University College of Medicine, where he oversees a technology-enabled curriculum and clinical education strategy.


Ritu: Hi everyone, a very warm welcome to our listeners for Season Seven of the Big Unlock Podcast. My name is Ritu and I’m the co-host of the podcast. We are very excited to have with us today Dr. Ed Lee. Dr. Ed Lee is a physician and healthcare executive leading clinical innovation at Nala, where he focuses on bringing AI into real-world care delivery. He was with Kaiser Permanente for a long time, and we have some very good questions about that for you today, Dr. Lee. At Nala, he’s working at the forefront of ambient AI and clinical co-pilots, helping translate cutting-edge models into tools that actually work in everyday workflows. With that introduction, welcome once again to the podcast, Dr. Lee.

Dr. Lee: Hey Ritu, thank you so much for having me. I appreciate it and I’m looking forward to the conversation.

Ritu: Thank you for being our guest today — really excited to ask you some interesting questions. Let’s get started. We all know that Kaiser Permanente operates as a fully integrated system: payer, provider, and care delivery. How did that structure shape your perspective on what good looks like in clinical workflows, and how did it influence your thinking when you were building tools at Nala?

Dr. Lee: I thoroughly enjoyed my time at Kaiser Permanente. That’s where I actually learned how to be a real practicing clinician — seeing patients, having a large panel of patients to take care of over decades. It taught me how important it is to use technologies that allow clinicians to focus on their patients. At the end of the day, what we want to do is deliver high-quality, personalized care, and quite often technology can get in the way of that unintentionally. What we want to do now, with that understanding, is build technologies that bring the human side of care back to healthcare — removing the friction that technology may have introduced between patients and clinicians, decreasing the administrative burdens that clinicians face, and really making patients the forefront of what we do every day.

Ritu: Great answer. That leads directly into my next question. From all your time at Permanente, what did you learn about the human side of adoption? Because that’s what we’ve been hearing from most of our guests recently — driving clinicians to change behavior versus resisting change, even when the technology is objectively better. AI is passing all these tests, beating doctors on benchmarks, and yet behavioral change is really hard. How did you grapple with that?

Dr. Lee: One of the things I always mention is change management. The change management piece is often the hardest part of implementing new technologies — it’s not the technology itself. The technology can often speak for itself. But making sure clinicians understand the why is critical. Clinicians are very scientific and results-driven; they’re looking for evidence about why things should be done. If you don’t come in with that mindset, and if you don’t involve clinicians from the very beginning of a new technology project, you’re often destined to fail. AI has been around for a short time relative to the grand scheme of how technology has been implemented in medicine, but the impacts are starting to be quite evident. You mentioned how AI can sometimes answer test questions better than human physicians and clinicians. But I still feel the AI out there is really there to augment the clinician and the experience clinicians have with their patients — not to replace them. It’s still up to the clinician to incorporate the information AI brings into the conversation. That human-in-the-loop component always needs to be there to make sure we’re doing the right thing for our patients.

Ritu: That was the conversation we were having six months to a year ago. But now, as we’re seeing more and more co-pilots doing more — going beyond drafting notes and actually suggesting clinical context — how do you maintain clinician trust and ensure that judgment isn’t subtly being outsourced to the system because it’s just so easy? Even in our world of writing code, we’re seeing how easy it becomes to just sit back and let the AI keep generating. The more you engage with it, the easier it gets to let it handle everything. What are your thoughts on that?

Dr. Lee: The easy thing isn’t necessarily always the right thing. What we see with AI-generated outputs is that sometimes they can be very convincing. I’ve done it myself — I’ve plugged things into ChatGPT and it sounds so well-written that it feels like it has to be the truth. But we know that current LLMs are essentially word prediction models generating text, and while they are quite often correct and often bring new insights into the way I’m thinking about clinical scenarios, what you get is based on what you put in. It often requires a clinician’s expertise to put in the right prompt and bring in all the right factors to get the right output back. That’s where I have some concerns about these tools being available to all patients directly — they may not understand all the factors that need to go into the system to get the right output. And without clinician expertise to filter, interpret, and apply it to a real-world scenario, you may run into situations where the output sounds very convincing but isn’t exactly what you need because of what went into it.

Ritu: Are you seeing that a lot? We’d love to hear about it in the context of Nala. A lot of the narrative around Nala’s tools focuses on saving physician time. But what are some of the less obvious yet most strategic forms of ROI that health systems should be paying attention to? As you’re saying — if easy isn’t always right, you can’t just focus on whether ambient is saving the physician eight minutes or sixteen minutes. What are some of the other metrics we should be looking at?

Dr. Lee: It’s a great question. Early on, physicians were reporting saving an hour or even a couple of hours a day, and that’s what the data was showing at the time. Since then, multiple studies have come out showing that the time savings per encounter is actually smaller than that, and some clinicians aren’t necessarily having less after-hours time. I think it varies from clinician to clinician — some are saving an hour a day, cutting into the pajama time they would otherwise be doing. But what I’ve found myself in using Nala and other ambient and AI tools is that it gives me agency. What I mean is that I’m now able to budget my time the way I want to in the care of my patients. I could rush through my day, compact it more using the AI tools available and finish early — or I could invest the time I want to invest in my patients and develop those relationships and be more thoughtful about the care I deliver. So the time I could be saving in the global context of patient care time could be more, but I choose to invest that time into developing relationships with my patients. One of the ROI points that was talked about in the past was time savings, but now a lot of the conversation has shifted toward cognitive load, cognitive burden, and the joy and meaning that clinicians can get from using these tools that they otherwise would not have. Burnout has been shown to decrease because of these tools, and it’s not necessarily related to time saved. It’s because clinicians are now doing what they went into medicine to do in the first place — not working on a computer or acting as a transcriptionist, but being a caregiver, a clinician, a scientist, bringing in evidence and applying that knowledge to improve the lives of the patients they work with. That’s where I see some of the biggest gains from using this type of technology.

Ritu: That’s a great answer and it allows us to unpack a lot more. I remember reading somewhere that because of ambient, doctors are actually articulating more — because they know that whatever they say is going to be registered. Because of that, patient satisfaction increases because patients feel the physician is being more communicative. So it’s not just about the time spent, but actually increasing communication with the patient and resulting in a more meaningful interaction.

Dr. Lee: It’s a really insightful observation, because it may not have been one of the things we expected when we first deployed this type of technology. But as time has gone on and experience has been gained, it really is a win-win situation. Patients do feel more engaged in the conversation and get more explanation from the clinician — and it’s sort of a byproduct of the clinician wanting the ambient technology to hear what they’re saying so it gets captured in the note. They don’t have to write it later, but the patients gain almost as much as the clinicians do through the process of making the technology work for both sides.

Ritu: Exactly. So that leads into the next question: if ambient is just the first layer, what does the next phase of AI co-pilots in healthcare look like, and how far are we from that reality?

Dr. Lee: Next steps are happening right now, even as we speak. You mentioned ROI earlier, and I think there are different ways of looking at it. There are the human factors and softer components — decreased burnout, increased retention, recruiting strong clinicians who are looking for organizations that have this technology ready and deployable. But also looking at diagnosis capture and coding, making sure those financial components — which are critically important within the healthcare system — can be captured accurately and justifiably. Accurate documentation is very supportive of those goals, and surfacing the right diagnoses, CPT codes, and ICD-10 codes are things that are happening now and continuing to be built up. Beyond that, chart summarization is being incorporated into documentation to make it more complete. There’s so much in a patient’s chart — sometimes decades of information — and being able to distill it down and surface the key points pertinent to the conditions being addressed, so the clinician can see that at the point of care, is happening now. Then transitioning that into clinical decision support — and I think that’s something clinicians would really be enthusiastic about adopting, as long as the trust factor is there. What I mean by clinical decision support is having AI surface potential diagnoses, treatment options, diagnostic tests, and orders at the point of care — or even before or after — and having all that happen seamlessly throughout the entire process: seeing the patient, documenting, entering orders, and surfacing clinical information that allows the best care to occur.

Ritu: That captures what I was going to ask next. In one of your earlier answers you mentioned friction, and I wanted to ask: in real clinical settings, where do you think AI still falls short, and what needs to happen for it to become truly invisible infrastructure? I think you’ve kind of answered that — to be truly invisible, it has to do more than just the ambient piece and get into all these other areas you’ve described.

Dr. Lee: I think it does, and the word friction is almost visceral to me — it’s just things that get in the way of what you really want to get done. The clinician’s goal is to provide the best care for the patient, but things have been introduced into the system between the patient and the physician over time through technology that technology can actually help remove. Some of the tools being developed now are amazing, but if something isn’t built into the workflow — if it adds five extra clicks per patient — clinicians just aren’t going to use it. So it’s not only what a tool can do, it’s how it does it and how it’s incorporated. It really needs to be thoughtful in terms of usability so that clinicians can actually adopt it. You can put a tool out there, but as the saying goes, hope is not a strategy. The strategy should really be around understanding the needs of the clinician and their workflows, and building tools into those workflows so that the technology is truly seamless and can be adopted and scaled easily. I talked about the change management piece earlier — it all comes back to that.

Ritu: Thank you, Dr. Lee. Throughout these questions we’ve gotten your perspective as a clinician, but we also like to ask about your origin story on the podcast — how you got into healthcare, how you got into this intersection of technology and healthcare, and how you came to understand both sides. Our listeners would love to hear more about that.

Dr. Lee: Thanks for asking. Early on in my childhood I thought I wanted to be a doctor. I had older siblings who went into medicine and I saw the gratification and satisfaction they had in their work, so it was an easy path for me when I was thinking about the intersection of science, healthcare, and being able to help patients. That’s how I first got into medicine. I actually thought I was going to be purely a clinician my entire career — that’s what I went into medical school and residency thinking I would do. But along the way, I was fortunate to have mentors who allowed me to think beyond that and exercise my interests outside of direct clinical care. I was always interested in doing things more efficiently using technology and incorporating that into the practice of medicine. Early on in my career at Kaiser Permanente, I was fortunate to be involved with different technology products and projects that led me down a path where I saw the magnitude of how technology could affect healthcare in the present and into the future. When the AI boom happened, I saw that magnified significantly, and that’s why I decided to embark on my work with Nala — an innovative, agile company really improving the lives of clinicians using these tools. I wanted to bring this type of technology to all clinicians because the burden of clerical and administrative tasks hinders our ability to provide the best care possible. If we can have technologies like Nala and other AI-powered tools, I think the healthcare system can not only improve how we deliver care and the quality of care, but also the cost of care — because we’ll be providing care that is more proactive and less reactive, which is better for patients and economically better in the end as well.

Ritu: Thank you for sharing that, Dr. Lee. That’s always very inspiring for our listeners. What you talked about — proactive versus reactive — we’ve been hearing a lot, especially in the context of wearables and the constant stream of information coming in that’s going to change the nature of doctor’s visits. People are already uploading their entire blood reports to ChatGPT and other AI platforms and wanting answers. Medicine is going to change very quickly. We’re almost at the end — it’s always great to hear your insights. Any closing remarks or advice you would have for our listeners, and what are your predictions for the next one to three years?

Dr. Lee: I thoroughly enjoyed the conversation — thank you. As I think about it, at the end of the day AI is just technology. I don’t mean “just” to diminish it, but it is technology, and I’ve always believed that technology in healthcare is really there to improve how we care for our patients. If we do this right, it shouldn’t feel technical — it should feel more human. It should give clinicians time, attention, and presence back. And I think that’s what patients remember, and what clinicians remember as well. At its best, healthcare is human, and I think AI should help us get back there.

Ritu: Great answer. Thank you so much, Dr. Lee. We really enjoyed our conversation. Thank you for being our guest.

Dr. Lee: Thanks so much, Ritu. Appreciate it.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI Will Shape Healthcare Through Access and Affordability

Season 7

Episode 202 - Podcast with Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell -
AI Will Shape Healthcare Through Access and Affordability

The Big Unlock
The Big Unlock
AI Will Shape Healthcare Through Access and Affordability
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In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vision for AI’s role in reshaping care delivery. He argues that telehealth has largely been used as a substitute channel for traditional visits, whereas its true potential lies in redistributing expertise and democratizing access to care at scale.

Dr. Schoenberg sees AI becoming the primary entry point to healthcare, guiding patient journeys through intelligent, cost-driven pathways while working in concert with, rather than replacing, clinical systems. Through his new venture, Aileen AI, Dr. Schoenberg introduces a fundamentally different approach to virtual care: building “staying power” in patients’ lives through deeply personalized, relationship-driven AI interactions, for seniors. By focusing on familiarity, trust, and daily engagement—delivered through simple interfaces like phone calls—Aileen aims to address the growing caregiving gap. Ultimately, he emphasizes that while AI adoption will evolve gradually, its role as a foundational layer in healthcare is inevitable. Take a listen.

This guest appearance was facilitated through conversations initiated at HIMSS.

About Our Guest

Roy is a serial Health-tech entrepreneur. After founding and running both private and public companies, (now into his fourth venture), Roy’s Impact can be easily traced to everything from Tele-ICU to Patient Portals, the introduction of Telehealth and now Ai’s arrival into healthcare. He worked closely with leaders of our largest health systems, national and regional payers, blue chip tech companies, state and federal agencies, policy makers both in Washington and overseas.

After founding and leading Amwell as its CEO to its IPO and a $9B market cap, Roy transitioned to an executive board position so he can focus on his next disruption - a novel model for the use of Ai for caregiving and elder companionship. His groundbreaking ideas in this area have already captured the industry’s imagination as evident in the recent New England Journal of Medicine Catalyst publication. Outside of his entrepreneurial endeavors, Roy chairs the MIT Sloan HSI healthcare advisory board. He is a member of the American Heart Association telehealth board and his hometown Mass General Brigham Patient Safety Research and Practice board.

Previously, Roy served on the board of the American Telemedicine Association, where he was honored with the industry leadership award. He was inducted into the USCF hall of fame, and was repeatedly recognized by Modern Healthcare magazine as one of the 100 Most Influential People in Healthcare. Roy holds an M.D. from The Hebrew University and an M.P.H. from Harvard. He is happiest next to a whiteboard or a microphone, believes in creative provocation, owns over 50 issued US patents and divides his time between Boston and the island of Nantucket with his wife and two children.


Ritu: Hi everyone. My name is Ritu, and I’m the managing partner at Damo Consulting and co-host of the Big Unlock Podcast. A very warm welcome to all our listeners for this next episode of Season Seven. Today we are really excited to welcome back Dr. Schoenberg to our podcast. He’s been on season three, episode 94. He’s the co-founder of Amwell and a pioneer who helped bring telehealth into the mainstream of US healthcare. Under his leadership, Amwell became a foundational platform for health systems and payers navigating the shift to virtual and hybrid care. Dr. Schoenberg is a physician by training and has operated at the intersection of clinical care, technology, and large-scale healthcare transformation. He is now focused on his next venture, Eileen.ai, exploring how AI can further reshape care delivery and decision-making. With that introduction, I’ll hand it over to you, Roy. Thank you so much for joining us today.

Roy: Thank you for having me, and thank you for the very kind introduction. I learned things about myself — this is great.

Ritu: Good to know. It was really good to see you at HIMSS and hear more about Eileen, and I’m sure today we’re going to hear much more since it’s been launched now. But we’ll start with the first question about Amwell. Amwell invested early in building a platform model for virtual care, but many health systems are still struggling to operationalize telehealth beyond siloed use cases. Looking back, what do you think were the biggest mismatches between how you envisioned platform adoption and how health systems actually implemented it? And if you were doing this all over again, what would you do differently to close that gap?

Roy: That’s a good couple of loaded questions. At the very highest level, the notion of delivering care over technology can be looked at in two ways. One, you can look at it as just another channel for the same encounter to take place — over a technological channel. Or you can look at it as more of a switchboard that allows you to completely reshuffle how services are acquired and delivered. Model number one is: I am your doctor, we have a follow-up appointment, and it’s going to be carried out through telehealth rather than in the office. That creates convenience and some level of efficiency, and I think that’s the majority of how health systems are utilizing this technology today. The vision behind it, though, is to give it wings — instead of just executing the same thing through technology, maybe we can democratize the availability of services at a much larger scale. To give you an example, if you happen to live in Boston where I live, cancer care is very available — Dana-Farber, Mass General. But the knowledge of those clinicians could be made available to oncology patients or even primary care physicians in West Texas or North Dakota or other places that don’t have those large cancer centers. If we created the supportive logistical framework to allow skills to flow over technology to the end of the earth, you are rewriting the healthcare experience altogether. Obviously, there’s a lot of muscle memory in healthcare that makes this challenging — health insurance, medical licensure, credentialing, and a variety of other elements that stand in the way of market forces fueling this. I still think it is inevitable. If there’s anything I would say, I think we — like many others — underappreciated how protective the healthcare system is of itself from those kinds of changes. But I think the train is out of the station. Post-COVID, the understanding that healthcare will be redistributed through technology is bigger than ever. So we’re very proud of where we got.

Ritu: You’re absolutely right. COVID normalized virtual health and telehealth, and now with AI we’re really hoping to see this taken to the next level and become truly transformational. Along the same lines, Amwell was built as a platform, but now with AI-native companies emerging, do you think the future still belongs to platforms? Or will it belong to more vertically integrated AI-driven solutions coming into healthcare?

Roy: We used to have conversations about cloud versus server farms fifteen years ago, and that conversation completely disappeared. At this point, nobody in their right mind is going to operate a server farm. I think the conversation about platform versus vertically integrated is also going to become hindsight very quickly, because people are going to care more about how the transition of any one patient takes place between different elements of care. AI will probably become the surrounding technology — the most accessible healthcare interaction you’re going to have, even for follow-up care, will come through AI just because of the economics of it. The magic will be in how AI works in concert with other vertical systems for follow-up care, diagnostics, hospitalization, and so on. There’s a lot of focus right now on whether AI can be a doctor — is it smart enough, does it know enough. The narrative is that if it can be as knowledgeable as a doctor, of course we’ll go to AI because it’s very accessible. But I think that’s a bit of an underestimation of the complexity ahead of us. There’s a lot of sentiment around seeing a doctor in person, and you can trivialize AI by calling it just a chatbot, which doesn’t give any level of reassurance. The groundbreaking event still ahead of us — the one that will dramatically change how healthcare operates with AI — is when payers introduce an insurance product that requires you to interact with AI first if you sign up for it. A little bit like what they tried with HMOs in the eighties, where the PCP was the gatekeeper. That didn’t go well for a lot of different reasons — it was not popular and felt too restrictive. But what they tried to do was control the entry point of a patient into the healthcare system, and if done effectively, potentially control consumption and referrals. The same logic applies to AI. If we can ensure patients first interact with a very knowledgeable technology that is guided by what we know is economical and high quality, we have an opportunity to influence their healthcare journey. But it’s not going to be by convincing patients that AI is better than a doctor. It’s going to be because if they choose the product that requires them to use AI, they will save a lot of money. It may sound cynical, but cost is a very powerful influence on how people consume healthcare. My sense is that it won’t be black and white — it’ll be a product that says the more you use AI, the more you save. A shared savings model. And it will have to be designed smartly, saying there is AI, and if the sky falls you can break the glass and see a clinician, then return to AI. But my bet is that that is how AI will begin to dominate our experience as patients.

Ritu: That’s a great perspective, and we do see it heading in that direction. With ChatGPT and OpenAI, health is now one of the most queried topics — I think 30 to 40% of all queries on ChatGPT right now are about health. And they’re not necessarily doctor-related questions; they’re questions from people who want to be prepared for the doctor’s appointment, asking the chatbot what they should ask their doctor. It’s really interesting that patients are going there first, and only in extreme cases seeking access to a clinician. If AI can handle everything else, then why not?

Roy: That’s exactly right.

Ritu: Okay, great. Now we can start talking about Eileen, which we were so curious about — such an interesting product. What insight or frustration from your experience at Amwell led directly to founding Eileen? And what is the problem you’re solving that is so fundamentally different from telehealth? Because this is also remote and also involves talking to patients virtually, but what’s the biggest mindset shift, and can you tell us more about Eileen?

Roy: The motivation to build Eileen had nothing to do with Amwell or telehealth directly, but there is a corollary. There’s a similarity in the challenge: you need to socialize and get people comfortable experiencing a certain dimension of their healthcare through technology. With telehealth, the place of service changed and the mode of interaction changed. With Eileen, it’s the visceral connection that you need in healthcare — that connection is now going to be furnished by AI instead of by people. It all started with a very interesting academic conversation about the role of AI in healthcare. There was a big group at the table talking about how it’s going to change the way information is analyzed, packaged, and communicated — reminders, scribing, all the things we know AI can do. To keep the dinner interesting, I took the contrarian approach and said I think AI has a role in changing the interface between technology and people in healthcare. Specifically, the most challenged population in terms of healthcare and technology are seniors. There’s clearly a need there because the reality of caregiving is very daunting. We have more and more seniors as a part of the population — doubling and tripling in size over the next decade — and at the same time the number of caregivers available to them is going in the wrong direction. People don’t want to do senior care. It doesn’t pay much and it’s emotionally and physically draining. So we have a real problem in caregiving, and the thinking is maybe AI can step into that growing void and become supportive to seniors. Now that part alone isn’t terrifically creative, because there’s a whole world called age tech designed to do exactly that — thousands of applications, all with their hearts in the right place, trying to support senior self-sufficiency. They come in wonderful shapes and sizes: chatbots, talking orbs, talking pill boxes. All wonderful designs. But the general sentiment is that because of the love-hate relationship between seniors and technology, most of these technologies die on the vine. They either don’t create adoption or they don’t create staying power — they create fatigue and eventually just never get utilized. So the nut hasn’t been cracked. Eileen steps in and says something really simple: if technology is to have a regular, influential role in the life of a senior, then maybe our first order of business is not to tell them what to do, but to establish a regular presence in their daily lives — something that is going to be sought after, something that is going to be part of their regular daily routine that they would want to interact with. If we are successful in creating technology that has that staying power in their daily lives, then through that technology we can communicate medication reminders, dietary reminders, and all the rest. But the trick is that staying power in the life of someone doesn’t come from reciting a medication list. Staying power — putting technology aside — comes from people that know you. Familiarity, intimacy, the ability to talk about your kids and grandkids, to talk about where you come from and your joys and frustrations and relationships and likes and dislikes. So, the goal is: how do you get AI to become that intimate? That’s actually a much bigger technological challenge than people give it credit for. People talk to ChatGPT and think, oh, it feels like a casual conversation, like I’m talking to someone. But for that technology to actually understand where you come from, to know the names of your grandkids, to know whether your dog got into trouble with the neighbor — that requires a completely different level of orchestration. First of all, because it’s not written anywhere. AI is really wonderful when you can feed it a lot of information, but nobody wrote the book about my dad. If AI is supposed to know everything about my dad, there’s really nothing for it to acquire that information from. And secondly, with seniors specifically, AI is designed to respond to prompts. Even the term prompt engineering tells you about the choreography — we write something in, AI comes back. We know that’s not going to work with seniors, because if we wait for seniors to prompt, we’re going to be waiting a very long time. So the whole way AI typically operates doesn’t work here. Eileen was designed to address those challenges — to become a very intimate, very engaging, knowledgeable partner in the life of the senior. One that initiates the relationship itself, doesn’t wait for the senior to download an app or log in or pair with the internet. It uses the phone to call them, the way their kids and family are supposed to. And the magic that happens during the call is that it doesn’t talk about healthcare — it talks and remembers and carries a conversation about what the senior wants to talk about, about the things that excite them or that they spend time on. It has intimate knowledge and a deep commitment to learning what they are interested in and curious about, what makes them laugh, and what they can’t tell anybody else and want to talk about. These are the things Eileen focuses on, because its purpose is to have staying power — regular, daily staying power in their lives. And then it is humble enough to understand that if it achieves that, it’s just a cog in the wheel — a mouthpiece to other technologies that can handle medication reminders, symptom monitoring, anxiety and depression tracking, and all the other things healthcare technology knows how to do. But this one creates the staying power. That’s what Eileen is all about.

Ritu: I remember when you told us about it earlier, I was struck by that very different approach — it’s not a wearable, not an app, not some high-tech device. It’s just a regular phone call, like you would receive from anyone. I thought of my mom and how she interacts with technology, and yes — she loves to get phone calls. That’s something she would actually do. It really makes a lot of sense for the senior age group you’re targeting.

Roy: We think about the simplicity of getting a phone call, but there’s also an eye on how you make this technology available to people. If we’d come up with something that requires installation, internet setup, or a technological learning curve, both the economics and the availability of the product would have completely changed. What we want is to reach a position where if you’re a family increasingly struggling with the heavy lift of being there for your parents who may live far away, and you want something to share that burden with you, we can offer the ability to activate Eileen today and she would start calling tomorrow morning. Anything that doesn’t use the phone — that doesn’t use a staple the senior is already familiar with — would require a completely different kind of orchestration, a completely different cost structure, and would make it significantly less useful to the people who need it most. There’s a lot of thinking behind why we ended up with this seeming contradiction where the backend of Eileen is rocket-science AI — really science fiction kind of AI — whereas the front end of Eileen doesn’t even need Wi-Fi.

Ritu: That’s a really interesting way to think about it. And I remember you also mentioned family groups — that Eileen will actually call family members to learn more about the senior. Is that right?

Roy: If the goalposts here are so much about intimacy and knowing the senior’s reality, and we’ve acknowledged that’s not documented anywhere, then one of the wonderful things about AI is we can say: the people who know the senior are the son and daughter, sometimes the grandkids, maybe a neighbor, maybe a spouse. The way Eileen starts serving a senior is by autonomously reaching out to those people who are close to that senior and carrying out regular conversations with them over the phone to learn about that senior’s reality. It has a very nonchalant, disarming way of doing it — you don’t have to schedule meetings or fill out forms. It just calls and says, when you have a minute, let’s chat. Then it begins building an understanding of the senior’s reality, and once it crosses a certain threshold where it has enough context, only then does it begin calling the senior directly on a regular basis. And at the end of the day, it reaches back out to the son and daughter and says, hey, I spoke to your dad a couple of times today — he was really upset about something, or he’s grumpy but that’s his usual way and everything is fine. We’re at the very early stages of this, but the framework and the approach — this very different mixture of technologies coming together on the different sides of Eileen — seems to be attractive, interesting, and plausible. And as I mentioned at the very beginning, we have to go there, because we are facing a caregiving meltdown. We’ve got to find a way for technology to help us.

Ritu: We usually start with an origin story, but we didn’t do that today. With a few minutes left, I’d love to ask what brought you into healthcare, and with Eileen I can see you really resonate with this topic. How did you get into this intersection of healthcare and technology?

Roy: I used to be a clinician. I did the whole training and thought for a long time that being a practicing clinician was the way I’d go. But I was actually dabbling with technology since I was twelve years old. I stayed home from school — I had pneumonia or something — and my dad got me a Commodore 64, which people don’t even remember existed. I think it had 5K of memory. So since then I’ve been programming and building things. After training and becoming a physician and practicing, what really interested me about technology is that if you build it right, you have the ability to change the lives of people much more widely than even a very successful practice. And the other piece is that healthcare today requires clinicians to be highly specialized, doing the same thing over and over and getting really good at it. But the mission of healthcare — advancing the wellbeing of people — becomes very siloed and myopic when you only do one procedure extremely well every single day. Technology became a different pathway to realizing the same mission: to continually rethink how we can advance the wellbeing of people and make the healthcare experience less painful. Technology today just has a bigger wingspan than some standards of practice. I’m not saying it’s better or worse — I think we need both. But I found my passion in health tech, and it’s the gift that keeps on giving.

Ritu: We’re almost at the end, Dr. Schoenberg. It’s been wonderful chatting with you. Do you have any closing thoughts or predictions for where you see AI going within the next year?

Roy: I’ll just say this: I think we’re very young in this. We get very excited about what AI can do, and I’m pretty sure that, not unlike other technologies, there’s going to be a long period of maturation — mistakes will happen and there will be things we’ll have to worry about. But the entrance of AI as a surrounding system for our healthcare experience is an inevitability. If we know we’re going to get there, you’ve got to put one foot in front of the other and start walking. That’s exactly what we’re doing. It’ll take a village — we need the brainpower and creativity of many people. But we couldn’t be more excited. I think we’re going to change the world no less than what telehealth did.

Ritu: Awesome. Thank you so much, Dr. Schoenberg. It’s been a pleasure having you on the podcast.

Roy: Terrific. Thank you so much for having me.

 

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

 

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

From Guidelines to Outcomes: What Autonomous AI Can Deliver in Healthcare Today

Insights by Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health

“Healthcare doesn’t need new technology. We need to implement what we already know works.”

That’s the underlying message Dr. Eric Stecker returns to throughout this episode of The Big Unlock. And it’s a striking perspective to hear from someone who sits at the intersection of clinical practice, population health, and AI product development.

Dr. Stecker is a practicing cardiologist and professor of medicine at Oregon Health & Science University, and he co-founded Insight Health to apply AI in ways that measurably improve real-world outcomes. He’s also spent years inside the guideline and quality ecosystem of cardiology, most notably as Chair of the American College of Cardiology’s Science and Quality Committee, which shapes national cardiology practice guidelines and policy documents. In other words, he’s not arguing from theory. He’s arguing from a place of deep familiarity with what evidence already supports and frustration that the U.S. healthcare system still struggles to carry that evidence into daily practice at scale.

The episode begins with a timely setup. Coming off conferences where “AI was everywhere,” the hosts ask about wearables and continuous data streams, and whether we’re heading toward continuous cardiac care. Dr. Stecker agrees that the future is exciting. But he draws a line between what is still evolving evidence and what is already proven, and he argues that autonomous AI can deliver enormous clinical value today without waiting for fully autonomous diagnostic AI.

Listen to the full conversation

Autonomous action versus autonomous decision-making: a critical distinction

One of the most useful contributions Dr. Stecker makes is a simple conceptual distinction that clarifies much of the market noise.

He divides autonomous AI into two categories:

  • Autonomous action (AI taking action on established protocols and workflows)
  • Autonomous decision-making (AI making clinical decisions, diagnoses, or orders without a human in the loop)

These two ideas are often conflated. Dr. Stecker insists they shouldn’t be.

Autonomous decision-making is the “hard future,” and he’s clear about why; it requires significant technical maturity, safety assurance layers, deep clinical validation, regulatory readiness, and, just as important, trust from both healthcare workers and patients. It’s coming. It’s needed. But it’s difficult.

The bigger mistake, he argues, is waiting for that future while ignoring what autonomous action can do right now.

This is where he makes a point that feels both obvious and urgent. We already have decades of high-quality evidence showing how to prevent cardiovascular events, yet we still fail at the mundane steps of implementation.

He uses cholesterol therapy as a straightforward example. Statins are not new. The evidence base is vast. Yet health systems still struggle to reliably identify eligible patients, start therapy, and support adherence over time. The result is preventable harm: heart attacks, strokes, and deaths that occur not because we lack knowledge, but because implementation breaks down.

In his framing, autonomous action is the opportunity to close that implementation gap at scale today.

And he offers a memorable “why now” scenario: what if every patient starting a new medication received consistent follow-up? What if someone checked whether they filled the prescription, whether they were having side effects, and whether they had questions, then checked in again at the interval the patient chose?

That doesn’t require futuristic diagnostic autonomy. It requires operational execution at scale.

And that, he argues, is exactly what autonomous agents can provide.


Clinician involvement is the difference between signal and noise.

If autonomous action is the promise, the risk is obvious, says Dr. Stecker, “more AI can also mean more burden.”

The hosts raised the signal-to-noise problem directly, asking about alerts, risk scores, predictions, summaries, and data streams that can overwhelm clinicians and patients. Dr. Stecker doesn’t dismiss those concerns. He agrees this is real and points out that medicine has seen it before.

He recalls the early EHR era, when alerts proliferated, and clinicians learned to click through them just to get through the day. Alert fatigue is well-documented. The danger now is that healthcare repeats that lesson in the AI era: flooding workflows with AI-generated documentation or repeated check-ins that create cognitive load rather than relief.

This is where Dr. Stecker makes a strong operational point: meaningful clinician involvement is not optional.

Not clinician involvement as advisory branding. Not “a chief medical officer who joins two meetings a month.” He’s talking about integrating experienced, practicing clinicians into product development and implementation so that the system is designed from the beginning to escalate only what matters and to avoid generating unnecessary documentation.

He gives a practical example. If an oncology practice checks in weekly with patients and generates a long summary every time, pushing it into the HER, that means someone must read it, interpret it, and decide what to do. Done poorly, the AI “help” becomes a new inbox burden.

The fix, in his view, is workflow design:

  • escalate only meaningful medical flags
  • keep routine information from becoming unnecessary documentation
  • offer dashboards or condensed summaries rather than long notes
  • design protocols that define what “needs attention” vs what is “normal.”

This is the heart of his execution argument: AI must be built to reduce the burden, not shift it.

And it reinforces his broader theme: if you leave development to people who haven’t practiced medicine or to teams that don’t understand real clinical workflows, signal-to-noise failures are inevitable.


From cardiology to population health: meeting patients where they are

The episode also reveals why Dr. Stecker is unusually focused on population health outcomes.

He describes how he came to cardiology through physiology and then electrophysiology. But he also brings an engineering-oriented mindset to medicine, influenced by his father, an engineer, and by his early exposure to databases and analytics. That “systems” orientation shows up repeatedly: he’s interested not just in what’s true clinically, but in what can be operationalized across large populations.

When asked how cardiology changes in an AI world, he shares a hopeful view: “Clinicians and patients should not have to ‘evolve too much.” The technology should fit around the current experience and dramatically improve it, unlike many past tools that felt imposed on clinicians.

As he does throughout the podcast, he gives a concrete example, autonomous agents that reach out before visits to gather medical history and symptom details, even at 2:00 a.m. if a patient is a shift worker, so that patients don’t spend precious visit time answering basic intake questions. This is a key pattern he returns to: meeting the patients where they are, on their time, in their context, while improving readiness and efficiency for the clinical encounter.

He then expands into what his team calls different interaction modalities:

  • voice-only agents (phone calls)
  • text-based interactions
  • “visual voice” experiences that blend voice with on-screen guidance and embedded media

The point is accessibility and engagement. If an AI agent can show a short instructional video to help a patient place a cardiac monitor correctly without requiring them to search online or call a help line, you reduce friction and improve adherence.

This matters because the value of autonomous action isn’t only clinical. It’s behavioral. Patients are more likely to engage when the experience is simple and supportive.


The Takeaway

Dr. Eric Stecker’s message is refreshingly direct; healthcare doesn’t need to wait for fully autonomous diagnostic AI to start saving lives at scale. We already have decades of evidence for preventing cardiovascular disease and other high-burden conditions, but we repeatedly fail to implement these interventions, including identifying eligible patients, initiating proven therapies, and supporting adherence over time. His key distinction is that autonomous action is both safe and powerful today when it’s grounded in established protocols and designed with real clinician involvement to avoid alert fatigue, documentation overload, and signal-to-noise failures. In his view, the organizations that lead won’t be the ones chasing the most futuristic promises first. They’ll be the ones who use autonomous agents to turn evidence into consistent action, building trust with healthcare workers and patients now, while responsibly advancing toward autonomous decision-making tomorrow.

Sitting at the intersection of guideline-level evidence, practicing cardiology, and real-world AI execution, Dr. Stecker’s unique insights are especially valuable:

  • Autonomous action and autonomous decision-making are different, and the fastest path to impact is autonomous action on established protocols.
  • The biggest “AI opportunity” in cardiovascular care is implementation: statins, hypertension control, and adherence support can prevent massive harm today.
  • Trust is a prerequisite for autonomy. Patients and healthcare workers must see AI as reliable, safe, and helpful before decision-making autonomy can scale.
  • Clinicians must be integrated into development and implementation to prevent alert fatigue, cognitive overload, and documentation bloat.
  • AI agents can meet patients where they are, collecting pre-visit history, guiding setup with visual support, and improving engagement without adding friction.
  • Population health impact comes from operationalizing prevention: identifying care gaps, educating patients, capturing preferences, and scheduling follow-through at scale.

AI Leadership Starts with a Simplified, Integrated Tech Stack

Season 7

Episode 201 - Podcast with Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer,
Nebraska Medicine - AI Leadership Starts with a Simplified, Integrated Tech Stack

The Big Unlock
The Big Unlock
AI Leadership Starts with a Simplified, Integrated Tech Stack
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In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case for sustainable digital transformation in healthcare. Sustainable digital transformation requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.

Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.

Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.

About Our Guest

Michael Hasselberg, PhD, RN, PMHNP-BC, is the chief transformation and digital officer for Nebraska Medicine, where he leads information technology, the strategy enablement office, and the innovation team. In this role, he drives enterprise efforts to modernize care delivery and accelerate digital transformation, aligning technology, clinical operations and strategic growth initiatives. His work focuses on scaling solutions that improve patient outcomes, enhance clinician experience and strengthen health system performance. Dr. Hasselberg is also a professor of family medicine in the University of Nebraska Medical Center’s College of Medicine and volunteer professor in the College of Nursing.

Before joining Nebraska Medicine, Dr. Hasselberg spent more than two decades at the University of Rochester (UR) in New York where he held faculty appointments in psychiatry, nursing, and data science. His last role was serving as UR Medicine’s first chief digital health officer and co-director of the UR Health Lab. Dr. Hasselberg earned his Bachelor of Science in nursing at Binghamton University, Master's degree as a psychiatric mental health nurse practitioner from UR and then went on to earn a PhD degree in health practice research from UR.

His expertise expands health and technology as a Robert Wood Johnson Foundation Clinical Scholar Fellow and committee member for the National Academies Standing Committee on Primary Care. He has also been an advisor on digital transformation to government agencies, industry, venture, and health systems across the country.


Ritu: Hello listeners, a very warm welcome to the Big Unlock Podcast. My name is Ritu, and I’m the managing partner at Damo Consulting and co-host of the Big Unlock Podcast along with Rohit. We are extending a very warm welcome today to Dr. Michael Hasselberg. He’s been on the Big Unlock Podcast before — in 2022, season four, episode 138.

Welcome back. Dr. Hasselberg is the Chief Transformation and Digital Officer at Nebraska Medicine, where he is leading enterprise-wide efforts to modernize care delivery through digital innovation and operational transformation. He has a background in emergency medicine, public health, and informatics, and brings a uniquely systems-oriented perspective to scaling technology in complex health environments. Today he’s joining us on the Big Unlock Podcast and we are really excited to have this conversation. With that I’ll give it to Rohit for his introduction, and then it’s all yours, Dr. Hasselberg. Welcome once again.

Rohit: Thank you. Welcome, Michael, to the podcast — really nice to have you again. I am CEO of Damo and co-host of the Big Unlock Podcast. Short intro from our side; over to you.

Michael: It’s great to be back, and a lot has happened since we last talked in 2022, so I’m excited to dive in with both of you.

Ritu: Almost seems like a different era. Seriously. So, Dr. Hasselberg, we always love to start with an origin story because our listeners like to hear unique stories about how people got into healthcare and how they got to where they are today. If you’d like to start with that, we’d love to hear your story.

Michael: Sure. First and foremost, I’m a nurse, and very proud of being a nurse. I went on to become a psychiatric nurse practitioner very early in the psychiatric nurse practitioner movement. When I graduated, there weren’t actually any jobs for psych NPs in the city of Rochester. So, my first job as a nurse practitioner was about an hour and a half to two hours away from Rochester, where I drove every day to a very rural community in New York State where I was the only psychiatric prescriber for about six counties.

I managed the outpatient psychopharmacology clinic and the jails and the nursing homes. It was a pretty transformative experience that made me very passionate about serving vulnerable communities. The patients I served were so grateful that I was willing to drive that far every day to provide care. That experience became my underlying “why” for the rest of my career — how can we find more efficient ways to get healthcare out to communities that weren’t getting the care they deserved.

From there I finished a traditional research PhD, and after that I was tasked with developing a telehealth infrastructure for psychiatry at the University of Rochester. This was well before telehealth was widely reimbursed in the States. We built a very large telehealth infrastructure across New York State, and eventually reached a point where I couldn’t grow it further because I couldn’t graduate clinicians fast enough to take on more patients on the other end.

That’s when I really leaned into innovation. I started thinking about whether we could use technology without needing a clinician on the other end to deliver care. I got into the world of mobile apps and started working with the engineering school and computer science department to develop mobile apps for behavioral health. Then I moved from mobile apps into virtual reality when the first Oculus Quest headset came out — affordable, powerful, and untethered — and started developing mindfulness and meditation applications for VR headsets.

By that point I had different layers of digital interventions: apps, telehealth, VR headsets, and in-person care. I got really interested in data science and started thinking about whether I could use big data to risk-stratify patients to the right level of care at the right time in the right place. That drew me into machine learning and data science about seven or eight years ago.

Then COVID hit and every health system had to go digital overnight. I was put into a new position as Chief Digital Health Officer at Rochester to lead that digital transformation strategy. About two to three years ago, when the world was introduced to generative AI, our innovation team at Rochester got early access to some of those foundation models in a secured, private way. I was pretty blown away by their power. Around that time — 2022, when we last spoke — I was making comments in national forums that with the advent of generative AI, it had never been easier for health systems to develop their own AI tools in-house to solve their own problems, rather than relying entirely on vendors.

That’s when I got to meet Dr. Michael Ash, who was serving as the Chief Transformation Officer at Nebraska Medicine. Dr. Ash is a very innovative, entrepreneurial, visionary thought leader from a technology standpoint. We started exchanging ideas, and he was eventually named incoming President and CEO of Nebraska Medicine. He invited me to Omaha as a visiting professor to see the health system, and I fell in love with Nebraska, Omaha, and the organization. It was a very hard decision because I love Rochester through and through, but I took the leap to join Nebraska Medicine in Dr. Ash’s former role as Chief Transformation and Digital Officer.

Ritu: Wow, that’s a great recounting of the entire story — thank you. Really interesting for our listeners to hear as well. One thing I picked up on is that your title emphasizes transformation, not just Chief Digital Officer. What’s the difference, and where do most health systems fall short when trying to bridge that gap?

Michael: One of the things that excited me about Nebraska Medicine is that they are, I would argue, more mature and out ahead in terms of their leadership structure. They are very nimble in regards to the number of chiefs who report directly to the CEO and president. There are six chiefs — the Chief Transformation and Digital Officer being one — along with the Chief Operating Officer, Chief Financial Officer, Chief Medical Officer, Chief Nursing Officer, and then a combined Chief Legal and People Officer.

What excited me about Nebraska to do transformation at scale is that it goes well beyond just technology. In my role I’m accountable for three main verticals. First, IT — the Chief Information Officer reports up to me. Second, our innovation and venture arm, which we can dig into deeper if listeners are interested, because we’re doing some really cool things there. And third, the strategy office — we have a VP of Strategy Enablement and an entire strategy office that looks at markets, guides acquisitions, and evaluates joint ventures.

The strategy office is also where our AI efforts and engineers sit. Having strategy, innovation, and IT all underneath essentially a transformation office means we’ve got the right ingredients to do transformational work at scale. That’s what’s really exciting for me and why I took the leap to Nebraska. I think we’re very well positioned structurally to not only improve the lives of all Nebraskans, but to become the gold standard for the rest of the country on what the future of healthcare looks like.

Ritu: That’s a really good answer. Having those three things — IT, innovation, and strategy — reporting into you is directly related to the next question. A recurring issue we hear from Chief AI Officers and Chief Digital Officers is a lack of operational ownership for digital initiatives, which leads to most pilots failing or fading into obscurity. Having those three arms under you and being fully responsible must be doing a lot to ensure the success of these initiatives. We’d love to hear more about the venture arm — what’s your approach to developing new technologies and incubating ideas?

Michael: One of the really exciting things is that we already have a commitment from the health system, the university, the state, and our philanthropists to build a $2.2 billion Hospital of the Future. It’s already underway — we’ve got a hole in the ground, construction has started, and the doors will open on our main campus in about five years. We know that with healthcare and technology changing so quickly, it’s really hard to answer the question: what will the hospital room of the future look like five years from now?

To prepare ourselves to answer that question, we’ve already made significant investments in our innovation ecosystem — hundreds of millions of dollars into our Edge District. The Edge District is focused on two things: what I’d call inside-out innovation, where our researchers are developing new intellectual property that we look to potentially commercialize and spin out as startups; and outside-in, where local startups that want to get into healthcare and understand healthcare problems can get involved.

On the university side, we’ve also made significant investments in simulation and education for our future leaders. We have a program called iEXCEL, which I believe is one of the largest, if not the largest, simulation centers in the entire country. They’re using very frontier technology — we’re leaning heavily into holograms. We actually have a hologram theater where we can create holograms nearly the size of a room of hearts and organs that students can interact with as they’re learning anatomy and surgery. Of course, we also have simulation rooms and surgical simulation suites in that building.

But the really unique and exciting element is our Innovation Design Unit and Bridge Program, which sits inside Nebraska Medicine itself. We’ve built a 17-bed med-surg unit that can scale up to an ICU if needed, and it has all the bells and whistles of technology. The unit itself is modular and all glass — touch the glass and it frosts over. When we hire staff to work in the Innovation Design Unit, we look at their behavioral profiles during interviews: are they agile, knowing that how they deliver care and the technology they use is going to be constantly changing and iterating?

There’s literally a bridge off that unit to our Bridge Program — a small mockup of the unit where our engineers, data scientists, and clinicians bring in vendors or build new technology, test it in that environment, and then nurses and physicians can come over, play with it, and test it before we bring it live with patients in the Innovation Design Unit. The learnings from those technologies are informing exactly what we’re going to put into Project Health, our new Hospital of the Future. I’ve been to innovation programs around the country at some of the leading health systems, and I have never seen anything like this.

Ritu: Amazing. So, these holograms are like digital twins?

Michael: Yes, exactly. It sits on the university side, and essentially as we’re training students, we can input radiology images and the system creates a hologram of that organ from the image. Students can interact with the hologram as they’re learning anatomy and how to perform surgery.

The other exciting thing is that Nebraska is a rural state and the University of Nebraska has four campuses, one of which is in a rural part of the state where a new medical school cohort is starting up. The university has worked hard on how to transmit these holograms remotely out to that campus, so faculty specialists in Omaha can continue to support and teach those students at a distance using this forward-thinking technology. Really special and unique — and it’s what I love about being part of an academic health system, really partnering with the university side to educate our future clinicians so they’re ready to function in a hospital of the future that is digitally enabled and AI-augmented.

Rohit: With so much innovation going on, how do you prioritize and allocate resources? And if you’d like to share any success stories — and maybe some failures from a learning perspective as well?

Michael: The maturity of our structure really drives this. We have purposely placed AI — specifically our AI engineers, data analytics, and data scientists — in our strategy office, which keeps the projects we take on aligned with the most important priorities of the health system. Starting from our board metrics down to what we call our Delta projects, and then into our OKR projects.

When a new use case gets submitted, we have a very rigorous evaluation process, and where a proposal scores most points is strategic alignment to our top priorities. Within the strategy office we have a team of process engineers who, when a use case is submitted, deeply examine what problem is trying to be solved and what workflows are involved. The process engineers work closely with our enterprise architects and solution architects in IT to ask: do we already have a technology on our stack that could address this problem? If not, we work through the build-versus-buy question.

I’d argue we are more of a build shop, and that hasn’t always been the case in healthcare. We build about one new generative AI tool per month in-house. We now have 28 tools we’ve built ourselves, deployed at scale — and those AI use cases, which are aligned with our biggest health system priorities, each get what we call a Delta team. The Delta team includes operators, clinicians, informaticists, and technologists. We make sure that from build through deployment, the initiative is properly resourced to be successful and to scale. Once it’s scaled and running, the Delta team moves to the next project, and the tool is maintained as an operational program within the health system.

We’ve had a ton of success focusing on back-office work: throughput, clinical capacity. We’ve built AI tools that identify which patients in our hospital are ready for discharge and automate notifications to nurses — “this patient is ready, here are the orders needed to move them to the discharge lounge and out of the hospital.” Very similar tools around transfers: identifying which patients at rural hospitals across the state are appropriate to transfer to us, and when a patient is with us, identifying when they’re ready to transfer back. Just through automating capacity management, we’ve created over 30 net-new beds in our hospital — not by building new beds, but by automating the processes.

We’ve also automated a lot of scheduling and surgical optimization, getting the right patients in to see our surgeons at the right time. In the revenue cycle we’ve had a lot of success automating denials management, prior authorizations, and registry reporting — freeing up nurses from manually extracting data to submit to registries so the AI can do that extraction instead.

An example of something that started with significant resistance: a faculty member — a brilliant heart surgeon — went to a conference, met with an AI vendor, and came back convinced he needed their specific tool to help identify structural heart defects to get the right patients to him more efficiently. He was adamant: “The vendor says it’s plug-and-play, fully integrated into the EHR, and I needed it yesterday.” I had to spend a lot of time with him to take a step back and ask: what is the problem you’re actually trying to solve?

Once we fully understood that, I told him we have tools in-house and a data science team that I believed could not only build the same solution, but build it better because it would be personalized to his workflow. He was very hesitant and said, “I’ve heard this before — I don’t have six months to a year for you to build something.” We got past that. We were able to build a solution in less than a month, and he and his service line are very happy because it not only solves his problem, it’s tailored exactly to his workflow.

Ritu: Those are really good examples. We were bracing for the usual ambient documentation and scribe story, so it’s nice to hear about different applications.

Michael: Something people don’t know about Nebraska: when I think of the two most transformative technologies in healthcare to date, on the patient side no one would question that telemedicine has been the most transformative. And Nebraska Medicine was the birthplace of telemedicine — it started here in the Department of Psychiatry, in partnership with the Bell Telephone Company, in the 1950s. Most people don’t know that.

On the provider side, no question — ambient documentation is the most transformative technology. We were the first digital scribe pilot site in the country, in partnership with Nuance and Rush in Chicago, co-developing that technology. The two most transformative technologies in healthcare, and Nebraska was at the forefront of both. I could absolutely talk about our successes with ambient documentation, but I did want to highlight that we were one of the first, working with Nuance years ago as they were developing that technology.

Ritu: Great information — the listeners will love hearing that. We’re almost at the end; time has flown by. We’d love to hear what you see coming down the pipeline in the next one to two years that could be as transformative as ambient documentation.

Michael: I can tell you, and this may not be the sexy answer listeners are hoping for: the biggest transformative project I’ve kicked off as the new Chief Transformation Officer at Nebraska is actually a cleanup project. I’ve just launched application rationalization, and it is not an IT-driven project — it’s a health system strategic initiative.

Over the years, partly as a result of our innovative culture, we’ve had significant application sprawl. Our technology stack is very, very complex. My argument is that if we really want to continue to be leaders in AI and innovation, we have to simplify our tech stack. It will create more standardized workflows across the system, and it will free up my technologists, informaticists, and innovators — who right now are spread really thin managing so many applications.

We’re very excited, and I believe we’re going to be able to cut two-thirds of the applications on our stack over the next couple of years. That will create more efficiencies, unlock more innovation, and set us up even better from a data enablement standpoint to continue leaning into AI. Not the sexy answer, but it’s like spring cleaning — and we’ve got a lot of it to do.

Rohit: I’d add that it’s also an opportunity to infuse the remaining applications with more AI.

Michael: A hundred percent. We’re going to lean into our core applications and their functionality, and every vendor right now is introducing AI capabilities. I want to lean into my core platforms, and to do that I’ve got to remove the noise. This is a health system-level strategy, not an IT-driven initiative. We’ve already been able to identify and retire several applications, so we’re well underway.

Ritu: We’re almost at the end of the podcast. I’m sure listeners have a lot to unpack, and we’ve learned a lot of new and interesting things about Nebraska as well. Thank you so much for sharing, Dr. Hasselberg, and thank you once again for being on our podcast.

Michael: I loved it — this was a lot of fun. Hopefully you’ll invite me back in about four years, right around the time we’re opening our Hospital of the Future. Technology will have changed quite a bit by then.

Ritu: That sounds great — we’ll definitely be there for that. Thank you so much for being on our podcast.

Michael: Thank you. Alright, have a great one.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Escaping Pilot Purgatory: How Healthcare Leaders Can Scale What Matters

Insights by Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital on The Big Unlock podcast

“At TGH, we don’t do pilots.” That line, which was delivered with equal parts conviction and practicality, sets the tone for this episode of The Big Unlock. Rachel Feinman’s point isn’t that Tampa General Hospital flips a switch and rolls everything out systemwide overnight. It’s that they refuse to live in what she calls “endless pilots,” where momentum dies slowly and “testing” becomes a polite way to avoid committing.

Rachel brings a distinctive lens to this conversation because her path into healthcare innovation didn’t start in the usual place. She began as an M&A and business lawyer and found herself frustrated by how quickly strategic conversations ended right when the most interesting operational problem-solving began. She wanted to be in the room where strategy, execution, and value creation were actually happening, not just documenting it after the fact. That mindset, combined with deep involvement in the startup ecosystem, eventually led her to help create what is now TGH Ventures, Tampa General’s innovation, investment, and commercialization arm, translating a CEO’s vision into a structured operating model.

In other words, Rachel isn’t describing innovation as a slogan. She’s describing it as an execution system, one built to move quickly, measure clearly, and scale outcomes, not just ideas.

Escaping “pilot purgatory” starts with a mandate, not a mood

The phrase “pilot purgatory” shows up early in the conversation, and Rachel doesn’t dance around it. She describes a very specific reason Tampa General took a hard stance: pilots often become “a slow no,” or a symptom of misalignment and inability to prove results.

The mandate at Tampa General came from CEO John Couris after frustration with the way pilots can drag on without delivering meaningful operational change. Rachel is careful to clarify that this isn’t about recklessness. It’s about discipline. The organization still starts in a focused place, with a defined problem and an approach designed to prove impact quickly. But the intent is different.

They start with a thesis.

They identify the right partner and solution.

They begin in a setting where results can be measured quickly.

And if the solution performs by driving the outcomes they expect, they scale fast.

For Rachel, this is the key; the “pilot” is not the goal. It is the smallest version of a scaling strategy. If it works, they don’t leave it in limbo. If it doesn’t, they stop and move on.

This stance is important because it reframes the most common failure mode in healthcare innovation: treating experimentation as a destination instead of a step in an outcomes-driven path.

Rachel’s insistence on a thesis-first approach also solves another chronic problem: innovation that chases “the next shiny object” instead of measurable needs. A thesis forces specificity. What outcome are we driving? Where will we start? How will we measure? What would success look like, and how quickly should we see signals?

This is how organizations avoid building impressive “proofs of concept” that never integrate into real operations.


Moving fast without compromising safety: “go slow to go fast”

One of the most valuable parts of the episode is how Rachel resolves a tension every health system leader recognizes.

On one side: “fail fast,” experiment, iterate.

On the other hand, healthcare’s tolerance for risk, especially in clinical settings, is low, and for good reason.

Rachel doesn’t pretend those forces magically align. She explains that the reason healthcare hasn’t moved as quickly historically is that when you’re talking about patient care and safety, failures can have serious consequences. “Fails around safety are not okay,” she says, and that becomes the grounding principle.

So how does a system move faster without compromising safety?

Her answer is to separate domains and apply the right speed to the right work.

She describes an enormous opportunity to innovate in the administrative, operational, and logistics layers of healthcare, well before you get into direct clinical decision-making. She even frames health systems as “one giant logistics company,” coordinating people, schedules, resources, and information across complicated care protocols. In those areas, moving fast is not only possible, but it’s also necessary. Scheduling efficiency, care coordination, and non-clinical process redesign can produce a meaningful impact quickly and safely.

When the innovation touches clinical care, the approach changes.

That’s where her “go slow to go fast” philosophy comes in.

The idea is to go slow at the beginning to set the right guardrails. Put the right governance in place. Get the right people around the table early, such as clinical leaders, safety stakeholders, compliance, and operations, so you don’t spend months later stuck in “what if” loops. It is imperative to do the careful work upfront, deliberately, while accelerating as quickly as possible, in a meaningful way, to the end goal.

Once governance, safety, and guardrails are clear, you can move faster with confidence. You’re not skipping safety, you’re engineering for it, out of the starting gate. This mindset is a direct antidote to a common problem: innovation teams doing great work, only to hit a late-stage wall of approvals and concerns. Rachel is essentially describing a system that front-loads alignment, so execution doesn’t stall later.


The innovation engine: partnerships, ventures, and proof of value

Rachel’s role spans innovation, ventures, and digital solutions, and she explains how TGH Ventures operates with a dual focus that many systems struggle to balance.

Yes, there is an investment strategy. Financial diligence matters. The organization wants confidence in the likelihood of a solid financial return on venture investments.

But her emphasis is clear: strategy comes first.

TGH Ventures evaluates whether a company advances Tampa General’s system strategy, not in generic terms like “improving patient experience,” but in ways tied to the organizational action plan and specific tactical priorities. That matters because it forces venture activity to support real operating goals rather than becoming a separate “innovation island.”

She offers a concrete example: Reimagine Care.

What makes this part of the conversation resonate is that it’s not delivered as a pitch. It’s delivered through lived experience. Rachel shares that her father was diagnosed with esophageal cancer and was treated at TGH. Navigating oncology symptoms and treatment side effects is complex. It can create a high burden on patients, families, and care teams. The number of messages to providers grows. Nurse lines have hours. Families worry about when they’ll get answers and what to do if they don’t.

In that context, Reimagine Care’s model, AI coupled with 24/7 clinical support, is framed as a practical solution: help patients manage symptoms, reduce avoidable emergency room visits, improve satisfaction, and reduce provider burnout. Rachel cites outcomes seen at other institutions: up to a 70% reduction in avoidable ED visits for oncology patients.

Whether or not every organization achieves that exact number, the point is larger: Tampa General isn’t investing for novelty. It’s investing in solutions that can produce measurable operational outcomes and relieve real clinical pressure.

This is also where her “beyond the walls” theme becomes clearer. She repeatedly highlights the fragmented nature of care, with patients often moving between settings, specialists, and touchpoints that don’t always connect. Innovation that matters, in her framing, is innovation that stitches that fabric together, so nothing falls through the cracks.

That “connective tissue” focus is not theoretical. It is the difference between a healthcare experience that feels like a series of disconnected transactions and one that feels coordinated and safe.


Scaling impact requires a thesis, governance, and the courage to commit

Rachel Feinman’s message is straightforward: healthcare doesn’t need more experimentation for experimentation’s sake. It needs a repeatable operating model that moves promising work into real impact.

At Tampa General, that begins with a refusal to linger in “pilot purgatory.” It’s not a rejection of starting small, it’s a rejection of staying small without decision. The approach is to start with a thesis, pick partners intentionally, measure results quickly, and scale fast when outcomes are proven.

She also offers a mature answer to a question that often paralyzes organizations. How do you move fast in a zero-risk environment? Her answer is to apply the right speed to the right domain. In other words, move fast in operational and administrative workflows where there is a massive opportunity, and “go slow to go fast” in clinical innovation by putting governance and guardrails in place early.

Finally, she points toward the real frontier: connecting fragmented care journeys and extending care beyond hospital walls, so patients experience a seamless system rather than disconnected silos.

The through-line is execution. Not ideas. Not pilots. Execution.


The Takeaway

Rachel Feinman’s view of healthcare innovation is refreshingly practical. In her world, the industry doesn’t need more pilots that drift without commitment; it needs an outcomes-driven model that starts with a clear thesis, measures value quickly, and scales what works with urgency. Her message is also nuanced: healthcare can and should move fast in logistics, access, and operational workflows, while using a “go slow to go fast” governance approach for clinical innovation where safety must be engineered upfront. In her framework, AI is a powerful accelerant, but only when paired with intentional partnerships, disciplined measurement, and a system-level focus on stitching together fragmented care journeys so patients experience continuity, not silos. The organizations that lead won’t be the ones running the most experiments. They’ll be the ones that can standardize, support, and spread proven solutions because their innovation strategy is built for scale impact, not just scale ideas.

Sitting at the intersection of strategy, deal-making, and real operational accountability inside a large academic health system, Rachel Feinman’s unique insights are especially valuable:

  • “Pilot purgatory” is avoidable when leadership mandates impact: start with a thesis, prove results, and scale quickly instead of drifting in endless tests.
  • Healthcare can “fail fast” in operational and administrative workflows, where logistics and coordination offer massive upside without compromising clinical safety.
  • For clinical innovation, the right approach is “go slow to go fast”: set governance and guardrails early so execution can accelerate later.
  • A health system venture arm creates the most value when investments are tied directly to the system’s strategic action plan and not generic innovation goals.
  • AI becomes meaningful when it compresses cycle time, turning insights into near real-time outputs that move stakeholders from discussion to action.
  • The next frontier is connecting fragmented care journeys and extending care beyond hospital walls, so patients experience seamless coordination rather than specialist silos.

Healthcare Needs Real Disruption, Not Incremental Change

Season 7

Episode 200 - Podcast with Stephen K. Klasko, MD, MBA, Executive in Residence, General Catalyst
Board Chair - DocGo, Teleflex

The Big Unlock
The Big Unlock
Moving Beyond Pilots to Scale Impact in Healthcare
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Season 7 | Episode 200

Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex -
Healthcare Needs Real Disruption, Not Incremental Change

The Big Unlock
The Big Unlock
Healthcare Needs Real Disruption, Not Incremental Change
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In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.

Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.

On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.

This guest appearance was facilitated through conversations initiated at Health Tech Summit by Cornell Tech.

About Our Guest

Dr. Stephen Klasko's professional history has been about not just disrupting healthcare but demolishing its sacred cows and rebuilding from scratch. As president and CEO of Thomas Jefferson University and Jefferson Health, he orchestrated a 567% revenue growth from $1.5 billion to $10 billion in nine years, while pulling off a merger of a 200-year-old health science university with a design school to reimagine "the human design experience in healthcare" starting at home. In a single year, he was named the #2 most influential person in healthcare and Fast Company's "Top 25 most creative people in business." He co-authored "Unhealthcare: A Manifesto for Health Assurance" with Hemant Taneja of General Catalyst—a battle cry against an industry he believes is fundamentally broken.

Now leading that change through his work at General Catalyst and DocGo, Klasko has spent his career proving that the biggest threat to healthcare innovation isn't technology, it's the traditionalists defending a dying system. Where others see academic medicine and Silicon Valley as opposing forces, he has built his legacy proving that they're the only combination powerful enough to save healthcare from itself.

As a DJ and doctor, he looks forward to 2026, when we, as the dreamers and designers of healthcare, can do an "ERAS tour"—Empathy, Radical collaboration, Access, and Swift care—and, as Sia sang, find the "courage to change."


Ritu: Hello everyone. Welcome to the Big Unlock Podcast. My name is Ritu and I’m your co-host today along with Rohit. I’m the managing partner at Damo Consulting and host of the Big Unlock Podcast. Really happy to have our listeners here today and to welcome Dr. Klasko to the podcast.

He’s one of the most provocative voices re-imagining the future of healthcare. In 2024, Becker’s Hospital Review named him as one of the great leaders in healthcare. He’s been recognized by Fast Company as one of the most creative people in business, by Modern Healthcare as the number two most influential person in healthcare, and by Ernst & Young as Entrepreneur of the Year.

Former CEO of Jefferson Health, he led its transformation into a national model for innovation, scaling it into a 14-plus hospital system. He’s also co-author of Unhealthy: A Manifesto for Health Assurance, where he challenges the industry to move beyond sick care toward true health assurance. Today, as an advisor and investor working with organizations like General Catalyst, he’s helping build the next generation of digitally enabled, patient-centered care models. Known for questioning long-held assumptions, Dr. Klasko continues to push healthcare leaders to rethink not just how care is delivered, but why the system even exists in its current form.

Really happy to have you with us, Dr. Klasko. With that I’ll pass it to Rohit for a brief intro.

Rohit: Thank you, Ritu. Hi everyone, I’m Rohit — CEO of Damo and co-host of the Big Unlock Podcast. It is a pleasure to have you, Steve, on the podcast. We had such a wonderful presentation from you at Cornell Tech recently. Looking forward to an engaging session. Thank you.

Stephen: Well, thanks. You guys did a better introduction than I could have done. When you’re 72, you have about five different careers — we could take the whole half hour. What I told someone at a Forbes conference: a young woman came up to me and said it seemed like everybody knows me. I said, look, I’m 72, I’ve been a healthcare leader for 40 years, I’m still vertical, and my first five Google pages are still positive. There are only about ten people who can say all four of those things.

The simple answer is I started my career as a DJ. I’m a high-risk obstetrician who delivered about 1,500 babies in private practice in Pennsylvania and Florida. Through a series of events, I got my MBA at Wharton and became one of the leaders in studying what makes doctors different and how we handle change. I became the dean of a couple of medical schools, including one where we selected a class based on self-awareness, empathy, communication skills, and cultural competence — not just memorizing the Krebs cycle.

Then I became CEO of two different academic medical centers: University of South Florida — which, interestingly, is not in south Florida but in northwest Florida, which tells you everything about the logic of Florida — and then Jefferson, which we grew from roughly a $1.5 billion single-hospital entity to an 18-hospital healthcare-at-any-address system with an insurance company.

One of the things I’m most proud of: we merged our 200-year-old health science university with the number-three design university and created the first MD/Master’s in Design — the design of the human experience in healthcare. Our mission became being a 200-year-old academic medical center thinking like a startup, really embodying the model of what you’d get if a Silicon Valley entrepreneur and a health system CEO had a baby. We tried to create that at Jefferson, and in some respects that’s what we’re doing at General Catalyst now. We’ve acquired a health system, Summa, and created health assurance partners like WellSpan and others. It’s taking both sides — the tech galaxy and the traditional healthcare ecosystem galaxy — recognizing that neither has all the answers, and trying to bring them together.

Ritu: Thank you for that wonderful introduction — three questions straight away from what you’ve said. Let’s start with the first one. You’ve talked about healthcare at any address: telehealth, distributed care, digital front doors. COVID really normalized that, but we still haven’t seen that system come fully to scale. What is the problem, and why do you think digitization and the digital front door haven’t happened so far?

Stephen: I’ll start with two quotes. One is from Peter Diamandis, who said the problem with disruption is that it disrupts your current line of business. And we haven’t been willing — insurers haven’t been willing, hospitals haven’t been willing — to disrupt their current lines of business. We all talk about it. We talk about value-based care like it’s some Greek mythology myth, because we haven’t figured out how to make it work by and large.

One of my mentors was Bill Kissick, who wrote a book 45 years ago called Medicine’s Dilemmas: Infinite Needs, Finite Resources. He was the first to talk about the Iron Triangle of access, quality, and cost. If you remember ninth-grade geometry, increase one angle and you have to decrease another. So if you increase access, you’re either going to increase cost or decrease quality — unless you’re willing to disrupt the system. And disruption is painful.

He said, in a nonpolitical way: if anyone ever tells you they’re going to increase access, increase quality, and decrease cost — and it’s not going to be painful — they’re not telling the truth. The day after the ACA passed, President Obama said it would increase access, increase quality, and decrease cost with no pain to anybody. Whether that was intentional or inadvertent, it clearly wasn’t true. Trump said his plan would be fantastic, terrific, unbelievable, and really huge — and it was none of the four.

In every other disruption of every other sector — Uber and taxis, Amazon and retail — the players that weren’t willing to be fundamentally disrupted went away. Think Sears and JCPenney. Circuit City thought they could go all-e-commerce and failed. Others said, “Holy moly, this is real,” figured out how to make their old model work alongside a new model — think Target and Walmart.

That’s largely what’s happening right now in healthcare. This is the first time in our history where just about everybody’s hurting. For the last ten or fifteen years, hospitals ruled the roost and told insurers what to do. Then payers said, “If you don’t do this, I’ll send all my patients elsewhere.” Just look at UnitedHealthcare — since the ACA it became the second-best-performing stock after Apple, and it’s a middleman. But now they’re hurting and the hospitals are hurting too.

The simple answer is: until we recognize that the system is broken, fragmented, expensive, and inequitable — and probably unsustainable, though we’ve been saying that for a long time — something has to give. It’s really like Hurricane Katrina, where everybody said the levees wouldn’t hold until they didn’t. We are literally at that point in healthcare.

Ritu: I totally agree with you. Even at Cornell Tech, something I wrote down from your talk: true change can’t be incremental and slow — it has to be jolting, and it has to hurt people.

Stephen: And people have to fail. Sears and JCPenney failed. Circuit City said “we’re going all-e” and failed. I did a lot of work with Target and Walmart when I took over Jefferson, and their whole philosophy was: we’re really good at what we do, we’re not going to abandon that, but we have to be just as good as Amazon at what they do. In one case they bought a new platform, in another they built one. That was an aha moment for me.

At Jefferson, we have one of the best pancreatic cancer surgeons in the world — Dr. Charles Yeo. If you have pancreatic cancer, you don’t care about our digital health strategy, our TV screens, or our food. You want to see Dr. Yeo, and people come from around the world for that. But for the other 97% of people in Philadelphia who don’t wake up thinking of themselves as patients, all we could say was: come to my office, my ER, my urgent care, my hospital. None of them wanted to do any of that. They wanted to be a person with diabetes or congestive heart failure or COPD who could thrive without having to think about it.

One of our first big successes at General Catalyst was Livongo — sold for $18.4 billion. All Livongo did, when you really think about it, was say: we’ll be your invisible friend if you have diabetes. They partnered with Jefferson and said, “Klasko’s great — but he’s great if you need his office, urgent care, ER, or hospital. That’s not what you need 97% of the time. We’ll be there for the other 97%.” That’s what tech, payers, and health systems have to learn to do together. The ones that can disrupt on access, quality, user experience, and cost will succeed.

Ritu: That leads into the new era — you’ve also talked about how the whole idea of the annual wellness visit is going to be outdated because of the constant stream of data coming in from wearables. People need AI companions, and they’re so used to getting everything on demand. The whole model of going into the doctor’s office, seeing the doctor, and then waiting for information is going to be very outdated very soon.

Stephen: The annual visit is a farce. Think about it — imagine if your entire financial life was managed by checking in once a year and ignoring everything in between. Oh, by the way, there was a war, or inflation ticked up four years ago. We’ll just check you annually. I had my Mayo Executive Wellness exam and they gave me all this guidance on exercise and weight loss. I’m a marathon runner. Two days later I tore my hamstrings. Everything they told me was immediately irrelevant.

If they had gotten the data from my Oura ring, they would have said, “Hey Steve, you were running 25 miles a week and you stopped on Tuesday — we’d like to talk to you.” Well, I didn’t just stop. I did a face plant because I tore my hamstrings and had them surgically reattached.

My new book is going to be called — as I mentioned at the Cornell talk — Swifties, Startups, and the Singularity, where I come back from 2035 as the Chief Digital Health Officer for President Taylor Swift, because the Swifties have become a political party. We could do worse. Our healthcare motto was “make healthcare Taylor-made, make it Swift” — neither of which was true in 2026. And one of the breakup songs was: we were never, ever, ever going back together with annual physicals. Even the term “physical” is asinine — it means I’m going to check everything from the neck down once a year.

One of the companies I’m involved with, NeurFlow, did a study showing that about 30% of people who have attempted or completed suicide had seen their primary care doctor within the last four or five months. They had a “physical” and the doctor didn’t connect what may have been a warning sign. NeurFlow actually connects those warning signs. So the whole concept of continuous health narratives and much more sophisticated wearables is critical.

I had a cardiac bypass two years ago. I left the hospital on day two — actually DJing for the nurses on day two. Typical cardiac rehab would have me sitting in a waiting room about five weeks later, getting wired up and walking on a treadmill. I’m a marathon runner — I wasn’t doing that. So I talked to my cardiologist and we connected my Oura ring and Apple Watch data. He had me start walking around week two, monitoring heart rate variability, and gradually increasing. I did it all from home at a much lower cost and was back to running within about eight weeks — whereas with the traditional approach I would just have been starting treadmill walking.

This healthcare-at-any-address model not only makes care more accessible but allows you to customize it. A lot of bypass patients are sedentary people who haven’t exercised — and that’s the one-size-fits-all model in American medicine. I had an autoimmune issue, a cholesterol of 107, and weighed 140 pounds. I didn’t need to prove I could walk on a treadmill.

Ritu: Absolutely. So Dr. Klasko, you’ve been championing radical collaboration between health systems and Silicon Valley for a while now. You mentioned Summa, but in practice, what is the biggest failure you’ve seen where collaboration looked good on paper but didn’t work in the real world due to culture, incentives, or ego?

Stephen: I think you answered your own question — culture and ego. Let me expand on that. First, here’s what we hear from health system CEOs: “We are tired of putting all the Lego pieces together for all the point solutions your 28-year-old founders create.”

I’m a board advisor to five very good women’s health AI and tech companies handling different parts of women’s health — fertility, menopause, the vaginal microbiome, pregnancy. Why don’t they get together and say, “Throughout a woman’s life, we can now do more of this at home”? It’s founder ego. I sometimes have to explain to these companies: you’re not going to create an IPO based on dense breasts, or vaginal microbiome, or one part of a woman’s life like fertility alone.

The second thing is that we haven’t been that successful in the past. As one CEO told me: “You spent 40 years telling us technology would make our life easier.” Start with what he called the epidemic of EHRs — they were supposed to make our lives easier and all they did was create more administrators. There’s real skepticism that AI isn’t just our new cool EHR.

And then the third thing is incentives. One of the things I’m proud of at Jefferson: I wrote an article called “I’m Never Getting Fleeced Again.” I was at University of South Florida and a CEO came to me in 2009 — a virtual health company, even back then. He said, “Steve, I want to take you out to dinner. We couldn’t have done it without you. USF was our first client.” I asked why the dinner. He said, “We just got valued at $800 million.” I said, “That better be one hell of a dinner, because we didn’t get anything out of that.” He said, “No, no — I’m also going to send you four fleeces.” So my article was “I’m Never Getting Fleeced Again.”

If I’m really involved in helping create billion-dollar companies, that has to change. At Jefferson, we literally put a General Catalyst person on our cabinet. We co-developed. With companies like Carrum Health, we gave them total access to all our doctors and systems, but we also had an opportunity to gain equity — not pay-to-play, just true partnership. When Carrum became a significant company, I didn’t feel like I’d helped create something and gotten nothing in return.

From Jefferson’s perspective, it was also a portfolio diversifier — which is what every health system needs. If you’re struggling to make a 2% margin on your hospital business and you can’t depend on investment markets continuing to grow 10 or 15% a year, while you’re getting less and less from insurers — meanwhile $30 billion is being spent on digital health and somebody’s making a lot of money, and they can’t make it without you — you don’t need to be a genius to ask: how do I participate in that in a legal and ethical way? That’s what I talk to hospital system CEOs and boards about.

Rohit: Steve, I’m thinking about the fact that hospitals are largely set up as not-for-profit — that’s in their DNA. You’ve been CEO of a not-for-profit system. Now you have General Catalyst, clearly driven by profit, with investors expecting a return, coming in through the Summa partnership. How do you bring those two worlds together?

Stephen: I’ve been on the board or in the CEO seat of three kinds of health systems: not-for-profit, for-profit, and religious faith-based institutions. Here’s what I’d say: by and large, the faith-based institutions were the most mission-driven and the least profitable. We started every board meeting with our mission. Beyond that, the distinction between not-for-profit and for-profit is much more variable than people think.

I’ve seen not-for-profit hospitals that talk about nothing other than donor dollars, US News & World Report rankings, and beating competitors in research. And I’ve talked to people like Jonathan Perlin, who was Chief Medical Officer for HCA and now runs JCAHO, who would push back on that. He’d say, “We probably did more to normalize obstetric care through our for-profit system.” Chip Kahn, head of the Federation of American Hospitals, would say: “The difference is we pay taxes.”

That said, there are absolutely for-profit systems I wouldn’t want to be part of — and there are not-for-profit systems I wouldn’t want to be part of either. When you get to General Catalyst, it’s a genuinely different situation. I know it’s easy for me to say, but when we wrote that book — Unhealthy: A Manifesto for Health Assurance — we called it a manifesto deliberately. And my partner, who I now have the honor of working for, made a decision that to truly actualize what we wrote, we have to prove it.

We did not go and acquire a sexy, profitable LA health system. We acquired Summa Health in Akron, Ohio — literally in the middle of the country, in the middle of how health systems are doing. They weren’t going bankrupt, they were in the upper-middle tier on quality, but not what everyone was talking about. A couple-billion-dollar, few-hospital system with a small insurance company. We have this principle called responsible innovation. We didn’t invest a few hundred million dollars there to come back with a quick profit. It’s a ten-year type of commitment.

And honestly, partly why I’m not the most directly involved — I’m 72, unless they’re building assisted living facilities. But it’s exciting and I think it’s being done for the right reasons.

What frustrates me is that I’ve been doing this for 40 years, and when you go to Health Evolution, Forbes Healthcare, or similar events, you’d think we have the most equitable, fair healthcare system in the world, because everybody’s talking about what they’re doing. We’ve been talking about the same transformations for decades. The quote I used at Cornell: Jason Kidd, when he came to the Dallas Mavericks who were 24 and 52, said “I’m going to turn this team around 360 degrees.” We do a lot of turning things around 360 degrees in healthcare.

I’m hoping that people who listen to the Big Unlock Podcast and who went to the Cornell Health Tech Summit are willing to say: I’m mad as hell and I’m not going to take it anymore. We’re not turning things around 360 degrees anymore. That’s my hope.

Ritu: Thank you. Thank you so much, Dr. Klasko. It’s been a pleasure.

Stephen: Thank you. Take care, everyone.

 

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

 

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Autonomous AI Turning Evidence into Action

Season 7

Episode 199 - Podcast with Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health -
Autonomous AI Turning Evidence into Action

The Big Unlock
The Big Unlock
Autonomous AI Turning Evidence into Action
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In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.

Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.

Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.

This guest appearance was facilitated through conversations initiated at ViVE.

About Our Guest

Dr. Eric Stecker is the co-founder and Chief Medical Officer at Insight Health, a cardiologist and professor of medicine at Oregon Health and Science University. He chaired the American College of Cardiology’s Science and Quality Committee, which is responsible for national cardiology practice guidelines and other clinical policy documents. He maintains a practice that focuses on advanced ablation and device implantation. He received a B.S. and M.D. in the Medical Scholars Program from the University of Wisconsin Madison. He received an M.P.H. with a focus on health management and policy from the University of Michigan.


Ritu: Hi everyone. Welcome to our next episode of the Big Unlock Podcast, season seven. We are really excited to have Dr. Stecker with us here today. Dr. Stecker is the Chief Medical Officer and co-founder of Insight Health, where he’s focused on applying artificial intelligence to improve real-world clinical outcomes.

He’s also a practicing cardiologist and professor of medicine at Oregon Health and Science University. His work sits at the intersection of cardiology, data science, and population health, with a particular emphasis on translating predictive insights into actionable interventions. Dr. Stecker has been a leading voice in how AI can move beyond detection to truly impact prevention and care delivery.

Today he’s joining us on the Big Unlock Podcast to explore how intelligent systems are reshaping the future of cardiovascular care. With that, a very warm welcome to all our listeners. Dr. Stecker, thank you so much for joining us today.

Eric: Hi. Thank you. It’s great to be on your podcast. It’s really an honor, and you’ve had some great guests and explored some great topics in the past.

Ritu: Thank you so much, Dr. Stecker. We are really excited to have this conversation because we just came back from HIMSS and AI was everywhere. One of the more interesting things — we went to the Cornell Health Tech Summit and they really talked about wearables and this constant stream of data that’s coming in, and how that’s going to make the annual physical obsolete.

We would love to hear your thoughts on the future of continuous cardiac care with wearables and remote monitoring with AI. Do you envision a future where cardiology becomes a continuously managed condition? And if so, how?

Eric: I think there are some very exciting possibilities, and I’m glad you brought up the idea of continuous health management and continuous monitoring.

That’s an area that’s created great excitement for many people, and I do think it is in our future. It’s important, though, to distinguish that which is an evolving evidence basis. In clinical medicine, putting my academic cardiologist hat on for a moment — there are a variety of interventions and monitoring approaches we can employ, and what we emphasize depends on what is most beneficial for patients. Continuous wearables and continuous physiologic data monitoring has some evidence for benefit, and I think that will evolve significantly over time.

It’s an area where AI can intersect very well and very effectively, once autonomous AI agents are tested and FDA approved. It’s important to recognize, though, that there is a whole set of health interventions we know are very high-impact and beneficial — we just need to work on implementing them. We know what to do; we just need to do it, and AI can really improve care for those things right now.

We don’t need new technology or large clinical trials to show benefit. We have decades of very high-quality clinical evidence. Take statin medications — cholesterol medications for patients at high risk of cardiovascular events or with known heart disease. We have hundreds of thousands of patients studied in clinical trials showing significant benefit, yet identifying those patients, starting them on medication, and supporting them to ensure they take it as prescribed — these are the challenges we face right now. That gap results in hundreds of thousands or even millions of additional heart attacks and cardiovascular deaths. This is something AI can dramatically improve today, without the need for any further study.

Ritu: That’s a great answer — lots to unpack there. You talked about autonomous AI agents, and within Insight Health you’ve had particular success building a suite of these agents. We’d love to hear more about that. I also read a news update that you were recognized by OpenAI for crossing one billion tokens. What’s happening there?

Eric: Yes, thank you. I wish Sara, our CTO and co-founder, were on — he posted something about when we got the plaque for a billion tokens. We use multiple models, by the way, but for OpenAI specifically, by the time the plaque arrived in the mail, we’d already crossed ten times that threshold.

To back up a moment — the idea for our company: we have four excellent co-founders, which is a little unique. Two of us are mid-career physicians who have been practicing clinical medicine for some time and continue to do so. We’ve had to scale back significantly to build this company, but we love clinical medicine and our goal was to remove the roadblocks and allow us to have much more impact for patients in a much less painful way. There are so many speed bumps and potholes in the clinical care delivery system.

The idea came about when my co-founder Dr. Gore — our other Chief Medical Officer — and I went for weekly runs every Saturday morning, rain or shine in the Pacific Northwest. I remember it was early December 2022, dark, rainy, cold, probably 45 degrees. ChatGPT had just burst into public consciousness. Gore said, “This will transform medicine.” We were not in the tech world, not CS folks, so it took us by surprise too. We thought, this will transform medicine — we have to be involved and help guide where it goes for doctors in general and for us specifically. That was the genesis.

We were then connected — his brother is a Silicon Valley entrepreneur with a lot of contacts — and he connected us with Jay Malson and ultimately with Saron Siva. We created the company, and within six or eight months, we had, to our knowledge, the first autonomous interaction with a patient in real clinical practice. This is a specialist practice, which has been our initial focus.

There’s a lot of great technology being developed. Google, for instance, was doing some really great work at that time. But because it was being driven from the tech end rather than the clinical medicine end, they were using patient actors to do scenarios and working on the clinical intelligence layer from that angle. We understood that interacting with patients and intelligently offloading what AI can handle — allowing patients more time to discuss their condition, talk about their symptoms, and ask certain questions within guardrails — we knew that technology could do that, and we knew that was a big part of the benefit for clinicians and patients.

We were confident enough, with our clinical experience and the technological experience of our other two co-founders, that we could make this work. In the first example, we actually had a nurse sitting with the patient in the clinic. About the first week, a nurse was right next to the patient. Then we recognized, “Hey, this is working — let’s release it and let patients do it in their own homes.” That was the genesis.

Since then, we’ve built out a suite of autonomous AI agents that can interact with patients, review referrals, review prior authorizations, summarize the clinical encounter — you’re very familiar with AI scribes — and reach out to patients after the visit. All of these are orchestrated via sophisticated technology, allowing for a much more AI-intensive experience that still feels very comfortable for the patient and for clinicians.

Ritu: That’s really interesting, because we keep hearing that AI actually just augments humans. What has your experience been in reality? Are we over-romanticizing “human in the loop,” and at what point does AI need to take more autonomous decision-making? You mentioned that you eventually removed the nurse because AI was fully capable of handling it on its own. Would love to hear more about your thoughts on that.

Eric: I think you raise a couple of excellent points. I would divide autonomous action from autonomous decision-making — I think those are two separate things. They’re often conflated, and understandably so. The reason I separate them is that once you move into the world of AI making clinical decisions and issuing orders without a human in the loop, it requires a lot of technological work — both on the fundamental technology operations and on the AI safety assurance overlay layer.

It also requires a ton of clinical validation, testing, and oversight. That’s very important. We do not have enough clinicians — not enough specialists or primary care providers — so it’s very important to move in that direction. But it’s very difficult. The other challenge is trust: patient trust and healthcare worker trust among those working alongside autonomous decision-making AI within the healthcare ecosystem.

Most important, of course, are patients — they’re the center, and the reason we deliver healthcare. So autonomous decision-making is important and will come and needs to be developed, but I think we should avoid an excessive focus on it, because there is so much low-hanging fruit to pick right now to improve care through autonomous action.

There’s also appropriate debate about whether AI is really saving clinicians — or are they just having to look through more data generated by the AI scribe? Are they having to double-check for hallucinations? The answer is: absolutely, well-designed and well-implemented AI can act autonomously in a way that really improves both the clinician and patient experience. It has to be done well, but that’s something we can and are doing right now.

There’s so much benefit — and by benefit I don’t just mean healthcare efficiency and its positive financial ramifications for health systems and payers. I also mean patient outcomes: reducing death and disability from disease. We know what we need to do. We need to diagnose high blood pressure, prescribe appropriate medications, and support patients. Wouldn’t it be wonderful if every time a patient was started on a new medication, a nurse — whether an AI nurse or a real nurse — contacted them and asked: “Did you fill that prescription? How’s it going? Are you having any side effects? Do you have any questions? And when would you like me to check in again?”

If a patient says, “Check in with me in a month” — you check back in a month. Are they still taking the medication? Is it okay? Just that action can dramatically reduce mortality among middle-aged and elderly people in the United States, simply by diagnosing high blood pressure, suggesting the correct medication for the clinician to start, and then checking in with the patient. This is not a “sending rocket ships to Mars” kind of thing. We can do this right now — and in fact, we do.

Ritu: That’s a very important distinction you’ve made between autonomous action and autonomous decision-making — something really worth thinking about. Thank you for clarifying that. But that leads directly into the next question: you made a correct point about ambient AI and other tools generating more data and cognitive load for clinicians. AI can generate a flood of alerts, risk scores, and predictions — more and more information. What are your thoughts on the signal-to-noise problem? How do you ensure AI is surfacing the right interventions without overwhelming clinicians or patients? At what point do you decide how much is enough?

Eric: That’s absolutely right. Using that example — if you’re checking in with patients weekly on an oncology issue and you generate a three-quarters-of-a-page summary every time and push it into the EHR, somebody then has to look at it and decide what to do.

This is exactly why having clinicians involved in technology development and implementation is critical. Dr. Gore and I are mid-career — we’ve been attending physicians for 15 to 17 years. We have a lot of experience in clinical medicine, and we still love it. We’re not looking for an exit; we’re making our ecosystem better.

Involving clinicians in a meaningful way — not just as Chief Medical Officers with a couple of consulting meetings here and there, but actually integrating them into product development and implementation — that will be essential. Because exactly what you raised will be highlighted immediately. “Wait, you’re checking in with this patient twice a week — how do we manage that information? Only escalate medical flags. We need a protocol to distinguish routine symptom responses from things that require documentation. Maybe it’s a floating dashboard.” Involving experienced clinicians is the key. If you leave this only to people who have an MD but never practiced, or only to technology developers, the issues you highlight will be a major problem.

I don’t want to whitewash this — the technology advances so fast that sometimes we need to catch up. Having AI scribe documentation that’s two pages long may suit some clinicians, but it creates a huge cognitive load for many others. You really need abbreviated summaries that highlight key things.

You also raised alert fatigue, which is extremely well-documented and a serious problem. I’m old enough to remember paper charts in medical school. When EHRs first came out, everyone was splashing alerts everywhere, and people just clicked “Okay” to get through them. That issue is better understood now, but we may be entering a new era with AI where we need to relearn that lesson. I hope not — and the more experienced clinicians are involved, the quicker we’ll learn it.

Ritu: It’s really interesting to hear that you’re mid-career and still love medicine. That reminded me — we usually start the podcast with an origin story about how you got into healthcare, and we didn’t do that this time. We’d love to hear how you got into this, how you chose cardiology, and how you got interested in the intersection of technology and healthcare. Doctors really bring a unique perspective because you’re there every day and you know what needs to work.

Eric: My father is an engineer and my mother is a social worker, and I am an amalgamation of those two ways of thinking — which is a great fit for medicine: thoroughly analytic, but also with the interactive and social insight that social work requires.

The reason I got into cardiology is that, honestly, memorization is not a strength of mine. To get into medical school you generally need to be an excellent memorizer, and I’m about average for a smart person — which, compared to the average medical student, makes me a bad memorizer. I was somewhat dismayed in the first couple years of medical school, memorizing lists and being graded on how many items out of ten or twelve you could retain. I did fine, but it was painful.

What I loved was physiology — how systems work together. I would understand it quickly, remember it well, and integrate it into practice. In my third and fourth years, I recognized that cardiology is rich with physiology, and that you can have a major impact on patients’ health and longevity. The interesting procedures, depending on the specialty, were also a draw. For all those reasons I gravitated to cardiology and ultimately to electrophysiology.

As for technology — my father worked at an engineering company, and when Oracle first became available to consumers, we got it: floppy disks and a shelf of manuals two feet long. I learned Oracle, worked at my dad’s company, and created SQL databases. That gave me a taste for technology, a sense of it. I never pursued it further — no programming, no CS degree — but it kept me interested and involved. And ultimately, that’s how Dr. Gore and I thought of the idea and then contacted our other two co-founders to start the company.

Ritu: Very interesting. Thank you for sharing that, Dr. Stecker. Do you think the role of the cardiologist is going to get redefined in an AI world as AI takes on more diagnostic and predictive tasks? How do you think the field needs to evolve to keep up with this wave of technology that seems to be threatening to overwhelm many specialties and healthcare in general?

Eric: I sure hope it will absolutely happen. My hope is that clinicians and patients do not need to evolve too much — that the main issue is establishing comfort and warranted trust with the implementation of technology, but that the technology can fit around the current experience and improve it dramatically, unlike EHRs of 15 years ago — or frankly right now.

An example of that is our autonomous AI agents that reach out to patients before visits to gather their basic medical history, understand a patient’s pain syndrome in detail, or for a cardiology patient, understand what procedures they’ve had done and where. All of this can happen at 2:00 AM if the patient is a shift worker — in their own home, on their own time. It doesn’t have to happen in the waiting room. All the questions the doctor or nurse might ask at the beginning of the visit can be handled in the comfort of the patient’s own home. That’s an example of how technology can work more effectively and can work around the needs of the patient.

Ritu: Meeting the patient where they are rather than having the patient come to you. When you talk about these autonomous agents, are you specifically talking about voice agents or how are they operating?

Eric: There are voice agents — you call up and talk with a very natural-sounding AI agent by voice only. There are also text-based interactions. Our company has technology we call “visual voice,” where it’s like texting on your phone as you’re speaking — and as the AI communicates with you, it can also pull in videos to that stream. For instance, instructional videos. An example: as an electrophysiologist dealing with arrhythmia, I frequently send out rhythm monitors. A company can send one straight to a patient’s home and they can put it on themselves. It has instructions, but if they don’t know how, our visual voice can show them a video right there — “Put it here, do this, click that.” You don’t have to look it up on the internet or call an 800 number for help.

There are many different interactive modalities. Again, this fits with the theme of making this as accessible as possible to patients, because that’s going to promote their engagement with their health and doing what we know will promote longevity.

Ritu: With all the implementations you’ve seen so far at Insight Health, have you seen particular success in any specific category, or do you think agents are generally successful across the board?

Eric: We have seen a lot of success. It very much depends on the context — whether it’s a mid-size clinic, an insurer, a smaller or large health system. The needs will be very different for each. That’s the strength of the deep tech stack we’ve developed; we can fit any kind of need.

One example, in keeping with public health — I have a master’s in public health as well — there is a well-established set of preventive activities: colorectal cancer screening through colonoscopies or stool-based or blood-based testing, breast cancer screening, cholesterol checks, blood sugar checks. These are very well established as beneficial, but it’s very challenging for payers and insurers to transmit that down into health systems, clinics, and to patients — even when they’re highly motivated and have bonuses aligned to good care through Medicare plans.

Payers have limited ways of intervening on those gaps. Say 50% of patients aren’t getting colorectal cancer screening, and death from colon cancer is much higher in their panel than it should be. Our technology can screen, reach out to the patient, assess their interest in colorectal cancer screening, educate them about it, assess their preference — colonoscopy, stool-based home test, or blood-based test — and then actually arrange it. It can schedule the colonoscopy, arrange prep, and screen whether they need to see a gastroenterologist first or can go straight to colonoscopy.

For me, the most impactful work is what touches public health and population health. But I recognize that every clinic and every clinician has different pain points, and we can insert ourselves into any of them.

Ritu: Time’s flown by and we’re almost at the end of the podcast — it’s been a great discussion. Thank you so much, Dr. Stecker. Any last thoughts or closing advice you’d like to share with our listeners before we wrap?

Eric: I know you’ve got a sophisticated audience, and I think it’s important for them to realize that as we progress along the spectrum from autonomous action to autonomous decision-making, it will be critically important to engage the workers within healthcare organizations to ensure it’s implemented well and that trust is established. And, of course, ultimately the patients.

The further upstream we are from patient interaction, the less critical that trust-building is. If it’s point solutions working on the back end of the healthcare ecosystem, that’s relatively straightforward. If it’s patient-facing, it’s really important to work with experienced people who can do it well. And as we progress toward the world of autonomous decision-making, wearables, and constant care delivery, we’ll really need to work through what that means as a society and build acceptance before it can gain traction.

Ritu: It might be happening sooner than we realize — the COVID era of AI. Thank you so much, Dr. Stecker. It’s been a pleasure having you on our podcast.

Eric: Thank you. It’s been a great time.

————Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Turning Healthcare AI Hype into Real-World Execution

Turning Healthcare AI Hype into Real-World Execution

Insights by Aditya Bansod, CTO and Co-Founder of Luma Health

“Healthcare doesn’t have an ‘AI imagination’ problem. It has an execution problem…” said Aditya Bansod, CTO and co-founder of Luma Health, on a recent episode of The Big Unlock podcast. It was a point that he made repeatedly as he discussed why healthcare AI often underdelivers, and what leaders must do to turn promise into performance with our host, Ritu M. Uberoy.

With a lifelong passion for building software, Aditya leads Luma Health’s technical vision and strategic direction for building a platform that empowers healthcare providers to better serve their patients and improve healthcare outcomes. His central claim is simple: many AI tools underperform in healthcare not because the models are weak, but because the workflows are messy, the handoffs are human, and the infrastructure is stitched together with a mix of modern platforms, legacy systems, and unstructured communication.

Or as the episode hints early on: healthcare still runs on “cutting-edge tech and clipboards.”

Aditya’s perspective is grounded in a very specific mission. Luma doesn’t “do medicine” or “do science,” as he puts it. Its job is to make it easier for patients to see their doctor. It sounds simple. It’s not. And that “unsexy last mile” is exactly where AI hype either becomes real—or collapses under the weight of reality.

As he told Ritu, “We don’t do medicine, we don’t do science. Our simple job is to make it easy for the patient to see their doctor… and that is just like such a hard part of the healthcare experience.”

Healthcare AI Often Fails at the “Handoff Problem”

One of Aditya’s most practical insights is that healthcare isn’t a single workflow. It’s a chain of workflows, where patient care passes from Medical Assistant to RN, RN to physician, physician to billing, etc.

He describes it as the “connective tissue” of healthcare operations. And he argues that humans, for all their imperfections, are still better than software at passing context along.

“The amount of connectivity and the amount of tissue inside the health system that exists to do that. It’s honestly, kind of unbelievable. And it works because humans are exceptionally good at passing context along – in fact, despite what most people may think, they’re better than computers at it.”

That becomes a direct critique of many AI “point solutions,” especially those that operate with limited connectivity to the broader system. You can build an AI voice agent that schedules an appointment. But what happens to the nuance a human would capture in the call? Does it land in the chart? Does it trigger transportation assistance? Does it cue interpreter services? Does it flag a mobility issue that affects how the patient should arrive? Aditya’s argument is that these details are often the difference between “automation” and “execution.” “All the little nuances that a human would pick up… do those make it into the chart?”

He gives a simple example: a patient might mention pain, difficulty walking, or barriers to getting into the car. In a human handoff, someone says, “Get them a wheelchair.” In a disconnected automation, that context can evaporate.

In other words, AI isn’t failing because it can’t talk. It’s failing because it can’t reliably connect that talk to the operational reality of healthcare.


Why “More AI Tools” Can Make Execution Worse

A second theme in the episode is what Aditya calls a “Cambrian explosion” of AI solutions, which he defines as “massive funding and rapid product creation aimed at a limited set of problems.”

The result is predictable. CIOs and CTOs are now flooded with tools that overlap. In real health systems, that means multiple vendors trying to solve adjacent workflow steps, each with its own UI, logic, and integration story.

Aditya describes the situation bluntly: health systems often end up buying overlapping “Venn diagrams.”

“You’ve effectively purchased eight overlapping Venn diagrams.”

This isn’t just annoying. It’s operationally dangerous. It can create fragmented workflows where each tool works “in isolation,” but the overall journey breaks.

He uses colonoscopy scheduling and prep as a vivid example. Even when a patient shows up, if prep wasn’t done correctly, it’s functionally a no-show. That’s a workflow with multiple inputs: patient outreach, prep instructions, prior authorizations in some cases, outside medical records, follow-up confirmations, and staff readiness.

The lesson is that patient access is not a single “AI function.” It’s an orchestration problem.

Aditya argues that most health systems do not want to become software companies. They don’t want to build massive development competencies. They want to deliver care. But they will need something in between which he explained is “an integration and workflow-orchestration competency.”

“Most CIOs… don’t want to build a software competency… but they ultimately have to build an integration competency.”

He makes a useful comparison to the post-2020 rush. “Many systems rapidly bought telehealth, texting, and remote monitoring platforms during COVID, then spent the following years rationalizing app sprawl.” He predicts healthcare AI will follow the same path, except this time the emphasis won’t be only rationalization. It will be workflow-level orchestration.

The implication for leaders is uncomfortable but clear: the “AI era” will create more integration work before it creates less.


Autonomy is Coming Faster Than Expected, and it’s Already “Exception-Driven.”

In the episode, Aditya also tackles one of the biggest tensions in healthcare AI right now: “human in the loop” versus agentic autonomy. The CTO offers a nuanced and very practical way to reconcile it. He jokingly compares health systems to Maslow’s hierarchy of needs. Each system has its own “AI hierarchy.” Some are just trying to help physicians with basic burden reduction. Others are experimenting with agents handling more autonomous interactions.

“Every health system has their AI hierarchy… everyone’s kind of converging.”

What surprised him was how quickly organizations are moving up that hierarchy.

He shares a recent conversation where a health system was already letting AI agents perform medication reconciliation with patients. His reaction is basically: “Already?” That moment captures the acceleration happening in 2026: many organizations are moving toward autonomy faster than the cautious voices predicted.

One reason is consumer normalization. Patients are already using AI tools in their own lives, sometimes even connecting personal health records to ask questions. The gap between consumer behavior and health system adoption is shrinking.

“Consumers are demanding it… patients are consumers.”

The second reason is more operational: exception-based work is already how healthcare runs in many places, especially in the revenue cycle. That pattern is now being applied to AI.

Aditya describes Luma’s AI fax and order-processing workflows. He expected customers would want humans verifying everything. Instead, some asked for exception-only review: let the system handle what it’s confident about, and route low-confidence cases to people.

“Just give us the exceptions… the stuff where we have like 95% confidence, let it ride.”

That’s an execution mindset, not a hype mindset. It treats AI as a workflow engine with adjustable controls not some kind of a “magic brain.”

Aditya explains how Luma approaches guardrails in two layers:

First, compliance and standards. He points to emerging frameworks and programs that are beginning to create “best practice” scaffolding for AI governance and auditability.

Second, product design. Different health systems want different thresholds. Some want higher automation earlier. Others want more human review. The software needs to let clients “turn the knob” and increase autonomy over time as confidence grows.

He even offers a clear Luma opinion: full automation above 90% confidence, based on a “judge” pattern where one model produces output and another evaluates it.

“If the AI thinks it’s 90% right… fully automate anything above 90%.”

It’s a practical approach to what he says is a practical reality; healthcare doesn’t require perfection to move forward, but it does require controllable risk.


The Messy Middle of Healthcare AI: Platform Promises vs Real Connectivity

If there’s one phrase that captures Aditya’s overall stance, it’s “messy middle.”

He argues that the true “platform moment” in healthcare AI doesn’t exist yet. Not fully. Not in a way that makes workflows seamlessly orchestrated across systems.

He points to signs of progress such as vendors talking about workflow frameworks, others exposing the capabilities that agents can do, but he emphasizes that connectivity is still the bottleneck. A standalone capability doesn’t solve orchestration.

“I don’t think that platform exists today.”

His timeline is realistic: likely two to three years before the market rationalizes from “a vendor for every job” to “a few vendors covering most jobs,” creating a workable ecosystem.

He describes it as moving from 70 vendors solving 70 tasks to a small number of vendors solving most of the jobs-to-be-done between “I need care” and “care delivered.”

That’s a clear execution thesis: healthcare AI won’t win by stacking more tools. It will win by consolidating, integrating, and orchestrating.


The Takeaway

Aditya Bansod’s message is one we do not hear often enough: healthcare doesn’t need more AI hype or more “shiny” point solutions. It needs workflow-level execution that actually gets patients from intent to appointment to completed care. In his view, AI underperforms when it can’t carry context across human handoffs, when it adds another disconnected tool into an already fragmented ecosystem, and when health systems are forced to stitch together overlapping solutions without a true orchestration layer. The path forward is practical: build integration competency, design AI to work as an exception-driven engine rather than a brittle automation and give health systems adjustable guardrails so autonomy expands as confidence grows. The winners won’t be the organizations with the most pilots. They’ll be the ones that can connect the dots because their technology choices are aligned to real workflows, real handoffs, and real execution.

Sitting at the intersection of Silicon Valley product discipline and the unglamorous “last mile” of healthcare access, Aditya Bansod’s unique insights are especially valuable:

  • Healthcare AI fails most often at the handoff—because context is passed through humans, not systems, and disconnected tools lose nuance.
  • AI voice and scheduling agents won’t scale as point solutions unless they can push meaningful context into downstream workflows (charting, services, escalation).
  • The market is experiencing a “Cambrian explosion” of overlapping tools, forcing CIOs into integration and rationalization—whether they want it or not.
  • The near-term goal isn’t one perfect platform; it’s workflow orchestration across multiple tools until consolidation catches up.
  • Autonomy is arriving faster than expected, and exception-based work queues are the practical bridge between “human in the loop” and agentic workflows.
  • Responsible scaling requires adjustable confidence thresholds and clear guardrails—so automation increases gradually as systems build trust in performance.

Augmenting Care and Strengthening Trust with Healthcare AI

Augmenting Care and Strengthening Trust with Healthcare AI

Insights by Dr. Andrea Willis, SVP & Chief Medical Officer, BlueCross BlueShield of Tennessee

Healthcare AI is often discussed through a provider lens, hospitals, clinician workflows, documentation, and bedside impact. A recent episode of the Big Unlock Podcast showcased a different perspective, when Dr. Andrea Willis, Senior Vice President and Chief Medical Officer at BlueCross BlueShield of Tennessee, brought a “payer-and-population-health” view of what “responsible AI adoption” actually looks like in the real world. As she explained to host Ritu M. Uberoy, “AI doesn’t live in a demo. It lives inside care management, utilization management, pharmacy, quality, equity, member experience, privacy, and governance.”

Since those areas sit at the center of trust in healthcare, Dr. Willis’s definition of “responsible AI” is grounded in practicality. For her AI must make the system feel more supportive, more understandable, and more transparent, without creating new fear, confusion, or skepticism.

The conversation also opens with an origin story that subtly signals how she approaches healthcare itself. Growing up in Athens, Alabama, a young Andrea heard a mother cat in distress in her grandparents’ shed. She grabbed dishwashing gloves and scissors and went to help. With a little massage, the kitten was delivered successfully.

“That was my first delivery,” she says, and she knew from that moment she would become a doctor.

It’s a memorable story, but it also works as a metaphor for the episode: responsible AI should help reduce pain, reduce fear, and make the system more responsive, without stripping away the human support people need most.

Where Payers Apply AI First: Care Management and Utilization Management

When asked where AI sits today and how organizations move beyond pilots, Dr. Willis points to two areas where payers can drive real, scalable change: care management and utilization management.

In care management, her focus is not “automation for automation’s sake.” It’s the quality of human interaction. She describes an AI-enabled care management experience that compiles what the organization knows about a member so the care manager can stay “fully present” during the conversation. AI can summarize history, capture interaction context, and prompt next steps, reducing the invisible work that usually surrounds member outreach.

In other words, the AI isn’t there to replace the care manager. It’s there to remove the background burden so the care manager can listen, respond, and connect.

That matters because Dr. Willis repeatedly emphasizes a human reality that is members often are scared. They want to feel heard. They want to feel like the system understands what’s happening and what happens next. When a care manager has to spend the call searching, toggling screens, and trying to piece together context, the member can feel the distance.

Responsible AI adoption, in her framing, is partly about creating space for humanity. It helps care teams spend more energy on the person and less energy on the process.

In utilization management, she is unusually direct about the purpose of AI. She acknowledges that across the industry, AI is being explored in utilization management workflows. But she draws a clear line: AI is not meant to deny care. The goal is to bring relevant information forward, so approvals happen faster and decisions are clearer.

“We already have some pilots in place for utilization management and are looking at where we need to make tweaks before we scale it out broader, but that is something we’re looking at on the utilization management side of the house. Where we can bring all the information that we have in the system to bear so that we can get to approvals faster.”

Dr. Willis’s position is that responsible AI in utilization management must balance speed and transparency, enabling faster, more accurate decisions by surfacing the right context, while keeping accountability and evidence-based criteria at the center.

She also notes that beyond these outward-facing use cases, her organization is collecting employee ideas broadly to identify other innovation opportunities. That’s an important point for scale: responsible adoption is not only a single “AI project.” It’s an evolving capability built across teams, with shared learning and shared accountability.


Designing for Relevance: Why “All Data” is Not the Same as “Useful Data”

One of the most practical segments of the episode comes when Dr. Willis talks about learning from limitations early before an AI-enabled workflow becomes widely used.

She describes the importance of testing in controlled environments prior to broader rollout, and then she names a scaling challenge that shows up quickly in healthcare operations: relevance.

AI can compile a member’s information, but compiling “everything we have” isn’t the same as delivering what’s helpful in the moment. A diagnosis from years ago or medications that were once relevant may not reflect what the person is dealing with now. Without smart parameters, AI output can become cluttered, distracting, and potentially misleading.

Her point is simple, responsible AI needs guardrails that focus on what still matters clinically and operationally.

“This is a scalability insight hiding in plain sight. Many AI pilots fail not because the model can’t do the task, but because the output is too broad, too noisy, or too unfiltered to be usable at speed. In payer environments where teams manage large populations with long histories, relevance becomes everything,” she explained to Ritu.

Dr. Willis extends this mindset into digital care management more broadly. She notes that digital self-service can be very appealing. She says members do want convenience, but healthcare is complicated, and self-service cannot be the only answer. That’s why she emphasizes guided self-service, a model where members can complete routine tasks digitally, but the system can detect when someone needs more support than self-service can provide.

Guided self-service is a responsible adoption strategy because it avoids a common pitfall, pushing people into digital tools that feel like dead ends. It respects the fact that some needs are simple and some are not and the experience should be designed to escalate appropriately when the situation requires more help.


Measuring Success the Payer Way: Outcomes, Closed gaps, and Real Engagement

Dr. Willis grounds the conversation in successful metrics that actually translate into operational value. In care management, success isn’t “AI adoption” as a vanity metric. It’s whether member goals are met.

That could mean resolving an acute need, supporting a chronic care plan, closing a gap in care, or helping someone navigate a safe transition home after hospitalization. It’s practical and member centered. AI should answer: did the person get what they needed, and did the system help them move forward?

She also talks about engagement in ways that feel directly applicable. When members are informed that care management support is available, engagement rises and the downstream outcome is more gaps closed and more needs met.

She adds something many operational leaders recognize as a “quiet success metric”: when teams see what’s possible, they start generating better ideas. Innovation becomes a flywheel. Staff bring forward new use cases, new workflow improvements, and new ways to reduce friction because they can see the system improving.

In payer environments, that matters. Scaling isn’t just a technical process. It’s an organizational learning process. The more people understand the tools, the more they can apply them responsibly. This leads naturally into the broader adoption strategy she describes, which is making AI literacy a shared responsibility rather than a niche expertise.


Transparency and Governance are the Real “Scale Engines” for Responsible AI

Dr. Andrea Willis makes a point that she feels often gets lost in the excitement around new models, responsible AI at scale is less about flashy capability and more about the operational conditions that make people trust the system.

From a payer perspective, trust is built when decisions can be explained clearly, in plain language, and when the process feels consistent and evidence based. It’s also built when information can flow to and from all involved parties so fewer decisions are made in an “information vacuum,” and fewer stakeholders feel like someone else is acting without the full story.

What stands out in this conversation is her insistence that AI should reduce friction, not create new confusion. In care management, that means AI should help care teams stay present with members by handling background work like summarization and next-step prompting. In utilization management, it means AI should accelerate clarity and approvals by surfacing the right context faster, never functioning as a tool designed to deny, but as a tool designed to move the right decisions forward efficiently and transparently.

And finally, she offers a useful metaphor, mobile banking. People didn’t trust it immediately. They adopted it gradually as it became more helpful, more friendly, and more aligned with their needs. Healthcare isn’t banking, but the adoption lesson is real; people use what they trust, and they trust what they can understand.


The Takeaway

Dr. Andrea Willis’s message is refreshingly practical – responsible AI adoption in healthcare is not about chasing the newest model or launching endless pilots, it’s about building trust through real-world usefulness, relevance, and transparency. From a payer perspective, AI earns the right to scale when it helps care managers stay fully present with members, filters information so teams focus on what matters now, and accelerates approvals by bringing evidence-based context forward rather than creating new friction. In her framing, responsible adoption also depends on the infrastructure most people overlook, clearer explanations in plain language, stronger interoperability so decisions aren’t made with missing information, and cross-functional governance that protects privacy while enabling progress. The organizations that lead won’t be the ones experimenting the most. They’ll be the ones that can standardize, explain, and scale what works because their workflows, transparency practices, and oversight are built for trust at scale.

Sitting at the intersection of clinical accountability and large-scale operational impact, Dr. Willis’s key insights are especially valuable:

  • Responsible AI must reduce cognitive burden, not increase it.
  • Responsible AI is often the most human use of AI: it helps care managers stay present while the system handles summarization, organization, and next-step prompting.
  • Scaling fails when relevance fails. AI must filter out old or non-actionable history so teams focus on what matters now.
  • Guided self-service is the practical middle path: empower members digitally, but escalate to human support when needs are complex.
  • In utilization management, AI should be used to speed clarity and approvals, not as a mechanism to deny care.
  • Transparency in plain language is a trust engine—especially for prior authorization outcomes and denials.
  • Responsible scaling requires interoperability, governance, and AI literacy so adoption moves from pilots to repeatable, trusted impact.

Moving Beyond Pilots to Scale Impact in Healthcare

Season 7

Episode 198 - Podcast with Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures,
Tampa General Hospital - Moving Beyond Pilots to Scale Impact in Healthcare

The Big Unlock
The Big Unlock
Moving Beyond Pilots to Scale Impact in Healthcare
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In this episode, Rachel Feinman, SVP of Innovation and Managing Director, TGH Ventures at Tampa General Hospital, shares how the organization is breaking out of “pilot purgatory” to turn digital innovation into measurable impact. With a clear mandate to move beyond endless experimentation, the focus is on starting with a strong thesis, partnering intentionally, and scaling quickly when results are proven.

Rachel reflects on her journey from law to healthcare, bringing a unique lens on strategy, execution, and deal-making. She highlights the balance healthcare must strike that is moving fast in operational and administrative workflows while taking a deliberate, governance-led approach to clinical innovation. This “go slow to go fast” mindset enables both safety and speed.

She also underscores the growing role of AI in improving logistics, supporting care teams, and unlocking real-time insights, while emphasizing responsible deployment. Beyond technology, the real opportunity lies in connecting fragmented care journeys and extending care beyond hospital walls to create a more seamless, patient-centered experience. Through strategic investments and a focus on outcomes, Tampa General is building an innovation model designed to scale impact, not just ideas. Take a listen.

About Our Guest

Rachel Feinman is the Senior Vice President of Innovation, Ventures and Digital Solutions at Tampa General Hospital and the Managing Director of TGH Ventures, the innovation, investment and commercialization arm of the Tampa General Hospital system. In her role, Rachel leads innovation at TGH, including strategic partnerships focused on driving value creation for the system. Rachel also oversees the organization’s venture investment strategy, managing a portfolio of early-to-growth stage startups and sourcing additional opportunities.

Rachel has a passion for influencing strategy and driving the action that enables impactful innovation to truly transform the delivery of healthcare. She also enjoys working with and mentoring early-stage startups and emerging entrepreneurs, most recently having served as the Executive Director of the Florida-Israel Business Accelerator, an organization focused on helping high impact Israeli startups penetrate the U.S. healthcare market. Rachel is a fully recovered business attorney with a long career advising clients raising from private investment funds to startups to large corporate organizations. As an attorney, Rachel specialized in business transactions of all kinds, with a specialization in private equity and venture capital transactions, as well as intellectual property protection and technology licensing deals. Rachel also has varied philanthropic interests, serving on non-profit boards like the Gasparilla International Film Festival and the Florida Venture Forum. Rachel lives in Tampa with her husband Josh and her two sons, Asher and Ezra, as well as her stepson, Brooks. She enjoys traveling with her family, having quiet time at the beach and watching her sons play baseball.


Ritu: Hi everyone. Welcome to The Big Unlock podcast, and today we are really happy to have with us Rachel Feinman, a leader at Tampa General Hospital who’s helping shape the future of digital health innovation. She works at the intersection of clinical operations, digital transformation, and emerging technologies such as AI. And she brings a thoughtful perspective on how health systems can move from technology experimentation to real operational impact. And like we were talking about at HIMSS, get out of pilot purgatory. So really looking forward to having Rachel with us here today. And welcome to all our listeners. My name is Ritu Roy. I am the co-host of The Big Unlock podcast along with Rohit. I’ll ask Rohit to quickly introduce himself, and then it’s all yours, Rachel. Thank you for joining us today.

Rohit: Thank you, Rachel, and thank you, Ritu. I’m Rohit Mahajan. I’m the co-host of The Big Unlock Podcast along with Ritu and also the CEO at BigRio. So, super excited to have this conversation. And over to you, Rachel.

Rachel: Thank you so much for having me. I’m excited to be here to talk to you guys today. It’s funny, Ritu, you started talking about pilot purgatory, and at TGH we don’t do pilots. It was a mandate from our CEO, John Couris, after a lot of frustration with the fact that a lot of pilots are akin to a slow no, or an inability to show alignment or drive results. And so some of it’s a little bit tongue in cheek, I think, in terms of naming it a pilot versus something else, because of course we don’t just initiate everything at scale right away. Yeah. But the concept is we’re not going to be in the business of endless pilots. What we’re going to do is we’re going to start with a thesis. We’re going to identify a partner, a solution, start in a place where we think we can drive results, measure those results, and then if it works and it’s driving the results that we are anticipating and wanting to see, then we’re going to scale it quickly. We’re not going to stay in that purgatory that you were talking about. So I think it’s really important from a system perspective for us to think like that. Think about trying things, scaling quickly, driving impact, and really why we’re doing what we do. And it’s about impact.

Ritu: No, that’s great. Thank you, Rachel. I think the listeners would be really interested to hear your origin story because you have a very unusual background with law, and then you pivoted to healthcare. So we would love to hear how you got where you are and what it is that you really love doing about your job, and specifically about innovation.

Rachel: Sure. Yeah. This is something I love talking about because I think there are plenty of people who find themselves professionally feeling stuck or maybe feeling like they went down a path and they weren’t necessarily using all of the skills that they have, or experiencing kind of professional joy in what they’re doing, and that was really the case for me when I was practicing law. There’s so much about it that I like. I loved the people I worked with. I loved serving clients and helping them solve problems, something that I still do today, but there were a lot of aspects of it that I didn’t enjoy. Really, as an M&A and business lawyer, I always felt like the conversation with the lawyer ended right at the good parts. It was kind of like, just as they started talking about or thinking about strategy and solving operational challenges, I was like, okay, we’re charging by the minute — or, we’re getting charged by the minute — so we’re going to hang up with you now and go draft that document we talked about. For me, it was just that feeling like I was always being excused from the party right as the good parts were starting, and then realizing and connecting the fact that as a partner within a law firm, I was actually driving the strategy and some operational decisions within our law firm. But I wanted to do that as my full-time job. And at that time I was really engaged with startups in the startup ecosystem and here in Tampa. We’re really kind of part of that rise-of-the-rest mentality that I think took shape in the last decade or two, where innovation and startups can exist and be supported in places outside of Boston, New York, and Silicon Valley. So I guess it was probably 10 or so years ago, I started advising a number of startups, doing a lot of volunteering, and that led me to my first role outside of law, which was to stand up an accelerator program focused on Israeli companies that were looking to soft-land in Florida. And one of the verticals that we ultimately focused on was healthcare. And I was just fascinated by the challenges of building a health tech startup or a med device startup and selling into health systems like the one I currently work for. And so helping those startups was great, but I really felt limited in the ability to help them from the outside. And so I had the opportunity at the time — I’m a builder, I like building new things — and this was at the same time that our CEO had the vision to create an innovation and a venture function within Tampa General. So because I had gotten to know him, I somehow convinced him — I’m so happy I did that — that I could help stand up what’s now TGH Ventures and translate his vision into practice and build a team around all of it. And it’s just been so much fun. This industry that we’re in is plagued, fortunately or unfortunately, with endless challenges. It’s also an industry that touches every one of us as a patient or a family member. And so the opportunity to really dive in and solve challenges in an industry that I know touches everyone is really impactful. So I have fun every day.

Ritu: That’s an amazing origin story, and we are so happy you kind of combined all your skills. I think the lawyer path came in very handy when you were convincing, right? You have those skills to work.

Rachel: Yeah. I like to say I’m not officially a lawyer in my job, but I get to play one on a very frequent basis because we’re negotiating deals regularly with partners that we work with, and of course when we make our investments. So it definitely still comes in handy.

Ritu: Great. So Rachel, I would like to circle a little bit back to the pilots again because we were talking to somebody else and they made a very good point that with all these new innovations, especially with AI coming out, sometimes the mentality is, okay, fail fast and innovate. But in healthcare you’re like zero risk and you really have to look at the safety aspects of it, which leads to a very bipolar situation because these two things are so much at odds. And you talked about how at Tampa you’re not doing pilots and you really look for that scaling. So how do you kind of resolve or make those two meet in the middle? We would love to know.

Rachel: Yeah, that’s a great question, and I think you hit on the reason why, as an industry, we have in the past not moved as quickly. I mean, there are good reasons for it, right? When you’re talking about patient care and safety, and oftentimes the potential for medical errors and things that can have a really significant impact, of course you need to be incredibly safe and focus in on that. Fails around safety are not okay. Right? So when we talk about failing fast, which we do often, it’s really around the fact that there’s so much opportunity to improve the system and the logistics and the administrative and operational aspects of what we do even before you get to the idea of patient care or clinical care. So that’s not to say that there are not opportunities to innovate around that, and we do, and we touch aspects of clinical care, but I think that there absolutely are opportunities to recognize challenges and move fast as it relates to — I always think about it like we’re one giant logistics company, right? When we’re coordinating care of patients, whether it’s within the walls of a hospital or it is in that connective tissue between transactional visits for patients, there’s tons of opportunity for us to look at new care delivery models and new ways of leveraging technology to make scheduling more efficient. So I think moving fast in those areas, looking at what works, seeing successes, and then scaling those is absolutely doable. And then when it comes to aspects of safety and patient care, I always like to say the old expression: go slow to go fast. So in those instances, you start at the outset with the right governance, the right people around the table, but with the end goal of going fast in mind. And then I think you can get yourself out of those cycles of admiring things and getting hung up on what-ifs and what if this happened or that happened. Get all the right people around the table, go slow in the beginning to set the right guardrails to ensure safety. And then move fast to see if something is actually going to work and make a difference.

Rohit: I was thinking about the wonderful experience I had, Rachel, at the NEXT Summit, which was a very good learning experience and very energizing. Thank you for inviting us over there. Would you like to tell us more about what’s next for next year? And also, the report was crowdsourced, so I’m sure the audience would love to hear how that was done as well.

Rachel: Yeah, sure. I’d love to share a little bit about that. So this was our very first year putting on our NEXT Summit, and really we settled on calling it NEXT because we’re focused on driving what’s next in our industry, really around innovating the business aspects of healthcare. And so we brought together around 300 attendees, made up of leaders from within our organization, investors, other health system executives, politicians, payers, folks who are involved in retail healthcare, and academia. So we had a very robust and varied audience coming together across two days to talk about and hear: what can we do? Our goal was to really be solution-oriented. A lot of times you go to some of these conferences or you hear panelists, and it’s a lot of griping about what’s wrong with our industry, what are the problems. And I think we have to recognize and name those. But our goal was, and I think we achieved it with all of our discussions, to quickly move on from, here are all of our problems, to actually focusing on solutions. That was what we did. We are going to be having the NEXT Summit again in Tampa next year, again in February. We’re really excited about that. Of the 300 people who attended, almost half of them actually came from outside of the Tampa Bay area. So that was really great, to have done this the first time without really a proven product and with a lot of people not knowing what we were going to be doing. We had so many people travel in to participate, and it was really, really great. One of the key outputs, I think, Rohit, that you were alluding to was that we worked with a frequent partner of ours, Vu Studios, that’s focused and based here in Tampa. They’re incredible at the forefront of all things AI, and their expertise really is AI and digital and film, but they do a lot. They’ve got robust partnerships with Accenture and some other groups, including us. And so what we thought was, we’ve got all these incredible minds in healthcare for two days together in one space. How can we harness this great group of people to try to drive that change that we were talking about? So we brought Vu and their intelligence hub to bear. We had one of those little phone booths — I don’t know, Rohit, if you got in it.

Rohit: I did.

Rachel: Okay. It was great. But the goal was, let’s have the first AI-generated white paper from a conference. I don’t know if we were actually the first, but I think it was the first I’d heard of it, and no one else had told me that anyone else had done it. So we centered on a topic really near and dear to many of us, which is affordability. That’s a huge challenge in healthcare. We see healthcare costs continuing to rise. And what are we, as the leaders in this industry, going to do about it? So we put everyone together and we captured thousands of insights and were able to synthesize those, leveraging AI, and generate this white paper that we sent around and published on LinkedIn and other places while people were, frankly, probably still on their flights home. So the power of AI — really excited about it.

Rohit: It was almost in real time. Yeah, it was in real time.

Ritu: Yeah. I haven’t looked at it. I would love to read it. I’ll look it up now and find it.

Rohit: Yeah. So if I may ask one more question, Rachel. You mentioned how you set up the ventures at Tampa General Hospital. So could you tell us a little bit more about the lens or the screening process, or what your vision is with this venture? And so far, have you had any successes that you would like to talk about?

Rachel: Sure. Yeah. So we do a number of things, but one of the core things is we invest in emerging startups in healthcare as a health system venture arm. Our primary focus is on driving the strategy of the health system forward. So we do significant financial diligence. We want to make sure that the companies we are investing in, we feel confident about the likelihood of a strong financial return on those investments, but we are also very focused on whether or not that company is going to help us advance our strategy as a system in one way or another. And really more specific than just improving care or driving patient experience, we’re looking very specifically and tied into our organizational action plan, which drives our organization’s strategy and those specific tactics. So a good example of that is a company that we recently invested in called Reimagine Care. Unfortunately, I’ve lived this experience this past year with my own father, who was diagnosed with esophageal cancer, and he was a patient at TGH. Unfortunately, we hadn’t yet gone live with Reimagine Care, but it really crystallized for me going through the process of managing the complex health needs and symptoms of oncology patients who are going through chemo and immunotherapy. Just trying to understand and manage what is causing these symptoms at once — I mean, it’s like a puzzle. Trying to figure out and manage the care of these patients, and the burden on our care teams is significant in terms of the number of in-basket messages going to our doctors, the nurses answering the nurse care line. It’s not 24 hours a day. They stop answering the phones at a certain amount of time, and my mom knew that. She knew, okay, if I don’t hear back the answer to these questions by this certain amount of time, I’ve got to call again because I know the nurse line is closing. And what Reimagine Care does is leverage AI coupled with 24/7 clinical support to help these patients manage their care. And one of the key drivers for us is the number of admissions of our medical oncology patients in the ED. And you have very sick patients — the last place you need them to be is in the emergency room. So what Reimagine Care has been able to do at a number of institutions where they’re already live, and where we hope they’ll be able to drive the same outcomes for us, is drive up to a 70% reduction in avoidable emergency room visits for these oncology patients, improve the satisfaction of our patients, and also help eliminate the burnout of our providers. So that’s an example of a company that we’re invested in, and I think in the next few weeks we will be live with at TGH, helping patients like my dad who are battling cancer.

Rohit: That’s wonderful to hear.

Ritu: Yeah. Great story. Thank you for sharing that, Rachel. I mean, that really hits home when you have a personal anecdote to share. So Rachel, really interesting to hear about the report as well. Would you like to share, from all the research and the published report, are there any specific areas within healthcare that you feel are very underutilized, or where the real opportunities are, say in the next one to three years? Any advice for startups or people who are building? What do you think you would really love to see, or something you haven’t seen so far, and you feel that the market is ripe for that?

Rachel: Yeah, I mean, I hate to go where everyone goes around AI, but I mean, I have to. At TGH, we are deploying AI solutions at a rapid rate. I’m very excited about that. I’m very bullish on our opportunities to leverage AI across domains to be able to support our teams and our patients. So I think that’s one of the things. I think the other thing that’s really important, and folks who are building, I would encourage them to focus on, is that we still have opportunities to improve the way that we deliver care. More and more care is going into the home. More and more care is going to settings outside of the health system. And like I mentioned, that kind of fabric between transactions — we’re very focused on that as a system, not really being transactional with you and seeing you at these particular places, but how can we make sure that we thread all of those together for a seamless experience for you and, frankly, one that’s going to enhance your care, make sure nothing falls through the cracks, make sure all different care providers are communicating with one another, and you don’t feel like you’re in different specialist silos. I think there’s still a ton of opportunity to make an impact around that.

Ritu: Great. Thank you so much. I think we are almost at the end of time, so Rohit, would you like to ask any final questions?

Rohit: Yeah, sure. So Rachel, from a Tampa General Hospital perspective, would you like to share any big plans on expansion or new things that are happening over in your system?

Rachel: TGH is constantly growing. We just had a big announcement of our partnership on the east coast of Florida with Mass General. We’re really excited to be able to serve the east coast of Florida with that partnership and a growing network of specialists. We continue to grow and expand as a system in terms of our market as well as our research and our clinicians. There’s so much growth going on. I think we’re very excited about all of that.

Rohit: That was great to hear.

Ritu: Yeah.

Rachel: Well, thank you guys so much for having me.

Ritu: Thank you so much.

 

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

 

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

HIMSS 2026 Dispatch: Day 3 Reflections from the Floor

HIMSS 2026 Dispatch: Day 3 Reflections from the Floor

HIMSS 2026 Dispatch: Day 3 Reflections from the Floor

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

By the third day, a familiar rhythm begins to set in. The early-morning sessions, the steady flow of meetings, spontaneous hallway discussions, and those quick but meaningful connections that often lead to bigger ideas later.
And yet, the energy across HIMSS still feels as strong as Day 1.

The Power of Community at HIMSS

One of the most rewarding aspects of the day was continuing to meet people who recognize and follow The Big Unlock Podcast.

Over the years, the podcast has become a platform for conversations with healthcare leaders about digital transformation, AI adoption, and the realities of implementing innovation inside complex health systems. The goal has always been simple: learn directly from those building the future of healthcare and share those insights with the broader community.

At HIMSS, it’s incredibly gratifying to hear attendees say that the podcast helps them stay connected to what leaders across health systems, payers, and digital health companies are actually doing—not just what they are planning.

Several people also reached out expressing interest in joining us for Season 7, which is always exciting. HIMSS truly is one of the best places to discover new voices and fresh perspectives for the podcast.

AI Conversations Continue to Dominate

If there is one theme that has consistently dominated conversations throughout HIMSS 2026, it is artificial intelligence.

But the tone of the conversation has evolved.

Healthcare leaders are no longer just discussing the potential of AI—they are focusing on how to operationalize it at scale across clinical and operational workflows. Across the conference, discussions have centered on enterprise AI deployments, automation across hospital operations, and governance frameworks to ensure responsible adoption. 

In many ways, the industry appears to be moving beyond the hype cycle. Leaders are asking practical questions:

  • How do we integrate AI into clinical workflows without adding friction?
  • How do we govern AI responsibly while maintaining innovation speed?
  • How do we ensure AI actually reduces administrative burden for clinicians?

Those questions reflect a broader shift happening across healthcare. The focus is no longer simply about what AI can do, but about how it can create measurable impact inside real care environments

From AI Insights to AI Execution

Another theme emerging strongly this year is the rise of agentic AI systems—AI tools that can execute tasks across healthcare workflows rather than simply generating insights.

For example, new technologies showcased at HIMSS are exploring how AI agents can coordinate tasks across the revenue cycle, helping automate complex administrative processes. 

This represents a significant shift in how healthcare organizations think about automation. Instead of using AI solely for analytics or decision support, many organizations are exploring how intelligent systems can actively participate in operational processes—from patient engagement to clinical documentation to financial workflows.

It’s a trend that aligns closely with many of the conversations we’ve had on The Big Unlock Podcast with healthcare CIOs, CMIOs, and digital leaders.

Transformation Requires More Than Technology

Another important point that surfaced repeatedly during discussions at HIMSS is that technology alone will not transform healthcare.

Leaders emphasized that successful AI adoption requires workflow redesign, workforce engagement, and organizational change—not just new tools. 

In other words, healthcare transformation is as much about process and people as it is about technology.

That insight resonates deeply with what we hear from digital leaders across the industry. The organizations that succeed with AI are the ones that approach it not as a technology project, but as a strategic transformation initiative.

The Value of Conversations Between Sessions

One thing I’ve learned over the years attending HIMSS is that some of the most valuable insights come outside the official sessions.

Day 3 was full of those moments—quick introductions that turned into longer conversations, reconnecting with past podcast guests, and meeting innovators working on fascinating new ideas in digital health.

These interactions are what make HIMSS special. With tens of thousands of healthcare leaders gathered in one place, the conference becomes a powerful forum for sharing ideas and accelerating collaboration across the industry. 

Looking Ahead

As we move toward the final day of HIMSS 2026, I’m reflecting on how much the conversation around healthcare technology has matured.

AI is no longer just an exciting possibility. It is rapidly becoming a core capability that health systems are actively integrating into care delivery, operations, and patient engagement.

At the same time, the industry is becoming more thoughtful about governance, trust, and responsible implementation—ensuring that innovation ultimately benefits both clinicians and patients.

Until next time at HIMSS27, signing off here as Ritu M. Uberoy. And if you have a story about digital transformation, AI implementation, or healthcare innovation, do get in touch with us. At The Big Unlock Podcast we would love to hear it—and maybe feature you on a future episode.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

HIMSS 2026 Dispatch: Day 2 Reflections from the Floor

HIMSS 2026 Dispatch: Day 2 Reflections from the Floor

HIMSS 2026 Dispatch: Day 2 Reflections from the Floor

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Our second day at HIMSS 2026 continued the incredible momentum we felt on Day 1. As part of our ongoing HIMSS blog series, it has been energizing to see how many conversations across the conference are centered on the same themes we explore regularly on The Big Unlock Podcast—AI adoption, operational transformation, and the evolving role of technology in healthcare.

Day 2 delivered exactly what makes HIMSS such an important gathering for the industry: meaningful encounters, thoughtful discussions, and a shared sense that healthcare transformation is accelerating.

A Memorable Moment: Meeting Judith Faulkner

One of the most memorable moments of the day was meeting Judith Faulkner during a book signing at the Taylor & Francis Group bookstore.

For anyone working in healthcare IT, Judith Faulkner has had a profound impact on how digital health infrastructure has evolved over the past several decades. Through Epic Systems, she helped shape the electronic health record landscape that today supports clinical operations at many of the world’s leading health systems.

Meeting her was a special moment—one of those instances where you’re reminded that the digital transformation of healthcare has been built through years of vision, persistence, and innovation from leaders who pushed the industry forward.

Conversations That Reflect an Industry Shift

Beyond that highlight, Day 2 was packed with conversations across the exhibit halls and meeting spaces. What stood out most was how consistently the dialogue is evolving.

Just a few years ago, the focus at HIMSS was heavily centered on data infrastructure and interoperability. Today, the conversations are increasingly about how that data is being activated through AI to drive measurable operational and clinical outcomes.

Several themes surfaced repeatedly:

AI is moving beyond experimentation.
Health systems are increasingly looking to operationalize AI solutions across care delivery and administrative workflows.

Workflow integration is critical for scale.
AI tools that live outside core clinical systems rarely gain traction. The industry is now focused on embedding intelligence directly into workflows.

Automation is becoming operational.
From patient engagement and care coordination to revenue cycle and clinical documentation, organizations are exploring how AI can actively execute tasks—not just generate insights.

These themes echo many of the conversations we’ve had with healthcare leaders on The Big Unlock Podcast. Across nearly 200 episodes, one lesson has remained consistent: technology creates value when it improves workflows and enables care teams to focus on patients.

The Big Unlock Conversations at HIMSS

It was also wonderful to meet several podcast listeners and past guests throughout the day.

For those unfamiliar, The Big Unlock Podcast explores how healthcare leaders are driving digital transformation across health systems, payers, digital health companies, and life sciences organizations. Each conversation focuses on real-world experiences—what worked, what didn’t, and what others can learn.

At HIMSS, many attendees shared that they rely on the podcast to stay connected to emerging trends in healthcare AI, digital health, and innovation. Hearing that kind of feedback is incredibly rewarding for our team.

If you’re attending HIMSS this week and have a story about how your organization is implementing AI, advancing digital transformation, or tackling complex operational challenges, we would love to connect and potentially feature you on an upcoming episode.

AI, GenAI, and the Next Phase of Healthcare Transformation

Another clear takeaway from Day 2 is how rapidly the AI conversation is evolving.

Healthcare organizations are no longer just asking whether to adopt AI. The question now is how to scale it responsibly and effectively across clinical and operational environments.

We’re seeing increasing interest in areas such as:

  • AI-powered patient engagement and outreach
  • Intelligent clinical documentation and workflow automation
  • Predictive analytics for operational optimization
  • Agentic AI systems that can coordinate tasks across healthcare workflows

This shift—from analytics to AI-powered execution—represents a meaningful turning point in the industry.

Why HIMSS Still Matters

One of the things I appreciate most about HIMSS each year is that the most valuable insights often come from informal conversations rather than formal presentations.

The hallway discussions, quick introductions, and spontaneous meetings often spark the most interesting ideas. Day 2 was filled with exactly those moments—reconnecting with colleagues, meeting new innovators, and hearing firsthand how organizations are tackling some of healthcare’s most complex challenges.

Despite the scale of the conference, there is a real sense of community here. Everyone is working toward the same goal: improving healthcare through better technology, smarter processes, and stronger collaboration.

On to Day 3

As our HIMSS blog series continues, I’m looking forward to another day of learning, connecting, and capturing insights from leaders shaping the future of healthcare.

If you’re here at HIMSS 2026, please stop us if you see Rohit Mahajan or me—we’d love to meet you. And if you have a story worth sharing about AI, digital transformation, or healthcare innovation, let’s talk.

More reflections from the HIMSS floor coming soon as we move into Day 3.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

HIMSS26 Day 1: The Energy of AI-Driven Healthcare Transformation

HIMSS26 Day 1: The Energy of AI-Driven Healthcare Transformation

HIMSS26 Day 1: The Energy of AI-Driven Healthcare Transformation

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

There’s something special about the first day at HIMSS Global Health Conference & Exhibition 2026. The moment you step onto the floor, you can feel the collective energy of thousands of healthcare leaders, innovators, clinicians, and technologists all focused on one question: How do we transform healthcare through technology?

This year’s conference, taking place March 9–12 in Las Vegas, has brought together the global health IT ecosystem—from providers and payers to startups, investors, and technology companies—creating an unparalleled environment for learning, collaboration, and discovery.

AI Is Moving from Insight to Action

One of the dominant themes today has been the evolution of AI in healthcare—from tools that simply generate insights to technologies that actually execute workflows and drive outcomes.

Across sessions and conversations, leaders are asking practical questions:

  • How do we operationalize AI within clinical and administrative workflows?
  • How do we move from pilots to enterprise adoption?
  • How can AI augment—not replace—healthcare professionals?

This is where we’re seeing a new generation of technologies emerge—AI agents and automation platforms that actively participate in care coordination, patient engagement, and operational processes.

The conversation is shifting from “What can AI analyze?” to “What can AI actually do?”

The Rise of Intelligent Healthcare Operations

Another clear takeaway from Day 1 is that health systems are under enormous pressure to do more with less—address workforce shortages, improve access, and reduce administrative complexity.

Technology leaders are increasingly exploring solutions that:

  • Automate patient outreach and engagement
  • Improve operational efficiency across clinical workflows
  • Enable data-driven decision making
  • Support scalable digital transformation initiatives

In many ways, HIMSS has always been about the intersection of healthcare, technology, and operational transformation—but this year the urgency feels stronger than ever.

Healthcare organizations are not just exploring digital transformation anymore.

They are actively building AI-powered operating models.

Why HIMSS Still Matters

One of the reasons HIMSS remains such a powerful gathering is the sheer scale of collaboration it enables.

The conference brings together tens of thousands of health IT professionals, executives, innovators, and solution providers, along with hundreds of educational sessions and technology showcases. 

But beyond the sessions and the expo floor, what makes this event truly valuable are the conversations happening in hallways, networking events, and spontaneous meetings.

These conversations often spark the ideas that shape the next wave of healthcare innovation.

The Big Unlock Conversations at HIMSS

At The Big Unlock podcast, we’ve spent years speaking with healthcare leaders about the technologies shaping the future of the industry—from AI and data platforms to digital health innovation.

Day 1 at HIMSS has already reinforced a few important themes we’ve been seeing across the market:

  • Generative AI is becoming enterprise infrastructure
  • Agentic AI will power the next generation of healthcare workflows
  • Data platforms and interoperability remain foundational
  • Innovation increasingly requires collaboration between startups and health systems

Many of the most exciting conversations today have centered on how organizations can bridge the gap between cutting-edge AI innovation and real clinical or operational impact.

That’s where companies like BigRio focus—helping healthcare organizations design, build, and scale AI-driven digital solutions that solve real problems.

Looking Ahead to the Rest of the Week

If Day 1 is any indication, HIMSS26 will be a week filled with meaningful conversations about the future of healthcare technology.

I’m particularly excited about:

  • Emerging discussions around AI agents in healthcare
  • Innovations in digital health platforms and data interoperability
  • Conversations with leaders who are actually implementing AI at scale

And of course, connecting with colleagues, partners, and innovators who are all working toward the same goal: building a smarter, more accessible healthcare system.

If you’re attending HIMSS this week, I’d love to connect. These events are where ideas turn into collaborations—and collaborations turn into innovation.

More reflections from HIMSS26 coming soon.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

Heading to HIMSS 2026 with The Big Unlock Podcast

Heading to HIMSS 2026 with The Big Unlock Podcast

Heading to HIMSS 2026 with
The Big Unlock Podcast

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Over the years, hosting The Big Unlock Podcast has given us the opportunity to speak with some of the most forward-thinking leaders across health systems, digital health companies, payers, and life sciences organizations. These conversations have explored how emerging technologies—from AI and generative AI to automation and digital platforms—are transforming healthcare delivery and patient outcomes.

HIMSS is one of those rare moments where many of these ideas, conversations, and relationships come together in one place.

Continuing the Conversation at HIMSS

At HIMSS Global Health Conference & Exhibition 2026, Rohit and I are looking forward to meeting healthcare leaders, innovators, entrepreneurs, and technology partners who are shaping the next phase of digital transformation in healthcare.

The themes we often explore on The Big Unlock Podcast—AI adoption, operational transformation, data-driven healthcare, and the rise of intelligent automation—are front and center at HIMSS this year. It’s always energizing to see how quickly the industry continues to evolve and to hear directly from the people building these solutions.

Many of our podcast guests over the years are also part of the HIMSS community, and I’m excited to reconnect with them in person while also meeting new leaders who are pushing the boundaries of what’s possible in healthcare technology.

Let’s Connect at HIMSS

If you’re attending HIMSS Global Health Conference & Exhibition 2026, I would love to connect with you. Whether you’re a longtime listener of The Big Unlock Podcast, a healthcare executive exploring AI and digital transformation, or a founder building the next breakthrough in digital health, please feel free to reach out or stop me if you see me at the conference.

Events like HIMSS remind me why these conversations matter. Innovation in healthcare happens when people come together to share ideas, challenge assumptions, and collaborate on solutions that can truly improve care delivery.

I’m looking forward to an inspiring week of conversations, learning, and new connections.

And if you happen to see Ritu M. Uberoy or Rohit Mahajan at the conference, please do come say hello—we would love to meet you.

See you at HIMSS Global Health Conference & Exhibition 2026!

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

HIMSS26 Day 1: The Energy of AI-Driven Healthcare Transformation

HIMSS26 Day 1: The Energy of AI-Driven Healthcare Transformation

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

There’s something special about the first day at HIMSS Global Health Conference & Exhibition 2026. The moment you step onto the floor, you can feel the collective energy of thousands of healthcare leaders, innovators, clinicians, and technologists all focused on one question: How do we transform healthcare through technology?

This year’s conference, taking place March 9–12 in Las Vegas, has brought together the global health IT ecosystem—from providers and payers to startups, investors, and technology companies—creating an unparalleled environment for learning, collaboration, and discovery.

AI Is Moving from Insight to Action

One of the dominant themes today has been the evolution of AI in healthcare—from tools that simply generate insights to technologies that actually execute workflows and drive outcomes.

Across sessions and conversations, leaders are asking practical questions:

  • How do we operationalize AI within clinical and administrative workflows?
  • How do we move from pilots to enterprise adoption?
  • How can AI augment—not replace—healthcare professionals?

This is where we’re seeing a new generation of technologies emerge—AI agents and automation platforms that actively participate in care coordination, patient engagement, and operational processes.

The conversation is shifting from “What can AI analyze?” to “What can AI actually do?”

The Rise of Intelligent Healthcare Operations

Another clear takeaway from Day 1 is that health systems are under enormous pressure to do more with less—address workforce shortages, improve access, and reduce administrative complexity.

Technology leaders are increasingly exploring solutions that:

  • Automate patient outreach and engagement
  • Improve operational efficiency across clinical workflows
  • Enable data-driven decision making
  • Support scalable digital transformation initiatives

In many ways, HIMSS has always been about the intersection of healthcare, technology, and operational transformation—but this year the urgency feels stronger than ever.

Healthcare organizations are not just exploring digital transformation anymore.

They are actively building AI-powered operating models.

Why HIMSS Still Matters

One of the reasons HIMSS remains such a powerful gathering is the sheer scale of collaboration it enables.

The conference brings together tens of thousands of health IT professionals, executives, innovators, and solution providers, along with hundreds of educational sessions and technology showcases. 

But beyond the sessions and the expo floor, what makes this event truly valuable are the conversations happening in hallways, networking events, and spontaneous meetings.

These conversations often spark the ideas that shape the next wave of healthcare innovation.

The Big Unlock Conversations at HIMSS

At The Big Unlock podcast, we’ve spent years speaking with healthcare leaders about the technologies shaping the future of the industry—from AI and data platforms to digital health innovation.

Day 1 at HIMSS has already reinforced a few important themes we’ve been seeing across the market:

  • Generative AI is becoming enterprise infrastructure
  • Agentic AI will power the next generation of healthcare workflows
  • Data platforms and interoperability remain foundational
  • Innovation increasingly requires collaboration between startups and health systems

Many of the most exciting conversations today have centered on how organizations can bridge the gap between cutting-edge AI innovation and real clinical or operational impact.

That’s where companies like BigRio focus—helping healthcare organizations design, build, and scale AI-driven digital solutions that solve real problems.

Looking Ahead to the Rest of the Week

If Day 1 is any indication, HIMSS26 will be a week filled with meaningful conversations about the future of healthcare technology.

I’m particularly excited about:

  • Emerging discussions around AI agents in healthcare
  • Innovations in digital health platforms and data interoperability
  • Conversations with leaders who are actually implementing AI at scale

And of course, connecting with colleagues, partners, and innovators who are all working toward the same goal: building a smarter, more accessible healthcare system.

If you’re attending HIMSS this week, I’d love to connect. These events are where ideas turn into collaborations—and collaborations turn into innovation.

More reflections from HIMSS26 coming soon.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

HIMSS 2026 Dispatch: Day 2 Reflections from the Floor

HIMSS 2026 Dispatch: Day 2 Reflections from the Floor

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Our second day at HIMSS 2026 continued the incredible momentum we felt on Day 1. As part of our ongoing HIMSS blog series, it has been energizing to see how many conversations across the conference are centered on the same themes we explore regularly on The Big Unlock Podcast—AI adoption, operational transformation, and the evolving role of technology in healthcare.

Day 2 delivered exactly what makes HIMSS such an important gathering for the industry: meaningful encounters, thoughtful discussions, and a shared sense that healthcare transformation is accelerating.

A Memorable Moment: Meeting Judith Faulkner

One of the most memorable moments of the day was meeting Judith Faulkner during a book signing at the Taylor & Francis Group bookstore.

For anyone working in healthcare IT, Judith Faulkner has had a profound impact on how digital health infrastructure has evolved over the past several decades. Through Epic Systems, she helped shape the electronic health record landscape that today supports clinical operations at many of the world’s leading health systems.

Meeting her was a special moment—one of those instances where you’re reminded that the digital transformation of healthcare has been built through years of vision, persistence, and innovation from leaders who pushed the industry forward.

Conversations That Reflect an Industry Shift

Beyond that highlight, Day 2 was packed with conversations across the exhibit halls and meeting spaces. What stood out most was how consistently the dialogue is evolving.

Just a few years ago, the focus at HIMSS was heavily centered on data infrastructure and interoperability. Today, the conversations are increasingly about how that data is being activated through AI to drive measurable operational and clinical outcomes.

Several themes surfaced repeatedly:

AI is moving beyond experimentation.
Health systems are increasingly looking to operationalize AI solutions across care delivery and administrative workflows.

Workflow integration is critical for scale.
AI tools that live outside core clinical systems rarely gain traction. The industry is now focused on embedding intelligence directly into workflows.

Automation is becoming operational.
From patient engagement and care coordination to revenue cycle and clinical documentation, organizations are exploring how AI can actively execute tasks—not just generate insights.

These themes echo many of the conversations we’ve had with healthcare leaders on The Big Unlock Podcast. Across nearly 200 episodes, one lesson has remained consistent: technology creates value when it improves workflows and enables care teams to focus on patients.

The Big Unlock Conversations at HIMSS

It was also wonderful to meet several podcast listeners and past guests throughout the day.

For those unfamiliar, The Big Unlock Podcast explores how healthcare leaders are driving digital transformation across health systems, payers, digital health companies, and life sciences organizations. Each conversation focuses on real-world experiences—what worked, what didn’t, and what others can learn.

At HIMSS, many attendees shared that they rely on the podcast to stay connected to emerging trends in healthcare AI, digital health, and innovation. Hearing that kind of feedback is incredibly rewarding for our team.

If you’re attending HIMSS this week and have a story about how your organization is implementing AI, advancing digital transformation, or tackling complex operational challenges, we would love to connect and potentially feature you on an upcoming episode.

AI, GenAI, and the Next Phase of Healthcare Transformation

Another clear takeaway from Day 2 is how rapidly the AI conversation is evolving.

Healthcare organizations are no longer just asking whether to adopt AI. The question now is how to scale it responsibly and effectively across clinical and operational environments.

We’re seeing increasing interest in areas such as:

  • AI-powered patient engagement and outreach
  • Intelligent clinical documentation and workflow automation
  • Predictive analytics for operational optimization
  • Agentic AI systems that can coordinate tasks across healthcare workflows

This shift—from analytics to AI-powered execution—represents a meaningful turning point in the industry.

Why HIMSS Still Matters

One of the things I appreciate most about HIMSS each year is that the most valuable insights often come from informal conversations rather than formal presentations.

The hallway discussions, quick introductions, and spontaneous meetings often spark the most interesting ideas. Day 2 was filled with exactly those moments—reconnecting with colleagues, meeting new innovators, and hearing firsthand how organizations are tackling some of healthcare’s most complex challenges.

Despite the scale of the conference, there is a real sense of community here. Everyone is working toward the same goal: improving healthcare through better technology, smarter processes, and stronger collaboration.

On to Day 3

As our HIMSS blog series continues, I’m looking forward to another day of learning, connecting, and capturing insights from leaders shaping the future of healthcare.

If you’re here at HIMSS 2026, please stop us if you see Rohit Mahajan or me—we’d love to meet you. And if you have a story worth sharing about AI, digital transformation, or healthcare innovation, let’s talk.

More reflections from the HIMSS floor coming soon as we move into Day 3.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

HIMSS 2026 Dispatch: Day 3 Reflections from the Floor

HIMSS 2026 Dispatch: Day 3 Reflections from the Floor

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

By the third day, a familiar rhythm begins to set in. The early-morning sessions, the steady flow of meetings, spontaneous hallway discussions, and those quick but meaningful connections that often lead to bigger ideas later.
And yet, the energy across HIMSS still feels as strong as Day 1.

The Power of Community at HIMSS

One of the most rewarding aspects of the day was continuing to meet people who recognize and follow The Big Unlock Podcast.

Over the years, the podcast has become a platform for conversations with healthcare leaders about digital transformation, AI adoption, and the realities of implementing innovation inside complex health systems. The goal has always been simple: learn directly from those building the future of healthcare and share those insights with the broader community.

At HIMSS, it’s incredibly gratifying to hear attendees say that the podcast helps them stay connected to what leaders across health systems, payers, and digital health companies are actually doing—not just what they are planning.

Several people also reached out expressing interest in joining us for Season 7, which is always exciting. HIMSS truly is one of the best places to discover new voices and fresh perspectives for the podcast.

AI Conversations Continue to Dominate

If there is one theme that has consistently dominated conversations throughout HIMSS 2026, it is artificial intelligence.

But the tone of the conversation has evolved.

Healthcare leaders are no longer just discussing the potential of AI—they are focusing on how to operationalize it at scale across clinical and operational workflows. Across the conference, discussions have centered on enterprise AI deployments, automation across hospital operations, and governance frameworks to ensure responsible adoption. 

In many ways, the industry appears to be moving beyond the hype cycle. Leaders are asking practical questions:

  • How do we integrate AI into clinical workflows without adding friction?
  • How do we govern AI responsibly while maintaining innovation speed?
  • How do we ensure AI actually reduces administrative burden for clinicians?

Those questions reflect a broader shift happening across healthcare. The focus is no longer simply about what AI can do, but about how it can create measurable impact inside real care environments

From AI Insights to AI Execution

Another theme emerging strongly this year is the rise of agentic AI systems—AI tools that can execute tasks across healthcare workflows rather than simply generating insights.

For example, new technologies showcased at HIMSS are exploring how AI agents can coordinate tasks across the revenue cycle, helping automate complex administrative processes. 

This represents a significant shift in how healthcare organizations think about automation. Instead of using AI solely for analytics or decision support, many organizations are exploring how intelligent systems can actively participate in operational processes—from patient engagement to clinical documentation to financial workflows.

It’s a trend that aligns closely with many of the conversations we’ve had on The Big Unlock Podcast with healthcare CIOs, CMIOs, and digital leaders.

Transformation Requires More Than Technology

Another important point that surfaced repeatedly during discussions at HIMSS is that technology alone will not transform healthcare.

Leaders emphasized that successful AI adoption requires workflow redesign, workforce engagement, and organizational change—not just new tools. 

In other words, healthcare transformation is as much about process and people as it is about technology.

That insight resonates deeply with what we hear from digital leaders across the industry. The organizations that succeed with AI are the ones that approach it not as a technology project, but as a strategic transformation initiative.

The Value of Conversations Between Sessions

One thing I’ve learned over the years attending HIMSS is that some of the most valuable insights come outside the official sessions.

Day 3 was full of those moments—quick introductions that turned into longer conversations, reconnecting with past podcast guests, and meeting innovators working on fascinating new ideas in digital health.

These interactions are what make HIMSS special. With tens of thousands of healthcare leaders gathered in one place, the conference becomes a powerful forum for sharing ideas and accelerating collaboration across the industry. 

Looking Ahead

As we move toward the final day of HIMSS 2026, I’m reflecting on how much the conversation around healthcare technology has matured.

AI is no longer just an exciting possibility. It is rapidly becoming a core capability that health systems are actively integrating into care delivery, operations, and patient engagement.

At the same time, the industry is becoming more thoughtful about governance, trust, and responsible implementation—ensuring that innovation ultimately benefits both clinicians and patients.

Until next time at HIMSS27, signing off here as Ritu M. Uberoy. And if you have a story about digital transformation, AI implementation, or healthcare innovation, do get in touch with us. At The Big Unlock Podcast we would love to hear it—and maybe feature you on a future episode.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

Turning AI Hype into Healthcare Execution

Season 7

Episode 197 - Podcast with Aditya Bansod, CTO & Co-Founder, Luma Health - Turning AI Hype into Healthcare Execution

The Big Unlock
The Big Unlock
Turning AI Hype into Healthcare Execution
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In this episode, Aditya Bansod, CTO and Co-Founder of Luma Health, discusses why healthcare AI often underdelivers, and what leaders must do to turn promise into performance.

Aditya argues that AI’s challenge in healthcare isn’t ambition, but execution. While new tools are emerging rapidly, most remain point solutions that fail to integrate into the complex workflows that move patients from scheduling to care delivery. True impact, he says, depends on orchestrating the “last mile” of healthcare, referrals, intake, documentation, and the countless operational handoffs that determine whether care actually happens.

He shares how Luma approaches AI adoption with flexible guardrails, allowing health systems to calibrate automation based on confidence thresholds and maturity. The conversation also explores the rise of agentic AI, the tension between human-in-the-loop oversight and autonomy, and why CIOs are navigating a messy but necessary consolidation phase.

Looking ahead, Aditya is optimistic that AI will transform patient access and engagement, only if it’s deeply embedded into workflows, not layered on top of them. Take a listen.

About Our Guest

Aditya Bansod is CTO and co-founder of Luma Health. With a lifelong passion for building software, Bansod leads Luma Health’s technical vision and strategic direction for building a platform that empowers healthcare providers to better serve their patients and improve healthcare outcomes. With over 15 years of experience as a product management leader developing mobile solutions at Adobe and Microsoft, and at venture-backed start-ups, Bansod made the transition from B2B software solutions to healthcare in 2015 in order to have a meaningful and measurable impact on how providers use mobile technologies to engage with and communicate with their patients.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Day 3 at ViVE 2026: Conversations That Carry Forward

Day 3 at ViVE 2026: Conversations That Carry Forward

Day 3 at ViVE 2026: Conversations That Carry Forward

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 3 at ViVE 2026 in Los Angeles was a powerful close to four days of learning, sharing, and connection. What stood out most wasn’t just the innovations on display or the sessions we attended, but the quality of conversations and the real-world perspectives shared by peers, leaders, and innovators across healthcare

One of the highlights of today for me was the opportunity to showcase insights from The Big Unlock Podcast — a space where we’ve been exploring how healthcare leaders are actually operationalizing digital transformation, AI, and workflow change to deliver measurable impact. It was energizing to see how many people at ViVE are thinking deeply about what works, not just what’s new

Wrapping Up with Purpose

Day 3 wasn’t just the final day — it was a moment to reflect on how ideas shared earlier in the week are being translated into action:

The Big Unlock stories on stage and off
Today’s interactions reminded me why we started the podcast: to amplify honest conversations about how leaders are tackling complexity with clarity — whether that’s embedding AI into clinical workflows, improving patient experience, or enabling teams with practical tools and strategies. Hearing people at ViVE talk about these insights or referencing real-world examples was deeply rewarding. 

Meaningful hallway and roundtable discussions
ViVE’s unique mix of structured sessions and open dialogue continues to be its greatest strength. Day 3 was a testament to the power of connection — from impromptu discussions about workflow integration to deeper exchanges on governance, trust, and the human dimensions of technology adoption. 

What’s emerging — beyond the buzz
Across the final conversations of the event, a few themes stood out:

  • AI with purpose — not just innovation for its own sake, but AI that helps clinicians, supports judgment, and reduces friction
  • Workforce-centered design — solutions that meet teams where they work and help amplify their impact rather than replace it. 
  • Collaboration over competition — genuine partnerships between health systems, startups, payers, and technology partners that seek shared, measurable outcomes. 

Closing Thoughts

As ViVE 2026 comes to a close, what stays with me most isn’t a single demo or a single session — it’s the collective sense of urgency and purpose in the community. Leaders here aren’t just talking about transformation — they’re making it happen, even when the path is complex and the stakes are high. 

If you were here too, thank you for the conversations, the curiosity, and the commitment to what’s next in healthcare. And for those who couldn’t make it — let’s keep the dialogue going. There’s momentum to carry forward, and real work to be done.

Here’s to turning insight into impact — now, and throughout the year ahead. For continued conversations, connect with me on LinkedIn.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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Day 2 at ViVE 2026: From Insight to Action

Day 2 at ViVE 2026: From Insight to Action

Day 2 at ViVE 2026: From Insight to Action

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 2 at ViVE 2026 in Los Angeles was packed with energy, ideas, and accelerated conversations about the real work of healthcare transformation. After an inspiring opening day, today was all about digging deeper — exploring concrete approaches to emerging challenges, connecting with fresh perspectives, and prioritizing how we move from concept to measurable action.

The exhibit halls, session rooms, and networking spaces were buzzing with dialogue — not just about “what’s next,” but about how leaders are getting done what matters most in care delivery, workforce enablement, and intelligent technology adoption. 

Conversations That Matter: Workforce, Nurses, and Tech

One of the themes that stood out for me today was the focus on the healthcare workforce as an essential partner in innovation, particularly how technology can support clinicians rather than sideline them. From sessions exploring nursing’s evolving role in a tech-enabled future to practitioner stories about adoption barriers, the message was clear: technology must be designed with people at the center. 

This shift, from technology for technology’s sake to technology that solves real problems, is not just rhetoric. It was reflected in the questions attendees asked, the solutions showcased on the floor, and the collaborations forming in the hallways.

Practical Insights from Sessions and Demos

Day 2 brought a slew of engaging discussions and demos that underscored the practical side of healthcare innovation:

🔹 Operationalizing AI with Purpose
AI was everywhere; not just as a buzzword, but as a tool leaders are actively deploying to improve workflows, enhance patient experience, and support clinical decision-making. Conversations went beyond theory into use cases that reduce administrative burden and elevate care delivery.

🔹 Security, Trust, and Responsible Innovation
In a landscape where data powers everything from predictive insights to real-time clinical support, several thought leaders reiterated how security and trust aren’t optional — they’re foundational to sustainable transformation. 

🔹 Human-Centered Design in Action
The best sessions weren’t simply about “what tech can do,” they were about how organizations bring nurses, physicians, and patients into design conversations. That alignment is critical to creating solutions that people will actually use and benefit from. 

Meaningful Meetings That Extend the Day

Beyond the formal agenda, Day 2 was rich with curated and serendipitous conversations with health system leaders, innovators, and fellow practitioners. Whether we explored AI adoption strategies or debated how to reimagine patient-facing digital experiences, these exchanges reinforced a simple truth: transformation thrives at the intersection of diverse perspectives, deep expertise, and practical curiosity.

Looking Ahead with Momentum

As we wrap Day 2 and look toward the final day of ViVE 2026, the urgency to translate insight into impact is stronger than ever. We’re seeing more healthcare organizations that aren’t waiting for the perfect moment, they’re building it. They’re operationalizing solutions, elevating clinicians through technology, and centering real user needs in every conversation. 

If you’re at ViVE as well, I’d love to connect. We’re exploring AI in action, talking workforce empowerment, or simply capturing the momentum this community is creating. There’s so much opportunity for meaningful progress ahead. If you want to connect after the event because your calendar is full, feel free to drop me a note on LinkedIn.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Event Gallery

Day 1 at ViVE 2026: Energized, Inspired, and Focused on What’s Next

Day 1 at ViVE 2026: Energized, Inspired, and Focused on What’s Next

Day 1 at ViVE 2026: Energized, Inspired, and Focused on What’s Next

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 1 of ViVE 2026 in Los Angeles did not disappoint. I couldn’t be more excited about what’s unfolding at this incredible intersection of healthcare leadership, innovation, and digital transformation.

We kicked off the day with a bright, sunny California morning that matched the energy and optimism in the halls of ViVE. From the moment I stepped onto the event floor, with sessions underway, conversations buzzing, and new ideas in motion, it was clear that this year’s ViVE is a convergence of purpose and possibility.

Seeing Healthcare Innovation in Action

ViVE brings together health system and payer leaders, technology innovators, investors, and solution partners, all focused on transforming healthcare, not in theory, but in practice. This is where strategy meets execution, where real-world challenges get real-world solutions.

One of the highlights for me today was seeing how AI and digital technologies are being mobilized across the care continuum. From patient experience to clinical workflows, the narrative has shifted from “what might be possible” to “what’s already happening.” In the AI and digital health conversations I’ve engaged in, the focus is deeply anchored in augmenting people, improving outcomes, and removing friction from care delivery.

Connecting Through The Big Unlock Podcast

I’m also delighted to share that The Big Unlock Podcast continues to be featured in the ViVE Healthcare Podcast lists at the Media Village — a welcome acknowledgment of the meaningful dialogues we’ve been fostering with health system and industry leaders. Roaming the exhibit floor and seeing peers engage with the podcast’s themes — from workflow-first AI adoption to clinician-centric innovation — reminds me why we started this journey in the first place.

These aren’t abstract discussions. These are conversations about how AI and digital technologies can tangibly improve access, efficiency, and outcomes in care, grounded in the realities health leaders face every day.

What’s Been Top of Mind on Day 1

Here’s what’s stood out today:

🔹 AI Isn’t Just a Trend, It’s Becoming the Backbone of Healthcare Innovation
Across sessions and hallway conversations, AI is being talked about in terms of productivity, clinician support, and patient impact, and not just hype. There’s a palpable excitement around solutions that deliver measurable value and integrate seamlessly into how care teams operate. 

🔹 Digital Transformation Conversations Are More Practical and Immediate
Leaders are focusing on where technology intersects with workflow and culture, not only what it can do in the future. This practical lens, rooted in real operational and clinical needs, signals that the next phase of digital innovation is here.

🔹 Connection, Collaboration, and Community Matter
ViVE is a reminder that transformation doesn’t happen in isolation. It happens through shared insight, honest conversation, and bridging perspectives across the healthcare ecosystem.

Looking Ahead

As I reflect on Day 1, I’m energized by the momentum and the commitment I’ve seen from leaders across organizations. Whether we’re talking about AI that augments clinician judgment, digital tools that streamline patient access, or frameworks that support responsible technology adoption, the theme is clear: healthcare’s future is being built now, here at ViVE.

I look forward to more conversations, more insights, and more breakthroughs as the event continues. If you’re here too, let’s connect. There’s so much more to explore together.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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What Does Responsible AI Adoption in Healthcare Really Look Like?

What Does Responsible AI Adoption in Healthcare Really Look Like

Insights by Dr. Amit Phull, Chief Clinical Experience Officer, Doximity

In a recent episode of The Big Unlock podcast, Dr. Amit Phull, Chief Clinical Experience Officer at Doximity sat down with hosts Rohit Mahajan, and Ritu M Uberoy, both Managing Partners at BigRio and Damo, to answer a question that’s becoming harder and more urgent every day, “What does responsible AI adoption in healthcare really look like when you move beyond the hype and headlines?”

Dr. Phull’s perspective is grounded in the realities of clinical work. He’s an emergency medicine physician, with academic roles at Northwestern and George Washington University. He has also spent the last decade-plus building technology with one of the most clinician-centered platforms in healthcare.

What makes the conversation valuable is that it doesn’t treat “responsible AI” as an abstract principle. It treats it as an implementation discipline.

Throughout the podcast, Dr. Phull repeatedly returns to a simple pragmatic truth, clinicians adopt what helps them, trust what they can verify, and reject anything that feels like “one more thing.”

As he explained to Ritu “From the clinician perspective, ease of use is paramount… Being able to trust the technology is paramount as well… If they can’t trust the output… or god forbid it adds time to their day… it’s going to be very, very difficult to compel those clinicians to actually pick up that piece of software and leverage it.”

That one statement is basically a responsible adoption blueprint.

Let’s break down what Dr. Phull says responsible AI adoption looks like through the lens of workflow, trust, education, and the coming shift toward Agentic AI.

A Clinician-First Origin Story: “Build with Us” Is the Operating Model

Dr. Phull shared a helpful origin story, not just about himself, but about how Doximity’s approach evolved. He explained that Doximity was founded in 2010 with an initial mission to “rewire healthcare,” specifically by building tools that help physicians be more productive so they can provide better care. He noted that Doximity’s CEO and co-founder Jeff Tanney previously built Epocrates, which helped anchor the company in practical clinician utility from day one.

Dr. Phull’s own path mirrors that bridge between domains. He describes a “prior life” as a computer engineer, and how he’s spent his career living at the intersection of medicine and technology. That intersection is the key implementation detail to how Doximity builds successful AI tools – with physician involvement.

He explained how he first joined the company through a Physician Advisory Panel, where clinicians volunteer time to beta test tools and provide direct feedback on what should be built next. That same model continues to this day, including their upcoming 2026 medical advisory board, where clinician input shapes product direction.

This matters because according to Dr. Phull, responsible AI adoption isn’t just about “what the model can do,” it’s about whether clinicians see themselves in the design, and whether the tool feels like it understands the realities of care delivery.

 

In Healthcare, Adoption Starts With Ease of Use and Dies with Added Time

A core theme of the conversation is that clinicians are not resistant to innovation, they are resistant to burden. Dr. Phull explains that if a tool is difficult to use, or worse, if it adds time to the day, that added burden makes adoption nearly impossible.

This is where he makes a sharp comparison to EHRs.

“I would view EHRs as an interesting counter example. If EHRs were deployed not as they were, as part of a government rollout with mandates, I think there would’ve been an extreme increase in the amount of difficulty that it took all of us to adopt that sort of technology.”

Even today, after years of implementation, many clinicians still experience EHRs as a workflow tax. So, when Dr. Phull talks about AI adoption metrics, he points to signals that reflect real-world use:

  • recurrent use
  • increased use
  • time savings
  • burnout (as a proxy for clinician welfare)

And he pairs those “hard metrics” with the lived outcomes that actually motivate adoption.

“Just by being able to go home for that additional hour… doctors… can have dinner with their families or be a little bit more human outside of the practice of medicine.”

That is an operational definition of value.

Responsible AI adoption, in this framing, is not about novelty, It’s about time returned to clinicians, and friction removed from the day.

 

Medical Education Can Use AI—But It Must Protect Clinical Reasoning

Dr. Phull also speaks as a faculty member, and his comments here are especially relevant to “responsible AI adoption” because adoption isn’t only about today’s clinicians.

It’s about the next generation. He describes AI as a “double-edged sword” in training environments. AI can empower young clinicians, but it can also allow them to “skip a step,” bypassing the hard work of developing critical thinking.

The most memorable line in this section is his emphasis on maintaining a “spidey sense,” or the value of human intuition.

“It’s very important that clinicians still develop and maintain a ‘spidey sense.’ We do not want to reduce clinicians to being messenger pigeons in terms of looking up information and then kind of handing that off to their patients in regards to advancing their care.”

So, what’s the responsible approach in training?

He describes allowing use of tools (including Doximity GPT) but requiring trainees to justify their thinking in real time.

“Medicine cannot be reduced to… a book report… You actually have to demonstrate an understanding of the validity and the context…”

This is a key insight for leaders building responsible AI programs inside health systems:

For Dr. Phull, AI literacy isn’t just “how to use the tool,” It’s how to interrogate outputs, apply judgment, and sustain clinical reasoning.

 

AI Could Actually Return Humanity to the Practice of Medicine

He concludes in an interesting way, “In a very paradoxical way, the [AI robots] actually reintroduce humanity to the practice of medicine.”

He describes the emotional frustration clinicians express through a common phrase:

“I didn’t go to medical school to be a data entry clerk…”

Then he paints a picture of what responsible adoption could enable; “When I enter a patient’s room, I can shake their hand, look them straight in the eye, put my hands on my patient… while the documentation, the coding… is taken care of.”

 

The Takeaway

Dr. Amit Phull’s view of responsible AI adoption is practical and clinician centered. His message is clear; healthcare doesn’t need more AI excitement or “one-off” pilots that never stick. It needs tools clinicians can actually trust and use; tools that reduce friction, return time, and protect clinical judgment rather than replace it. In his framing, responsible adoption happens when AI is built with clinician input, grounded in security and verifiability, and supported by human review where it matters most. The organizations that lead won’t be the ones chasing the newest model. They’ll be the ones that make AI dependable in the real world because their workflows, safeguards, and adoption strategy are designed for trust at scale.

Dr. Phull brings a clinician-operator lens to responsible AI adoption. His insights are especially useful because they translate “responsible AI” from principle into practice:

  • Ease of use is the gateway to adoption—clinicians won’t tolerate tools that add steps, context switching, or time.
  • Trust is built through verifiability: HIPAA compliance, rigorous security, and AI outputs anchored in citations.
  • Human clinical review can be a product feature, not just a governance afterthought—Peer Check is a concrete model.
  • Medical education must protect clinical reasoning—trainees can use AI, but they must justify thinking and build a real “spidey sense.”
  • The most realistic future is a middle path: AI that augments clinicians, reduces burnout, and expands access to care.
  • The best version of Agentic AI may be paradoxical: by removing admin burden, it can “reintroduce humanity” to medicine.

Heading to ViVE 2026 in Los Angeles

Heading to ViVE 2026 in Los Angeles

Heading to ViVE 2026 in Los Angeles

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

I’m heading to ViVE 2026 in Los Angeles (Feb. 22–25) — one of the largest gatherings of health systems and payer organizations — and I’m truly looking forward to it.

Every year, ViVE brings together leaders who are shaping the future of healthcare — from health system executives and payer innovators to digital health founders and investors. It’s a unique opportunity to step away from day-to-day demands and focus on what’s ahead: AI, digital transformation, interoperability, value-based care, and the evolving patient experience.

What excites me most is the chance to learn. I’m looking forward to attending sessions that go beyond theory and focus on practical implementation — what it really takes to move from pilot programs to enterprise scale. Healthcare is at an inflection point. AI and automation are no longer experimental; they are becoming embedded in access, operations, and care delivery. The question is not whether we adopt these technologies — but how we do so responsibly and effectively.

As Co-Host of The Big Unlock Podcast, I’m also excited to connect with leaders who are willing to share candid insights. My focus is always on practical insight: how healthcare leaders are navigating innovation, scaling technologies like AI and GenAI responsibly, and driving measurable outcomes within their organizations. These are the kinds of conversations that move our industry forward, beyond hype, and into real, sustainable impact. The most valuable conversations are often the honest ones: the lessons learned, the challenges faced, and the strategies that drive measurable impact.

And of course, I’m looking forward to reconnecting with long-time colleagues and forming new relationships. Healthcare transformation is a team effort, and gatherings like this remind us that progress happens through collaboration.

If you’re attending #ViVEvent, let’s connect. Whether it’s between sessions or over coffee, I’d love to meet, exchange perspectives, and continue building toward a smarter, more connected healthcare ecosystem.

Looking forward to learning, listening, and building together.

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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Day 1 at ViVE 2026: Energized, Inspired, and Focused on What’s Next

Day 1 at ViVE 2026: Energized, Inspired, and Focused on What’s Next

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 1 of ViVE 2026 in Los Angeles did not disappoint. I couldn’t be more excited about what’s unfolding at this incredible intersection of healthcare leadership, innovation, and digital transformation.

We kicked off the day with a bright, sunny California morning that matched the energy and optimism in the halls of ViVE. From the moment I stepped onto the event floor, with sessions underway, conversations buzzing, and new ideas in motion, it was clear that this year’s ViVE is a convergence of purpose and possibility.

Seeing Healthcare Innovation in Action

ViVE brings together health system and payer leaders, technology innovators, investors, and solution partners, all focused on transforming healthcare, not in theory, but in practice. This is where strategy meets execution, where real-world challenges get real-world solutions.

One of the highlights for me today was seeing how AI and digital technologies are being mobilized across the care continuum. From patient experience to clinical workflows, the narrative has shifted from “what might be possible” to “what’s already happening.” In the AI and digital health conversations I’ve engaged in, the focus is deeply anchored in augmenting people, improving outcomes, and removing friction from care delivery.

Connecting Through The Big Unlock Podcast

I’m also delighted to share that The Big Unlock Podcast continues to be featured in the ViVE Healthcare Podcast lists at the Media Village — a welcome acknowledgment of the meaningful dialogues we’ve been fostering with health system and industry leaders. Roaming the exhibit floor and seeing peers engage with the podcast’s themes — from workflow-first AI adoption to clinician-centric innovation — reminds me why we started this journey in the first place.

These aren’t abstract discussions. These are conversations about how AI and digital technologies can tangibly improve access, efficiency, and outcomes in care, grounded in the realities health leaders face every day.

What’s Been Top of Mind on Day 1

Here’s what’s stood out today:

🔹 AI Isn’t Just a Trend, It’s Becoming the Backbone of Healthcare Innovation
Across sessions and hallway conversations, AI is being talked about in terms of productivity, clinician support, and patient impact, and not just hype. There’s a palpable excitement around solutions that deliver measurable value and integrate seamlessly into how care teams operate. 

🔹 Digital Transformation Conversations Are More Practical and Immediate
Leaders are focusing on where technology intersects with workflow and culture, not only what it can do in the future. This practical lens, rooted in real operational and clinical needs, signals that the next phase of digital innovation is here.

🔹 Connection, Collaboration, and Community Matter
ViVE is a reminder that transformation doesn’t happen in isolation. It happens through shared insight, honest conversation, and bridging perspectives across the healthcare ecosystem.

Looking Ahead

As I reflect on Day 1, I’m energized by the momentum and the commitment I’ve seen from leaders across organizations. Whether we’re talking about AI that augments clinician judgment, digital tools that streamline patient access, or frameworks that support responsible technology adoption, the theme is clear: healthcare’s future is being built now, here at ViVE.

I look forward to more conversations, more insights, and more breakthroughs as the event continues. If you’re here too, let’s connect. There’s so much more to explore together.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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Day 2 at ViVE 2026: From Insight to Action

Day 2 at ViVE 2026: From Insight to Action

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 2 at ViVE 2026 in Los Angeles was packed with energy, ideas, and accelerated conversations about the real work of healthcare transformation. After an inspiring opening day, today was all about digging deeper — exploring concrete approaches to emerging challenges, connecting with fresh perspectives, and prioritizing how we move from concept to measurable action.

The exhibit halls, session rooms, and networking spaces were buzzing with dialogue — not just about “what’s next,” but about how leaders are getting done what matters most in care delivery, workforce enablement, and intelligent technology adoption. 

Conversations That Matter: Workforce, Nurses, and Tech

One of the themes that stood out for me today was the focus on the healthcare workforce as an essential partner in innovation, particularly how technology can support clinicians rather than sideline them. From sessions exploring nursing’s evolving role in a tech-enabled future to practitioner stories about adoption barriers, the message was clear: technology must be designed with people at the center. 

This shift, from technology for technology’s sake to technology that solves real problems, is not just rhetoric. It was reflected in the questions attendees asked, the solutions showcased on the floor, and the collaborations forming in the hallways.

Practical Insights from Sessions and Demos

Day 2 brought a slew of engaging discussions and demos that underscored the practical side of healthcare innovation:

🔹 Operationalizing AI with Purpose
AI was everywhere; not just as a buzzword, but as a tool leaders are actively deploying to improve workflows, enhance patient experience, and support clinical decision-making. Conversations went beyond theory into use cases that reduce administrative burden and elevate care delivery.

🔹 Security, Trust, and Responsible Innovation
In a landscape where data powers everything from predictive insights to real-time clinical support, several thought leaders reiterated how security and trust aren’t optional — they’re foundational to sustainable transformation. 

🔹 Human-Centered Design in Action
The best sessions weren’t simply about “what tech can do,” they were about how organizations bring nurses, physicians, and patients into design conversations. That alignment is critical to creating solutions that people will actually use and benefit from. 

Meaningful Meetings That Extend the Day

Beyond the formal agenda, Day 2 was rich with curated and serendipitous conversations with health system leaders, innovators, and fellow practitioners. Whether we explored AI adoption strategies or debated how to reimagine patient-facing digital experiences, these exchanges reinforced a simple truth: transformation thrives at the intersection of diverse perspectives, deep expertise, and practical curiosity.

Looking Ahead with Momentum

As we wrap Day 2 and look toward the final day of ViVE 2026, the urgency to translate insight into impact is stronger than ever. We’re seeing more healthcare organizations that aren’t waiting for the perfect moment, they’re building it. They’re operationalizing solutions, elevating clinicians through technology, and centering real user needs in every conversation. 

If you’re at ViVE as well, I’d love to connect. We’re exploring AI in action, talking workforce empowerment, or simply capturing the momentum this community is creating. There’s so much opportunity for meaningful progress ahead. If you want to connect after the event because your calendar is full, feel free to drop me a note on LinkedIn.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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Day 3 at ViVE 2026: Conversations That Carry Forward

Day 3 at ViVE 2026: Conversations That Carry Forward

By Ritu M. Uberoy

Co-Host, The Big Unlock Podcast

Day 3 at ViVE 2026 in Los Angeles was a powerful close to four days of learning, sharing, and connection. What stood out most wasn’t just the innovations on display or the sessions we attended, but the quality of conversations and the real-world perspectives shared by peers, leaders, and innovators across healthcare

One of the highlights of today for me was the opportunity to showcase insights from The Big Unlock Podcast — a space where we’ve been exploring how healthcare leaders are actually operationalizing digital transformation, AI, and workflow change to deliver measurable impact. It was energizing to see how many people at ViVE are thinking deeply about what works, not just what’s new

Wrapping Up with Purpose

Day 3 wasn’t just the final day — it was a moment to reflect on how ideas shared earlier in the week are being translated into action:

The Big Unlock stories on stage and off
Today’s interactions reminded me why we started the podcast: to amplify honest conversations about how leaders are tackling complexity with clarity — whether that’s embedding AI into clinical workflows, improving patient experience, or enabling teams with practical tools and strategies. Hearing people at ViVE talk about these insights or referencing real-world examples was deeply rewarding. 

Meaningful hallway and roundtable discussions
ViVE’s unique mix of structured sessions and open dialogue continues to be its greatest strength. Day 3 was a testament to the power of connection — from impromptu discussions about workflow integration to deeper exchanges on governance, trust, and the human dimensions of technology adoption. 

What’s emerging — beyond the buzz
Across the final conversations of the event, a few themes stood out:

  • AI with purpose — not just innovation for its own sake, but AI that helps clinicians, supports judgment, and reduces friction
  • Workforce-centered design — solutions that meet teams where they work and help amplify their impact rather than replace it. 
  • Collaboration over competition — genuine partnerships between health systems, startups, payers, and technology partners that seek shared, measurable outcomes. 

Closing Thoughts

As ViVE 2026 comes to a close, what stays with me most isn’t a single demo or a single session — it’s the collective sense of urgency and purpose in the community. Leaders here aren’t just talking about transformation — they’re making it happen, even when the path is complex and the stakes are high. 

If you were here too, thank you for the conversations, the curiosity, and the commitment to what’s next in healthcare. And for those who couldn’t make it — let’s keep the dialogue going. There’s momentum to carry forward, and real work to be done.

Here’s to turning insight into impact — now, and throughout the year ahead. For continued conversations, connect with me on LinkedIn.

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

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Augmenting Care and Strengthening Trust with AI

Season 7

Episode 196 - Podcast with Dr. Andrea Willis, SVP & Chief Medical Officer, BlueCross BlueShield of Tennessee - Augmenting Care and Strengthening Trust with AI

The Big Unlock
The Big Unlock
Augmenting Care and Strengthening Trust with AI
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In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care.

From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation.

Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For her, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.

About Our Guest

Dr. Andrea Willis is senior vice president and chief medical officer for BlueCross BlueShield of Tennessee, which has more than 6,500 employees and serves more than 3.3 million members throughout the state and across the country. She oversees total health management and pharmacy management and is responsible for achieving and maintaining clinical quality excellence, optimizing member care and medical management functions, oversight of clinical risk management and collaboration with the provider community.

Willis previously served as medical director of the BlueCross CHOICES Long-Term Services and Supports (LTSS) program. She also served as medical director for BlueCare Tennessee and Cover Tennessee.

Before joining BlueCross, Willis was director of the CoverKids program and was responsible for developing Tennessee’s federally approved State Children’s Health Insurance Program (SCHIP). She also previously served as deputy commissioner for the Tennessee Department of Health.

Willis is a fellow with the American Academy of Pediatrics. She earned a Master of Public Health from Johns Hopkins Bloomberg School of Public Health and a Doctor of Medicine from Georgetown University School of Medicine. She received her Bachelor of Science degree from the University of Alabama at Birmingham.

She was recognized by Modern Healthcare as one of its Women Leaders of 2024. Additional past honors from the magazine include her being named as one of its Top 25 Minority Executives in Healthcare and one of the 50 Most Influential Clinical Executives. Johns Hopkins Alumni Association honored her with a Distinguished Alumna Award. Becker’s Hospital Review named her as an African-American Leader in Healthcare to Know. She received the inaugural Champion of Healthcare Award in Diversity, Equity and Inclusion awarded by the Chattanooga Times-Free Press in 2021.

Willis has testified in front of the U.S. Senate Committee on Health, Education, Labor, and Pensions. She served as a member of the Health Advisory Board for the Johns Hopkins Bloomberg School of Public Health and the Nashville Health Care Council. She is currently President of the Board for the Middle Tennessee Chapter of the American Heart Association.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

How Is AI Transforming Clinical Trials and Drug Discovery

AI is having a transformative impact on the pharmaceutical industry. The use of AI tools is dramatically accelerating clinical trials the drug discovery process by drastically cutting time and costs through predictive modeling, virtual screening, automated labs, identifying novel targets, predicting compound properties and even repurposing existing drugs, making the process faster, more efficient, and personalized by analyzing vast biological datasets to find better candidates and pathways.

On a recent episode of The Big Unlock podcast Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging & Pathology at Merck Research Laboratories sat down with host Rohit Mahajan, Managing Partner at BigRio and Damo to discuss how AI is improving drug discovery and the challenges that still remain.

Dr. Goldmacher first discussed how we all know that clinical trials are very expensive and time-consuming and how there are many ways that AI can reduce both of those burdens. “AI essentially improves efficiency, which means it can accelerate every aspect of a clinical trial. In the preclinical phase, AI is being used for things like genome searches and for target identification. When it comes to drug design it can help assess molecular protein interactions and things of that nature, and in the clinical space there’s a lot of use of AI to support clinical operations. That includes things like creating documents, protocols, clinical study reports, informed consent forms, reports of various kinds.”

He went on to discuss that in every clinical trial there is a massive amount of data that gets collected and manual review of all that data is extremely labor intensive. He explained to Rohit that both “traditional AI” and newly introduced “AI agents” can absolutely help sort through this enormous amount of data for targeted analysis.

AI, Drug Discovery and Endpoints

Dr. Goldmacher described endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective.  As he told Rohit, “Endpoints are measurements. Drug trials require accurate measurements to make decisions. AI allows us to make better measurements for better decisions. He went on to illustrate with an example from his own background in medical imaging.

“Let’s take cancer as an example. The traditional way of assessing whether a cancer drug is working in a clinical trial is that you do a scan, let’s say a CT scan before treatment starts. You identify the tumors, and you pick out a few of them that you’re going to measure. Imaging continues over the course of the trial, and if the measurements shrink, that’s called a response. That’s good if they increase, that’s called progression, which is bad. What you do at each assessment point is apply a mathematical algorithm to each tumor you are tracking to determine if you are getting a complete response, a partial response or no response or progression. Then you look at all those responses, and you extract an endpoint such as objective response rate or progression-free survival based on established criteria.”

He then discussed where AI comes in, particularly when it comes to medical imaging. He explained to Rohit that in those initial scans, there is a lot of information that isn’t immediately visible to the naked eye. AI models can see patterns, pixel patterns that indicate a lot more than just how big a tumor is, but its microbiology, such as invasive vascularity or necrosis, any number of things that are not appreciable with the eye, but can be measured by a model and tracked via AI that can look for those patterns and assess a drugs specific effectiveness on a specific immuno-oncology response and not merely if a tumor has grown or not.

“In that initial scan traditionally, you are only measuring size and using that as your endpoint. There is so much more info there that could make for a more efficient trial, however human analysis of those scans to determine the tumor microenvironment is extremely expensive and time consuming -for radiologists — but not for AI.”

 

What the Future Holds for AI and Drug Discovery

Despite the obvious increases in efficiency that AI tools can bring to clinical trials, Dr. Goldmacher cautioned that challenges remain, mostly surrounding Big Data and privacy issues.

He stressed that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, even the most sophisticated AI tools cannot deliver reliable results. As he concluded his interview with Rohit, Greg pointed to the FDA’s evolving guidance on AI and emphasized the need for rigorous validation before using AI-derived measurements for all regulatory decisions, but underscored that with thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen to the entire podcast here.

True AI Scalability in Healthcare Requires Integration and Cooperation

Insights by Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health

If you are a regular listener to “The Big Unlock” podcast, you will notice a bit of a pattern in our conversations about “AI in healthcare.” Many episodes are heavy on ambition, light on execution. They celebrate breakthroughs, but they skip the messy middle: the place where promising tools either become part of daily care or quietly fade out after a pilot.

That is what makes this recent episode where hosts Rohit Mahajan and Ritu M Uberoy, both Managing Partners at BigRio and Damo, sat down with Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, worth a listen!

The episode is not built around hype, demos, or speculative futurism. It is built around the operating truth that healthcare is not short on ideas. It is short on integration, adoption, and scalable implementation. Dr. Sathya’s ubique “center of gravity” is implementation. He explicitly frames himself as an implementation scientist who focuses on making ideas usable in real-world clinical environments, and he’s clear that this is where healthcare innovation succeeds or fails. 

The conversation stays anchored to what real clinicians will tolerate, what real systems can absorb, and what leaders must do to move beyond experimentation into repeatable operational value.

The Real Scalability Problem Isn’t the Model

The primary message that Dr. Sathya had was this, scalability is not primarily a model-performance question. It’s an implementation question. He explained, “Many organizations can find smart tools. Many can run pilots. Many can produce dashboards that look promising. But healthcare is a high-friction environment. The clinical day is full. The operational machine is complex.” He then added “one more thing is, it’s not neutral—it’s costly.

That’s why Dr. Sathya emphasizes a core scaling truth, “If it’s not built for clinicians… it’s not going to work. If AI isn’t designed for clinicians and doesn’t fit their workflow, it will fail to integrate and won’t scale.”

He went on to describe how “integration” and “scalability” are less about preference and more about physics. A tool that requires extra steps, extra context switching, or extra training becomes another load on already overloaded teams.

 

Integration Beats “Innovation Theater”

One of the most refreshing parts of the conversation is how plainly Dr. Sathya talks about integration. He describes a common failure pattern that many healthcare leaders will recognize immediately: a new tool arrives that requires clinicians to take on another app, another login, another workflow, another tab, another mental shift.

Even if it’s “good AI,” it’s still friction. As he said to Ritu, “If I have to download another app… it’s not integrated into my workflow.”

Dr. Sathya then explained that from his perspective and experience, the barrier is not just inconvenience. The barrier is that healthcare workflows are already dense, and clinicians are already managing multiple systems, constraints, and interruptions. An extra step doesn’t feel like “an extra step.” It feels like something that competes with patient care.

 

Ambient Documentation is a Proof Point for Scalable AI

As the conversation continued, Dr. Sathya offered ambient documentation as a good concrete example. Why? Because ambient documentation represents a category of AI that is scaling for a very clear reason, it solves a daily pain point and fits the natural flow of care.

He notes that ambient documentation can replace scribes for many clinicians. That matters operationally because scribes are often viewed as a practical relief valve for documentation load. If a tool can reduce that burden, the value is immediately understandable.

“Ambient listening is a great example of what I have been talking about. It works, it’s easy to use, it’s succeeding right now because it’s integrated into a lot of our workflows and that’s why it’s replacing scribes for a lot of clinicians.” 

Springboarding from this example, he went on to describe what scalable AI looks like in healthcare:

  • It removes a task clinicians already want removed.
  • It works in the background.
  • It fits the normal visit experience.
  • It produces value without requiring clinicians to become tool operators.

There’s also a lesson here for strategy. Dr. Sathya explained how many AI efforts target “advanced” clinical tasks first. But the fastest scaling opportunities are often the basic burdens—documentation, routing, scheduling, triage, and administrative work that eats time every day.

 

Scalability Requires Cooperation, Not Just “Buy-in”

Dr. Sathya also said that “cooperation” has to be a cornerstone of effective implementation and scalability. He explained to Rohit that even when a tool is effective, scaling it across a large health system requires alignment across multiple groups:

  • clinicians and clinical leadership
  • operations and workflow owners
  • IT, security, and infrastructure teams
  • compliance and governance
  • training and change management
  • sometimes revenue cycle and finance

A lack of cooperation produces predictable outcomes:

  • “local wins” that never spread
  • inconsistent practices
  • tool sprawl
  • duplication of effort
  • fragile adoption that fades when champions move on

In contrast, cooperation enables standardization: the ability to take what works in one place and make it repeatable across many sites.

This is why “AI scalability” is not only a technology initiative. It is an operating model initiative.

“If you want AI to scale, you need cooperation that is structural, not personal,” Dr. Sathya said. “Without cross-functional cooperation, the default outcome is fragmentation: pockets of use, inconsistent practices, and tool sprawl. With cooperation, AI becomes an operational asset rather than an IT experiment.”

 

The Next Wave: Agentic AI Will Raise the Stakes

As the interview drew to a close, Dr. Sathya predicts that more autonomous, “AI agents” AI will begin to take off, and he links that to workforce and operational implications.

“Agentic AI is going to take off, and I think that will significantly enhance our jobs. But it will also lead to some workforce disruptions that we will have to expect and be prepared for. How we train people and adapt to this next phase is going to be what this year is all about.”  

This is a key point for scale-minded leaders. The more autonomous the system becomes, the more important it becomes to define – what the system is allowed to do, where it must ask for approval, how it escalates exceptions, who monitors quality over time, and how accountability is assigned. 

Agentic AI will not scale safely through enthusiasm alone. It will scale where governance is mature, workflows are clear, and cooperation is strong.

 

The Takeaway – Scaling What Actually Works

Dr. Sathya’s message is refreshingly practical: healthcare doesn’t need more AI demos. It needs more integrated tools and more cooperative operating models. The organizations that win won’t be the ones with the most pilots. They’ll be the ones that can standardize, support, and spread what works—because their workflows, teams, and governance are built for scale. Dr. Sathya’s strong focus on practical innovation leaves you with a practical checklist based on his unique implementation lens.

 

  • AI doesn’t scale as an add-on. If it requires extra apps, extra steps, or extra friction, adoption fades fast.
  • “Built for clinicians” is the scaling requirement. Usability and workflow fit are not optional if you want sustained adoption.
  • Time saved drives adoption. In the real world, clinicians adopt what reduces burden and is easy to use.
  • Ambient documentation is a model example of scalable AI. It removes daily work and fits the natural visit flow.
  • AI can help solve evidence overload. It can reduce the burden of staying current by surfacing and digesting clinical information at scale.
  • Agentic AI will raise the bar for governance and workforce readiness. More autonomy means more need for clear boundaries, accountability, and cross-team alignment.

AI Must Strengthen a Clinician’s “Spidey Sense,” Not Replace It

Season 7

Episode 195 - Podcast with Dr. Amit Phull, Chief Clinical Experience Officer, Doximity - AI Must Strengthen a Clinician’s “Spidey Sense,” Not Replace It

The Big Unlock
The Big Unlock
AI Must Strengthen a Clinician’s “Spidey Sense,” Not Replace It
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In this episode, Dr. Amit Phull discusses what responsible AI adoption in healthcare really looks like, starting with trust, usability, and preserving clinician judgment. He emphasizes that ease of use and confidence in outputs are non-negotiable for clinician adoption, especially in already time-constrained workflows.

The discussion also explores why AI must be built with clinicians, not simply deployed for them, and how poorly integrated tools risk adding friction instead of value. Dr. Phull also talks about preserving a clinician’s “spidey sense”—the intuition developed through experience—while using AI to augment, not override, clinical judgment. The conversation also touches on how success should be measured beyond dashboards, including recurrent use, time savings, and reductions in burnout.

Dr. Phull states that AI, when designed thoughtfully, can help clinicians reclaim time, sharpen expertise, and focus more fully on patient care, without losing the human edge that defines great medicine. Take a listen.

About Our Guest

Dr. Amit Phull is Chief Clinical Experience Officer at Doximity, where he has helped shape the company’s physician-first strategy since 2014. A board-certified emergency medicine physician with a background in computer science, Dr. Phull brings a rare dual perspective: he is both a practicing clinician and a digital health executive leading AI product development at one of the most widely used platforms in U.S. medicine.

With decades of experience at the intersection of care delivery and technology, Dr. Phull plays a critical role in bridging the gap between clinical practice and product innovation. He has a front-row view of today’s healthcare AI arms race, and a hands-on role in building tools that deliver real clinical value. At Doximity, he works closely with engineers, data scientists, and fellow physicians to test, validate, and scale AI solutions that help care teams reclaim time, reduce burnout, and stay focused on what matters most: their patients.

Dr. Phull was instrumental in the development of Doximity’s telehealth platform during the COVID-19 pandemic, and today leads clinical strategy for the company’s growing suite of AI-powered tools, including its ambient scribe tool and evidence-based clinical reference DoxGPT. A longtime champion of Doximity’s “docs and dorks” mindset, he ensures that every innovation enhances – not disrupts – clinical workflows.

Dr. Phull holds an M.D. and a B.S. in Computer Science from the University of Virginia. He completed his emergency medicine residency at Northwestern University in Chicago, where he currently serves as adjunct faculty. He also holds a faculty appointment at the George Washington University School of Medicine and Health Sciences. Prior to his role at Doximity, Dr. Phull also worked at Bain & Company.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

What is the “Healthcare Trilemma” and How Can it Be Solved With AI?

The healthcare trilemma, sometimes also referred to as the “Iron Triangle,” describes the inherent trade-off between three core goals: Cost, Quality, and Access, first coined by William Kissick, the late University of Pennsylvania Wharton School Professor of Economics. The decades long dilemma has been that while it can be relatively easy to improve one or two aspects, it often comes at the expense of the third. For example, increasing access or quality often raises costs, while cutting costs can reduce quality or access, making it difficult to achieve all three simultaneously in a perfect system. Modern variations also include a fourth goal like health outcomes making it a “Quadruple Aim.”

But no matter what you call it, on a recent episode of The Big Unlock podcast Matthew Blosl, CEO of DexCare, sat down with hosts Rohit Mahajan, Managing Partner and CEO at BigRio and Damo, and Ritu M. Uberoy, Managing Partner at BigRio and Damo to share his insights on how focus, co-innovation and AI can be used to finally address this age-old issue.

A Culture of Co-Innovation

Solving all three legs of the Iron Triangle requires a certain amount of “co-innovation” particular when it comes to developing IT solutions for healthcare, however, as Matt explained, that is something that over the course of his career he saw as somewhat lacking. As he told Ritu, “Customization was often seen as a negative, particularly when you were dealing with SaaS solutions for healthcare. You created something, and it was just supposed to a ‘set and forget it’ kind of solution. But I found that kind of one size fits all approach just really could not work for the large healthcare systems I was working with.”  He went on to explain that you simply cannot adoption at scale nor reap the benefits that AI can bring, without customization and co-innovation.

“[Our job is to] innovate for a given health system. They all have different priorities. They all have different workflows. They all have different system and data capabilities, and so we look at innovation on an individual basis. We’re coming in and we’re helping innovate using obviously our core platform but making it specifically applicable to the environment in which we’re implementing it.

 

The Role of AI and the Challenge of Staying Focused

As our regular readers and listeners to our podcast know, healthcare is certainly at a nexus when it comes to AI, and Matt would certainly agree.

 “We are at a technological inflection point regarding AI implementation in healthcare.  It’s arguably the largest one we’ve seen. It’s the one that’s evolving at an unprecedented pace. Yet, what I find most interesting is that especially within healthcare, at first, there’s still a lot of apprehension around AI. Even though AI enables us to do things that we’ve never done before. It’s going to take a little bit of time to get health systems and healthcare in general comfortable with the risk associated with it.”

He then restated how “co-innovation,” again is the answer to overcoming such hesitations

“AI can deliver a lot of great things, but we really need to partner with our clients to help them understand how to do this. Getting healthcare to adopt new technologies has always been difficult and complex. There needs to be some level of empathy going beyond simply what the technology can provide.”

Yet, he admits that because AI has the power to do so many things well, it can cause companies like his to actually lose focus and try to use it to do too much.   

“There is so much that we can do to innovate within the AI space that it’s very easy for us to go outside of our lane very quickly. What we’re really trying to do at DexCare is stay focused, to simply do what we do, but use AI to do it that much better and thereby take our core strength – care orchestration – to a level that we and our clients in the industry never thought was possible.”

 

Solving the Healthcare Trilemma

Though similar in its challenges, Matt’s description of the healthcare trilemma as DexCare perceives it departs somewhat from Professor Kissick’s classic definition. For him, the legs of the triangle are: more patients, fewer practitioners, and smaller margins.

Interestingly enough, Matt believes that it may take a combination of three things to solve the trilemma: co-innovation, AI and focus.

He explained how solving the trilemma, basically how to do more for more patients with less staff and lower revenue, is the starting point of every conversation they have with a client.

“It starts with that empathy I mentioned earlier. We understand you have  a staffing issue, whether that be actual physicians, or nurses, and at the same time,  we see you are strained economically, and from there it’s very easy to apply co-innovation to look at the Dex Care platform and focus on how we can help.”

AI Succeeds Through Seamless Workflow Integration and Clinician Empowerment

Season 7

Episode 194 - Podcast with Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health - AI Succeeds Through Seamless Workflow Integration and Clinician Empowerment

The Big Unlock
The Big Unlock
AI Succeeds Through Seamless Workflow Integration and Clinician Empowerment
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In this episode, Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, unpacks why healthcare innovation only scales when clinicians, public health, and AI are designed to work together.

Dr. Sathya shares his journey from surgery to journalism to public health advocacy, including leading gun violence prevention efforts. He explains why most AI pilots fail, because of poor workflow integration and clinician burden, and why ambient intelligence, tele-specialty care, and agentic AI are poised to scale. His message is clear: build technology alongside clinicians, not around them. Take a listen.

About Our Guest

Chethan Sathya, MD, MSc is a pediatric surgeon, public health leader, journalist, and Vice President of Strategic Initiatives Northwell Health. He has received numerous awards and recognitions, including top 40 under 40 by Modern Healthcare, the Community Health Leadership award from the United Hospital Fund, and Top Rising Healthcare Leaders Under 40 by Becker’s Hospital Review. As Director of Northwell’s Center for Gun Violence Prevention, he spearheads an innovative, health system-wide approach to firearm injury prevention, integrating research, clinical screening, advocacy, and public health interventions. Dr. Sathya has received grants totaling more than $5 million and has published numerous peer reviewed papers that have helped significantly advance the fields of injury prevention, pediatrics, implementation science, and public health.

A National Institutes of Health (NIH)-funded researcher and reviewer, Dr. Sathya led the development of a pioneering universal screening protocol for firearm injury risk, through which over 100,000 families have been screened. He also founded the National Gun Violence Prevention Learning Collaborative, engaging over 600 healthcare institutions in evidence-based firearm injury prevention strategies. His leadership extends to national partnerships, including the Milken Institute (Senior Advisor), the Clinton Foundation, Sandy Hook Promise (Board of Directors), and White House-led health system convenings on gun violence prevention.

Beyond firearm injury prevention, Dr. Sathya has been at the forefront of public health and healthcare innovation. He has led system wide initiatives in health disparities, childhood disease prevention, social innovation, and value-based care, and has also worked closely with state and federal agencies and lawmakers to improve public health infrastructure, re-think private-public partnerships, and leverage unique aspects of social innovation to improve health outcomes. He also advises startups and major health tech firms on AI in medicine, digital health, and data-driven solutions. With expertise in implementation science, he focuses on scaling and sustaining innovative healthcare strategies.

A sought-after thought leader and surgeon-journalist, Dr. Sathya has contributed to CNN, Scientific American, The Washington Post,and TIME and has delivered keynotes at major forums including the World Economic Forum, Clinton Global Initiative, Milken Global, the White House, American Hospital Association and the National Academies of Sciences, Engineering, and Medicine. He also serves as Trauma Director at Cohen Children’s Medical Center, Associate Professor of Surgery and Pediatrics at the Zucker School of Medicine, and Affiliate Scientist at the University of Toronto. Dr. Sathya completed his undergraduate degree at McGill University, medical school and general surgery training at the University of Toronto, followed by a Pediatric Surgery Fellowship at Northwestern Medicine in Chicago. He holds a Master’s in Clinical Epidemiology from the University of Toronto and completed a Fellowship in Global Journalism at the Munk School of Global Affairs. Additionally, he pursued a Public Health program at the Dalla Lana School of Public Health and completed the Health Policy and Executive Leadership program at the Heller School for Social Policy and Management at Brandeis University.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Fixing Healthcare’s “Blind Men and the Elephant” Data Problem

Season 7

Episode 193 - Podcast with Jonathan Bush, Founder & CEO, Zus Health - Fixing Healthcare’s “Blind Men and the Elephant” Data Problem

The Big Unlock
The Big Unlock
Fixing Healthcare’s “Blind Men and the Elephant” Data Problem
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In this episode, Jonathan Bush, Founder & CEO of Zus Health, shares a bold vision for the next phase of healthcare transformation. Drawing on decades of experience, Jonathan argues that while EHR adoption is largely complete, today’s systems remain fee-for-service–oriented, creating fragmented views of patients – what he describes as the “blind men and the elephant” problem. The result: clinicians still lack a complete, longitudinal picture of the patient and rely on repeated tests and “bags full of records.”

Jonathan explains how Zus Health is re-architecting healthcare data by creating a longitudinal, always-on common patient record. Zus is an API-first platform built on an AI-enabled backbone that aggregates, structures, and continuously updates data across multiple EMRs. He emphasizes the power of network effects, where shared intelligence can eliminate redundant tests and unnecessary care.

The conversation also explores why interoperability must move beyond regulatory compliance to become core infrastructure for value-based care, and how AI-driven summarization and agentic workflows can reduce clinician burden while enabling proactive, patient-centered care. Take a listen.

About Our Guest

Jonathan Bush is founder and CEO of Zus Health, a company building the first shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care. He sits on the board of Innovaccer, and is the co-founder and former CEO of athenahealth and former Executive Chairman of Firefly Health.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI May Improve Healthcare Access, But Will Rural and Underserved Communities Trust It?

AI May Improve Healthcare Access, But Will Rural and Underserved Communities Trust It

AI is having a transformative impact on healthcare. The innovation AI has brought to diagnostics and advanced therapeutics cannot be understated. Another area that bears mentioning is the many ways that AI could improve access to quality healthcare, particularly in rural and underserved communities; however, many challenges remain.

Certainly, AI holds immense potential to bridge rural healthcare gaps via telehealth, faster diagnostics, and better resource management, tackling shortages and isolation. Nevertheless, significant hurdles remain, including poor broadband, low digital literacy, data privacy concerns, biased algorithms, and the high cost of implementation, demanding careful, inclusive strategies to avoid worsening disparities.

On a recent episode of The Big Unlock podcast Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, sat down with host Ritu M. Uberoy, Managing Partner at BigRio and Damo to share her insights on how her organization, and the federal government is addressing these issues.

For Underserved Communities it’s a Matter of Trust

Lisa noted that patients, particularly in rural areas are very used to “hands on” interaction with healthcare providers — when they can get to see one! Therefore, they are more comfortable with AI in back-office and diagnostic use cases compared to roles that feel like they are “replacing” clinicians.

As she told Ritu, “Our organization is really looking at improving the healthcare system and transforming it so that at the end of the day it works for everyday people in the United States.”

She went on to stress the need for rigorous listening, research, and language that resonates with people, so that the “patient’s voice” remains a big part of any program to bring healthcare AI into underserved communities.

“We’re following AI as sort of an issue from the patient and the everyday person’s perspective, and I think one of the things that’s occurred to us in the advocacy community is that the voice of patients and the voice of people is somewhat missing from the table right now.”

She went on to explain that when it comes to AI, her organization’s focus is not so much on technological innovation, but more on advocating for the patient in overcoming those trust issues, particularly in rural and underserved communities.


AI and Rural Health Transformation

Health inequities have long been a problem in America. Lisa discussed how the federal government’s Rural Health Transformation Program, introduced in July, 2025 is trying to change that.

The Rural Health Transformation Fund is something that I think many people are looking at as a real opportunity for doing something big to really bring solutions to the rural health infrastructure and make improvements so that rural health across the America can certainly live out its potential to address the needs of rural America.”

She went on to explain that the program represents a “real opportunity to inject new life in rural America when it comes to healthcare.” Continuing that the initiative is huge investment – $50 billion over the span of five years – and a good portion of that budget is allocated for infrastructure and AI.


Bridging the AI Trust Gap

Despite the investment and support of the current administration for rural health transformation, Lisa still sees bridging the trust gap as the greatest challenge rural communities face in leveraging the benefits AI can bring. She told Ritu that when it comes to AI, her organization’s research has found patients in rural communities are comfortable with back-office areas, or diagnostics, but have a fear of it replacing doctors.

Our initial research found that the closer that you get to introducing AI into situations where it seems it may be subverting or supplanting the actual physician in the room, that is when people [in these communities] become very uncomfortable.”

When asked by Ritu “what is the best way to address that gap?” Lisa said that she thinks it is going to require a lot more research. Stating that the goal is to look at specific positive use cases, ones that not only demonstrate the technological advances that AI brings to healthcare, but the cases that successfully integrate AI on behalf of patients, consumers and people.

What Does 2026 Hold for AI and Healthcare? A Look at the Year Ahead

What Does 2026 Hold for AI and Healthcare? A Look at the Year Ahead

Rohit Mahajan

“In the rapidly evolving landscape of healthcare, the integration of artificial intelligence (AI) is not just a possibility; it is an inevitability. As we stand on the brink of a new era, the potential of AI to revolutionize medicine is both exhilarating and daunting — and necessary!” says Edward Marx, CEO, Marx Advisory, in the Forward of my recently released new book, Generative AI Unlocking the Next Chapter in Healthcare.

Ed went on to say, “… the advent of AI represents a paradigm shift unlike any other. It promises not only to enhance existing practices but to redefine the very fabric of healthcare delivery and research. While some technologies of the past never lived up to their hype, AI is likely to exceed the hype as we continue to execute on its promises.”

As we close the calendar on 2025, let’s peer into that future and take a look at the trends we will be watching in AI in healthcare for 2026, all of which I myself and my co-author Ritu M Uberoy discuss extensively in the book.


Increased Adoption of GenAI

The transformative potential of Generative AI (GenAI) is becoming increasingly apparent across many sectors, but its impact on healthcare stands out as particularly revolutionary. GenAI refers to the use of machine learning models, such as Large Language Models (LLMs), which are designed to generate new data, including text, images, and even molecular structures, that can mimic or build upon existing information. These technologies are not only redefining how we think about artificial intelligence but are also paving the way for unprecedented advancements in medical care.

In healthcare, GenAI holds the promise of transforming everything from diagnostics and personalized treatment plans to drug discovery and patient care management. LLMs excel in natural language understanding and generation, allowing them to process vast amounts of unstructured data, such as medical records, research papers, and clinical trial results. This capability has already begun to change how healthcare professionals access and interpret complex medical information, leading to faster, more accurate decision-making.

The importance of GenAI in healthcare cannot be overstated. As the demands on healthcare systems continue to grow, driven by aging populations, rising healthcare costs, and the increasing complexity of diseases, GenAI offers scalable solutions that enhance both the efficiency and quality of care. GenAI models, for example, can analyse medical images, pathology slides, and genomic data with unmatched accuracy, enabling earlier detection of conditions such as cancer. Furthermore, they can simulate chemical interactions and design novel molecules, dramatically reducing the time and cost associated with drug development.

From interpreting medical images to discovering new drug compounds, GenAI is at the forefront of innovation, offering powerful tools that can significantly improve patient outcomes.


The Rise of Agentic AI

The next big trend to watch for in 2026 will be the increased deployment and implementation of “Agentic AI” solutions. The next “big thing” that is liable to go the same route as ambient listening is “Agentic-AI.” An AI Agent is a software system powered by artificial intelligence that can perform specific tasks autonomously, making decisions based on data and learning over time; in healthcare, AI agents are utilized to analyze patient data, automate administrative tasks, assist with diagnosis, recommend treatment plans, and generally streamline clinical workflows, allowing healthcare providers to focus on patient care by handling repetitive tasks.

The extraordinary aspect of AI Agents is autonomy. Rather than merely responding to inputs with canned answers, these agents can make incremental decisions, refine their reasoning as more data comes in, and even proactively identify potential issues that require human intervention. They also demonstrate deeper contextual awareness. An AI Agent assisting in a clinical decision-support scenario can pull a patient’s history, current vital signs, and relevant medical literature, then synthesize all of this information to propose diagnostic steps or treatment adjustments.


AI Voice Agents in Healthcare

A subset of Agentic AI is AI Voice Agents. Conversational voice agents are intelligent software systems that use GenAI to have natural, human-like conversations over the phone or via chat. However, do not confuse voice agents with “chatbots.” They are far more sophisticated, capable of handling complex dialogue, maintaining context, and providing personalized support 24/7.

Healthcare is not solely about clinical diagnostics and treatments; it is equally about effective communication, education, and patient adherence. This is where conversational voice agents are already making a substantial impact. They can bridge the gap between clinical encounters by responding to patient inquiries at any time, sending personalized medication reminders, or providing explanations of lab results in accessible language. When integrated with wearable devices, agents can track daily vital signs or activity levels, recognizing worrisome trends and alerting both the patient and healthcare professionals accordingly. Patients appreciate having round-the-clock access to a reliable, knowledgeable interface that offers consistent support and reassurance. By “speaking” multiple languages or adapting content to diverse cultural contexts, AI agents can also cater to patients who might otherwise struggle with traditional, English-only healthcare resources. In doing so, these systems bolster patient engagement and can lead to better adherence to treatment plans, which is increasingly important in value-based healthcare models.

What should we expect to see trending in Agentic AI and healthcare in the year ahead? Although many current AI agents remain primarily reactive, the shift toward proactive interventions seems inevitable. Instead of waiting for a patient’s call to flag worrisome symptoms or for a clinician to initiate a data query, next-generation agents will detect patterns in real time and alert stakeholders before a crisis unfolds. An agent might discern an emerging infection trend within a hospital unit by analyzing lab orders and patient vitals, then recommend proactive precautions or resource allocation. By predicting potential bottlenecks or imminent disease outbreaks, these systems could help healthcare organizations save valuable time and potentially even lives.


Where Will This All Take Us in 2026 and Beyond?

Generative Artificial Intelligence has emerged as a revolutionary force across healthcare, reshaping diagnostic tools, therapeutic pathways, administrative workflows, and drug discovery. As we peer into the horizon, the trajectory of GenAI in healthcare appears both exhilarating and complex.

The longevity of GenAI’s impact on medicine ultimately hinges on the sustained commitment of multiple stakeholders. Clinicians who interact with AI-driven systems must maintain a critical mindset, asking hard questions about algorithmic limitations. Healthcare administrators and policy leaders should continue refining frameworks that balance innovation with patient well-being. Researchers, whether in academia or industry, will push the boundaries of what is possible with generative models, from advanced protein folding to personalized vaccine development. Each of these efforts requires long-term funding, robust data infrastructures, and progressive educational initiatives that cultivate AI literacy among medical professionals.

Given the global scope of healthcare, international collaborations and data-sharing initiatives may prove decisive in accelerating advancements. By pooling resources, expertise, and diverse patient data sets, multinational coalitions could turbocharge the learning cycles of GenAI systems. Cross-border consortia have already begun forming around topics like cancer genomics and rare disease research. Incorporating GenAI into these collaborations will likely amplify the pace and scale of discoveries, especially if ethical considerations and equitable benefits remain part of the guiding principles.

One look at today’s headlines and it is easy to see that many Americans feel frustrated with a healthcare system that seems broken and plagued by systemic inefficiencies. The government, the private sector, and medical consumers themselves are spending so much on healthcare, and yet, average people are not reaping the benefits in better outcomes. Is generative AI a cure-all for all that is broken? No. But it can provide a lot of fixes in both the near and long term.


Want to Learn More?

You can also learn a lot more about GenAI and its impact on health care by reading the book in its entirety.

Co-authored with my colleague, Ritu M Uberoy, it explores the GenAI revolution in medicine and what it means for clinicians, researchers, innovators, and policymakers worldwide. Published by Taylor & Francis Group, the book is available NOW, in print and eBook formats through Amazon, Barnes & Noble, Taylor & Francis (ebook only) and other online retailers. For more information or to order your copy directly, visit the official authors’ webpage.

AI Improves Endpoints and Evidence in Clinical Trials

Season 6: Episode #192

Podcast with Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging & Pathology at Merck Research Laboratories

AI Improves Endpoints and Evidence in Clinical Trials

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In this episode, Dr. Greg Goldmacher, Associate VP of Clinical Research at Merck, known as MSD outside of the United States and Canada, explains how AI is transforming imaging, clinical trials, and early-stage drug development. Greg describes endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective. He notes that AI is not new to imaging and aligns well with pattern recognition, yet its real value lies in identifying details that humans often miss.

Greg stresses that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, AI cannot deliver reliable results. He also points to the FDA’s evolving guidance on AI and emphasizes the need for rigorous validation before using AI-derived measurements for regulatory decisions.

Greg highlights the opportunity to improve efficiency, reduce human burden, and generate more consistent insights. With thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen.

Video Podcast and Extracts

About Our Guest

Dr. Gregory Goldmacher is currently Associate Vice President in Clinical Research, and Head of Clinical Imaging & Pathology at Merck Research Laboratories. With his team of physicians and scientists he oversees the use of imaging and clinical pathology assessments in approximately 300 clinical trials across all therapeutic areas. In addition, he leads multi-disciplinary research efforts in artificial intelligence, tumor modeling, novel oncology response criteria, and other innovative approaches in drug development. He also supports business development, strategic venture investments, data standardization, and educational initiatives.

Prior to Merck, he was a senior medical director and Head of Oncology Imaging at ICON. He has held leadership positions in numerous collaborative groups across industry and academia focused on clinical trial methods, artificial intelligence, quantitative imaging, and data standards.

Greg received his bachelor’s degree from the University of Chicago, his MD and PhD in Neuroscience from the UT Southwestern Medical Center, and his MBA from Temple University’s Fox School of Business. He did his clinical training in diagnostic radiology, with fellowships in neuroscience and neuroimaging at the Massachusetts General Hospital and Thomas Jefferson University. He lives in the Boston area.


Rohit: Hi Greg, welcome to the Big Unlock podcast. It’s great to have you on the show today. Thank you for having me, Greg. Absolutely. I’m Rohit Mahajan. I’m the CEO of Damo Consulting and BigRio, a Boston-based consulting company. Damo does strategy consulting for healthcare providers and payers and works with several pharma companies on AI, data, and analytics initiatives. I think we are in for a treat with our listeners.

Greg: Thanks, Rohit, and thank you for having me. I understand that most of the time your focus is on healthcare, and biopharma is healthcare-adjacent. It has some crossover interest, so I appreciate the invitation to talk to your audience. My name is Greg Goldmacher. I am Associate VP of Clinical Research at Merck Research Laboratories and head of the Clinical Imaging and Pathology function. My team oversees the use of scans and tissue in assessing trial outcomes and clinical trial endpoints.

Rohit: As we all know, Greg, there are so many clinical trials at this point in time. I think the number is very large, possibly approaching a million. So what kind of clinical trials do you focus on with your group?

Greg: My group has a broad base, and we support trials across every therapeutic area. We go where the endpoints are. What is an endpoint? It is a measurement of whether a clinical trial has met its objective. You make a measurement in one group of trial participants, compare it with another group, and see whether you have shown safety and efficacy.

The majority of trials where clinical imaging is used for endpoints are in oncology. Intuitively, you can think about what you measure to see whether a cancer drug is working. Are tumors growing or shrinking over time? You assess that by doing a series of scans.

There are several hundred clinical trials my team supports. The large majority are in oncology, but we also support central nervous system, immunology, cardio-respiratory, metabolic disease, and other therapeutic areas.

Rohit: That is fantastic, Greg. From what I know about clinical trials, it is a long and expensive process because patients are involved. It is usually a big hurdle for biopharma companies to complete clinical trials in a way that allows the drug to go to market. Could you tell us a little more, for listeners who may not be aware of this long and expensive process, about how this works at a high level?

Greg: Yeah, sure. I have to preface everything by saying I am speaking on behalf of myself. I am not speaking on behalf of Merck, and I will not discuss any specific Merck products, programs, or trials. I will speak broadly about biopharma, the processes, and then we can get into the use of technology and AI.

So let’s start with the big picture. There is the preclinical process where molecules are designed, evaluated for molecular properties, first in vitro and then in preclinical in vivo models. A lot of it is looking at pharmacodynamics, pharmacokinetics, the distribution of the drug in the organism, whether it is getting to its target, and preclinical safety. You also get an initial idea of dose.

Then comes the clinical part. Once you move into clinical trials, phase one trials focus on safety and establishing dose. Then there is a transition into phase two, where you look at finalizing the dose and ideally gaining some signal of efficacy. Safety information is collected throughout.

Then in phase three trials, you are really determining efficacy. These are often referred to as pivotal trials. Phase twos may be pivotal as well. Data from phase twos, if appropriately designed, and phase threes can be submitted for regulatory approval for marketing the drug.

Occasionally there are phase four trials, which typically happen post-approval and collect additional safety information or information on efficacy in the real-world setting.

Rohit: That is a great high-level intro, Greg. Thank you. Before we segue, and it is not too long in any podcast before AI comes up, we are going to talk about the use of AI and new technologies in the clinical trial process so it can be more efficient, cost effective, and faster. What are some of your thoughts on that?

And before that, if you could give some insights into how you got to this position and how you started your role. I understand you trained as a physician, so I would love to hear that story before we dive into the AI side.

Greg: I started off thinking I was going to be a basic science researcher working in a lab. In college, I was working in a lab during a summer research position, and someone said I should get an MD-PhD rather than a straight PhD because it would be easier to get research grants.

So I did an MD-PhD at UT Southwestern. My PhD was in neuroscience. I briefly thought about being a clinical neurologist, but in the mid-nineties the bread and butter of neurology was stroke and neurodegenerative disorders. In both cases, you made the diagnosis and then said good luck, go see occupational therapy because there was nothing disease-modifying.

So instead I went into diagnostic radiology. I returned to the Boston area, did my residency in diagnostic radiology, and then was a fellow at Mass General in neuroimaging. I was doing stroke imaging research and got involved in a clinical trial. I was helping run an NIH-sponsored clinical trial, and my mentor got me involved in a small industry-sponsored trial using a thrombolytic drug. They were looking at reopening of the artery on CT angiography to get an initial sense of efficacy.

I effectively became the core lab as a fellow for this trial.

A couple of years later, I was doing more stroke research at Jefferson in Philly and realized the lab was not really my jam. The chief medical officer from Icon came and gave a talk about things you can do as a physician-scientist in industry and mentioned that they had a radiology core lab. This was an ecosystem I had no idea about. You never hear about these things in medical training.

I went to Icon for five years and retrained as a cancer imager because that is where a lot of the endpoints are. Then in 2015, I came to Merck. I supported part of the cancer imaging portfolio, and then as organizational changes happened, I took on supporting clinical imaging across the entire portfolio, all therapeutic areas. Later we added clinical pathology as well, because assessing outcomes using pathology conceptually functions the same way. It is newer to have approvable endpoints based on pathology. Imaging processes had been worked out over a long time, so we were transposing those processes into that space.

Now going to the technology side of things, I like to say in radiology we were doing AI research before ChatGPT made it cool. AI is pattern recognition, and visual pattern recognition is something humans do all the time. You show a picture of a dog or a cat and you know immediately, even if you cannot describe explicit rules.

In radiology, models can see patterns that human eyes cannot, no matter how good a radiologist you are. There is a lot of interest in that. Shortly after I joined Merck, I started pulling together people from data science, statistics, clinicians, biomarker groups, regulatory, digital, and others across the organization to do research in this space.

Rohit: So given your deep experience in clinical trials and AI, especially now with new models like ChatGPT, what are some of the things you are seeing that are applicable in the clinical trials world?

Greg: So there are a couple of broad categories. Let’s start with one that is the easiest and most obvious business case for the use of AI in the clinical trials world. Then we can segue into things that are less obvious but, I think, scientifically and from a business strategy point of view, very interesting.

The easiest place to make the business case is that clinical trials are expensive and a lot of it is human resource cost. So there are many applications of AI for efficiency. In the preclinical space, AI is used for genome searches, target identification, drug design, assessing protein folding, and things of that nature.

Once you get into the clinical space, there is a lot of use of AI to support clinical operations. That includes creating documents, protocols, clinical study reports, informed consent forms, and reports of various kinds. There is also AI analysis. A huge amount of data gets collected, and manual review of all that data is extremely labor intensive. That is an area where AI can help.

One example of manual effort is the many kinds of reconciliation in clinical trials where data is gathered in one place and also in another place, and you have to make sure things match. That can be extremely labor intensive manually. That is where general AI use and specifically agents can help. You can say to an agent, retrieve data from this place, do the comparison, take an action based on the comparison, such as issuing a query to a site to ask for clarification. That kind of use is great for efficiency and is the most straightforward business case. That is being adopted across many industries, and in clinical trials where reports and reconciliation and analysis are important, it is a valuable tool.

Rohit: That’s amazing. I think that’s great to know. And then in drug development decisions, if we talk about AI applications in drug development decisions and automating tasks and making strategic decisions for the organization, what do you think about that aspect, Greg?

Greg: Efficiency is the obvious use case. The slightly less obvious but at least as impactful use case, and of course I’m speaking from my perspective as somebody who focuses on imaging assessments, is thinking about endpoints. Endpoints are measurements. Why do you make measurements? To make decisions. AI allows us to make better measurements for better decisions.

As an example, let’s use cancer. The traditional way of assessing whether a cancer drug is working is you do a scan before treatment starts. You find the tumors, pick a few to measure, add up their measurements, then do multiple scans during treatment. If they shrink, that’s a response. If they grow, that’s progression. At each assessment time point, you apply simple rules to classify as complete response, partial response, stable disease, or progressive disease. Then you extract an endpoint like objective response rate or progression free survival using rules like RECIST, a standard tool in clinical trials.

What we really care about is not tumors growing or shrinking. What we care about is patient survival. Objective response rate is a good predictor of survival at large N. When you have a large population, improvements in response rate indicate improvements in survival. The problem is that as N gets smaller, that correlation gets worse. There are many examples of drugs that looked good in early phase trials with dozens of subjects and then failed in phase three. That is a terrible outcome for patients and a huge waste of resources. A phase three trial can cost $150 million. Those pipeline decisions are made early in phase one B or early phase two.

Another application is picking the right dose of a drug. Traditional dose finding cranks up the dose until the patient has adverse events and then backs off. There are reasons why that may not be optimal. If you could compare survival in groups of 30 or 40 patients, you could get to a confident dose for late phase trials.

Here is where AI can come into its own. Scans contain information not visible to the naked eye. Models can see pixel patterns. When you look at a tumor, there is more information than size. Pixel patterns may correlate with necrosis, vascularity, or inflammation, reflecting aspects of the tumor microenvironment. If you have a training set where you can associate these patterns with a gold standard like biopsy, then you can do non-invasive assessment of the tumor microenvironment.

You could use that as a pharmacodynamic biomarker. For instance, drugs in immuno-oncology work better when tumors are inflamed. If you could measure that non-invasively across the entire patient, you could assess whether a combination partner is good. If all tumors light up with inflammation, that is a potentially good drug partner.

There is also the potential to look at early changes in tumors and directly predict survival rather than predicting shrinkage first. A downside of systems like RECIST is that they use fixed percentage changes and do not take into account kinetics. A common academic approach is to take total tumor burden and assume it consists of a treatment-sensitive fraction that decays and a treatment-resistant fraction that grows. If you fit a curve with a decay constant and a growth constant, the growth constant has been shown to be better associated with survival. That makes sense because tumors kill by growing.

The challenge is that systems like RECIST depend on picking a few tumors and measuring them. Anytime you sample, you assume the average drives the outcome, but that is not true. What kills the patient is the worst tumor, the most resistant and most aggressive. If you did not pick that tumor for measurement, you are blind to it. You want to measure everything.

You also want a full 3D outline of the entire tumor. Radiologist time is expensive, and drawing every tumor in 3D is not scalable. AI can do it. Tools do not yet automatically find every tumor, but once you point to a tumor, AI can draw it in 3D, propagate it across scans, make all the measurements, and feed that into modeling.
With a combination of direct AI assessments and assessments assisted by AI, you could get better measurements of efficacy and make better decisions about a drug pipeline, combinations, and dose selection.

Rohit: That’s a great explanation, thank you for that, Greg. So as you mentioned, a lot of this is exploratory and academic in nature. When do you see it moving into industry grade regulatory practices, because pharma, biotech, biopharma is a highly regulated industry segment? What are some of your thoughts around that space and any FDA insights you can provide?

Greg: What I would say is, first of all, with regard to the kinds of measurements I’ve talked about, you notice that I talked about using them in early phase decision making. This is purely internal decision making.

Now, as you move forward, pharma decision makers are conservative and risk averse. You have to do a lot of validation first. You validate internally, and the initial uses are internal uses. As evidence starts to accumulate, you can start building these more advanced assessments into phase two trials as exploratory endpoints.

In order for the FDA to accept a measurement of any kind, whether AI based or not, as an outcome in a trial, there needs to be strong evidence that those measurements are strongly associated with clinical benefit. Essentially, the process is that you start with internal decision making, then build it in as exploratory endpoints, then accumulate data and submit that to regulators as part of the overall package. As experience builds up, you can start thinking about using it to supplement regulatory decisions like supporting breakthrough designation or accelerated approval, and then someday potentially as primary endpoints.

The FDA put out guidance in January of this year on the use of AI in regulatory decision making. They laid out a framework for building what they call a credibility assessment framework. You have to define the context of use clearly, then assess the model risk. If you are making decisions about treatment or endpoints based on the output of an AI model, you have to consider whether it is the only factor in the decision or just a contributing factor, and what the potential risk is if it is wrong.

If you are making a treatment decision based on AI output, that is high risk. If the decision is not as directly about care, the risk is lower. You have to assess model risk and generate evidence commensurate with that level of risk. The evidence has to be generated in intelligent ways, avoiding pitfalls like data commingling or circularity. If you train a model on data and then test it on overlapping data, that can give inaccurate results that do not generalize. You have to think through all the pitfalls to build evidence the FDA can accept.

Right now, everybody is in exploratory mode and figuring out how to do this. The guidance from FDA in January was draft guidance. These draft guidances can remain in draft for years and reflect the latest thinking. There have been responses and published analyses, and pharma and bio have generated organized responses. That is where I would suggest people go to read about the FDA’s thinking.

The bottom line is whatever you are thinking of doing with AI in biopharma, if you want to bring it to regulators eventually, you need to engage early. Sit down and say, here is our plan, here is the technology, here is the data we trained it on, here is how we validated it, here is the context of use, here is the risk, and use that to build the credibility assessment framework.

Rohit: That’s amazing. And then Greg, you are AI in a very large biopharma organization. What are some of the challenges you run into in such environments and how do you overcome them? What are some strategies that you have followed successfully, if you would like to share?

Greg: Sure. So it’s a great question. One thing that big pharma has in massive amounts is data. If you are in a pharma that has run a large clinical development program, you are drowning in data. Some challenges are around data standardization. You will have legacy systems, and a big pharma may have dozens of legacy systems that collect data and cannot necessarily talk to each other. When you want a model to look at data, it helps to have a data standard.

That is something that helped radiology, which adopted AI early because radiology has the DICOM data standard. No matter the scanner manufacturer, they all generate DICOM data. That was possible because there were only a few major equipment manufacturers whose data engineers could agree on a standard. Other kinds of data are not standardized that way. That is an important challenge and a market opportunity for companies that want to create tools to interconvert, harmonize, and unify data. AI would be useful for this.

Another aspect is sensitivity around data access and patient consent in clinical trials. Clinical trial data is sensitive, and you have to put risk mitigation strategies in place to ensure you are not generating outputs that confuse or undermine what is known about a medication. You also have to think about whether subjects in a trial consented to that use of their data. The mitigation is working with people writing informed consent language to clarify that these additional uses are permissible.

Finally, aside from data, there is the people side. Data scientists and AI engineers are brilliant, but they may not understand the problems that need to be solved. They may come up with solutions in search of problems or solutions that are difficult to apply. Any organization building an AI team needs to bring together people who understand the challenges, like clinical developers and strategists, with people who understand the tools, like data scientists and statisticians. Statisticians are critical because of pitfalls like overlapping data and overtraining. What you want in an AI team is a multidimensional view of the problems and tools, and collaboration to solve the problems.

Rohit: That’s a great insight. So as we come to the end of the podcast, Greg, what are your thoughts for the future? When you look into the crystal glass, what small, medium, or big changes do you see coming our way?

Greg: People are enthusiastic that it will do everything, walk your dog, run your clinical trial, and butter your bread. AI is a set of tools, potentially very powerful, but you have to use it with caution because how you train and validate it matters.

In the future, what I envision is the early phase of drug development getting faster as AI is applied to molecule design, preclinical aspects, and extracting more information in clinical development from each subject. In later phases, AI will make trials more efficient in workload, resourcing, and insights around recruitment, like where to find the right patients.

So I see an acceleration of drug development through each stage that AI can enable as long as it is done with appropriate ethical safeguards and scientific rigor.

Rohit: Absolutely. And it will bring drugs to market faster if we are able to envision that. Thank you, Greg. I really appreciate it. These were very insightful thoughts you provided in this podcast. Anything you would like to say in closing?

Greg: Thank you very much for inviting me, and I look forward to seeing some other guests on your show now that I am aware of it.

Rohit: Thank you, Greg. Really appreciate it.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Top 10 AI Trends Shaping Healthcare in 2025: Insights from Season 6 of The Big Unlock

Season 6 of The Big Unlock podcast captures a defining moment for healthcare. Across conversations with CIOs, CMIOs, CMOs, CAIOs, digital transformation leaders, and innovators, one message comes through clearly: artificial intelligence has moved beyond experimentation. In 2025, AI is no longer something healthcare organizations are “exploring,” it is becoming embedded into how care is delivered, how work gets done, and how health systems think about scale, sustainability, and growth.

Season 6 reveals a deeper transformation, leaders are rethinking workflows, workforce models, patient access, governance, and the economics of care, with AI acting as an accelerator rather than a silver bullet. 

Here are the Top 10 trends discussed throughout the 2025 season, a reflection of what healthcare leaders are prioritizing today and where the industry is headed next.

 

AI Is Becoming Operational: Moving Beyond Pilots to Real Outcomes

One of the strongest signals from Season 6 is that AI has crossed the pilot phase. Health systems are no longer satisfied with proofs of concept; they are demanding measurable, operational impact.

Guests across the season described how AI is now embedded into day-to-day workflows, from clinical documentation and scheduling to capacity management and care coordination. These deployments are delivering tangible results: reduced clinician burnout, improved access, faster turnaround times, and more efficient use of limited resources.

What differentiates successful organizations is not the sophistication of the technology, but the discipline of implementation. Leaders emphasized that operational AI requires governance, workflow redesign, and ongoing measurement – not one-off experiments.

The message is clear: 2025 is the year AI became real for providers.

 

The Rise of Ambient Clinical Technology

Ambient clinical listening emerged as one of the most discussed and widely adopted technologies in Season 6. Rather than being framed as a documentation shortcut, ambient technology was described as a fundamental shift in how clinicians experience care delivery.

By capturing conversations in real time and generating structured clinical notes, ambient tools reduce after-hours documentation and allow clinicians to remain fully present with patients. The result is not only time savings, but also better clinician-patient relationships and improved note quality.

At the same time, guests were clear that success depends on thoughtful rollout. Training, trust, and change management are critical. When implemented responsibly, ambient technology is quickly becoming foundational to modern clinical practice.

 

The Shift to Agentic AI and AI-Native Healthcare Design

Season 6 marks a noticeable shift from generative AI that supports tasks to agentic AI that can take action. Leaders discussed AI agents that can handle referrals, manage prior authorization workflows, coordinate care tasks, and support operational decision-making.

This evolution signals a broader transformation toward AI-native healthcare design. Instead of layering AI on top of existing processes, organizations are beginning to redesign workflows around intelligent systems that operate within defined guardrails and escalate to humans when needed.

While still early, these discussions make it clear that agentic AI will play a critical role in scaling care delivery without proportionally increasing workforce size.

 

Workforce Augmentation: AI as a Partner, not a Replacement

Across Season 6, leaders were remarkably aligned on one point: AI is not about replacing clinicians, it is about enabling them.

Guests described how AI is taking on repetitive, administrative, and low-value tasks, allowing clinicians to focus on complex decision-making, patient relationships, and care quality. This shift is particularly important in an environment marked by workforce shortages and burnout.

However, adoption depends on trust. Clinicians need to understand how AI works, where its limits are, and how decisions are made. Season 6 reinforces that the future workforce will be defined by effective collaboration between humans and intelligent systems.

A recurring message: AI should free clinicians to practice at the top of their license.

 

Data Infrastructure & Interoperability Are Now Strategic Priorities

Another recurring theme is the realization that AI success is fundamentally a data problem. Without clean, connected, and interoperable data, even the most advanced models fail to deliver value.

Guests emphasized investments in cloud platforms, standardized data pipelines, and interoperability frameworks. Pediatric networks, population health initiatives, and enterprise AI strategies all pointed to the same conclusion: data infrastructure is no longer a back-office concern, it is core to clinical and operational strategy.

In 2025, data readiness is increasingly viewed as a prerequisite for innovation rather than a downstream technical task.

Data modernization is no longer an IT project, it is enterprise strategy.

 

The Importance of Responsible AI, Governance & Safety

As AI adoption accelerates, Season 6 makes it clear that governance has become a top priority. Leaders spoke openly about the risks of deploying AI without appropriate oversight, particularly in clinical and administrative decision-making.

Many organizations have established formal AI governance structures that include clinicians, technologists, compliance teams, and executive leadership. These groups are responsible for evaluating use cases, monitoring bias, ensuring safety, and setting boundaries for automation.

Rather than slowing progress, responsible AI practices are helping organizations scale with confidence and build trust among clinicians and patients alike.

The theme: Responsible innovation is not optional, it’s foundational to trust.

 

Digital Care Navigation Is Becoming the New Front Door

Several episodes highlighted a shift in how patients access and experience care. Digital care navigation platforms are increasingly serving as the “front door” to healthcare, guiding patients to the right care setting at the right time.

AI-powered navigation tools help reduce friction, improve access, and optimize system capacity. For health systems, they also play a critical role in managing demand, improving patient satisfaction, and supporting growth strategies.

Season 6 positions digital navigation not as a consumer add-on, but as essential infrastructure for modern healthcare delivery.

 

AI in Revenue Cycle and Administrative Simplification

While clinical use cases often dominate AI conversations, Season 6 repeatedly underscored the massive opportunity in administrative and revenue-cycle workflows.

Leaders discussed how AI can streamline prior authorizations, reduce denials, improve documentation accuracy, and automate routine administrative tasks. Given the scale of administrative costs in healthcare, even modest efficiency gains can have outsized financial impact.

These discussions reinforce that some of AI’s most immediate and sustainable value lies in simplifying the non-clinical work that burdens care teams and organizations.

This is one of the most financially meaningful areas for AI in 2025.

 

Co-Innovation Models Between Health Systems and Technology Partners

Another important trend is the rise of co-innovation models. Rather than buying off-the-shelf solutions, health systems are increasingly partnering with technology companies to build solutions together.

This approach allows tools to be shaped by real-world clinical workflows and operational constraints. It also accelerates adoption, as clinicians and leaders have a stake in the solution from the outset.

Season 6 shows that co-innovation is becoming a preferred path for developing scalable, relevant, and trusted digital solutions.

 

The “Healthcare Trilemma”: Rising Demand, Workforce Shortages & Margin Pressure

The final trend ties many of the season’s themes together. In the episode focused on solving healthcare’s trilemma, leaders articulated a structural challenge facing nearly every health system: rising patient demand, persistent workforce shortages, and increasing financial pressure.

The conversation emphasized that traditional growth models. hiring more staff or adding more facilities, are no longer sufficient. Instead, organizations must focus on disciplined prioritization, co-innovation, and AI-enabled orchestration of care.

This trend reinforces a central message of Season 6: AI is not just a tool for efficiency. It is becoming essential to healthcare’s long-term resilience and sustainability.

 

Looking Ahead: Setting the Stage for Healthcare’s AI-Driven Future in 2026 

The conversations in Season 6 of The Big Unlock paint a clear picture of healthcare in 2025. AI is no longer peripheral. It is reshaping how care is delivered, how clinicians work, how patients access services, and how health systems remain viable in an increasingly complex environment.

The real “big unlock” is not adopting AI for its own sake, but using it to redesign healthcare around people, data, and intelligent systems – responsibly, thoughtfully, and at scale.

The “big unlock” for 2025 is not simply adopting AI tools.
It is redesigning healthcare around AI, moving from incremental change to structural transformation. Health systems that embrace these themes will shape the next decade of healthcare delivery.

Rural Health Transformation and the Future of Patient-First Care

Season 6: Episode #191

Podcast with Lisa Hunter,
Senior Director of Federal Policy
& Advocacy, United States of Care

Rural Health Transformation and the Future of Patient-First Care

To receive regular updates 

In this episode, Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, discusses how her organization is working to ensure every American has access to affordable, high-quality care, with a particular focus on rural communities. She explains the new Rural Health Transformation Program—a 50-billion-dollar, five-year federal investment that gives states a rare opportunity to redesign rural health delivery, address workforce gaps, and move toward “patient first care” models that emphasize coordination, whole-person care, and sustainable payment structures.​​

Lisa highlights a growing trust gap around AI in healthcare, noting that patients are more comfortable with AI in back-office and ambient use cases compared to roles that feel like they replace clinicians. She stresses the need for rigorous listening, research, and language that resonates with people, so policy and technology decisions reflect real experiences rather than abstract concepts. Take a listen.

Video Podcast and Extracts

About Our Guest

In her role as Senior Director of Federal Policy & Advocacy at USofCare, Lisa leads a team of policy experts and strategists to advance the organization’s health advocacy agenda with Congress and the administration. Her work largely focuses on affordability, access, and translating what people want and need from the health care system into policy solutions for federal uptake. Lisa brings to the USofCare almost twenty years of experience working to expand access to affordable health care through roles in the federal government, nonprofits, electoral campaigns, and the private sector.

Most recently, Lisa led strategic partnerships at Families USA, and oversaw advocacy and government affairs at the Better Medicare Alliance. Prior to joining the advocacy community, Lisa spent several years as a consultant with Avalere Health helping clients operationalize regulations with respect to the Affordable Care Act and Medicare Advantage. Early in her career she served as a political appointee at the U.S. Department of Health and Human Services during the Obama Administration, as a Congressional staffer, and as a Peace Corps volunteer teaching literacy at a primary school in Guyana. Lisa’s expertise on health policy implications for everyday people appear in media outlets such as the New York Times, Axios, Politico, Inside Health Policy, The Hill, Fierce Healthcare, and others.


Q: Hi, Dr. Michael Docktor, welcome to our Big Unlock podcast. We are really happy to have you as a guest on our show. Uh, it’s on our sixth season now, and, uh, we are looking forward to this conversation. I’m sure we’ll have a very engaging and interesting conversation about dog health, about healthcare in general, and the new trends about AI and all the buzzwords that people want to hear. Welcome to our show — we’d like to start with introductions. Happy to have you give your introduction. Thank you.

Michael: Yeah, thank you so much for having me. Yeah, I’m Michael Docktor, co-founder and CEO of Dock Health. I’m an ologist by trade. I am now on this, uh, healthcare venture outside of Boston Children’s Hospital where I started my GI career.

I was a busy clinician working on the clinical side as well as in innovation and informatics, and found that we had wonderful tools in the world outside of healthcare and struggled with my own challenges around managing all the tasks that are part of patient care. I found that I was using task management and project management tools that were not built for healthcare.

I scratched my head and wondered why we don’t have these things for healthcare. That was a journey. We started just over five years ago. We spun out Dock Health from Boston Children’s, and we’ve been on a very exciting journey in the world outside the academic walls since then.

It’s been fun. I’m excited to talk to you more about, uh, what we’re doing.

Q Great. That’s a great introduction. Thank you for letting our listeners know. We usually like to start with how you came into healthcare because everyone has an interesting story about what inspired them to become a physician.

For you, it’s particularly interesting because you’ve created this interface between design, technology, and healthcare — and you went beyond just visualizing what you wanted to do or asking why somebody doesn’t fix it, to actually building it yourself. I’d love to hear more about how you came into medicine and then into technology.

Michael: I could probably spend the entire podcast on this question. Obviously, my last name is Doctor, so there was some planting occurring there, and there’s something to be said for that.

One of my earliest memories was wanting to grow up to be a doctor. My younger sister had some GI issues when we were young, and I became very close with her gastroenterologist. I followed her on her journey and, unbeknownst to me, ended up following one of my mentors and was inspired to do the work for other children the way my sister was cared for. That was the initial inspiration.

You mentioned design. That’s interesting because my mother is an interior designer, my father is a dentist who specialized in aesthetics, and design — how things look, feel, and work — has always been part of my DNA. It was an amazing journey to go from being a traditional doctor in pediatric gastroenterology to discovering the importance of user experience and user interface.

Then the iPhone came out, then the iPad, and that really started me on my journey of exploring app development and software, and wondering why we didn’t use these wonderful devices in our pockets the way we should. That journey started more than 10 years ago and has led me to this perfect intersection of healthcare, design, and informatics, creating better experiences for patients and providers.

There’s a lot to unpack there, but people ask me if I would do it differently if I had the chance to do it all over — and absolutely not. I’m doing exactly what I want to be doing right now.

Q: Thank you for sharing that. That gives us so much perspective into how you came into this field, the influence of your parents, and how everyone around you inspired you to do this. That’s really interesting.

That leads us into how you built Dock Health. Tell us some examples of how you saw this becoming transformational in actual implementations with clients. When you built the tool, did you visualize exactly what it would do? Did it go beyond what you thought it would achieve in a healthcare setting? We’d love to hear more about that.

Michael: We’re far beyond where I ever thought we’d be when we first started this journey. That’s the exciting part. Fundamentally, we have such an administrative and operational challenge in healthcare. I saw it firsthand as a busy clinician struggling to manage all the clinically adjacent work that had to be done for my patients.

For example, I might have a patient with Crohn’s disease who needs to go to an infusion center. There are all these downstream tasks and administrative steps that need to be done by a team of people. We didn’t have assistants to do that, and the electronic health record wasn’t built for it.

A quarter of the $5 trillion spent in healthcare goes to administrative and operational challenges, and there really are no tools built for that. We rely on paper checklists, email, faxes, and spreadsheets to manage all the work happening outside the electronic health record.

For me, the realization was that I was using wonderful project management and task management tools to run software projects in my innovation and informatics roles—and yet nothing like that existed in healthcare. Patients, in many ways, are projects. There are tasks that form the essence of care, and they need to be tackled, managed, and collaborated on, with visibility and accountability across teams. That didn’t exist.

What we are now doing is serving as that productivity platform for healthcare, one that sits alongside the electronic health record in synergy, helping manage all the administrative and operational tasks of patient care in ways the EHR wasn’t designed for.

Some examples would be managing patient intake and all the processes associated with it. Referrals, inbound and outbound, with all the paperwork, eligibility checks, and faxes—those workflows are still incredibly manual. Referrals are a great example: 80% of referrals that come into major academic medical centers are still arriving by fax, despite the fact that they’re using Epic, a wonderful electronic health record.

These processes are still incredibly laborious, take too long, and are inefficient. Patient care suffers along the way. There’s a gigantic bottleneck around the administrative and operational work that moves patients through their journeys, and that’s what we’re focused on fixing.

Q: This is what we hear from a lot of our clients and other CIOs and C-suite leaders who come to our podcast—that this is one major problem with healthcare. It’s siloed, and the processes are really stuck in the dark ages.

We were talking to somebody from Athena, and they said they had an 800-person offshore center in India just to screen faxes. When a fax came in, one person looked at it to see if it was a pizza order or a referral. It sounds unbelievable in this day and age, but that’s how it works. I’m amazed to hear this from you as well. It’s remarkable.

Michael: Yeah. In fact, Athena is a partner of ours, and we’re working on referral management. It’s an incredibly antiquated process where everyone loses visibility. The amount of manual labor required to process these things is shocking in this day and age, when they can be handled through process automation, AI, and agents.

Q: Exactly. You’re talking about agentic, we’re talking about voice agents, and yet we’re still dealing with faxes. That’s really interesting to know.

Michael: There is reason to be hopeful. Healthcare is always many decades behind, but the adoption of AI is progressing more rapidly than I’ve seen any technology adopted in healthcare. There’s reason for hope.

Q: That leads into my next question, but before we get there, you mentioned Dock Health as a productivity platform. That’s what it does for doctors, clinicians, and patients. But when we talk to our doctors, clients, and health systems, the one word that always comes up is complexity. They deal with so many different systems and have to learn something new each time.

Where does Dock Health fit in? Is it another system they have to manage, or does it help reduce that burden?

Michael: Yeah, it’s all about reducing the burden and improving the user experience. That’s been fundamental to our belief system since the founding of the company.

First and foremost, we’re trying to become the productivity platform and the hub that handles the administrative and operational work. Instead of being “another system,” we’re often replacing spreadsheets, paper checklists, emails, and faxes—the ways we’ve traditionally managed the 50% or more of administrative and operational tasks required for patient care.

The EHR is great for clinical work, billing, prescribing, and scheduling, but so much happens downstream that isn’t covered. I’d argue we are creating the hub for that. Just as the EHR is the clinical hub, Dock Health serves as the operational hub. Together, it’s really one plus one equals three.

We’re also aiming to be much more consumer-like in our approach. Our tool can onboard a customer in 30 minutes. We offer a free trial, and for small organizations that want to get up and running, they can start using it right away—just like downloading an app. It’s lightweight, highly configurable for end users, and designed with a strong focus on user experience.

The real challenge is that clinicians don’t want another tool. They’re busy and need to spend their time in the EHR. Our core users are often the super users: front office staff, back office teams, operational leaders, and administrative staff who leverage our tool every day.

The important piece is that we connect to the electronic health record and provide visibility for clinicians. If they’re interested, they can see where a patient is in their journey or where a process stands, but they don’t have to be in our system all day, checking tasks or learning another workflow.

The intent is to provide that operational hub for administrative and support staff—the essential members of the care team—while clinicians continue their work in the EHR and often drive tasks into our system through their orders and actions there.

Q: Is the integration with the EHRs native, like with Epic, Cerner, and the big ones?

Michael: Yeah. We’re on the marketplace with a number of the top EHRs, including Epic and Cerner. We’re also working with Mayo Clinic, their Mayo Clinic Platform, and their Deploy platform.

The other thing I’d mention is that many organizations use our tools without being integrated with the electronic health record. That’s often because they’re smaller practices—mental health, concierge care, or primary care—that simply need a hub to handle administrative and operational work and collaborate as a team.

We spend a lot of time helping organizations define their processes, and those processes can then live in Dock, where they can be collaborated on and turned into operational best practices. That’s something that often doesn’t happen in traditional healthcare organizations, and our tool is valuable even when it’s not connected to an EHR.

Of course, the real value comes when we integrate with systems—EHRs, CRMs, patient engagement tools—and serve as the hub while automating as many tasks as possible. That’s when the flywheel starts turning, and organizations begin to feel the benefits of automation and work reduction. It ultimately moves the needle in a measurable way.

Q: So, you’re saying if there’s an integration with the EHR, then it’s end-to-end and people can see a complete view of what’s happening. But even without the EHR, because it helps with workflow management, it’s valuable for practices?

Michael: It’s just like every other industry. They have Asana, JIRA, Trello—all these tools where a lot of the real work gets done. That provides value in itself by giving a clear view into where the patient is in their journey and what process they’re following.

When we integrate with an EHR or other systems, we can then automate those workflows. For example, when a fax comes in, we can launch a workflow for a new patient referral. When a lab order is placed, we can launch a workflow for follow-up. Or when a patient has a procedure, we can launch a process for their downstream follow-up.

Q: That leads into the next question, which is your learning journey with AI. What advice do you have for our listeners about where AI is headed? And with voice agents and agentic tech being buzzwords, where do you see Dock Health going? Are you also looking at implementing voice agents?

Michael: AI is incredibly exciting. I’ve put it out there that we’re an AI-first company. We’ve been thinking about this for a while, and we already have what we call Dock Intelligence in production with customers. We started with the basics, using foundational models and generative AI to process large troves of data.

Now, we can summarize all the work being done for a patient and create a snapshot for the end user—showing all tasks, workflows, patient context, and even clinical context if available. That gives a quick overview of what’s happening. Users can edit that snapshot if needed, or generate a note that writes back to the EHR to keep the operational and clinical record in sync.

That’s the first step in our AI journey. From there, we realized tasks bundle into workflows, workflows can be automated, and now we’re starting to farm out those tasks to agents and AI. For example, a voice agent could follow up with a patient to confirm a referral or review lab results. We’re actively pursuing that, as well as leveraging AI to extract data from faxes to automate referral processes.

AI is the big unlock. In the next three to five years, I believe most administrative and operational tasks will be handled by automation and AI agents orchestrating together. These agents need rails to run on and structure to guide them, and end users must remain in the loop to provide oversight and visibility. But the lion’s share of this work will be handled by agents—and we’re building that future right now.

Q: Are you aligning specifically with any particular LLM or provider, or are you going to be completely agnostic?

Michael: I’d like to think we’ll be agnostic. We’re doing plenty of building on some of the foundational models ourselves, and we’re partnering where we can with great tools. For example, with voice agents, we’re not necessarily building them ourselves—there are excellent options out there. What we are doing is building our own homegrown AI agents that can manage processes and facilitate handoffs from task to task.

Our approach has always been to recognize that there’s a wonderful ecosystem out there. We want to be the hub that connects to the best-of-breed systems—whether that’s Epic as an EHR, Salesforce as a CRM, or other tools we can leverage to create a healthy ecosystem. That’s what we’re pursuing.

Q: I wanted to ask a question about that because with the LLMs, one of the main problems is the hallucinations or the repeatability or the trust factor there. So I saw that Dock is HITRUST certified. So, I just wanted to ask, what are your views on that? Because in terms of using generative AI when we talk to our clients, uh, for implementations on LLMs, or they’re more comfortable certainly with the administrative tasks, but even with the administrative tasks there’s always the question of what are the guardrails you put around that and how do you make sure that the results that you are seeing or you are displaying on Doc Health, you know, stay within that, those bounds of accuracy. Whathat are your thoughts around that?

Michael: AI is incredibly exciting—it’s moving at the speed of light, and everyone wants to benefit from it. I do think administrative and operational areas of healthcare are lower-hanging fruit and far less risky. We’re not yet in a place where we can reliably use AI for absolute clinical decision support and autonomy, though I believe we’ll get there in the not-too-distant future.

For now, the clunky and manual administrative work is ripe for AI. Still, we need to be mindful of potential hallucinations. In our experience so far, we haven’t seen issues, but we’ve put safeguards in place. That means keeping a human in the loop to ensure outputs are appropriate and relevant. We also give users the ability to edit results before they’re sent—whether it’s a summary being emailed to a colleague or written back into the EHR as a clinical note.

It’s essential to show your work. If we’re pulling data from various sources, we show those sources. We keep users in the loop, give them control to review and edit, and maintain tight feedback loops to catch and address anything off.

So far, even foundational LLMs have been surprisingly strong in our relatively narrow use cases. The real challenges will come as we move toward higher-risk clinical decision support—but I’m confident we’ll get there quickly.

Q: It’s interesting you mentioned humans in the loop and the fact that people can review or edit what’s being generated. But with agents, one of the key defining characteristics is autonomy—they can make API calls, send emails, even browse the web to find and act on information. How do you think about that level of control being handed over?

Michael: I think it’s all about balance. The value of task automation and workflow automation is clear. For us, one of our strengths is providing a user interface where the end user can actually see where a process is in its journey.

We’re working on features like showing confidence levels or confidence intervals for data extracted—for example, from a fax. That way, we not only show our work but also give transparency into how accurate that extraction might be. Using our interface, which breaks workflows into tasks, we can show exactly where a process stands. If we believe human involvement is needed, we assign a task and call someone in to review.

Even in the agentic future—which is already upon us and actively being built and tested—we see ways to keep humans in the loop. Operating entirely in a vacuum is risky. Part of my mantra, coming from clinical practice, is that I lacked visibility and accountability in the work being done on behalf of my patients, lost in a black hole of faxes and emails. It’s important to show where the patient is in their journey, where the process stands, whether an agent is handling it or automation is moving data between systems. Giving people visibility and the ability to drill down is critical.

Q: That’s an interesting viewpoint. You mentioned the front and back office and clinicians, but I didn’t realize patients might also have visibility into the system.

Michael: That’s certainly the vision for the future. Right now, our solution focuses on creating visibility and accountability for the care team—clinical and operational staff. But ultimately, the patient is part of the care team too. I would love to see a future where patients are assigned tasks and the rest of the care team has visibility into their progress. I think that’s inevitable. For now, we’re focused on giving the traditional care team the tools they need, but over time, I see patients and their home-based care team being part of that ecosystem.

Q: So I think we are almost at the end of the podcast. We would like to conclude by asking you what you think, maybe give a horizon of like a year and then maybe a five-year horizon. What do you think the top trends that are going to be in AI, and particularly for you at Dock Health? What are the three things that you are really keeping close tabs on and you feel that it’s going to really impact your product and be very transformational.

Michael: It’s tough to predict because AI is moving so fast. Moore’s Law doesn’t apply anymore—the doubling is happening every few months. Everything right now is AI, and “agentic” is the word of the day. I’ve even heard “ambient agents.” We see our role as orchestrating workflows where agents will carry out the majority of tasks.

When we started Dock Health, I imagined a day when it would be smart enough to handle processes automatically. AI has accelerated that roadmap by five to ten years, and the pace keeps shrinking. I truly believe that in the next five years, when healthcare spending in the U.S. reaches $10 trillion, the $2.2 trillion spent on administrative and operational costs may actually shrink because of operational efficiencies unlocked by AI.

We want to give care teams superpowers. Administrative and operational staff deserve better tools to do their work. Just as ambient scribes are now relieving clinicians from documentation, I believe AI will do the same for the administrative and operational burdens in healthcare. Within three to five years, I expect most of that work will be automated. Humans will still play a role, but much of it will feel like it just happens—almost magically.

If you zoom out five years from now, it will look like magic. But by then it will feel obvious. And that excites me, because at the end of the day, patients, our economy, and the world need more efficient care. The fact that we waste a trillion dollars a year on administrative tasks is shameful. Patients are asked to take on too much, like reminding us about referrals or tracking down lab results. These things happen because we’re human and don’t scale well. But now we have incredible tools at our fingertips, and I believe the next few years will be the most exciting time healthcare has ever experienced.

If we zoom out five years from now, it’s going to look like magic—but by then it will feel obvious. I’m excited for that future because, at the end of the day, patients, our economy, and our world need more efficient care. The fact that we waste a trillion dollars a year on administrative and operational tasks is shameful.

Too much of the burden falls on patients. Physicians and care teams often say, “Call me if you don’t get your referral in a couple of days,” or, as I saw with my own mom recently, patients are left chasing down lab results. These things happen because we’re human and we don’t scale well.

Now, we have incredible tools at our fingertips. That’s why I believe the coming years will be the most exciting time in healthcare that I’ve ever experienced—and likely the most exciting time the world has ever seen. Healthcare is primed for transformation and opportunity.

Q: Thank you for being with us on our podcast. It was a wonderful conversation, and we look forward to sharing your vision for the future with our listeners.

Michael: Thanks so much.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Why the Real Future of Digital Health Is Human-Centered – Not Just AI-First

Why the Real Future of Digital Health Is Human-Centered - Not Just AI-First

Despite significant technological advances in artificial intelligence, the future of digital health is increasingly focused on a human-centered approach that prioritizes personalization, empathy, and holistic care over pure automation. Most experts agree that the future points toward a blend of AI-driven insights and human expertise. AI excels at processing vast amounts of data to predict risks and suggest optimal treatments, while human healthcare professionals provide the essential elements of empathy, complex decision-making, and emotional support that technology cannot replicate. 

This idea of “digital hybridization” was discussed on two recent episodes of The Big Unlock podcast, one featuring Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare and the other Dr. Felicia Newhouse, Founder, AI-Powered Women. They both shared their insights on the evolution of AI and how virtual care is reshaping access and improving outcomes while at the same time enhancing patient engagement and allowing a more human-centered experience.

 

Towards a Human-Centered AI Model for Digital Well-Being

Ever since the earliest days of its inception there was this fear of AI replacing humans, or at least severely reducing much needed human interactions. As Felicia put it, “we all feel the need to belong.” These elements of human touch that we all crave are never going to go away, and they are critical as AI is becoming increasingly ubiquitous in all industries, but it is profoundly important in healthcare.

As a cardiologist, for Dr. Gallagher, the melding of technology and the human side of medicine was always there. “I always saw cardiology as field that combines technology and medicine together. It’s procedural based, and by nature it has always been cutting edge. You work in a lab that looked like something from the Starship Enterprise, screens everywhere and all sorts of incredible technology.”

He went on to explain that he also spent a good part of his career in rural health and that provided a stark contrast to that high-tech environment. Yet, he realized how he could use technology to bridge those worlds and bring quality care to those underserved communities, first with telehealth and now AI.  He told show host Ritu Uberoy that he has now dedicated his career to this “virtual care space” managing underserved, untreated populations.

 

A Vision for Virtual Care

AI adoption in healthcare has always involved a lot of changing of hearts and minds, both on the provider and the patient side. To achieve his ultimate vision of virtual care, Chris says, “simplicity is key.” 

“The key to our vision of virtual care, to getting more people to use it, was making it as user friendly as possible, not only on the medical practitioner’s side but also on the patient side. It had to be simplistic and never fail. In our inception days we used this analogy, the system had to be Fisher Price easy –you push a button, the cow goes, moo,’ everyone’s smiling and laughing. That was our ultimate goal to get it that push button easy.

Today, having provided that, Chris says he sees immense opportunity and possibilities. “Opportunities within our back office functions to simplify and streamline the business of medicine. We also see opportunities to improve the provider’s experience and minimize burnout. We have nearly 800 users for whom we have improved and simplified their experience when it comes to patient care.”

Then he told Ritu that he also sees opportunities to enhance patient care itself using new technology that helps connect them more to their doctors and nurses and not distance them from them as was once feared.

 

Can We Train Machines to Be More Empathetic?

Empathy and compassion need to be a cornerstone of human-centered healthcare. Can virtual health agents be taught to be empathetic? While current AI agents, and future “healthcare robots” may not experience empathy in the same way humans do, the ability to display empathetic behaviors can foster more positive and meaningful interactions between humans and machines.

Felica said that machines can process complexity, but only humans can really feel the complexities of true empathy. However, despite that distinction she says we can shape and mold and redefine the meaning of “artificial intelligence” to a kind of “sympathetic intelligence” as we continue to evolve human-centered AI design in the years to come.

 

Feminine Leadership Principals

Clinical studies have consistently shown that females are naturally more empathetic than males. So maybe what AI in healthcare needs is not so much a human touch, but a woman’s touch. Felicia certainly thinks so. “When we say feminine leadership principles, it doesn’t mean you have to be a woman. It just means that they’re grounded in kind of more feminine way of showing up as a leader, which is intuition and empathy and things like that.”

 

How Automation Can Unleash Human Potential

At the end of the day, rather than diminishing humans, AI can help us reach our full potential. As Felica put it, once we can fully use AI automate the mundane things that are holding us back, who knows what can be accomplished? Therin lies its true power she believes.

“We can leverage these technologies to essentially automate and offload the aspects of yourself that are holding you back so you can become a much more human centered and whole leader and whole human that has more to offer to the world around you. We can partner with AI in that capacity because if you think of AI as kind of an emerging species that we’re parenting. Right now, it’s in the toddler stage, and it’s up to us to raise it right. AI has its own brilliance to offer, and we have our own brilliance to offer. We have to look at our future as kind of a hybrid species that’s collaborating together.”

Solving Healthcare’s Trilemma with Focus, Co-Innovation, and AI

Season 6: Episode #190

Podcast with Matthew Blosl,
Chief Executive Officer, DexCare

Solving Healthcare’s Trilemma with Focus, Co-Innovation, and AI

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In this episode, Matthew Blosl, CEO of DexCare, discusses how he helps high-growth healthcare technology companies navigate critical inflection points by pairing disciplined focus with a culture that embraces failure as a path to innovation. He describes DexCare’s journey from a Providence Health incubated initiative to a scaled care orchestration platform that helps health systems address a “trilemma” of rising patient demand, clinician shortages, and margin pressure.

Matt explains DexCare’s co-innovation model, where every health system becomes an innovation partner rather than a one-size-fits-all implementation, enabled by modern data and AI capabilities. He outlines a pragmatic AI roadmap: first improving internal operations, then enhancing existing products, and finally accelerating true product innovation, while warning that AI can easily drive teams off-mission without strong focus. Matt also points out how fast things are shifting in healthcare and encourages leaders to rethink how they run their organizations and come together more often to tackle the challenges ahead. Take a listen.

Video Podcast and Extracts

About Our Guest

Matthew Blosl is Chief Executive Officer and a board member of DexCare, the leading digital platform for orchestrating patient demand and care access. With over 20 years of executive leadership experience in technology-driven organizations, Blosl is recognized for building high-performing teams, scaling commercial operations, and driving strategic growth that delivers measurable customer and enterprise value.

Prior to joining DexCare, Blosl held a senior leadership role at Experity, where he led commercial initiatives that significantly expanded the company’s market presence and helped secure its leadership position in the urgent care space. Throughout his career, he has fostered cultures of operational excellence and innovation, consistently delivering results in high-growth environments.

Blosl holds a degree in engineering from the University of Michigan and completed his business education at Stanford Graduate School of Business. He brings a powerful combination of technical rigor and strategic acumen to his leadership, grounded in a passion for transforming healthcare access and outcomes.

At DexCare, Blosl is leading the company into its next phase of growth, focused on expanding platform innovation—including the introduction of AI-driven capabilities—and deepening adoption across leading U.S. health systems. Under his leadership, DexCare continues to transform how patients find and access the right care, at the right time, with the right provider.


Ritu: Hi everyone. Welcome to our next episode of The Big Unlock podcast. We are in Season Six now with 180+ episodes, and today we are welcoming Matt Blosl to our podcast. He is the CEO at DexCare. Welcome once again to all our listeners. My name is Ritu M. Uberoy. I am the co-host here at The Big Unlock podcast and Managing Partner at BigRio and Damo Consulting. Welcome to the podcast.

Rohit: Super excited to be here with Ritu and with Matt. I’m Rohit Mahajan, CEO and Managing Partner at BigRio and Damo Consulting, and the co-host of this podcast. Over to you, Matt.

Matt: Great, thank you. Yes, I’m Matt Blosl, CEO of DexCare. I’m very familiar with not only this space in healthcare but also with high-growth companies. DexCare is my seventh venture private-equity-backed company, and I’m excited to talk about everything we have going on here at DexCare.

Ritu: Great. So we’ll jump right in. Matt, our listeners always love an origin story, so we would like to hear how you got to where you are today. And also, very interestingly, like you mentioned, this is your seventh gig. But something different here is that, as you said in our intro call, DexCare had already gone through a very steep growth curve when you came in. Usually, it’s the other way around, where you’re helping the company grow into that phase. So how has it been different for you this time, and what lessons have you learned or what do you think the difference has been?

Matt: Yeah, it’s interesting. When I reflect on my career, I’ve typically not been the founder of businesses. I’ve come in usually at some inflection point. DexCare is a unique story in that it was incubated within Providence Health, then spun out, and then had three to four years of hyper growth. The company got to a point that many high-growth companies do, where they reach an inflection point. What it takes to get from an idea on a napkin to a certain point requires one kind of skill set, and then taking it from point B to point C often requires a different viewpoint.

So for me, coming into DexCare was a very familiar point—well-established business, great clients, a lot of growth—but taking the next step in maturing the business requires looking at things differently. That’s what I’ve done at DexCare and throughout the last 15–20 years: coming into a well-established business and figuring out how to get it to the next level.

Rohit: So Matt, this is super interesting. Could you share your interest in healthcare—what got you started—and talk a little about your story and journey to where you are today?

Matt: Yeah, it’s interesting. I don’t know that it’s the typical story. I spent most of my career not in healthcare. My wife is a physician, so I always said I didn’t need to go into healthcare. Then about 12 years ago, a private equity firm tapped me on the shoulder and asked me to help scale a healthcare technology business.

During the mutual diligence process, I remember telling them multiple times that if they wanted somebody with healthcare experience, I was not the guy. They said they needed someone to build and scale the business, and that they already had enough domain expertise within the company. I didn’t fully understand that then, but I understand it now. Once a company reaches a certain size, like we were at 200 people, you have plenty of domain expertise. What you often lack is the foundational experience needed to take the company to the next level.

I spent seven years building and scaling that company, and we had a successful exit. Between that company, Asparity, and DexCare, I went outside healthcare for two years. When the DexCare opportunity came up, I was excited to return to healthcare, which is something I never thought I would say.

Healthcare is extremely complex, and because of that complexity, it is farther behind other industries from a technology perspective. For someone who likes messy situations and messy industries, it is a good fit because there is a lot that needs to happen. And it feels good to see the impact of the work. I spent seven years building a company in the urgent care sector and saw the direct results. Providers could see more patients and patients were more engaged. I was with that business through COVID and saw the impact our software had on providers and patients.

So I realized I had been missing that feeling in my career. All the hard work you do every day is not only technology. The downstream effect of the work makes you feel like you are making an impact.

Ritu: Yeah, you are genuinely making a difference and I think that is really good. So Matt, it was interesting that you mentioned Providence and how it was spun out of Providence. In our earlier chat, you mentioned this culture of co-innovation where you always worked with your customers to innovate rather than building something and then trying to sell it to them. That was a very interesting and different perspective. We would love to hear more about that co-innovation culture and how you fostered that at DexCare.

Matt: It’s interesting because typically when you think about co-innovation or even customization, that is usually seen as a negative attribute within a SaaS business. Ideally, you build a piece of software and there is as little customization or configuration as possible. Ideally, you take it out of the box and plug it in with every client. That is not realistic in my opinion, certainly within healthcare, but especially for us focusing on large health systems. A one size fits all product will not work. You will not get mass adoption and you will not get full benefit from it.

What is really cool about where we are from a technology perspective is that you can do customization at scale or innovation at scale. Often when you think about innovation, you think of it as a one-time event. You innovate a product and then sell it to all customers. What we are able to do now, and the mentality we have taken at DexCare, is that every single client is innovation. We are innovating for that health system. They all have different priorities, workflows, system capabilities, and data capabilities. We look at innovation on an individual level, coming in and helping innovate using our core platform but making it applicable to their environment.

This is a mindset shift, because often people think this is a barrier to scale. We have proven that is not the case, especially with advancements in technology and artificial intelligence. We can move and process data faster than ever before. We are leaning into this not as a disadvantage but as an advantage, not just for our customers but as a competitive advantage for the company. And I still have to explain that because investors see individual installs at different clients and assume the economics cannot be great. We have proven that is not the case.

Ritu: Okay, great answer. This ties into my next question. With the rapid changes in technology, and even previously, most times technology innovation at a company gets bogged down or does not succeed, not because of the technology itself, but because of cultural issues. People are resistant to change or are entrenched in their ways of thinking. It is interesting that you said you have done innovation at scale and you innovate for every single client. How do you make sure that this culture permeates the company from the ground up and that everybody is bought into that vision? Otherwise, this cannot succeed if people are holding on to old ideas or want to do the same thing each time.

Matt: First, I will point out that this is a journey. I would never suggest that we are at the end point of that. It is a never-ending journey, but yes, it comes down to the people and the leadership. That was something here at DexCare that is interesting because we came out of Providence and took on the second-largest health system in the country, Kaiser Permanente. So in the early years of the company, it was really about staying in pace with our existing customers because they were so large and complex that innovation was pushed to the side. We didn’t have to innovate then. We had a great core product that solved a key problem within health systems, so we focused on taking this product to market at scale.

When you get to the point where we are now, at an inflection point with a great foundation, the question becomes how do we build upon that. That requires a culture shift. There have been a lot of things I have tried to bring to DexCare to do that. One, it comes down to leadership. I tell the team all the time that I want us to fail more. A lot of times that is a head-scratching message, but it is true. If we are not failing, we are not pushing the envelope. You need to fail in a controlled way, and as long as we take an intentional, data-driven approach to the bets we make, not every bet will work out. Creating an environment where that is acceptable sounds easy, but how you show up every day matters. Even taking the little failures and celebrating those helps people realize that failure is progress. You learn more from failures than successes.

When I advise companies, I encourage them to be intentional about creating a culture of learning, and part of learning is failing. Many leadership teams say they support that, but do they really? How they show up each day determines that. So for me, it starts with leadership discipline.

The other important thing at DexCare is that we have had to fill experience gaps. Often companies hire for today’s need because they have a role to fill or capacity to add. In reality, especially for key positions, I look to fill experience gaps, meaning hiring someone who knows where we need to be in two or three years. They have seen it and been through the cycles. They understand what innovation looks like and what failure looks like. If you can get people who have done it before, they can push the innovation envelope because they bring perspective to the team. That is important in creating an innovation culture.

So the two big things that come to mind are leadership mentality and getting key people who have been through it before.

Rohit: That’s definitely a recipe for success, no doubt about it. So Matt, I would like to chime in. You were previously mentioning the infusion of AI across the board in your approach — with your clients and also the product and services the company is offering. Tell us a little more about what DexCare does, how it helps clients, and how you thought about infusing AI into the entire approach and the product and services.

Matt: This is a conversation I have in some capacity every day because AI is an inflection point. It’s arguably the largest one we’ve seen, and it’s evolving at the most rapid pace we’ve ever seen. Before I talk about DexCare, I’ll talk about health systems in general because it’s important to keep that in perspective. You can’t pick up the paper any day without seeing the gold rush of companies doing AI this, AI that.

What’s interesting within healthcare is that there is still a lot of apprehension around AI. Many health systems have set up AI governance committees, so there’s still a degree of education that needs to happen. While AI enables us to do things we’ve never done before, it will take time for health systems and healthcare in general to get comfortable with the risk associated with it. This is real — when you take it to the point of treating patients or using patient data, there is real risk. So it needs time to prove itself. Technology is ready today, but mass adoption will take longer. Health systems are still trying to understand what AI means to their business.

The second thing I’m hearing a lot is that even once AI gives us the data or insight, that’s only part of it. We still need to change the workflow — how we schedule a patient, treat a patient, follow up with a patient. Just having the insight is the starting point. Healthcare is slow to change and very complex. AI can deliver great things, but we need to partner with clients to help them understand what they need to do differently once they have that intelligence. That takes time and is complicated, and there needs to be empathy for what goes beyond the technology.

So how does that translate to DexCare? I don’t look at AI as a project off to the side. It’s quickly becoming standard infrastructure — like a new coding language. The tendency is to chase the next new thing AI enables. At DexCare, we started by asking: how do we just do what we already do, better? More efficiently, with more impact, now that we have this capability?

We took an internal look first: how can we use AI for internal operations? How do we use it to write code better, communicate with customers better? Then we looked at our existing products. Before going off to build new things, what does AI offer to make our current products better? We have a roadmap that goes well into next year that doesn’t necessarily add incremental revenue, but it innovates within our existing products.

Then comes the third part: true innovation. This has completely changed the game. What used to take six months to rapid prototype or build an alpha version, I now have teams doing over a weekend. It scares me — in a good way — because I’m thinking, how do I harness that? I used to expect updates in months. Now they come back in days with an initial version. So we’ve had to rethink our entire product development process — how we go from an idea to shipping product. It has completely changed. Because of the rapid pace, we can fail more, which means we can innovate more.

Going back to co-innovation — clients have very limited time. We’re one of hundreds or thousands of vendors coming to them with ideas. Historically, it’s been a struggle to get mindshare for co-innovation. Now, because we can take ideas and prove or disprove them quickly, it unlocks new opportunities. We can sit with clients, understand their challenges in a one-hour meeting, and come back with a prototype within weeks. It has dramatically condensed the timeline for what we can do.

Ritu: Yeah, that’s what we’re hearing across all clients — both kinds of projects where you’re improving existing things and also thinking completely out of the box for brand-new solutions, like voice agents or agentic AI. Those are the two themes we’re hearing a lot from customers.

Matt: The other lens we’re using at DexCare — and I see this with other companies too — is focus. I’ve been using that word a lot with our teams. We have what we call the three F’s at DexCare: Focus, Fearless, and Fast. Focus is really important because AI enables you to become massively unfocused very quickly. For us, there is enough opportunity staying in the lane we live in — care orchestration. How do we match a patient with the right provider and deal with all the complexity on both sides? There is so much we can innovate within that space that it’s easy, especially with AI, to start drifting outside that lane.

We’re trying to stay focused and take care orchestration to a level our clients and the industry never thought possible. That discipline has benefited us. I talk to other companies that are doing many different things, and at the end of the day, it’s like multiple businesses under one roof. For us, we want to revolutionize orchestration within health systems and don’t have a desire right now to go outside that lane.

Focus is really important. AI can be your worst enemy because it can make you unfocused quickly — and it wouldn’t even cost much to do so. So we’re trying to stay focused on our core mission and value proposition, and use the technology disruption as an advantage, not a distraction.

Ritu: Great. So Matt, you also spoke about the trilemma in today’s world. I thought that was an interesting term, and I think our listeners would like to hear more. If you can tell us a little more about the trilemma, that would be great.

Matt: Yeah, the trilemma is a phrase we coined at DexCare that describes the environment we operate in. From a macroeconomic and administrative perspective, the trilemma is: more patients, fewer doctors, and thinner margins.

The stat we use is that 11,000 people enter the Medicare/Medicaid market every day. At the same time, we have fewer doctors. The projected number of providers leaving practice over the next decade is astounding. And then margins are thinner — so more patients, fewer doctors, and less money.

Going back to care orchestration — the lane we play in — the trilemma is the problem, or opportunity, we’re addressing for health systems. How do we help them get the right patient to the right provider, knowing more patients are coming, expectations are changing, and providers are fewer?

And within “fewer doctors,” there’s another complexity: unused capacity. That’s an interesting challenge. You need more doctors, yet you have unused capacity because of complexity — where data lives, workflows, decision trees. So it feels like fewer doctors are available, even though you’re not using the ones you have to their fullest.

Then the “less money” part — every client I talk to is being challenged to do more with less because of the macroeconomic environment. Margins are thin and getting thinner. That’s why the ROI around DexCare resonates — much of it is efficiency, which is exactly what they need.

The trilemma is something we talk about every day. It’s an easy way to calibrate with someone new: we don’t start with features. We start with the trilemma — more patients coming, staffing issues, and economic strain. From there, it becomes easy to see how the DexCare platform can help.

Rohit: So before we finish the podcast, Matt, we’re coming close to the end of this session. We’d love to have you on again, of course. But for now, any insights or thoughts you’d like to share with the audience? When you look into the future, what do you see coming our way? Any parting thoughts?

Matt: And that’s the best part of that event — everyone in healthcare is there. It’s a nice mix of people from across the healthcare technology ecosystem. I was trying to describe to the company some of my takeaways, and it goes back to something I mentioned earlier: the pace at which things are happening. That’s what everyone was talking about. A lot of the problems or opportunities we’re facing aren’t new, but the pace of change is unlike anything we’ve seen before. It’s exciting and daunting at the same time.

What that pace means is that everyone is rethinking their business. Whether it’s health systems, technology solution providers, or investors — everyone is reassessing what they do and how they do it. It’s fascinating to step back and see that there isn’t a single model to follow. Everyone is reinventing themselves right now.

And because of that, the opportunity to collaborate is incredibly strong. That’s why I enjoy getting out into the market — we’re all rethinking how we operate. Co-innovation really works in this environment because health systems are reevaluating their businesses, and so is everyone else.

With the rate of change and the trilemma we talked about, it’s an exciting time to be doing what we’re doing. I think we’ll see evolution in healthcare over the next two to three years that we haven’t seen in a decade or more. I encourage everyone to lean into collaboration. There’s enough opportunity for all of us. We need to lock arms and figure out, as an industry, how to make care easier to access and better to deliver.

It’s an exciting time to be in healthcare. I never thought I’d be here, but I feel very fortunate because of everything happening in the industry.

Rohit: Amazing. Thank you, Matt, for sharing those insights.

Matt: Yeah, absolutely. Thank you for having me.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Human Centered Leadership is the Real Unlock for AI in Healthcare

Season 6: Episode #189

Podcast with Dr. Felicia Newhouse, Founder, AI-Powered Women

Human Centered Leadership is the Real Unlock for AI in Healthcare

To receive regular updates 

In this episode, Dr. Felicia Newhouse, Founder of AI-Powered Women, highlights the need for human centered leadership as the foundation for AI’s future in healthcare. Reflecting on her near-death experience and two decades in tech, she warns that rapid automation may boost efficiency but often leaves people feeling overwhelmed, disconnected, and burned out.

Dr. Newhouse emphasizes that true progress requires qualities only humans can bring, empathy, intuition, emotional intelligence, and what she describes as “systems awareness” and “systems feeling.” These capabilities help leaders understand the broader human impact of digital tools and design AI that supports well-being rather than replacing human judgment.

She urges organizations to slow down, prioritize dignity and belonging, and adopt AI in ways that strengthen human connection. According to Dr. Newhouse, the real unlock for healthcare will come when AI is guided by compassion, humanity, and mindful leadership. Take a listen.

Video Podcast and Extracts

About Our Guest

With over 20 years as a product tech executive, three successful startup exits, and a PhD focused on women’s leadership and transformational learning, Felicia Newhouse curates spaces where technical fluency meets inner evolution.

Drawing on her work as an energy practitioner and mindfulness-based leader, she integrates evidence-based approaches to human transformation with a deep understanding of consciousness and systemic change. Through the AI-Powered Women Academy and the annual MIT Summit, Felicia unites visionary educators, researchers, and changemakers ahead of their time to ensure women don’t just adapt to the age of AI—they lead it and evolve it with clarity, confidence, and consciousness.


Q: Hi, Dr. Michael Docktor, welcome to our Big Unlock podcast. We are really happy to have you as a guest on our show. Uh, it’s on our sixth season now, and, uh, we are looking forward to this conversation. I’m sure we’ll have a very engaging and interesting conversation about dog health, about healthcare in general, and the new trends about AI and all the buzzwords that people want to hear. Welcome to our show — we’d like to start with introductions. Happy to have you give your introduction. Thank you.

Michael: Yeah, thank you so much for having me. Yeah, I’m Michael Docktor, co-founder and CEO of Dock Health. I’m an ologist by trade. I am now on this, uh, healthcare venture outside of Boston Children’s Hospital where I started my GI career.

I was a busy clinician working on the clinical side as well as in innovation and informatics, and found that we had wonderful tools in the world outside of healthcare and struggled with my own challenges around managing all the tasks that are part of patient care. I found that I was using task management and project management tools that were not built for healthcare.

I scratched my head and wondered why we don’t have these things for healthcare. That was a journey. We started just over five years ago. We spun out Dock Health from Boston Children’s, and we’ve been on a very exciting journey in the world outside the academic walls since then.

It’s been fun. I’m excited to talk to you more about, uh, what we’re doing.

Q Great. That’s a great introduction. Thank you for letting our listeners know. We usually like to start with how you came into healthcare because everyone has an interesting story about what inspired them to become a physician.

For you, it’s particularly interesting because you’ve created this interface between design, technology, and healthcare — and you went beyond just visualizing what you wanted to do or asking why somebody doesn’t fix it, to actually building it yourself. I’d love to hear more about how you came into medicine and then into technology.

Michael: I could probably spend the entire podcast on this question. Obviously, my last name is Doctor, so there was some planting occurring there, and there’s something to be said for that.

One of my earliest memories was wanting to grow up to be a doctor. My younger sister had some GI issues when we were young, and I became very close with her gastroenterologist. I followed her on her journey and, unbeknownst to me, ended up following one of my mentors and was inspired to do the work for other children the way my sister was cared for. That was the initial inspiration.

You mentioned design. That’s interesting because my mother is an interior designer, my father is a dentist who specialized in aesthetics, and design — how things look, feel, and work — has always been part of my DNA. It was an amazing journey to go from being a traditional doctor in pediatric gastroenterology to discovering the importance of user experience and user interface.

Then the iPhone came out, then the iPad, and that really started me on my journey of exploring app development and software, and wondering why we didn’t use these wonderful devices in our pockets the way we should. That journey started more than 10 years ago and has led me to this perfect intersection of healthcare, design, and informatics, creating better experiences for patients and providers.

There’s a lot to unpack there, but people ask me if I would do it differently if I had the chance to do it all over — and absolutely not. I’m doing exactly what I want to be doing right now.

Q: Thank you for sharing that. That gives us so much perspective into how you came into this field, the influence of your parents, and how everyone around you inspired you to do this. That’s really interesting.

That leads us into how you built Dock Health. Tell us some examples of how you saw this becoming transformational in actual implementations with clients. When you built the tool, did you visualize exactly what it would do? Did it go beyond what you thought it would achieve in a healthcare setting? We’d love to hear more about that.

Michael: We’re far beyond where I ever thought we’d be when we first started this journey. That’s the exciting part. Fundamentally, we have such an administrative and operational challenge in healthcare. I saw it firsthand as a busy clinician struggling to manage all the clinically adjacent work that had to be done for my patients.

For example, I might have a patient with Crohn’s disease who needs to go to an infusion center. There are all these downstream tasks and administrative steps that need to be done by a team of people. We didn’t have assistants to do that, and the electronic health record wasn’t built for it.

A quarter of the $5 trillion spent in healthcare goes to administrative and operational challenges, and there really are no tools built for that. We rely on paper checklists, email, faxes, and spreadsheets to manage all the work happening outside the electronic health record.

For me, the realization was that I was using wonderful project management and task management tools to run software projects in my innovation and informatics roles—and yet nothing like that existed in healthcare. Patients, in many ways, are projects. There are tasks that form the essence of care, and they need to be tackled, managed, and collaborated on, with visibility and accountability across teams. That didn’t exist.

What we are now doing is serving as that productivity platform for healthcare, one that sits alongside the electronic health record in synergy, helping manage all the administrative and operational tasks of patient care in ways the EHR wasn’t designed for.

Some examples would be managing patient intake and all the processes associated with it. Referrals, inbound and outbound, with all the paperwork, eligibility checks, and faxes—those workflows are still incredibly manual. Referrals are a great example: 80% of referrals that come into major academic medical centers are still arriving by fax, despite the fact that they’re using Epic, a wonderful electronic health record.

These processes are still incredibly laborious, take too long, and are inefficient. Patient care suffers along the way. There’s a gigantic bottleneck around the administrative and operational work that moves patients through their journeys, and that’s what we’re focused on fixing.

Q: This is what we hear from a lot of our clients and other CIOs and C-suite leaders who come to our podcast—that this is one major problem with healthcare. It’s siloed, and the processes are really stuck in the dark ages.

We were talking to somebody from Athena, and they said they had an 800-person offshore center in India just to screen faxes. When a fax came in, one person looked at it to see if it was a pizza order or a referral. It sounds unbelievable in this day and age, but that’s how it works. I’m amazed to hear this from you as well. It’s remarkable.

Michael: Yeah. In fact, Athena is a partner of ours, and we’re working on referral management. It’s an incredibly antiquated process where everyone loses visibility. The amount of manual labor required to process these things is shocking in this day and age, when they can be handled through process automation, AI, and agents.

Q: Exactly. You’re talking about agentic, we’re talking about voice agents, and yet we’re still dealing with faxes. That’s really interesting to know.

Michael: There is reason to be hopeful. Healthcare is always many decades behind, but the adoption of AI is progressing more rapidly than I’ve seen any technology adopted in healthcare. There’s reason for hope.

Q: That leads into my next question, but before we get there, you mentioned Dock Health as a productivity platform. That’s what it does for doctors, clinicians, and patients. But when we talk to our doctors, clients, and health systems, the one word that always comes up is complexity. They deal with so many different systems and have to learn something new each time.

Where does Dock Health fit in? Is it another system they have to manage, or does it help reduce that burden?

Michael: Yeah, it’s all about reducing the burden and improving the user experience. That’s been fundamental to our belief system since the founding of the company.

First and foremost, we’re trying to become the productivity platform and the hub that handles the administrative and operational work. Instead of being “another system,” we’re often replacing spreadsheets, paper checklists, emails, and faxes—the ways we’ve traditionally managed the 50% or more of administrative and operational tasks required for patient care.

The EHR is great for clinical work, billing, prescribing, and scheduling, but so much happens downstream that isn’t covered. I’d argue we are creating the hub for that. Just as the EHR is the clinical hub, Dock Health serves as the operational hub. Together, it’s really one plus one equals three.

We’re also aiming to be much more consumer-like in our approach. Our tool can onboard a customer in 30 minutes. We offer a free trial, and for small organizations that want to get up and running, they can start using it right away—just like downloading an app. It’s lightweight, highly configurable for end users, and designed with a strong focus on user experience.

The real challenge is that clinicians don’t want another tool. They’re busy and need to spend their time in the EHR. Our core users are often the super users: front office staff, back office teams, operational leaders, and administrative staff who leverage our tool every day.

The important piece is that we connect to the electronic health record and provide visibility for clinicians. If they’re interested, they can see where a patient is in their journey or where a process stands, but they don’t have to be in our system all day, checking tasks or learning another workflow.

The intent is to provide that operational hub for administrative and support staff—the essential members of the care team—while clinicians continue their work in the EHR and often drive tasks into our system through their orders and actions there.

Q: Is the integration with the EHRs native, like with Epic, Cerner, and the big ones?

Michael: Yeah. We’re on the marketplace with a number of the top EHRs, including Epic and Cerner. We’re also working with Mayo Clinic, their Mayo Clinic Platform, and their Deploy platform.

The other thing I’d mention is that many organizations use our tools without being integrated with the electronic health record. That’s often because they’re smaller practices—mental health, concierge care, or primary care—that simply need a hub to handle administrative and operational work and collaborate as a team.

We spend a lot of time helping organizations define their processes, and those processes can then live in Dock, where they can be collaborated on and turned into operational best practices. That’s something that often doesn’t happen in traditional healthcare organizations, and our tool is valuable even when it’s not connected to an EHR.

Of course, the real value comes when we integrate with systems—EHRs, CRMs, patient engagement tools—and serve as the hub while automating as many tasks as possible. That’s when the flywheel starts turning, and organizations begin to feel the benefits of automation and work reduction. It ultimately moves the needle in a measurable way.

Q: So, you’re saying if there’s an integration with the EHR, then it’s end-to-end and people can see a complete view of what’s happening. But even without the EHR, because it helps with workflow management, it’s valuable for practices?

Michael: It’s just like every other industry. They have Asana, JIRA, Trello—all these tools where a lot of the real work gets done. That provides value in itself by giving a clear view into where the patient is in their journey and what process they’re following.

When we integrate with an EHR or other systems, we can then automate those workflows. For example, when a fax comes in, we can launch a workflow for a new patient referral. When a lab order is placed, we can launch a workflow for follow-up. Or when a patient has a procedure, we can launch a process for their downstream follow-up.

Q: That leads into the next question, which is your learning journey with AI. What advice do you have for our listeners about where AI is headed? And with voice agents and agentic tech being buzzwords, where do you see Dock Health going? Are you also looking at implementing voice agents?

Michael: AI is incredibly exciting. I’ve put it out there that we’re an AI-first company. We’ve been thinking about this for a while, and we already have what we call Dock Intelligence in production with customers. We started with the basics, using foundational models and generative AI to process large troves of data.

Now, we can summarize all the work being done for a patient and create a snapshot for the end user—showing all tasks, workflows, patient context, and even clinical context if available. That gives a quick overview of what’s happening. Users can edit that snapshot if needed, or generate a note that writes back to the EHR to keep the operational and clinical record in sync.

That’s the first step in our AI journey. From there, we realized tasks bundle into workflows, workflows can be automated, and now we’re starting to farm out those tasks to agents and AI. For example, a voice agent could follow up with a patient to confirm a referral or review lab results. We’re actively pursuing that, as well as leveraging AI to extract data from faxes to automate referral processes.

AI is the big unlock. In the next three to five years, I believe most administrative and operational tasks will be handled by automation and AI agents orchestrating together. These agents need rails to run on and structure to guide them, and end users must remain in the loop to provide oversight and visibility. But the lion’s share of this work will be handled by agents—and we’re building that future right now.

Q: Are you aligning specifically with any particular LLM or provider, or are you going to be completely agnostic?

Michael: I’d like to think we’ll be agnostic. We’re doing plenty of building on some of the foundational models ourselves, and we’re partnering where we can with great tools. For example, with voice agents, we’re not necessarily building them ourselves—there are excellent options out there. What we are doing is building our own homegrown AI agents that can manage processes and facilitate handoffs from task to task.

Our approach has always been to recognize that there’s a wonderful ecosystem out there. We want to be the hub that connects to the best-of-breed systems—whether that’s Epic as an EHR, Salesforce as a CRM, or other tools we can leverage to create a healthy ecosystem. That’s what we’re pursuing.

Q: I wanted to ask a question about that because with the LLMs, one of the main problems is the hallucinations or the repeatability or the trust factor there. So I saw that Dock is HITRUST certified. So, I just wanted to ask, what are your views on that? Because in terms of using generative AI when we talk to our clients, uh, for implementations on LLMs, or they’re more comfortable certainly with the administrative tasks, but even with the administrative tasks there’s always the question of what are the guardrails you put around that and how do you make sure that the results that you are seeing or you are displaying on Doc Health, you know, stay within that, those bounds of accuracy. Whathat are your thoughts around that?

Michael: AI is incredibly exciting—it’s moving at the speed of light, and everyone wants to benefit from it. I do think administrative and operational areas of healthcare are lower-hanging fruit and far less risky. We’re not yet in a place where we can reliably use AI for absolute clinical decision support and autonomy, though I believe we’ll get there in the not-too-distant future.

For now, the clunky and manual administrative work is ripe for AI. Still, we need to be mindful of potential hallucinations. In our experience so far, we haven’t seen issues, but we’ve put safeguards in place. That means keeping a human in the loop to ensure outputs are appropriate and relevant. We also give users the ability to edit results before they’re sent—whether it’s a summary being emailed to a colleague or written back into the EHR as a clinical note.

It’s essential to show your work. If we’re pulling data from various sources, we show those sources. We keep users in the loop, give them control to review and edit, and maintain tight feedback loops to catch and address anything off.

So far, even foundational LLMs have been surprisingly strong in our relatively narrow use cases. The real challenges will come as we move toward higher-risk clinical decision support—but I’m confident we’ll get there quickly.

Q: It’s interesting you mentioned humans in the loop and the fact that people can review or edit what’s being generated. But with agents, one of the key defining characteristics is autonomy—they can make API calls, send emails, even browse the web to find and act on information. How do you think about that level of control being handed over?

Michael: I think it’s all about balance. The value of task automation and workflow automation is clear. For us, one of our strengths is providing a user interface where the end user can actually see where a process is in its journey.

We’re working on features like showing confidence levels or confidence intervals for data extracted—for example, from a fax. That way, we not only show our work but also give transparency into how accurate that extraction might be. Using our interface, which breaks workflows into tasks, we can show exactly where a process stands. If we believe human involvement is needed, we assign a task and call someone in to review.

Even in the agentic future—which is already upon us and actively being built and tested—we see ways to keep humans in the loop. Operating entirely in a vacuum is risky. Part of my mantra, coming from clinical practice, is that I lacked visibility and accountability in the work being done on behalf of my patients, lost in a black hole of faxes and emails. It’s important to show where the patient is in their journey, where the process stands, whether an agent is handling it or automation is moving data between systems. Giving people visibility and the ability to drill down is critical.

Q: That’s an interesting viewpoint. You mentioned the front and back office and clinicians, but I didn’t realize patients might also have visibility into the system.

Michael: That’s certainly the vision for the future. Right now, our solution focuses on creating visibility and accountability for the care team—clinical and operational staff. But ultimately, the patient is part of the care team too. I would love to see a future where patients are assigned tasks and the rest of the care team has visibility into their progress. I think that’s inevitable. For now, we’re focused on giving the traditional care team the tools they need, but over time, I see patients and their home-based care team being part of that ecosystem.

Q: So I think we are almost at the end of the podcast. We would like to conclude by asking you what you think, maybe give a horizon of like a year and then maybe a five-year horizon. What do you think the top trends that are going to be in AI, and particularly for you at Dock Health? What are the three things that you are really keeping close tabs on and you feel that it’s going to really impact your product and be very transformational.

Michael: It’s tough to predict because AI is moving so fast. Moore’s Law doesn’t apply anymore—the doubling is happening every few months. Everything right now is AI, and “agentic” is the word of the day. I’ve even heard “ambient agents.” We see our role as orchestrating workflows where agents will carry out the majority of tasks.

When we started Dock Health, I imagined a day when it would be smart enough to handle processes automatically. AI has accelerated that roadmap by five to ten years, and the pace keeps shrinking. I truly believe that in the next five years, when healthcare spending in the U.S. reaches $10 trillion, the $2.2 trillion spent on administrative and operational costs may actually shrink because of operational efficiencies unlocked by AI.

We want to give care teams superpowers. Administrative and operational staff deserve better tools to do their work. Just as ambient scribes are now relieving clinicians from documentation, I believe AI will do the same for the administrative and operational burdens in healthcare. Within three to five years, I expect most of that work will be automated. Humans will still play a role, but much of it will feel like it just happens—almost magically.

If you zoom out five years from now, it will look like magic. But by then it will feel obvious. And that excites me, because at the end of the day, patients, our economy, and the world need more efficient care. The fact that we waste a trillion dollars a year on administrative tasks is shameful. Patients are asked to take on too much, like reminding us about referrals or tracking down lab results. These things happen because we’re human and don’t scale well. But now we have incredible tools at our fingertips, and I believe the next few years will be the most exciting time healthcare has ever experienced.

If we zoom out five years from now, it’s going to look like magic—but by then it will feel obvious. I’m excited for that future because, at the end of the day, patients, our economy, and our world need more efficient care. The fact that we waste a trillion dollars a year on administrative and operational tasks is shameful.

Too much of the burden falls on patients. Physicians and care teams often say, “Call me if you don’t get your referral in a couple of days,” or, as I saw with my own mom recently, patients are left chasing down lab results. These things happen because we’re human and we don’t scale well.

Now, we have incredible tools at our fingertips. That’s why I believe the coming years will be the most exciting time in healthcare that I’ve ever experienced—and likely the most exciting time the world has ever seen. Healthcare is primed for transformation and opportunity.

Q: Thank you for being with us on our podcast. It was a wonderful conversation, and we look forward to sharing your vision for the future with our listeners.

Michael: Thanks so much.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

How Virtual Care Is Redefining Physician Capacity, Patient Access, and the Future of AI in Healthcare

How Virtual Care Is Redefining Physician Capacity, Patient Access, and the Future of AI in Healthcare

Insights from Dr. Chris Gallagher on The Big Unlock Podcast

Virtual care is no longer an experiment. It is becoming a core part of modern healthcare delivery. In a recent episode of The Big Unlock podcast, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, discussed the shift toward hybrid care models, how virtual care, tele-ICUs, and AI are reshaping physician distribution, hospital operations, and the patient experience, especially for underserved communities.

Chris’ story is both personal and systemic, rooted in early exposure to underserved communities, years before telehealth entered the mainstream. His experience provides a real-world blueprint for how virtual care models can solve persistent physician shortages, expand specialty care, and create safer, more efficient patient experiences.

From Rural Weekends to Virtual ICU Pioneer

Chris’s journey into telehealth began as a cardiology trainee spending weekends serving rural communities around Dallas, where he saw the same level of disease complexity as in major academic medical centers, often worse because conditions went undiagnosed for years. That experience convinced him that geography should not determine the quality of care, and it sparked a career-long focus on high-acuity, underserved patients.​

When recruitment of on-site specialists failed, he and his colleagues turned to telemedicine, eventually building the first virtual ICU in Texas in 2013. And on its third night, the program helped save a life and cemented his conviction that virtual care needed to be his life’s work.​

Overcoming Early Resistance to Telemedicine

Launching tele-ICU a decade before COVID meant pushing against skepticism from clinicians who questioned whether virtual models were “real medicine”. To win trust, Chris’s team limited their initial efforts to a single ICU for a year, proving safety, outcomes, and ROI before scaling.​

He describes the long stretch from 2014–2016 as mostly educating health systems, with a turning point around 2018 when leaders needed less explanation and more implementation. Then the pandemic accelerated acceptance by at least a decade and normalized virtual care as a core modality.​

Making Technology “Fisher-Price Easy”

One of Chris’s central themes is that technology must be radically simple if clinicians are going to use it in the chaos of real-world care. Early on, a virtual encounter required 27 steps for the physician and 13 for the nurse, which created friction and slowed adoption.​

His team adopted a design mantra – “Fisher-Price easy,” and relentlessly removed steps until clinicians could connect with a patient almost as easily as pressing a single button. As the user experience improved, encounters increased and adoption became self-sustaining, a pattern he believes will repeat with AI if solutions are intuitive and reliable.​

Solving Physician Distribution, Not Just Rural Access

While the origin story was rural underserved care, Chris emphasizes that the main telehealth use case has shifted dramatically. In just three years, Access TeleCare moved from serving 70% rural and 30% urban patients to the reverse – 70% urban and 30% rural.​

Today, virtual programs are as likely to support large city hospitals as small rural facilities, especially where there is only one on-site specialist who can never take a day off without leaving gaps in coverage. Telehealth becomes a “programmatic envelope of care,” adding fractional virtual FTEs around local clinicians so hospitals can achieve 24/7 coverage without burning out the in-person team.​

Virtual Coverage as a New Staffing Model

Chris describes a new staffing paradigm where hospitals no longer try to fully staff every specialty on-site around the clock. Instead, they:

  • Use virtual clinicians to cover nights, weekends, and low-volume periods.
  • Allow scarce specialists (like infectious disease or intensivists) to focus on clinic or procedures while telehealth handles inpatient consults.​

Because 66% of hospital time is nights and weekends, covering everything purely in person is either impossibly expensive or unsustainable for clinicians, whereas virtual care can be scaled “dose-dependently,” used only as much as needed, without idle capacity.​

AI, Automation, and The Digital Back Office

For Chris, AI is not abstract; it is already embedded in practical workflows. His organization is piloting AI in back-office areas such as revenue cycle and operational automations, as well as in clinical routing and scheduling to support nearly 800 physicians and nurse practitioners.​

Over 50% of consults now flow through digital automation rather than phone calls, with EMR-integrated workflows that let hospitals trigger a consult at the push of a button and route it directly to the right specialist’s mobile app. AI will make this routing smarter and faster, enabling his team to reach the bedside up to 20% sooner, crucial for emergencies like acute stroke or cardiac arrest.​

Voice Agents and The Next Wave Of AI

Chris is optimistic about voice agents as a natural evolution in AI-enabled care. His team is actively running pilots with multiple vendors to determine which tools best fit their physicians and advanced practitioners, focusing on both efficiency and experience.​

Most current use cases they are exploring sit behind the scenes – supporting revenue cycle, documentation, and operational workflows, rather than replacing the human interaction at the bedside. The goal is not to remove clinicians from the loop but to free them from administrative burden so they can spend more time in clinical decision-making and patient communication.​

Redefining The Digital Front Door For Acute Care

Unlike many digital health companies that focus on at-home consumers, Access TeleCare’s “digital front door” starts inside hospitals. All of their patients are in emergency departments, ICUs, inpatient floors, or clinics, and many encounters are unscheduled, triggered by sudden changes in condition.​

Instead of patients booking online, hospitals initiate virtual consults directly from Epic or Cerner, routing requests into a centralized platform that balances workload among specialists in seconds. This model turns telehealth into an invisible backbone of acute care, embedded in hospital operations rather than acting as an external service layer.​

Making Virtual Care Feel Like In-Person Medicine

To win clinician and patient trust, Chris insists that virtual encounters must feel as close as possible to traditional bedside care. Each hospital is equipped with a six-foot telemedicine cart featuring a large display, high-resolution zoom camera, and digital stethoscope so remote physicians can read monitors, view ventilator settings, and perform detailed physical exams.​

There is always a “patient presenter” in the room – usually a nurse, medical assistant, or ER physician – to provide hands-on support and carry out parts of the exam, while the remote physician documents, orders, and manages treatment within the hospital’s EMR as any on-site clinician would.​

Health Equity, Local Care, And Cost Savings

A major impact of these programs is on equity and local access. Around 82% of the patients Access TeleCare serves are underserved, including uninsured, Medicaid, and elderly populations who would otherwise face delayed or fragmented care.​

By bringing specialists to the bedside virtually, hospitals avoid costly transfers that can add about $5,000 per episode and, in the case of helicopter transports, tens of thousands of dollars more—costs that ripple through families and communities. For roughly the price of a $200 telemedicine consult, hospitals can keep patients in their home communities, close to their support systems, while still delivering high-quality specialty care.​

Toward A Virtual-First, Hybrid Future

Strategically, Chris sees health systems moving toward “virtual-first” models in many non-procedural specialties. In this vision, every patient is guaranteed baseline access to specialty care via virtual providers, and in-person clinicians are layered on top for procedures and high-volume needs.​

He argues that traditional physician staffing models, largely unchanged for a century, are no longer tenable in an era of workforce shortages and rising demand. Virtual care provides the flexibility to dial resources up or down, matching supply to demand without overworking clinicians or paying for idle capacity.​

A Turning Point for Medicine

Chris places AI and virtual care alongside antibiotics and modern surgical techniques as potential turning points in medical history. COVID, he notes, didn’t just accelerate telehealth adoption—it fundamentally lowered healthcare’s resistance to change and opened the door for broader digital transformation.​

He is bullish that AI will significantly enhance organizational efficiency, improve the physician experience, and ultimately elevate patient care, provided that governance, privacy, and safety guardrails are in place. For Chris Gallagher, the future of healthcare is hybrid, AI-enabled, and deeply human—using technology not to replace clinicians, but to extend their reach to every patient who needs them, wherever they are.

Virtual-First Care Starts with Making Technology Effortless

Season 6: Episode #188

Podcast with Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare

Virtual-First Care Starts with Making Technology Effortless

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In this episode, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, shares valuable insights on the evolution of AI, how virtual care is reshaping access, staffing, and costs across health systems, and why making technology effortless is the key to driving a successful virtual-first care strategy.

Chris recounts the pioneering achievement of building the first virtual ICU in Texas in 2013, which quickly proved life-saving and marked a turning point in virtual health adoption. He discusses how they are addressing physician distribution issues by augmenting in-person staff, shifting its focus from predominantly rural to 70% urban facilities by offering essential 24/7 virtual specialists to care teams. Chris stresses that solutions must be effortless for clinicians, “Fisher Price easy,” so adoption becomes self-perpetuating.

Chris highlights AI’s immense potential to improve efficiency, enhance physician experience, and expedite patient care, especially through automation and a future “virtual-first” healthcare strategy. Take a listen.

Video Podcast and Extracts

About Our Guest

Chris Gallagher, M.D. is the Founder and Chief Strategy Officer of Access TeleCare. As a cardiologist in rural Texas hospitals, Dr. Gallagher noticed that timely care was one of the most important variables in a favorable patient outcome. However, this was not happening consistently across hospitals.

So, he started looking for a virtual solution that could ensure the delivery of high-quality, timely care. When he didn’t find it, he built it.

As founder of Access TeleCare, the nation’s largest high-acuity telemedicine provider, Dr. Gallagher brought his experience in internal medicine and cardiology to pave the way for tech-enabled clinical networks. Today, Access TeleCare is the standard bearer of excellence in telemedicine, a 2024 Top Remote Workplace, operating virtual care programs in all 50 states across 8 medical specialties, with a virtual catchment area of over 216 million Americans (across 15,000+ zip codes) representing roughly 65% of the U.S. population.

In his role as chief strategy officer, Dr. Gallagher drives innovation, identifies strategic partnerships, and plans for the company’s strategic growth.

Dr. Gallagher trained at UT Southwestern for his Internal Medicine Residency and Cardiology Fellowship and earned his Doctor of Medicine from Texas Tech University School of Medicine. He is a fellow in the American College of Cardiology and a member of the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Medical Association, and the Texas Medical Association.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

How Rush University System for Health Is Advancing Generative AI Innovation and Digital Transformation

Digital transformation in healthcare has accelerated dramatically over the past few years, driven by changing patient expectations, demographic shifts, and rapid advances in artificial intelligence. At the center of this transformation is Rush University System for Health, a Chicago-based academic health system known for its clinical excellence and forward-thinking approach to innovation. In a recent episode of The Big Unlock podcast, Anil Saldanha, Chief Innovation Officer at Rush University System for Health, offered a wide-ranging look at how the organization is advancing generative AI, expanding digital care models, and tackling systemic health inequities.

Anil’s role sits at the intersection of public health, community health, and care delivery – an ideal vantage point for understanding how technology can reshape health outcomes. His insights highlight not just where Rush University System for Health is today, but where healthcare as a whole is heading.

A Virtual-First Foundation for Digital Transformation

One of the most visible components of digital transformation at Rush University System for Health is the shift toward a virtual-first ecosystem. While the pandemic accelerated telehealth adoption nationwide, Rush took the momentum and built an intentional strategy around it.

Anil explained that Rush began by strengthening virtual primary care, followed by virtual urgent care and specialty care. The virtual urgent care service stands out for its ability to address more than 40 different conditions with a waiting time as short as 20 minutes. Patients who once needed to travel to a clinic for issues like cough, rashes, prescription refills, minor infections, or follow-up questions can now get the care they need from home.

Virtual specialty care has expanded across eight service areas, helping patients access high-quality clinical expertise without the typical logistical barriers.

This virtual backbone laid the groundwork for one of Rush’s most innovative offerings: Rush Connect Plus, a subscription-based service that reflects new consumer expectations in healthcare. Through Rush Connect Plus patients anywhere in the United States can get 24/7 access to a care team, digital triage support, referral pathways, and seamless connection to Rush specialists. As Anil explained, many younger patients “are not interested in having a dedicated primary care provider. They want care whenever they need it, wherever they are.” Rush Connect Plus reflects this shift and meets patients on their terms.

 

Addressing Chicago’s Life Expectancy Gap Through Data and Community Strategy

While digital convenience is important, Rush’s transformation is equally focused on tackling some of Chicago’s most deeply rooted public health inequities. The Chicago “death gap,” an extreme difference in life expectancy between neighborhoods, has long been a defining challenge for the city.

Anil described it clearly: “If you take four subway stops west of Michigan Avenue, life expectancy drops by 16 years. In the south of Chicago, it drops by 30 years.” Rush has made it a corporate mission to reduce this gap by 50% by the year 2030.

Several factors drive this disparity, including cardiovascular disease, cancer, firearm injuries, stroke, and uncontrolled hypertension. The social determinants of health adds another layer of complexity. To address these issues systematically, Rush secured a $7.5 million grant to build a Health Equity Analytics Studio, an advanced data environment designed to unite clinical data, census information, wearable insights, and community metrics into a single analytical foundation.

This ecosystem of data will allow Rush to identify “hot zones” of chronic disease risk across the region. The goal is to provide public health teams, community health workers, and clinical service lines with actionable insights so they can deliver targeted, high-impact interventions.

In Anil’s view, this kind of population-level digital infrastructure is essential for equity: “This will be a major digital aid for our public health and community health departments and help us understand the complex chronic care needs of our population.”

 

Transforming Cancer Care Through Early Detection and Strategic Collaboration

Cancer care has been another area of exceptional focus at Rush, supported by both clinical partnerships and bold technological initiatives.

A key strategic collaboration is Rush’s partnership with MD Anderson Cancer Center, widely recognized for world-class oncology care. Through this partnership, Rush has established several Rush MD Anderson Cancer Centers across the Chicago region, enabling patients to receive cutting-edge treatment and participate in advanced clinical trials without traveling to Houston. As Anil noted, this partnership ensures that “our patient population doesn’t have to travel to Houston to take advantage of MD Anderson’s excellence.”

Complementing this is Rush’s pioneering move into multi-cancer early detection. About a year ago, Rush began offering the Grail liquid biopsy test, which can identify more than 50 cancers and many of which have no other detectable biomarkers.

Anil described the decision to adopt Grail as a “bold bet,” grounded in scientific promise and clinical necessity. Despite the $750 out-of-pocket cost and lack of FDA approval, community demand has been overwhelming. “We’re not able to keep up with the demand,” he shared. Rush has systemized referral pathways and follow-up procedures to ensure patients receive timely support if they receive a positive signal from the test.

For Rush, early detection represents a shift in how society invests in cancer care. Instead of devoting most resources to end-of-life treatment, Anil and Rush’s CEO, Dr. Omar Latif, emphasize the need to invest earlier in the patient journey to prevent severe outcomes. This philosophy aligns with Rush’s broader mission of prevention, equity, and long-term community health.

 

Generative AI at Rush Health: Thoughtful Deployment and Research-Driven Innovation

Generative AI is becoming one of the defining forces in healthcare transformation, and Rush is embracing it with both enthusiasm and caution. Anil made it clear that Rush wants AI to enhance, not replace, clinical expertise and patient relationships.

Ambient listening technology is one area where generative AI is already making an impact. Rush uses Suki to reduce clinical documentation burden, allowing providers to focus more on patient care. Rush also deploys an AI-driven symptom checker across its website and mobile app, helping patients navigate symptoms and access appointments more efficiently.

One of the most groundbreaking, and lesser known, AI initiatives at Rush is the Socrates behavioral health kiosk, part of its RODO program supporting veterans with PTSD. The kiosk uses a multi-agent AI system built on OpenAI models. Patients interact with an AI therapist, while an AI rater and a third monitoring agent work behind the scenes to prevent hallucinations, avoid looping behavior, and maintain clinical relevance.

Anil highlighted the importance of this multi-agent design: “It allows us to make changes in real time to ensure looping doesn’t happen and hallucination concerns are mitigated.” While still in a research environment, Socrates represents a promising direction for behavioral health innovation at a time when staffing shortages persist across the country.

Beyond behavioral health, Rush is monitoring advancements in diagnostic AI, such as cardiovascular algorithms, vision-based imaging tools, and cancer detection systems. Saldanha views these developments as signs of a “hopeful” future, where traditional machine-learning models and generative AI will coexist to support clinical care.

 

Looking Ahead: A Connected, AI-Enabled Future for Care Delivery

When asked about what’s next, Anil spoke about the emergence of hospital-at-home programs and ambulatory-first models, reflecting a broader movement toward decentralizing care. He expects generative AI to play a growing role in patient education and preparation, a trend already visible in clinics.

He referenced a recent story of a patient who used ChatGPT to learn about a “Tilt Table Test” before coming in for vertigo. The clinician was surprised by the level of detail and preparation. For Anil, this is a sign of what he calls a “connected care ecosystem,” where patients become empowered partners in their own care.

“Patients are partners in their care,” he said. “The more they’re empowered and educated, the better society will be.”

 

A Model for the Future of Healthcare Transformation

Rush ’s journey reflects the intersection of technological progress, clinical innovation, and community responsibility. Through virtual-first care, generative AI adoption, early cancer detection, and data-driven equity initiatives, Rush is building a healthcare model that is not only future-ready but deeply human.

Anil concludes the podcast episode with optimism: “Healthcare affects all of us. Don’t give up on it. Be part of the solution in whatever way you can.”

The digital transformation at Rush, and its thoughtful use of generative AI, offers a powerful blueprint for any organization striving to deliver smarter, more equitable, and more connected care.

A First Look at Our New Book: Generative AI — Unlocking the Next Chapter in Healthcare

The Beginning of a New Era

When we began writing Generative AI: Unlocking the Next Chapter in Healthcare, we set out to capture a moment we could feel unfolding all around us. Hospitals were experimenting with generative models to summarize clinical notes. Pharmaceutical teams were using AI to design molecules. Patients, whether through voice agents, virtual coaches, or precision-care tools, were starting to experience medicine that learns from them in real time.

Healthcare has always evolved with technology, but something about generative AI feels different. It doesn’t just automate; it collaborates. It drafts, hypothesizes, and reasons. It changes how humans and machines think about each other and with each other.

Our goal was to document this transformation honestly, its potential and its pitfalls, and to offer leaders a practical framework for navigating what might be the most consequential technological shift in medicine since the discovery of antibiotics.

Inside the Book

In the opening chapters, we invite readers to step into the clinical frontier of this technology. Here is a brief passage from Chapter 1:

“The first wave of AI in medicine focused on detection, spotting a tumor, predicting a lab value, flagging an anomaly. The next wave, powered by generative models, focuses on creation, drafting treatment plans, designing trials, even writing the code that powers health systems themselves.”

Another early excerpt explores how this evolution is changing the physician’s daily experience:

“When an algorithm can generate a differential diagnosis or summarize a complex chart, it doesn’t diminish the clinician’s value. It redefines it. The new skill set is interpretive intelligence, the ability to question, contextualize, and apply machine-generated insight with empathy.”

Throughout the book we weaved together interviews, case studies, and lessons from our work at BigRio and Damo Consulting. Readers will find examples ranging from AI-assisted radiology and conversational triage tools to synthetic data pipelines accelerating clinical research.

But we also look beyond the technology. Each chapter ends with a reflection on governance, ethics, and human trust, because AI’s success in healthcare depends as much on values as on code.

From Algorithms to Empathy

One of our favorite sections explores the paradox at the heart of digital medicine: how machines that generate text, images, or predictions can actually restore the human connection in care.

“The gift of automation is time; the one resource healthcare professionals never seem to have enough of. When AI writes the discharge summary or reconciles the medication list, the clinician gets something priceless back: more time to give to the patient’s story.”

Generative AI, when properly implemented, becomes a quiet collaborator that amplifies compassion instead of replacing it. That vision runs through every chapter of our book.

Why This Book, Why Now?

We’re often asked what inspired us to write this book at this particular moment. The answer is urgency.

In 2025, healthcare organizations are under unprecedented pressure to modernize. They face clinician burnout, labor shortages, and an avalanche of unstructured data. At the same time, generative AI technologies are moving faster than regulation, raising new questions about bias, safety, and transparency.

We saw a need for a resource that bridges innovation and accountability. A guide written by those of us who have built AI systems inside real healthcare environments, not just in research labs.

Our message is simple:

  • The technology is powerful, but context matters.
  • Generative AI can democratize expertise, but only if governed ethically.
  • Healthcare’s next chapter must combine precision with empathy.

This is not a manifesto for automation; it’s a blueprint for collaboration. It is about ensuring that, as AI learns to write prescriptions or generate treatment options, humans remain the authors of care itself.

The Collaboration Behind the Pages

Writing together allowed us to merge two complementary perspectives. Rohit brings systems-architecture and data-science lens from decades of work in health IT and consulting. Ritu brings leadership and education focus, guiding organizations through responsible adoption and change management.

Our shared mission—reflected in the book and in The Big Unlock podcast—is to make AI accessible and actionable for healthcare executives, innovators, and clinicians alike.

We wanted the book to feel both visionary and grounded: rich in insight but practical enough that a hospital CIO, a data scientist, or a medical student could, or even a patient, could all find value in it.

Looking Ahead

As the launch approaches, we’re encouraged by the early enthusiasm from reviewers and peers who describe Generative AI: Unlocking the Next Chapter in Healthcare as “a rare combination of technical rigor and human empathy.”

In the coming months, we’ll continue the conversation through live webinars, podcast interviews, and case-study spotlights drawn from the book. Our hope is that this work sparks collaboration across disciplines and across the globe on how to responsibly unlock the full potential of Generative AI in medicine.

Order and Launch Details

Generative AI: Unlocking the Next Chapter in Healthcare
By Rohit Mahajan and Ritu M Uberoy
Published by Taylor & Francis Group
Available November 17, 2025, in soft cover, hardcover, and eBook formats.

Order or learn more at the official author webpage.

Generative AI: Unlocking the Next Chapter in Healthcare

Generative AI: Unlocking the Next Chapter in Healthcare

New Book Provides Insider Insight on the Impact of Generative AI on Healthcare!

CAMBRIDGE, Mass.Nov. 13, 2025 /PRNewswire-PRWeb/ — Artificial intelligence is no longer a future promise in healthcare, it’s the driving force behind how care is delivered, research is conducted, and data is transformed into lifesaving insight. A groundbreaking new book, Generative AI: Unlocking the Next Chapter in Healthcare, [ISBN: 9781041125693], published by Taylor & Francis Group, explores this evolution and what it means for clinicians, researchers, innovators, and policymakers worldwide.

Authored by Rohit Mahajan and Ritu M Uberoy, leading voices in healthcare technology and digital transformation, the book demystifies how generative AI and Agentic AI are reshaping patient engagement, drug discovery, diagnostics, and the very fabric of clinical decision-making.

Mahajan and Uberoy draw upon decades of experience driving AI innovation at BigRio and Damo Consulting. Through real-world case studies and expert insights, the authors examine how hospitals, payers, and life sciences organizations can responsibly implement generative AI to enhance both efficiency and patient care in healthcare delivery.

Mahajan and Uberoy draw upon decades of experience driving AI innovation at BigRio and Damo Consulting. Through real-world case studies and expert insights, the authors examine how hospitals, payers, and life sciences organizations can responsibly implement generative AI to enhance both efficiency and patient care in healthcare delivery.

The most balanced and forward-thinking treatment of generative AI in medicine to date.

“Healthcare stands at the crossroads of innovation and compassion,” said Rohit Mahajan, CEO of BigRio and Damo Consulting. “Our goal was to provide a playbook that helps organizations harness AI not just to cut costs but to elevate care quality and human connection.”

Co-author Ritu M Uberoy added, “We wanted to move the conversation beyond hype. Generative AI isn’t about replacing clinicians or healthcare decision makers, it’s about giving them superpowers through technology that learns, reasons, and collaborates.”

The book provides an accessible yet technically grounded guide to AI governance, data ethics, regulatory implications, and the emergence of agentic AI systems.


Early Reception

The release of the book comes at a pivotal time. Healthcare systems globally are accelerating digital transformation while grappling with workforce shortages and data fragmentation. Analysts forecast that AI-driven solutions could save the U.S. healthcare system more than $360 billion annually by 2030 through automation, improved diagnostics, and streamlined administrative tasks.

Early reviewers have praised the book as “the most balanced and forward-thinking treatment of generative AI in medicine to date.”

Industry thought leaders and academic reviewers note its blend of technical insight, ethical reflection, and pragmatic leadership advice.


About the Authors

Rohit Mahajan is the author of Quantum Care: A Deep Dive into AI for Health Delivery and Research, a number one Amazon bestseller exploring how AI is transforming healthcare. He is the Founder and Managing Partner at Saviance Technologies and serves as CEO of both BigRio and Damo, where he leads innovation in AI and digital health transformation.

Rohit co-hosts The Big Unlock podcast with Ritu M Uberoy, engaging senior healthcare leaders in conversations about the future of care delivery. In 2025, he received the GHLF Global Impact Award for Digital Health Innovation in recognition of his contributions to the field.

Ritu M Uberoy is a technology executive, entrepreneur, and educator with over 25 years of experience in the global software and IT industry. As Founder of Saviance Technologies and Managing Partner at BigRio and Damo Consulting, she leads digital transformation initiatives across healthcare and life sciences.

Ritu heads the Generative AI Center of Excellence at BigRio and the DigiMTM Digital Maturity Model at Damo, guiding healthcare organizations in adopting AI at scale. She is also the co-host of The Big Unlock podcast and a recognized voice in healthcare innovation.


Publication & Availability

Generative AI: Unlocking the Next Chapter in Healthcare is published by Taylor & Francis Group and will be available November 17, 2025, in print and eBook formats through Amazon, Barnes & Noble, Taylor & Francis (ebook only) and other online retailers. Discounts are available for bulk purchases through Taylor & Francis. For price quotes, please contact [email protected].

For more information or to join the launch mailing list, visit the official authors’ webpage.


About the Taylor Francis Group

Taylor & Francis Group partners with researchers, scholarly societies, universities and libraries worldwide to bring knowledge to life. As one of the world’s leading publishers of scholarly journals, books, eBooks and reference works our content spans all areas of Humanities, Social Sciences, Behavioral Sciences, Science, and Technology and Medicine. From our network of offices in Oxford, New York, Philadelphia, Boca Raton, Boston, Melbourne, Singapore, Beijing, Tokyo, Stockholm, New Delhi and Johannesburg, Taylor & Francis staff provide local expertise and support to our editors, societies and authors and tailored, efficient customer service to our library colleagues.


About BigRio

BigRio is a leading AI, Gen AI, Voice Agents, Data and Analytics professional services company. We are focused on Healthcare, Pharma, Digital Health, Provider, and Payer Industry segments with several innovative solutions. For more information, visit us at bigr.io.


Media Contact

Rohit Mahajan, The Big Unlock Podcast, 1 (857) 557-4302, [email protected]https://thebigunlock.com/

SOURCE The Big Unlock Podcast

Technology Must Remain Invisible, Yet Empower Caregivers to Deliver Care Better

Season 6: Episode #187

Podcast with Charles E. Christian,
Vice President of Technology and CTO, Franciscan Health

Technology Must Remain Invisible, Yet Empower Caregivers to Deliver Care Better

To receive regular updates 

In this episode, Charles E. Christian, VP of Technology and CTO at Franciscan Health, shares reflections from his five-decade journey in healthcare IT and how Franciscan is blending mission, compassion, and innovation to transform patient care.

Chuck explains how the health system is approaching AI adoption through strong governance and a clear focus on solving real problems, from reducing clinician burden to enhancing care delivery. He highlights several key initiatives, including voice agent pilots that help physicians reclaim after-hours time, a Tech Innovation Lab that allows teams to safely experiment and “fail fast,” and a virtual nurse mentoring program that connects senior nurses with new graduates for real-time guidance.

Chuck states that technology should serve, not distract, and the true goal of digital transformation is to enable better care for people. Take a listen.

Video Podcast and Extracts

About Our Guest

Mr. Christian is the Vice President of Technology and CTO for Franciscan Alliance, a thirteen (13) hospital system serving Indiana and Illinois.

Prior to joining Franciscan Alliance, Mr. Christian served as the Vice President of Technology and Engagement at the Indiana Health Information Exchange, the largest and oldest HIE in the country. Mr. Christian also served as the Vice President / Chief Information Officer of St. Francis Hospital, a free-standing, acute care, community hospital in west Georgia, a position he held for 2.5 years. Before his role at St. Francis, Mr. Christian served as the Vice President / Chief Information Officer for Good Samaritan Hospital, in Vincennes, Indiana. A position he held for almost 24 years. Before joining Good Samaritan Hospital, Mr. Christian worked in healthcare IT for Compucare and Baxter Travenol, in both management and implementation roles. Mr. Christian started his career in healthcare as a Registered Radiologic Technologist, serving in various Radiology roles for 14 years.

Mr. Christian holds a degree in Radiology Technology from Gadsden Community College and studied natural sciences at the University of Alabama in Birmingham.

Mr. Christian has delivered presentations on wide range of healthcare technology topics and is frequently quoted and published in national trade publications. He and co-authors, Judy Kirby and Steve Bennett published “Make I.T. Known-Marketing Strategies and Cases Studies in the Healthcare Environment.” Mr. Christian is also a frequent author in Modern Healthcare. Mr. Christian is also the author of the Irreverent-CIO health care blog. Mr. Christian has also authored chapters in multiple published management and college level textbooks.

Mr. Christian is a Life Fellow of the Healthcare Information and Management Systems Society (HIMSS) and is a Past Chair of the HIMSS Board of Directors, and past Chair of the HIMSS BOD Executive Committee. Mr. Christian was previously a member of the HIMSS Analytics Board of Directors. Mr. Christian is a Life Fellow and charter member of College of Health Information Management Executives (CHIME) and served on the CHIME BOD from 2003 through 2004 during which time he chaired the Membership Committee of the CHIME BOD. Mr. Christian is credentialed by CHIME as a Certified Healthcare CIO (CHCIO) and a Certified Digital Health Executive. Mr. Christian is a charter member of the re-established Indiana Chapter of HIMSS and served as a BOD member from 2000 - 2009. Mr. Christian served as a member of the Executive Advisory Board for Advance for Health Information Executives magazine. Mr. Christian served as a member of the Board of Directors of the Indiana Health Informatics Corporation by appointment of Indiana Governor Mitch Daniels. Governor Daniels also appointed Mr. Christian the Indiana Healthcare Information Technology Board of Directors.

Mr. Christian served as the CHIME Foundation Board of Directors as Chair and is the Past-Chair of the CHIME Board of Directors. Mr. Christian has served as the Chair of the CHIME Policy Steering Committee and continues to serve as a contributing member and is the Past-Chair of the SHIEC Advocacy Committee and is a past member of the Indiana HIMSS Chapter Board of Directors. Mr. Christian served on the Georgia HIMSS Board of Directors from 2013-2015, the KLAS Advisory Group from 2009-2013, and the CDW-Healthcare CIO Advisory Council from 2005-2010. Mr. Christian served the AHA Strategic Development Advisory Committee as a charter member. Mr. Christian is a past member of the Symantec Healthcare Advisory Group, and several other industry advisory groups/councils. Mr. Christian currently serves on the Virtustream Customer Advisory Board, the Hyland Executive Advisory Council, the Fortinet Advisory Board, HealthsystemCIO Board of Advisors and a member of the Indiana Hospital Association Information Management Council.


Charles: I am Chuck Christian. I’m the Vice President of Technology and CTO for Franciscan Health. Franciscan is a 12 or 13 hospital system, depending on how you count them. We cover a swath of the Midwest from just south of Indianapolis all the way to Chicago, basically following the I-65 corridor.

We have between 350 and 400 locations, including physician practices, imaging centers, lab draws, urgent cares, and oncology centers. It’s a pretty large organization. We have about 29,000 team members, both employees and contractors, at Franciscan Health.

We are truly mission focused. We are a Catholic healthcare system with a big C. We are owned by the Sisters of St. Francis of Perpetual Adoration. That means there are two sisters in the chapel praying for whatever they deem important and anything we ask them to pray for, 24 hours a day, seven days a week, 365 days a year. That’s where the “perpetual adoration” comes in.

We are a mission-driven organization. I believe in that. A lot of our hospitals are smaller and in underserved places, and we take care of that patient population. I think we’re really good at it.

I’ve known this organization almost 40 years. The CIO previous to Charles, who is our current COO, was a good friend of mine. I was CIO of a hospital in Southern Indiana for 24 years, and Bill and I ran a similar software stack. I watched Bill and learned a lot from him as far as how he ran this large organization.

I’ve been here for six years. I joined in April of 2019, so in dog years that’s like 35 years or more. We are very busy. I’m very blessed to have an outstanding team that manages all this, and I get to stand in awe and watch everything we accomplish every day.

Rohit: That’s fabulous. Thank you, Chuck for that intro.

Ritu: My name is Ritu Roy, and I’m the Managing Partner here at Damo and BigRio, and also the co-host of The Big Unlock podcast with Rohit. Thank you for being our guest today, Chuck. We are looking forward to an engaging and insightful conversation. With that, we can dive right in and get started.

Charles: Thank you.

Rohit: Hi Chuck. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. It’s great to have you on the podcast. Like Ritu said, we’re looking forward to an engaging discussion. I’d like to start with the first thought on my mind. You’re in a mission-driven organization, and you’ve been a healthcare leader for many years. What started you on this journey? Tell us how you got started in healthcare, what attracted you, and what you’re passionate about.

Charles: Well, it depends on how far back you want to go. I’m an X-ray tech, radiologic technologist if you want to use the term. The first 14 years of my career were in radiology.

I stepped out of high school on June sixth in 1971, and on June seventh I stepped into the hospital, and I haven’t left since. Interesting enough, I did a lot of things in the radiology department and became part of the management team of that department. I guess if the chief tech had not been just a few years older than me, I’d still be there, because that was the role I wanted. But Roy just retired a few years ago, and I wasn’t going to wait that long.

I’m a geek, I’m a nerd. I was a nerd in high school. It wasn’t cool to be a nerd in high school back then, but it’s cool to be a nerd now. I did a lot of programming classes on the old System Threes with punch cards. Then I learned how to code for Z80 processors.

When we started automating hospitals back in the mid-eighties, I got chosen to run the ambulatory implementation of order management after we had put in patient management. I realized I liked it, and I knew that was where healthcare was going. Radiology has been a high-tech department in hospitals for a long time. I was trying to automate the patient record in radiology, but it was so expensive I couldn’t get any funding for it.

So I jumped ship and moved over to the vendors for about five years. Eventually I was asked to move to either an implementation manager role or the director of an outsourced IT department in southern Indiana. I did that. I had four daughters at the time, and it was the right thing to do because it was a great place to raise my girls.

I spent 24 years there. It was during the time the role of a healthcare CIO was defined. When I left that job, I was Vice President and CIO. I moved to Georgia to a health system there as Vice President and Chief Information Officer. Then I came back to Indiana and worked at the Indiana Health Information Exchange, which is now the only exchange in Indiana. I had been involved with it since 2005. I worked there for a little over four years, and then I took this role here. That’s my stint in healthcare, which has spanned over 50 years.

Rohit: That’s awesome, Chuck. You’ve been there, done it, and seen it as well. I was curious because a few days ago, when we were chatting, you were talking about being either back from UGM or about to go there.

We all know it’s a week-long affair, people go deep, and there are so many things to cover. We were wondering if you could share some of your experiences or a heads-up on topics you see coming our way.

Charles: Sure. I came home with a great deal of anxiety because of trying to figure out how we’re going to do everything and where healthcare is going. The nice thing about Epic is they now cover the entire gambit. I remember when Epic started; they were only in the ambulatory space and then only in large academic medical centers. They cover quite a scope of product these days.

Now that they have grown the applications, they have de-identified shared data, which I think is going to be a plus. The two-letter acronym was everywhere, AI, and how it’s going to be leveraged and used. They did a nice job showing scenarios of how it could be used and how organizations are using it.

We’re a risk-averse organization. We’re taking a more moderated approach. We’re getting our governance in place first. We already have a few things going through the AI mill, and we will have more. We split it into two pieces, one on the clinical side and one on the operational side. Epic has both, and I think they’re well positioned to do that work. They partner with Microsoft, and they continue to do so.

They announced they are working on their own ambient listening. They have business partners already, but they are creating their own product. I assume it will be predicated on the Microsoft stack, but they didn’t say, so I don’t know.

They also mentioned they are working on their own ERP and starting with workforce management. That makes sense because the workforce is in Epic all the time. Nursing staffing, scheduling, shifts, and how all that ties together. It’s an interesting leap.

Years ago, when Lawson, before being purchased by Infor, said they would create a patient accounting platform, I was in a CHIME focus group. When they mentioned that, a bunch of CIOs in the room asked why they would do that. You need to get your ERP right first. But I think the way Epic is approaching it makes sense.

It was great. I was there for about four days and spent most of the time listening to presentations. Judy did a great job with a big screen about what’s next and what’s coming. The rest of her team did a great job showing what you can do now and what’s coming. They do a good job setting expectations around timelines. They release quarterly. We do two a year, so we’re current from their perspective but behind. We don’t have the wherewithal to immediately adopt everything when they release it, so we have to plan accordingly.

Ritu: Yeah. So Chuck, when I was reading about the UGM, it was interesting because they said their unique proposition with AI is the de-identified patient records they have in Epic Cosmos, which is more than 15 billion patient records. They said that for the first time, it can actually move toward healthcare rather than sick care because doctors can predict trends. And I think they released two new things called Emmy and Penny, which will help doctors see the trajectory of what is going to happen with patients.

So I was curious about your thoughts because you’ve been in this industry for such a long time. Do you think that this USP—this huge bank of patient records—is really going to set them on a differentiating path compared to all the other AI startups trying to do the same thing?

Charles: I think that having the data is huge, honestly. It reminded me a lot of—if you remember years ago—they had a thing called PatientsLikeMe, where people with unique and rare diseases could find others and compare notes and treatment approaches. Working at the Indiana Health Information Exchange, I know they have about 30 years of data. Not all of it is discrete, but the majority is.

One question I asked the CEO, who is a friend of mine—and a lot of researchers use that de-identified data—is that when you create an AI model and just let it learn, there are all kinds of interesting determinations you can make once you have the data. So I think it’s going to be a game changer. Epic is also trying to outdo themselves. Given the market of EHR vendors, there aren’t many left standing. There are three or four. Others are creating similar repositories, but I’m not sure they have the long-term vision or the wherewithal to get it done. Knowing the talent Judy has pulled together, I think it will be very interesting to see what comes down the pike.

Ritu: Thank you.

Rohit: Chuck, you mentioned you’re taking a conservative approach to AI adoption and setting governance before taking major steps. How do you think about innovation or typical problem-solving—for example, reducing cognitive load across the organization? How do you balance this conservative approach with the fast-paced changes happening in the marketplace?

Charles: I think we have to be very clear about what problem we’re trying to solve. There are so many solutions being thrown at us—“Hey, we can do this, we can do that”—but often it’s not a problem we actually have. So we’re trying to pick and choose which targets to shoot at.

I’m married to a critical care nurse, so I’m very careful about getting in the way of the nursing staff. She’s retired, but for me, technology needs to be invisible. If it gets in the way of people being able to do their job, then it’s a problem.

If you think about it for a minute—and I’ll give you Chuck’s opinion—we don’t really have electronic medical record systems for documenting the care of the patient. What we have are electronic systems that capture information required for billing. That’s part of the problem. We have all these required elements clinicians have to document—physicians have to dot all the i’s and cross all the t’s—to get the appropriate words in so it can be translated into billing codes, ICD-10 codes, HPS codes, and so on. It truly gets in the way of taking care of patients.

But once we get that discrete data, we can use AI and other tools to help determine a better course of treatment. You’re never going to hear me say that we should depend solely upon AI. It has to be moderated and reviewed by someone with clinical training. Physicians have shown me I’ve been wrong more times than you can imagine. Working together and having good data aggregation is important.

One thing I learned early on when implementing the first physician order entry and clinical documentation systems was that physicians said: “Don’t tell me what I already know. Tell me what I don’t know. Better yet, tell me what I need to know about the patient in front of me right now.” There are things they don’t know. That’s where data aggregation from health information exchanges helps, because patients don’t get care in one location or from one physician.

I’m living proof of that. I get care in two—actually three—health systems because that’s where my specialists are. My primary care doctor wants to know what my orthopedist did or what my cardiologist’s course of treatment is, because he’s managing my diabetes and a few other things. Having access to information—recent labs, imaging studies—is extremely important.

We talked about interoperability, and that’s where it comes into play. Most hospitals in Indianapolis are on Epic, so you can get data easily. From non-Epic systems, there are mechanisms too. When I see my cardiologist—who uses a different system—and he already knows what my medications are because they were recently changed by another physician, that’s positive. I don’t have to list everything. When they know my latest labs, that’s positive too, because we’re not hunting for information.

It’s about providing information that is important to the treatment at that moment.

I had the privilege of sitting in a presentation—maybe eight or nine years ago—at Scripps Institute. They showed a demo of what a patient encounter could be. It was very Star Trek–like. The computer or AI interacted with the physician and patient appropriately. It listened in the background and captured information about the encounter. When the physician said, “We need to order a CT scan of your lower abdomen,” it was already getting that scheduled. When the patient was ready to leave, everything was set. It was also checking for recent labs and reminding the physician if the patient—say a diabetic—was due for an eye exam or foot check.

I think it’s about having access to the information so we can inform—not determine but inform—the physicians. Because at the end of the day, physicians are accountable for the outcomes. They have to be in control, not the AI.

Ritu: Yeah,

Charles: we’re not ready for Skynet yet.

Ritu: I think you described a multi-agent system where the agents are off doing things and then bringing it all back for the physician to review. With that being said, we all know that AgTech is one of the top trends everyone’s talking about these days. What are your thoughts on voice agents? Where is Franciscan with that? Have you had exposure to or tried voice agents in the hospital?

Charles: Yeah, we’ve got a trial. We’ve got over 200 physicians working on those. Is it going to be the end-all, be-all? I don’t know. The physicians seem to like it. It assists them; it helps with their pajama time.

I’ve listened to conversations from other health systems that were early adopters, and I have to go back in time to when we were looking at automating physician practices in Southern Indiana. We visited a group of 14 family practice doctors. The husband and wife who started the practice mostly did OB and family medicine. Their use of computers was minimal—they were still mostly on paper. But they had other physicians who, I think, slept with their laptops.

The interesting thing was that depending on how well a physician adopted the computer system and molded it to how they practiced, they got to take advantage of it. I think it’s going to be the same with AI and voice agents. If they allow it to help and figure out how to incorporate it into how they think and practice, they’ll see the benefit. The systems are pliable enough now that it’s easier to do.

When I was in Georgia, we needed to automate a lot of OB practices on the same platform. One OB had been practicing almost 30 years and already had a solution he had customized. He told me I would tear it out of his cold, dead fingers. So we worked with him. The new system was more flexible and pliable than his old one, and he became a champion because he was willing to take the time to understand how he could use the technology to help him practice.

I think that’s the key. If you’re resistant to it, that’s fine—that’s perfectly okay. But people who write software often think all physicians think the same way. They’re absolutely wrong. It depends on where they trained. I learned that when implementing emergency room electronic medical records. The physicians who helped design the software were trained with a very different approach to critical thinking than our physicians. We had to relearn and figure out ways to adjust, because once clinicians are trained a certain way, it’s hard to change those habits and the way they gather and maintain information.

Ritu: Thank you. Great answer.

Rohit: Chuck, I’d like to ask your thoughts about the innovation process. How do you approach it, and what are some of the things you do to foster innovation?

Charles: One of the things we did was stand up a Tech Innovation Lab. Honestly, it was a selfish move because people were just bringing technology into the organization. All the enterprise architects report to me, and we work together to understand what will work in our environment and what won’t. We try to standardize as much as we can.

So I created the Innovation Lab to bring these innovations into a controlled environment and try them there. It’s a walled garden. It’s not connected to the rest of the network. It has its own connections to the internet. So if we blow something up, it only blows up in the lab. That’s why we did it.

What we’re able to do is bring ideas in and fail fast—figure out what works and what doesn’t. We’ve done that several times. Virtual nursing is something we’ve worked on a lot. There were all kinds of interesting opportunities brought to us. One facility went ahead and put a solution into a live patient population, and we found out quickly that’s not how you do it. You don’t test that kind of thing in a live environment. It frustrates the staff and patients, and it leaves leadership thinking, “We already tried that—it doesn’t work.”

Well, you tried what doesn’t work. Let me show you what will work.

We needed the opportunity to rapidly figure out what would work. One issue with that failed experiment was that the people who built the carts didn’t understand our environment. They put a wireless access point in the cart that was incompatible with our network. Once we got the cart, we figured it out quickly. We re-engineered it, and it works fine now—but we’re not using that cart because it was over-engineered and very expensive.

We’re trying to use standard components that can be supported and replaced quickly. The idea is to generate a lot of ideas and figure out how to use them appropriately without getting in the way.

You also have to think about the aesthetics of the equipment you’re bringing in. The first cart had a big five-wheel base—kind of a star shape. In some patient rooms, it was in the way. Nursing quickly said, “That’s not going to work.”

So we found an iPad holder that hangs on the patient’s bedroom wall when not in use. It’s out of the way, easy to access, and uses magnetic connectors so if someone snags it, it just comes apart. No trip hazard.

You must consider not only the technology but how it fits in patient rooms.

Originally, the idea was that the Innovation Lab would review the technology, understand how it fits together, and then install it in our SIM labs. We have two—one north, one south. Then the simulation teams would put it in a physician office or patient room and see how it fits before we use it in live care. That’s our next step with virtual nursing.

We also have a lot of conversations with organizations that have fully rolled out these solutions. We learn from their experiences. A mistake is only a mistake if you don’t learn from it. If you do, then it’s experience. We leverage their experience so we don’t repeat the same things, and so we can move quicker.

Rohit: That’s awesome. As we are approaching the end of the podcast, I would like to ask if you would touch on the mentorship program.

Ritu: Yes, I would really like to hear more about that, Chuck, because it’s something unique and I think it would be interesting for our listeners as well.

Charles: Just making sure we’re talking about the virtual mentoring program. After COVID, we were bringing on a lot of new nurse graduates. When you bring someone into that role, they need a more experienced nurse for a procedure they may have never done before. That usually means waiting for that nurse to come to them.

We had a couple of nursing staff in the mentorship program who came up with a way to use technology for an on-screen virtual visit with the new nurse. The experienced nurse could walk them through the procedure and be there with them, or if the new nurse had a question, they could step out into the hall, ask it, and go back in. It improved speed to delivery of care more than anything else.

It also gave seasoned nurses a chance to step away from what they were doing instead of traveling to another location. If they need to go in person, they still do, but this gave us another option. We got great feedback from both the new nurses and our more mature nursing staff, and we rolled it out through the enterprise. I haven’t checked in on it recently, but I assume it’s still running. I only hear when things break, and if it’s not broken, I’m not going to fix it. I assume the technology is still working and paying dividends.

Ritu: Thank you so much.

Rohit: So, Chuck, as we come to the end of the podcast, any closing remarks or thoughts you’d like to share before we finish?

Charles: I’ve been in healthcare a long time. Healthcare is a target rich environment for creativity and innovation. But we’re still taking care of patients the same way we did, and it’s about the human touch and caring for people.

When I first started in radiology years ago, I was taken aback that people weren’t always treated as people. They were exams. Do this gallbladder in this room, do this hip nailing in that room. I was reminded they’re people. They could be my family. They could be my children. That’s why I’m passionate about making sure the technology works and doesn’t get in the way.

Have we reached the pinnacle? No. Is it better? I think it is. But we’re still trying to figure it out every day. As long as we have great people passionate about providing outstanding care and we understand where that ability comes from, we’ll keep moving forward.

We’re a Catholic healthcare system, and our rule is we start most meetings with prayer. We are called to love one another as God loves us, and we need to remember that every day. That’s why I keep doing what I’m doing.

Rohit: Awesome.

Ritu: Thank you so much, Chuck.

Rohit: Really appreciate it.

Charles: Okay. Thanks for the opportunity to share.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

How to Build AI Literacy Programs in Healthcare Organizations

How to Build AI Literacy Programs in Healthcare Organizations

As artificial intelligence (AI) reshapes every industry, healthcare stands at a critical inflection point. Generative AI, predictive analytics, and intelligent automation are changing how clinicians diagnose, treat, and manage patients. Yet the biggest challenge isn’t technology – it’s people.

AI literacy has become essential to bridging the gap between innovation and real-world healthcare impact. It involves equipping professionals to understand, evaluate, and responsibly collaborate with AI systems. Without it, even the most advanced tools risk underuse, mistrust, or outright rejection. Building AI literacy goes beyond learning how to use new technologies, it’s about preparing the healthcare workforce to partner effectively with AI, interpret its outputs, and make informed, ethical decisions in patient care.

In one of the recent episode of The Big Unlock podcast, Jan Beger, Head of AI Advocacy at GE HealthCare joined hosts Rohit Mahajan, Managing Partner and CEO at BigRio and Damo, and Ritu M. Uberoy, Managing Partner at BigRio and Damo to share insights from GE’s global experience in building large-scale AI literacy programs. His perspective offers a practical roadmap for health systems, medtech firms, and digital health leaders who are navigating this transformation.

Why AI Literacy is the Cornerstone of AI Adoption

AI literacy sits at the intersection of technology, people, and culture. As Jan notes, healthcare conversations about AI often “get technical very quickly,” leaving behind the clinicians and professionals expected to use these tools in their daily work.

To make AI adoption sustainable, organizations must focus on the human side of innovation – helping staff understand what AI can and can’t do, building trust in its outputs, and empowering people to see it as an enabler rather than a threat.

According to a study by Workday and LinkedIn, 70% of job skills are expected to change by 2030, with AI driving much of that shift. In healthcare, where regulation, risk, and ethical complexity are high, this means rethinking skill sets and workflows in real time.

AI literacy ensures that clinicians, administrators, and executives can use AI responsibly to improve patient outcomes and system efficiency.


Defining AI Literacy for Healthcare

Jan Beger offers a simple but powerful definition of AI literacy built around three competencies:

  1. Collaborate responsibly with AI: Understand the fundamentals of AI, from machine learning to generative models, and how they integrate into clinical or operational workflows.

  2. Explain AI outputs: Be able to interpret what the AI system is showing — for example, how an algorithm supports a diagnostic decision or a chatbot retrieves information.

  3. Critically evaluate AI outputs: Avoid blind trust. Clinicians and employees must question results, verify data sources, and know when human judgment should override machine recommendations.

This mindset shift, from passive use to active collaboration, is the foundation of effective AI literacy.


Designing a Scalable AI Literacy Program

GE HealthCare’s approach provides a template for others to follow. Their Responsible AI strategy integrates literacy into employee education through multiple channels:

Live sessions and workshops with AI experts for hands-on learning.

Best-practice sharing sessions where teams demonstrate how they’ve applied AI in real workflows.

Self-paced learning modules tailored for different roles and levels of expertise, from basic AI terminology to deep dives into specific use cases.

For example, GE’s Hello AI program offers foundational and professional courses for healthcare professionals and students. The free foundational module introduces key AI concepts, while the professional course provides 25 hours of specialized healthcare content for a nominal fee. Over 5,000 healthcare professionals from 70+ countries have already participated.

This layered, accessible model helps organizations with large, distributed workforces like GE’s 51,000 employees across 160 countries — develop AI fluency at scale.


Building Engagement and Overcoming Resistance

Change management is at the heart of any AI literacy initiative. As Ritu M. Uberoy, co-host of The Big Unlock, noted, healthcare professionals often approach AI defensively: “Why should I do something that’s going to take my job away?”

To address this, organizations must position AI as a tool for empowerment, not replacement. Jan emphasizes that in every conversation, “we need to remove worries and fears among healthcare professionals” and show how AI helps them do their jobs better by increasing accuracy, efficiency, and patient satisfaction.

Face-to-face engagement remains key. Jan, who travels extensively to meet clinicians and hospital teams, finds that in-person discussions build trust and reveal practical barriers that online training alone can’t address. However, hybrid approaches which is a combination of digital learning and local advocacy can make programs more sustainable and scalable.


Measuring Success and Evolving Continuously

No literacy initiative is complete without metrics. Organizations must define what success looks like, and it will differ by role.

For example, GE HealthCare measures tangible productivity gains among software developers using AI coding tools. But for field engineers or clinical teams, success may initially focus on engagement, confidence, or adoption rates rather than speed or output.

As use cases evolve, KPIs must evolve too – from tracking participation in AI courses to measuring how AI literacy translates into improved workflows, reduced errors, or better patient outcomes.

Another lesson from GE’s experience is – AI literacy programs are not “set it and forget it” initiatives. They require continuous updates, new content, and maintenance to reflect the pace of innovation and regulatory changes.


The Broader Mission: Rethinking Roles in an AI-Driven Future

AI literacy isn’t just an education program, it’s a mindset shift. As Beger summarizes, everyone in healthcare should “start rethinking their job descriptions with AI in mind.” Understanding how AI can augment one’s role fosters curiosity, confidence, and innovation.

Moreover, Jan’s call to action extends beyond healthcare: “We have so many great AI experts working in gaming or banking. If they truly want to make an impact on society, they should consider joining healthcare.” That spirit of collaboration across domains, between technologists, clinicians, and educators, is what will truly accelerate the responsible use of AI in healthcare.

Building AI literacy programs in healthcare is not a technical challenge, it’s a leadership one. It requires empathy, structure, and a relentless focus on people. GE HealthCare’s example shows that when organizations invest in education, trust, and responsible innovation, they don’t just prepare their workforce for the future, they help shape it.

Empowering Patients and Closing Health Gaps with AI and Connected Care

Season 6: Episode #186

Podcast with Anil Saldanha
Chief Innovation Officer
Rush University System for Health

Empowering Patients and Closing Health Gaps with AI and Connected Care

To receive regular updates 

In this episode, Anil Saldanha, Chief Innovation Officer at Rush University System for Health shares how Rush is addressing deep-rooted health inequities in Chicago by targeting the life expectancy gap through bold, system-wide interventions.

Anil highlights Rush’s commitment to public health, chronic disease management, and early cancer detection by referring to innovative initiatives like Rush Connect Plus, which is an on-demand, subscription-based virtual care model, and the rollout of Grail’s multi-cancer early detection test. He explains their use of cutting-edge AI technologies, from ambient listening and AI-powered symptom checkers to novel behavioral health kiosks leveraging multi-agent generative AI for PTSD care.

Anil points to the impact of consumer-driven digital tools, health equity analytics, and a data warehouse that will enable targeted interventions for chronic care. He closes with optimism about AI’s future in healthcare, the shift toward “connected care anywhere,” and the growing role of empowered, informed patients. Take a listen.

Video Podcast and Extracts

About Our Guest

Anil Saldanha is the Chief Innovation Officer at Rush University System for Health. With a background in business and technology, Anil has the advantage of having learned skills and experiences in non-healthcare fields to now transform healthcare at Rush. He operates at the intersection of public health, community health, and delivery. He was a founding team member of Tempus AI in Chicago and has held leadership roles at companies such as GoSecure Inc., Trustwave Inc., Red Hat Inc., and Sun Microsystems. He is a strategic advisor on innovation and transformation to clinical, research, and technology leadership at Rush.


Ritu: Hi Jan, welcome to our podcast. We are so happy to have you here on The Big Unlock podcast, season six, and we are headed to 180 plus episodes now. Really great having you on the show today. Just a brief introduction — my name is Ritu Roy. I am the Managing Partner here at BigRio and Damo Consulting and a co-host of The Big Unlock podcast with Rohit. And with that, I’ll hand it over to Rohit. He can give a brief introduction and then over to Jan. Thank you.

Rohit: Hi Jan, great to have you here, like Ritu said, and thank you for making the time in the evening from where you are in Germany. Really excited to have this conversation. I’m Rohit Mahajan, CEO and Managing Partner at BigRio and Damo Consulting. And with that, Jan, would you like to start with your intro?

Jan: Absolutely. First of all, thank you both for having me today and for the invitation. Truly appreciate it and looking forward to a good conversation about this exciting topic of artificial intelligence in healthcare. As you mentioned, my name is Jan Beger, Head of AI Advocacy at GE Healthcare. My mission is to transform AI in healthcare from a conceptual promise into a high-impact reality. I focus on equipping healthcare professionals, executives, and the next generation—like students—with the knowledge, skills, and mindset to thrive in this AI-enabled future of healthcare.

Ritu: That’s really great. Wonderful introduction and really interesting title you have, Jan, because we’ve talked to CIOs and CMIOs, but you’re someone who’s the Head of AI Advocacy. I think that’s something new. Would love to hear about your journey—how you came to be in this role, how you combine expertise in healthcare and AI, and what your vision for AI is at GE Healthcare.

Jan: Thank you so much. I hope you agree—based on the many conversations you’ve had in this space with different experts—when we talk about AI in healthcare, those conversations very quickly get technical. But I think in healthcare, and maybe as an entire industry, we have not focused enough on one important aspect: making sure that those clinicians and healthcare professionals we expect to use AI technologies are taken with us on this technology journey.

So, things like change management and education—making sure we focus on the human aspect—is something I think has not been emphasized enough across the industry, maybe even to a point that it slows down AI adoption. This is what I’m really focusing on—what we need to do to remove worries and fears among healthcare professionals, help them gain a solid understanding of the technology, build basic trust in AI, and get them interested in testing and piloting these solutions. Ultimately, the idea is this could lead to faster adoption.

Ritu: Yeah, that’s an extremely valid point, Jan, because I was just at a conference at MIT yesterday, and this was one of the key things that came up — that it can’t be a top-down approach because whenever you ask somebody to do something, their initial reaction is to go into defensive mode and say, “Why should I do something that’s going to take my job away?” or “What’s in it for me?”
So we would be really interested in hearing from you how you are able to get buy-in from the teams across GE and get everybody on board, making sure everyone has the literacy skills, like you said, to understand that AI can actually be a tool to do your job better, increase productivity, bring efficiency, and do all the good things AI promises.

Jan: First of all, I think across different domains and industries — in a health system, but the same in a medtech or healthtech company — everything is being reinvented right now in real time. There’s a lot of activity in that space.
We at GE also look into processes and how we can support our workforce with generative AI technologies. Again, the technology is one part of the story; the second is how we make sure we enable our workforce — 51,000 employees across the globe in 160 countries — to leverage this technology well and responsibly, to truly make a difference in their day-to-day work.

This is exactly the same in the healthcare space as well. We are entering a state of skill redefinition in real time. Things that were important in the past — like routine execution, static expertise, or hierarchical knowledge — are becoming less relevant. And on the flip side, we see more important skills emerging, like adaptability, systems thinking, tech fluency, and AI know-how.

We all have to prepare for this. There was a study recently done by Workday and LinkedIn, which said that 70% of job skills are expected to change by 2030, with AI driving much of this shift. This is not just healthcare — this is across different industries.
Maybe in healthcare, this kind of change will feel a little bit slower because it’s highly regulated. But what I want to say by mentioning this number is that there is a massive technology transformation ahead of us, and a lot of people don’t even understand that this is coming — and coming with quite some impact.

We not only need to continue building great technologies and integrating AI into products and workflows, but also need to create awareness and build AI literacy so that everyone across the healthcare ecosystem can use this technology responsibly for better care and improved patient outcomes.

Ritu: Thank you, Jan. That answer leads into two follow-up questions. First, like you said, the speed of invention is at an unprecedented scale, which we haven’t seen before. The speed is also leading to democratization, where anybody can do low-code or build a tool or a prototype.
That leads to the next thing — this whole concept of AI literacy. If the tools are so easy to use and can unlock so many new ideas, you want everybody across the company to understand how to use them and be fluent. So, how does GE, with such a large employee base — 51,000 employees across 161 countries — handle this? Do you have an overall AI literacy program with different levels, or what systems are you setting up to address this?

Jan: Great question. First, I should define what AI literacy means to me, because it could mean different things for different people.
In a nutshell, I would say it’s three things: one is the competencies required to collaborate responsibly with AI and interact with technologies such as large language models and generative AI.
The second is to be able to explain their outputs.
Third, it’s to be able to critically evaluate those outputs — and then do something meaningful with them. As you know, the worst thing would be to blindly trust those outputs and leverage them in your day-to-day work. So, critical evaluation is a very important part of AI literacy overall.

At GE Healthcare, there is an AI literacy program in place, which is part of a broader Responsible AI strategy. We have different ways to educate our teams — live sessions where they can dial in and learn from experts on how to use generative AI integrated into our tech stack, best practice sharing sessions, and self-paced learning offerings for employees at different levels — from a foundational course covering basic AI terminology to more use-case-specific, in-depth training for specific groups and roles.

Rohit: I was just wondering, Jan, about the key initiatives you’re taking, which are so valuable moving forward for the company and the employees themselves, because they’re basically increasing their skillset as well. We’ve been thinking about some success metrics for our own organization and for some of our clients who’ve been asking for similar services. Any thoughts or ideas, Jan, on what success metrics one could track for such initiatives in any organization setting out on this journey?

Jan: I think those success metrics and KPIs are critically important to measure traction and see where we’re heading and if the investment in these efforts makes sense. For instance, one area where we’ve seen early positive results is with our software developers. With AI capabilities, we’ve seen improvements in speed—getting code done, getting code reviewed, those kinds of things.
So this is maybe one area where, across industries, we already have several best practices and standard ways to measure performance and progress. But then there are other groups of employees where those measures are harder to obtain, or maybe it’s too early because we just started using these capabilities.

For instance, our field engineers—people who visit customer sites to check or repair MRI devices—now get AI support through tools we’ve developed where they can have a natural language conversation with the service manual of a specific device or get help with scheduling. Those are new use cases, and we’re still defining the right success measures or KPIs for them.
There’s a wide range of capabilities and use cases across different groups and business units. Over time, we’re getting better at measuring progress. As I mentioned, in software development we already have specific measures in place and are seeing the benefits of AI, but there are other areas where it’s still greenfield, and KPIs will evolve over time.

Ritu: Thank you, Jan. Our listeners—and most of us—always like to hear about success stories and success metrics, but it’s also important to learn from failure. It would be really interesting to hear from you about a couple of cases where things didn’t go so well, what you learned from that, and how you came back to do something even better.

Jan: I’ll give you an example of a tool we built in-house to support our marketing teams with approved external communication content. We’re feeding a retrieval-augmented generation model with external content so that when a communications specialist gets a request from the media, they don’t need to start from scratch—they can leverage this chatbot, get approved responses, tweak and refine them, and then use them.
It’s useful, but it’s also a lot of work—making sure the knowledge base of the chatbot is always up to date. Maintenance is a challenge and requires manpower and effort. So it’s not just a one-off where you build a cool AI tool and send it out for people to use. A lot of those tools require continuous focus, effort, and maintenance.

Rohit: While you do this at such a global scale, are you traveling a lot and meeting people in person to motivate them, or are you using online tools to make this happen? What are some of the key tools or methods you’re using for the advocacy you’re doing with such a large group of people?

Jan: That’s a great question. When I introduced myself, I should have mentioned that I focus most of my time on our customers—health systems, hospitals, and healthcare professionals—and focus my AI advocacy and literacy work mainly on clinicians.
To answer your question, I travel about 80% of my time. I’ll be in the US next week in Seattle and Atlanta. It’s important to meet medical and clinical experts in person. I always learn from them—I want to understand their concerns, fears, issues, what works, and what doesn’t. Even with great remote technology, face-to-face works best for me.

Of course, there are things that can be done online too. For example, for a few years we’ve been running an AI literacy program for healthcare professionals called Hello AI. When you go to helloai-professional.com, you’ll find more information. It’s a self-paced e-learning offering with two modules where clinicians, students, researchers, and executives can educate themselves about AI in healthcare.

We’ve received great feedback. So far, we’ve educated more than 5,000 healthcare professionals from over 70 countries. Later this year, we’re launching a new learning module built specifically for healthcare executives—because this population is becoming increasingly important in the overall transformation.
Over the last few years, healthcare systems have made progress adopting and piloting AI, but mostly through point solutions—like a decision-support tool in radiology or something with EHRs. Executives now need to think about AI strategically—how to plan, deploy, and measure ROI at a system level. That’s why we’re launching this new offering for healthcare executives on the Hello AI platform later this year.

Rohit: That is fantastic. I think there’s definitely a need for such a thing. Tell us a little more about Hello AI. How did it come into being? Did it precede your joining GE Healthcare, or is it a GE Healthcare initiative? We’d love to learn more about this venture.

Jan: Thank you so much. First of all, when we think about AI in healthcare, there’s often the impression that this is a domain led by big tech or the innovative healthcare AI startup ecosystem around the globe. But that’s only partially true. The reality is that when you look into AI and machine-learning-enabled medical devices, you’ll quickly realize that it’s also a huge play for traditional medtech.
Companies such as GE Healthcare and Siemens Healthineers are leading the pack. The FDA has authorized more than 1,000 AI-enabled medical devices so far, and about 100 of those come from GE Healthcare.

We feel a responsibility as a leader in this field not only to build and integrate great technologies into our devices but also to focus on the change management and education for those we expect to use these technologies. This is how it started—and what Hello AI is.

It’s a learning offering for healthcare professionals and executives built by a network of partners—GE Healthcare, universities, and technology companies—working together to spread the word. Our mission is to make AI literacy accessible and affordable for healthcare professionals worldwide.

We’re trying to provide healthcare AI–specific education, not just general AI education. There’s a lot of free AI content online from big tech, but we focus on healthcare-specific AI education at no or low cost. For instance, we currently have two modules: a free foundational course for everyone, and a more in-depth Professional course with 25 hours of content for just $99.

Rohit: That’s awesome. Would you be open to licensing this as well? In case a large enterprise is interested in your offerings, I’m sure you’re looking at some licensing deals too.

Jan: Our partnership model is threefold. First, we look for partner institutions to join Hello AI and co-develop new content. AI is a fast-paced field, and there’s a lot happening. For instance, earlier today we had a session on federated learning, which is part of new content we’re adding to our modules.
Second, we focus on co-marketing and co-promotion.
Third, when an institution joins us and contributes in these areas, we provide their employees or members free access to Hello AI content.

Rohit: That’s awesome. This is great—you’re offering such a robust platform to increase awareness and education in this space. As we come to the end of the podcast, Jan, any other thoughts or predictions in AI? There’s a lot of agentic AI coming our way—any thoughts for the future audience?

Ritu: And I think Jan wanted to show the device, which might relate to my question: do you have an example where AI has made a difference in patient outcomes—something you’ve put into a device that really made an impact?

Jan: Maybe just quickly, Rohit. I’ll share a use case that’s been very impactful, and then I’ll give a few takeaways. First, as I showed earlier, this is a handheld wireless ultrasound scanner for specific use cases. Imagine an emergency doctor carrying this wherever they go—a powerful imaging tool with no radiation. But one limitation is that it’s very operator-dependent. You need a certain level of education and experience to get high-quality medical images.

So a few years ago, we embedded AI into these machines. It tells you, while scanning the patient, how to move the probe to get high-quality images. This means even less-experienced clinicians can achieve excellent results. The idea is to democratize ultrasound so it’s accessible to more users. That’s just one of many examples of AI making an impact in healthcare today.

A few takeaways for your audience:
First, I strongly recommend everyone—whether in tech, corporate, or healthcare—start rethinking their job descriptions with AI in mind. Think about what you do every day, how AI could support you, and how it changes your role. When you start thinking this way, you’ll begin learning about AI, open your mind to opportunities, and adopt the right mindset to embrace this technology.

Second, we have so many great AI experts, data scientists, and developers worldwide working in industries like gaming or banking. If you know them, tell them about healthcare. If they truly want to make an impact on society, they should consider joining healthcare. It’s still early-stage and slower because of regulation, but if you have this expertise, the industry would truly value it. We can make a real difference here.

Ritu: Thank you, Jan. This was awesome. I’m sure listeners have a lot to absorb and reflect on. Your call to action is excellent—this is an industry where we can see the maximum impact and really help people. Thank you.

Jan: Thank you so much for inviting me.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Day 4 – Driving Action from Innovation

Day 4 – Driving Action from Innovation

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Rohit Mahajan

Co-Host of The Big Unlock Podcast

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Wrapping up Day 4 at HLTH USA 2025, the energy of this event remains strong—and with good reason. The conversations here long ago moved beyond ideas to tangible actions shaping the future of healthcare.

Today’s sessions and keynotes emphasized sustainable, equitable healthcare models anchored in AI and data-driven insights. What stood out most to me? The recognition that technology’s true value lies in how it delivers measurable impact—improving care access, outcomes, and provider workflows at scale.

The main stage brought leaders together around one common goal: aligning innovation with real-world healthcare challenges. From diagnostics to policy, from startups to enterprises, the message was clear—collaboration is essential to accelerate progress.

I was particularly inspired by the final partner meetings and exhibitor demos that spotlighted solutions ready for deployment today. This event has reinforced why HLTH remains the go-to platform for driving healthcare transformation forward.

As I reflect on these past days, I’m excited to continue uncovering and sharing stories that unlock the next chapter of health innovation through The Big Unlock Podcast.

Thank you to all the brilliant minds who made this year’s HLTH so impactful. Until next time—let’s keep turning breakthrough ideas into better health outcomes.

#HLTH25 #HealthcareInnovation #AI #HealthEquity #TheBigUnlock #DigitalHealth #RohitMahajan

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Advancing Pediatric Care with AI in Radiology and Virtual Trials

Season 6: Episode #185

Podcast with Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital

Advancing Pediatric Care with AI in Radiology and Virtual Trials

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In this episode, Dr. Paul Yi, Associate Member, Department of Radiology, Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children’s Research Hospital, shares his journey from radiology training at Johns Hopkins to leading AI initiatives at St. Jude, focusing on pediatric cancer and other catastrophic diseases. 

Dr. Yi highlights how AI is transforming the radiology workflow, from automating imaging protocols and improving image reconstruction to translating complex medical reports into patient-friendly language. He emphasizes the importance of data strategy, discussing the integration of clinical EMRs, PACS, and research databases, ensuring interoperability while leveraging domain expertise across disciplines. He explores generative AI applications, including virtual imaging trials that simulate patient populations for safer, faster, and cost-effective clinical research, as well as patient-facing applications like AI chatbots for healthcare education, noting both potential and limitations in trust and accuracy.

Dr. Yi reflects on bridging research and commercialization, underscoring the need to align academic and industry incentives. He envisions a future powered by multimodal AI models that combine imaging, vitals, labs, and clinical text to deliver comprehensive, personalized insights – accelerating precision care and innovation in pediatric oncology. Take a listen.

Video Podcast and Extracts

About Our Guest

Paul Yi, MD is an Associate Member, Department of Radiology and Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children's Research Hospital. Dr. Yi is a practitioner of diagnostic imaging. The field of radiology and diagnostic imaging has been a proving ground for medical applications of artificial intelligence for a number of years. As a physician-scientist, Dr. Yi’s research interests include the development and application of AI and deep learning towards medical imaging applications, with special interest in evaluating the trustworthiness and fairness of deep learning models.


Q: Hi, Dr. Michael Docktor, welcome to our Big Unlock podcast. We are really happy to have you as a guest on our show. Uh, it’s on our sixth season now, and, uh, we are looking forward to this conversation. I’m sure we’ll have a very engaging and interesting conversation about dog health, about healthcare in general, and the new trends about AI and all the buzzwords that people want to hear. Welcome to our show — we’d like to start with introductions. Happy to have you give your introduction. Thank you.

Michael: Yeah, thank you so much for having me. Yeah, I’m Michael Docktor, co-founder and CEO of Dock Health. I’m an ologist by trade. I am now on this, uh, healthcare venture outside of Boston Children’s Hospital where I started my GI career.

I was a busy clinician working on the clinical side as well as in innovation and informatics, and found that we had wonderful tools in the world outside of healthcare and struggled with my own challenges around managing all the tasks that are part of patient care. I found that I was using task management and project management tools that were not built for healthcare.

I scratched my head and wondered why we don’t have these things for healthcare. That was a journey. We started just over five years ago. We spun out Dock Health from Boston Children’s, and we’ve been on a very exciting journey in the world outside the academic walls since then.

It’s been fun. I’m excited to talk to you more about, uh, what we’re doing.

Q Great. That’s a great introduction. Thank you for letting our listeners know. We usually like to start with how you came into healthcare because everyone has an interesting story about what inspired them to become a physician.

For you, it’s particularly interesting because you’ve created this interface between design, technology, and healthcare — and you went beyond just visualizing what you wanted to do or asking why somebody doesn’t fix it, to actually building it yourself. I’d love to hear more about how you came into medicine and then into technology.

Michael: I could probably spend the entire podcast on this question. Obviously, my last name is Doctor, so there was some planting occurring there, and there’s something to be said for that.

One of my earliest memories was wanting to grow up to be a doctor. My younger sister had some GI issues when we were young, and I became very close with her gastroenterologist. I followed her on her journey and, unbeknownst to me, ended up following one of my mentors and was inspired to do the work for other children the way my sister was cared for. That was the initial inspiration.

You mentioned design. That’s interesting because my mother is an interior designer, my father is a dentist who specialized in aesthetics, and design — how things look, feel, and work — has always been part of my DNA. It was an amazing journey to go from being a traditional doctor in pediatric gastroenterology to discovering the importance of user experience and user interface.

Then the iPhone came out, then the iPad, and that really started me on my journey of exploring app development and software, and wondering why we didn’t use these wonderful devices in our pockets the way we should. That journey started more than 10 years ago and has led me to this perfect intersection of healthcare, design, and informatics, creating better experiences for patients and providers.

There’s a lot to unpack there, but people ask me if I would do it differently if I had the chance to do it all over — and absolutely not. I’m doing exactly what I want to be doing right now.

Q: Thank you for sharing that. That gives us so much perspective into how you came into this field, the influence of your parents, and how everyone around you inspired you to do this. That’s really interesting.

That leads us into how you built Dock Health. Tell us some examples of how you saw this becoming transformational in actual implementations with clients. When you built the tool, did you visualize exactly what it would do? Did it go beyond what you thought it would achieve in a healthcare setting? We’d love to hear more about that.

Michael: We’re far beyond where I ever thought we’d be when we first started this journey. That’s the exciting part. Fundamentally, we have such an administrative and operational challenge in healthcare. I saw it firsthand as a busy clinician struggling to manage all the clinically adjacent work that had to be done for my patients.

For example, I might have a patient with Crohn’s disease who needs to go to an infusion center. There are all these downstream tasks and administrative steps that need to be done by a team of people. We didn’t have assistants to do that, and the electronic health record wasn’t built for it.

A quarter of the $5 trillion spent in healthcare goes to administrative and operational challenges, and there really are no tools built for that. We rely on paper checklists, email, faxes, and spreadsheets to manage all the work happening outside the electronic health record.

For me, the realization was that I was using wonderful project management and task management tools to run software projects in my innovation and informatics roles—and yet nothing like that existed in healthcare. Patients, in many ways, are projects. There are tasks that form the essence of care, and they need to be tackled, managed, and collaborated on, with visibility and accountability across teams. That didn’t exist.

What we are now doing is serving as that productivity platform for healthcare, one that sits alongside the electronic health record in synergy, helping manage all the administrative and operational tasks of patient care in ways the EHR wasn’t designed for.

Some examples would be managing patient intake and all the processes associated with it. Referrals, inbound and outbound, with all the paperwork, eligibility checks, and faxes—those workflows are still incredibly manual. Referrals are a great example: 80% of referrals that come into major academic medical centers are still arriving by fax, despite the fact that they’re using Epic, a wonderful electronic health record.

These processes are still incredibly laborious, take too long, and are inefficient. Patient care suffers along the way. There’s a gigantic bottleneck around the administrative and operational work that moves patients through their journeys, and that’s what we’re focused on fixing.

Q: This is what we hear from a lot of our clients and other CIOs and C-suite leaders who come to our podcast—that this is one major problem with healthcare. It’s siloed, and the processes are really stuck in the dark ages.

We were talking to somebody from Athena, and they said they had an 800-person offshore center in India just to screen faxes. When a fax came in, one person looked at it to see if it was a pizza order or a referral. It sounds unbelievable in this day and age, but that’s how it works. I’m amazed to hear this from you as well. It’s remarkable.

Michael: Yeah. In fact, Athena is a partner of ours, and we’re working on referral management. It’s an incredibly antiquated process where everyone loses visibility. The amount of manual labor required to process these things is shocking in this day and age, when they can be handled through process automation, AI, and agents.

Q: Exactly. You’re talking about agentic, we’re talking about voice agents, and yet we’re still dealing with faxes. That’s really interesting to know.

Michael: There is reason to be hopeful. Healthcare is always many decades behind, but the adoption of AI is progressing more rapidly than I’ve seen any technology adopted in healthcare. There’s reason for hope.

Q: That leads into my next question, but before we get there, you mentioned Dock Health as a productivity platform. That’s what it does for doctors, clinicians, and patients. But when we talk to our doctors, clients, and health systems, the one word that always comes up is complexity. They deal with so many different systems and have to learn something new each time.

Where does Dock Health fit in? Is it another system they have to manage, or does it help reduce that burden?

Michael: Yeah, it’s all about reducing the burden and improving the user experience. That’s been fundamental to our belief system since the founding of the company.

First and foremost, we’re trying to become the productivity platform and the hub that handles the administrative and operational work. Instead of being “another system,” we’re often replacing spreadsheets, paper checklists, emails, and faxes—the ways we’ve traditionally managed the 50% or more of administrative and operational tasks required for patient care.

The EHR is great for clinical work, billing, prescribing, and scheduling, but so much happens downstream that isn’t covered. I’d argue we are creating the hub for that. Just as the EHR is the clinical hub, Dock Health serves as the operational hub. Together, it’s really one plus one equals three.

We’re also aiming to be much more consumer-like in our approach. Our tool can onboard a customer in 30 minutes. We offer a free trial, and for small organizations that want to get up and running, they can start using it right away—just like downloading an app. It’s lightweight, highly configurable for end users, and designed with a strong focus on user experience.

The real challenge is that clinicians don’t want another tool. They’re busy and need to spend their time in the EHR. Our core users are often the super users: front office staff, back office teams, operational leaders, and administrative staff who leverage our tool every day.

The important piece is that we connect to the electronic health record and provide visibility for clinicians. If they’re interested, they can see where a patient is in their journey or where a process stands, but they don’t have to be in our system all day, checking tasks or learning another workflow.

The intent is to provide that operational hub for administrative and support staff—the essential members of the care team—while clinicians continue their work in the EHR and often drive tasks into our system through their orders and actions there.

Q: Is the integration with the EHRs native, like with Epic, Cerner, and the big ones?

Michael: Yeah. We’re on the marketplace with a number of the top EHRs, including Epic and Cerner. We’re also working with Mayo Clinic, their Mayo Clinic Platform, and their Deploy platform.

The other thing I’d mention is that many organizations use our tools without being integrated with the electronic health record. That’s often because they’re smaller practices—mental health, concierge care, or primary care—that simply need a hub to handle administrative and operational work and collaborate as a team.

We spend a lot of time helping organizations define their processes, and those processes can then live in Dock, where they can be collaborated on and turned into operational best practices. That’s something that often doesn’t happen in traditional healthcare organizations, and our tool is valuable even when it’s not connected to an EHR.

Of course, the real value comes when we integrate with systems—EHRs, CRMs, patient engagement tools—and serve as the hub while automating as many tasks as possible. That’s when the flywheel starts turning, and organizations begin to feel the benefits of automation and work reduction. It ultimately moves the needle in a measurable way.

Q: So, you’re saying if there’s an integration with the EHR, then it’s end-to-end and people can see a complete view of what’s happening. But even without the EHR, because it helps with workflow management, it’s valuable for practices?

Michael: It’s just like every other industry. They have Asana, JIRA, Trello—all these tools where a lot of the real work gets done. That provides value in itself by giving a clear view into where the patient is in their journey and what process they’re following.

When we integrate with an EHR or other systems, we can then automate those workflows. For example, when a fax comes in, we can launch a workflow for a new patient referral. When a lab order is placed, we can launch a workflow for follow-up. Or when a patient has a procedure, we can launch a process for their downstream follow-up.

Q: That leads into the next question, which is your learning journey with AI. What advice do you have for our listeners about where AI is headed? And with voice agents and agentic tech being buzzwords, where do you see Dock Health going? Are you also looking at implementing voice agents?

Michael: AI is incredibly exciting. I’ve put it out there that we’re an AI-first company. We’ve been thinking about this for a while, and we already have what we call Dock Intelligence in production with customers. We started with the basics, using foundational models and generative AI to process large troves of data.

Now, we can summarize all the work being done for a patient and create a snapshot for the end user—showing all tasks, workflows, patient context, and even clinical context if available. That gives a quick overview of what’s happening. Users can edit that snapshot if needed, or generate a note that writes back to the EHR to keep the operational and clinical record in sync.

That’s the first step in our AI journey. From there, we realized tasks bundle into workflows, workflows can be automated, and now we’re starting to farm out those tasks to agents and AI. For example, a voice agent could follow up with a patient to confirm a referral or review lab results. We’re actively pursuing that, as well as leveraging AI to extract data from faxes to automate referral processes.

AI is the big unlock. In the next three to five years, I believe most administrative and operational tasks will be handled by automation and AI agents orchestrating together. These agents need rails to run on and structure to guide them, and end users must remain in the loop to provide oversight and visibility. But the lion’s share of this work will be handled by agents—and we’re building that future right now.

Q: Are you aligning specifically with any particular LLM or provider, or are you going to be completely agnostic?

Michael: I’d like to think we’ll be agnostic. We’re doing plenty of building on some of the foundational models ourselves, and we’re partnering where we can with great tools. For example, with voice agents, we’re not necessarily building them ourselves—there are excellent options out there. What we are doing is building our own homegrown AI agents that can manage processes and facilitate handoffs from task to task.

Our approach has always been to recognize that there’s a wonderful ecosystem out there. We want to be the hub that connects to the best-of-breed systems—whether that’s Epic as an EHR, Salesforce as a CRM, or other tools we can leverage to create a healthy ecosystem. That’s what we’re pursuing.

Q: I wanted to ask a question about that because with the LLMs, one of the main problems is the hallucinations or the repeatability or the trust factor there. So I saw that Dock is HITRUST certified. So, I just wanted to ask, what are your views on that? Because in terms of using generative AI when we talk to our clients, uh, for implementations on LLMs, or they’re more comfortable certainly with the administrative tasks, but even with the administrative tasks there’s always the question of what are the guardrails you put around that and how do you make sure that the results that you are seeing or you are displaying on Doc Health, you know, stay within that, those bounds of accuracy. Whathat are your thoughts around that?

Michael: AI is incredibly exciting—it’s moving at the speed of light, and everyone wants to benefit from it. I do think administrative and operational areas of healthcare are lower-hanging fruit and far less risky. We’re not yet in a place where we can reliably use AI for absolute clinical decision support and autonomy, though I believe we’ll get there in the not-too-distant future.

For now, the clunky and manual administrative work is ripe for AI. Still, we need to be mindful of potential hallucinations. In our experience so far, we haven’t seen issues, but we’ve put safeguards in place. That means keeping a human in the loop to ensure outputs are appropriate and relevant. We also give users the ability to edit results before they’re sent—whether it’s a summary being emailed to a colleague or written back into the EHR as a clinical note.

It’s essential to show your work. If we’re pulling data from various sources, we show those sources. We keep users in the loop, give them control to review and edit, and maintain tight feedback loops to catch and address anything off.

So far, even foundational LLMs have been surprisingly strong in our relatively narrow use cases. The real challenges will come as we move toward higher-risk clinical decision support—but I’m confident we’ll get there quickly.

Q: It’s interesting you mentioned humans in the loop and the fact that people can review or edit what’s being generated. But with agents, one of the key defining characteristics is autonomy—they can make API calls, send emails, even browse the web to find and act on information. How do you think about that level of control being handed over?

Michael: I think it’s all about balance. The value of task automation and workflow automation is clear. For us, one of our strengths is providing a user interface where the end user can actually see where a process is in its journey.

We’re working on features like showing confidence levels or confidence intervals for data extracted—for example, from a fax. That way, we not only show our work but also give transparency into how accurate that extraction might be. Using our interface, which breaks workflows into tasks, we can show exactly where a process stands. If we believe human involvement is needed, we assign a task and call someone in to review.

Even in the agentic future—which is already upon us and actively being built and tested—we see ways to keep humans in the loop. Operating entirely in a vacuum is risky. Part of my mantra, coming from clinical practice, is that I lacked visibility and accountability in the work being done on behalf of my patients, lost in a black hole of faxes and emails. It’s important to show where the patient is in their journey, where the process stands, whether an agent is handling it or automation is moving data between systems. Giving people visibility and the ability to drill down is critical.

Q: That’s an interesting viewpoint. You mentioned the front and back office and clinicians, but I didn’t realize patients might also have visibility into the system.

Michael: That’s certainly the vision for the future. Right now, our solution focuses on creating visibility and accountability for the care team—clinical and operational staff. But ultimately, the patient is part of the care team too. I would love to see a future where patients are assigned tasks and the rest of the care team has visibility into their progress. I think that’s inevitable. For now, we’re focused on giving the traditional care team the tools they need, but over time, I see patients and their home-based care team being part of that ecosystem.

Q: So I think we are almost at the end of the podcast. We would like to conclude by asking you what you think, maybe give a horizon of like a year and then maybe a five-year horizon. What do you think the top trends that are going to be in AI, and particularly for you at Dock Health? What are the three things that you are really keeping close tabs on and you feel that it’s going to really impact your product and be very transformational.

Michael: It’s tough to predict because AI is moving so fast. Moore’s Law doesn’t apply anymore—the doubling is happening every few months. Everything right now is AI, and “agentic” is the word of the day. I’ve even heard “ambient agents.” We see our role as orchestrating workflows where agents will carry out the majority of tasks.

When we started Dock Health, I imagined a day when it would be smart enough to handle processes automatically. AI has accelerated that roadmap by five to ten years, and the pace keeps shrinking. I truly believe that in the next five years, when healthcare spending in the U.S. reaches $10 trillion, the $2.2 trillion spent on administrative and operational costs may actually shrink because of operational efficiencies unlocked by AI.

We want to give care teams superpowers. Administrative and operational staff deserve better tools to do their work. Just as ambient scribes are now relieving clinicians from documentation, I believe AI will do the same for the administrative and operational burdens in healthcare. Within three to five years, I expect most of that work will be automated. Humans will still play a role, but much of it will feel like it just happens—almost magically.

If you zoom out five years from now, it will look like magic. But by then it will feel obvious. And that excites me, because at the end of the day, patients, our economy, and the world need more efficient care. The fact that we waste a trillion dollars a year on administrative tasks is shameful. Patients are asked to take on too much, like reminding us about referrals or tracking down lab results. These things happen because we’re human and don’t scale well. But now we have incredible tools at our fingertips, and I believe the next few years will be the most exciting time healthcare has ever experienced.

If we zoom out five years from now, it’s going to look like magic—but by then it will feel obvious. I’m excited for that future because, at the end of the day, patients, our economy, and our world need more efficient care. The fact that we waste a trillion dollars a year on administrative and operational tasks is shameful.

Too much of the burden falls on patients. Physicians and care teams often say, “Call me if you don’t get your referral in a couple of days,” or, as I saw with my own mom recently, patients are left chasing down lab results. These things happen because we’re human and we don’t scale well.

Now, we have incredible tools at our fingertips. That’s why I believe the coming years will be the most exciting time in healthcare that I’ve ever experienced—and likely the most exciting time the world has ever seen. Healthcare is primed for transformation and opportunity.

Q: Thank you for being with us on our podcast. It was a wonderful conversation, and we look forward to sharing your vision for the future with our listeners.

Michael: Thanks so much.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Day 3 – Diagnostics, Data, and the Dawn of Intelligent Care

Day 3 – Diagnostics, Data, and the Dawn of Intelligent Care

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

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Day 3 at HLTH USA 2025 was where boundaries blurred between breakthroughs in diagnostics, bioinformatics, and clinical intelligence — a powerful convergence making precision medicine accessible, scalable, and actionable. Conversations today revolved around how AI isn’t just augmenting care — it’s anticipating it.

From liquid biopsy breakthroughs to digital pathology and point-of-care testing innovations, the Diagnostics Zone became a hub for collaboration between AI, cloud, and clinical labs. Companies showcased advances that shifted healthcare from reactive to predictive — reducing diagnostic delays and driving early intervention across oncology, cardiology, and rare diseases.

The AI Zone was standing room only for Microsoft Health’s deep dive into contextual AI agents designed to accelerate provider insights in real time. Meanwhile, investor and startup dialogues underscored how trust and traceability in data pipelines remain central to AI’s adoption in diagnostics and population health.

Themes from the main stage extended this thread — with providers calling for smarter integration between diagnostic intelligence and reimbursement workflows, and innovators urging joint accountability between payers, developers, and clinicians.

Walking through the show floors, it was clear that HLTH isn’t just hosting dialogues — it’s brokering the future of connected care. In the words of one panelist: “Accuracy will always matter, but accessibility is where real impact begins.”

Tomorrow the event closes but today offered the clearest blueprint yet for AI-driven transformation that’s both ethical and executable.

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Day 2 – Scaling, Diagnostics, and AI in Action – Highlights from HLTH USA 2025

Day 2 – Scaling, Diagnostics, and AI in Action – Highlights from HLTH USA 2025

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

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Thanks for following along. Day 2 brought depth, signal and high-energy exchanges at HLTH USA 2025. I’m looking forward to what tomorrow brings — stay tuned for more insights from Las Vegas!

What stood out on Day 2:

  • Key thematic zones took centre-stage:
    • The AI & Emerging Technology Zone from ~10:00 AM to 4:00 PM, where practical deployment stories and ethical frameworks were front-and-centre.
    • The Diagnostics Zone ran concurrently, highlighting how imaging, molecular, data-driven diagnostics are positioning themselves differently.
    • The Pharma & Life Sciences track, was also active between ~10:00 AM and 4:00 PM, with interesting panels including how AI is reshaping drug development and distribution.
  • Award moments added high-energy: e.g., the “Digital Health Hub AI Awards,” “Diagnostics Awards,” and later the Women @ HLTH reception in the evening. HLTH+1

On the floor, I heard consistent themes such as scaling from pilot to production, moving beyond idealistic AI demos, and diagnostic-enabled value models (vs just imaging tech).

Key reflections for our global health-innovation community

  • AI is shifting from buzz to deployment: It’s clear now that the conversation is less “if we adopt AI” and more “how we embed AI responsibly across diagnostics, pharma and care delivery”.
  • Diagnostics is re-emerging as a core business model, not just a cost centre: With the Diagnostics Zone packed and panels discussing ROI, leadership is viewing diagnostics as strategic (e.g., early detection + data-driven care) rather than ancillary.
  • Pharma & life sciences are embracing tech-driven agility: On panels today, organizations shared how AI and diagnostics are entering earlier into the R&D and commercialization pathways — the ecosystem is consolidating around fewer, more integrated solutions.
  • Awards matter — they signal what the community values: Watching the Digital Health Hub Awards gave me a lens on what makers, investors and buyers are looking at: scalability, measurable outcomes, equity, and sustainability.
  • Networking remains where the magic happens: While the content is strong, the momentum lies in the pairings — whether it’s 1:1 matches via Investor Connect or spontaneous show-floor meetups. These informal connections often generate the most actionable insights.

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Day 1 – Kicking Off HLTH USA 2025: Big Ideas, Bold Voices, and Real Momentum

Day 1 – Kicking Off HLTH USA 2025: Big Ideas, Bold Voices, and Real Momentum

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

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It was an energizing start to HLTH USA 2025 here in Las Vegas! As host of The Big Unlock podcast and a media attendee, I spent the day immersed in conversations, sessions, and stories that set the tone for a transformative week ahead in healthcare innovation.

  • The event opened with a full slate of partner programs—from Value-Based Care to Pharma and Clinician tracks—each tackling the urgent need for integration, data transparency, and sustainable value creation in care delivery.
  • The opening keynote and welcome session brought palpable momentum. Mark Cuban’s fiery take on drug pricing and transparency reminded everyone that the business of healthcare must evolve to serve patients better.
  • AI was everywhere—not as a buzzword, but as a practical tool already reshaping clinical workflows, patient access, and decision-making. The message was clear: AI-native healthcare isn’t coming; it’s already here.

The networking floor buzzed with startups, investors, and providers exploring collaborations that could define the next generation of digital health solutions.

Some takeaways

  • Transparency and affordability are fast becoming the moral currency of healthcare innovation.
  • AI adoption has crossed the experimentation phase—the focus now is on scaling responsibly and proving measurable outcomes.
  • Ecosystem collaboration is the new competitive advantage; silos are dissolving as employers, payers, and tech companies seek shared wins.
  • And perhaps most importantly—the best insights often came from hallway conversations and spontaneous exchanges, not just the mainstage.

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Join Me at HLTH 2025 as We Unlock the Future of Health Together

Join Me at HLTH 2025 as We Unlock the Future of Health Together

Join Me at HLTH 2025 as We Unlock the Future of Health Together

Connect with Rohit on LinkedIn

Subscribe to The Big Unlock Podcast newsletter

“HLTH brings together the brightest minds in healthcare to drive real-world transformation through AI, data, and workflow innovation. The energy, collaboration, and actionable insights here are truly reshaping the future of care at scale.”

– Rohit Mahajan, Co-host of The Big Unlock Podcast

As HLTH USA 2025 approaches, I am filled with genuine excitement and anticipation for what promises to be an incredible gathering of healthcare visionaries, innovators, and leaders. HLTH has truly evolved into the heartbeat of healthcare transformation, a place where technology meets purpose and the future of health is actively shaped.

One of the most thrilling aspects for me this year is the focus on AI in healthcare. From predictive analytics and patient engagement to workflow automation and governance, the AI spotlight at HLTH is illuminating how health systems can accelerate adoption and drive meaningful outcomes. The conversations around AI Centers of Excellence are especially inspiring—they showcase real-world use cases where AI isn’t just an experiment but a scalable, trusted part of the clinical and operational fabric.

I will be speaking at the Future and Health: AI Centers of Excellence Summit during HLTH. This is where I’ll share insights on leveraging platforms, data fabric, and AI agents to power enterprise transformation. I am eager to contribute to calls for responsible AI use that elevates quality, safety, and most importantly, the patient and caregiver experience.

Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

Beyond the panels and sessions, what truly energizes me is the opportunity to reconnect with my peers and meet new industry leaders. HLTH brings together this remarkable ecosystem—tech innovators, clinicians, executives, investors—all passionate about pushing healthcare forward. Through The Big Unlock Podcast, I will be interviewing many of these incredible minds on-site, gathering firsthand stories about the challenges, successes, and breakthroughs shaping the AI-powered future.

The vibe at HLTH is unique—intense yet collaborative; visionary yet grounded in practical reality. There’s a collective drive to unlock new possibilities and to learn from one another’s journeys. It’s that spirit of openness and forward-thinking that makes HLTH more than an event—it’s a launchpad for the next wave of healthcare innovation.

For anyone interested in the future of health, HLTH is the place to be. Whether you’re passionate about AI, digital health, patient experience, or enterprise transformation, the energy and insights you’ll find here are unmatched. I’m looking forward to bringing back those voices and perspectives through the podcast, sharing episodes that inspire, challenge, and inform.

In the coming days, follow my journey at HLTH for exclusive interviews, thought leadership, and a front-row seat to the evolution of healthcare. Together, we’ll explore how AI and innovation are not just concepts but powerful tools unlocking better care for all.

Stay tuned and get ready to unlock the future of health with me at HLTH USA 2025!

Connect with Rohit on LinkedIn

Subscribe to The Big Unlock Podcast newsletter

Event Gallery

Day 1 – Kicking Off HLTH USA 2025: Big Ideas, Bold Voices, and Real Momentum

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

Share This Post

It was an energizing start to HLTH USA 2025 here in Las Vegas! As host of The Big Unlock podcast and a media attendee, I spent the day immersed in conversations, sessions, and stories that set the tone for a transformative week ahead in healthcare innovation.

  • The event opened with a full slate of partner programs—from Value-Based Care to Pharma and Clinician tracks—each tackling the urgent need for integration, data transparency, and sustainable value creation in care delivery.
  • The opening keynote and welcome session brought palpable momentum. Mark Cuban’s fiery take on drug pricing and transparency reminded everyone that the business of healthcare must evolve to serve patients better.
  • AI was everywhere—not as a buzzword, but as a practical tool already reshaping clinical workflows, patient access, and decision-making. The message was clear: AI-native healthcare isn’t coming; it’s already here.

The networking floor buzzed with startups, investors, and providers exploring collaborations that could define the next generation of digital health solutions.

Some takeaways

  • Transparency and affordability are fast becoming the moral currency of healthcare innovation.
  • AI adoption has crossed the experimentation phase—the focus now is on scaling responsibly and proving measurable outcomes.
  • Ecosystem collaboration is the new competitive advantage; silos are dissolving as employers, payers, and tech companies seek shared wins.
  • And perhaps most importantly—the best insights often came from hallway conversations and spontaneous exchanges, not just the mainstage.

Event Gallery

Day 2 – Scaling, Diagnostics, and AI in Action – Highlights from HLTH USA 2025

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

Share This Post

Thanks for following along. Day 2 brought depth, signal and high-energy exchanges at HLTH USA 2025. I’m looking forward to what tomorrow brings — stay tuned for more insights from Las Vegas!

What stood out on Day 2:

  • Key thematic zones took centre-stage:
    • The AI & Emerging Technology Zone from ~10:00 AM to 4:00 PM, where practical deployment stories and ethical frameworks were front-and-centre.
    • The Diagnostics Zone ran concurrently, highlighting how imaging, molecular, data-driven diagnostics are positioning themselves differently.
    • The Pharma & Life Sciences track, was also active between ~10:00 AM and 4:00 PM, with interesting panels including how AI is reshaping drug development and distribution.
  • Award moments added high-energy: e.g., the “Digital Health Hub AI Awards,” “Diagnostics Awards,” and later the Women @ HLTH reception in the evening. HLTH+1

On the floor, I heard consistent themes such as scaling from pilot to production, moving beyond idealistic AI demos, and diagnostic-enabled value models (vs just imaging tech).

Key reflections for our global health-innovation community

  • AI is shifting from buzz to deployment: It’s clear now that the conversation is less “if we adopt AI” and more “how we embed AI responsibly across diagnostics, pharma and care delivery”.
  • Diagnostics is re-emerging as a core business model, not just a cost centre: With the Diagnostics Zone packed and panels discussing ROI, leadership is viewing diagnostics as strategic (e.g., early detection + data-driven care) rather than ancillary.
  • Pharma & life sciences are embracing tech-driven agility: On panels today, organizations shared how AI and diagnostics are entering earlier into the R&D and commercialization pathways — the ecosystem is consolidating around fewer, more integrated solutions.
  • Awards matter — they signal what the community values: Watching the Digital Health Hub Awards gave me a lens on what makers, investors and buyers are looking at: scalability, measurable outcomes, equity, and sustainability.
  • Networking remains where the magic happens: While the content is strong, the momentum lies in the pairings — whether it’s 1:1 matches via Investor Connect or spontaneous show-floor meetups. These informal connections often generate the most actionable insights.

Event Gallery

Day 3 – Diagnostics, Data, and the Dawn of Intelligent Care

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

Share This Post

Day 3 at HLTH USA 2025 was where boundaries blurred between breakthroughs in diagnostics, bioinformatics, and clinical intelligence — a powerful convergence making precision medicine accessible, scalable, and actionable. Conversations today revolved around how AI isn’t just augmenting care — it’s anticipating it.

From liquid biopsy breakthroughs to digital pathology and point-of-care testing innovations, the Diagnostics Zone became a hub for collaboration between AI, cloud, and clinical labs. Companies showcased advances that shifted healthcare from reactive to predictive — reducing diagnostic delays and driving early intervention across oncology, cardiology, and rare diseases.

The AI Zone was standing room only for Microsoft Health’s deep dive into contextual AI agents designed to accelerate provider insights in real time. Meanwhile, investor and startup dialogues underscored how trust and traceability in data pipelines remain central to AI’s adoption in diagnostics and population health.

Themes from the main stage extended this thread — with providers calling for smarter integration between diagnostic intelligence and reimbursement workflows, and innovators urging joint accountability between payers, developers, and clinicians.

Walking through the show floors, it was clear that HLTH isn’t just hosting dialogues — it’s brokering the future of connected care. In the words of one panelist: “Accuracy will always matter, but accessibility is where real impact begins.”

Tomorrow the event closes but today offered the clearest blueprint yet for AI-driven transformation that’s both ethical and executable.

Event Gallery

Day 4 – Driving Action from Innovation

Picture of Rohit Mahajan

Rohit Mahajan

Co-Host of The Big Unlock Podcast

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Wrapping up Day 4 at HLTH USA 2025, the energy of this event remains strong—and with good reason. The conversations here long ago moved beyond ideas to tangible actions shaping the future of healthcare.

Today’s sessions and keynotes emphasized sustainable, equitable healthcare models anchored in AI and data-driven insights. What stood out most to me? The recognition that technology’s true value lies in how it delivers measurable impact—improving care access, outcomes, and provider workflows at scale.

The main stage brought leaders together around one common goal: aligning innovation with real-world healthcare challenges. From diagnostics to policy, from startups to enterprises, the message was clear—collaboration is essential to accelerate progress.

I was particularly inspired by the final partner meetings and exhibitor demos that spotlighted solutions ready for deployment today. This event has reinforced why HLTH remains the go-to platform for driving healthcare transformation forward.

As I reflect on these past days, I’m excited to continue uncovering and sharing stories that unlock the next chapter of health innovation through The Big Unlock Podcast.

Thank you to all the brilliant minds who made this year’s HLTH so impactful. Until next time—let’s keep turning breakthrough ideas into better health outcomes.

#HLTH25 #HealthcareInnovation #AI #HealthEquity #TheBigUnlock #DigitalHealth #RohitMahajan

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Transforming Behavioral Health by Merging Psychology with AI

Season 6: Episode #184

Podcast with Dr. Andreas Michaelides
Shaping Clinical AI with Google
Ex-Noom Chief of Psychology

Transforming Behavioral Health by Merging Psychology with AI

To receive regular updates 

In this episode, Dr. Andreas Michaelides, Clinical Psychologist helping shape Clinical AI with Google and Former Chief of Psychology at Noom, discusses the evolving intersection of technology and psychology, emphasizing how digital platforms and behavioral science can drive meaningful health outcomes at scale.

Drawing from his extensive experience at Noom and current role at Google, he highlights the value of integrating personalized care, education, and accountability through innovative technologies such as AI and wearables. Dr. Michaelides explores the ethical complexities and societal impact of AI-driven health solutions, underscoring the necessity for thoughtful governance and responsible implementation. He notes the transformative potential of predictive analytics and adaptive digital tools in enabling better assessments, interventions, and relationships between humans and technology.

Dr. Michaelides encourages practitioners to embrace uncertainty, unlearn traditional paradigms, and innovate by merging expertise with curiosity. While acknowledging fears around the rapid pace of tech advancement, he conveys an optimistic outlook on the future of digital health and behavioral change. Take a listen.

Video Podcast and Extracts

About Our Guest

Andreas Michaelides, Ph.D. Global Head of AI Advocacy at is a clinical psychologist and health-tech expert working at the intersection of behavior change and artificial intelligence.

As the former Chief of Psychology at Noom, he founded the company’s coaching and behavioral science teams — scaling the coaching program from 0 to over 3,000 coaches and leading the development of the first fully digital, CDC-recognized Diabetes Prevention Program.

Today, he’s shaping the future of health at Google, building AI-powered systems designed to drive real-world behavior change. With over 20 years of experience in behavior science and more than a decade integrating psychology, technology, and leadership, Andreas is focused on making wellness smarter, scalable, and deeply human.


Q: Hi, Dr. Michael Docktor, welcome to our Big Unlock podcast. We are really happy to have you as a guest on our show. Uh, it’s on our sixth season now, and, uh, we are looking forward to this conversation. I’m sure we’ll have a very engaging and interesting conversation about dog health, about healthcare in general, and the new trends about AI and all the buzzwords that people want to hear. Welcome to our show — we’d like to start with introductions. Happy to have you give your introduction. Thank you.

Michael: Yeah, thank you so much for having me. Yeah, I’m Michael Docktor, co-founder and CEO of Dock Health. I’m an ologist by trade. I am now on this, uh, healthcare venture outside of Boston Children’s Hospital where I started my GI career.

I was a busy clinician working on the clinical side as well as in innovation and informatics, and found that we had wonderful tools in the world outside of healthcare and struggled with my own challenges around managing all the tasks that are part of patient care. I found that I was using task management and project management tools that were not built for healthcare.

I scratched my head and wondered why we don’t have these things for healthcare. That was a journey. We started just over five years ago. We spun out Dock Health from Boston Children’s, and we’ve been on a very exciting journey in the world outside the academic walls since then.

It’s been fun. I’m excited to talk to you more about, uh, what we’re doing.

Q Great. That’s a great introduction. Thank you for letting our listeners know. We usually like to start with how you came into healthcare because everyone has an interesting story about what inspired them to become a physician.

For you, it’s particularly interesting because you’ve created this interface between design, technology, and healthcare — and you went beyond just visualizing what you wanted to do or asking why somebody doesn’t fix it, to actually building it yourself. I’d love to hear more about how you came into medicine and then into technology.

Michael: I could probably spend the entire podcast on this question. Obviously, my last name is Doctor, so there was some planting occurring there, and there’s something to be said for that.

One of my earliest memories was wanting to grow up to be a doctor. My younger sister had some GI issues when we were young, and I became very close with her gastroenterologist. I followed her on her journey and, unbeknownst to me, ended up following one of my mentors and was inspired to do the work for other children the way my sister was cared for. That was the initial inspiration.

You mentioned design. That’s interesting because my mother is an interior designer, my father is a dentist who specialized in aesthetics, and design — how things look, feel, and work — has always been part of my DNA. It was an amazing journey to go from being a traditional doctor in pediatric gastroenterology to discovering the importance of user experience and user interface.

Then the iPhone came out, then the iPad, and that really started me on my journey of exploring app development and software, and wondering why we didn’t use these wonderful devices in our pockets the way we should. That journey started more than 10 years ago and has led me to this perfect intersection of healthcare, design, and informatics, creating better experiences for patients and providers.

There’s a lot to unpack there, but people ask me if I would do it differently if I had the chance to do it all over — and absolutely not. I’m doing exactly what I want to be doing right now.

Q: Thank you for sharing that. That gives us so much perspective into how you came into this field, the influence of your parents, and how everyone around you inspired you to do this. That’s really interesting.

That leads us into how you built Dock Health. Tell us some examples of how you saw this becoming transformational in actual implementations with clients. When you built the tool, did you visualize exactly what it would do? Did it go beyond what you thought it would achieve in a healthcare setting? We’d love to hear more about that.

Michael: We’re far beyond where I ever thought we’d be when we first started this journey. That’s the exciting part. Fundamentally, we have such an administrative and operational challenge in healthcare. I saw it firsthand as a busy clinician struggling to manage all the clinically adjacent work that had to be done for my patients.

For example, I might have a patient with Crohn’s disease who needs to go to an infusion center. There are all these downstream tasks and administrative steps that need to be done by a team of people. We didn’t have assistants to do that, and the electronic health record wasn’t built for it.

A quarter of the $5 trillion spent in healthcare goes to administrative and operational challenges, and there really are no tools built for that. We rely on paper checklists, email, faxes, and spreadsheets to manage all the work happening outside the electronic health record.

For me, the realization was that I was using wonderful project management and task management tools to run software projects in my innovation and informatics roles—and yet nothing like that existed in healthcare. Patients, in many ways, are projects. There are tasks that form the essence of care, and they need to be tackled, managed, and collaborated on, with visibility and accountability across teams. That didn’t exist.

What we are now doing is serving as that productivity platform for healthcare, one that sits alongside the electronic health record in synergy, helping manage all the administrative and operational tasks of patient care in ways the EHR wasn’t designed for.

Some examples would be managing patient intake and all the processes associated with it. Referrals, inbound and outbound, with all the paperwork, eligibility checks, and faxes—those workflows are still incredibly manual. Referrals are a great example: 80% of referrals that come into major academic medical centers are still arriving by fax, despite the fact that they’re using Epic, a wonderful electronic health record.

These processes are still incredibly laborious, take too long, and are inefficient. Patient care suffers along the way. There’s a gigantic bottleneck around the administrative and operational work that moves patients through their journeys, and that’s what we’re focused on fixing.

Q: This is what we hear from a lot of our clients and other CIOs and C-suite leaders who come to our podcast—that this is one major problem with healthcare. It’s siloed, and the processes are really stuck in the dark ages.

We were talking to somebody from Athena, and they said they had an 800-person offshore center in India just to screen faxes. When a fax came in, one person looked at it to see if it was a pizza order or a referral. It sounds unbelievable in this day and age, but that’s how it works. I’m amazed to hear this from you as well. It’s remarkable.

Michael: Yeah. In fact, Athena is a partner of ours, and we’re working on referral management. It’s an incredibly antiquated process where everyone loses visibility. The amount of manual labor required to process these things is shocking in this day and age, when they can be handled through process automation, AI, and agents.

Q: Exactly. You’re talking about agentic, we’re talking about voice agents, and yet we’re still dealing with faxes. That’s really interesting to know.

Michael: There is reason to be hopeful. Healthcare is always many decades behind, but the adoption of AI is progressing more rapidly than I’ve seen any technology adopted in healthcare. There’s reason for hope.

Q: That leads into my next question, but before we get there, you mentioned Dock Health as a productivity platform. That’s what it does for doctors, clinicians, and patients. But when we talk to our doctors, clients, and health systems, the one word that always comes up is complexity. They deal with so many different systems and have to learn something new each time.

Where does Dock Health fit in? Is it another system they have to manage, or does it help reduce that burden?

Michael: Yeah, it’s all about reducing the burden and improving the user experience. That’s been fundamental to our belief system since the founding of the company.

First and foremost, we’re trying to become the productivity platform and the hub that handles the administrative and operational work. Instead of being “another system,” we’re often replacing spreadsheets, paper checklists, emails, and faxes—the ways we’ve traditionally managed the 50% or more of administrative and operational tasks required for patient care.

The EHR is great for clinical work, billing, prescribing, and scheduling, but so much happens downstream that isn’t covered. I’d argue we are creating the hub for that. Just as the EHR is the clinical hub, Dock Health serves as the operational hub. Together, it’s really one plus one equals three.

We’re also aiming to be much more consumer-like in our approach. Our tool can onboard a customer in 30 minutes. We offer a free trial, and for small organizations that want to get up and running, they can start using it right away—just like downloading an app. It’s lightweight, highly configurable for end users, and designed with a strong focus on user experience.

The real challenge is that clinicians don’t want another tool. They’re busy and need to spend their time in the EHR. Our core users are often the super users: front office staff, back office teams, operational leaders, and administrative staff who leverage our tool every day.

The important piece is that we connect to the electronic health record and provide visibility for clinicians. If they’re interested, they can see where a patient is in their journey or where a process stands, but they don’t have to be in our system all day, checking tasks or learning another workflow.

The intent is to provide that operational hub for administrative and support staff—the essential members of the care team—while clinicians continue their work in the EHR and often drive tasks into our system through their orders and actions there.

Q: Is the integration with the EHRs native, like with Epic, Cerner, and the big ones?

Michael: Yeah. We’re on the marketplace with a number of the top EHRs, including Epic and Cerner. We’re also working with Mayo Clinic, their Mayo Clinic Platform, and their Deploy platform.

The other thing I’d mention is that many organizations use our tools without being integrated with the electronic health record. That’s often because they’re smaller practices—mental health, concierge care, or primary care—that simply need a hub to handle administrative and operational work and collaborate as a team.

We spend a lot of time helping organizations define their processes, and those processes can then live in Dock, where they can be collaborated on and turned into operational best practices. That’s something that often doesn’t happen in traditional healthcare organizations, and our tool is valuable even when it’s not connected to an EHR.

Of course, the real value comes when we integrate with systems—EHRs, CRMs, patient engagement tools—and serve as the hub while automating as many tasks as possible. That’s when the flywheel starts turning, and organizations begin to feel the benefits of automation and work reduction. It ultimately moves the needle in a measurable way.

Q: So, you’re saying if there’s an integration with the EHR, then it’s end-to-end and people can see a complete view of what’s happening. But even without the EHR, because it helps with workflow management, it’s valuable for practices?

Michael: It’s just like every other industry. They have Asana, JIRA, Trello—all these tools where a lot of the real work gets done. That provides value in itself by giving a clear view into where the patient is in their journey and what process they’re following.

When we integrate with an EHR or other systems, we can then automate those workflows. For example, when a fax comes in, we can launch a workflow for a new patient referral. When a lab order is placed, we can launch a workflow for follow-up. Or when a patient has a procedure, we can launch a process for their downstream follow-up.

Q: That leads into the next question, which is your learning journey with AI. What advice do you have for our listeners about where AI is headed? And with voice agents and agentic tech being buzzwords, where do you see Dock Health going? Are you also looking at implementing voice agents?

Michael: AI is incredibly exciting. I’ve put it out there that we’re an AI-first company. We’ve been thinking about this for a while, and we already have what we call Dock Intelligence in production with customers. We started with the basics, using foundational models and generative AI to process large troves of data.

Now, we can summarize all the work being done for a patient and create a snapshot for the end user—showing all tasks, workflows, patient context, and even clinical context if available. That gives a quick overview of what’s happening. Users can edit that snapshot if needed, or generate a note that writes back to the EHR to keep the operational and clinical record in sync.

That’s the first step in our AI journey. From there, we realized tasks bundle into workflows, workflows can be automated, and now we’re starting to farm out those tasks to agents and AI. For example, a voice agent could follow up with a patient to confirm a referral or review lab results. We’re actively pursuing that, as well as leveraging AI to extract data from faxes to automate referral processes.

AI is the big unlock. In the next three to five years, I believe most administrative and operational tasks will be handled by automation and AI agents orchestrating together. These agents need rails to run on and structure to guide them, and end users must remain in the loop to provide oversight and visibility. But the lion’s share of this work will be handled by agents—and we’re building that future right now.

Q: Are you aligning specifically with any particular LLM or provider, or are you going to be completely agnostic?

Michael: I’d like to think we’ll be agnostic. We’re doing plenty of building on some of the foundational models ourselves, and we’re partnering where we can with great tools. For example, with voice agents, we’re not necessarily building them ourselves—there are excellent options out there. What we are doing is building our own homegrown AI agents that can manage processes and facilitate handoffs from task to task.

Our approach has always been to recognize that there’s a wonderful ecosystem out there. We want to be the hub that connects to the best-of-breed systems—whether that’s Epic as an EHR, Salesforce as a CRM, or other tools we can leverage to create a healthy ecosystem. That’s what we’re pursuing.

Q: I wanted to ask a question about that because with the LLMs, one of the main problems is the hallucinations or the repeatability or the trust factor there. So I saw that Dock is HITRUST certified. So, I just wanted to ask, what are your views on that? Because in terms of using generative AI when we talk to our clients, uh, for implementations on LLMs, or they’re more comfortable certainly with the administrative tasks, but even with the administrative tasks there’s always the question of what are the guardrails you put around that and how do you make sure that the results that you are seeing or you are displaying on Doc Health, you know, stay within that, those bounds of accuracy. Whathat are your thoughts around that?

Michael: AI is incredibly exciting—it’s moving at the speed of light, and everyone wants to benefit from it. I do think administrative and operational areas of healthcare are lower-hanging fruit and far less risky. We’re not yet in a place where we can reliably use AI for absolute clinical decision support and autonomy, though I believe we’ll get there in the not-too-distant future.

For now, the clunky and manual administrative work is ripe for AI. Still, we need to be mindful of potential hallucinations. In our experience so far, we haven’t seen issues, but we’ve put safeguards in place. That means keeping a human in the loop to ensure outputs are appropriate and relevant. We also give users the ability to edit results before they’re sent—whether it’s a summary being emailed to a colleague or written back into the EHR as a clinical note.

It’s essential to show your work. If we’re pulling data from various sources, we show those sources. We keep users in the loop, give them control to review and edit, and maintain tight feedback loops to catch and address anything off.

So far, even foundational LLMs have been surprisingly strong in our relatively narrow use cases. The real challenges will come as we move toward higher-risk clinical decision support—but I’m confident we’ll get there quickly.

Q: It’s interesting you mentioned humans in the loop and the fact that people can review or edit what’s being generated. But with agents, one of the key defining characteristics is autonomy—they can make API calls, send emails, even browse the web to find and act on information. How do you think about that level of control being handed over?

Michael: I think it’s all about balance. The value of task automation and workflow automation is clear. For us, one of our strengths is providing a user interface where the end user can actually see where a process is in its journey.

We’re working on features like showing confidence levels or confidence intervals for data extracted—for example, from a fax. That way, we not only show our work but also give transparency into how accurate that extraction might be. Using our interface, which breaks workflows into tasks, we can show exactly where a process stands. If we believe human involvement is needed, we assign a task and call someone in to review.

Even in the agentic future—which is already upon us and actively being built and tested—we see ways to keep humans in the loop. Operating entirely in a vacuum is risky. Part of my mantra, coming from clinical practice, is that I lacked visibility and accountability in the work being done on behalf of my patients, lost in a black hole of faxes and emails. It’s important to show where the patient is in their journey, where the process stands, whether an agent is handling it or automation is moving data between systems. Giving people visibility and the ability to drill down is critical.

Q: That’s an interesting viewpoint. You mentioned the front and back office and clinicians, but I didn’t realize patients might also have visibility into the system.

Michael: That’s certainly the vision for the future. Right now, our solution focuses on creating visibility and accountability for the care team—clinical and operational staff. But ultimately, the patient is part of the care team too. I would love to see a future where patients are assigned tasks and the rest of the care team has visibility into their progress. I think that’s inevitable. For now, we’re focused on giving the traditional care team the tools they need, but over time, I see patients and their home-based care team being part of that ecosystem.

Q: So I think we are almost at the end of the podcast. We would like to conclude by asking you what you think, maybe give a horizon of like a year and then maybe a five-year horizon. What do you think the top trends that are going to be in AI, and particularly for you at Dock Health? What are the three things that you are really keeping close tabs on and you feel that it’s going to really impact your product and be very transformational.

Michael: It’s tough to predict because AI is moving so fast. Moore’s Law doesn’t apply anymore—the doubling is happening every few months. Everything right now is AI, and “agentic” is the word of the day. I’ve even heard “ambient agents.” We see our role as orchestrating workflows where agents will carry out the majority of tasks.

When we started Dock Health, I imagined a day when it would be smart enough to handle processes automatically. AI has accelerated that roadmap by five to ten years, and the pace keeps shrinking. I truly believe that in the next five years, when healthcare spending in the U.S. reaches $10 trillion, the $2.2 trillion spent on administrative and operational costs may actually shrink because of operational efficiencies unlocked by AI.

We want to give care teams superpowers. Administrative and operational staff deserve better tools to do their work. Just as ambient scribes are now relieving clinicians from documentation, I believe AI will do the same for the administrative and operational burdens in healthcare. Within three to five years, I expect most of that work will be automated. Humans will still play a role, but much of it will feel like it just happens—almost magically.

If you zoom out five years from now, it will look like magic. But by then it will feel obvious. And that excites me, because at the end of the day, patients, our economy, and the world need more efficient care. The fact that we waste a trillion dollars a year on administrative tasks is shameful. Patients are asked to take on too much, like reminding us about referrals or tracking down lab results. These things happen because we’re human and don’t scale well. But now we have incredible tools at our fingertips, and I believe the next few years will be the most exciting time healthcare has ever experienced.

If we zoom out five years from now, it’s going to look like magic—but by then it will feel obvious. I’m excited for that future because, at the end of the day, patients, our economy, and our world need more efficient care. The fact that we waste a trillion dollars a year on administrative and operational tasks is shameful.

Too much of the burden falls on patients. Physicians and care teams often say, “Call me if you don’t get your referral in a couple of days,” or, as I saw with my own mom recently, patients are left chasing down lab results. These things happen because we’re human and we don’t scale well.

Now, we have incredible tools at our fingertips. That’s why I believe the coming years will be the most exciting time in healthcare that I’ve ever experienced—and likely the most exciting time the world has ever seen. Healthcare is primed for transformation and opportunity.

Q: Thank you for being with us on our podcast. It was a wonderful conversation, and we look forward to sharing your vision for the future with our listeners.

Michael: Thanks so much.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Bridging the AI Gap in Healthcare with AI Literacy and Trust

Season 6: Episode #183

Podcast with Jan Beger,
Global Head of AI Advocacy,
GE HealthCare

Bridging the AI Gap in Healthcare with AI Literacy and Trust

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In this episode, Jan Beger, Global Head of AI Advocacy at GE HealthCare, shares his mission to bridge the gap between the conceptual promise and real-world impact of AI in healthcare. He stresses on the critical need to build AI literacy and trust among clinicians, executives, and students, and explains why a human-centric approach and strong change management are critical for successful adoption.

Jan highlights GE’s global AI literacy programs that train employees and clinicians on responsible use, practical applications, and critical evaluation of AI. He highlights how moving beyond pilots to strategic, systemwide deployment requires continuous education, executive engagement, and a focus on change management. He also spoke about GE’s successes such as improved efficiency in software development and innovations like AI-guided handheld ultrasound devices that democratize imaging by supporting users of varied expertise, as well as the challenges of keeping AI tools robust and up-to-date.

Jan addresses the future of the workforce, noting that adaptability and tech fluency will be essential as 70% of job skills evolve by 2030. He encourages healthcare leaders to see AI not just as technology, but as a transformative tool to enhance care and outcomes. Take a listen.

Video Podcast and Extracts

About Our Guest

Jan Beger Global Head of AI Advocacy at GE HealthCare, is on a mission to transform AI in healthcare from a conceptual promise into a practical, high-impact reality by equipping healthcare professionals with the knowledge and skills to drive this change.

With over 20 years of experience in healthcare informatics, medical imaging, and artificial intelligence, Jan bridges the gap between cutting-edge technology and real-world application. His work makes AI accessible, understandable, and actionable for healthcare professionals worldwide.

As Executive Director of HelloAI, a strategic educational initiative supported by EIT Health, Jan leads efforts to enhance AI literacy among healthcare professionals, medical students, researchers, and IT specialists. The program, which has reached over 3,500 participants across 70+ countries, offers a flexible, self-paced learning experience enriched by live online events. Through HelloAI, participants gain practical AI skills, empowering them to confidently integrate AI into clinical and operational workflows.

Beyond education, Jan focuses on driving real-world AI adoption. He founded Edison Accelerator, a start-up acceleration and healthcare provider collaboration program, developed by GE HealthCare in partnership with Telefónica’s Open Innovation Hub. This initiative connects healthcare providers, industry leaders, and startups to co-develop and integrate AI-enabled digital solutions, accelerating healthcare’s digital transformation.

Recognizing the importance of early AI education, Jan also founded GR4AI.Academy, a non-profit organization dedicated to helping children understand AI’s societal impact. Through this initiative, the academy provides a balanced perspective on AI’s opportunities and challenges, equipping future generations with essential AI knowledge from an early age.

Jan is committed to advancing AI literacy and adoption, empowering healthcare professionals to navigate and shape the future of AI. By providing the right knowledge and skills, he enables them to leverage AI effectively—enhancing decision-making, optimizing workflows, and improving healthcare delivery. His work ensures that AI is not just a technological advancement but a practical tool that supports clinicians, streamlines operations, and ultimately benefits patients.


Ritu: Hi Jan, welcome to our podcast. We are so happy to have you here on The Big Unlock podcast, season six, and we are headed to 180 plus episodes now. Really great having you on the show today. Just a brief introduction — my name is Ritu Roy. I am the Managing Partner here at BigRio and Damo Consulting and a co-host of The Big Unlock podcast with Rohit. And with that, I’ll hand it over to Rohit. He can give a brief introduction and then over to Jan. Thank you.

Rohit: Hi Jan, great to have you here, like Ritu said, and thank you for making the time in the evening from where you are in Germany. Really excited to have this conversation. I’m Rohit Mahajan, CEO and Managing Partner at BigRio and Damo Consulting. And with that, Jan, would you like to start with your intro?

Jan: Absolutely. First of all, thank you both for having me today and for the invitation. Truly appreciate it and looking forward to a good conversation about this exciting topic of artificial intelligence in healthcare. As you mentioned, my name is Jan Beger, Head of AI Advocacy at GE Healthcare. My mission is to transform AI in healthcare from a conceptual promise into a high-impact reality. I focus on equipping healthcare professionals, executives, and the next generation—like students—with the knowledge, skills, and mindset to thrive in this AI-enabled future of healthcare.

Ritu: That’s really great. Wonderful introduction and really interesting title you have, Jan, because we’ve talked to CIOs and CMIOs, but you’re someone who’s the Head of AI Advocacy. I think that’s something new. Would love to hear about your journey—how you came to be in this role, how you combine expertise in healthcare and AI, and what your vision for AI is at GE Healthcare.

Jan: Thank you so much. I hope you agree—based on the many conversations you’ve had in this space with different experts—when we talk about AI in healthcare, those conversations very quickly get technical. But I think in healthcare, and maybe as an entire industry, we have not focused enough on one important aspect: making sure that those clinicians and healthcare professionals we expect to use AI technologies are taken with us on this technology journey.

So, things like change management and education—making sure we focus on the human aspect—is something I think has not been emphasized enough across the industry, maybe even to a point that it slows down AI adoption. This is what I’m really focusing on—what we need to do to remove worries and fears among healthcare professionals, help them gain a solid understanding of the technology, build basic trust in AI, and get them interested in testing and piloting these solutions. Ultimately, the idea is this could lead to faster adoption.

Ritu: Yeah, that’s an extremely valid point, Jan, because I was just at a conference at MIT yesterday, and this was one of the key things that came up — that it can’t be a top-down approach because whenever you ask somebody to do something, their initial reaction is to go into defensive mode and say, “Why should I do something that’s going to take my job away?” or “What’s in it for me?”
So we would be really interested in hearing from you how you are able to get buy-in from the teams across GE and get everybody on board, making sure everyone has the literacy skills, like you said, to understand that AI can actually be a tool to do your job better, increase productivity, bring efficiency, and do all the good things AI promises.

Jan: First of all, I think across different domains and industries — in a health system, but the same in a medtech or healthtech company — everything is being reinvented right now in real time. There’s a lot of activity in that space.
We at GE also look into processes and how we can support our workforce with generative AI technologies. Again, the technology is one part of the story; the second is how we make sure we enable our workforce — 51,000 employees across the globe in 160 countries — to leverage this technology well and responsibly, to truly make a difference in their day-to-day work.

This is exactly the same in the healthcare space as well. We are entering a state of skill redefinition in real time. Things that were important in the past — like routine execution, static expertise, or hierarchical knowledge — are becoming less relevant. And on the flip side, we see more important skills emerging, like adaptability, systems thinking, tech fluency, and AI know-how.

We all have to prepare for this. There was a study recently done by Workday and LinkedIn, which said that 70% of job skills are expected to change by 2030, with AI driving much of this shift. This is not just healthcare — this is across different industries.
Maybe in healthcare, this kind of change will feel a little bit slower because it’s highly regulated. But what I want to say by mentioning this number is that there is a massive technology transformation ahead of us, and a lot of people don’t even understand that this is coming — and coming with quite some impact.

We not only need to continue building great technologies and integrating AI into products and workflows, but also need to create awareness and build AI literacy so that everyone across the healthcare ecosystem can use this technology responsibly for better care and improved patient outcomes.

Ritu: Thank you, Jan. That answer leads into two follow-up questions. First, like you said, the speed of invention is at an unprecedented scale, which we haven’t seen before. The speed is also leading to democratization, where anybody can do low-code or build a tool or a prototype.
That leads to the next thing — this whole concept of AI literacy. If the tools are so easy to use and can unlock so many new ideas, you want everybody across the company to understand how to use them and be fluent. So, how does GE, with such a large employee base — 51,000 employees across 161 countries — handle this? Do you have an overall AI literacy program with different levels, or what systems are you setting up to address this?

Jan: Great question. First, I should define what AI literacy means to me, because it could mean different things for different people.
In a nutshell, I would say it’s three things: one is the competencies required to collaborate responsibly with AI and interact with technologies such as large language models and generative AI.
The second is to be able to explain their outputs.
Third, it’s to be able to critically evaluate those outputs — and then do something meaningful with them. As you know, the worst thing would be to blindly trust those outputs and leverage them in your day-to-day work. So, critical evaluation is a very important part of AI literacy overall.

At GE Healthcare, there is an AI literacy program in place, which is part of a broader Responsible AI strategy. We have different ways to educate our teams — live sessions where they can dial in and learn from experts on how to use generative AI integrated into our tech stack, best practice sharing sessions, and self-paced learning offerings for employees at different levels — from a foundational course covering basic AI terminology to more use-case-specific, in-depth training for specific groups and roles.

Rohit: I was just wondering, Jan, about the key initiatives you’re taking, which are so valuable moving forward for the company and the employees themselves, because they’re basically increasing their skillset as well. We’ve been thinking about some success metrics for our own organization and for some of our clients who’ve been asking for similar services. Any thoughts or ideas, Jan, on what success metrics one could track for such initiatives in any organization setting out on this journey?

Jan: I think those success metrics and KPIs are critically important to measure traction and see where we’re heading and if the investment in these efforts makes sense. For instance, one area where we’ve seen early positive results is with our software developers. With AI capabilities, we’ve seen improvements in speed—getting code done, getting code reviewed, those kinds of things.
So this is maybe one area where, across industries, we already have several best practices and standard ways to measure performance and progress. But then there are other groups of employees where those measures are harder to obtain, or maybe it’s too early because we just started using these capabilities.

For instance, our field engineers—people who visit customer sites to check or repair MRI devices—now get AI support through tools we’ve developed where they can have a natural language conversation with the service manual of a specific device or get help with scheduling. Those are new use cases, and we’re still defining the right success measures or KPIs for them.
There’s a wide range of capabilities and use cases across different groups and business units. Over time, we’re getting better at measuring progress. As I mentioned, in software development we already have specific measures in place and are seeing the benefits of AI, but there are other areas where it’s still greenfield, and KPIs will evolve over time.

Ritu: Thank you, Jan. Our listeners—and most of us—always like to hear about success stories and success metrics, but it’s also important to learn from failure. It would be really interesting to hear from you about a couple of cases where things didn’t go so well, what you learned from that, and how you came back to do something even better.

Jan: I’ll give you an example of a tool we built in-house to support our marketing teams with approved external communication content. We’re feeding a retrieval-augmented generation model with external content so that when a communications specialist gets a request from the media, they don’t need to start from scratch—they can leverage this chatbot, get approved responses, tweak and refine them, and then use them.
It’s useful, but it’s also a lot of work—making sure the knowledge base of the chatbot is always up to date. Maintenance is a challenge and requires manpower and effort. So it’s not just a one-off where you build a cool AI tool and send it out for people to use. A lot of those tools require continuous focus, effort, and maintenance.

Rohit: While you do this at such a global scale, are you traveling a lot and meeting people in person to motivate them, or are you using online tools to make this happen? What are some of the key tools or methods you’re using for the advocacy you’re doing with such a large group of people?

Jan: That’s a great question. When I introduced myself, I should have mentioned that I focus most of my time on our customers—health systems, hospitals, and healthcare professionals—and focus my AI advocacy and literacy work mainly on clinicians.
To answer your question, I travel about 80% of my time. I’ll be in the US next week in Seattle and Atlanta. It’s important to meet medical and clinical experts in person. I always learn from them—I want to understand their concerns, fears, issues, what works, and what doesn’t. Even with great remote technology, face-to-face works best for me.

Of course, there are things that can be done online too. For example, for a few years we’ve been running an AI literacy program for healthcare professionals called Hello AI. When you go to helloai-professional.com, you’ll find more information. It’s a self-paced e-learning offering with two modules where clinicians, students, researchers, and executives can educate themselves about AI in healthcare.

We’ve received great feedback. So far, we’ve educated more than 5,000 healthcare professionals from over 70 countries. Later this year, we’re launching a new learning module built specifically for healthcare executives—because this population is becoming increasingly important in the overall transformation.
Over the last few years, healthcare systems have made progress adopting and piloting AI, but mostly through point solutions—like a decision-support tool in radiology or something with EHRs. Executives now need to think about AI strategically—how to plan, deploy, and measure ROI at a system level. That’s why we’re launching this new offering for healthcare executives on the Hello AI platform later this year.

Rohit: That is fantastic. I think there’s definitely a need for such a thing. Tell us a little more about Hello AI. How did it come into being? Did it precede your joining GE Healthcare, or is it a GE Healthcare initiative? We’d love to learn more about this venture.

Jan: Thank you so much. First of all, when we think about AI in healthcare, there’s often the impression that this is a domain led by big tech or the innovative healthcare AI startup ecosystem around the globe. But that’s only partially true. The reality is that when you look into AI and machine-learning-enabled medical devices, you’ll quickly realize that it’s also a huge play for traditional medtech.
Companies such as GE Healthcare and Siemens Healthineers are leading the pack. The FDA has authorized more than 1,000 AI-enabled medical devices so far, and about 100 of those come from GE Healthcare.

We feel a responsibility as a leader in this field not only to build and integrate great technologies into our devices but also to focus on the change management and education for those we expect to use these technologies. This is how it started—and what Hello AI is.

It’s a learning offering for healthcare professionals and executives built by a network of partners—GE Healthcare, universities, and technology companies—working together to spread the word. Our mission is to make AI literacy accessible and affordable for healthcare professionals worldwide.

We’re trying to provide healthcare AI–specific education, not just general AI education. There’s a lot of free AI content online from big tech, but we focus on healthcare-specific AI education at no or low cost. For instance, we currently have two modules: a free foundational course for everyone, and a more in-depth Professional course with 25 hours of content for just $99.

Rohit: That’s awesome. Would you be open to licensing this as well? In case a large enterprise is interested in your offerings, I’m sure you’re looking at some licensing deals too.

Jan: Our partnership model is threefold. First, we look for partner institutions to join Hello AI and co-develop new content. AI is a fast-paced field, and there’s a lot happening. For instance, earlier today we had a session on federated learning, which is part of new content we’re adding to our modules.
Second, we focus on co-marketing and co-promotion.
Third, when an institution joins us and contributes in these areas, we provide their employees or members free access to Hello AI content.

Rohit: That’s awesome. This is great—you’re offering such a robust platform to increase awareness and education in this space. As we come to the end of the podcast, Jan, any other thoughts or predictions in AI? There’s a lot of agentic AI coming our way—any thoughts for the future audience?

Ritu: And I think Jan wanted to show the device, which might relate to my question: do you have an example where AI has made a difference in patient outcomes—something you’ve put into a device that really made an impact?

Jan: Maybe just quickly, Rohit. I’ll share a use case that’s been very impactful, and then I’ll give a few takeaways. First, as I showed earlier, this is a handheld wireless ultrasound scanner for specific use cases. Imagine an emergency doctor carrying this wherever they go—a powerful imaging tool with no radiation. But one limitation is that it’s very operator-dependent. You need a certain level of education and experience to get high-quality medical images.

So a few years ago, we embedded AI into these machines. It tells you, while scanning the patient, how to move the probe to get high-quality images. This means even less-experienced clinicians can achieve excellent results. The idea is to democratize ultrasound so it’s accessible to more users. That’s just one of many examples of AI making an impact in healthcare today.

A few takeaways for your audience:
First, I strongly recommend everyone—whether in tech, corporate, or healthcare—start rethinking their job descriptions with AI in mind. Think about what you do every day, how AI could support you, and how it changes your role. When you start thinking this way, you’ll begin learning about AI, open your mind to opportunities, and adopt the right mindset to embrace this technology.

Second, we have so many great AI experts, data scientists, and developers worldwide working in industries like gaming or banking. If you know them, tell them about healthcare. If they truly want to make an impact on society, they should consider joining healthcare. It’s still early-stage and slower because of regulation, but if you have this expertise, the industry would truly value it. We can make a real difference here.

Ritu: Thank you, Jan. This was awesome. I’m sure listeners have a lot to absorb and reflect on. Your call to action is excellent—this is an industry where we can see the maximum impact and really help people. Thank you.

Jan: Thank you so much for inviting me.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

 

 

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Harnessing AI to Transform Innovation in Pharma and Healthcare

Harnessing AI to Transform Innovation in Pharma and Healthcare

Harnessing AI to Transform Innovation in Pharma and Healthcare

In the rapidly evolving world of pharmaceutical research, few organizations embody the promise of artificial intelligence (AI) as comprehensively as Eli Lilly. With a legacy spanning 150 years, Lilly is one of the world’s most established pharmaceutical companies and also the most comprehensive adopters of AI across its value chain, from drug discovery to patient care.

In one of the recent episodes of The Big Unlock podcast, our CEO Rohit Mahajan, and Managing Partner Ritu M. Uberoy interviewed Thomas Fuchs, Chief AI Officer at Eli Lilly, whose journey in AI and healthcare provides valuable context for the company’s current strategy. Thomas’ career has spanned academia, startups, and large-scale innovation, including FDA-approved AI systems in oncology. His deep-rooted belief in the power of code to improve human health has shaped his mission at Lilly that is to make AI a driver of medical breakthroughs at scale.

From Early Curiosity to AI in Healthcare

Thomas’ fascination with AI began early, inspired by a childhood viewing of 2001: A Space Odyssey. Later, during his academic work, he encountered one of the earliest demonstrations of neural networks distinguishing between cancerous and non-cancerous tissue. “Being able to help people by writing code is something amazing,” he recalls—a realization that propelled him into decades of work at the intersection of machine learning and medicine.

After roles at institutions like Memorial Sloan Kettering Cancer Center and Mount Sinai, and founding multiple startups including Paige.AI, which built frontier AI models for pathology and achieved the first FDA breakthrough designation in oncology AI, Thomas now brings that entrepreneurial mindset to Lilly. He emphasizes – “At Lilly, we have the enormous opportunity to reach millions of patients.”

A Thousand AI Projects and Counting

What sets Lilly apart is the breadth of AI adoption. Unlike startups focused on a single use case, Lilly is running over 1,000 active AI projects across its global operations. The company maintains a centralized AI registry to track projects, ensuring that innovation remains coordinated and impactful.

Applications span nearly every domain of the pharmaceutical value chain including:

  • Drug Discovery – AI models co-design novel molecules for small molecules, large molecules, and genetic medicines, accelerating research and improving the odds of success.
  • Regulatory Documentation – Large language models (LLMs) assist in drafting submissions to regulatory agencies, streamlining workflows for highly complex processes.
  • Manufacturing – Digital twins and computer vision systems optimize production lines, boosting throughput and reducing errors.
  • Commercial Operations – AI supports sales teams with route planning, physician outreach, and forecasting.
  • Financial Planning – Time-series models help forecast performance across Lilly’s profit centers.

This sweeping strategy reflects a clear goal – to use AI not just as a point solution but as a transformational lever across every aspect of drug development and delivery.

Success Stories in AI-Driven Innovation

Lilly’s AI portfolio includes several standout initiatives that demonstrate both scientific impact and practical value:

AI-Powered Drug Discovery: Lilly’s internal teams are building foundation models from scratch using decades of proprietary data, including reaction data from more than 20 years of experiments. These models support property prediction, de novo molecular design, and candidate selection. In some cases, AI has already co-designed leading molecules for critical targets, showcasing how digital innovation can complement human expertise.

Manufacturing Innovation: Computer vision models, such as vision transformers, have been deployed in quality control for injection lines, increasing throughput by millions of units. This is a tangible example of AI improving efficiency and scalability in pharmaceutical manufacturing—an area often overlooked in discussions about drug discovery.

Knowledge Access with “Chat in the Box”: Lilly has created an internal system called Chat in the Box, which enables employees to build specialized chatbots to search and analyze organizational knowledge. Hundreds of such bots are now in active use, helping teams work smarter and faster across departments.

These examples underscore Lilly’s approach – blending cutting-edge AI with practical use cases that solve real-world problems and deliver measurable results.

Building Trust and Human Oversight

While the technology is powerful, Thomas emphasizes that AI at Lilly is never about blind automation and human oversight and co-development remain central to every project.

He notes that, “One thing that never works is developing something outside and then trying to throw it over the fence into the application area.” Instead, Lilly embeds AI teams alongside scientists, physicians, and business experts to ensure solutions address real needs and integrate seamlessly into workflows.

Transparency is equally important. Thomas stresses the need to set realistic expectations avoiding both the hype that portrays AI as “magic” and the skepticism that dismisses it as unreliable. Clear communication about what AI can and cannot do builds organizational trust and supports broader adoption.

The Role of Data: A Moving Target

Lilly’s 150-year history provides a unique advantage: vast troves of proprietary data. Unlike many organizations still struggling with siloed or fragmented datasets, Lilly’s data infrastructure was surprisingly well-prepared when Thomas arrived.

Yet challenges remain. New devices and labs generate continuous streams of fresh data, while legacy datasets require ongoing integration. To keep pace, Lilly combines real-world data with synthetic data generation, enabling training at scales otherwise impossible. Thomas compares this to the self-driving car industry, where models must generate more training data than could ever be collected from real-world driving.

This hybrid approach, leveraging both historical data and lab-in-the-loop experiments, enables Lilly to train frontier AI models that push the boundaries of what’s possible in drug discovery.

Educating and Empowering a Global Workforce

Fostering AI literacy across the organization is a key priority. Lilly requires staff in its technology divisions to complete foundational AI training and has appointed AI “change champions” across departments to promote adoption and surface new ideas. The result is a dynamic feedback loop where employees not only use AI tools but also contribute insights that feed into a central registry of projects. This democratized approach ensures that innovation emerges from every part of the organization not just the C-suite or R&D labs.

Challenges in a Regulated World

Pharmaceuticals operate in a uniquely complex regulatory environment. Lilly must comply with requirements from the FDA, EMA, and dozens of other agencies worldwide. This means innovation must balance speed with safety.

In research settings, teams are encouraged to “fail fast,” running proof-of-concept pilots in as little as two weeks. But in areas involving patients or regulators, rigorous quality systems and compliance structures are essential. As Thomas puts it, “You can run fast and break things in research, but you cannot do that when you are patient-facing.”

The Future of AI in Pharma

For Thomas, the future of AI in pharmaceuticals is both exciting and demanding. He identifies several key trends shaping the road ahead:

  1. De Novo Drug Design at Scale
    AI is accelerating the generation of synthesizable, high-quality molecules. While new medicines can’t be developed as quickly as AI-generated text, the ability to propose and refine candidates at unprecedented scale represents a paradigm shift.
  2. Rethinking Clinical Trials and Regulatory Processes
    Traditional submissions can span 100,000 pages—documents that regulators themselves may soon analyze with AI. Fuchs envisions a future where agencies and companies exchange structured data directly, reducing timelines and accelerating access to safe, effective therapies.
  3. Democratizing Access to Medicines
    Manufacturing advances, robotics, and global distribution strategies will play a pivotal role in ensuring therapies reach patients everywhere—not just in high-resource settings. “It’s easier to ship a pill than an injector,” Thomas points out, highlighting how drug design choices impact global access.

Ultimately, the vision is clear: to use AI not just to invent new medicines, but to get them to patients faster, more equitably, and more effectively.

A Human-Centered AI Revolution

Eli Lilly’s AI journey reflects the convergence of technology, trust, and human ingenuity. By embedding AI across discovery, development, manufacturing, and delivery, Lilly is redefining what pharmaceutical innovation looks like in the 21st century.

Yet, as Fuchs reminds us, this transformation is not about machines replacing people. It’s about empowering scientists, clinicians, and patients with better tools and faster insights. “Medicines make our lives better for everyone,” he says. “Doing that by writing code is just amazing.”

In a world where healthcare challenges continue to grow, Lilly’s approach offers a hopeful vision: an AI-powered future where innovation is accelerated, outcomes are improved, and access is democratized—bringing the promise of advanced medicine to millions around the globe.

AI Innovation Across Healthcare and Pharma

Season 6: Episode #182

Podcast with Thomas J. Fuchs,
Chief AI Officer, Eli Lilly and Company

AI Innovation Across Healthcare and Pharma

To receive regular updates 

In this episode, Thomas Fuchs, Chief AI Officer at Eli Lilly, shares his journey from early machine learning research to spearheading transformative AI initiatives across the pharmaceutical value chain. Lilly is running over a thousand AI projects—from drug discovery and development to manufacturing and commercial operations—leveraging innovations like language models for chatbots, computer vision for quality control, and biomarker development.

Thomas emphasizes trust, transparency, and collaboration as critical to AI adoption, supported by AI certification programs for all Lilly technology employees, as well as AI education resources being made available for everyone at Lilly. He also highlights the company’s unique “lab-in-the-loop” setups that generate synthetic data to accelerate innovation.

Thomas shares real-world successes, including AI-assisted drug discovery and intelligent chatbots, and how AI is building confidence across the organization. With robust data infrastructure and scalable strategies for synthesizing large datasets, Lilly is driving rapid innovation. Thomas predicts faster drug design, broader access to medicines, and continuous education as defining trends for AI in healthcare. Take a listen.

Video Podcast and Extracts

About Our Guest

Thomas J. Fuchs, Dr.sc., joined Eli Lilly and Company as its first chief AI officer in 2024. In this role, Fuchs provides vision, strategic direction and overall leadership of AI initiatives across Lilly, including drug discovery, clinical trials, manufacturing, commercial activities and internal functions. He also identifies, builds and manages AI and machine learning solutions to help Lilly provide medicines to patients around the world.

Before Lilly, Fuchs was dean and inaugural department chair for AI and Human Health at Mount Sinai, director of the Hasso Plattner Institute for Digital Health at Mount Sinai, and endowed Barbara T. Murphy professor for AI and computational pathology at the Icahn School of Medicine at Mount Sinai. Prior, Fuchs held positions at Memorial Sloan Kettering Cancer Center, NASA's Jet Propulsion Laboratory and the California Institute of Technology. He also founded three companies, including Paige AI. Fuchs holds a doctoral degree in machine learning from ETH Zurich and a master’s degree in technical mathematics from Graz Technical University in Austria.


Ritu: Hi Thomas. We are delighted to have you as our guest today on The Big Unlock podcast. This is season six, and we are at about 180 episodes. Our listeners love to hear from people at the forefront of AI who are using it successfully in their organizations. My name is Ritu M. Uberoy, and I’m Managing Partner at BigRio and Damo Consulting, and co-host of The Big Unlock podcast with Rohit. With that, I’ll hand it over to Rohit, and then you can get started. Thank you.

Rohit: Hi Thomas, a very warm welcome to the podcast. We are looking forward to an exciting conversation. I’m Rohit Mahajan, CEO and Managing Partner at BigRio and Damo Consulting. Over to you, Thomas, for your introduction.

Thomas: Thank you so much for having me. It’s a pleasure to be with you. I’ve seen many of your episodes—it’s a great podcast. I’m looking forward to the conversation. I serve as Chief AI Officer at Eli Lilly and Company, a great place to develop AI, build medicines with AI, and help the pharmaceutical value chain deliver more medicines to patients.
My background is in AI. I have a PhD in machine learning from a time when it was not cool yet, and I’ve spent nearly my whole career in AI in healthcare at large systems like Memorial Sloan Kettering and Mount Sinai. I’ve had many students and founded three startups, some of which received FDA approval for AI in healthcare. I’m really excited to be here.

Ritu: Wow. Our listeners always love the origin story. So what pulled you to healthcare specifically, Thomas? You said you were in machine learning, but why did you choose healthcare? That always uncovers a very good journey, if I may say so.

Thomas: Very good question. As a kid, my father took me to a rescreening of 2001: A Space Odyssey, and then I wanted to build AI—like HAL 9000, but a good one. When I did my master’s thesis, I had a colleague who trained a neural network to differentiate cancer from non-cancer. I was completely surprised it was even possible. It was amazing that you can do that with code and help patients. It took over 20 years to get that into the clinic, but being able to help people by writing code is amazing. That got me hooked and that’s why I spend my career and energy in machine learning and healthcare.

Ritu: Great answer. Thank you so much. Rohit, would you like to ask the next question?

Rohit: Thomas, you have a unique perspective having worked in startups and having become familiar with AI before the ChatGPT movement, where AI has been democratized and is within reach of everyone. Please tell us more about your role at Lilly and the initiatives you’re focusing on. We’d love to learn more about what you’re setting out to do.

Thomas: Lilly is a fascinating place because, in contrast to many startups or other organizations, the breadth of AI application is enormous. We use AI in drug discovery for small molecules, large molecules, and genetic medicines. We use it in development, large language models to help draft documents for regulatory agencies or answer questions, and to improve workflows across the organization.

There’s also a huge space in manufacturing. There’s a lot you can do with AI and digital twins to produce medicines better and faster. We use time-based models in financial forecasting for profit centers and P&L, and on the commercial side, we use AI to help our sales force contact HCPs and plan routes.

It’s very diverse throughout Lilly where AI can be applied. We have a central registry tracking all AI projects, currently over a thousand across different areas, making it a very interesting and diverse job.

Ritu: Great answer, Thomas. You know, that leads us into the next question. Last year when we were at HIMSS or any of the other conferences, the main keyword was human in the loop. You know, AI is here to augment, not automate. There was a clear distinction that this is going to be a tool that helps you in your work or makes you do things in a better, easier, or faster way.
But now, with the rise of agentic AI and frameworks, we are seeing complete autonomy. The talk of human in the loop is kind of taking a backseat, and we’re seeing that these agents can autonomously accomplish a lot of work. But with that comes the trust factor. Since you said the range of applications is so broad across Lilly, how do you see that?
How are you evangelizing AI at Lilly to help pathologists, physicians, data scientists, and others trust AI and make sure it’s there to help them in their work and augment human capabilities?

Thomas: Very good question, thank you. And of course, a very broad one. First of all, I think it helps to ground the conversation a little bit. These AI models are all fabulous machine learning models and help us tremendously, yes, but there’s no magic behind them. These models don’t have will or volition, and they’re not going to run off and destroy civilization.

Regarding agentic AI, we use agentic approaches in many areas. We use agentic orchestration, for example, in lab-in-the-loop scenarios or in complicated submission systems. But often, the heavy lifting is not done by the language models used to orchestrate everything, but by dedicated models—for example, diffusion models for molecules or temporal models that we use on the financial side.

There’s a lot of AI outside of language that’s very important, but the orchestration is often done in an agentic way, and the LLMs allow us to have an interface to all of these.

Regarding trust, you are spot on. In organizations like ours, and actually very successful ones, it can be more difficult to have that organizational change management. You have to convince colleagues to use new tools and change what they did in the past. That only works if you are deep in the trenches with the various areas where you apply it. You co-develop with them from the beginning, solve real business or scientific problems, and make sure you can actually integrate them into their workflow.

What never works—didn’t work in healthcare or in startups, and doesn’t work at Lilly—is developing something very cool outside and then trying to throw it over the fence into the application area. That always fails. You have to really do it together, and that builds trust. You also have to have complete transparency and be very clear about the goals—what these things can and cannot do.

Some people think AI is magic and will take over everything, while others fall into the pessimistic camp and think it doesn’t work at all. If you are very clear that these large and powerful statistical models can help many processes and accelerate what we do to get medicines out faster for patients, then you can build that trust and integrate AI systems into daily practice.

Ritu: That’s a great answer. I really agree with you because that’s what we heard at other conferences as well—that it can never be a top-down dictate. It has to be a buy-in from everybody in the company. People have to feel involved, and that makes them more open to being part of the change management.
With that being said, Thomas, if you can give us one or two real-world examples of success stories at Lilly where you’ve had great success with your approach to AI, or demonstrated projects that brought people on board and showed the power of AI, I think our listeners would love to hear more about that.

Thomas: Of course, yes. There are many in the language space. For example, our software product engineering team built something called Cortex, and on top of that, there’s Chat in the Box. These are systems any employee can use. If you have hundreds or thousands of PDFs in your area, you can index them, load them there, and build your own chatbot. We have hundreds of very specialized chatbots in the language areas that people use constantly.
We also have larger, advanced systems with guardrails for communications with regulatory agencies, drafting documents, and so forth.

Outside of language, we have a large initiative in discovery—that’s large molecules, small molecules, nucleotide language models for genetic medicines. For some of our targets, some of the leading molecules were already co-designed with AI. We build our own foundation models at Lilly. We have the luxury of an enormous wealth of data over many decades—Lilly is 150 years old—and reaction data from two decades alone provides a huge resource to build property prediction models and de novo design models. They compare very well with other approaches, which is very motivating for the team.

In the computer vision space, we use vision transformer models or other image-based models for quality control in manufacturing. That has allowed us to increase throughput on production lines for millions of injectors. There you have immediate impact with AI and computer vision. We also use AI to build more biomarkers—where I come from, in pathology—to find and classify cancer, and in the preclinical space to assess disease or reactions to medication in preclinical models. Later, in radiology, we use it to track disease. These are very exciting areas with concrete implications at Lilly.

Ritu: Thank you for sharing some of those examples with us. It’s very interesting, and when you say you have data from 150 years, that’s where most companies get stuck because that data is either isolated or not in a shape or form to be used. So that data scrubbing or data labeling itself becomes a huge project. Did you at Lilly feel the same way, or was the data already in a good enough shape or form to be used or input into your AI systems?

Thomas: Of course, that’s always a moving target for every large organization, but I was surprised how well in shape the data infrastructure actually was when I joined Lilly.

It’s quite amazing. But it is, of course, a moving target. Lilly brings on dozens of new devices every single day, every lab that goes online and so forth. We constantly have new data coming in, new data streaming, and new old data sources being opened up.

So, AI allows us to take advantage of data we couldn’t take advantage of some years back, be it unstructured text data or image data and so forth. It is a constant moving target, and as you know, in machine learning, 80% of your work is always data work, and then 20% is machine learning on top. That does not change at Lilly; it’s like at a startup or in academia as well.

What is very unique here is that we can also produce a lot of data. We have various initiatives where we build lab-in-the-loop setups where we can produce huge amounts of data we can then use to train models at a scale I haven’t seen before. That is very exciting, but it’s also necessary, so you can really compare it to the self-driving car industry where you need your models to produce much more data than you could properly collect in the real world. And that combination of synthetic data and real-world data really gives us the amount of data that facilitates the training of these frontier models internally, which we then can use to design molecules or for all kinds of predictions.

Ritu: That’s a very good insight because I remember hearing about Wabi, who are doing self-driving trucks, and they said there’s just not enough training data in the world to train those trucks, so they had to simulate an entire universe and use synthetic training data to train the self-driving trucks. Those trucks are now driving on the roads of Houston, and it’s really interesting to see how they’ve been trained on synthetic data, but they actually proved that the synthetic data is equivalent. There was no difference between the real-world data and the synthetic data. So that’s a very interesting insight. Thank you for sharing that, Thomas.

Rohit: I was thinking about that, such a large organization with a very large number of employees, Thomas, possibly approaching 50,000 employees globally and many different cultures and languages. Now we have this new thing which is AI and very fast-moving generative AI. How do you win hearts and minds, or how do you influence or turn around such a big ship that you are now suddenly the captain of or steering towards AI? Any initiatives or early steps?

Ritu: With AI literacy, I think Rohit wants to ask how generally?

Thomas: I have to say, first of all, it’s actually easier these days than just a few years back. That’s the change of mind of the whole society. If you think about AI five, ten years back, you had to push ideas very hard to be adopted. For example, in a medical setting, these days, sometimes you have the opposite problem. Again, there’s so much demand that you can hardly fulfill it. In our AI group throughout Lilly, you mentioned the global reach, and I think that’s something very important at an organization like ours. For example, I have great teams in Bangalore, and now we also have teams in Hyderabad, in Ireland, all over the U.S., and many places in the world. That also gives you very diverse ideas about AI, the use of AI across the world from very different societies. That certainly makes our work much stronger, much more robust to all the changes that are happening in our society across the globe. So first of all, that helps a lot.

Second, we do a lot of internal education, of course. At Tech at Lilly, everybody has to be certified in foundation courses in AI. We do advocacy and education for everyone at Lilly. There are a lot of resources we bring to bear. And then we have change champions for AI in all different parts of the organization who not only disseminate knowledge but also get ideas back. With our central AI registry, we are collecting this enormous wealth of ideas throughout the organization. Then we can pick and choose the ones which really drive us forward most and which will help the patients most at the end of the day.

But, of course, since we are in a regulated setting globally, there are a lot of things you cannot easily change. You can run fast and break things and fail a lot, as we do in research, but you cannot do that when you are patient-facing. There, you need quality systems at the highest possible standard in AI as well as in all other spaces. And then, of course, there are regulatory requirements not only from the FDA but also the EMA in Europe, or in South America and Asia, and they all have different AI regulations we have to take into account. So we also have a large initiative on the legal, compliance, and ethics side on how we handle AI throughout Lilly and across these applications.

Ritu: So, for some of the projects that you see, what would be the typical time horizon? Because you said there’s an AI registry and people bring you these ideas. Can you give us a little insight into that? Because you said you like to fail fast and try out ideas. So what are some of the typical timelines for these projects?

Thomas: Of course, it depends, but that’s a very good question. We have a risk-based approach. For example, if you do an internal proof of concept on data that’s not embargoed or doesn’t include PHI, you can be very fast. We often have POCs that take only two weeks—really amazingly fast. I was very surprised when I came in how fast Lilly is moving compared to other areas. But then, of course, if you think about discovery—the development of molecules—these are very difficult things. That takes years, and you need the breadth to develop that and the AI for these models over many years. That also needs expertise of computational biologists or computational chemists who’ve used AI in that field for decades.

So, we set up dedicated teams that dive deeply into these areas. These are not things you can just try out. You can’t throw all your electron microscope data into ChatGPT and hope something comes out. These language models will never solve science on that level. You really need dedicated models, dedicated expertise, and years of work in these different areas. But it’s worthwhile doing that difficult part. And it’s also something I always tell startups. We get so many startups who think they’ll just try something with an API to a language model, make a mock-up in two weeks, and then sell that to pharma. But every startup has to be aware: if it only took them two weeks, then our internal software AI team also only needs two weeks. It’s much more worthwhile to go after the really difficult things—the problems not everybody can solve. And of course, those are the most exciting areas.

Rohit: To that point, Ritu, I’m chiming in – it just sparked a thought around the startup world and innovation in large business enterprises. You’ve seen both, Thomas. You’ve bridged the gap. Would love to hear more about your entrepreneurial journey. What kind of startups you ventured into, how you feel now in a large corporate environment doing innovation, and whether the approaches are different or similar.

Thomas: I had my first startup at 16 in Austria in the nineties. That was a very different world than Lilly is now. Back then, I coded a whole hypertext system without the internet—just from books and magazines. That’s very different from the AI-supported coding we can do today. But it teaches you a lot. One thing that stays constant is that you need, at the end, the customer who’s actually interested and buys what you make, and it has to fit into the workflows you’re developing for.

One of the most interesting startups I founded was called Paige—Pathology Artificial Intelligence Guidance Engine. We spun it out in 2017 from Sloan Kettering. There, we built very large models in pathology. We digitized millions of slides—billions of images, 10 times more pixels than the whole Netflix catalog. With that, we built large frontier models in pathology that led to models for cancer classification in prostate cancer, breast cancer, and so forth. That led to the first breakthrough designation of any AI in oncology from the FDA and the first approval of an AI in pathology. These models work surprisingly well across the globe, so they can generalize.

But in practice, of course, you have hurdles in terms of reimbursement and digitization. Even in the U.S., only 10% of hospitals are digital in pathology. In the other 90%, diagnostics are done like 150 years ago—pathologists looking through a microscope and making a judgment on a slide instead of having a quantitative readout. There’s a huge gap between what we can do today in AI and diagnostics and what patients actually get access to. As William Gibson said, “The future is already here—it’s just not evenly distributed.” You see that constantly.

One reason for joining Lilly was that we have the enormous opportunity to reach millions of patients. You can have an impact at a much larger scale than before. Many of the drugs we’re developing are for terrible diseases like obesity that affect over a billion people globally. To do something against that and help with AI is, of course, fabulous. The sheer scale is very different than back in the day, but of course, a large organization is also very different from a startup.

Rohit: Tough job. I would say Thomas.

Ritu: But extremely rewarding. We’d like to ask Thomas for some closing comments—where do you think the future is headed? What do you think the next three top trends are going to be, for Lilly or for AI in general? Anything else you’d like to share with our listeners? Thank you, Thomas.

Thomas: That’s a difficult question—predicting the future is always challenging. A big area is de novo design of molecules. This is enormously challenging, but the speed of change there is dramatic. Although some are skeptical because we can’t pump out new medicines with AI the way we can generate poems in language, the sheer scale at which we can now propose new molecules that are synthesizable and have attractive properties is a huge phase change compared to one or two years ago. That will impact how fast we can develop drugs, but more importantly, whether we can find the right drugs for the right targets.

When you start solving that problem, the next challenge becomes development—how to prove these drugs work efficiently. That requires rethinking how we run trials. Some of our submissions have 100,000 pages of documents to regulatory agencies—nobody’s going to read that. The agencies will use AI to read it. So wouldn’t it be better to exchange data and do that faster, to get drugs to patients more quickly, given they’re safe, effective, and equitable? If we can prove that, we can hopefully increase the number of medicines delivered globally.

That’s why there’s also a push for small molecules—it’s easier to ship a pill than an injector, which democratizes access to medicines across the world. To do that effectively, we’re again in manufacturing—you have to do it at scale very efficiently. That’s a huge challenge and includes not only digital twins but also robotics, not always humanoid, but industrial robotics, autonomous mobility on manufacturing floors, and across the world. It’s a very exciting area.

Then, of course, a lot of education—not only for healthcare providers but also for patients globally. Hopefully, we’ll have better mechanisms to get drugs to patients. We should never forget that of the increase in life expectancy over the last 100 years, 20 years of that came from better medicines. It’s medicines that make our lives better, and that’s a worthwhile goal to pursue. Doing that by writing code is just amazing.

Ritu: Thank you, Thomas. Great closing thoughts, and I’m sure that leaves a lot for our listeners to think about.

Rohit: Thank you, Thomas, for such an engaging discussion. We really appreciate it, Thomas. Hopefully, we’ll be back again sometime soon to discuss another topic.

Thomas: Thank you for the invitation and for a very engaging conversation. It was fabulous.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]    

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

From Reactive to Proactive Care with AI in Healthcare

From Reactive to Proactive Care with AI in Healthcare

From Reactive to Proactive Care with AI in Healthcare

In a recent episode of The Big Unlock podcast, Dr. Girish N. Nadkarni – Fishberg Professor of Medicine, Chair of the Windreich Department of Artificial Intelligence and Human Health, and Chief AI Officer of the Mount Sinai Health System — offered a clear, pragmatic perspective on how technology can reshape clinical care. Drawing on clinical practice, research, and operational leadership, Dr. Nadkarni emphasized that the real promise of digital health is not novelty for novelty’s sake, but the ability to scale medical knowledge and buy clinicians time to make better decisions.

From Clinician to AI Leader

Dr. Nadkarni’s professional background informs his practical outlook. A trained internist and nephrologist who still spends roughly 25 percent of his time in patient care, he described how his clinical work and academic research intersect in a health system that uniquely integrates its medical school and clinical operations. That integration, he explained, creates a virtuous cycle: clinical problems inspire research questions, and academic breakthroughs can be translated, deployed, and scaled across the system. This operating model gives his perspectives an operational realism that is often missing in more theoretical discussions about AI.

AI as an “Arbitrage of Knowledge for Time”

One of the episode’s most resonant themes was Dr. Nadkarni’s description of AI as an “arbitrage of knowledge for time.” He used concrete examples to unpack this idea. Ambient AI scribes, for instance, transcribe clinical conversations and generate structured notes that clinicians can review and sign. What previously consumed ten minutes per patient for documentation can be reduced to a matter of seconds — Dr. Nadkarni cited a shift from about ten minutes to roughly 30 seconds to finalize notes. That regained time is not trivial: it removes after-hours clerical burden, improves clinician well-being, and returns face-to-face time to patients.

Another application moves care from reactive to proactive. Dr. Nadkarni described a deterioration model deployed in production that predicts patient decline an hour before it happens. That early warning allows teams to intervene — adjusting fluids, antibiotics, or other treatments — potentially averting serious deterioration. Similarly, in the neonatal intensive care unit, vision-based AI systems can continuously monitor infants and flag signs of impending illness well before clinical deterioration. In these cases, the system provides a crucial window of time for lifesaving interventions: that is the practical meaning of arbitraging knowledge for time.

Trust, Scale, and the Double-edged Nature of Technology

Dr. Nadkarni was careful to balance enthusiasm with caution. He stressed that healthcare is a trust-sensitive industry: “trust between a provider and a patient… is paramount.” Scale multiplies both benefits and risks. “If goodness can scale, badness can scale as well,” he warned. A well-intentioned model that contains bias or is applied without contextual safeguards can propagate harm at scale. He used an illustrative example: an algorithm predicting which patients might not show up for clinic appointments could, if misapplied, lead to cancelling appointments for patients who most need care — often the very people experiencing social barriers to access. The right response, he argued, is to address unmet social needs (transport, financial assistance) rather than withdraw services.

To mitigate such risks, Dr. Nadkarni outlined governance mechanisms: an assurance lab to monitor models and a REP (Risk, Ethics, and Policy) committee to evaluate applications. He argued that prototyping and scaling are valid ambitions only if paired with rigor, evidence, and thoughtful governance — a framework that ensures AI systems are safe, effective, responsible, and ethical.

Predictive AI Versus Generative AI: Different Characters, Different Guards

The podcast highlighted the distinction between predictive AI and newer generative models. Predictive models tend to be deterministic and repeatable: the same input yields the same output, which lends itself to reproducible evaluation and monitoring for drift and bias over time. Generative models and large language models, by contrast, are more flexible and non-deterministic; their outputs can vary and require broader evaluation against ethical principles and guardrails.

Dr. Nadkarni described this contrast metaphorically as akin to “left and right sides of the brain” — one logical and structured, the other creative and non-linear. For institutions, the implication is that evaluation and governance strategies must be tailored to the technology class. Both model types require monitoring, but the methods and metrics differ.

Operationalizing AI: Teams, Governance, and Multidimensional ROI

Operational readiness is a recurring theme for leaders trying to move from pilots to scale. Dr. Nadkarni emphasized the importance of cross-functional and multidimensional teams that blend clinical domain expertise with technical capability. Effective AI teams include clinicians or allied professionals who understand the problem, MLOps or AI-ops engineers who build scalable models, research scientists who explore novel approaches, and ethicists who assess risk and fairness.

His description of Mount Sinai’s governance architecture is instructive: AI applications are grouped into domains — clinical care, operations, workforce, research, and students — and supported by an assurance function and a REP committee. This structure enables domain-specific workflows while maintaining centralized oversight.

On prioritization, Mount Sinai requires submissions of ideas from across the health system and aligns them against a 12–24 month set of strategic priorities. Projects are evaluated not only for financial return but for workforce impact, patient experience, and other non-monetary dimensions. This “360-degree” ROI approach ensures that success metrics include provider satisfaction, patient outcomes, and adherence to ethical milestones — with remediation plans if KPIs fall short.

Where Next: Multimodal Integration and Augmentation

Dr. Nadkarni expects the next wave to be multimodal AI – systems that combine text, voice, image, and sensor data. Medicine is inherently multimodal — clinicians integrate visual inspection, conversation, and subtle behavioral cues when making judgments — and AI will need to mirror that complexity. He cautioned that progress will be incremental and that augmentation, not replacement, is the likely near-term path. “In the short term… it’s about augmentation rather than replacement,” he said, underscoring both the potential and the limitations of current systems.

In addition, leaders should prioritize transparency with patients and staff, obtain informed consent, clearly explain how AI-generated notes and alerts are used, and provide clinicians straightforward ways to review and correct machine outputs. Transparency builds trust and smooths adoption. Health systems must invest in continuous monitoring and learning loops so models improve over time and minimize drift or unexpected bias. Training programs to help clinicians interpret AI outputs and to act on recommendations will accelerate practical adoption. These operational investments — governance, monitoring, education, and workflow redesign — are essential complements to any technical innovation.

Practical Implications for Clinicians and Health Leaders

For clinicians and executives contemplating AI adoption, the episode offers several actionable takeaways. First, focus on problems that buy time or reduce friction — documentation automation and early warning systems are tangible, high-impact examples. Second, build multidisciplinary teams and governance processes before scaling. Third, adopt multidimensional ROI frameworks to capture patient and workforce effects, not just cost savings. Fourth, prioritize transparency and training so clinicians understand AI outputs and patients are informed about how data are used. Finally, monitor models continuously to detect drift, bias, and unintended consequences.

Dr. Nadkarni’s mantra — that AI is an “arbitrage of knowledge for time” — reframes technology as a time-saving, decision-enabling tool rather than a pure technical curiosity. By combining clinical insight, disciplined governance, and a patient-centered ROI lens, organizations can harness AI to shift care from reactive to proactive — while safeguarding trust and equity at scale.

AI in Healthcare is an Arbitrage of Knowledge for Time

Season 6: Episode #181

Podcast with Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System

AI in Healthcare is an Arbitrage of Knowledge for Time

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In this episode, Dr. Girish N. Nadkarni, Chief AI Officer at Mount Sinai Health System, discusses his background as a physician-technologist and his vision for AI in healthcare as a tool that augments rather than replaces clinicians.

Dr. Nadkarni shares insights on how AI is reshaping healthcare. He describes AI as an ‘arbitrage of knowledge for time,’ enabling physicians to spend less time on administrative work and more time with patients. He also shares real-world examples including ambient AI scribes that eliminate manual note-taking and predictive models that detect patient deterioration hours before it occurs, especially in critical care units such as the NICU. Dr. Nadkarni distinguishes predictive AI’s deterministic approach from generative AI’s flexible, non-linear potential, emphasizing the need for governance, ethics, and trust in deploying both. He outlines Mount Sinai’s cross-functional framework—spanning care, operations, workforce, and research—supported by an assurance lab to monitor bias and safety.

Dr. Nadkarni highlights current AI applications that save physicians time and enable proactive care, while predicting future developments will include multimodal integration of text, voice, images, and video to better reflect clinical decision-making processes. Take a listen.

Video Podcast and Extracts

About Our Guest

Dr. Girish N. Nadkarni is the Fishberg Professor of Medicine, Chair of the Windreich Department of Artificial Intelligence and Human Health, and Chief AI Officer of the Mount Sinai Health System. A physician-scientist and clinical informaticist, he leads transformative AI research in cardiovascular and kidney care, including the first FDA-approved AI-bioprognostic for kidney disease. He has over 460 publications, 40,000 citations, and an h-index of 93. As PI on ~$40M in grants and contracts, he also co-founded multiple FDA-cleared AI startups. Dr. Nadkarni serves nationally in AI leadership and mentors future faculty leaders, earning numerous awards for research and innovation.


Rohit: Hi Girish. Welcome to The Big Unlock podcast. Really wonderful to have you here.

Girish: Hi Rohit, hi Ritu. Thanks for having me. It’s a pleasure.

Ritu: Welcome, Dr. Girish. We have a lot of episodes—175 and counting. Listeners are always in for a treat, and they enjoy hearing new perspectives on AI. Every physician has such different thoughts about AI, how they got here, and what they think future trends will be. So, I’m looking forward to an engaging and interesting discussion. Welcome once again.

Rohit: Thank you. I’m Rohit Mahajan, Managing Partner and CEO at Damo Consulting and BigRio.

Ritu: I’m Ritu M. Uberoy, currently based in Gurugram, India. Also, a Managing Partner at BigRio and Damo Consulting, and co-host of The Big Unlock podcast with Rohit. Looking forward to our discussion today. We’d love to start with your introduction.

Girish: Thanks, Ritu and Rohit. My name is Girish Nadkarni. I am the Chair of the Windreich Department of Artificial Intelligence at the Mount Sinai Health System. The department is the first of its kind in the country, established within a health system and medical school.

I’m also the Director of the Hasso Plattner Institute for Digital Health at Mount Sinai. Those are my academic roles. In addition, I serve as the Chief AI Officer for the health system. Clinically, I’m an internist and nephrologist, and I still actively see patients about 25% of my time—both in outpatient settings and on the clinical floors.

Most of my time is spent doing research, but more importantly, translating, deploying, and scaling that research into clinical care and operations.

I grew up in Bombay, India, which some of you may know is one of the largest cities in the country. I live in New York City now, but the scale of Bombay—or Mumbai—can put New York City to shame, just in terms of the number of people.

I went to medical school in India. From a young age, I was interested in tech and computer science. As you both know, in India you typically either go into engineering or medicine. My parents made it clear: you’re either a doctor or an engineer—or you’re a failure. Both of my parents were doctors, and although I cleared the engineering entrance exam, I was drawn to medicine.

Medicine is a noble profession. What’s more noble than helping and healing people when they’re most vulnerable? More importantly, I was interested in prevention—helping people before they became that sick.

During medical school in India, I always wanted to further my training in the United States because it has led the world in innovation at the intersection of medicine and technology. I came to the U.S., completed a master’s degree and postdoctoral fellowship at Johns Hopkins, and since 2009 I’ve been in New York City.

I did my residency, fellowship, research, operational training, and faculty roles all at Mount Sinai. The health system is unique because it combines a medical school and a health system, which creates a free-flowing exchange between academic discoveries and clinical operations. Research can be translated and scaled across the system, while clinical practice inspires new basic research questions.

I feel fortunate to be in this role. Healthcare is a field where change is often imposed externally—by policies or new technology—but meaningful change must also come from within. If clinicians broadly—physicians, nurses, and other health professionals—become true evangelists for responsible tech, we can create transformative change in healthcare like never before.

Ritu: That’s a great introduction. Thank you so much, Girish. I’m really curious—right now with AI and the rapid pace of change, especially with LLMs, we’re hearing about a lot of physicians and clinicians getting into tech. But your interest in tech predated all of this. Tell us a little bit about that—how you felt back then versus now.

Today, people feel that AI is so enabling. It has democratized access to technology and made it easier for non-tech people, especially clinicians and physicians, to prototype and build things they couldn’t before. Do you feel the same way? Do you think the pace of change has been like light years’ worth?

Girish: I’ve been in this field for the last 15 years, and my interest in tech has always been for medicine’s sake. Technology is one way you can scale impact in ways a single physician—or even a single healthcare system—cannot. Tech can touch millions of lives at scale, which is what drew me to it.

The idea is to take what we know from medicine and codify it into a knowledge base that can then scale across demographics, populations, countries—even globally. That’s the promise of tech.

Yes, things have gotten easier in terms of building and prototyping because of large language models. If you think about what LLMs are, they’re essentially encoded human knowledge at scale. They’ve read all of human knowledge, compressed it, and made it possible to converse with and ask the right questions to get back knowledge at scale.

This democratizes access. Now, if a physician has an idea, they don’t need to rely on a lengthy process to prototype it. They can bring their idea to life as an app or a product and test how it works.

But this also introduces unique challenges. Let me start with a couple of assumptions I hope we all agree on. First, healthcare is an industry where trust is paramount—trust between provider and patient, and trust between the system and the broader social and cultural environment it operates in. We must safeguard that trust.

Second, while scale is useful, it has a flip side. If goodness can scale, badness can scale too. A useful, effective product can scale—but so can mistakes or bias. That’s why it’s essential to be rigorous, responsible, and trustworthy in healthcare. This is a trust-sensitive, patient-centric industry, and we cannot allow mistakes or bias to scale unchecked.

So yes, prototyping and scaling make sense—but they must be backed by rigor, good governance, and solid evidence.

Ritu: Great. That’s what we’ve been hearing across the board—it comes with its own baggage, and you have to be really careful to, as you said, have rigor, responsibility, and trust, which are paramount. Great answer, thank you. Rohit, would you like to ask a question?

Rohit: Yeah, Girish. Could you tell us a little more about your AI journey, or share examples you’ve seen that have positively impacted patients—something we could talk about today?

Girish: Oh, absolutely. I can talk about the broader AI landscape in healthcare right now. I think healthcare is at a transition point. The U.S. healthcare system costs a lot of money and is focused predominantly on sick care rather than healthcare. We wait for people to get sick, then we treat the sickness. The financial incentives are also aligned that way—and that needs to change.

The promise of AI, in my view, is that it’s an “arbitrage of knowledge for time.” What I mean is that because knowledge is compressed and encoded, you can use it to buy time for making decisions.

A great example in healthcare is ambient scribes. As a physician, suppose I have a 20-minute patient visit. In practice, I spend 10 minutes talking to and examining the patient, then another 10 minutes typing up my note. Alternatively, I could spend the full 20 minutes with the patient—but then I’d have to go home after putting my kids to bed and finish my notes.

Ambient AI scribes flip that paradigm. During a natural clinical conversation with a patient, you don’t have to type into the computer. The entire interaction is transcribed into a structured note. All you have to do is review it for accuracy and sign off. What used to take 10 minutes per patient now takes 30 seconds. That’s what I mean by arbitraging knowledge for time—you gain time back with every patient and avoid doing data entry after hours.

Another example: imagine if you knew a patient was going to deteriorate in the hospital one or two hours before it happened. That time would allow you to make a life-saving intervention. That’s another way AI arbitrages knowledge for time—by shifting care from reactive to proactive.

We developed a deterioration model that predicts if a patient is going to get sick an hour in advance. It allows clinicians to intervene, maybe give IV fluids or switch antibiotics, before the patient worsens. That model is already in production.

A second example, very close to my heart, is in the neonatal intensive care unit, where premature babies are often the sickest patients in the hospital. Using vision AI—similar to the technology in self-driving cars—we can continuously monitor babies and predict an hour in advance if one is going to get sick. That gives care teams time to act and potentially prevent deterioration.

So again, I like to say AI in healthcare is an arbitrage of knowledge for time. It gives providers time to make critical decisions and also gives them back time in their day that would otherwise be lost to data entry and processing tasks.

Ritu: Amazing. This neonatal ICU example is incredible. I can only imagine how many babies’ lives have been positively impacted. That’s a wonderful story—thank you for sharing, Girish.

Rohit: Girish, I think we were talking the other day about traditional AI and the new AI—generative AI and large language models. How do you distinguish between the two in your team? And how do you build teams for AI work, since these tasks often require cross-functional expertise—problem definition, technical skills, and domain knowledge? How do you structure that at your organization?

Girish: That’s a big question, but I’ll try to answer it in parts. AI has been used in medicine for a while now, but most of it has been predictive AI. It’s been, “Given this set of data, what is the probability that something good or bad will happen to the patient in a certain amount of time?”

The difference between that and generative AI is that predictive AI is usually deterministic. If you enter the same set of features, you’ll get the same answer every time—it’s very repeatable. New AI, on the other hand, is much more flexible and non-deterministic. You can get different answers to the same question depending on context.

It’s almost like the left and right sides of the brain. Predictive AI is extremely logical, follows a process, and arrives at an answer. Generative AI is more creative and non-linear. Both have to be governed differently, and the way you evaluate them is also different.

With predictive AI, you focus on making sure it isn’t biased against certain populations, and that when you deploy and monitor it over time there’s no drift—meaning the model doesn’t degrade as the underlying data changes. Generative AI requires a more holistic evaluation. You have to ensure it aligns with a broader set of ethics and values, and put guardrails in place so it doesn’t deviate from them.

We’re setting up what we call an “assurance lab” to monitor both predictive and generative AI in different ways, but with the same underlying goal: AI must be safe, effective, responsible, and ethical.

And for that, you need cross-functional teams. You need someone who understands the clinical problem—that could be a doctor, nurse, medical assistant, or allied professional. Then you need someone who can build AI models at scale, usually an MLOps or AIOps engineer. You also need researchers, because sometimes you need people to think outside the box and explore different solutions. Finally, you need a layer of ethics—people who understand the risks and ensure the work is responsible.

We’ve set up a governance structure that combines all digital and AI applications, divided by domain. There’s an AI care domain focused on clinical care; an AI operations domain for back-office operations, finance, and regulatory; an AI workforce domain for workforce applications; a research domain; and a student domain. All of these are underpinned by the assurance lab and by the REP—Risk, Ethics, and Policy—committee.

Why is this important? Because even if an algorithm is pristine, its application can have issues. For example, you could have an algorithm to predict which patients won’t show up for clinic appointments. But if applied incorrectly, you might cancel the appointments of the very patients who most need care. Often, patients who miss appointments have unmet social needs. The right solution isn’t to cancel on them—it’s to address those needs, like providing transportation or financial support.

So yes, you need cross-functional and multidimensional teams to tackle clinical, operational, or workforce problems. But everything must run through governance to ensure the work is safe, effective, responsible, and ethical.

Rohit: That’s great to know. And when you look at these applications, do you have some kind of framework or success metrics—what people often call return on investment? How do you go about prioritizing projects, especially now that so many physicians are becoming interested and more ideas are coming your way as Chief AI Officer?

Girish: Yes. We have a process where anyone in the health system can submit an AI or digital idea. I work closely with the Chief Digital Transformation Officer, Robbie Freeman, and our Chief Digital Officer, Lisa Stump, on this.

First, as a health system and academic institution, we define a list of clinical and operational priorities for the next 12–24 months. Part of the process is aligning ideas to those priorities. If an idea aligns with strategic priorities, it gets higher prioritization and faster execution.

Second, every idea must go through governance, as I described earlier, to ensure it is safe, effective, ethical, and responsible—not only in development, but also in execution.

Third, we calculate ROI for all priority projects. But this is a multidimensional ROI—it’s not just financial. We also consider workforce impact and patient experience impact. It’s a holistic, 360-degree evaluation.

We also monitor projects over time to ensure they meet predefined milestones. For example, with an ambient AI project, one milestone might be provider satisfaction. How many providers are satisfied with it? We track KPIs, and if a milestone isn’t met, we require an explanation and a remediation plan.

This way, we ensure ROI is not just about finances—it’s about employee experience, broadly defined, and patient experience as well.

Rohit: And one tough problem I’ve seen before—and something the C-suite often struggles with—is where the money comes from. If you’re focused on cost savings, you might say, “We’re going to save costs by becoming more efficient.” That’s one way to look at it. But how do you think about budgeting for AI? Is it longer-term or shorter-term? Any high-level perspective you can share?

Girish: If you align your roadmap—your operational map—with the larger strategic priorities, then you automatically get C-suite buy-in. These are priorities already set by leadership, and we’re just enabling and accelerating them. That also makes it easier because budgets have already been allocated for those priorities.

And honestly, the cost of generating software has gone down significantly. You know this better than me—the cost of coding agents and developing software is far lower than it used to be. So if incentives, strategic priorities, and broader vision are aligned, the more tactical, lower-scale items start to align as well.

Rohit: That’s great to know.

Ritu: So Girish, you mentioned “ambient” a couple of times, and we all know that’s been one of the big success stories across hospitals and health systems. Our listeners always want to hear what’s coming next—straight from our guests. In terms of trends, what do you think will be the next big win for AI? Where is it headed in the next 6–12 months?

Girish: In the next 12 months, I think we’ll see much more multimodal integration, which is especially relevant in medicine. Right now, most AI is text-based. But that’s not how clinical decisions are made. Clinical decisions involve talking to the patient, observing them, noting how they look, how they speak, and even their frame of mind in that moment.

The technology isn’t fully there yet, but I think it will be in the next few years. And I still believe that in the short term—say, the next 10 years—it’s about augmentation rather than replacement. These systems, while powerful, are fragile, and trust is a huge factor. People aren’t ready for a fully autonomous AI doctor.

So I see multimodal integration—combining text, voice, images—becoming more common. We’ll see a push beyond ambient recording, perhaps toward video recording with patient consent, sensors, and more. Broadly, though, I think the shift will be from reactive medicine to proactive medicine, and AI in all its forms will be an enabler of that.

Ritu: Great point. We’ve also been hearing a lot about voice agents and conversational AI, so I think you’ve hit the nail on the head there. Thank you.

Rohit: Thank you, Girish. As we come to the close of the podcast, are there any final thoughts you’d like to share with our listeners?

Girish: I’d just say this: AI is a very impressive technology. For the first time in human history, it’s approaching cognition, which until now was the preserve of humans. We should think of AI as a collaborator, not a replacement—something that helps us become the best version of ourselves.

At the same time, we shouldn’t wear blinders and assume it’s flawless. We need honest assessments, constant monitoring, and recognition of its flaws. There’s hope, and yes, there’s hype, but it should always be tempered by reality and rigor.

Rohit: That’s a great closing thought. Thank you so much, Girish. We really appreciate your time.

Ritu: It was wonderful having you on the show. Thank you for joining us.

Girish: Thank you both. It was a pleasure.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI, Design, and the Future of Operational Workflows in Unlocking Healthcare Efficiency

Season 6: Episode #180

Podcast with Michael Docktor, MD,
Co-founder and CEO of Dock Health

AI, Design, and the Future of Operational Workflows in Unlocking Healthcare Efficiency

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In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children’s Hospital to building a healthcare technology company. Inspired by his sister’s medical experiences and his family’s design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff.

Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes.

The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health’s “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the “big unlock” that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.

Video Podcast and Extracts

About Our Guest

Michael Docktor, MD, is the co-founder and CEO of Dock Health, the first AI-powered productivity platform purpose-built to solve healthcare’s operational challenges — from referral management to task automation and workflow orchestration. A practicing pediatric gastroenterologist at Boston Children’s Hospital, Docktor previously served as the hospital’s clinical director of innovation and director of clinical mobile solutions.

With nearly two decades of experience at the intersection of clinical care and digital transformation, he is focused on bringing clarity, accountability, and efficiency to the work behind care.


Q: Hi, Dr. Michael Docktor, welcome to our Big Unlock podcast. We are really happy to have you as a guest on our show. Uh, it’s on our sixth season now, and, uh, we are looking forward to this conversation. I’m sure we’ll have a very engaging and interesting conversation about dog health, about healthcare in general, and the new trends about AI and all the buzzwords that people want to hear. Welcome to our show — we’d like to start with introductions. Happy to have you give your introduction. Thank you.

Michael: Yeah, thank you so much for having me. Yeah, I’m Michael Docktor, co-founder and CEO of Dock Health. I’m an ologist by trade. I am now on this, uh, healthcare venture outside of Boston Children’s Hospital where I started my GI career.

I was a busy clinician working on the clinical side as well as in innovation and informatics, and found that we had wonderful tools in the world outside of healthcare and struggled with my own challenges around managing all the tasks that are part of patient care. I found that I was using task management and project management tools that were not built for healthcare.

I scratched my head and wondered why we don’t have these things for healthcare. That was a journey. We started just over five years ago. We spun out Dock Health from Boston Children’s, and we’ve been on a very exciting journey in the world outside the academic walls since then.

It’s been fun. I’m excited to talk to you more about, uh, what we’re doing.

Q Great. That’s a great introduction. Thank you for letting our listeners know. We usually like to start with how you came into healthcare because everyone has an interesting story about what inspired them to become a physician.

For you, it’s particularly interesting because you’ve created this interface between design, technology, and healthcare — and you went beyond just visualizing what you wanted to do or asking why somebody doesn’t fix it, to actually building it yourself. I’d love to hear more about how you came into medicine and then into technology.

Michael: I could probably spend the entire podcast on this question. Obviously, my last name is Doctor, so there was some planting occurring there, and there’s something to be said for that.

One of my earliest memories was wanting to grow up to be a doctor. My younger sister had some GI issues when we were young, and I became very close with her gastroenterologist. I followed her on her journey and, unbeknownst to me, ended up following one of my mentors and was inspired to do the work for other children the way my sister was cared for. That was the initial inspiration.

You mentioned design. That’s interesting because my mother is an interior designer, my father is a dentist who specialized in aesthetics, and design — how things look, feel, and work — has always been part of my DNA. It was an amazing journey to go from being a traditional doctor in pediatric gastroenterology to discovering the importance of user experience and user interface.

Then the iPhone came out, then the iPad, and that really started me on my journey of exploring app development and software, and wondering why we didn’t use these wonderful devices in our pockets the way we should. That journey started more than 10 years ago and has led me to this perfect intersection of healthcare, design, and informatics, creating better experiences for patients and providers.

There’s a lot to unpack there, but people ask me if I would do it differently if I had the chance to do it all over — and absolutely not. I’m doing exactly what I want to be doing right now.

Q: Thank you for sharing that. That gives us so much perspective into how you came into this field, the influence of your parents, and how everyone around you inspired you to do this. That’s really interesting.

That leads us into how you built Dock Health. Tell us some examples of how you saw this becoming transformational in actual implementations with clients. When you built the tool, did you visualize exactly what it would do? Did it go beyond what you thought it would achieve in a healthcare setting? We’d love to hear more about that.

Michael: We’re far beyond where I ever thought we’d be when we first started this journey. That’s the exciting part. Fundamentally, we have such an administrative and operational challenge in healthcare. I saw it firsthand as a busy clinician struggling to manage all the clinically adjacent work that had to be done for my patients.

For example, I might have a patient with Crohn’s disease who needs to go to an infusion center. There are all these downstream tasks and administrative steps that need to be done by a team of people. We didn’t have assistants to do that, and the electronic health record wasn’t built for it.

A quarter of the $5 trillion spent in healthcare goes to administrative and operational challenges, and there really are no tools built for that. We rely on paper checklists, email, faxes, and spreadsheets to manage all the work happening outside the electronic health record.

For me, the realization was that I was using wonderful project management and task management tools to run software projects in my innovation and informatics roles—and yet nothing like that existed in healthcare. Patients, in many ways, are projects. There are tasks that form the essence of care, and they need to be tackled, managed, and collaborated on, with visibility and accountability across teams. That didn’t exist.

What we are now doing is serving as that productivity platform for healthcare, one that sits alongside the electronic health record in synergy, helping manage all the administrative and operational tasks of patient care in ways the EHR wasn’t designed for.

Some examples would be managing patient intake and all the processes associated with it. Referrals, inbound and outbound, with all the paperwork, eligibility checks, and faxes—those workflows are still incredibly manual. Referrals are a great example: 80% of referrals that come into major academic medical centers are still arriving by fax, despite the fact that they’re using Epic, a wonderful electronic health record.

These processes are still incredibly laborious, take too long, and are inefficient. Patient care suffers along the way. There’s a gigantic bottleneck around the administrative and operational work that moves patients through their journeys, and that’s what we’re focused on fixing.

Q: This is what we hear from a lot of our clients and other CIOs and C-suite leaders who come to our podcast—that this is one major problem with healthcare. It’s siloed, and the processes are really stuck in the dark ages.

We were talking to somebody from Athena, and they said they had an 800-person offshore center in India just to screen faxes. When a fax came in, one person looked at it to see if it was a pizza order or a referral. It sounds unbelievable in this day and age, but that’s how it works. I’m amazed to hear this from you as well. It’s remarkable.

Michael: Yeah. In fact, Athena is a partner of ours, and we’re working on referral management. It’s an incredibly antiquated process where everyone loses visibility. The amount of manual labor required to process these things is shocking in this day and age, when they can be handled through process automation, AI, and agents.

Q: Exactly. You’re talking about agentic, we’re talking about voice agents, and yet we’re still dealing with faxes. That’s really interesting to know.

Michael: There is reason to be hopeful. Healthcare is always many decades behind, but the adoption of AI is progressing more rapidly than I’ve seen any technology adopted in healthcare. There’s reason for hope.

Q: That leads into my next question, but before we get there, you mentioned Dock Health as a productivity platform. That’s what it does for doctors, clinicians, and patients. But when we talk to our doctors, clients, and health systems, the one word that always comes up is complexity. They deal with so many different systems and have to learn something new each time.

Where does Dock Health fit in? Is it another system they have to manage, or does it help reduce that burden?

Michael: Yeah, it’s all about reducing the burden and improving the user experience. That’s been fundamental to our belief system since the founding of the company.

First and foremost, we’re trying to become the productivity platform and the hub that handles the administrative and operational work. Instead of being “another system,” we’re often replacing spreadsheets, paper checklists, emails, and faxes—the ways we’ve traditionally managed the 50% or more of administrative and operational tasks required for patient care.

The EHR is great for clinical work, billing, prescribing, and scheduling, but so much happens downstream that isn’t covered. I’d argue we are creating the hub for that. Just as the EHR is the clinical hub, Dock Health serves as the operational hub. Together, it’s really one plus one equals three.

We’re also aiming to be much more consumer-like in our approach. Our tool can onboard a customer in 30 minutes. We offer a free trial, and for small organizations that want to get up and running, they can start using it right away—just like downloading an app. It’s lightweight, highly configurable for end users, and designed with a strong focus on user experience.

The real challenge is that clinicians don’t want another tool. They’re busy and need to spend their time in the EHR. Our core users are often the super users: front office staff, back office teams, operational leaders, and administrative staff who leverage our tool every day.

The important piece is that we connect to the electronic health record and provide visibility for clinicians. If they’re interested, they can see where a patient is in their journey or where a process stands, but they don’t have to be in our system all day, checking tasks or learning another workflow.

The intent is to provide that operational hub for administrative and support staff—the essential members of the care team—while clinicians continue their work in the EHR and often drive tasks into our system through their orders and actions there.

Q: Is the integration with the EHRs native, like with Epic, Cerner, and the big ones?

Michael: Yeah. We’re on the marketplace with a number of the top EHRs, including Epic and Cerner. We’re also working with Mayo Clinic, their Mayo Clinic Platform, and their Deploy platform.

The other thing I’d mention is that many organizations use our tools without being integrated with the electronic health record. That’s often because they’re smaller practices—mental health, concierge care, or primary care—that simply need a hub to handle administrative and operational work and collaborate as a team.

We spend a lot of time helping organizations define their processes, and those processes can then live in Dock, where they can be collaborated on and turned into operational best practices. That’s something that often doesn’t happen in traditional healthcare organizations, and our tool is valuable even when it’s not connected to an EHR.

Of course, the real value comes when we integrate with systems—EHRs, CRMs, patient engagement tools—and serve as the hub while automating as many tasks as possible. That’s when the flywheel starts turning, and organizations begin to feel the benefits of automation and work reduction. It ultimately moves the needle in a measurable way.

Q: So, you’re saying if there’s an integration with the EHR, then it’s end-to-end and people can see a complete view of what’s happening. But even without the EHR, because it helps with workflow management, it’s valuable for practices?

Michael: It’s just like every other industry. They have Asana, JIRA, Trello—all these tools where a lot of the real work gets done. That provides value in itself by giving a clear view into where the patient is in their journey and what process they’re following.

When we integrate with an EHR or other systems, we can then automate those workflows. For example, when a fax comes in, we can launch a workflow for a new patient referral. When a lab order is placed, we can launch a workflow for follow-up. Or when a patient has a procedure, we can launch a process for their downstream follow-up.

Q: That leads into the next question, which is your learning journey with AI. What advice do you have for our listeners about where AI is headed? And with voice agents and agentic tech being buzzwords, where do you see Dock Health going? Are you also looking at implementing voice agents?

Michael: AI is incredibly exciting. I’ve put it out there that we’re an AI-first company. We’ve been thinking about this for a while, and we already have what we call Dock Intelligence in production with customers. We started with the basics, using foundational models and generative AI to process large troves of data.

Now, we can summarize all the work being done for a patient and create a snapshot for the end user—showing all tasks, workflows, patient context, and even clinical context if available. That gives a quick overview of what’s happening. Users can edit that snapshot if needed, or generate a note that writes back to the EHR to keep the operational and clinical record in sync.

That’s the first step in our AI journey. From there, we realized tasks bundle into workflows, workflows can be automated, and now we’re starting to farm out those tasks to agents and AI. For example, a voice agent could follow up with a patient to confirm a referral or review lab results. We’re actively pursuing that, as well as leveraging AI to extract data from faxes to automate referral processes.

AI is the big unlock. In the next three to five years, I believe most administrative and operational tasks will be handled by automation and AI agents orchestrating together. These agents need rails to run on and structure to guide them, and end users must remain in the loop to provide oversight and visibility. But the lion’s share of this work will be handled by agents—and we’re building that future right now.

Q: Are you aligning specifically with any particular LLM or provider, or are you going to be completely agnostic?

Michael: I’d like to think we’ll be agnostic. We’re doing plenty of building on some of the foundational models ourselves, and we’re partnering where we can with great tools. For example, with voice agents, we’re not necessarily building them ourselves—there are excellent options out there. What we are doing is building our own homegrown AI agents that can manage processes and facilitate handoffs from task to task.

Our approach has always been to recognize that there’s a wonderful ecosystem out there. We want to be the hub that connects to the best-of-breed systems—whether that’s Epic as an EHR, Salesforce as a CRM, or other tools we can leverage to create a healthy ecosystem. That’s what we’re pursuing.

Q: I wanted to ask a question about that because with the LLMs, one of the main problems is the hallucinations or the repeatability or the trust factor there. So I saw that Dock is HITRUST certified. So, I just wanted to ask, what are your views on that? Because in terms of using generative AI when we talk to our clients, uh, for implementations on LLMs, or they’re more comfortable certainly with the administrative tasks, but even with the administrative tasks there’s always the question of what are the guardrails you put around that and how do you make sure that the results that you are seeing or you are displaying on Doc Health, you know, stay within that, those bounds of accuracy. Whathat are your thoughts around that?

Michael: AI is incredibly exciting—it’s moving at the speed of light, and everyone wants to benefit from it. I do think administrative and operational areas of healthcare are lower-hanging fruit and far less risky. We’re not yet in a place where we can reliably use AI for absolute clinical decision support and autonomy, though I believe we’ll get there in the not-too-distant future.

For now, the clunky and manual administrative work is ripe for AI. Still, we need to be mindful of potential hallucinations. In our experience so far, we haven’t seen issues, but we’ve put safeguards in place. That means keeping a human in the loop to ensure outputs are appropriate and relevant. We also give users the ability to edit results before they’re sent—whether it’s a summary being emailed to a colleague or written back into the EHR as a clinical note.

It’s essential to show your work. If we’re pulling data from various sources, we show those sources. We keep users in the loop, give them control to review and edit, and maintain tight feedback loops to catch and address anything off.

So far, even foundational LLMs have been surprisingly strong in our relatively narrow use cases. The real challenges will come as we move toward higher-risk clinical decision support—but I’m confident we’ll get there quickly.

Q: It’s interesting you mentioned humans in the loop and the fact that people can review or edit what’s being generated. But with agents, one of the key defining characteristics is autonomy—they can make API calls, send emails, even browse the web to find and act on information. How do you think about that level of control being handed over?

Michael: I think it’s all about balance. The value of task automation and workflow automation is clear. For us, one of our strengths is providing a user interface where the end user can actually see where a process is in its journey.

We’re working on features like showing confidence levels or confidence intervals for data extracted—for example, from a fax. That way, we not only show our work but also give transparency into how accurate that extraction might be. Using our interface, which breaks workflows into tasks, we can show exactly where a process stands. If we believe human involvement is needed, we assign a task and call someone in to review.

Even in the agentic future—which is already upon us and actively being built and tested—we see ways to keep humans in the loop. Operating entirely in a vacuum is risky. Part of my mantra, coming from clinical practice, is that I lacked visibility and accountability in the work being done on behalf of my patients, lost in a black hole of faxes and emails. It’s important to show where the patient is in their journey, where the process stands, whether an agent is handling it or automation is moving data between systems. Giving people visibility and the ability to drill down is critical.

Q: That’s an interesting viewpoint. You mentioned the front and back office and clinicians, but I didn’t realize patients might also have visibility into the system.

Michael: That’s certainly the vision for the future. Right now, our solution focuses on creating visibility and accountability for the care team—clinical and operational staff. But ultimately, the patient is part of the care team too. I would love to see a future where patients are assigned tasks and the rest of the care team has visibility into their progress. I think that’s inevitable. For now, we’re focused on giving the traditional care team the tools they need, but over time, I see patients and their home-based care team being part of that ecosystem.

Q: So I think we are almost at the end of the podcast. We would like to conclude by asking you what you think, maybe give a horizon of like a year and then maybe a five-year horizon. What do you think the top trends that are going to be in AI, and particularly for you at Dock Health? What are the three things that you are really keeping close tabs on and you feel that it’s going to really impact your product and be very transformational.

Michael: It’s tough to predict because AI is moving so fast. Moore’s Law doesn’t apply anymore—the doubling is happening every few months. Everything right now is AI, and “agentic” is the word of the day. I’ve even heard “ambient agents.” We see our role as orchestrating workflows where agents will carry out the majority of tasks.

When we started Dock Health, I imagined a day when it would be smart enough to handle processes automatically. AI has accelerated that roadmap by five to ten years, and the pace keeps shrinking. I truly believe that in the next five years, when healthcare spending in the U.S. reaches $10 trillion, the $2.2 trillion spent on administrative and operational costs may actually shrink because of operational efficiencies unlocked by AI.

We want to give care teams superpowers. Administrative and operational staff deserve better tools to do their work. Just as ambient scribes are now relieving clinicians from documentation, I believe AI will do the same for the administrative and operational burdens in healthcare. Within three to five years, I expect most of that work will be automated. Humans will still play a role, but much of it will feel like it just happens—almost magically.

If you zoom out five years from now, it will look like magic. But by then it will feel obvious. And that excites me, because at the end of the day, patients, our economy, and the world need more efficient care. The fact that we waste a trillion dollars a year on administrative tasks is shameful. Patients are asked to take on too much, like reminding us about referrals or tracking down lab results. These things happen because we’re human and don’t scale well. But now we have incredible tools at our fingertips, and I believe the next few years will be the most exciting time healthcare has ever experienced.

If we zoom out five years from now, it’s going to look like magic—but by then it will feel obvious. I’m excited for that future because, at the end of the day, patients, our economy, and our world need more efficient care. The fact that we waste a trillion dollars a year on administrative and operational tasks is shameful.

Too much of the burden falls on patients. Physicians and care teams often say, “Call me if you don’t get your referral in a couple of days,” or, as I saw with my own mom recently, patients are left chasing down lab results. These things happen because we’re human and we don’t scale well.

Now, we have incredible tools at our fingertips. That’s why I believe the coming years will be the most exciting time in healthcare that I’ve ever experienced—and likely the most exciting time the world has ever seen. Healthcare is primed for transformation and opportunity.

Q: Thank you for being with us on our podcast. It was a wonderful conversation, and we look forward to sharing your vision for the future with our listeners.

Michael: Thanks so much.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Reducing Clinician Burden and Unlocking Value Through AI

Reducing Clinician Burden and Unlocking Value Through AI

Reducing Clinician Burden and Unlocking Value Through AI

Artificial intelligence in healthcare has rapidly moved from hype to practical implementation. At Hackensack Meridian Health (HMH), one of New Jersey’s largest health systems, AI is no longer a futuristic concept but a daily reality that is reshaping workflows, improving patient experience, and supporting clinicians.

In a recent episode of The Big Unlock podcast, Sameer Sethi, Senior Vice President and Chief AI & Insights Officer at HMH, shared how the organization is embedding AI into its core operations. With a portfolio spanning data and analytics, AI, robotic process automation (RPA), and software development, Sameer and his team are focused on one mission—using AI to create real-world impact.

Moving Beyond Theory: AI in Clinician Workflows

For Sameer, the value of AI lies not in experimental pilots or theoretical discussions, but in embedding technology directly into workflows. “It’s one thing to give someone access to a conversational AI,” he explained. “But the real value is in customizing it for clinicians at the point of care.”

One of HMH’s earliest use cases with large language models was clinical summarization. Traditionally, physicians spend significant time combing through patient records during visits, time that often takes away from patient interaction. By building an AI-powered “summarize” button, clinicians can now generate instant patient summaries. Over time, this tool has evolved to generate specialty-specific summaries for more than 15 clinical disciplines.

The impact has been tangible – less “pajama time” spent completing documentation, reduced cognitive burden, and more meaningful clinician-patient interactions.

Harnessing Patient Feedback at Scale

AI is also helping HMH analyze patient sentiment at scale. Post-discharge surveys often contain rich insights, but unstructured comments are difficult to process manually. Sameer’s team applied generative AI models to perform sentiment analysis across thousands of survey responses.

This approach revealed trends that might have been overlooked, giving unit-level leaders actionable insights. “We’re not just looking at individual comments but synthesizing them in volume,” Sameer noted. “That allows us to surface patterns and improve care delivery.”

Building Trust and Adoption: Governance and Feedback Loops

Sameer emphasized that technology alone is not enough—adoption requires trust. At HMH, clinicians are closely involved in the development process. “We first understand the problem that needs to be solved, then partner with the clinicians who want to solve it,” he said.

Transparency is key. For example, with clinical summarization, clinicians are reminded that AI is not 100% accurate and should be treated as a decision-support tool, not a replacement. This approach helps maintain trust while reinforcing the principle of keeping a “human in the loop.”

Equally important are continuous feedback loops. From simple thumbs-up/thumbs-down ratings to detailed comments, feedback is built into every deployment. “If we don’t capture feedback, adoption eventually suffers,” Sameer explained.

6 Strategic Focus Areas for AI

On a broader level, HMH has established a governance “pyramid” that ensures AI implementation aligns with organizational priorities. It starts with technical teams evaluating models, includes a cross-departmental governance group with representatives from legal, HR, finance, and clinical domains, and culminates in oversight by the executive leadership team and board. To channel innovation into meaningful outcomes, HMH outlined six focus areas for AI. Every proposed AI use case is evaluated against this framework, with higher priority given to those that align with multiple focus areas and deliver clear ROI.


Disease Detection and Early Intervention

Unlike many health systems that avoid AI-driven disease detection due to regulatory concerns, HMH has embraced it using machine learning models with minimal risk of “hallucinations.” Sameer shared that disease detection emerged as the top priority during a board vote.

Examples include:

  • Mortality Prediction and Palliative Care Nudges: A model predicts a patient’s likelihood of mortality within six months. If triggered, clinicians receive a best practice alert prompting them to consider a palliative care referral. “We’re not making decisions—we’re nudging clinicians at the right time,” Sameer clarified. This approach ensures patients and families receive appropriate support earlier in their care journey.
  • Chronic Kidney Disease (CKD) Detection: Early identification of CKD enables timely interventions that can slow progression and improve outcomes.
  • Chronic Asthma Prediction: Similar predictive models are being developed to flag patients at risk of asthma complications.

These initiatives underscore Sethi’s philosophy: AI should support clinicians in making informed decisions, not replace their judgment.


The Next Frontier: Agentic AI

When asked about future trends, Sameer response was unequivocal: “Agents. Agents. Agents.”

Agentic AI, he explained, represents the next evolution—where different technologies such as large language models, rule engines, and RPA are orchestrated to perform complex workflows end-to-end.

Take denial management as an example. Traditionally, humans analyze insurance denial letters, identify issues, prepare appeals, and resubmit claims—a time-intensive process that affects cash flow. At HMH, an AI agent now handles much of this sequence:

  • Reading and synthesizing denial letters with a language model
  • Applying a rule engine to identify missing information
  • Drafting an appeal letter with generative AI
  • Using RPA to route it to a human for review and submission

By automating most of the process, humans intervene only at the final review stage, dramatically reducing turnaround times and administrative burden.

“This is the evolution of AI,” Sameer said. “Taking insights and moving them into the next step without always relying on a human.”


A Personal Journey into Healthcare

Sameer’s commitment to healthcare is deeply personal. Early in his career, he worked in financial services, while his wife, an occupational therapist, returned home one day and told him, “I made someone walk today. What did you do?” That moment, he recalls, triggered a desire to make a direct impact on people’s lives.

“I realized I could apply my skills in analytics to healthcare and help patients live better—or even die better,” he reflected. Since then, he has remained firmly committed to the field.


Looking Ahead: Data, Capabilities, and Willing Consumers

Sameer is optimistic about the future of AI in healthcare, citing three enablers that did not exist a decade ago:

  1. Data abundance: From EHRs to wearables, data is now ubiquitous.
  2. Advanced capabilities: Off-the-shelf models and cloud platforms accelerate innovation.
  3. Consumer readiness: Patients have become more open to digital care, especially post-COVID.

“Healthcare will always be a people business,” he acknowledged, “but the world—and consumers—are ready for digital means of delivery.”

Sameer’s work at Hackensack Meridian Health highlights a critical shift in healthcare AI: from experimentation to embedded, trusted, and scalable solutions. By focusing on clinician workflows, patient sentiment, governance, and forward-looking technologies like agentic AI, HMH is building a model of AI adoption that balances innovation with responsibility.

As health systems everywhere grapple with clinician burnout, administrative inefficiencies, and rising costs, Hackensack’s approach offers a clear blueprint: start with real problems, keep clinicians engaged, embed AI into workflows, and never lose sight of the human element.

Using AI to Ease Clinician Burden and Deliver Real Value in Healthcare

Season 6: Episode #179

Podcast with Sameer Sethi, SVP, Chief AI & Insights Officer, Hackensack Meridian Health

Using AI to Ease Clinician Burden and Deliver Real Value in Healthcare

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In this episode, Sameer Sethi, SVP and Chief AI & Insights Officer at Hackensack Meridian Health, shares how the health system is embedding AI directly into clinician workflows, moving from theory to real-world transformation.

Sameer outlines practical applications such as specialty-specific clinical note summarization, which reduces “pajama time” for physicians and improves patient interactions, and sentiment analysis of patient survey data, which surfaces actionable insights at scale. He also describes Hackensack’s AI governance framework – a board-approved structure with six strategic focus areas, guided by cross-departmental representation to ensure safe, effective adoption.

Emphasizing that AI solutions serve as decision-support rather than decision-making tools, Sameer highlights the importance of keeping a “human in the loop.” He sees agentic AI as the next frontier – integrating LLMs, RPA, and rule engines to automate complex processes such as prior authorizations and denial management. The result: faster workflows, administrative efficiency, and truly personalized care at scale. Take a listen.

Video Podcast and Extracts

About Our Guest

Sameer Sethi, is the SVP, Chief AI & Insights Officer at Hackensack Meridian Health Mr. Sethi is a seasoned leader and expert in healthcare data and analytics with a proven track record of enabling use of data and analytical techniques to drive distinctiveness and deliver transformative impact. He has focused his career on data, technology, and innovation for healthcare providers. Starting his healthcare career in EMR implementations motivated Mr. Sethi to find ways to use digitized medical data to improve patient care, influence clinical workflow and provider network operations. He has since operated at the cross-section of healthcare and technology to improve quality, access and cost-of-care delivery.

Mr. Sethi previously worked at Mount Sinai Health System, McKinsey, Bon Secours Mercy Health and now serves as Chief AI & Insights Officer at Hackensack Meridian Health. His experiences in data and analytics roles across consulting and health systems gives him diverse perspectives on the challenges facing providers in data and insights enablement and technology adoption. Mr. Sethi and his team are currently focused on accelerating the use of Artificial Intelligence (AI) and Machine Learning (ML) to deliver high quality, affordable, more accessible, and more efficient healthcare. Recently, Mr. Sethi was named by Becker’s Hospital Review among leading hospital and health system chief data and analytics officers making an impact.


Ritu: Hi Sameer. Welcome to our podcast, The Big Unlock, season six. My name is Tum Roy, and I’m the Managing Partner at Damo and BigRio, based out of Gurugram, India. Always a pleasure to chat with CMIOs, CIOs, CDOs, and Chief Information and AI Officers about all the latest developments in healthcare systems. I hope this will be a really exciting and engaging conversation. Welcome to the podcast once again.

Rohit: Thank you, Sameer. Welcome to the podcast. I’m Rohit Mahajan, Managing Partner and CEO at BigRio. Over to you.

Sameer: Thanks for having me, folks. Excited about this conversation.

I’m Sameer Sethi. I function as the AI and Insights Officer for Hackensack Meridian Health. We are a health system based out of New Jersey, a combination of 18 hospitals and close to 500 care sites. We do this with the help of around 40,000 team members, both clinicians and non-clinicians. Our care is mostly across New Jersey, and we also have a very big digital presence.

My focus within the organization is primarily on four areas. One is data and analytics. This is where we produce and ingest data from various source systems, with our electronic medical record being the biggest one. My team helps normalize that data and make it available not just as raw data, but also as insights.

The second is AI. This involves moving beyond explaining what has happened to understanding why it happened and predicting what may happen next. Those capabilities are now more easily available to us through third-party models. Building capabilities that leverage large language models and generative AI is a big piece of our portfolio as well.

The third is robotic process automation. This is where we write code to emulate human functions where appropriate. We have a large program that focuses on automating mundane tasks or tasks that require accuracy that machines can deliver better, or speed that humans cannot match. We now have over 200 automations in production today—a really large portfolio we’ve been building for quite some time.

And the fourth is software development. At times, when purchasing software or capabilities is not viable for Hackensack—either because it’s not what we need, it’s too expensive, or it’s not available—we will write software and deliver it to our clinicians and operators.

So that’s what I do for Hackensack. I’ve been here for three and a half years, and it’s been a really rewarding experience.

Ritu: Thank you for that introduction, Sameer. Lots to talk about. We were very interested to hear how you think AI is not just for the sake of AI, but about putting it to the right use. We would love to hear about some applications at Hackensack that you’ve built where you really feel AI has demonstrated transformational change and made the patient experience better.

Sameer: Absolutely. We’ve been excited about this. We’ve been at it for almost three years now, with a very heavy focus on AI in the last two years. Three years ago, the conversation on AI was more about machine learning. Now it’s more about generative AI, and the talk track behind why this is so important has changed as well.

At Hackensack, because we are so serious about this, we’ve really thought about how to put AI to use. This goes beyond just talking about how AI is good and the governance around it. While we do that, we are also focused on building the right solutions. There’s one thing to look at tools like ChatGPT and say you can ask a question and get an answer back. But the real value is in embedding these technologies into workflows. That’s what we are most focused on.

Giving someone access to a conversational AI—whether by voice or typing—gets you to a certain point. But the real impact is in customizing it for a clinician at the time of care. That’s where Hackensack has put its efforts.

A good example: as a hospital system, our clinicians see patients, and when they do, they face a sea of valuable data. Reviewing that data takes time—time they often don’t have, or time taken away from the patient. One of our first use cases when large language models became available was to use generative AI to summarize that data. We essentially wanted to improve the experience.

We’re all consumers of healthcare. I’m sure you’ve been in situations where you go to a doctor’s office and the doctor is staring at the screen while trying to listen to you. What that clinician is doing is trying to understand your clinical record, which takes time. We made that easier. We provided a button for clinicians to summarize a patient’s information instantly—in seconds.

That use case has evolved. Initially, the summaries were general. But through feedback we realized summaries had to be by specialty. An oncologist, for example, needs different details compared to a primary care physician. So, we started with eight specialties and today it’s almost 15, giving physicians the option to summarize by specialty. That has been very valuable.

That’s one way we’ve used generative AI technology and put it to good use. This continues to grow. For example, we’ve also applied it to patient survey data. We collect survey information from patients and families post-discharge. The structured data was already in dashboards, but we realized patients were typing a lot of comments.

So, we created sentiment analysis on top of that unstructured data and gave it back to the business at a unit level. This wasn’t happening before. Operators can only read so many comments. By synthesizing comments in volume, we can surface trends across unstructured data. Again, we used large language models to deliver those insights back to the business.

This is an important part of the conversation. When we talk about AI and how to put it to use, there’s the aspect of finding the right use cases, but there’s also a technical side. There’s a lot of discussion around tools like ChatGPT not giving the right answers. At Hackensack, we put together a center of excellence that focuses on indexing. Why? Because indexing makes the answers better.

So, at Hackensack we’ve not only been exercising the muscle of finding the right use cases and delivering them, but also learning how to harness the technology and use it better. This technology is here to stay. It’s really good—you just have to know how to put it to the right use.

Ritu: Thank you, Sameer, for sharing those use cases. It’s really incredible that you were able to do clinical note summarization, especially across so many specialties, and provide customized information to physicians. Did you feel there was any pushback? How did you handle the literacy or acceptance part of it? Because some people we talk to feel innovation is difficult for healthcare professionals to accept, and it takes much longer. I’m sure they saw the benefits, but it might have been a steep curve. What was your experience?

Sameer: At Hackensack, this has been a bit of us learning from our mistakes over time. How you build these things is really important. And when I say “how,” I mean the non-technical side.

What we did well was first understanding the problem that needed to be solved, and then partnering with the clinicians who wanted to solve it. When there’s mutual participation, there’s better acceptance. We also set clear expectations from the start—what this technology is, what it isn’t, how accurate it is, and how accurate it isn’t.

For example, with clinical note summarization, our intent was never to replace anyone’s work. Our intent is to help people work at the top of their license. So, we tell clinicians: this isn’t 100% accurate. You still have the whole patient record if you want to review it. If something in the summary doesn’t look right, it’s your obligation to check the full record. But what we’ve given you is a strong head start. That’s what reduces pajama time. That level of transparency has helped us get much better acceptance.

And by the way, my team and I welcome pushback. It teaches us a lot. As technologists, we’re keen to build solutions, but they have to be used by clinicians. When we get pushback, we consider it feedback. Maybe we’re not explaining the solution well, maybe we haven’t designed the right user interface, or maybe we haven’t embedded the capability properly into the workflow. We look at the positives in pushback, and it has worked to our benefit.

Ritu: That reminds me—many years ago I attended a lecture by Marshall Goldsmith where he said, “I don’t know why people call it feedback. It should be called feed-forward.” Because anytime you get feedback, it’s actually helping you move forward. I really love that line and share it with so many people.

Sameer: We actually make a very strong attempt to build feedback—or feed-forward—mechanisms into almost everything we deliver. Not capturing that feedback over time results in lack of adoption.

Ritu: Yeah, because you start drifting away from what people actually need.

Sameer: Exactly. Even a basic thumbs up or thumbs down is valuable. A thumbs down signals us to go back to the user and ask, “What happened here?” We try not to complicate feedback collection, but we always make sure to build feedback loops into our solutions.

Ritu: So, you’re saying one of the keystones of AI adoption at Hackensack is bringing everybody along for the ride and ensuring buy-in from all stakeholders.

Sameer: You know, I also want to add something valuable to this conversation—we’ve thought a lot about governance. I think all of us have, but it’s still such a word out there and people don’t always know what it really means. So I’ll tell you our journey.

We call it our governance pyramid. At the bottom is the technical tier, which is our team evaluating and building AI. On top of that, and more important in this context, is what we call our AI and Automation Governance Group. This is made up of 13 domains across the health system coming together. When we built our governance process, we invited representation from every domain—legal, HR, clinical documentation, finance, and others—so that every voice had a seat at the table. That inclusion really helped us.

Then we have the next level up, which is our governance committee, primarily the executive leadership team. These are the folks that help us prioritize, because everything can look good, but we can’t do everything. So the committee decides which problems to solve first and which areas deserve focus. That model has been very helpful in keeping us on track.

Our board has also played a very large role, and sitting on top of all this we had our annual summit last year. As you can imagine, when we started doing AI—and especially when generative AI came in—there was a rush of demands from the business. Everyone was saying, “I hear this is available, do this,” or “This looks really cool, let’s try it.” At a certain point, I honestly didn’t know what direction to look in.

So we went to the board and established six areas of focus for Hackensack. The reason we did this was because we knew if we didn’t, we’d end up chasing shiny objects. With the help of the board and our executive leadership team, we identified six strategic areas, and the principle was simple: if a use case didn’t fall into these areas, we wouldn’t do it.

The six areas are creating personalized and equitable patient experiences, streamlining administrative and clinical efficiencies, capacity management and reducing burnout, disease detection, precision treatment by customizing therapies for patients, and research and innovation. These are broad enough that most initiatives can align, but focused enough to give us discipline.

Every use case that comes to the governance committee now goes through a scoring process, which looks at ROI and how many of these buckets it fits into. The more it aligns with our focus areas, the higher its score, and that’s what determines where we put our efforts. That process has been very valuable for us and has helped us stay focused on the right problems.

Ritu: So, most of the CIOs we talk to say that they’re concentrating more on the digital front door and the patient experience. They want to stay away from disease detection and anything that requires like FDA approval. I’m curious, when you talk about disease detection, what are some of the use cases there and how do you get around that?

Because. Exactly the problems that you mentioned earlier with LLMs still having hallucinations and other things, and a human in the loop having to review all the results. So, for disease detection, how do solve that.

Sameer: That’s a great question, and I think you’re asking it with generative AI in mind, which makes sense because that’s where most of the buzz is right now. But the reality is that disease detection is much more a machine learning use case than a GenAI one. With machine learning, you don’t really have hallucinations, or they’re almost nonexistent. And that’s an important distinction. Too often people hear “AI” today and immediately think only of GenAI, when in fact, there’s so much more to it.

What’s interesting is that when we had our last board summit, we actually ran a voting exercise across the six areas of focus we had defined. And surprisingly, disease detection came out on top. Right after that was streamlining administrative efficiencies and addressing burnout—clinicians, as you can imagine, pushed for burnout relief, and operators pushed for efficiency. But overall, the board said disease detection should be front and center.

And honestly, it makes sense. We’re a hospital system. If we can detect disease earlier, we can keep patients healthier. That’s the whole point of what we do.

Let me share a couple of examples. The first is mortality detection. This one is personal for me. A few years ago, I lost my mother-in-law, and I’ll never forget the palliative care team telling us, “We should have been here six months ago.” I remember sitting with the physician and asking, “What happened? Why didn’t anyone flag this earlier?” And the honest answer was, they’re not wired that way. Physicians and nurses are trained to keep fighting, to keep trying to fix the patient. Letting go and saying, “It may be time for palliative care,” doesn’t come naturally.

So what we did was build a model that produces a mortality score. And then we embedded it directly into the clinical workflow. Here’s how it works: a clinician might go into the patient record to prescribe something simple, like Tylenol. At that moment, a best practice alert pops up and says, “The model predicts a high likelihood of mortality within six months. Consider palliative care.” The clinician can review the labs, the patient history, and if they agree, they click “yes.” That automatically creates an order for the palliative care team to engage. If they don’t agree, they hit “no” and provide feedback, which we use to improve the model.

So what we’ve created is a chain: a mortality score that becomes a nudge, that then becomes an order—all with the clinician still in the driver’s seat. And the result is that patients are now being referred to palliative care much sooner. They likely would have ended up there eventually, but now families are getting the support earlier, which makes a huge difference.

Another example is chronic kidney disease. We’ve built capabilities that allow us to detect CKD much earlier in the progression of the disease, and that early identification can dramatically improve patient outcomes. And right now, we’re also working on chronic asthma detection.

So those are just a few of the use cases, but the bigger point is this: disease detection is core to us as a health system. It’s not about replacing clinical judgment. It’s about surfacing signals—signals that help our clinicians make the right calls, earlier, and give patients better care.

Ritu: That’s really interesting because we haven’t heard that from other hospitals, so, that’s really incredible to hear.

Sameer: You know, one thing I always want to emphasize is that what we’re building are not decision tools—they’re decision support tools. There’s a big difference. The final call always rests with the clinician. Take the mortality model I mentioned earlier: yes, it provides a nudge, but alongside the “yes” button, there’s always a “no” button.

Ritu: You’re alerting them, but the decision is still theirs.

Sameer: Exactly. And when they press “no,” they’re asked to provide a reason. That feedback is incredibly valuable to us. It helps us refine the model, learn where it might not align with clinical judgment, and continue improving it. But at the end of the day, the conversation with the patient, the clinical decisions—that all stays firmly in the hands of the physician. What we’re doing is simply surfacing insights at the right moment, in a way that makes patient care better.

Ritu: I think this has been a really insightful part of the conversation.

Thank you, Sameer, for sharing those use cases for disease detection. Looking forward, you know, if you looked at the next six months or a year or maybe two years, what do you think the top three trends in AI would be? You know, I know we talked a little bit about agents in our prep call yesterday, and uh, you had like a very good story about agents as well, where you said that agents are, you know, more, mostly an orchestration platform.

So, if you would like to talk a little bit about that, share what you think the next three big trends are going to be. Or not trends, but like things which are going to, you know, come to the front line and be a focus area of focus for Hackensack.

Sameer: I’ll tell you my top three are going to be agents, agents, and agents. Agents. This is an opportunity for us to use technology that is here now to orchestrate. For me, when I think about agents, it’s a concept. The concept is: how do you orchestrate different technologies to work together and provide an output that a human can interact with better? That’s an agent.

In the past, folks like me have tried to build these ourselves, similar to how we built machine learning models. Today, those models are available—now they are machine learning models versus large language models, but just using that as a concept. What I’m trying to portray is that we’ve been trying to build these agents for a long while, but the tech had to be developed from scratch. Orchestrating RPA software and a database to all work together in a certain sequence wasn’t easy to do. We did it, and today, technology companies like UiPath, Google, and others have built platforms to orchestrate that.

Now the orchestration has become a lot easier. Why is orchestration important, especially in healthcare? Because we are now not just relying on humans to do certain things. In the past, we built AI and gave it to a human. Rightfully so, in some situations, a human has to interact with it, like the mortality example. But there are instances where we’re building AI signals that do not require a human. The next step can still be taken by a machine.

In the past, when building these signals, we would rely on a human to interact with it and do something, even when the human wasn’t needed.

That doesn’t hold true for all use cases and applications. In certain places you still need humans, but that’s what I’m most excited about. In places where I don’t need a human, how do I build and take it to the next step? Because then those insights will be used, rather than relying on a human who may not have time, or the program lacks buy-in. What I’m most excited about is how do I take those instances and use all these insights more effectively. Now you can move to the next step without relying on a human. I think that is the evolution of AI, and that’s why I choose this as my top three focus areas.

Now look at the portfolio I’m privileged to own: RPA and AI and software. Now the world has given me a platform where I can plug all this together. I’ll use an example: as a health system, we receive a lot of denials from insurance companies.

Rohit: Mm-hmm.

Sameer: We rely on humans to take that denial, synthesize it, get information, then generate a new appeals letter and send it. That’s a process—requires expertise, humans, and time. The impact is that getting this together delays the cash flow until the insurance pays. What we’re building is an agent that will do most of that work: receiving a denial letter, extracting information about the denial (maybe a missing modifier or pre-authorization), then using a large language model to synthesize that information.

Then it taps into a rule-based engine we built: if the denial reason and modifier meet a certain rule, do this. I’m oversimplifying, but it relies on the rule-based engine to identify the opportunity and the deficiency in the previous claim or submission. Then it creates a new claim or appeal, using generative AI. RPA pushes it to a human who reviews, approves, and then it’s processed again with the insurance company. This was all done by humans previously. Now, orchestration platforms can switch between a large language model, a rule-based engine, generative AI, and RPA—moving all these pieces together. That saves time and a lot of money. Humans are still involved toward the end, reviewing, but the things we didn’t need humans for are now done by machines.

Ritu: Amazing. Great to hear that, Sameer. Rohit, do you have any last questions for Sameer?

Rohit: Y Sameer has given a lot of food for thought. I’ll be taking exhaustive notes. I have enough questions for another complete podcast, but what I’d like to ask you—and I’m very interested in the center of excellence on the data indexing part, so I’ll come back to you on that as well—but could you share with listeners what motivated you to get into healthcare, how you started, and your story? That would be great to end the podcast with.

Sameer: That’s a very good question. I love sharing this story. This goes back almost 15, 16 years. I worked in financial services. I married Simon, she’s an occupational therapist. She works as hard as I do, if not more. I still remember her coming home after we got married in 2006. I was at Deloitte, not in healthcare then, and she said, “I see you on the computer all day. You do great work and provide for the family, but I want to share some feedback: I made someone walk today. What did you do?” That triggered something in me. I wasn’t much of a charitable person, but I thought—maybe I can do something that saves a life or saves money and care. I looked into different things and eventually, I landed in analytics.

That’s what motivated me—I wanted a job and career where I could make an impact without going back to school to become a doctor or clinician. This is my calling, where my team’s hard work hopefully helps someone live better, or maybe, as in the example, die better. For me, it’s a very passionate thing. I tell people I came into healthcare and am never leaving, just for those reasons. Whenever I think about an opportunity beyond healthcare, I hear my wife saying, “I made someone walk—what did you do?”

Rohit: That’s an amazing story, Sameer. There is a saying at Harvard Business School about the benefit of a physical footprint, but what about an intellectual footprint that can span the world? You have so many great ideas that can be propagated. I’ll definitely be back in touch with you on that. Thank you so much.

Sameer: What’s most exciting for folks like me is that, first of all, the data is there. There’s so much data being generated now—from our watches, phones, doctors—it’s all available. Second, we’re not alone anymore. I remember the days when the only model you had was one you built yourself. Now, Google and OpenAI—everyone has a model. There’s so much opportunity between available data and capabilities. The third thing is willingness—consumer willingness. I have a relative I help with doctor visits. Pre-COVID, she always wanted to visit her doctor in person. Post-COVID, she asks, “Can I take a telemedicine appointment?” It’s a big change.

Consumers are open to digital means of delivery now. Technology will do well, though healthcare will always be a very people-centric business. But I’m excited—the data is there, capabilities are there, and consumers are ready.

————

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Driving Digital Transformation in Healthcare: Insights from Inderpal Kohli

Driving Digital Transformation in Healthcare: Insights from Inderpal Kohli

Driving Digital Transformation in Healthcare Insights from Inderpal Kohli

Healthcare is undergoing a profound shift, with technology playing an increasingly central role in improving patient outcomes, clinician efficiency, and organizational sustainability. Few leaders have been as deeply immersed in this transformation as Inderpal Kohli, a veteran healthcare executive technology leader with over two decades of experience across institutions such as Columbia University Medical Center, Hospital for Special Surgery (HSS), and Englewood Health.

In a recent episode of The Big Unlock podcast, Inderpal shared his journey, lessons learned, and his perspectives on the future of healthcare digital transformation. His experiences shed light on how health systems can approach innovation thoughtfully, balance risks with rewards, and deliver tangible results for both patients and clinicians.

A Career that Blends Technology with Care

Like many technologists who entered healthcare by chance, Inderpal’s career began in software development for the banking and financial industry. A project assignment at Columbia University Medical Center introduced him to biomedical informatics and clinical research systems—a turning point that solidified his decision to stay in healthcare.

At Columbia, he witnessed firsthand how research innovations could translate from “bench to bedside.” That early experience taught him the importance of building digital solutions that directly impact patient care. His subsequent roles at HSS and Englewood Health gave him opportunities to work on digital transformation initiatives at scale—from EHR implementation and clinical system integration to enterprise-wide modernization in cybersecurity, networking, and data centers.

This journey highlights a central theme in healthcare IT leadership: success comes not just from technical expertise, but from understanding the continuum of patient care and clinician needs.

Digital Pathology: A Breakthrough in Diagnostics

One of the projects Inderpal is most proud of is the digital pathology transformation at HSS. While radiology has long been digitized, pathology remained tied to glass slides and microscopes. Recognizing the inefficiencies of this approach, he championed a program to digitize pathology workflows, working with Epic, PACS vendors, and scanner providers.

The timing coincided with the COVID-19 pandemic, which accelerated adoption. Within a year, 70% of pathology cases were being diagnosed digitally—a remarkable achievement for a specialty deeply rooted in traditional methods.

The benefits went beyond efficiency. Digital pathology allowed pathologists, surgeons, radiologists, and infectious disease specialists to correlate images seamlessly, improving collaboration and patient care. It also opened the door to AI-powered tools for cell counting, pattern recognition, and diagnostic quality improvement.

As Inderpal noted, digital pathology was “a first in the country” at that time and set the stage for broader adoption of AI in diagnostics.

 

Patient Engagement and Remote Care Yield Measurable Outcomes

At Englewood Health, Inderpal spearheaded a three-pronged digital physician strategy:

  • Patient engagement and self-service: By expanding digital front doors and enabling online scheduling, Englewood achieved an 18–20% increase in digital appointments, despite the cultural challenge of convincing physicians to open their schedules.
  • Proactive outreach through digital campaigns: Using Epic’s CRM platform, Englewood launched automated campaigns for preventive care screenings like mammograms and colonoscopies. The results were significant—21% success in first-time mammogram screenings and 6% success in new preventive screenings, far outperforming traditional paper-based outreach.
  • Remote patient monitoring (RPM): Starting with blood pressure monitoring, the program showed early success, with 84% of participating patients demonstrating improved outcomes within six months.

These initiatives reinforced a powerful lesson: when thoughtfully integrated with core systems like Epic, digital engagement strategies not only enhance convenience but also deliver measurable improvements in population health.

 

Supporting Clinicians Through Ambient Technology and AI

A recurring theme in Inderpal’s work is reducing the burden on clinicians. At Englewood, he introduced ambient documentation technology to relieve physicians of the after-hours “pajama time” spent completing charts.

The impact was significant:

  • 40% reduction in after-hours documentation among physicians using ambient solutions.
  • Improved patient satisfaction, as doctors could focus more on conversations rather than typing notes.
  • Potential financial benefits from more accurate coding, with some organizations reporting savings of up to $13,000 per physician per year through improved HCC and E&M coding.

In addition, AI-driven tools are now assisting with MyChart message responses, chart summarization, and prior authorization workflows. By embedding these technologies within the EHR, organizations can scale efficiencies while maintaining clinician trust.

 

Overcoming the Challenges of Digital Transformation

Despite the successes, Inderpal is candid about the challenges. He categorizes them into technology, process, and resource barriers:

  • Technology: Beyond obsolete systems, technical debt often shows up in how solutions were originally designed without a digital-first mindset. Fixing foundational data definitions and architectures is critical for making data-driven decisions.
  • Process: Healthcare organizations must embrace agile experimentation rather than expecting every project to succeed. Piloting solutions for 90 days, measuring KPIs, and being willing to walk away is essential—yet culturally difficult for organizations used to long project cycles.
  • Resources: IT teams trained in controlled clinical environments must adapt to the unpredictable world of patient-facing solutions, where user experience (UX) plays a critical role. Many organizations are now building dedicated digital teams with consumer-oriented skills to bridge this gap.

These insights emphasize that digital transformation is as much about mindset change as it is about technology adoption.

 

The Future: AI, Agentic Workflows, and Personalized Medicine

Looking ahead, Inderpal sees AI and agent-based automation as central to the next phase of transformation. While today’s deployments focus on low-risk, non-clinical areas such as scheduling and payments, he predicts rapid expansion into clinical workflows.

  • Ambient AI will become pervasive across inpatient and outpatient care, evolving beyond physician documentation to nursing and other clinical roles.
  • Agent AI will transform back-office functions like prior authorization, denials management, and patient communication, streamlining administrative burdens.
  • Digital twins—though currently cost-prohibitive—hold promise as a game-changer, enabling organizations to simulate and test changes before real-world rollout.
  • Ultimately, the pinnacle of AI in healthcare will be personalized medicine, where treatments and dosages are tailored to individual patients rather than populations.

Inderpal captures the spirit of this transformation with a memorable quote:

“AI won’t replace clinicians, but clinicians who use AI will outperform those who don’t.”

The message is clear: healthcare’s future will be shaped not just by tools, but by how leaders and clinicians reimagine workflows, patient interactions, and care delivery through these tools.

Price Transparency, Data, and AI for a Better Healthcare Experience

Season 6: Episode #178

Podcast with Ramesh Kumar, CEO and Co-Founder, zakipoint Health

Price Transparency, Data, and AI for a Better Healthcare Experience

To receive regular updates 

In this episode, Ramesh Kumar, CEO and Co-founder of Zakipoint Health, shares his perspective on addressing healthcare’s persistent challenges—high costs, lack of price transparency, and fragmented care. He emphasizes that patients, or ‘members,’ often struggle to understand the true value of care, even as regulatory pushes for transparency continue.

Ramesh highlights how greater data visibility and patient empowerment can shift the system toward value-based outcomes. He emphasizes that true digital transformation goes beyond compliance and organizations must leverage transparency in data to create actionable insights for patients, employers, and providers alike. He also discusses the role of AI and agentic AI in simplifying complexity, reducing administrative burden, and enabling more personalized, efficient care delivery.

Ramesh underscores the need for co-creation between payers, providers, and technology innovators to build sustainable solutions. For him, the convergence of transparency, digital innovation, and AI marks a pivotal moment to reimagine healthcare’s future. Take a listen.

Video Podcast and Extracts

About Our Guest

Ramesh Kumar is the CEO and Co-Founder at zakipoint Health. He helps Healthcare Benefit Administrators deliver value to their self-funded employers through data driven cost containment and high impact member experience that steers the population.

With over two decades of experience in healthcare analytics, Ramesh helps self-funded employers optimize healthcare programs, reduce costs, and enhance care quality. His focus on personalization, patient engagement, and benchmarking provides insights that improve transparency and allow employees to better manage their healthcare expenses. Throughout his career, he has led business development, marketing, and product innovation to simplify healthcare, delivering tools that lead to lower costs and better outcomes.


Q: Hi Regina. Welcome to The Big Unlock Podcast. I am Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting. It’s so nice to have you on the podcast, especially since you are a practicing physician. Would you like to introduce yourself to the audience? 

Regina: Well, Rohit, thank you so much for having me, especially since I am a practicing physician. I’m not a technical founder or someone in the data world full-time.

For you listeners, I am Dr. Regina Druz. I’m a board-certified cardiologist since 2001. I’ve gone through all the traditional cardiology training and worked in hospital settings, academic settings, and private practice. Along the way, I went down the entrepreneurial route, which led me to personalized precision medicine, longevity medicine, and rethinking what cardiology should be. One of my colleagues calls it “comprehensive cardiology.” It’s about redefining what I can bring to patients and how they can benefit beyond traditional, expected care.

Q: That’s very cool, Regina, to know that you are now on the path of your entrepreneurial journey as well. So tell us, what attracted you to healthcare in the first place? How did it all start?

Regina: Good question. My parents are not physicians, but I grew up with amazing role models. My aunt and her daughter, my cousin, were the original power women, though the term didn’t exist then. Both were physicians—obstetrician-gynecologists—and were excellent at what they did. My aunt, after her education, was asked to go to an underdeveloped country to help build healthcare and improve maternal mortality. Many women at that time were dying in childbirth, and she brought in new practices that made a huge impact.

They were inspiring role models. Since I was young, I said, “I’m going to be like them. I’ll be a doctor, I’ll be strong, I’ll cure the world.” My father, an electronics engineer, pushed me toward technical fields, and I enjoyed science. But biology really grabbed my attention. The rest was conventional: medical school, residency, fellowship.

I didn’t end up a gynecologist, which disappointed my family a bit. They said, “Oh my goodness, you’re choosing to be a cardiologist?” But I said, “Women can do cardiology too.” Luckily, more women have entered cardiology over the past 20–30 years, and specialties once dominated by men are now more welcoming. Women are making their mark. That’s me in a nutshell.

Q: That’s a very cool journey, Regina. So you talked about something in your introduction which caught my attention around personalized medicine and longevity. So please tell us like what does it all mean and how’s it coming together?

Regina: That’s a great question, Rohit. Maybe I’ll take you back to some of my more traditional cardiology days. When I was working in a hospital setting, I was responsible for an area involved with cardiac imaging. We have various procedures to image the heart, understand how it functions, if the blood vessels are open, if the valves are doing okay, and if we can foresee the future and understand what’s going on. My particular area was nuclear stress tests. Patients typically had to exercise on a treadmill as part of a stress test. For those who couldn’t exercise, we used a chemical stress test, but the majority exercised on a treadmill. We would inject a little bit of radioactive material to see how blood flows into their heart and determine if their heart is healthy.

What came out of it is that as doctors, we were a bit biased. We would expect younger people to do better, and that older people would not do as well. But 20–30% of the time, we would get the opposite—an older person who did much better than expected, and a younger person who did very poorly. This started my journey into personalized medicine. I started to ask if there was a pattern—what are the older people doing to preserve this ability into older age, and what are the younger people doing, or not doing, that actually takes away from what we think they should be able to do, cardiac-wise and physically?

I started asking patients questions that weren’t part of our standard intake. Do you exercise at home? Do you garden? Do you travel? What do you like to do? What gives you purpose? I looked at other physicians who introduced this idea of “n of one,” of personalized medicine. There are reasons, systems biology, root causes driving health and longevity, and also driving disease. It’s not standardized; it’s not a population-based metric. It’s literally the N of one.

That piqued my curiosity, so I decided that the best way to address it was to take what I know in cardiology and bring it into a personalized medicine approach. The best fit for it was integrative and functional medicine, where we could expand our lens and look beyond just hard numbers—like cholesterol, blood pressure, and medications—and ask why levels are elevated, and what we can do lifestyle-wise to optimize health. Optimized health is a major contributor to longevity. Physical health, cardiovascular health, brain health, and systemic health are really the foundation of any longevity equation. You can’t talk about longevity if health isn’t optimal.

That was the beginning of going off the beaten path. My colleagues thought I was crazy because they could not understand it. They said, you have great credentials and roles. At that time, about ten years ago, there was no room in the institutional setting for this. There could have been some departments inclined toward integrative or complementary medicine, but nothing institutional. That meant going on my own, right as medicine was beginning to consolidate. People said I was insane and would do very poorly. I opened my first tiny practice with about three patients in an area saturated with cardiologists. Even back then. Today, it’s exponentially so. I’m here to tell you this works, and this was not only a huge benefit to my patients, but it was a benefit to me.

Q: That’s awesome, Regina. And I know you are very interested in all the new technologies coming our way. In any podcast these days, we have to touch upon AI. How do you look at AI and digital health from the lens of cardiology? What does it mean to you, and how do you see some use cases from a physician, patient, and caregiver perspective? How does it all play out in your world?

Regina: It’s a great question, Rohit. I was an early adopter, so back then there weren’t as many things available to us. Right now we have so much more. In any digital health domains, in cardiology or any specialty, you have to ask how they benefit a patient, and how they help doctors, patients, and nurses to do the right thing without burning out, saving on cost, and staying compliant with regulations.

I started with telemedicine. I was an early adopter, and since my practice was personalized, telemedicine is a great tool. It gives patients a lot of access, but it has a major deficiency: you’re not getting a physical exam. You can’t listen to a patient or do those things. I needed their blood pressure, electrocardiogram, and a couple of other measures to assess if they are okay. This led me to explore digital tools available—there are quite a few. For example, a company called AliveCor created a device you could clip onto an iPhone, and by putting two fingers on metallic plates, it would record a single-lead electrocardiogram. It wasn’t a full EKG, but it was the beginning.

Other companies like Omron and Withings came out with Bluetooth-enabled blood pressure cuffs, letting patients check their blood pressure and transmit the information to me. For the first time, with telemedicine adoption, I wasn’t blind anymore. When COVID came and in-person visits were canceled, I wasn’t stuck. I already had the telemedicine platform and some of these tools.

Now it’s even more diverse. I routinely use the tools from these companies. Now we can do a Bluetooth-enabled 12-lead electrocardiogram with AliveCor—no traditional machine needed, just a small remote controller with a button. Cardiac and vascular ultrasounds now have devices like Butterfly IQ, which has ultrasound on a chip that connects to a phone or iPad, providing diagnostic images affordably.

Digital devices first went to practitioners and are now available to patients. Patients use Apple Watch, Withings, Fitbits, and other trackers. Suddenly we have overwhelming streams of data. Now, AI has come into the picture. Patients are becoming “citizen patients”—they investigate themselves, upload their data into large language models, and get outputs. They have agency to do this, even if they can’t always tell whether the output is correct.

These data streams are becoming routine in medical practice. Places like Mayo Clinic use large data repositories and AI tools to analyze electrocardiograms and predict heart failure years before symptoms appear. This is a huge opportunity. We could work with high-risk individuals preventatively, sparing them clinical heart failure. Once someone has their first heart failure episode, five-year mortality is 50%. Imagine if we could be ahead of this curve.

We are evolving from curiosity to clinical implementation and, hopefully, to clinical competency—making this standard care, not just a nice-to-have. Regulatory bodies recognize the value of these devices. Medicare, for example, pays for remote care monitoring (RCM), usually reserved for higher-risk patients and accomplished through digital devices and AI interfaces. They allow us to identify what’s happening—a sort of third eye.

Q: That’s pretty deep usage of AI and digital devices in different ways, Regina. One other thing—I know you mentioned large language models. Another thing that’s become very popular is AI coding tools. We were just chatting before the podcast, and I have several physician friends experimenting with such tools. So tell us your experience. You mentioned an article too; tell us more about what you’re seeing in this space. 

Regina: This is very interesting because when ChatGPT became a household name, I said, okay, let me give it a try. At the time, I was studying for my boards. Cardiology boards have different ways to maintain certification. One newer way is that every year you do a small cardiology knowledge exam. It was time for my exam, and I was studying using traditional stuff from the American College of Cardiology, but some explanations to questions left me wanting more. So I started putting those questions into ChatGPT, and it gave me deep, nice, long explanations that covered some of my blind spots. That was interesting. I think large language models, when they don’t hallucinate, are great educational tools. You can constrict them to look at specific journals or guidelines.

But the real breakthrough for me as a practicing clinician came from ambient AI scribes. They became indispensable in my practice. There are several companies; I personally use one called Heidi Health, a startup from Australia. Most people think ambient AI scribes just catch conversations and save time on notes, which is true, but there was something else—a positive externality. The structure of the AI scribe allowed me to generate versions of notes, including one I could send as a message to patients via patient portals. This summarized next steps clearly—what they need to do and how. Instead of reinventing this, after some tinkering, I generated a template I liked. This enhanced my patient care meaningfully by adding another touchpoint, another opportunity for engagement. It also helped me not have to remember everything but to clearly outline the next step.

In personalized medicine and longevity health optimization, this requires a lot of participation. It’s very different from traditional medicine where doctors just tell patients what to do and wait for them to come back. Here, it’s the opposite; you need to reach out regularly. The AI scribes gave me that ability to be efficient and effective and to “excite and delight” patients with better communication.

As a clinician entrepreneur, I am also experimenting with Agentic AI. Some experiences are helpful; some are questionable. One unsettling issue, raised by AI experts like the CEO of Tropic, is that AI is a black box. We lack full visibility into how it generates answers, especially with agent AI. I asked it for a simulation on a complex patient with cardiac and immune issues, including all parameters we know. The AI produced a great output with references and did not hallucinate. My initial hunch was correct, but I wanted to know how it built the case. In medicine, we use frameworks for diagnosis, workup, and prognosis—check and balances learned from real outcomes. That’s where AI’s black box presents challenges.

Whether it’s LLMs or chatbots or more complex agent functions, we are in uncharted waters. We will use them going forward, but we need more visibility into their processes for trust and safety.

Q: Of course. Regina, I think we hit on something during our pre-podcast discussion about the digital divide. You said people with high agency will propel ahead using such tools. Could you explain your thought process behind that? 

Regina: Great question, Rahi. The digital divide often comes up with digital tools like wearables or telemedicine platforms. We have to ask whether certain patient groups will face barriers. Older patients may not be technologically savvy enough to navigate telemedicine or connect Bluetooth-enabled devices like blood pressure cuffs. They might struggle with mobile apps or synchronizing devices. Plus, healthcare privacy is heavily regulated.

Traditionally, the digital divide affects older patients, those with cognitive issues, non-English speakers, and those who can’t afford or access these tools. But I believe another digital divide is forming. Recently, I read a Wall Street Journal piece about AI tools that almost anyone can access at a free level. To truly benefit, users must be “high-agency” individuals—able to instruct the tool, understand its limitations, refine outputs, and keep moving forward.

I see this with my patients. Those with high agency get more information, more touchpoints, and a very different experience managing their health compared to those less inclined to use these tools. Physicians sometimes reinforce this divide. One colleague, Dr. Kim Williams, former ACC president and lifestyle medicine champion, uses ChatGPT as part of his team. He inputs patient scenarios—not for medical advice but for cultural context—to help patients transition to healthier diets without overwhelming them.

Q: That’s awesome. As we close, Regina, looking into your crystal ball over the next 3–5 years, what exciting things do you see coming our way? 

Regina: It’s an interesting one because I ask it to myself very often. In the physician community, there are a lot of voices who say AI is going to replace doctors. And then, from the tech world, there are predictions like no more radiologists.

Of course, there are other voices that are more introspective and say no, AI is not going to replace doctors. To me, it’s very clear that we are going to see in the next five years a rapid emergence of agentic AI in all verticals of healthcare. It’s going to take care of mundane tasks like pre-authorizations, appointment scheduling, and supply chain management.

Then it’s going to really make its mark in staffing decision making, especially when calibration is needed between demand and supply. And it’s already doing it in clinical decision support. For example, there is a company called Aidoc that allows radiologists to identify life-threatening pathology on brain scans that potentially they may have missed. There are AI-enabled mammography tools that can predict occurrence of breast cancer before it even happens.

There is also an investigational AI tool that allows clinicians to predict the onset of Alzheimer’s dementia before any cognitive decline. As a personalized medicine and longevity doctor, this is where I see the biggest impact. Transitioning into clinical decision support, I predict it will make the “N of one” personalized medicine a standard type of medicine. Eventually, we will abandon our focus on large populations because AI will enable us to address population health differently. We’ll be able to leverage small data, that N of one, to build much more enriched phenotypes. Populations as we know them for investigations and healthcare will be redefined through AI, and that will be a huge impact.

Q: That’s awesome. Thank you, Regina. This has been a very interesting conversation. Really appreciate it. Any other last comments? 

Regina: Maybe just a quick note to anyone listening who might be a physician, nurse, nurse practitioner, or anyone in healthcare with a medical affiliation. If you’re thinking, should I be doing it, should I not, should I jump into this entrepreneurial route and see where it takes me? There are no guarantees, but if you are one of those people, the best time was 30 years ago. The second-best time is now.

————-

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI and the Future of Longevity-Driven Personalized Care

Season 6: Episode #177

Podcast with Dr. Regina Druz, Founder and CEO, Holistic Heart Centers

AI and the Future of Longevity-Driven Personalized Care

To receive regular updates 

In this episode, Dr. Regina Druz, Founder and CEO at Holistic Heart Centers, shares her journey from conventional hospital-based cardiology to leading the charge in personalized precision medicine and longevity-focused care. She explains why optimizing health is the cornerstone of extending lifespan and how digital health innovations must deliver value for patients, clinicians, and caregivers—improving outcomes, reducing burnout, lowering costs, and meeting regulatory demands.

A pioneer in telemedicine, digital devices, and AI tools such as ambient scribes and large language models, Dr. Druz examines the opportunities and challenges of Agentic AI in transforming healthcare workflows. She envisions a near future where AI goes beyond administrative tasks to provide advanced clinical decision support—predicting and preventing conditions like Alzheimer’s and heart failure years before symptoms arise.

For Dr. Druz, the “N-of-1” approach—tailoring care to each individual’s unique biology and circumstances—will become the new standard, redefining population health through truly personalized care. Take a listen.

Video Podcast and Extracts

About Our Guest

Dr. Regina Druz is not just a cardiologist — she’s a trailblazer in the movement toward precision-based, longevity-focused medicine. As CEO and founder of Holistic Heart Centers™, she is redefining heart health through a cutting-edge fusion of integrative cardiology, functional medicine, and digital innovation.

With a medical degree from Cornell University, board certification in cardiology, and advanced training in functional medicine, Dr. Druz brings scientific depth and systems-thinking to every patient encounter. Her proprietary program, Fit in Your GENES®, personalizes care through genetic and metabolic profiling, offering clients a transformative roadmap to vitality and healthspan extension.

After earning a dual Executive MBA and Master of Health Policy and Research from Cornell, she went on to lead value-based cardiology transformation at the national level. Today, she applies that strategic vision to build scalable models of care that are personalized, proactive, and precision-driven.

Driven by data, powered by purpose, and rooted in compassion — Dr. Druz helps patients and healthcare systems move beyond risk management to true health optimization.


Q: Hi Regina. Welcome to The Big Unlock Podcast. I am Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting. It’s so nice to have you on the podcast, especially since you are a practicing physician. Would you like to introduce yourself to the audience? 

Regina: Well, Rohit, thank you so much for having me, especially since I am a practicing physician. I’m not a technical founder or someone in the data world full-time.

For you listeners, I am Dr. Regina Druz. I’m a board-certified cardiologist since 2001. I’ve gone through all the traditional cardiology training and worked in hospital settings, academic settings, and private practice. Along the way, I went down the entrepreneurial route, which led me to personalized precision medicine, longevity medicine, and rethinking what cardiology should be. One of my colleagues calls it “comprehensive cardiology.” It’s about redefining what I can bring to patients and how they can benefit beyond traditional, expected care.

Q: That’s very cool, Regina, to know that you are now on the path of your entrepreneurial journey as well. So tell us, what attracted you to healthcare in the first place? How did it all start?

Regina: Good question. My parents are not physicians, but I grew up with amazing role models. My aunt and her daughter, my cousin, were the original power women, though the term didn’t exist then. Both were physicians—obstetrician-gynecologists—and were excellent at what they did. My aunt, after her education, was asked to go to an underdeveloped country to help build healthcare and improve maternal mortality. Many women at that time were dying in childbirth, and she brought in new practices that made a huge impact.

They were inspiring role models. Since I was young, I said, “I’m going to be like them. I’ll be a doctor, I’ll be strong, I’ll cure the world.” My father, an electronics engineer, pushed me toward technical fields, and I enjoyed science. But biology really grabbed my attention. The rest was conventional: medical school, residency, fellowship.

I didn’t end up a gynecologist, which disappointed my family a bit. They said, “Oh my goodness, you’re choosing to be a cardiologist?” But I said, “Women can do cardiology too.” Luckily, more women have entered cardiology over the past 20–30 years, and specialties once dominated by men are now more welcoming. Women are making their mark. That’s me in a nutshell.

Q: That’s a very cool journey, Regina. So you talked about something in your introduction which caught my attention around personalized medicine and longevity. So please tell us like what does it all mean and how’s it coming together?

Regina: That’s a great question, Rohit. Maybe I’ll take you back to some of my more traditional cardiology days. When I was working in a hospital setting, I was responsible for an area involved with cardiac imaging. We have various procedures to image the heart, understand how it functions, if the blood vessels are open, if the valves are doing okay, and if we can foresee the future and understand what’s going on. My particular area was nuclear stress tests. Patients typically had to exercise on a treadmill as part of a stress test. For those who couldn’t exercise, we used a chemical stress test, but the majority exercised on a treadmill. We would inject a little bit of radioactive material to see how blood flows into their heart and determine if their heart is healthy.

What came out of it is that as doctors, we were a bit biased. We would expect younger people to do better, and that older people would not do as well. But 20–30% of the time, we would get the opposite—an older person who did much better than expected, and a younger person who did very poorly. This started my journey into personalized medicine. I started to ask if there was a pattern—what are the older people doing to preserve this ability into older age, and what are the younger people doing, or not doing, that actually takes away from what we think they should be able to do, cardiac-wise and physically?

I started asking patients questions that weren’t part of our standard intake. Do you exercise at home? Do you garden? Do you travel? What do you like to do? What gives you purpose? I looked at other physicians who introduced this idea of “n of one,” of personalized medicine. There are reasons, systems biology, root causes driving health and longevity, and also driving disease. It’s not standardized; it’s not a population-based metric. It’s literally the N of one.

That piqued my curiosity, so I decided that the best way to address it was to take what I know in cardiology and bring it into a personalized medicine approach. The best fit for it was integrative and functional medicine, where we could expand our lens and look beyond just hard numbers—like cholesterol, blood pressure, and medications—and ask why levels are elevated, and what we can do lifestyle-wise to optimize health. Optimized health is a major contributor to longevity. Physical health, cardiovascular health, brain health, and systemic health are really the foundation of any longevity equation. You can’t talk about longevity if health isn’t optimal.

That was the beginning of going off the beaten path. My colleagues thought I was crazy because they could not understand it. They said, you have great credentials and roles. At that time, about ten years ago, there was no room in the institutional setting for this. There could have been some departments inclined toward integrative or complementary medicine, but nothing institutional. That meant going on my own, right as medicine was beginning to consolidate. People said I was insane and would do very poorly. I opened my first tiny practice with about three patients in an area saturated with cardiologists. Even back then. Today, it’s exponentially so. I’m here to tell you this works, and this was not only a huge benefit to my patients, but it was a benefit to me.

Q: That’s awesome, Regina. And I know you are very interested in all the new technologies coming our way. In any podcast these days, we have to touch upon AI. How do you look at AI and digital health from the lens of cardiology? What does it mean to you, and how do you see some use cases from a physician, patient, and caregiver perspective? How does it all play out in your world?

Regina: It’s a great question, Rohit. I was an early adopter, so back then there weren’t as many things available to us. Right now we have so much more. In any digital health domains, in cardiology or any specialty, you have to ask how they benefit a patient, and how they help doctors, patients, and nurses to do the right thing without burning out, saving on cost, and staying compliant with regulations.

I started with telemedicine. I was an early adopter, and since my practice was personalized, telemedicine is a great tool. It gives patients a lot of access, but it has a major deficiency: you’re not getting a physical exam. You can’t listen to a patient or do those things. I needed their blood pressure, electrocardiogram, and a couple of other measures to assess if they are okay. This led me to explore digital tools available—there are quite a few. For example, a company called AliveCor created a device you could clip onto an iPhone, and by putting two fingers on metallic plates, it would record a single-lead electrocardiogram. It wasn’t a full EKG, but it was the beginning.

Other companies like Omron and Withings came out with Bluetooth-enabled blood pressure cuffs, letting patients check their blood pressure and transmit the information to me. For the first time, with telemedicine adoption, I wasn’t blind anymore. When COVID came and in-person visits were canceled, I wasn’t stuck. I already had the telemedicine platform and some of these tools.

Now it’s even more diverse. I routinely use the tools from these companies. Now we can do a Bluetooth-enabled 12-lead electrocardiogram with AliveCor—no traditional machine needed, just a small remote controller with a button. Cardiac and vascular ultrasounds now have devices like Butterfly IQ, which has ultrasound on a chip that connects to a phone or iPad, providing diagnostic images affordably.

Digital devices first went to practitioners and are now available to patients. Patients use Apple Watch, Withings, Fitbits, and other trackers. Suddenly we have overwhelming streams of data. Now, AI has come into the picture. Patients are becoming “citizen patients”—they investigate themselves, upload their data into large language models, and get outputs. They have agency to do this, even if they can’t always tell whether the output is correct.

These data streams are becoming routine in medical practice. Places like Mayo Clinic use large data repositories and AI tools to analyze electrocardiograms and predict heart failure years before symptoms appear. This is a huge opportunity. We could work with high-risk individuals preventatively, sparing them clinical heart failure. Once someone has their first heart failure episode, five-year mortality is 50%. Imagine if we could be ahead of this curve.

We are evolving from curiosity to clinical implementation and, hopefully, to clinical competency—making this standard care, not just a nice-to-have. Regulatory bodies recognize the value of these devices. Medicare, for example, pays for remote care monitoring (RCM), usually reserved for higher-risk patients and accomplished through digital devices and AI interfaces. They allow us to identify what’s happening—a sort of third eye.

Q: That’s pretty deep usage of AI and digital devices in different ways, Regina. One other thing—I know you mentioned large language models. Another thing that’s become very popular is AI coding tools. We were just chatting before the podcast, and I have several physician friends experimenting with such tools. So tell us your experience. You mentioned an article too; tell us more about what you’re seeing in this space. 

Regina: This is very interesting because when ChatGPT became a household name, I said, okay, let me give it a try. At the time, I was studying for my boards. Cardiology boards have different ways to maintain certification. One newer way is that every year you do a small cardiology knowledge exam. It was time for my exam, and I was studying using traditional stuff from the American College of Cardiology, but some explanations to questions left me wanting more. So I started putting those questions into ChatGPT, and it gave me deep, nice, long explanations that covered some of my blind spots. That was interesting. I think large language models, when they don’t hallucinate, are great educational tools. You can constrict them to look at specific journals or guidelines.

But the real breakthrough for me as a practicing clinician came from ambient AI scribes. They became indispensable in my practice. There are several companies; I personally use one called Heidi Health, a startup from Australia. Most people think ambient AI scribes just catch conversations and save time on notes, which is true, but there was something else—a positive externality. The structure of the AI scribe allowed me to generate versions of notes, including one I could send as a message to patients via patient portals. This summarized next steps clearly—what they need to do and how. Instead of reinventing this, after some tinkering, I generated a template I liked. This enhanced my patient care meaningfully by adding another touchpoint, another opportunity for engagement. It also helped me not have to remember everything but to clearly outline the next step.

In personalized medicine and longevity health optimization, this requires a lot of participation. It’s very different from traditional medicine where doctors just tell patients what to do and wait for them to come back. Here, it’s the opposite; you need to reach out regularly. The AI scribes gave me that ability to be efficient and effective and to “excite and delight” patients with better communication.

As a clinician entrepreneur, I am also experimenting with Agentic AI. Some experiences are helpful; some are questionable. One unsettling issue, raised by AI experts like the CEO of Tropic, is that AI is a black box. We lack full visibility into how it generates answers, especially with agent AI. I asked it for a simulation on a complex patient with cardiac and immune issues, including all parameters we know. The AI produced a great output with references and did not hallucinate. My initial hunch was correct, but I wanted to know how it built the case. In medicine, we use frameworks for diagnosis, workup, and prognosis—check and balances learned from real outcomes. That’s where AI’s black box presents challenges.

Whether it’s LLMs or chatbots or more complex agent functions, we are in uncharted waters. We will use them going forward, but we need more visibility into their processes for trust and safety.

Q: Of course. Regina, I think we hit on something during our pre-podcast discussion about the digital divide. You said people with high agency will propel ahead using such tools. Could you explain your thought process behind that? 

Regina: Great question, Rahi. The digital divide often comes up with digital tools like wearables or telemedicine platforms. We have to ask whether certain patient groups will face barriers. Older patients may not be technologically savvy enough to navigate telemedicine or connect Bluetooth-enabled devices like blood pressure cuffs. They might struggle with mobile apps or synchronizing devices. Plus, healthcare privacy is heavily regulated.

Traditionally, the digital divide affects older patients, those with cognitive issues, non-English speakers, and those who can’t afford or access these tools. But I believe another digital divide is forming. Recently, I read a Wall Street Journal piece about AI tools that almost anyone can access at a free level. To truly benefit, users must be “high-agency” individuals—able to instruct the tool, understand its limitations, refine outputs, and keep moving forward.

I see this with my patients. Those with high agency get more information, more touchpoints, and a very different experience managing their health compared to those less inclined to use these tools. Physicians sometimes reinforce this divide. One colleague, Dr. Kim Williams, former ACC president and lifestyle medicine champion, uses ChatGPT as part of his team. He inputs patient scenarios—not for medical advice but for cultural context—to help patients transition to healthier diets without overwhelming them.

Q: That’s awesome. As we close, Regina, looking into your crystal ball over the next 3–5 years, what exciting things do you see coming our way? 

Regina: It’s an interesting one because I ask it to myself very often. In the physician community, there are a lot of voices who say AI is going to replace doctors. And then, from the tech world, there are predictions like no more radiologists.

Of course, there are other voices that are more introspective and say no, AI is not going to replace doctors. To me, it’s very clear that we are going to see in the next five years a rapid emergence of agentic AI in all verticals of healthcare. It’s going to take care of mundane tasks like pre-authorizations, appointment scheduling, and supply chain management.

Then it’s going to really make its mark in staffing decision making, especially when calibration is needed between demand and supply. And it’s already doing it in clinical decision support. For example, there is a company called Aidoc that allows radiologists to identify life-threatening pathology on brain scans that potentially they may have missed. There are AI-enabled mammography tools that can predict occurrence of breast cancer before it even happens.

There is also an investigational AI tool that allows clinicians to predict the onset of Alzheimer’s dementia before any cognitive decline. As a personalized medicine and longevity doctor, this is where I see the biggest impact. Transitioning into clinical decision support, I predict it will make the “N of one” personalized medicine a standard type of medicine. Eventually, we will abandon our focus on large populations because AI will enable us to address population health differently. We’ll be able to leverage small data, that N of one, to build much more enriched phenotypes. Populations as we know them for investigations and healthcare will be redefined through AI, and that will be a huge impact.

Q: That’s awesome. Thank you, Regina. This has been a very interesting conversation. Really appreciate it. Any other last comments? 

Regina: Maybe just a quick note to anyone listening who might be a physician, nurse, nurse practitioner, or anyone in healthcare with a medical affiliation. If you’re thinking, should I be doing it, should I not, should I jump into this entrepreneurial route and see where it takes me? There are no guarantees, but if you are one of those people, the best time was 30 years ago. The second-best time is now.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Redefining Senior Living – Michael Hughes on Innovation, Social Determinants of Health, and the Future of Aging Care

Redefining Senior Living – Michael Hughes on Innovation, Social Determinants of Health, and the Future of Aging Care

The senior living industry is undergoing a quiet revolution. What was once viewed primarily as housing for older adults is transforming into a holistic health and wellness ecosystem, where housing is just one part of the story. Michael Hughes, Chief Transformation and Innovation Officer at United Church Homes, is at the forefront of this change — driving initiatives that combine affordable housing, healthcare partnerships, advanced technology, and human-centered care models to better serve an aging population.

In a recent episode of The Big Unlock podcast, Mike shared his perspectives on where the industry is headed, the role of social determinants of health (SDOH), and why co-creation and prevention will define the next chapter of senior living. His message is clear: the future will be more connected, more personalized, and more prevention-driven than ever before.

From Housing Providers to Health and Wellness Partners

United Church Homes operates more than 100 properties across 15 states and two tribal nations, encompassing affordable housing, life plan communities, skilled nursing, and independent living. But Mike believes the industry’s future isn’t about the physical buildings — it’s about integrating housing with wraparound services that help older adults remain healthier, happier, and more independent for longer. He states that, “The future of senior living is transitioning from housing providers to health and wellness providers with housing at its core.”

This shift requires a mindset change. Instead of focusing solely on residents who can relocate into communities, United Church Homes is building partnerships with CMS programs, managed care organizations, and local service providers to bring services directly to where people live.

Their decentralized, hub-and-spoke model allows the organization to support older adults who may never move into a senior living facility but still face challenges in managing health, safety, and daily living. For Mike, this approach is not just about expanding reach — it’s about meeting people where they are and creating sustainable models for the future.

Service Coordination + Social Determinants = Fewer Hospitalizations

One of United Church Homes’ most impactful innovations is its service coordination program in affordable housing communities. Funded through HUD, these coordinators assess residents’ social determinants of health — the non-clinical factors such as transportation, food security, financial stability, and home safety that account for roughly 70% of health outcomes.

The impact is measurable and remarkable. Out of 3,200 affordable housing residents with service coordination, only 50 moved into skilled nursing facilities and 110 experienced unplanned hospitalizations over a 15-month period. For a population often living with multiple chronic conditions, these numbers are exceptionally low.

Mike credits this success to a trust-based, relational care model. Coordinators do far more than connect residents to resources like Medicaid waivers or home health agencies — they also provide emotional support and guidance during health crises. He says, “Nobody takes their pills because they like how they taste. We build care plans around personal goals and motivations.” This focus on personal motivation — whether it’s wanting to keep a beloved pet, maintain a garden, or attend a local art exhibit — turns care into a collaborative process rather than a compliance exercise.

By unbundling service coordination as a standalone service, Mike sees potential to integrate it into managed care programs, employer wellness benefits, and long-term care insurance models — particularly for high-cost, high-need populations.

Using AI and Machine Learning for Preventative Wellness

While technology is often positioned as the silver bullet for healthcare challenges, Mike approaches it with a clear focus on prevention and practicality. His innovation strategy prioritizes tools that generate actionable insights and measurable outcomes, rather than chasing every new gadget.

Machine learning currently tops his list, especially for analyzing the effectiveness of community referrals and identifying which services truly improve health outcomes. By combining clinical and non-clinical data — such as functional status, home safety, and caregiver availability — United Church Homes is building predictive models that can guide earlier interventions and strengthen value-based care partnerships.

Some of the most promising solutions are also the most cost-effective. For example, Mike is testing RFID tags in shoes to monitor mobility patterns, replacing more expensive and complex sensor systems. This approach aims to capture 60% of the data that drives 80% of the insights — at a fraction of the cost.

He also sees potential in agent-based AI for automating routine but time-consuming tasks, such as arranging transportation after a doctor’s appointment or processing prescription renewals. If done right, this could free human staff to focus on relationship-based care, where the greatest value lies.

Co-Creation Through the Entrepreneur-in-Residence Program

For Mike, successful innovation in senior living starts with deep immersion in the environment you want to improve. That belief inspired United Church Homes’ Entrepreneur-in-Residence program.

Participants in this program live in a senior living community for two weeks. The first week is spent shadowing staff to understand operational realities; the second is a “choose your own adventure,” where participants adopt the persona of a new resident and experience daily life firsthand.

This immersive approach helps innovators fall in love with the problems before proposing solutions. It reveals nuances of resident experience, staff workflows, and organizational culture that would be missed in a traditional consulting or product design process. Mike says, “Unless you co-create with the people you aim to serve, you have no load around your system.”

The program has already sparked collaborations and produced solutions that are better aligned with resident needs, easier to implement, and more sustainable. Mike hopes to see other senior living providers replicate this model as a best practice for human-centered innovation.

The Future: Decentralized, Purpose-Driven, and Prevention-Focused

Looking ahead, Mike envisions a more distributed model of senior care — one that extends far beyond the walls of any single facility. This future will be supported by technology, community partnerships, and purpose-driven engagement.

One concept gaining traction is social prescribing — where healthcare providers “prescribe” community-based activities such as nature walks, museum visits, or volunteer work to combat loneliness, boost mental health, and encourage physical activity. Countries like the UK and Canada have embraced this approach, and Mike believes it could play a major role in U.S. aging services as well.

At the core of his vision is the idea that purpose is as important as care in later life. Whether it’s spending time with grandchildren, tending a garden, or pursuing a creative hobby, these motivations should anchor care plans and guide service delivery.

Mike also emphasizes the need to remove daily life frictions — from home maintenance challenges to transportation gaps — so older adults can maintain independence and dignity. This, he says, is where innovation should focus its energy: creating systems and services that empower older adults to live abundantly in the place they choose.

Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation

Season 6: Episode #176

Podcast with Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center)

Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation

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In this episode, Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center), shares his vision for scalable digital health transformation. He outlines a proven framework focused on patient engagement, clinically integrated care, and remote patient monitoring—strategies that have already driven an 18–20% increase in online scheduling and improved outcomes in preventive care campaigns.

Inderpal also reflects on how a chance project in biomedical informatics sparked his passion for digital transformation, leading to pioneering work in digital pathology, remote monitoring, and digital front door solutions. He explores the promise of ambient documentation in reducing clinician burden and enhancing satisfaction, and addresses the persistent challenge of integrating EHR systems with third-party tools—stressing the importance of seamless integration for meaningful impact.

He also discusses the potential of digital twins as a game-changer, shares lessons on building agile, consumer-focused digital teams, and weighs in on how GenAI and agentic automation are poised to reshape care delivery. Take a listen.

Video Podcast and Extracts

About Our Guest

Inderpal Kohli is a mission-driven CIO with over 25 years of experience transforming complex healthcare systems through digital innovation, AI enablement, and operational excellence. Kohli has extensive expertise in strategic planning and deploying enterprise information systems to support centralized clinical and business operations. Most recently he was the Vice President of IT and Chief Information Officer at Englewood Health, where he led all technology aspects, guiding digital and AI transformation strategies for the health system, including its acute care hospital, a network of over 100 locations, and more than 700 physicians in the network, all connected through a single electronic medical record system. Leading a high-performing team of over 160 members and managing a $50 million budget, significant initiatives at Englewood include a digital transformation strategy and execution, an enterprise cybersecurity program, the deployment of the first in any hospital, a unified communications architecture on the Zoom platform, the expansion and enhancement of Epic, and a cloud-based Enterprise Imaging solution.

Before his tenure at Englewood, Kohli was an assistant vice president at the Hospital for Special Surgery in New York City. There, he was responsible for overseeing the implementation of various enterprise information systems, including Epic. Furthermore, Kohli played a key role in pioneering an advanced digital pathology solution that enabled integrated diagnostics by capturing, sharing, and correlating high-resolution digital images of glass laboratory slides—marking a first in the country.

Kohli also served as the information systems manager at Columbia University Medical Center. During this time, he played a key role in designing and developing a flexible information infrastructure focused on clinical research, including an epidemiological study that contributed to one of the largest genetic material databases in the country.

Beyond his professional achievements, Kohli actively participates in the healthcare community as a sought-after panelist and speaker at various healthcare and technology conferences. He is also a prolific contributor to print and digital media outlets. He was recently honored with the 2024 NJBIZ Leaders in Digital Technology Award.

Kohli holds a master's degree in Technology Management from Columbia University and a Bachelor's degree in Computer Science from India. His dedication to education is evident through over a decade of teaching experience at the master's level. At Weill Cornell Medical College in New York, he led a curriculum focused on healthcare informatics, passing on his extensive knowledge to the next generation of IT professionals.


Q: Hi Inder, it’s great to have you on the podcast. I am Rohit Mahajan. I’m the managing partner and CEO at BigRio and Damo Consulting. This Big Unlock podcast was actually started by Paddy Padmanabhan, who founded and started Damo Consulting. I’m very happy to carry on his legacy. He’s pretty well known in the healthcare circles. I’m sure you’ve probably met him at one of the conferences as well.

So, super excited to have you here Inder, and over to you for your introduction.

Inderpal: Thank you, Rohit. And yes, you bring up Paddy, and who doesn’t know him and what a great individual he was. I’m glad I had the opportunity to work with him. Thank you for this opportunity. I’ve been in healthcare technology space for over two decades now, consistently working on innovation and digital transformation across complex organizations. I have very good experience working with some of the best organizations in the area. I landed in healthcare at Columbia University Medical Center, had a long stint at HSS in New York, and then Englewood Health in New Jersey. I’ve gained experience by rising up the ladder over these years and have a good grasp of the entire continuum of healthcare from a provider and patient delivery perspective. I’m really excited to talk about what my experiences have been and what your viewers are interested in. 

Q: Absolutely. Inder, like you said, you got started in healthcare over 20 years ago, and you worked with some of the finest institutions. You are well regarded as a healthcare leader in the space. Tell us more: what attracted you or how did you gravitate into healthcare? 

Inderpal: The first few years of my career, I worked in India, Southeast Asia, and the Middle East, mostly around banking and financial sector. Even in the US, I had a stint working with CitiMortgage for almost two years, and then the project ended and we were looking for a new project. I landed a new project at Columbia University Medical Center. I did not know at that time how lucky of a break that was because I landed at the biomedical informatics department, a pinnacle of informatics research back then and even today. That’s where I first entered healthcare by accident, but then decided to stay in. The clinical research part, clinical trials management—all that was new to me but interesting. We also developed solutions which we deployed at New York Presbyterian Hospital for patient care. That was my first exposure to what bench to bedside looks like, and that really solidified my interest to stay in healthcare.

I was part of the Epic transformation journey for many years, as HSS grew and made collaborations with other hospitals like Stanford in Connecticut, Florida Tenant Hospital, and New York Presbyterian. I was part of clinical integration and external integration workflows. It was a great stint at HSS, and then an opportunity at Englewood to manage all aspects of IT as CIO. This broadened my horizons further; application was my home base, but I also took over cybersecurity, infrastructure, and networking, led modernization efforts around infrastructure, storage, servers, data centers, disaster recovery, and built the cybersecurity program. This gave me a holistic experience, and that has been my journey—23, 24 years in strictly healthcare organizations.

Q: That’s awesome. So could you please share with us in the aspects of this journey with us in terms of what are the digital health programs that you kind of like, were very close with and you, you kind of have oversee, and what have you been your current priorities? Any recent deployments and any outcomes that you have?

Inderpal: Yeah. So my digital health or digital transformation journey really started at HSS. HSS was a two-part, right? There was a huge emphasis on operational efficiency because we ran 39 ORs. The more efficiently we ran ORs, the better it was for patient care, for business, for the organization.

So we started with this whole concept of a command center, a digital clinical command center and digital twin, which was a very new concept back then, to really look at and run models on operational efficiency, clinical efficiency, clinical care, and outcomes. That journey started there for me.

In parallel, HSS was also doing what was typical digital transformation of patient outreach, patient engagement, and front doors. Then COVID came and kind of brought a screeching halt to that journey. But lucky enough for me, I was also working in parallel on a very innovative solution for digital pathology.

As you know, radiology has been digital for ages now. We don’t even know what film x-ray looks like, but pathology is still on glass slides and microscopes. That is one thing I wanted to change, and I found the right champion in my chief of pathology. Together, we put through a program, almost a year and a half of development with Epic, our PACS vendor, the scanner vendor, and my team, to develop a digital pathology solution, which wasn’t FDA approved then, so we couldn’t use it for primary diagnosis. But then they applied for FDA approval and once FDA approval came, we were ready to hit the ground running. You talk about outcomes—this is where the outcomes were significantly faster because of the situation we were in.

During COVID, within a year, 70% of all pathology cases were being diagnosed digitally. Huge change for an organization or for a group of physicians who have always been tied to the microscope. It also offers better patient care because now the radiologists, the pathologists, the surgeons, the infectious disease doctors all can correlate images—both radiology images and other ologies—which was not the case before; they had to sit across a double-headed microscope. And of course, for teaching, for research, for second opinions. And then, back in 2021, we did not have it, but now all of the tools are layering on top of it, because digital pathology lends itself to a lot of AI tools. It’s about cell counting, pattern recognition, quality of diagnosis—all of that could be improved and normalized across the institution with the tools. So a really great program and I’m very proud of it, and that happened to be the first in the country back in 2021.

And then I carried on the same digital journey when I joined Englewood. We initiated our whole digital transformation strategy. It was a three-pronged approach: patient engagement and patient self-service; clinically integrated care—because Englewood is a large physician practice organization, 700 physicians in practice across multiple specialties—so we feel it’s much better for us to take care of a patient and we can take care of the patient much better compared to sending the patient outside because of the availability of all data and historic diagnostics for the patient within our system; and then the third piece of that was when the patient is not with us—how do we continue to manage the patient remotely?

Since you talk about outcomes, I think that’s most exciting for the team. As part of our digital front door strategy—the typical patient self-scheduling, rescheduling, request for services—we saw about 18 to 20% increase in online scheduling of appointments, and that number was consistently rising.

The big challenge with that is not technology. It’s aligning the physician organization to open up schedules for patients. Then we ran campaigns for patients. This was post-COVID. A lot of preventive care was put on a back burner by patients, and those campaigns were delivered digitally through Epic’s CRM product. So really no manual assembly and actionable text messages. For first-time annual overdue screening mammograms, we saw a 21% success rate—huge in this case. For first-time screening, we saw 6%. So you’re reaching out to your eligible patient population, and once you set the campaign, it’s really in auto mode. From that point, the patient gets a text message which is actionable: schedule an appointment, move on. Then we extended this to colorectal screening and lung cancer screening. All of them saw at least 7 to 10% success rate. It looks like a small number, but we were doing these campaigns via paper and were not seeing anywhere close to this number. A 10% success rate is huge versus not getting anything.

Another aspect I talked about was when the patient is not within our four walls. So how can we take care of them? We initiated a remote patient monitoring solution integrated with Epic. That’s key—so the physician has the data back in Epic. That program saw success. It was for blood pressure monitoring initially, and 84% of the patients who were part of the program within the first six months saw better numbers—not on any new meds or anything, but with active monitoring, care coaching, and the new technology. We saw a trending line which was better than before—positive trending for those patients. So early success factors there.

Then, this was all around patient care, and we also started working towards physician burden because they’ve been overburdened with all the technology we have laid out. So ambient charting was one of the products we rolled out in our physician offices, and ambient charting has a three-pronged benefit: for physicians, it’s timely documentation, real-time documentation, and being able to spend more time with the patient. It saves a few minutes in an appointment. And what does it mean? It means you’re not staying up late and using your pajama time to do documentation. We saw a 40% reduction of that time for the physicians who were using ambient charting.

The other benefit for ambient charting is better coding. Englewood was at the top quartile to begin with, so we didn’t see better results there, but I read statistics the other day at a hospital in Iowa that was saving an average of $13,000 per physician per year because of the ambient charting product, and most of the recovery was with better coding and charging. HCC coding resulted in $10,000; E&M coding resulted in $3,000. Huge number, and a huge physician satisfaction, even patient satisfaction, because the physician is talking to them. We saw those benefits.

Then we worked on a lot of other back-office functions. We’ve all been very fast at reaching out to physicians via MyChart messages. That burden is huge on physicians with everyone sending those messages. So we put in an AI tool—augmented response technology in Epic—to draft and generate a response to the patient based on the question, chart history, and what the patient has asked in the past. That is again an efficiency function. A quick chart summarization—you’re seeing a patient after a long time; you don’t need to click through the chart— a quick chart summary will come up with all the pertinent things. Then we also moved back-office functions like denials and appeals letters and prior authorization. This is a combination of RPA and some generative AI, but the outcome is important for all of these.

Q: That is cool to know. So obviously, during all these initiatives, there would be challenges in building and delivering the digital capabilities—whether technology, people, resources, or process. What are some of your learnings there, and what could you share with the audience on how you surmount these challenges?

Inderpal: Challenges are many. I will classify them as technology challenges, process challenges, and resource challenges. Technology challenges, for the most part, we are able to overcome, but what we call technical debt sometimes gets in the way. Technical debt is not necessarily obsolete operating systems and obsolete technology. Sometimes technical debt could also be in the form of how a modern system was built and deployed when we didn’t plan for digital transformation a few years later—how appointments were established, appointment types, or departments were established in a solution. All of those build decisions, if they were not planned with a digital lens, will require us to go back. And that happened with us. We had to go back and fix it. It wasn’t about a technology solution.

Sometimes the technology debt comes in if your data architecture is not where it needs to be—you don’t have your right data definitions. We want to make data-driven decisions, and for that, we need to be aligned and have confidence around the organization’s data. That’s one challenge for most organizations.

Then the other is moving your organization—executive and operational leadership—onto an agile process. The first thing I prepared my organization for was: be prepared to fail occasionally. Everything will not be a success because we are not dealing with an ecosystem like big vendors like Epic and Cerner, where it’s a proven thing and it’s a 12–18 month project and we’ll have success at the end of it. We are dealing with an ecosystem where there are a lot of new players in the market. They have promise; some will pan out, some may not. But the good thing is that we will not wait 18 months for the outcome. We will be agile. We’ll try for three months, measure the KPIs, and make a decision. That’s a mindset change for an organization. Once a project is authorized, it’s difficult to walk away from it. That’s one challenge.

Then resources. We are all short-staffed and our resources have a full plate, but are very dedicated and specialized. Now, suddenly in digital, we’ve been used to working in a controlled environment until about five or six years ago. We know the clinicians, how they will use systems; we map their workflows; we build a system according to their requirements. But now you’re dealing with an uncontrolled environment of the patient. You don’t know how they will use it. Suddenly the UX design, the patient engagement piece—your teams have to learn about it, think about it, and the environment they cannot map. They can only predict as a consumer how they will use it. That is a big challenge for resources—not necessarily just a resource gap, but also the mindset change for your teams.

So most organizations are building separate digital teams which have more ear to the ground in terms of what consumers are looking at and are also looking at other industries and how they’re utilizing. I’ll end with one thing: every patient understands—me and you—that seeking healthcare is more complicated than ordering a meal or hailing a ride. It doesn’t mean we don’t want that with healthcare. Deep inside, we all want that kind of convenience, and I think that’s the big challenge on the other side of providing that level of convenience, which is unfair to say because it’s a lot more complex—but still.

Q: That’s true. That’s a good vision, Inder. Moving on to another topic, I wanted to touch upon the role of EHR versus non-EHR platform choices and what that means in the healthcare setting. You make a lot of decisions; you’re grappling with a complex system with lots of enterprise software. Any thoughts there?

Inderpal: I would say this—I’ll answer on both sides. First, my responsibility and everyone else’s is to maximize our investment. If I’ve already invested in a solution—and it’s not just dollar investment, but team, resources, and knowledge investment—and there’s a function offered out of an EHR solution, it’s better because it’s already integrated in the workflow. It will not require relearning a new system and may deliver the same value. That’s the good part. I’ve increasingly found it often turns out economical because the base is all there. The downside is being bound by an EMR/EHR vendor’s product life cycle. To be fair, they have a much bigger responsibility managing the entire hospital: clinical documentation, compliance, patient safety, efficiency. They consistently improve their product as that’s their focus. Customers ask why their million-dollar product doesn’t do certain things. They add modules. They are torn where to focus. Their primary focus has to be patient safety and core system functions. That tussle always exists and may or may not work for me, depending on my timeline.

If I go third-party, we all have been there. Best-of-breed solutions focus on one to three matching functions—often done better—but then integration with EMR is essential, or there’s no utility. There’s added cost, team training, etc. It depends where you are on your journey. Every organization is different. If you absolutely need, say, a patient campaign function with clear ROI, it makes sense to invest. That investment can be interim until your EMR adds a similar solution or maybe never. I think the value is timely implementation and deriving clinical and business value from the solution. If your EMR vendor’s timeline aligns, it’s a good choice. More often than not, the functions you need are in third-party solutions and need evaluation for longevity and business sense. I think both have significant roles and will continue to.

Q: That’s a good point. I like how you said that if a third-party solution integrates with the EMR/EHR, it has more value. 

Inderpal: Oh yeah, that’s the sign nowadays. Otherwise, no technology leader would entertain a standalone solution. 

Q: Yes, integration is key. Now, coming to the fun part, no podcast is complete without AI, GenAI, LLMs, and all these agentic AI things. Where do you see the future of digital and AI transformation? What are some things you are currently or looking to focus on in the future?

Inderpal: Sure. I was listening to someone the other day say that, like everything else, AI had a hype—blockchain had a hype, everyone had a hype. It won’t do everything for everyone, and I agree at a high level. But it’s here to stay and scale. Healthcare did not wait on the sidelines. We all wanted to jump in, even if limited, and most healthcare systems use at least some tools in the space. I use a few; everyone does. Right now, we’re doing what I call low-risk patient engagement, self-services, scheduling—all of those things. That’s how you want to dip your toe in the water. For my GenAI-based virtual agent, initial use cases are appointment scheduling, rescheduling, info requests, payments—no clinical data. That will continue to evolve; this is normal in other industries. I was trying to get services from Verizon yesterday; their chatbot and virtual agent were great—I didn’t need to talk to a person. It’s everywhere; we will get better. Integration and alignment are key to offering those services to patients, so that’s here to stay.

Ambient documentation is here to stay and will be all-pervasive. It’s already beyond physician offices—to inpatient rooms, nursing. Eventually, ambient and dictation systems will merge, become redundant as separate systems. Ambient will continue evolving over 12 to 18 months. Workflow alignment will come. Technology is already aligned and giving benefits; workflow alignment is required to best use it and get outcomes. My long-term guess is that in 4 to 6 years, clinical use of AI will be a differentiator.

The pinnacle will be personalized medicine. We talk about it now—dosage based on population sectors. Personalized medicine is probably the pinnacle, but before that, point-of-care recommendations and decision-making will be reality in 4 to 7 years. Agentic and agent-based AI will take root in many back-office functions, which have many manual processes that can be automated. RPA did some, but now agent-based AI will ramp up.

Digital twin technology is cost-prohibitive today but could be a game changer for personalized care and letting health systems try things rather than run long pilots. If widely adopted in healthcare solutions, digital twin could speed design changes and implementations faster than parallel testing and pilots.

Q: True. We’re seeing a lot in the agentic AI space, personally and at BigRio, with clients including voice agents. 

Inderpal: You’re right. We did omnichannel virtual agents—voice, text, and web—with Zoom, Epic, and Amelia. I saw your agentic AI webinar recently; very cool. I personally haven’t used agentic AI but would like to try it. Sometimes it looks too good to be true, but it’s happening in real time and performing roles. I wish to try it in the next months or years.

Q: Awesome. Thank you for sharing your thoughts and vision on this podcast. Any parting thoughts to wrap up? 

Inderpal: I read a quote recently that stayed with me: “AI won’t replace clinicians, but clinicians who use AI will outperform those who don’t.” I think it’s for everyone. Real transformation isn’t about tools; it’s how we imagine using them, how care is delivered, and how patients experience interactions. An AI agent can’t do that alone—it requires humans: clinicians and operators. That quote stayed with me.

Q: That’s a fabulous quote. I’ll end by saying we have an exciting partnership with a startup to bring AI at scale to healthcare systems. You know what I mean. So yeah, very happy to, uh, collaborate with you in there on that as well later on. So thank you once again and have a great day and we’ll catch up soon.

Inderpal: Thank you. Thank you for the opportunity and thank you to your viewers.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

 Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Unlocking Healthcare’s Future: Ashis Barad’s Vision for Digital Transformation

Unlocking Healthcare’s Future: Ashis Barad’s Vision for Digital Transformation

Unlocking Healthcare's Future Ashis Barad's Vision for Digital Transformation

In an insightful episode of The Big Unlock podcast, Dr. Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), shared his profound perspectives on the ongoing digital transformation in healthcare. Hosted by Rohit Mahajan, Managing Partner and CEO, and Ritu M. Uberoty, Managing Partner of BigRio and Damo Consulting, the discussion delved into Ashis’s unique journey from a practicing paediatric gastroenterologist to a leading figure in health technology, offering critical insights into the challenges and opportunities ahead.

The “Work-Life Integration” Philosophy: Passion as Fuel

Early in the podcast, Ashis tackled the traditional concept of “work-life balance” with a refreshing perspective, advocating instead for “work-life integration”. Drawing inspiration from books like “Conscious Business,” he suggests that when work is driven by passion, the lines between personal and professional life naturally blur. For Ashis, his work is a source of energy and passion, much like eating is an intrinsic part of life, not a separate task to be balanced. This deep personal investment, he believes, is evident in his fervent discussions about digital health, demonstrating how he truly enjoys the space. This approach underscores that true fulfilment comes from aligning one’s work with their core passions, allowing for a more harmonious and energetic existence, rather than a constant struggle for an elusive balance.

The Physician-Technologist Hybrid: Bridging the Gap

Ashis’s journey from a paediatric gastroenterologist who never stopped practicing to a Chief Digital Technology Officer is a defining aspect of his approach. He emphatically states, “I’m absolutely a doctor first, a technologist second, and I am to this day.” This unique dual perspective is a key differentiator that he believes brings immense value to discussions and solutions in healthcare technology. He intimately understands the frustrations faced by frontline clinicians when “logical” technology solutions, conceived by the C-suite, inadvertently add burden to their workflows. His commitment to spending time with clinical teams, observing their daily realities, and truly understanding their problems from the ground up ensures that the technology solutions implemented are not just theoretically sound but actually solve real problems without creating new friction. This commitment to bridging the gap between clinical practice and technological innovation is crucial for effective digital transformation.

The Driving Force: Democratizing Access to Right Care

A deeply personal experience from Ashis’s childhood fundamentally shaped his mission to democratise healthcare access. At eight years old, during a family trip to rural India, he contracted typhoid fever, which was initially misdiagnosed as malaria. Severely ill and rapidly losing weight, his life was saved by a physician cousin who correctly identified and treated his condition. This profound experience of receiving the “wrong care” until he gained access to the “right care” ignited his passion. He questioned, “How do we give, how do we distribute? How do we democratize? How do we get the right care to all people?” This foundational belief continues to fuel his digital transformation efforts, aiming to leverage technology not just for efficiency but to ensure equitable access and better health outcomes for everyone.

Agentic AI: The Workflow Orchestrator of the Future

Ashis suggests that the two most critical discussions in healthcare today are “agentic AI and change management”. He is a self-proclaimed “techno optimist” but also a pragmatist, wanting technology that genuinely works and solves problems. His excitement for Agentic AI stems from its potential as a “workflow orchestrator,” a capability largely missing in current point solutions or even the Electronic Medical Record (EMR) which, despite its utility, can be burdened by “friction and lots of clicks”. Healthcare, he argues, operates in complex workflows, not isolated moments. He states – “Healthcare is about workflows. Healthcare isn’t about a moment in time.” He further notes, “The only two things that we should be talking about in healthcare right now is Agentic AI and change management.

Every “handoff” in a patient’s journey – from finding care, to scheduling, receiving treatment, and post-care – presents opportunities for friction and significant waste due to a lack of coordination across vertically structured hospital systems. Agentic AI, by orchestrating across these traditionally siloed operations, promises to improve patient experience, enhance coordination, improve outcomes, and ultimately reduce costs by eliminating the “white space” between different care episodes.

HSS’s “Focus Factory” Advantage: A Lighthouse for Innovation

Ashis chose to join the Hospital for Special Surgery (HSS) for a very purposeful reason, despite having worked for much larger organisations. He refers to HSS as a “focus factory,” dedicated exclusively to musculoskeletal care. This specialisation, while seemingly narrow, actually impacts a significant portion of the population (30-40% experience mobility problems) and involves many algorithmic and elective procedures, making it an ideal environment for the application of Agentic AI. Unlike larger, more diverse healthcare systems where orchestrating across multiple complex specialties (e.g., cardiac, cancer) would take “5 to 10, 20 years,” HSS’s singular focus allows for deep vertical development and a much shorter timeline of “two to five years” for implementing comprehensive digital transformation. Ashis envisions HSS becoming a “lighthouse” for healthcare, demonstrating the feasibility of automating backend processes and orchestrating care workflows. The ambition is not only to show what’s possible but also to codify HSS’s world-class knowledge and distribute it globally, democratising access to the best musculoskeletal care.

Rehumanizing Healthcare with AI: Beyond Efficiency to Effectiveness

A crucial aspect of Ashis’s vision is that digital transformation, particularly through AI, should not lead to “less humans” in healthcare. Instead, he believes it will allow healthcare professionals to “double down” on direct human interaction with patients, freeing them from burdensome backend processes that can be automated by AI and agents. This fundamental shift asks the “existential question: what needs to be human, what is best done by human, what is best done by automation?” 

Furthermore, Ashis stresses that AI’s potential extends beyond mere efficiency, which he acknowledges healthcare desperately needs. The second, often overlooked, ‘E’ in AI is effectiveness. He says – There’s two E’s in AI and everybody forgets the second E. The first E is efficiency and everybody talks about efficiency. However, I think we miss the ball if we only focus on that one. And the second is effectiveness.

He argues that healthcare must do better than it does today, addressing unmet needs, improving access, and ensuring people receive the “right care” more consistently. HSS’s commitment is not just to perform optimally but to codify that optimal approach and leverage technology to make healthcare more effective at delivering superior musculoskeletal care globally.

Movement: The Heart of Longevity and Healthcare

Finally, Ashis expands HSS’s broader vision beyond orthopaedics to movement itself, a cornerstone of quality of life. In a world focused on wearables and longevity, the ability to move freely is paramount. While much of healthcare focuses on loss associated with disease, musculoskeletal care represents gain—being able to play with grandchildren, run marathons, and live actively into old age. This vision aligns with Ashis’s hope for AI and digital transformation to “actually rehumanize healthcare” by preserving and enhancing the human capacity for life and movement.

Ashis Barad’s insights paint a compelling picture of a future where digital transformation, guided by clinical understanding and a clear vision for effectiveness, improves healthcare delivery fundamentally. His practical approach, rooted in personal experience and strategic focus, offers a roadmap for leveraging advanced technologies like Agentic AI to streamline operations, rehumanize patient experience, and democratize access to world-class care—impacting both the industry and lives worldwide.

AI If Done Right Can Rehumanize Healthcare

Season 6: Episode #175

Podcast with Dr. Ashis Barad, Chief Digital Technology Officer, Hospital for Special Surgery (HSS)

AI If Done Right Can Rehumanize Healthcare

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In this episode, Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), discusses his journey in rehumanizing healthcare through digital health transformation. A practicing pediatric gastroenterologist, Ashis advocates for tech that genuinely solves problems, viewing himself as a “doctor first, technologist second.”

Ashis stresses on Agentic AI and change management as pivotal elements in healthcare transformation. Healthcare is inherently workflow-centric, not a series of isolated moments. Barad explains Agentic AI as a workflow orchestrator designed to reduce administrative waste, enhance patient experience, and accelerate the adoption of best practices.

Ashis outlines HSS’s strategy to leverage its specialized focus to build a modern data lakehouse architecture and deploy AI-powered solutions through key partnerships. He envisions rehumanizing healthcare by automating backend processes, expanding clinician-patient time, and codifying best practices that can be scaled globally, especially in musculoskeletal care and movement. Take a listen.

Video Podcast and Extracts

About Our Guest

Dr. Ashis Barad is a nationally recognized physician-executive and digital health innovator, currently serving as the Chief Digital & Technology Officer at the Hospital for Special Surgery (HSS) in New York, the world’s leading institution for musculoskeletal health. In this role, Dr. Barad leads enterprise-wide technology initiatives and digital operations collaborating with HSS leaders to enhance care delivery, the patient experience and clinical outcomes.

A board-certified pediatric gastroenterologist, Dr. Barad brings over 18 years of clinical experience and has been instrumental in driving digital transformation and modernizing healthcare delivery. Prior to HSS, he served as Chief Information & Digital Officer at Allegheny Health Network (AHN), where he led digital transformation efforts including enterprise EHR optimization, remote patient monitoring, AI integration, and patient-facing technology. He also held digital leadership roles at Baylor Scott & White Health, where he helped design and expand virtual care programs, including early telehealth initiatives, remote monitoring, and digital health platforms that enhanced access to care during the COVID-19 pandemic.

Dr. Ashis Barad earned his medical degree from Texas Tech University Health Sciences Center, completed a residency in pediatrics at Dell Medical School, University of Texas at Austin, and a fellowship in pediatric gastroenterology at Northwestern University.


Rohit: Hi Ashis. It’s great to have you back on the Big Unlock podcast. Thank you for joining us, 

Ashis: Rohit, Ritu, it’s wonderful being back. It’s been a few years and I’m excited to join again. Thank you for having me.

Rohit: Thank you, Ashis. As we discussed before the podcast, we are carrying on Paddy’s legacy and are very fortunate to be doing so. Our podcast is now more than 170 episodes, so we have a very excited base of listeners for this interaction with you. I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting, based in Boston and host of the Big Unlock podcast.

Ritu: Hi Ashish, really nice to have you on the podcast. Welcome. My name is Ritu Roy, Managing Partner at Big Rio and Damo Consulting, currently based out of Gurugram, India. Looking forward to a very engaging discussion. Thank you for being here. 

Ashis: So good to be here. Thank you again for having me. I am the Chief Digital Technology Officer at the Hospital for Special Surgery, which is a hospital on the Upper East Side of New York and the tri-state region on the East coast. We specifically focus on musculoskeletal care. You may know us as the orthopedic surgical hospital, but we actually have the largest rheumatology practice in the world, as well as psychiatry and other aspects of skeletal care, so we provide the full spectrum.

I started my career in Texas and I am a pediatric gastroenterologist. I’ve never stopped practicing and I practiced for a long time at Baylor Scott and White, which was the position I held when I was fortunate enough to meet Paddy long ago, where he became what I consider a friend.

I told him long ago, the Big Unlock was absolutely the main podcast I listened to—one of the first I started listening to when I wanted to learn about digital health. I was a frontline doctor and felt that digital health was going to be something significant for healthcare. Before people really knew, I think Paddy was onto something, and the fact that he made it his mission to talk about it, to educate, and to really move the field, is inspiring still. I think that has really created this forum of where it is now.

When I was at Baylor, I was fortunate to be at a system that was very far ahead in the virtual and digital space. I then moved over to Highmark and Allegheny Health Network as the Chief Digital Information Officer. I did that for a few years—a fantastic time. I learned about a whole new world as a doctor: insurance and value-based care specifically, and was able to make a lot of great programs there and do a lot of good work.

Then, when HSS came calling—which we can talk about more in the podcast as to why I made the move—I jumped at it about 10 months ago, and it’s been the best decision of my career.

Rohit: That’s great to know. Ashis, so very curious. You said that you never stopped practicing, right? You are looking at digital transformation initiatives at one of the largest hospitals in orthopedics and MSK in the New York area, which is one of the largest states. So how do you balance it, Ashish? That is one of my questions. And second, what motivated you in the first place? I know that you started your work as a physician, but what motivated you to become a physician? Please share that story with us as well.

Ashis: Oh gosh. Okay, so I have trouble with brevity at times, so I’m going to do my best. It’s a big question. Let me start with the latter and then you can remind me the former. As far as being a physician—and you said balance—I don’t believe in balance anymore.

One of my favorite books is Conscious Business. One quick premise of the book is that work-life balance is kind of like eat-life balance. You eat as part of life and you don’t really think of it as separate. Sometimes you have to stop to eat, sometimes you really enjoy the meal, and that meal can be at 11 o’clock in the morning, or it could be at nine o’clock at night, or anything in between. The point is, if your passion is your work, then there doesn’t have to be a line between the two. There are times in the day when I can take my son to a game at 3:00 PM and that’s okay, but then I may be working at nine o’clock at night, and that’s okay too. The balance aspect of things is always a struggle, but I think that if you strive for balance, you’re maybe focusing on the wrong thing because you probably don’t have balance with what you’re doing at work. Does it feed you? Does it give you passion? Does it give you energy? I don’t have a problem with it. My wife may argue at that point, but I don’t have a problem with it in the sense that my work is my passion. It’s what gives me energy, it feeds me, and I enjoy it.

I think before the podcast, you told me that when you met me the first time, you didn’t get too many words in because I was speaking with such passion and energy and fervor about what we were doing. That’s just me. I apologize for that, but that goes to show how much I really enjoy the space. My life is my work, meaning my kids, my wife, the dog, and everything else comes with it—just as passionate, just as energetic—and they melt together.

All of that being said, I’m a doctor first. I’m absolutely a doctor first, a technologist second, and I am to this day. I think that’s a differentiator. I think it’s a bit different than most people with my titles and roles, and I hope that brings a different perspective and value to the equation and discussions. I grew up during the High Tech Act and turned on a lot of Epic systems and what have you.

To answer your question directly about why I became a doctor: I am the first doctor in my family. So that’s not a typical Indian answer—many doctors and engineers in Indian families—but my parents immigrated right before I was born. I was born in Chicago, we moved to Texas when I was little. I’m an ABCD kind, if anybody knows that term. I was born in the States and grew up in Houston, and it was a passion from the get-go. I always knew I was going to be a pediatrician. I really enjoy families; I enjoy working with kids. That was something I just gravitated to, and there was never a question of anything else—pediatrics was something I wanted.

The other side of it is, we took a family trip to India when I was a kid, around eight years old. I actually contracted typhoid fever when I was in India—salmonella typhi. It’s very significant, and I was in rural India at the time. It was misdiagnosed as malaria and I was being mistreated. As an eight-year-old skinny Indian kid that maybe weighed 60 or 70 pounds at best, I lost 25 pounds at that time, and I was actually very close to passing. By luck, my cousin was marrying a physician in India—Manish, who lives in Ohio now. So, Manish, if you’re listening, you saved my life. Manish knows this. At every wedding we see, he says, “You’re alive.” To this day. Manish Bai came by because he heard that I was ill and he quickly figured out that I had typhoid fever. He brought me to his home, treated me, and I was able to get the right treatment and get back to the States. Obviously, I’m here and well.

That played a significant role in my life; I wanted to be a doctor like Manish—he is a family practice doctor in Ohio now. Pediatrics was something that resonated with me because I was a kid at the time. It plays a big role in who I am today. I received the wrong care, I didn’t have access to care—I received the wrong care until I got the right care. So the questions are: how do we distribute, how do we democratize, how do we get the right care to all people? Again, being at that age, I think it was a profound effect on me.

Rohit: That’s an amazing journey, Ashish. Thank you for sharing that background and insight. And Ashish, that brings us right to the persistent challenges in healthcare. We all kind of know what they are. I have a laundry list here: limited access, rising cost, clinician burnout, admin burden, and systemic waste. There are many persistent problems that we are trying to solve. I think we are making great progress on several fronts. How do you think about your digital transformation efforts at the current organization and what you have done before? Can you share with us some thoughts and ideas on how you approach this and what solutions you’ve been able to put into place to address these?

Ritu: Yeah, just before you answer, at Human X, there was a panel and a very interesting perspective on this—how slow things are in medicine, and how it takes years for doctors to adopt new ideas. Even the stethoscope took many years before it became acceptable. Because you bridge that gap between being a doctor coming into technology—when you address these problems, do you feel you have to address the issue between how technology moves, especially now with AI moving at light speed, and how things in healthcare move slowly? Is that frustrating for you? I just wanted to bring that in.

Ashis: Now you know that they have long-form podcasts that go on for 48 hours. There’s so much there. But knowing this is not one of those, let’s keep it succinct but try to create value in my answer.

A short answer—frustration—or it’s one of those things: how do you look at it, and do you see it as an opportunity? Do you see it as something we can really go do? The short answer is the time—even best practices. The amount of literature is doubling at a rate that is unreal. As a pediatric gastroenterologist, I can’t read enough journal articles to know what is published, let alone keep up with MSK, orthopedics, and everything else. There just aren’t enough human hours in the day, with all the other burdens of healthcare. There’s much more data and information constantly coming up. The average time for a physician to put a journal article or best practice into practice is something like 16–17 years.

Then, the innovation timeline—from something being invented to being used at HSS—is very long. The first knee implant was invented at HSS; it’s a culture of innovation. But by the time things get invented and then widely used, that timeline is massively long. How do we shorten that? I believe AI can significantly shorten that journey, especially with cognitive knowledge—getting best practices to pop up in the care journey, nudging clinicians when new evidence emerges. That is 100% doable, and you’re already seeing some vendors partnering to bring that insight into the workflow. That excites me.

For the broader question of digital transformation, there are many ways to frame it. The very broad way: how do we improve clinical outcomes and reduce administrative waste? Generally, let me zoom out and say—I was talking to an academic professor recently, and she said, “The only two things we should be talking about in healthcare right now are Agentic AI and change management.” To some degree, you can debate that, but they impact all aspects of healthcare.

I’m a techno-optimist, but I don’t just want tech for the sake of tech. I want tech that works, that actually solves problems. When I was a frontline doc, there was so much tech thrown at me, supposedly logical and great, but people didn’t realize it added burden to my workflow. So, part of my journey is representing the front lines—knowing what problems actually need to be solved. That takes a lot of listening, learning, and observation.

What excites me most now is Agentic AI. Healthcare is about workflows—it’s not about a moment in time. No doctor, nurse, patient, or consumer spends their healthcare journey in just a moment. Point solutions and things like generative AI chatbots still solve only moments in time. If I have a rev cycle authorization tool, or an ambient scribe, or an OR dashboard, that’s only solving a moment. But in healthcare, problems have downstream and upstream effects through workflows.

When I think about Agentic, it’s a workflow orchestrator—something that hasn’t existed outside the EMR. Of course, EMRs have workflows, but with lots of friction and clicks. Agentic has the potential to be a workstream orchestrator for everyone—consumers, operators, clinicians, administrators. This orchestration is where the magic and value will be, because every handoff in healthcare—from scheduling to aftercare—is where friction and waste happen due to lack of coordination across silos.

I believe as we solve across, and make the “white space” between verticals go away, we improve experience, coordination, and outcomes—and reduce cost. But that world has to be purposely built—it won’t magically appear from a platform or from thousands of point solutions that somehow orchestrate together.

My teams are working on that, with the first part being our data. We are building Lakehouse architecture—making sure our source of truth is in one place, linking all the data within context. Whether it’s consumer data, finance, operational, HR, clinical, wearable data, etc.—with all that linked, an agent system on top can orchestrate to take real action, which can then inform humans.

Lastly, it’s important I say all this is not to imply that there will be fewer humans in healthcare. If you’re touching a human, if you’re in front of a patient, we need to double down on that. We shouldn’t orchestrate, automate, or agent that away. Rather, we want to take away backend processes so we can double down on human engagement at the front end. The question is: what should be done by humans, and what by AI? Change management—upskilling, reskilling, onboarding—really means asking what needs to be human and what is best done by automation. That shouldn’t create fear that there’s loss; I think there’s actually gain—more time with patients, more humanized healthcare. I genuinely believe, if done right, AI has the potential to actually rehumanize healthcare.

Rohit: That’s true. 

Ritu: Great answer. Ashish really hit the nail on the head there. 

Rohit: I think it’s a different way of thinking, like you said, Ashish, about workflows, change management, Agentic AI, and all the white space that can be filled in. Would you think of any possible example? This data preparation that you’re building in the lakehouse is not a trivial effort. It’s going to be, possibly, a multi-year journey. And now you’re layering agent AI on top of it to fill this white space and orchestrate everything in the workflow. So is this too far in the future or near, and what are you seeing in terms of timelines? Also, in change management, what are some of the challenges you’re looking at, and how are you possibly overcoming those?

Ashis: It’s a great question and I understand the essence of it. This comes back to why I am at Hospital for Special Surgery. Let me frame that first, because I think it’s important. I was at much bigger companies, in terms of revenue and size. There’s a very purposeful reason for my move, based on my learnings. One of the struggles—and it’s understandable, especially since I’m very mission-based (as you may recall, I once said we’re missionaries, not mercenaries, and I still hold true to that)—is that healthcare is so complex. We all know that. Healthcare is complex due to the human factor, payment complexity, and more. In big systems, what’s harder is orchestrating between cardiac, cancer, peds, and different geographies and cities. What you described could take five, ten, even twenty years—it’s like boiling the ocean; it’s massively complex. You end up being one inch deep on everything and don’t know where to start. If I go to another system, do I start in cardiac, cancer, or orthopedics? No one wants to be second or eighth on the list; there’s politics and competition among divisions, with everyone wanting priority.

Healthcare is now hyperspecialized—doctors think inside their narrow specialty, which sometimes holds us back from thinking more broadly. The “focus factory” that is HSS—just doing one thing and doing it at a superb, world-class level—is very important. It lets us go deep, which is extremely difficult for broad systems. Even though orthopedic and musculoskeletal care isn’t super narrow (30–40% of people have mobility problems, so the impact is great), we get to go deep in one specialty. A lot of what we do is elective and algorithmic, which aligns well with Agentic AI.

So for us, there’s a bit of a perfect storm of positive aspects: we are the best at what we do, focusing on one thing, and it’s highly algorithmic (while still having plenty of human factors). I believe what I’ve described has a timeline of two to five years, rather than ten to twenty. At HSS, my and my team’s hope and vision is to create a very talented team to do this. We’re building a lighthouse for what is possible in healthcare, to show the world it’s possible to automate backend processes and orchestrate workflows. Our mission is to show that this role is possible—because of this focus factory aspect and being the best at what we do—and then distribute that globally.

If we codify the knowledge base that’s here at HSS, the best at what we do, why can’t AgTech orchestration distribute that, not only across rural America and the US, but also the globe? It can be codified. We really see ourselves as having an obligation to take what’s incredibly special at HSS and extend it. When you walk into HSS, you feel the experience, passion, and outcomes—it’s incredible. The question is, why is it only those living in the tri-state region who get access to what healthcare should be?

It’s really incredible. How do we take what’s so special, these care pathways, and this innovation, and broaden that knowledge, education, and capability globally? If we’re at the tip of the spear—using AI navigation, robotics, and other aspects of musculoskeletal care—then we want to broaden that knowledge and ability for everyone. 

And you know it, and the surgeons and the rheumatologists and the nurses at every level, an exceptional and it’s, you know, for me. It’s, why is it only if you live in the tri-state region, do you get access to the, what healthcare should be? 

And you know it—the surgeons, the rheumatologists, and the nurses at every level, they’re exceptional. For me, it’s: why is it only if you live in the tri-state region that you get access to what healthcare should be?

It’s really incredible. How do we take what’s so special? How do we take these care pathways? How do we create this innovation?

If we have something we’re able to use at HSS—and we are at the tip of the spear, using AI navigation, robotics, and other aspects of musculoskeletal care—how do we broaden that knowledge, education, and ability across the globe?

Rohit: That’s amazing, Ashish, very admirable vision. For those people on the podcast and for myself, I’m curious to learn a little deeper—it’s a more tactical than strategic question at this time, but you mentioned algorithmic. Could you throw some light on what you mean by that?

Ashis: Let’s talk to that quickly because I don’t want this to sound like just medical futurism—like, “oh, in 30 years we’ll do it.” How do we get there? As I said, data architecture is super critical, and one thing I’ve learned, and for which I’ve hired significant talent, is really focusing on the data. From my position, growing up as a doctor first, then becoming a technologist, everyone talks about the wonderful things, but what’s step one? Where do I put my first foot down? It’s very difficult. What I implore anyone on the podcast: really start with the data and make sure you have a data strategy that allows you to put an agentic system on top of it. The capabilities are there, the tools are there, but the context may not be. You have capabilities like OpenAI—now they’ve launched ChatGPT agents, it’s incredible. That’s the capability, but it has no context, no data to inform or make an intelligent decision. We need to get the context right, which is getting the data right. First step is making sure we get the context and the data right, and we’re centralizing that.

The second aspect is that we’ve made key partnership decisions. This is not something we’re going to do alone. We’ve made some key partnership decisions to bring big tech and startup innovation into our ecosystem. I’m a big ecosystem fan. I think it’s going to take an ecosystem. So, this week and others, we’ve launched ambient listening—it’s not just listening. We don’t see it as only ambient listening. Describing is only the first step. Having the scribing inform coding, CDI, authorizations, scheduling, even CRM tools—this is how we see the platform going forward. We’re looking at that.

Secondly, we’ve partnered with Palantir. What is Palantir doing for us? Palantir is thinking through the journey from end-to-end, from a consumer lens, from the beginning of care to orchestration. From operational flow, from a business intelligence standpoint—though that term minimizes it because it’s much more than that. It’s creating a kind of GPS—I want to define the main road of care, and when you get off the path, the GPS system activates to get you back on the main road. I think of Palantir building that with us.

Third, I’m a strong believer in low-code, no-code for the masses. Palantir is pro-code; it’s heavy and not something I can just democratize for any employee. So I need another agent layer of low-code, no-code. I think the future of work in healthcare is operator and engineer, unlike when I was a pediatrician and had a great idea but had to put a ticket into central IT, then wait six months only to be told it’s lower priority. I knew it would help my patients and outcomes, but I didn’t have the tools to build it in a safe, secure, PHI/HIPAA-compliant, easy workflow.

I think that’s changing. If I have an agent platform, from a coding perspective, I can say, “Here’s what I want,” and that’s what’s changed. OpenAI gives coding ability to everyone—it’s in plain English, written or verbal. So now, why can’t my revenue cycle folks build their own workflows? Why can’t my surgeons? That’s real capability. Why doesn’t it work today? Because the data is siloed. If they build an agent for calling post-op patients, another for collecting prompts, another for getting access, that’s like five different phone numbers—they’re not orchestrating. It goes back to vertical agents that aren’t orchestrating care, creating more friction and cost.

So, the answer is orchestration—having one agent platform for the enterprise and making sure the data is structured so it allows orchestration of those agents. So, it’s ambient, our Palantir work for high-code, and then an enterprise orchestration platform as well. Those are the three partnerships we’re building.

Rohit: That’s great. So Ashish, I think we’re coming towards the end of the podcast. As you said, there is so much to talk about—it went by so quickly and was a very different perspective. Would you like to offer any parting thoughts? Hopefully we’ll have you back soon to build on what we discussed.

Ashis: It’s important to me that we have a responsibility to transform healthcare and make it better. While I think about AI and agents—Dr. Michael O’Hara, our chief data analytics officer, always says there are two E’s in AI and everyone forgets the second. The first E is efficiency—everyone talks about that. We need more efficiency in healthcare, but I think we miss the ball if we only focus on one E. The second E is effectiveness. We can do better than we do today. It’s not just about doing things efficiently; the goal is to actually do better. People have unmet needs, lack access, or get the wrong care more than the right care. We need to do better—not just efficiently, but more effectively.

Hospital for Special Surgery does the best at what they do, and that’s true. What we’d love to do is ask: what do we do better, how do we codify and share that, and help make healthcare more effective in musculoskeletal care? If we can package up what’s special at HSS and make it a global brand, we should do that. Lastly, even though “surgery” is in our name, we actually do more non-surgical than surgical care at HSS—not many people know that. We live in the world of movement, and people care a lot about movement—wearables, watches, step counts. When you lose movement, you lose much. A lot of healthcare is about loss—loss of function, cancer, chronic disease—but what excites me is that musculoskeletal care is about gain. People want to move better, play with grandkids at 80, run marathons at 60, live better and longer. The number one component of longevity is movement. You don’t want to be 120 years old and wheelchair-bound—you want to be active. So we’re thinking more broadly—movement, not just orthopedics. I’ll leave you with that. Thank you.

Rohit: That’s awesome. Thank you so much, Ashish. It was pleasure having you on the podcast. 

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Interoperability and AI Adoption are the Pillars of Healthcare

Season 6: Episode #174

Podcast with Michael Marchant, Director of Digital Applications, Sutter Health

Interoperability and AI Adoption are the Pillars of Healthcare

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In this episode, Michael Marchant, Director of Digital Applications at Sutter Health, shares his expert perspective on how interoperability and AI are reshaping the future of healthcare. He discusses the promise of TEFCA (Trusted Exchange Framework and Common Agreement) in expanding data exchange beyond treatment to support broader care coordination. He also highlights California’s Data Exchange Framework as a model for equitable and inclusive health information sharing across diverse communities.

The conversation explores the real-world applications of generative AI in clinical settings, from ambient documentation to AI-powered inbox agents that reduce administrative burden and help clinicians deliver faster, more personalized care.

Michael emphasizes the importance of assistive, not autonomous, AI, spotlighting use cases where technology enhances the capabilities of care teams without replacing the human touch. Drawing on decades of experience in health IT and data policy, Michael offers a grounded yet visionary take on building scalable, interoperable, and patient-centered digital ecosystems. Take a listen.

Video Podcast and Extracts

About Our Guest

Michael Marchant is a seasoned healthcare technology executive with 30+ years of leadership experience. His expertise lies in the strategic implementation and integration of enterprise systems and workflows across diverse healthcare environments. Michael has held pivotal roles with technology vendors, government contractors, and healthcare provider organizations, providing him with a well-rounded perspective on industry challenges and opportunities.

Passionate about advancing healthcare interoperability, Michael actively contributes to shaping the future of the industry through his leadership roles in various organizations. He serves as Chair of Epic’s Care Everywhere Governing Council, Board Member for eHealth Exchange and Co-Chair of the Carequality Advisory Committee. Additionally, previously served as Co-Chair of the AAMC's Diversity and Inclusion Workgroup, two-time member of the HIMSS Interoperability Committee, member of the SDoH workgroup and Blockchain Task Force as well as several HL7 FHIR Accelerator workgroups.

Currently, Michael is the Director of Digital Applications at Sutter Health, where he leads the Sutter Community Connect and Enterprise Data Integration teams, driving innovation and collaboration to enhance patient care and data sharing.


Q: Hi Michael. Welcome to the Big Unlock podcast. Very excited to have you here. The healthcare audience is super excited to listen to our podcast. I’m Rohit, the Managing Partner and CEO at BigRio and Damo Consulting. With that, I’d like to request you to introduce yourself, Michael. 

Michael: Yeah, I’m excited to be here too. I’m Michael Marchant, Director for Digital Applications at Sutter Health. I’ve been here almost a year now, focusing on core interoperability, enterprise data integration, and also running our Community Connect program with about 250 practices.

I’ve been in interoperability for a long time. I’ve participated on the Epic Care Everywhere Governing Council, I’m on the Carequality Advisory Council, and I serve on the eHealth Exchange Board. So, interoperability and health technology are core to what I do every day—making decisions and planning for how we get people the data they need to make decisions around their healthcare. Excited to be here.

Q: That’s great. Michael, would you like to share your journey in healthcare? What got you started? What roles have you played, and what do you find interesting about this field? 

Michael: It’s a long and interesting story. I went to college in Virginia at Old Dominion University, studying Human Resource Management. I started as an internal auditor. My father worked for a small software company called Comcare, and when I moved to California, they were looking for someone to install patient financial software—AP, GL, payroll, personnel.

I had some technical background but no real experience in software implementation. They were willing to train me, and I got on board. My first foray into interoperability was doing payroll installs—sending data from point A to point B to ensure employees got paid. That was my first critical experience with data exchange.

I moved from payroll into accounts payable and general ledger—again, lots of data movement and system frameworks. Comcare had a partnership with DataGate, which had an interface engine, and that’s where I started programming. That kicked off my career in health IT.

After having kids, Southern California became expensive, and my wife, despite her advanced degree, wanted to stay home with the kids. So, we moved to Sacramento, and I started with Sutter. I was part of the Y2K program with MedSeries4, working on integration across sites to ensure interfaces were Y2K-compliant—moving from two-digit to four-digit years and ensuring backward compatibility.

At Sutter, I moved up from analyst and project manager to director. Sutter Connect brought me over to run what we then called the Independent Practice Services program—it wasn’t yet Community Connect. We deployed GE’s product (GE had acquired IDX) to about 50 practices and 100 physicians before I moved on.

After that, I worked with the state contractor for the EHR Incentive Program. ACS Xerox partnered with California’s Department of Healthcare Services to build the state’s enrollment portal for incentive funds. I helped with training, enrollment, and deployment. By the end, we had paid out about $500 million in incentives.

Then I went to UC Davis, where I was Director of the Interop and Innovation Team. That’s when I got deeply involved in the industry—Carequality, HL7’s Interop Committee, and the blockchain task force. I still believe blockchain has potential, even if people aren’t quite comfortable with it yet.

I spent about 10 years at UC Davis and recently returned to Sutter, leading two teams. For me, technology is in the background, serving a purpose—automating, simplifying, accelerating. It’s about getting the right information to the right people so they can make the best decisions about care.

That’s what drives me: improving processes, delivering value to both internal and external stakeholders—our physicians, clinicians, and most importantly, the patients. This work creates better care, and I try to reinforce that with our teams. Even when you’re buried in the weeds of programming or writing specs, I try to help everyone see the forest through the trees.

Q: That’s awesome. And Michael, could you talk to us at a high level about Sutter as an organization—patients being served, locations, hospitals, physicians, and overall size? 

Michael: For sure. Sutter Health is a large organization in Northern California. The Sutter footprint goes from about Sacramento, or a little north and east of Sacramento, down to Santa Barbara. We recently acquired the Sansum Clinics in the Santa Barbara area. So, from north of Sacramento to Santa Barbara, you’ll find Sutter entities and coverage.

We have around 25 to 27 hospitals, a number of ambulatory surgery centers, and we’re continuing to grow in the ASC space. We’re building a couple of cancer centers and a few other joint ventures. We really serve the population of Northern California—probably 2 to 3 million covered lives from a value-based care perspective, and hundreds of thousands of visits. We have a strong online presence as well as a physical presence in many Northern California communities, always aiming to deliver the best care.

Sutter has won a lot of awards—I don’t have my slide deck in front of me, but if I were doing a PowerPoint, I’d have the slide with all the awards.

Q: This high-level information is awesome, thank you. It’s good to know—it’s a pretty large footprint. With that, I’d like to segue into the first question. We were talking earlier about the CMS and ONC RFI that’s out right now and the TEFCA implementations you’ve seen to date. How do you think about this emerging process? 

Michael: Yeah, I’ll start with TEFCA and then go to the RFI. The general idea from ONC, now under CMS, is to expand the capabilities of our national networks.

Historically, eHealth Exchange, CommonWell, and Carequality were the three national networks enabling organizations to do nationwide data exchange—mostly CCD documents—on a request-response basis, securing the connections and delivering data to the requesting organizations.

We’ve grown that network significantly. In a recent committee meeting, we learned that 1.1 billion documents were exchanged in April alone between participating organizations. The structure of those networks is treatment-based exchange—organizations treating patients and needing information to assess and understand the patient’s history to provide the best real-time care.

But we kind of stalled there. We were stuck at treatment-only. Many organizations that needed access to information couldn’t participate. During COVID, public health access became paramount, and CMS allowed some exceptions under emergency orders, which enabled that information exchange. But for broader, public health, and operational exchanges—such as care gap closures in value-based populations—those aren’t widely supported on treatment-based networks.

TEFCA’s promise is to expand this. Many healthcare ecosystem organizations—long-term care, SNFs, nursing homes, and community providers—weren’t eligible under the EHR Incentive Program and thus aren’t participants in the current networks. Roughly 30% of healthcare data holders aren’t participating in current treatment-based exchanges. TEFCA aims to bring them in and broaden the scope of who can participate.

It’s not just about treatment. The next phases involve operational exchange, payment exchange, public health, and research. The idea is to build a network that supports all of these use cases and welcomes organizations that couldn’t participate before—either because they’re not involved in treatment or they’re not HIPAA-covered entities.

CMS is taking the lead. There are now 8 to 10 QHINs (Qualified Health Information Networks). Most EHR vendors, Surescripts, eHealth Exchange, KONZA, and others are participating. The RFI seeks broad input on how to support this ecosystem: improving provider adoption and usability of digital tools, strengthening data exchange, ensuring access to comprehensive patient data, and advancing value-based care through technology.

It’s about identifying data needs, reducing administrative burdens, enabling patient and caregiver access to digital tools, managing identity, ensuring equity in digital health access, and setting future-proof certification criteria for participation.

I encourage everyone to comment and provide feedback to CMS based on their experiences—so these standards and frameworks are implemented correctly. That participation is vital.

Q: That’s awesome to know. Now, moving forward, Michael—on digital health tools, AI, and of course now GenAI and all the new LLMs coming into play.
Could you talk with us about the risk profiles and risk appetite for health systems, and share some examples you’ve seen at Sutter or at UC Davis? 

Michael: Yeah, for sure. AI is used for a large number of things—NLP, machine learning, RPA—those have been in place for a while, and we’ve been leveraging them. Now we’ve wrapped them under the umbrella of AI, but the buzz right now is around GenAI, especially ambient voice.

The idea is a physician in the room with a patient, having a conversation while an ambient agent listens in the background. It generates a note at the end of the encounter, allowing the physician to focus on the patient, not the computer. It makes the interaction more personal. The agent formats the note with relevant information while excluding casual conversation.

This technology has helped physicians get off the keyboard and return to practicing medicine. Satisfaction scores are high. It’s reduced pajama time—charting after hours—for those using it. We’re working to expand adoption across the board.

We’ve seen similar value in Epic. There’s an inbox agent that can read patient messages, prioritize them, and even draft responses. A physician managing a thousand patients receives a lot of messages. The AI agent helps flag urgent ones and draft thoughtful replies. In some cases, the AI-written replies are more empathetic than the rushed responses doctors might send. It’s all reviewed and approved by the physician, of course, but the assistive value is significant.

In radiology, AI helps prioritize breast imaging. It flags anything abnormal and puts it at the top of the radiologist’s worklist instead of first-in, first-out. That ensures patients with serious concerns are seen sooner. Given the shortage of radiologists, this makes a big difference.

We also implemented a tool for diabetic retinopathy screening. It takes images of the eye and scores them. An untrained person can operate the device, which helps us scale the service. Previously, there was a long wait for tests—now we can screen thousands of patients and prioritize those needing care.

So across the board, these tools are assistive. They don’t replace clinicians but help deliver faster, more targeted care.

Q: That’s great to know. So do you think, Michael, that at any point, any of this AI — in the examples you might be working on or seeing — is going to be autonomous? 

Michael: I think there are probably some places where autonomous activity can occur in low risk — and that’s where you move to back office, right? A lot of the patient-facing care applications are going to be assistive or augmented rather than delivering the final result.

Things in the administrative area — like claims and claims status — a lot of that is logging into portals, sending messages, or even sending a fax. Those can be automated. Responses can be automated. You can OCR faxes and apply some RPA or ML rules to those transactions and execute commands. It happens in a repeatable, machine-like way.

But when you’re talking about a patient having a procedure or getting a test or result, the AI can help look at larger datasets. Say you have a patient with a specific condition. You can use an LLM to say, “I have Rohit, who has this condition. What are the outcomes for others with similar conditions? What medications did they take?” You help frame a care plan based on data from 100,000 patients instead of anecdotal information or outdated knowledge. So you’ll see more research-integrated LLM data that allows physicians to target patients with similar profiles — but it’ll still be assistive and suggestive, not making final decisions.

Q: That’s a good way to think of it. The key thing here is the risk factor. Lowest risk things you might automate; high risk, you lean towards assistance. 

Michael: Yeah, I’ll give you an easy example here. I’m in IT, so I’m participating in a pilot with a blood pressure device.

What happens is I take my blood pressure, and the reading goes to Epic. Part of the AI in the background looks at the readings, and if mine is not what it should be, it sends me a text saying, “Hey, your reading was out of band. You might want to take a sip of water, relax for a second, and retake your blood pressure in 15 minutes.”

All of that is low risk and automated. Nobody has to review the score. It knows it’s out of band, and it recognizes there might be some environmental factors impacting the reading. So it automatically sends me a suggestion: “Hey, your blood pressure was high. Could you take another reading in 15 minutes after calming down or making sure nothing was off?”

That sort of automation is low risk. It reviews the data — so there’s some oversight — and it actually gives the patient comfort. It makes you think, “Oh wow, someone’s paying attention,” and that kind of outreach builds confidence. It’s a patient satisfier. It improves safety. There are a lot of benefits — and again, it’s low risk.

You know, I’ve done it in the office — taken a reading, it was a little high, and they’d say, “Okay, let’s take it again.” Two minutes later, it’s normal. So this is similar. And when you think about caring for a larger set of patients, we’re going to distribute that blood pressure cuff to thousands of people. We don’t need a ton of nurses looking at every result. We just need the rules in place: if something’s out of band, ask for another reading. If it’s out again, then alert a clinician.

Then, that physician or clinician might say, “Hey, you’ve had a couple high readings in a row. We may need to adjust your medication. We might need to bring you in. Or, this looks serious — please go to the ER.”

That’s where you apply the right resources in the right way. AI becomes a tool to help prioritize risk. For patients who are higher risk — and where there’s information you can act on quickly — a person can step in rather than relying solely on tech.

As we get more advanced, we’ll expand this kind of approach into other use cases beyond blood pressure to truly provide personalized medicine. Back when Bush talked about personalized medicine, it was tied to genetics and DNA. But I think personalized medicine is really about treating each patient as an individual and giving them feedback and support to manage their condition proactively — before there’s an adverse health event.

That’s what value-based care is about. We want to keep people out of the hospital and care for them before they get sick. These low-risk AI tools make a lot of sense for that. We just need to figure out a reimbursement and incentive model that encourages both patients and providers to adopt them — instead of waiting until people get sick and need hospital care, which, of course, is expensive for everyone.

Q: Of course. So Michael, moving on to another aspect of innovation—thinking about it in the framework of new announcements. Oracle has announced a completely new redesign of the EMR system, and we all know Epic is the big, heavily used system by health plans and health systems. How do you think about innovation in this scenario?

Michael: One of the things about Epic—and again, Epic is a significant vendor in the electronic health record space—they’re a market leader. They deliver great technology. I’ve been a customer of Epic since 1998, so I’m very familiar with them and their architecture.

I think one of the key aspects of modernizing electronic health records is abstracting the data, workflow, and technology. Epic, like most of the historical EHRs, was built first as a billing system, and then as a clinical documentation system. A lot of the workflows inside current EHRs, including Epic, are really tied to documenting the right things so that when we send the claim to the payer, it’s approved—not denied—because we’ve checked all the right boxes or coded it correctly.

Looking at Oracle’s new ambitions—they’re focused on an AI-native, cloud-native, redesigned user experience that really puts clinical workflow first. Instead of thinking about billing first, they’re thinking about the clinician experience first, and then reverse-engineering it to handle administrative tasks using AI and other tools.

Whether it’s Epic, Meditech, Cerner, Oracle, Allscripts, Greenway, Athena—you name it—the future is about enabling the right workflow for the right specialty and clinician. There should be personalization that allows them to work in a way that makes sense to them, while still giving access to all the necessary data.

If we can create data liquidity—which is what they’re aiming for with FHIR APIs and API-enablement on the back end—then we’re no longer chained to Epic or Oracle’s UI. If we can access the underlying data structures, we can build apps on top of that to create more fluid, user-based workflows.

We’ve gone through different UI development phases—widgets, phone apps, watch apps—and the future will be about building UIs that are intuitive for clinicians. They should meet clinical needs first, and then use AI and automation to handle the back end—like billing, compliance, and documentation. That way, we’re not robbing innovation on the front end just to serve billing on the back end.

You’ll prompt clinicians when needed—like, “Did you ask about smoking status?”—instead of forcing them to check endless boxes. Whether it’s Oracle or a smart startup, someone is going to leverage existing EHRs—like Epic’s infrastructure and data—but create a much better UI and clinical experience on top.

Replacing an EHR is incredibly expensive. So instead of ripping and replacing Epic, maybe you introduce a SMART-on-FHIR application for cardiology that works better than what Epic has. You get some market traction, then build apps for other specialties.

You’re not going best-of-breed across everything—just best-of-breed on UI—while still using your existing EHR’s infrastructure and data model to drive the new experience.

Q: That’s a great perspective on innovation, and I really like the term you used—data liquidity. It’s an awesome way to think about it. As we come toward the end of our podcast, Michael, I wanted to touch on one more topic—the California Data Exchange Framework, which you mentioned earlier. Tell us more about that and where you see it going.

Michael: Yeah, so California—like every state—thinks they’re unique. Governor Newsom signed the Data Exchange Framework legislation a couple of years ago. It’s essentially establishing a parallel data exchange within the state that allows a person living in California to access their longitudinal health record, including social services data and public health data.

They’ve created a TEFCA-like model with QHIOs—Qualified Health Information Organizations—that help facilitate participation. There are requirements around admit notifications, panel management, direct messaging, and data exchange for treatment and public health operations.

Right now, the Data Exchange Framework is a legal framework, but not a technology framework. They’re trying to be technology-agnostic and allow organizations to participate using whatever tools they currently have.

One challenge is the need for point-to-point connections. If I want to exchange data with, say, a housing agency or public health department in Sacramento, I have to figure that out directly with them. But the legal framework provides cover—a data use agreement that says the state has authorized the exchange, so we don’t need separate agreements.

Many groups involved—like housing or public health—haven’t historically participated in data exchange. So the questions are: What data can public health have? What can a housing agency or non-covered entity access? How do we ensure the right security profile? Who’s authorized to participate?

Today, to find out who’s signed the Data Exchange Framework, you have to visit a website and look them up on an Excel spreadsheet. That’s obviously not scalable. The future needs to include a real technical infrastructure to support this exchange—not just point-to-point connections, but a true network effect.

It’s similar to TEFCA but running in parallel. I’m working with BluePath Health, EMI Advisors, and others on this in California. I serve on the Technical Advisory Committee led by CDII to provide feedback and help define the standards and frameworks to enable this exchange.

It’s an exciting initiative. SB 660 is moving through committee and will help enforce participation—not just in signing agreements, but in actually exchanging data. That’ll give the framework some real teeth.

Of course, there are challenges—AB 352, for instance, which prevents abortion-related data from leaving the state. So there are lots of complexities. But California is serious about interoperability, governance, and regulation, and we’re all working to comply. Hopefully, this framework will help us get there.

Q: That’s awesome, Michael. So, any other parting thoughts for the listeners of the podcast from your side before we wrap up?

Michael: There’s a lot happening, and it can feel overwhelming. What I always tell people—like I tell my kids going off to college—is: get involved. Even if it’s something small, participate. Find people who are involved, ask questions, learn from them.

Many of the things I’ve learned came from conversations with really smart people. I participate in the Health Tech Talk Show with Lisa Bari and Kat McDavitt—they’re incredibly knowledgeable. Lisa was the former CEO at Civitas and now works at Innovaccer. Brendan Keeler also shares great content on LinkedIn and through his blog.

Join a committee. Help make sure your organization is ready. If you’re in the interoperability or health tech space and you’re not moving forward, you’re going to get left behind.

Engage, understand, and provide feedback—especially to things like RFIs. If you haven’t read them, plug them into your AI, get a summary, and start there. Use the tools we have.

And I always tell people: I’m an open book. If you have questions, feel free to connect with me on LinkedIn—we can have a great conversation. Thanks again for having me on the podcast, Rohit. Exciting times ahead for all of us.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

AI in Pharma Beyond R&D: Novo Nordisk’s Alicia Abella on Building a Scalable Innovation Model

AI in Pharma Beyond R&D: Novo Nordisk’s Alicia Abella on Building a Scalable Innovation Model

AI in Pharma Beyond R&D Novo Nordisk’s Alicia Abella on Building a Scalable Innovation Model

In a recent episode of The Big Unlock podcast, Alicia Abella, AI Product Lead at Novo Nordisk, joined host Rohit Mahajan to discuss how artificial intelligence is transforming the pharmaceutical industry, especially in the commercialization space. With a career spanning academic research, telecommunications, and big tech, Alicia’s perspective on AI is both technically grounded and strategically visionary. 

From pioneering research in natural language processing (NLP) at Columbia University to helping scale AI platforms at Google, Alicia’s journey offers a compelling narrative about AI’s evolution and its emerging potential in healthcare and pharma.

From Lab to Life Sciences: Alicia’s Full-Circle AI Journey

Alicia’s work in AI began during her PhD at Columbia University in the 1990s, where she built a system to analyze radiographs and automatically generate radiology reports—a precursor to many of today’s AI diagnostic tools. That work led her to AT&T Bell Labs, where she contributed to cutting-edge speech and natural language processing research.

After 25 years at Bell Labs, she transitioned to Google Cloud, where she helped lead global AI strategy and worked on products like Vertex AI and Gemini. Her move to Novo Nordisk was driven by a desire to apply AI in a more purpose-driven setting. “I think pharma is still relatively new to AI, especially in commercialization. A little bit of governance, without being too heavy-handed, can help drive innovation and guide it in the right way for the right problems.”

Unlocking AI Use Cases in Pharma Commercialization

While most pharma AI initiatives have focused on drug discovery and clinical trials, Alicia sees immense opportunity in commercial operations—where AI can streamline processes, accelerate marketing execution, and improve personalization. Some of the most impactful AI use cases at Novo Nordisk include:

Knowledge Search and Retrieval: With massive volumes of data coming from internal reports, market intelligence, and vendor insights, finding relevant information can be overwhelming. Alicia’s team is implementing generative AI solutions with conversational interfaces that make it easy for marketing and insights professionals to extract answers—with references and source links.

AI-Powered Content Creation: Novo Nordisk is also using GenAI to automate ad copy variations, create short video content, and support early-stage creative development—dramatically reducing time-to-market for campaigns.

HCP Segmentation and Outreach: Traditional AI models help the company analyze prescribing behaviors, patient demographics, and treatment patterns—enabling smarter engagement strategies with healthcare providers.

These are real, tangible applications that deliver business impact—and Alicia is keenly focused on productizing only what adds real value.

Driving Cultural Change: The AI Ambassador Program

One of the biggest challenges in deploying AI at scale is change management. Alicia’s approach to this challenge is refreshingly people-first. Early in her tenure, she launched a “listening tour” to engage leaders across the organization and assess the current state of AI awareness and readiness.

She discovered a broad spectrum of sentiment—ranging from excitement to fear—driven by varying levels of understanding and concern around compliance. To address this, she developed the AI Ambassador Program, a grassroots initiative designed to foster peer-led learning and adoption. “In order to drive adoption of any product, you have to make it usable. You have to make the experience something that people will want to use—something intuitive, easy to use, that will drive adoption.”

The program has already exceeded expectations in participation. Ambassadors meet monthly to explore AI use cases, learn about emerging tools, and collaborate on safe experimentation within legal and compliance frameworks. It’s a model that blends top-down strategic intent with bottom-up enthusiasm—and one that Alicia believes can be replicated across industries.

Bringing a Product Mindset to AI Development

Another key differentiator in Alicia’s strategy is her commitment to a product management mindset to guide AI development at Novo Nordisk. Drawing from her experience at Google and AT&T, she’s brought a structured lifecycle approach to AI solution development: design, develop, test, monitor, iterate. Too often, she says, technologists get enamored with the possibilities of AI and rush to build solutions without fully understanding the problem. Her team starts with a foundational question: Should we be building this at all? Alicia adds, “Just because you can build something doesn’t mean you should.”

She emphasizes the need to prioritize AI initiatives only after validating user needs, business value, compliance implications, and technical feasibility does a solution move forward. This governance-light but insight-heavy approach ensures that Novo Nordisk focuses on building AI products that deliver real impact—not just innovation theater.

Partnering with Compliance from Day One

In an industry governed by strict regulations, compliance cannot be an afterthought. Alicia’s approach is to involve legal and data ethics teams early—during ideation, not after development. By building these partnerships proactively, she avoids project delays, ensures alignment with ethical standards, and creates a culture of responsible innovation.

“I told them, ‘You’re going to be my BFFs,’” she said. “I bring them in even when we’re just thinking about an idea—before any development starts. That way, we avoid surprises and ensure we’re building in a compliant manner.”

This early-stage partnership helps place guardrails that manage risk without stifling innovation—a delicate balance that’s essential in highly regulated industries.

Future Trends: LLMs, UX, and Human-AI Symbiosis

When asked about the future of AI, Alicia points to two major areas: user experience and contextual intelligence. “I think a trend that we’re going to see going forward… one of these big tech giants that are now in the business of creating large language models will now have that focus on the user experience.”

Alicia believes the success of ChatGPT wasn’t just about the model’s power—but the simplicity of the interface. As pharma builds its own AI tools, UX must remain a top priority to ensure adoption. But usability alone isn’t enough. She also anticipates a new evolution in AI models and adds that, “It’ll be interesting for how we see these large language models evolving—so that they go beyond just maybe text, image, and video, and start to bring in more contextual knowledge.”

She imagines a future where AI systems can incorporate real-world context and nuance like human collaborators. And the human-AI relationship is something Alicia reflects on deeply and states, “I think we still have that desire to see how do we make these machines behave maybe more like humans—without taking us out of the loop.”

This human-in-the-loop model is especially important in healthcare and pharma, where empathy, nuance, and ethical judgment matter.

A Playbook for Responsible AI in Pharma

Alicia Abella’s work at Novo Nordisk offers an inspiring model for how pharma companies—and other regulated enterprises—can responsibly scale AI. Her leadership showcases the importance of:

  • A product-driven, outcome-focused strategy
  • Strong compliance and legal collaboration
  • Cultural change through education and empowerment
  • A relentless focus on usability and trust

As more pharma companies explore AI applications beyond R&D, Alicia’s playbook provides a real-world guide for building AI programs that are credible, compliant, and customer-centric.

Transforming Wellness-First Senior Communities Through AI and Social Determinants

Season 6: Episode #173

Podcast with Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer, United Church Homes

Transforming Wellness-First Senior Communities Through AI and Social Determinants

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In this episode, Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer at United Church Homes (UCH), shares how the organization is reshaping the future of senior living. Moving beyond a traditional housing-first model, UCH is leading a shift toward a wellness-first approach that prioritizes health, dignity, and independence for older adults.

With more than 100 communities across 15 states, the organization is leveraging scalable, data-driven strategies to support aging in place, particularly for vulnerable populations. Mike explains how understanding and addressing social determinants of health (SDOH) is key to improving outcomes, and how machine learning is helping evaluate the impact of non-clinical interventions in real-world settings.

From transitioning fall detection to fall prevention, to exploring lightweight sensor technologies, Mike emphasizes the importance of proactive care and personal motivation in sustaining long-term wellness. He also introduces the organization’s Entrepreneur-in-Residence (EIR) program—a unique initiative that brings innovators into senior communities to co-create human-centered solutions rooted in real-life experience. Take a listen.

Video Podcast and Extracts

About Our Guest

Mike is the Senior EVP, Chief Transformation and Innovation Officer at United Church Homes (UCH) – non-profit provider of housing and services that support the health and wellness of older adults no matter where they call home. In his role, Mike leads the development of new product and service offerings using Human Centered Design principles that take a ‘problem first’ approach to investigation. Mike also oversees all innovation pilots at UCH as well as the development of its online platforms.

Prior to joining UCH, Mike held executive leadership positions in the home care space and with AARP where he developed supportive programs for family caregivers and worked to integrate non-clinical supportive care into managed care programs.

As a passionate advocate for older Americans, Mike champions common sense, practical approaches to engagement – recognizing the harmful effects of ageism when it comes to self-management and one’s potential to age independently at home. He frequently champions the opportunity to measure the impacts of motivation, engagement, health literacy, community and spiritual wellness within patient-centered care models.

Mike holds a BA in Economics from McMaster University and an MBA from McGill University with ongoing executive education at the Harvard School of Management, MIT and IDEO.


Q: Hi Mike. Good to have you on the podcast today. Mike. I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting. I’m very fortunate to carry on The Big Unlock podcast, which is the legacy of Paddy Padmanabhan, who was the founder of Damo Consulting. We are, I think, getting well over 170 podcasts at this point. I’m super excited to have you here today.

Mike: Hey, Rohit, great to be on. Thanks for inviting me. I am currently the Chief Transformation and Innovation Officer at United Church Homes. We are a nonprofit provider of senior living, with over a hundred different properties in 15 states and on two tribal nations. That includes about 75 affordable housing properties—owned and managed.

And then in the state of Ohio, where we’re headquartered, we have 10 owned and managed skilled nursing communities. We have life plan communities, and we also have independent living communities focused on the middle market.

We’ve definitely been growing—a very innovative organization that I’m proud to be part of. That includes growth into more services. We’re starting to do programs with CMS, like the GUIDE program. We also have a joint venture with a managed care payer called CareSource.

I really think that’s the future for many senior living providers—growing from being just housing providers to becoming health and wellness providers, with housing at the core.

Q: That’s amazing. So Mike, would you like to share with us your journey in healthcare? What got you started, how did you get to where you are, and what are some of the things you’re seeing for the future? 

Mike: Well, thanks for asking the question. When I started my career, I came down to the U.S. from Canada right out of grad school. I got into advertising, and with my first degree in economics, I became very compelled by the age wave.

I think there’s nothing more predictive—outside of maybe climate change—of future demand than the current age wave. It’s what I call the anomaly of the baby boom generation. This huge baby boom spike—we’re sitting here on July 14, 2025, and in 2027, we’re going to have the most people turning 80 in any year ever. Why? Because of what happened in 1947.

We know people needing healthcare services today are just a small fraction of what we’ll see in the future. So why not get in and plan for it?

Being a very naive Canadian at the time, I thought, “Maybe I should just get into the healthcare space—because that’s easy in the U.S., right?” Very straightforward! But it’s been compelling.

I started at AARP. They were a client of mine when I worked in advertising, and they’re the largest association for older people in the country. Then I moved into health IT with a role at Surescripts, the nation’s e-prescribing network, and later returned to AARP. So I got a taste of interoperability, health tech, and how we could apply that to aging.

With labor shortages and so many constraints, I started asking: how can technology fill the gap and support people at scale?

Through further experience, I realized clinical care isn’t the most important factor in the health and wellness of older people. It’s the non-clinical care and functional support that matter more.

So I’ve built expertise in social determinants of health—risk modeling and strategies to support aging at home. And importantly, that doesn’t just mean care and safety. I think it’s far more effective to support someone’s needs when there’s real meaning behind it.

One of my favorite sayings is: “Nobody takes their pills because they like how they taste.”

I’m a big fan of more relational care models, where we work hand in hand with people—focusing on their personal goals and motivations. And I hope that at United Church Homes, and in the future, that’s the kind of model I can help advance.

Q: That’s an amazing journey, Mike. Given your deep immersion and expertise in this area, would you like to talk about some growth strategies for senior living care?

Mike: I’ve had the privilege of working with United Church Homes for almost four years, and it’s helped me really get to know the nonprofit senior living industry. I’ve been incredibly impressed. As I like to say—we do the most with the least.

Especially in affordable housing. For about 30 years, United Church Homes and others in our space have been participating in a program that HUD (Housing and Urban Development) started called Service Coordination in Multifamily Housing. They provide funding for staff to be at those properties and conduct social determinant assessments on residents.

We help reduce risks by connecting residents to local community resources they may not know about. We also help qualify people for Medicaid and Medicare waivers. More importantly, we talk people down off a cliff.

What I mean is, when someone is going through a health or aging challenge for the first or second time—we’ve been through it hundreds of times. So we can tell people what’s normal, what’s not, and what might happen next.

That program has been amazingly effective in keeping people out of the hospital and skilled nursing. We have about 3,800 people in affordable housing—3,200 of them are on service coordination contracts. In the last 15 months, only 50 transitioned into skilled nursing, and 110 had an unplanned hospitalization. These are very low numbers—and they’re similar to others in our space.

So when I think about growth in senior living, I think about unbundling this service skillset and offering it as a standalone solution. It’s a plug-in for managed care, employer programs, and long-term care insurance. I think the future of senior living is transitioning from housing providers to health and wellness providers—with housing at the core.

I also think the industry needs to shift from centralized service delivery to a more decentralized model—because there’s an opportunity to support people in housing who could never afford or don’t want to move into a community. A hub-and-spoke model—I think we’ll see more of that in senior living.

Q: That’s very interesting, Mike. Just curious—typically at what age do people come into these kinds of facilities? What have you seen, and is that changing? 

Mike: Yeah, I mean, average age is going up—we’re getting them older and sicker. The lifetime value is going down. So the business strategy has to diversify toward more community-based models—serving people where they are.

The average time between knowing you need to move into a community and actually doing it can be 9 to 18 months. What happens in between? That’s where we need technology to help. Technology that tells us when someone may need assistance—and also helps capture that data.

Q: Right, of course. And you talked about social determinants of health—that caught my attention. How does that play into your transformation and innovation efforts? And what are some things you’re doing with machine learning or GenAI in this space? 

Mike: Social determinants impact about 70% of health outcomes. Clinical care is about 10%, genetics about 20%. But social determinants cover everything from food, transportation, and shelter to how people engage with their health—adherence to care plans and motivation.

That’s why the service coordination model is so important. It builds trust first. Then it designs care plans around personal motivations—like wanting to keep a dog, visit a garden every day, or attend a museum show. These are real examples.

We need to understand what impacts those motivations. I like to call it “micro social determinants.” The macro ones are where you live, education, resource access, etc. But the micro ones are things like: do you have a primary care doctor? Can you get to appointments? Do you have a reconciled med list? Can you follow your meds? What’s your functional status?

Because if you have three or more chronic conditions, you cost about 50% more. Add one functional limitation—and that jumps to 330%. That’s about 5% of patients consuming 25% of healthcare spending. They trip, fall, and go to the most expensive sites of care.

So home safety—clutter, lighting, cords—all matter. Caregiver presence and quality matters. Your own goals and motivations matter. These are social determinants.

Another big insight from my career—when I was at AARP, we did a study on health literacy. The doctor sees me, puts on a blood pressure cuff, and says “119 over 70-something.” I ask, “Is that good?” He says “Yeah,” but it means nothing to me.

People over 65 are the least health literate—but when they are literate, they’re the most adherent to care plans. So again, that supports a social determinants and relational care model—to reduce spending on the highest-cost patients.

That’s what I get excited about in data analytics. I don’t think we’ll ever get to a point where we have social determinant care pathways like clinical ones—like in cancer, where you try drug A, then chemo B.

Nonclinical care has so many variables—social, financial, environmental, motivational—but maybe we can get close.

Q: So in your journey, what have you been experimenting with or piloting in terms of new technologies like GenAI or AI in this space, or Internet of Things—devices to keep this patient population safe and risk-free?

Mike: Appreciate that. Yeah—so first, machine learning is my top priority for innovation right now. Just like I said before: how can we take all the data we’re collecting on social determinants, the referrals we make to local community programs, and the efficacy of those programs?

We often know the best home health providers in the area. Just last month, a woman had bedbugs, and we knew Catholic Charities has a furniture bank that helps with new furniture. So how can we take both the referral and the result information, the social determinant data, and model it into efficacy?

Because that’s going to be our pathway into managed care programs. The biggest challenge for our industry is that we can’t take risks within managed care yet—our data game isn’t strong enough. When we combine clinical care and nonclinical care, it’s like baking a cake and trying to take the eggs back out. What part was the doctor and what part was us? It’s mostly us—but we need data to prove it.

So that’s the first piece. And to get that data, we’ve tried using chatbots and other engagement tools. So far, we’ve learned that where humans struggle to get other humans to communicate with them, AI chatbots tend to do worse. So we’ve gone back to using simple text message reminders: “Is there anything you need to tell us this week?”—things like that.

As for in-home technology, I’ve gone on a bit of a journey. We tested things like Alexa, sensors, and other tools. That helped us narrow down the data we really need to know if someone’s well or not. I think it’s about identifying when someone is active when they usually wouldn’t be, or when their activity looks different than normal.

I used to think about multiple sensor systems. But recently, I saw a very elegant solution that uses an AI chatbot avatar interface paired with RFID tags in shoes—50 cents apiece. Versus more complex sensor systems, can I get 60% of the data that gives me 80% of the information I need, for 10% of the cost? That’s the goal. There’s just too much data out there.

Fall prevention versus fall detection—that’s key. Anything that motivates people around exercise or engagement, that’s where we want to stay ahead. You can see it in healthcare spending: when someone falls, they start a downward spiral. That’s when all the spending happens. So anything that helps with preventative wellness is huge.

Q: That’s very cool. And you’ve mentioned broadening clinical care, Mike—you were talking about social prescribing. Can you tell us what that means to you?

Mike: Yeah, I just heard that term today, which I think is neat. In Canada, where I’m from, doctors will prescribe National Park passes. In England, they even have a Minister of Loneliness.

The joke I always tell—and maybe one listener will get this—is: “Minister of Loneliness is not the name of the new Morrissey album.” That’s my 1980s joke.

But seriously, I think social prescribing is taking off. I heard a great story on NPR today—Kaiser is supporting an initiative around this. The model is really about understanding your motivations. Why do you want to stay healthy? Why do you want to stay engaged?

What’s really important for people in their 70s, 80s, 90s is to have a strong sense of purpose. Why do you want to stay well? Maybe to see your grandkids grow up. Or to stay in your home. Maybe you want to maintain your garden. The number one reason people move from their home into another home is home maintenance—cooking, cleaning, that sort of thing.

As you age, small frictions become big obstacles. I woke up today and my back hurt—it sucks, but I got through it. For older adults, those frictions increase. Supportive services can reduce the friction, take burdens off their shoulders, and help them return to their baseline.

But you can’t do that without knowing the person and what drives them. Taking your pills every day—it’s not about liking how they taste. It’s about what motivates you.

If we start there and build a partnership, speak to someone in a language they understand—then we can make a difference. I can’t pretend to be a doctor—I don’t know the medical language, no matter how many episodes of ER I’ve watched. But we need to meet people where they are.

All healthcare is local. All social work is local. I think today’s technologies have great promise in expanding these highly successful, local, relational models. That’s what I’m excited to see.

Q: That’s amazing. So as we come to the close of the podcast, Mike—when you look ahead, based on all the innovation and transformation happening in this space—what do you see coming our way? 

Mike: Wow. Well, it’s funny with AI right now, isn’t it? Every 8 months, it seems like there’s a new revolution in capability. I used to be very cynical about it. I’m a marketing professional—my background is in direct marketing.

Then came customer relationship marketing—because consultants needed something new to sell. So I looked at AI and thought, this is just machine learning, right? It’s been around forever.

But when I started thinking about AI as pattern recognition, I began to see the bigger picture. Where else do we find patterns? We find them in nature—in fractals, in repeating structures. AI taps into that same concept of pattern recognition. It’s fundamental.

I don’t think it will ever become sentient—that’s carnival barkery. But I think it has promise. Agent AI is interesting. I haven’t seen it work properly yet—but if we can automate prescription renewals, appointment scheduling, or even coordinating a ride to the doctor—that’s big.

If we can reduce the frictions that prevent people from getting back to baseline—that’s where it’ll be most successful. And most importantly, AI should maximize human time—what we’re doing right now: having a conversation. That’s where the value in healthcare will be—freeing up more time for this.

Q: Absolutely. You know, I think the more help we can get from tools like AI coding, the better. We’re even seeing our clients ask, when we start a project, “Do your people use AI coding tools?” We’re now selecting people who are good at using those tools because some say it can make them up to 100% more productive. 

Mike: And I think there’s a democratization happening with AI. A lot of what I’m seeing is like everyone inventing the same thing at the same time, everywhere. It’s like how the light bulb and the steam engine were invented around the same time in different places—because innovation opened adjacent doors all over. That’s what’s happening now.

But unless you co-create with the people you aim to serve, you have no load around your system. So just a call to action to anyone developing solutions in our space: co-create with the patients. Co-create with the customers. The UX will be simpler, the data will be simpler, and you’ll be far more effective in selling it through.

Q: Mike, on that point, please talk to us about imparting—about your concept of entrepreneur-in-residence. I’ve talked with you about that, and it’s a very successful program. Please share.

Mike: Thank you for bringing that up. I didn’t have it written down, but yeah. In my position, I get a lot of calls from people asking for advice in the aging, longevity, or age-tech space. And by the way, I think we should get rid of the term “age-tech.” I haven’t found a better word yet, but just because you’re of a certain age doesn’t mean you need special tech.

One of the biggest challenges we face is change management. We’re largely a reactionary workforce. We don’t know what we’re walking into every day. If you want to create solutions for our space, you really need to fall in love with our problems before coming up with a solution. That’s part of human-centered design—having deep, embedded experience with those you aim to serve.

So we have a program at our Glenwood community in Marietta, Ohio—a very historic community. We have cottages, independent living, assisted living, and 15 minutes away we have Harmar Place, which is skilled nursing with memory care.

We offer a two-week program where you can come live with us. Week one, you formally shadow different job roles. Week two is kind of a “choose your own adventure.” We give you a persona—like you’re a new resident in independent living. Your persona has specific traits. Walk into the dining room, sit down, feel nervous because no one’s sitting with you.

Our residents are wonderful—they’ll sit with you and talk with you. Make friends. Get to know them. See who they are. If you make enough friends, maybe you can test your prototype or do user group testing. But it’s not going to work unless you can embody the experience and make friends. You’ll learn why people don’t have time—and what conditions make change possible.

Q: Yeah. You immerse yourself in the setting, then pick a problem to solve, and co-create. 

Mike: Exactly. And we’ve had a lot of fun with it. We’ve been running it for over a year. A lot of the people come from places like New York City. I think half of it is because they like the idea of living in a two-bedroom, two-bath apartment in a peaceful setting for two weeks. But now they’re starting to collaborate and use the experience as a foundation. I love seeing that happen.

I encourage any senior living provider to start a program like this. And any developer—look for these opportunities.

Q: That’s amazing, Mike. Thank you so much. This was a very exciting discussion. Wishing you all the best and hoping to stay in touch.

Mike: I invite everyone to check out unitedchurchhomes.org. For our entrepreneur-in-residence program, the email is [email protected]. We also have our own podcast series—abundantagingpodcast.com—and our Center for Abundant Aging, which champions ending ageism, spiritual wellness (which we didn’t talk about today), and rediscovering purpose. That’s at abundantaging.org.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]   

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

How Providence is Designing the Future of Healthcare with AI Beyond Automation

How Providence is Designing the Future of Healthcare with AI Beyond Automation

In a recent episode of The Big Unlock podcast, Sara Vaezy, Chief Transformation Officer at Providence, joined hosts Rohit Mahajan and Ritu M. Uberoy to discuss what it takes to design truly AI-native healthcare. With a career spanning healthcare policy, consulting, and digital innovation, Sara offered a candid and nuanced view of how Providence is leveraging responsible AI, reimagining care workflows, and incubating tech-driven solutions to meet the evolving needs of patients and caregivers.

Rethinking Consumer Experience: Frictionless, Personalized, Proactive

Providence’s digital transformation efforts are centered on improving both patient and caregiver experiences by eliminating friction, enhancing personalization, and enabling proactive engagement.

We really need to make finding our services and then transacting with us easier,” Sara noted. Whether it’s booking appointments, accessing financial counseling, or simply creating an account, patients should face minimal barriers. One of Providence’s priorities is enabling online scheduling for any bookable service—an effort aimed at meeting modern consumer expectations.

At the core of this strategy is personalization. Providence serves over five million patients annually across seven states, each with diverse needs and expectations. Sara emphasized that a one-size-fits-all approach no longer works. “Each person is different,” she said. “We need to recognize how important it is to speak to people in a way that keeps them engaged.”

Message Deflection Through Conversational AI

A key initiative that Sara highlighted is Providence’s use of conversational AI to deflect incoming messages that would otherwise burden physicians’ inboxes. The health system receives 6–7 million patient-generated messages annually, most of which are routed to physicians’ in-baskets.

Instead of optimizing around managing these messages, Sara and her team took a step back to ask: Why are patients sending these messages in the first place? What they found was that patients often couldn’t find the information they needed or complete basic tasks like booking appointments or understanding bills. Providence built a conversational and navigation platform to help patients resolve these issues in real time—without involving a physician.

This upstream solution has resulted in a 30% deflection rate, and Providence aims to deflect 2 million messages annually in the next few years. “It helps our patients get their needs met immediately, as opposed to having to wait 24 to 48 hours for a response,” said Sara. The success of this approach lies in combining AI agents with thoughtful product development, not simply layering on features.

Building a Digital Workforce: It’s Not Just About Automation

Sara cautioned against narrow interpretations of AI as merely a substitute for human labor. “With AI agents, it’s not just about automating the dull work,” she said. “It’s about doing things better.” Rather than automating low-value tasks for the sake of efficiency, Providence focuses on redesigning entire workflows for higher impact. “We don’t want to just automate crap,” Vaezy added bluntly. “We want to rethink processes from the ground up.”

This includes developing agents that can do things humans cannot—like analyzing massive datasets to identify the right individuals for targeted care outreach. “No human can parse through 10 or 20 million individuals to find the 1,000 people who need specific care,” she said. “AI can do that, and that’s where we see real value.”

Startup Incubation: DexCare and Praia Health

Providence has not just adopted new technologies; it has built them. Sara shared how the organization incubated and spun off two companies to address gaps in healthcare infrastructure.

DexCare, launched in 2021, focuses on supply-demand matching for on-demand care—ensuring patients find the right care, at the right time, in the right place. It helps patients discover appropriate services while balancing capacity on the provider side.

In 2024, Praia Health was launched to drive engagement through personalization. The platform helps deliver individualized digital experiences based on patient needs, preferences, and behaviors, rather than offering generic interactions.

These startups, both backed by venture capital, now operate independently while continuing to power Providence’s consumer-facing services. Vaezy credited earlier investments and organizational foresight during more financially stable times for enabling these ventures.

Designing for the Future: AI-Native Thinking

Looking ahead, Sara believes the next wave of innovation will require deeper integration of AI into business processes—moving from substitution to reinvention. “We’ll start to see more focus on what it looks like when something becomes AI-native, versus just being a tech overlay,” she predicted. For example, while ambient listening tools in clinical settings are generating excitement, Sara emphasized the importance of rethinking entire workflows to support these tools, rather than simply inserting them into outdated systems.

Another emerging area is observability—how organizations track, validate, and monitor AI systems in real-time to ensure safety and performance. “If you’re trying to run an unsupervised, non-deterministic model, you better have systems in place to make sure it’s not going rogue,” she said.

Responsible AI and Industry Accountability

Despite the excitement around generative AI, Sara urged caution and accountability. With increasing autonomy and the rise of AI agents, she emphasized the need for human-centered governance frameworks.

“It’s almost like fighting gravity,” she said. “Our job is to make this transition as responsible, humane, and ethical as possible.” She drew parallels to how consumers once expected to own their data—an ideal that faded in the face of corporate data control. “Let’s not miss the mark again,” she said. “We know this is going to happen. Now we have to ask: How do we do it right?”

Final Thoughts

Sara Vaezy’s insights offer a playbook for health systems navigating the shift to AI-native care delivery. Providence’s approach—centered on human needs, supported by intelligent systems, and grounded in ethical foresight—offers a compelling model for transformation.

By deflecting physician inbox overload, incubating purpose-built startups, and redesigning workflows with digital agents, Providence is not just implementing AI—it is rearchitecting healthcare delivery for the future.

As Sara said, “It’s not about reducing messages. It’s about the full experience.” In a rapidly evolving healthcare landscape, that mindset may be the key to unlocking AI’s true potential.

Building Value Through Real-World AI and Smart Technology Adoption

Season 6: Episode #172

Podcast with J.D. Whitlock, Chief Information Officer, Dayton Children’s Hospital

Building Value Through Real-World AI and Smart Technology Adoption

To receive regular updates 

In this episode, J.D. Whitlock, Chief Information Officer at Dayton Children’s Hospital, discusses how a smaller pediatric health system is embracing digital transformation and generative AI while navigating resource constraints.

Mr. Whitlock shares how platforms like Epic, Workday, and Microsoft are enabling innovation from within, especially through features like ambient documentation and coding assistance. With a fast-follower mindset, Dayton Children’s focuses on adopting proven tools from peer organizations rather than being the first to experiment. Mr. Whitlock emphasizes the importance of balancing hard ROI with softer benefits such as improving physician satisfaction and reducing burnout.

He also discusses the challenges of innovation in pediatric care, where many AI tools are still designed with adult medicine in mind. From building data infrastructure to enabling smarter imaging through a vendor-neutral archive, Mr. Whitlock highlights the importance of governance, strategic procurement, and cross-functional collaboration in delivering sustainable innovation. Take a listen.

Video Podcast and Extracts

About Our Guest

J.D. Whitlock is the CIO at Dayton Children’s, where he leads a team of 140 including Infrastructure & Operations, Data Services, Cybersecurity, Project Management, Workday ERP, and Epic EHR supporting a $800M pediatric integrated delivery network. His previous role was VP, Enterprise Intelligence at Bon Secours Mercy Health, a $9B integrated delivery network, where he led teams focused on Enterprise Data Warehouse, Epic EHR Analytics, Population Health BI, and Data Management. He started his healthcare career in group practice management and managed care before transitioning into healthcare IT roles, where he has broad experience spanning government, vendor, and private sector provider organizations over the last 30 years.

A retired USAF Lieutenant Colonel, J.D. started his military career as a Surface Warfare Officer in the Navy for seven years, including service as Gunnery Officer onboard the destroyer USS Paul F. Foster (DD-964) during Desert Storm. After completing a master’s degree in healthcare administration, he transitioned into the Air Force Medical Service Corps, where he served in a variety of healthcare management roles, including a deployment to Bagram Airfield, Afghanistan, as Commander of the Patient Administration Division supporting Operation Enduring Freedom in 2007.

J.D. is the owner of Whit’s End Consulting, providing after-hours HealthTech and digital health consulting services from the perspective of a practicing health system CIO.

J.D. holds a BA in Mass Communication from George Washington University, a Master of Public Health in Health Policy and Management from UCLA, and an MBA in Management Information Systems from the University of Georgia.


Q: Hi, JD. How are you doing? It’s great to have you on the podcast. Awesome. So JD, as you might be aware, this is The Big Unlock podcast, which was started by the founder of Damo Consulting, Paddy Padmanabhan. We’re now in Season 6 and north of 160 episodes. We’ve come a long way since this podcast started.

I’m Rohit Mahajan, Managing Partner and CEO of BigRio and Damo Consulting. Super excited to have you as our guest and looking forward to diving into some topics. Would you like to start with an intro?

JD: Sure thing. I’m JD Whitlock. I’m the Chief Information Officer at Dayton Children’s, a small pediatric health system in southwest Ohio. I’ve had a pretty long career in healthcare IT—30 years now in healthcare. I’m a retired Air Force healthcare administrator.

I’ve also spent time in larger adult private sector systems like Bon Secours Mercy Health, where I focused a lot on data and analytics. Now, as CIO, I do a little bit of everything IT at Dayton Children’s.

Q: That’s great to know, JD. A couple of questions—just curious. What attracted you from being in the military, in the Air Force and Navy, into healthcare, where you’ve stayed for a long time now? And where are you headed? That’s one part. And second, please tell us a little more about your health system. 

JD: Yeah, sure thing. You mentioned Navy and Air Force—yes, I did start out in the Navy. I wasn’t doing healthcare there; I was doing Navy things, driving ships around.

Then I got a master’s in healthcare administration and started healthcare work in the Air Force. The job I had there was mostly in healthcare IT management.

So really, by the end of my Air Force career, I was doing very similar things to what I do today. And a little more on Dayton Children’s—we’re on Epic. We’re big enough to be on Epic and Workday, which I think probably factors into some of the things we’re going to talk about. 

We’re small compared to most health systems. So what does that look like?

It means we have to do a lot of the same things that bigger health systems do, but it can be challenging to have the resources—people and dollars—to get all those things done.

Of course, when you bring your sick or injured child to Dayton Children’s, you have the same expectations for quality and experience of care that you’d have at a larger children’s hospital—like Cincinnati Children’s or Nationwide Children’s in Columbus.

So yes, the challenge is keeping up with larger health systems, but with fewer resources.

Q: I see, I see. And an increasingly difficult environment lies ahead. So I’m sure there are more challenges on the way, and I’m sure the leadership is already thinking about how to navigate those challenges—especially, and we’ll get to that—no podcast is complete without AI. We’ll talk about that in just a moment.

But before that, what I would like to ask you is—you mentioned that you are on Epic and Workday. So please tell us a little bit more about how that drives your innovation, or let’s say, the consumerism from the digital front door perspective. Any initiatives like that?

JD: Sure thing. So in both cases, we spend a lot of money for the care and feeding of those platforms—both in dollars to the vendor and in terms of all the labor that we need to put into them. That’s the bad news.

The good news is we have best-in-class platforms in both cases, and we can do a lot of innovation just by optimizing within these platforms, including some of the generative AI features that both vendors are doing a very nice job implementing into their platforms. That’s very exciting.

We’re early-ish stage with some of that, but the point is—it’s a lot easier to implement these features from within the platform than try to bolt on new things. In some cases, we’ll be bolting on new things, like ambient, and maybe some autonomous coding and some other things.

I’m not saying we won’t do that at all, but probably 90% of what we would do with generative AI would just be from Epic—or I should probably also throw Microsoft in the mix. We’re a Microsoft shop, so we’ll be using some Microsoft tools also.

 Q: Yeah. So could you talk to us, JD, about some of the generative AI use cases that you perhaps are already looking at or might be on the roadmap of these vendor partners that you are going to be adopting? 

JD: Sure. Well, one obvious one is ambient. Most health systems—if not fully in production—are at least piloting or about to pilot something with ambient. I think very soon here, having some ambient solution will be an expectation from providers. And health systems may have difficulty recruiting new providers. And of course, as we have more challenges with physician shortages, that’s going to be a challenge.

One dynamic at Dayton Children’s is, of course, we need to successfully hire pediatric specialists. And they typically are getting out of their pediatric specialty fellowships at large academic medical centers. To convince them why they should move to Dayton, Ohio, we can’t be at a competitive disadvantage to some of the larger facilities. If we are, for example, not using ambient, we’d like to be fast followers. We’re not going to be the first to do things. We’ll leave that to the academic medical centers and some of the truly new things that they’re developing—both on the clinical side and the digital health side.

One of the nice things about being an Epic customer, of course, is there’s such wonderful collaboration between the whole Epic community. If you do something innovative in your Epic build, you go to the Epic conference, you present it, and other people can use that. That’s sometimes what Epic will just build into the next version of Epic. So an awful lot of that goes on all the time. And Epic is rolling out so many new features so fast, it’s actually difficult just to keep up with all the new features that are coming from Epic.

Q: That’s true. It’s a large system, JD. So how do you separate the wheat from the chaff? That’s something we were kind of hitting on before we started the podcast. What are your thoughts on that? How do you decide what is critical and core, and what can be done later or perhaps doesn’t need attention right now? 

JD: Sure. So as a general concept—just good governance, right? And not chasing after, as we like to call them, the “bright, shiny objects.” Even with core generative AI, you’ve always had that problem. Somebody goes to a conference, they see something that looks cool—and it may be cool—but there’s not enough return on investment to spend the dollars we don’t have on that thing.

So we’ve had that challenge for a long time. I would say generative AI has ramped that problem up a few notches because there’s so much hype. You have to be careful—not just about wasting money, but also the additional considerations that come with generative AI that we didn’t always have with other things. Things like ethical considerations and medical-legal concerns. So we need to pay a lot of attention to that.

I try to stay up on all this, of course. And when I listen to very smart people who spend their entire lives focused on generative AI, they often talk about the investment bubble. Two things can be true at the same time: One, there’s amazing science and capabilities advancing very quickly. And two, a lot of the investment money pouring into this is going to be bad investments because nobody’s going to pay a gajillion dollars for that thing you built.

So that’s where you have to be very careful. Now, how do we handle that? Well, we handle it like we always have—by asking hard questions about ROI. And sometimes we do things that have more soft ROI than hard ROI.

Ambient is a great example. Reasonable people can disagree about the hard ROI, but there’s really no question about the soft ROI—keeping our providers happy. You hear story after story: “I was about to retire early,” “I was burned out,” and “this really brought back the joy of practicing medicine.” Pretty much every system that’s implementing ambient gets dramatic stories like this from providers.

Soft ROI is important too. You just can’t buy everything that has soft ROI—you have to be judicious.

Q: We had touched upon using some of the new tools that are coming out for enabling coding. What are your thoughts on some of these tools, JD?

JD: Yes. This is an interesting space. It may be something we work on with additional vendors. In fact, we’re about to go live next week with Epic’s professional billing—what I believe is called the DB Coding Assistance. It’s a lighter-weight AI solution aimed at making our PB billers’ and coders’ lives a little easier with some tools from Epic.

There’s a spectrum of billing complexity—from professional billing to hospital outpatient and inpatient. From what I understand, inpatient is still too complex for full autonomous coding. But in the hospital outpatient space—that middle ground—autonomous coding, thoughtfully applied, can really help our coders and billers be more efficient. We’re exploring some of those vendors to see if there’s a good fit for us.

Q: That’s great. So, as a smaller health system, how do you approach innovation? How do you keep up with the larger systems and still deliver quality care? 

JD: Sure. Something else—there’s a term commonly used in the Epic ecosystem: “imitate to innovate,” right? If you can get past the concept of not being proud about implementing something that somebody else developed someplace else—that’s really the answer. We like to say we want to be fast followers. Most people in IT are familiar with Gartner’s hype cycle—the peak of inflated expectations, the trough of disillusionment, and the plateau of productivity. We’ll let others go through the trough of disillusionment. We want to be there for the things that actually work.

We’re not just rolling the dice on whether something will work. No, that worked. This thing worked at another children’s hospital. And we know those people—we have really good relationships with pretty much all the CIOs and CMIOs at the other children’s hospitals. We go to conferences and talk to each other—“Oh, that new generative AI feature from Epic worked wonderfully for us,” or “that one didn’t work so well—it wasn’t a good match for pediatrics,” or whatever the case may be. We talk to each other and increase our confidence. Nothing’s ever 100%, but we’re more confident that it’s worth the effort.

Q: Right. And JD, you’ve been at health systems that weren’t pediatric-focused as well, right? So what’s the difference? I’m curious—in the world of pediatric hospitals, how are things different compared to other health systems?

JD: Sure, thanks. Some things are different with pediatrics. It’s unfortunate, but it also just makes sense—the way the world works. When you have innovators and venture capital funding innovation, a lot of the dollars go to adult medicine because that’s where more of the money is. Pediatrics sometimes plays second fiddle.

Maybe Epic rolls out a new predictive algorithm that works better for adults than for pediatrics. That was true for the sepsis predictor. I remember a pediatric CMIO talking to me about why that was. So we just have to be cautious.

Other examples—imaging. Now we’re talking more predictive than generative AI. Some of these are technically generative, but there’s a lot of FDA-approved, highly effective new imaging tech powered by AI. I was talking to our radiologist about that, and at their conferences, they’ve noticed there hasn’t been much for pediatrics yet. A couple things—bone age prediction, maybe one other—but that’s about it.

So sometimes we just have to wait. In other cases, there are people doing innovative things targeted at pediatrics. We’ve been looking at a couple of NICU-focused solutions—for a better parent experience. Your precious little new baby, sometimes very tiny, is in the NICU. You have to learn a lot quickly—talk to the doctors and nurses and figure out what that all looks like. How can we make that experience better?

Also, we’re an ACO—we want to make sure we’re spending our dollars wisely. We want kids in the hospital when they need to be, and home when they can be. Some solutions around tube feeding, oxygen—where we can send infants home earlier than we otherwise could with better remote monitoring and communication tools. In some cases, there’s real innovation going on that’s very specific to pediatrics.

Q: That’s great to know. You also mentioned Workday, along with Epic, as a major system. Have you seen anything on Workday’s roadmap that you’re considering? 

JD: Yes, we were just looking at this yesterday in our Workday executive governance meeting. We asked our account team to put together a chart of all the generative AI features Workday has. There were a lot—it all had to fit on one slide with pretty small fonts. We color-coded them—what we’re licensed for and using, what we’re licensed for but not using yet, and what we could be doing but aren’t licensed for.

One big difference between Epic and Workday when it comes to AI: Epic has a deep partnership with Microsoft. That’s where the generative AI and cloud compute happens—in Azure. Epic is hosted on-prem for us. A lot of Epic customers are still on-prem. Workday, by contrast, is built with modern cloud architecture from the ground up. They don’t need to partner with anyone—it’s just built into the platform. Both vendors are doing AI differently based on their system architecture.

Q: So again, JD—just a curious question because I’m trying to build a picture in my mind. Let’s say Epic and Workday are two major systems that are clearly top of mind. Are there two or three other systems, not in the same space, but in different domains, that are also driving your AI or GenAI roadmap?

JD: Sure. For health systems, another very strategic area is your PACS vendor. For modern PACS vendors, you want them to plug into all the AI tools that are coming. In some cases, they can do that natively. In others, there’s middleware that adds AI features. You want to be able to add that capability easily.

Then there’s the vendor-neutral archive—getting all the images in one place. We haven’t always done a great job with that. If a radiologist ordered and read the image, it went into PACS, but other images—ordered and read by other providers—sometimes get squirreled away. That’s not ideal, especially if you want to apply AI across images. A vendor-neutral archive is typically a better architectural solution.

One of the most strategic acquisitions we’ve made in the last seven years was PACS. When I got here, we were already on Epic, and Workday was just starting. But PACS—we were replacing an old legacy system. I knew we needed a PACS and VNA combo that would be future-proof. We selected Sectra, which has long been considered best in class, and we’ve been happy with them.

There aren’t a lot of pediatric-specific AI tools yet, but we have good confidence in our direction. We’re doing well getting the other images—like point-of-care ultrasound—into the VNA. So as AI tools become available, we’ll be able to implement them easily.

Q: You mentioned the vendor-neutral archive, and that reminded me: for AI, we need data, right? And we need data engineering on top of that. But data’s often siloed—Epic has its data, Workday has its own, PACS has its own. How do you approach enterprise-wide AI that cuts across systems or functions? 

JD: Good question. If we had more money and more time—and maybe if we were a big academic medical center—we’d be spending more on a true enterprise data warehouse. Honestly, we don’t really need that at Dayton Children’s. The vast majority of our reporting and analytics lives in Epic.

That said, we are dabbling with Microsoft Fabric, because that’s where Epic is headed for the cloud. We’ve been doing Power BI for a while. For our enterprise scorecards, we bring in Epic data, Workday data, and other sources to build dashboards for leadership.

Another example—patient survey data. We take survey data from our vendor, mash it together with Epic data, and build dashboards. That helps us drill down on metrics like Net Promoter Score, which we’re proud of. And we’ve done analytics around that—asking why certain patients in the ED at certain times aren’t satisfied. You can’t tell just by looking at the survey data—you need the Epic data too. Then you can better implement fixes.

Q: That’s very thoughtful and insightful. JD, I know you mentioned that you also do some consulting. Can you tell us more about the kinds of engagements you take on and what excites you? 

JD: Yeah, I do a little consulting on the side, after hours. I joke with my boss that it makes me a better CIO—it helps me stay connected. I talk to people—sometimes investment companies—who are trying to decide whether to invest in a particular software solution. They want to talk to someone actually using it.

Sometimes people have a new product idea and want feedback from someone like me. I see things coming into the market—vendors acquiring tools and building platforms. Most of the work I do is one-off expertise. I’ve been doing this for a long time.

Occasionally, I help tech companies on an ongoing basis—helping with go-to-market strategy and how to sell into health systems. That kind of thing.

Q: Thank you, JD. As we wrap up, are there any other thoughts or things you see coming in the future that you’d like to share? 

JD: One last thought—it always comes down to good governance. I talk to other CIOs and CMIOs who struggle with too many requests. “How do we deal with all these requests?”

Something that’s important—but not fun to talk about—is acquisition policies and governance. People are getting wrapped up in all the new GenAI stuff. You need to think hard about the ethical and medical considerations and build those into your evaluation and procurement processes.

What I see a lot of people doing is starting 17 new AI committees. And I think, who has time for that? It’s better to work AI into your existing governance structures and procurement policies. But those policies have to have teeth. You can’t let everyone buy any IT thing and toss it over to IT to implement.

Then IT ends up unable to do the core things we’re supposed to be doing because we’re trying to plug in new tools that don’t fit the architecture.

Q: Understand. Thank you, JD. This has been a great conversation—really appreciate it.

JD: Thanks for having me. Hope we can continue the conversation in the future.

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Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Aligning AI Fundamentals with User Experience in Pharma

Season 6: Episode #171

Podcast with Alicia Abella, AI Product Lead, Novo Nordisk

Aligning AI Fundamentals with User Experience in Pharma

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In this episode, Alicia Abella, AI Product Lead at Novo Nordisk, discusses how she is helping drive responsible AI adoption in the pharmaceutical industry. She shares her early experiences in AI, starting with her PhD research at Columbia University on image processing and natural language processing. 

At Novo Nordisk, the current focus is on applying AI to commercialization functions including – marketing, legal, and HR – beyond it’s traditional use in drug discovery. Alicia highlights key use cases such as generative AI for knowledge search, content generation for marketing campaigns, and traditional AI techniques for deriving insights about healthcare providers. She also emphasizes the importance of applying a product mindset to AI development by evaluating user needs, business value, and compliance from the outset.

Alicia notes that adding effective governance can help innovation move in the right direction. She also talks about an internal AI Ambassador Program and emphasizes the importance of designing intuitive AI tools to increase adoption. She concludes by discussing future trends in AI, including contextual intelligence, user-centric design, and the opportunity for AI to enhance, rather than replace human decision-making. Take a listen.

Video Podcast and Extracts

About Our Guest

Alicia Abella, Ph.D., is the AI Product Lead at Novo Nordisk where responsibilities include developing strategic vision and guiding ethical AI applications in the healthcare sector.

Prior to this role, Alicia served as Chair of the Technical Advisory Council and Executive Board Member at the Consumer Technology Association, contributing to key strategic initiatives and industry leadership. At Google, Alicia held positions as Global Practice Director for AI/ML and Managing Director for Telecom, Media & Entertainment Industry Solutions, focusing on sales strategies and innovative solutions. Alicia's extensive career at AT&T Labs included leadership roles in advanced technology realization and operational automation.

Educational credentials include a PhD in Computer Science from Columbia University and a BS in Computer Science from New York University.


Q: Hi, Alicia, welcome to the Big Unlock podcast. It’s great to have you here. This podcast is now in season six, Alicia, and you’re looking towards an exciting conversation here. I am Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting, and would love an introduction from your side. 

Alicia: Hi, Rohit. Uh, lovely to be here, and thank you so much for the invitation. Well, thank you. Yes, I’m Alicia Abella, and I am the AI Product Lead with Novo Nordisk. I joined Novo Nordisk in November of 2024. I will say that I am new to pharma and was very intrigued by the opportunities that pharma has for AI. My whole background since graduate school has been in AI in some form or fashion, so we could talk a little bit about that and where I am. And I’m from Morristown, New Jersey.

Q: Absolutely. That is awesome that you’re new to pharma and you’re kind of looking at it from perhaps multiple different experiences that you already have. So please tell us, Alicia, how did you get started? What drew you to AI and now to pharma, and what are some of the experiences that you’ve had before you got here? 

Alicia: Yes, happy to do that. I would say that my involvement with AI started rather serendipitously in graduate school. I was a PhD student at Columbia University and I was looking for an advisor—specifically a tenured advisor—because I knew as a student that if you signed up with a tenured advisor, you wouldn’t run the risk of them not getting tenure and then having to move to another university to follow your professor.

So the professor I worked with on my thesis was in the area of computer vision and image processing. I also had a co-thesis advisor who was in natural language processing, so I had a very early experience in that area that now is so popular with large language models and AI. This was a period where the technology was using different techniques, algorithms, and approaches than we do today. But still, there was that sentiment that artificial intelligence could be used to do many things and assist people in discovery.

The actual work I did for my PhD thesis was in the life sciences and healthcare industry. Ironically, even though I’m new to pharma now, I feel like I’ve come full circle. My thesis involved developing a software system that could do image processing on radiographs of human kidneys and the urinary tract system—automatically detecting calcific densities and kidney stones—and then automatically generating radiology reports.

Part of my thesis was to see how well a machine could do that compared to a radiologist, and it turned out it did pretty well. And this was in the mid-nineties.

That experience propelled me into AI, and especially the work I did on my thesis in natural language processing led to an opportunity at AT&T Bell Labs. I got a job in their research organization specifically doing speech and natural language processing research. What I think most people don’t realize is just how long research in this field has been going on. We often think that large language models and ChatGPT just burst onto the scene, but in fact, the foundational work has been going on for decades.

When I joined Bell Labs in the mid-nineties, they had already been doing speech and signal processing research for nearly half a century—40 to 50 years. That’s a humbling experience because you realize just how difficult these problems are.

So that was a challenge, and I spent a lot of my career—25 years—at Bell Labs doing many different things. But the part that still resonates with me is the work I did initially on spoken dialog systems for customer care. 

So that’s a little bit about my initial beginnings with AI. And then yes, after a long career at AT&T, I took on a role working at Google. Because of my long career at AT&T, Google—at the time, around COVID in 2020—was standing up an entire organization devoted to different industry verticals. They were hiring a market lead, a managing director for the telecom, media, and entertainment industry vertical. I was recruited for that role and joined Google in August of 2020, right in the middle of the pandemic.

It was interesting because Google Cloud at that time was growing very rapidly. They really wanted to go after some of our strategic customers in the telecom space. Having spent so much time at AT&T, I could talk the talk. I’d walked in the shoes of our customers. My role was really to talk to our most strategic senior executives and C-suite executives across all of the Americas in that industry to try to understand: What are their pain points? What problems are they trying to solve? And how could Google and Google Cloud’s products and services help them solve those problems?

In my last year at Google, before joining Novo Nordisk, I was the Global Practice Director for AI and Machine Learning. I was essentially the bridge between our go-to-market organization and our product and engineering teams that were developing the AI products that are now very much in use—Gemini, Vertex AI, and others. I was ensuring those products and features were really meeting our customers’ needs globally and across all industries.

So I went from telecom to representing all industries and from the Americas to a global role. I spent about a year in that role until I got a call from Novo Nordisk. As I mentioned earlier, I was very intrigued by the opportunity to take AI and apply it to an industry that I think has tremendous potential—to apply AI across all of its business functions.

We often hear about AI being used for drug discovery, and pharma companies are very much involved in using AI to help accelerate drug discovery. But there’s also an opportunity across commercialization functions as well, which is where my current focus is at Novo Nordisk—to bring AI to the commercialization space.

We’re trying to move from traditional commercialization techniques to thinking about how we can use AI to accelerate the work that needs to get done—whether it’s marketing campaigns, legal issues, HR—you name it. The entire organization involved in that go-to-market aspect of taking a drug, once it’s been discovered and approved, to market.

How can we use AI to accelerate that process and make it better? Make it more personalized? How do we find the right patients? There are so many applications in the commercialization space, and I think we’re only scratching the surface.

Q: Absolutely. Very exciting, Alicia. Thank you for sharing that.
As you go about this role, we talked earlier about AI adoption and change management—how do you get people to embrace it? What are you seeing in the business enterprise, and what are some of the things you’re doing to make this happen?

Alicia: That’s a great question, Rohit. When I first joined Novo, I spent the first few months—maybe a good solid three months—just going around and talking to various leaders across different business functions to understand what they were doing, what their current sentiment was, and what their understanding of AI looked like. I needed to understand where Novo Nordisk was in that journey.

It was varied. There were folks who were very excited about the prospect of AI, and others who were afraid of it—or still are—partly due to a lack of understanding and education, and partly because of the compliance and regulatory risks they know or have heard about. We’ll probably get into that later in the podcast.

I also created a survey at the time, which I sent to the marketing teams to assess their general understanding of AI and create a baseline for myself. Through that process—conversations and survey results—I realized there was a need to demystify AI for many people. I also needed to develop very strong relationships with our legal and compliance departments, to involve them very early in any AI solutions we were thinking of developing. That way, everyone would feel safe and confident that what we were building wouldn’t create risk for the company.

So I came up with and launched, just two weeks ago, an AI Ambassador Program. I wanted to find and engage the people who were excited about AI, wanted to learn more, and wanted to be part of a community that could share that knowledge with their peers.

It was important to me that these ambassadors represented all job functions within the enterprise because they know their day-to-day work better than I do. They know where AI could be applied. They could become a kind of flywheel for me within their own organizations.

I put out a request to the organization for volunteers, and the response was overwhelming. I surpassed my expectations in terms of the number of ambassadors I hoped to recruit, and now I have a big cohort.

Now the real work begins—how do we equip the ambassadors with the knowledge and education they need? My goal is to awaken their curiosity about AI and inform them in a way that is relevant to their context. I want to give them a broad understanding of AI, what’s out there, what’s coming, and what’s on the horizon. Get them excited. Get them thinking about how to apply AI to their day-to-day work so they can bring that knowledge back to their peers.

I think it’s really important that this happens peer-to-peer. It’s not coming from a top-down directive that says, “You must do this training.” That kind of approach doesn’t work—especially if it’s not connected to their day-to-day work. That contextual understanding is critical, and that’s what the ambassadors can bring. I can help supplement it by bringing in the outside-in perspective of what’s going on in the AI landscape today.

We also have internal tools—Novo Nordisk ChatGPT, for instance—that employees can use to query and ask questions. It’s all within compliance and legal, so it’s a safe place for them to experiment. We also have Microsoft Co-Pilot, and there’s a lot of training available there too. But my focus is to expand their thinking with a broader understanding of AI.

We launched the AI Ambassador Program last week. We meet monthly to discuss different AI topics, and I know the next topic we’ll cover will likely be use cases that are relevant to the organization. We already have a lot of AI use cases across the company—including globally—so knowledge sharing is a big part of this program too.

Q: That’s wonderful. It’s a very unique approach to increase adoption, Alicia. You just mentioned use cases—what are some of the ones you’re already seeing, or that you’ve seen other pharma companies pursue? 

Alicia: Sure. Since my focus is on commercialization, I’ll highlight use cases in that area. One of them is what I’d call using AI for knowledge search. One of the first things I noticed was how much data our marketing and insights teams have access to—whether it’s reports they generate themselves or third-party vendor research to understand how our products are doing in the market and what our competitors are doing.

There are so many disparate data sources and documents. It’s hard to find what you need. So, we’re working on using generative AI to provide a conversational interface where market researchers can ask questions, and the solution can sift through thousands of pages to return useful responses—with attribution, so they can validate the answers by going back to the original documents.

That’s one use case—market research and competitive intelligence using knowledge search.

Another is content generation. We’re using generative AI to come up with variations on ad messaging and new campaign ideas. We’re also exploring image generation and short video clips to help marketers communicate their ideas to ad agencies faster. Using GenAI in this way can help accelerate time-to-market for campaigns.

Ultimately, the hope is that we could use these technologies ourselves to create content, instead of outsourcing it.

Then, more traditional AI techniques are being used to analyze large datasets to understand healthcare providers—their habits, the types of patients they’re seeing, and who they’re diagnosing with conditions our products support. These insights help us better position our messaging and outreach to HCPs.

It’s a powerful use case that helps us reach more healthcare providers, who can then reach more patients. That’s how we ultimately expand access to our therapies.

Q: Great use cases, Alicia. Early on when we were talking about a product mindset and you know, a very disciplined way of approaching the implementations or the use cases itself. So, could you tell us a little bit about what does that mean?

Alicia: Yeah. So, when I was first recruited to join Novo Nordisk, I thought the part that intrigued me, in addition to it being a new industry for me and a great learning opportunity, was this idea of applying the product mindset to developing AI solutions for the pharma commercialization team. Because I’ve seen it too often in my history of being in technology and development, and being around technologists, that they get very excited about an idea—an idea for a product—and they go off and build it without actually taking into consideration: should we be building it?

Just because you can build it doesn’t mean you should build it, right? There’s a lot of work that goes on in evaluating and determining whether an idea should actually be productized.

So my role was to bring my experience—all the way back from my AT&T days and Google days—around a product management lifecycle mindset. Think about product management as: design, develop, test, monitor, iterate. Design, develop, test, monitor, iterate—how to do that, and how to put that kind of rigor into decision-making about what AI products and solutions we should be developing.

That’s what I’ve brought to the exercise of us picking what AI products to focus on. Because there’s limited resources, so we have to figure out and prioritize.

Step number one is: let’s understand the user need. Let’s understand and talk to those end users—those key stakeholders and sponsors—and understand the problem they’re trying to solve. Figure out if indeed you need AI to solve it. Because in some cases, you may not. So that’s part of the process.

If indeed AI is a good tool for it, then what’s the business value? Can we create a business case for it? What are the implications of building this solution in terms of compliance, risk assessment, technical feasibility? All the things you have to consider to generate and create a new product.

Bringing that process here helps us focus on developing AI products that we know will create the biggest impact and have the most value across the largest set of stakeholders.

And so that’s kind of what I’ve been bringing to Novo Nordisk and to our AI product experience—because I think that’s maybe something that any company needs. And yes, pharma is still relatively new to AI, especially in commercialization. And I think a little bit of governance, without it being too heavy-handed, can help drive the innovation and drive it in the right way for the right problems.

Q: Absolutely. And in pharma, it’s highly regulated, as we all know, Alicia, and there’s a lot of compliance. How do you tackle that aspect of it in the journey? Could you tell us how you’re approaching that as well? 

Alicia: I’m glad you asked that question because it’s one of the things I mentioned earlier about my listening tour when I first joined Novo. When I was talking to different folks, I made sure that legal and compliance were on that tour. I wanted to understand Novo Nordisk’s guiding principles and how they were thinking about AI.

We have AI principles and guidelines that we follow today. And what I’m currently involved in is working very closely with our data ethics, compliance, and legal teams—very early on.

I told them, “You’re going to be my BFF,” right? You’re going to be my best friends. Because it’s important to make sure that what we’re developing is done in a compliant manner.

What I can bring to that process and that team is an understanding of where to put those guardrails so we don’t stifle innovation. We still need them, but we do it in such a way that we manage risk while still being able to innovate.

Having a strong relationship with that team—where we both understand what we’re each trying to achieve—is important. I bring them in very early, even when we’re still just thinking about an idea for an AI solution. I say, “Look, this is what we’re thinking—are there any big red flags I should be considering?” So we can address those right at the beginning, before too much effort and resources have been devoted to developing a solution that they might later come in and say, “Oh, you can’t do that.” We definitely don’t want to do that.

That’s an important component, especially in a highly regulated industry. And I think there’s still a lot of room for innovation, even within those boundaries.

Q: Great. So, as we come towards the end of the podcast, Alicia, I’d like to ask—what are your thoughts or ideas about future trends? What do you see from your perspective? 

Alicia: I wish I had a crystal ball! But if I look into it, one area that I think will be very interesting for AI in the future is making sure that we’re marrying the AI fundamental technologies with the user experience.

Part of that is driven by my entire career—I’ve always been focused on that user-centric view. To drive adoption of any product, you have to make it usable. You have to make the experience something that people will want to use—something intuitive, easy to use—that will drive adoption.

It obviously has to solve a problem. Assuming it is solving a problem, it should do it in a way that makes it easy to interface with. I think part of what made ChatGPT so prolific in terms of adoption was how simple that interface was. It’s just a window that says, “Ask me a question.” You just type it in the way humans are used to asking questions.

So I think as we build wrappers and layers on top of these fundamental large language models, it’ll be important to ensure that simplicity of user experience remains.

That will be a trend going forward. I think one of the big tech giants creating large language models will now focus heavily on user experience.

Maybe I’m just channelling my experience when the iPhone first came out. Steve Jobs had that focus and fascination with experience. It was all about the experience—being very user-centric. I think we can’t lose sight of that.

Another trend I think we’ll see is large language models evolving beyond just text, image, and video—to start bringing in more contextual knowledge. The kind that humans bring. That’s the missing link right now.

It’ll be interesting to see what the future holds on that front. I’m a big Star Trek fan—especially The Next Generation. There’s an important character named Data. He’s a machine, an AI. All he wants to do is be human.

All of his attempts at being human—wanting to be an artist, a writer, a pet owner—everything is about the machine wanting to be more human.

I think we still have that desire—to see how we can make these machines behave more like humans, without taking us out of the loop. Of course, there’s that fear too, but that’s a whole other podcast episode, Rohit.

But there’s a lot to be excited about in the future, and I feel fortunate and privileged to be part of this experience and to see where it all unfolds.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Designing Trusted AI-First Healthcare with a Focus on Innovation and Equity

Designing Trusted AI-First Healthcare with a Focus on Innovation and Equity

In a recent episode of The Big Unlock podcast, Aneesh Chopra, Chief Strategy Officer at Arcadia shares a bold and comprehensive vision for transforming healthcare through data, technology, and public-private collaboration. Hosted by Rohit Mahajan, Managing Partner and CEO of Damo Consulting and BigRio, the conversation spans a wide range of topics, from the early days of “meaningful use” to today’s AI-enabled, value-based care ecosystem.

From “Meaningful Use” to Meaningful Impact

Aneesh Chopra reflects on the origins of the “meaningful use” program, which was designed to drive adoption of electronic health records (EHRs) through the HITECH Act. While the program succeeded in digitizing healthcare, Mr. Chopra acknowledges it fell short of transforming care delivery. Much of the technology was optimized for fee-for-service billing workflows rather than for improving clinical outcomes.

Now, Mr. Chopra sees a chance to realign health IT with the goals of value-based care. He emphasizes the need to define “meaningful use” in terms of patient outcomes, longitudinal care, and proactive health management. The renewed push, especially through the latest CMS-ONC RFI, presents an opportunity to finish what was started over a decade ago but with a clearer vision for outcomes-focused, AI-supported workflows. He urges the healthcare community to participate in shaping the future of health IT through these requests for information. “We want the technology to operate in a way that supports value-based care networks, helps consumers access their information, and enables real-time clinical decision-making,” he explains. Mr. Chopra emphasizes the need to move beyond back-office digitization to technology that enables smarter care delivery.

Introducing the “Healthcare Information Fiduciary”

One of the most innovative concepts Mr. Chopra introduces in the podcast is the idea of a “healthcare information fiduciary.” Drawing inspiration from financial fiduciary rules, this model proposes that applications and platforms handling patient data must act solely in the patient’s best interest.

In practice, this means creating a trusted marketplace of AI-enabled apps that help patients aggregate their medical records and receive personalized, unbiased recommendations. Such platforms would operate independently of the financial incentives of payers, providers, or pharmaceutical companies. “If you trust me with my information in a complex domain,” Mr. Chopra explains, “you must act in my best interest, and not based on how you get paid.” He states that this idea is already gaining traction through a voluntary code of conduct for consumer health apps, developed to encourage transparency around data use, including for de-identified data, an area traditionally excluded from HIPAA disclosures. This move toward greater openness and accountability is a step in the direction of building a full-fledged fiduciary model for healthcare data.

AI and Intelligent Workflows: Real-World Success Stories

Mr. Chopra shares compelling examples of how AI-driven workflows are already delivering tangible results. In one case, an academic medical center improved its Medicare Advantage star ratings by using conversational AI to reach out to patients, close care gaps, and ensure adherence to preventive care protocols. The campaign led to a significant quality improvement and unlocked over $6 million in incentive payments. These AI-powered agents contacted patients on behalf of their physicians, reminding them to complete necessary screenings or check-ups. By automating outreach at scale, the organization could more effectively engage patients—many of whom might otherwise fall through the cracks.

In another example, a health system leveraged AI-powered decision support tools to align with evidence-based guidelines. These tools acted as co-pilots for clinicians, reducing cognitive load and ensuring that treatment plans adhered to best practices. Though still in the pilot stage, this approach shows promise in enhancing care consistency and quality. The goal is not to replace clinical judgment but to support it with relevant, real-time data. AI tools can identify patients who match specific evidence-based criteria, flag care gaps, and help clinicians act quickly to address them. This type of augmentation could prove critical in improving care outcomes while reducing provider burnout.

Real-Time Data Through FHIR APIs

Interoperability has long been a challenge in healthcare, but Mr. Chopra is optimistic about recent progress. He points to the success of CMS’s FHIR API implementation, which is enabling near real-time access to claims data in programs like ACO REACH. This has transformed the utility of administrative data from retrospective analysis to proactive care management.

For example, advanced primary care providers working with high-risk populations are now able to detect changes in patient status within days of a clinical encounter, allowing them to act more swiftly. This real-time feedback loop represents a critical step toward building a learning health system that is both responsive and adaptive. Mr. Chopra explains that this shift reduces the lag between when a healthcare event occurs and when it can be addressed by a care team. Instead of waiting weeks or months for claims data to be analyzed, providers can now access that information in closer to real time, enabling more immediate interventions and better patient outcomes.

The Role of Public-Private Collaboration

Throughout the episode, Mr. Chopra emphasizes the importance of collaboration between the public and private sectors. His own career reflects a passion for creating handshakes and handoffs where policy creates the framework, and the private sector drives innovation.

He cites the CARIN Alliance, a bipartisan initiative he co-founded, as an example of progress in creating a voluntary code of conduct for consumer health apps. This code aims to increase transparency around data use, including de-identified data, and build consumer trust. According to Chopra, the combination of data sharing rights and an AI code of conduct will catalyze a new generation of responsible, patient-centered tools.

According to Mr. Chopra, the combination of data sharing rights and an AI code of conduct will catalyze a new generation of responsible, patient-centered tools. He also credits the efforts of bipartisan policymakers and industry leaders in sustaining progress over time. “We’ve seen administrations change, but the momentum toward smarter health data use continues,” he says. This consistency is essential for driving lasting innovation and achieving meaningful outcomes at scale.

From Vision to Action: Enabling the Future of Healthcare

Mr. Chopra closes the conversation with a rallying cry to the healthcare innovation community. He urges early adopters, across startups, health systems, and technology vendors, to raise their hands and help test, validate, and scale the tools needed to support a more equitable and efficient healthcare system. “If you see the future and you want to have a hand in bringing it to life,” he says, “we would love to tap into that talent.”

He emphasizes that meaningful transformation will require experimentation, feedback, and iteration. The public sector is opening the door with policies and programs but it is up to the private sector to walk through it and deliver results. Early adopters will play a vital role in shaping the next chapter of healthcare innovation.

This episode of The Big Unlock is more than a retrospective on health IT policy, it is a forward-looking manifesto for how data, AI, and innovation can reshape American healthcare. Aneesh Chopra’s insights serve as a roadmap for leaders seeking to bridge the gap between technological capability and real-world outcomes. Whether you’re a policymaker, provider, technologist, or entrepreneur, there’s a clear message – the future of healthcare lies in building trusted, intelligent, and patient-first systems and the time to act is now. By learning from past efforts and applying the best of today’s technologies, healthcare stakeholders have an opportunity to co-create a future where high-quality care is equitable, accessible, and guided by data we can trust.

Designing AI-Native Healthcare with Innovation, Automation, and Responsible AI.

Season 6: Episode #170

Podcast with Sara Vaezy, Chief Transformation Officer, Providence

Designing AI-Native Healthcare with Innovation, Automation, and Responsible AI.

To receive regular updates 

In this episode, Sara Vaezy, Chief Transformation Officer at Providence, discusses Providence’s strategic approach to digital transformation, consumer engagement, and responsible AI adoption to improve both patient and caregiver experiences. 

Sara highlights the importance of delivering personalized, frictionless, and proactive healthcare experiences across digital touchpoints. At Providence, a standout initiative is the use of conversational AI to enable ‘message deflection’ which reduces the volume of patient messages sent to physicians by helping patients resolve queries instantly through intelligent chatbots. Sara emphasizes building a digital workforce not just to automate routine tasks, but to rethink and redesign workflows creatively. With foundational investments in cloud infrastructure, unified data systems, and interoperability, Providence is well-positioned to scale AI use cases like ambient documentation and care navigation. 

Sara also shares how Providence has incubated and spun off innovative startups like DexCare and Praia Health to address critical gaps in supply-demand matching and patient personalization. She advocates for ethical AI governance, better observability tools, and designing AI-native healthcare processes that go beyond simply replacing human tasks. Take a listen.

Video Podcast and Extracts

About Our Guest

Sara Vaezy serves as chief transformation officer for Providence. She is responsible for leading the Office of Transformation, which is accountable for driving Providence’s responsible adoption of AI to enable the delivery system of the future. Additionally, she oversees marketing, brand, digital — including developing and investing in next-generation innovations and forging partnerships to scale sustainable technology solutions — and virtual care.

Prior to Providence, Sara was at The Chartis Group, advising clients on enterprise strategy, payer-provider partnership, and the development of population health companies. Sara serves as a National Committee for Quality Assurance board director, AARP Services Inc. board director, Praia Health board director, and a board observer for DexCare. She is also a Harvard Executive Education faculty member.

Sara holds dual master’s degrees in health policy and health care administration from the University of Washington and bachelor’s degrees in physics and philosophy from the University of California, Berkeley.


Rohit: Hi Sara. Welcome to the Big Unlock podcast. It is great to have you here. 

Sara: Thank you so much for having me. I’m excited for the conversation. 

Rohit: We are quite looking forward to it. So we will start with some very quick introductions and then dive right into the topic our audience is waiting to hear. I’m Rohit Mahajan. I’m the Managing Partner and CEO at BigRio and Damo Consulting. I will request Ritu to do the intro, and then over to you, Sara.

Ritu: Hi Sara, welcome to our Big Unlock podcast. We are thrilled to have you on the podcast and looking forward to a very insightful and engaging conversation. My name is Ritu Uberoy and I’m the Managing Partner here at BigRio and Damo Consulting, and also serve as the host for the Big Unlock podcast. I’m currently based out of Gurugram, India, and I travel frequently to the US. Really excited to have this conversation because we were in the Bay Area yesterday and every second billboard was an AI billboard—so you know this is what’s happening right now.

Sara: Absolutely. I’m so happy to be here with both of you. Just as a quick introduction for the folks who are listening—I’m Sara Vaezy. I serve as the Chief Transformation Officer at Providence, and I’ve been with Providence for about nine and a half years in total. The transformation role is relatively new for me.

I have dual responsibilities. I have responsibility for the consumer-facing, patient-facing front end for the organization. We serve 5 million patients a year. So how we do our brand, our marketing, our digital consumer experiences to really meet the needs of our communities—ensure that they can find our services, that we can bring them in, that we can retain them—that’s a big part of what we do across channels. Whether it’s web, mobile, proactive outreach, phone—all those types of connected digital experiences.

I also have in parallel this newer responsibility around transformation, which started out as a bit of a nights and weekends project back when GPT became publicly available. I had a feeling there would be a really important impact on our industry and that we needed to lean in. That morphed into a formal role around identifying and being responsible for driving AI adoption—responsible AI adoption—to get maximum value for it in our system. Do so in a way that keeps our patients safe, keeps our caregivers— we call all the folks that work at Providence caregivers—safe.

That’s been the undertaking over the last several months. We’re going to be really focused and drive it across a couple of specific domains. We’re not just going to do it spray and pray, but really focused.

That’s what I’m responsible for. I’ve been in healthcare for a long time. Prior to coming to Providence, I was in management consulting. Before that, I worked in health policy and health services research. I started out my career as a research scientist in med tech. Healthcare is something I love and is very near and dear to me. There are a whole lot of problems for us to solve. So the job is never done—and it’s a lot of fun.

Rohit: Absolutely. The landscape is changing so fast that it’s hard to keep up, but there are a lot of very interesting innovations coming our way.
So how do you think about the consumer-facing apps, and how does it make a big difference to the patient’s experience and care?

Sara: It’s an interesting question, and you’ve separated consumers and patients—we tend to do that as well. Actually, I kind of don’t like the term “consumer” either because it has the implication that you have the means to participate in the market or to buy services. That’s not really what we mean. What we mean is that each person has agency over their own healthcare, their own decisions, and we want to support that.

What we’ve really focused on is a few different things. The first is that we really need to make finding our services and transacting with us—like booking an appointment, paying your bill, getting financial assistance or counseling—a lot easier. Even things like just creating an account. A lot has changed with the electronic medical record companies too, making it easier to create accounts.

But back in the day, you needed a special code, or you needed to have a clinic visit already, and there were just lots of barriers to doing things easily. We’re really removing those barriers as much as we can—making it easy to find what you need, whether it’s a physician, content, or something else. Taking out the friction, making it easier—that’s job one.

We’ve got some pretty lofty goals. Things like online scheduling are still a battle for us. But we aim to make sure anything that is bookable has the option to be booked online. That doesn’t mean everybody will exercise that option, but it means it’s available to them. It’s just like booking a flight or hotel—there shouldn’t be secret sources of data. Everything needs to be available from the same source of truth and be frictionless.

The second piece we’re focused on is that each person is different. If we really want to keep people engaged, we need to recognize how important personalization is. I have a different experience than Rohit, who has a different experience than someone else. We live in different parts of the world. We have different healthcare needs. I have a six-year-old son who is a proxy on my account. All of these things are different. We need to deliver different experiences, and we know that makes a big difference in terms of keeping people engaged.

Rohit: Especially because you said you have 5 million patients that you’re serving. That’s such a large number. There must be so much diversity in that, and it must be spanning many different. 

Sara: Exactly. Many different states. We’re up and down seven states in the Western United States—Washington, Oregon, California, Texas, New Mexico, Montana, and Alaska. Very different states. Some have big urban areas like Los Angeles and Seattle, and some are very rural, like northern Alaska. It’s a very diverse footprint—different types of services, people, and expectations.

The last piece we’re really focused on from a consumer perspective is the expectation piece. We have to engage with folks in the way they’re used to engaging. I know we’ll get to a topic around AI and what we’re seeing there, but conversational platforms are big. People want to do things synchronously but not necessarily get on the phone. Helping them navigate in real life is another big area we’re focused on from a consumer perspective.

So—personalization, frictionless experience, and helping people navigate—those are the big ones. And they apply to everything—from marketing campaigns, to what people see on our web and mobile, to their experience when they call into our contact centers.

Rohit: That’s awesome. And Sara, how do you approach patient engagement and consumer engagement with product development? I know you have a very thoughtful way of doing these things. What’s some of the secret sauce you can share that leads to success in this area? 

Ritu: Yeah and that would be a great lead into like giving us a success story maybe around this topic. 

Sara: Absolutely. I can do that and I’ll give you a story that kind of bridges the gap into the AI work that we’ve been doing as well. The main difference between traditional sort of just how you might turn on features and just try to make an experience ever so slightly better versus a product development approach, which is like think about things end to end.

It’s not just about turning on a feature to be able to book an appointment, for instance. How do you actually even know, like how do you get directed to the right care in the first place as an individual? How do you make sure that care is discoverable, that it’s appropriate, that it really meets a person’s needs based on their intent and motivation and preference and their clinical needs? All of that is its very data driven. It’s very precise, not perfect, but it’s a little bit more precise than just saying, ‘we’re going to slap up an option of booking an appointment.’ Booking an appointment is a feature, a product development approach which is really seeing that whole customer experience end to end.

It supports the experience from discovery through delivery—for instance, the booking experience. We’ve done a lot of product development to facilitate that end-to-end experience. One example—and then we can extrapolate it to a bigger one—is we built a conversation and navigation platform that helps our patients get their needs met without having to message their physician.

That’s an important problem to solve. We have six to seven million patient-generated messages annually that go to our physicians. These go into what’s called the physician’s in-basket, and they have to be managed somehow. That’s a huge volume. So what we said was, let’s take a different approach. Let’s not just ask, “How do we manage the message?”—which is a proximal problem—but go upstream and ask, “Why are patients sending a message in the first place?”

We realized they either can’t find the content they need, or they can’t complete the task they’re trying to complete. For example, with appointment booking or financial counseling, they might not understand their bill or may need help paying. So they end up sending a message.

But what if we could understand what even a complex message is asking, use intent recognition, and then activate agents to fulfill that task? We’ll get to that AI agent world in a moment. But this approach helps patients get their needs met immediately, instead of waiting 24 to 48 hours for a response.

We’ve seen what we call “message deflection” up to 30%, and we’re aiming to deflect approximately 2 million messages annually over the next couple of years. That’s a massive impact on patient experience. And we couldn’t have done it if we just narrowly thought about reducing messages. It’s not just about that—it’s about the full experience. That’s where product development comes in.

Rohit: That’s very cool to know, Sara. Could you tell us a little more—for those in the audience who don’t know—what is “message deflection”? 

Sara: It’s a bit of a challenging concept. We’re using data science methods to say, “This message would have otherwise been sent, but it wasn’t—because the patient got their need met another way.” So we avoided or “deflected” the message.

Simply put, our patients interact with a chatbot. The chatbot walks them through the experience in a natural, conversational way. Instead of sending a message to their physician, they get their need met right then and there. We can understand about 90% of what patients are telling us. We call it “goal conversion”—and we’re able to meet their need 50 to 60% of the time.

Ritu: So you’re freeing up physicians’ inboxes. And like you said, patients don’t have to wait 24–48 hours, which creates frustration for everyone. If the chatbot can understand the intent and serve them right there—that’s a powerful concept. Thank you, Sara.

Rohit: And Sara, you mentioned agents—AI agents. Let’s get to that. We’re talking about a digital workforce transformation as well. What are your thoughts? What are you seeing down the pike? Agents are already becoming mainstream, especially voice agents. You also mentioned domain-specific implementations—what are your thoughts around those?

Sara: On the agent front, things are moving really quickly. If you had asked me this six months ago, I would’ve said, “Yes, agents are going to be very material, and a digital workforce is critical.” I still think that’s true, but we shouldn’t limit ourselves to only taking what humans currently do and asking computers to do it.

That’s not an optimized view of the possibilities. We can be more creative. A digital workforce doesn’t get sick, works 24/7—that’s great. But baked into that assumption is the idea that there’s no redesign of the process—they’re just running the same thing. I think we have to combine agents with actual process redesign.

It’s not just about automating dull or low-value work. It’s about doing things better. We don’t want to just automate bad processes. We want to improve them. That’s what I sometimes struggle with—I want to ensure that, as an industry, we’re reflecting on this deeply. It’s not just substitution—we need to think about it more materially.

Another thing is, there are tasks humans simply can’t do that we should be imagining as algorithm- or computer-powered. For example, when we do a marketing campaign, we look at our footprint and say, “We care for 5 million people, but we’re in communities with tens of millions.”

We can say: based on our data, here are 1,000 individuals who need a specific kind of care. And then we can proactively do outbound outreach and get them in. No human can parse through 10 or 20 million individuals and find the 1,000 who need a particular service. That would take decades.

But we can now do that easily at scale. So when we talk about agents, we shouldn’t limit the conversation to tasks we just don’t want to do anymore—we should be thinking about entirely new possibilities.

Rohit: I see what you mean. Yeah. That’s a very interesting aspect. 

Ritu: Sara you really hit the nail on the head. Rather than just thinking about agents to automate busy work or doing the same things the same way, she’s saying, look at it more holistically and think outside the box—think about new ways of doing things. It’s what we always talk about in our webinars: generative AI is not just about doing the same things better, but looking at things in a whole new way. The technology is so amazing, and with summarization and pattern matching—these are capabilities we just didn’t have before. So, you really need to leverage those to think about new ways to address a problem. That was very insightful. Thank you. 

Rohit: We previously touched upon in the conversation how you’re leveraging a data-driven approach. With such a big health system and so many disparate systems, how did you think about getting this data engineered in a way that would be useful for the applications or products you’re building? Just wanted to go back and talk a little about that interoperability and how you stitch together the diverse systems. What approaches do you take on that side of things?

Sara: This is a credit to our CIOs in the past, in particular. We’ve been on a multi-year journey to get some of our infrastructure in order and do some of the data platform work we needed. Now, we didn’t know that in 2022 we were going to have large language models available to us and go through this big revolution, but we had already done a lot of work getting alignment around our electronic medical record. So, we don’t have ten different systems—we’re on Epic, and there’s a tremendous amount of alignment around that.

The second step is that we’ve been on a cloud migration journey for many years, and we have all of our data in the cloud. We partner with Microsoft and utilize Azure. Cloud computing has unlocked so much of the potential we’re seeing today.

We’ve also spent many years on this data journey. We have an enterprise data warehouse—it’s very sophisticated. There’s been a tremendous amount of data engineering, unification, normalization, standardization, and de-identification to make the data usable for a variety of use cases. That was all thanks to our information services and IT teams over many years.

In parallel, we were doing a lot of the consumer experience and digital work, and these efforts converged over the last couple of years. That’s what’s really accelerated our progress. We were then able to partner with application companies on use cases like ambient assistance for documentation and charting, or in-basket management, which I mentioned earlier. But we could only do all of that because we had already made those multi-year infrastructure and data investments.

Rohit: Right. So, as we’re getting toward the end of the podcast, I’d like to talk about a couple of things—and please feel free to add anything from your side as well. One is innovation and incubation: how do you look at startups that bring value to the table? And could you talk about some successful startups spun out from your organization? 

Sara: I will say that—I’ll preface this—obviously I have a lot of fondness and warmth in my heart for this activity, but it is a very tough thing to do. It’s labor-intensive, it’s resource-intensive. And so a lot of systems don’t do it because they either don’t have the scale or they haven’t built up the capabilities. 

But many years ago, when we were in more stable financial times, we were able to look—and thanks to the foresight that we had—we were able to say, there’s missing technology, missing infrastructure out there that prevents us from successfully, for instance, matching supply to demand for our patients who need care, or delivering a truly personalized experience, because we know our patients and we’re able to create personalized experiences around what we know about them. 

And so, in those two cases, we went really deep into these problem areas. We had a team of folks that could build technology—big startup folks or big tech folks—product managers, engineers, UX, UI, product analytics folks. And we built two companies.

One was called DexCare. We spun that company out in 2021. That’s exactly what they do—they do supply-demand matching for on-demand care. So essentially help folks find the care that they need, make sure it’s discoverable, direct people to the right venue or modality of care, and ensure that there’s capacity. So you’ve got to manage the supply side. DexCare was spun out in 2021, and they’ve been off and running, doing amazing work.

We also spun out a company last year in 2024 called Praia Health. Praia is focused on personalization and driving engagement through knowing an individual and giving them exactly what they need—what’s relevant to them—as opposed to a more vanilla or generic approach.

So we built those two companies. They’ve raised venture capital in the tens of millions of dollars, and we continue to utilize them to power our consumer experiences in the system.

Rohit: That’s great. Sara, would you like to talk a little bit about what you see in the future—maybe over the next year or two? Things are changing fast, but what are some of your thoughts about generative AI, LLMs, and GenTech AI? How should one approach it? 

Sara: You know, if I knew that part, I’d probably put more money into the stock market—or any money into the stock market. Of course, I don’t. I’m very wary, especially with how quickly things are moving. But I think there will need to be some breakthroughs in the not-too-distant future, more focused on the energy that’s needed to power these sophisticated and energy-hungry models.

We’ll get more efficient, but we still have to solve some fundamental energy problems. That’s a big focus area—because without that, we can’t push innovation much further. There’s just too much GPU consumption.

Another thing I think we’ll see more of in the next couple of years, on the core AI software side, is a normalization. Right now, there are tons of little solutions out there, and some are getting massive valuations for unclear reasons. I think we’ll start seeing more focus on wholesale redesign—of business processes, data needs, operational needs—not just tech for tech’s sake. More AI-native thinking, not just substitution.

I’m especially curious to see what happens in the ambient assistant space. Some of those companies are at huge valuations, and I think a lot is going to change for them in the near term.

I’m also really excited about the monitoring and observability space—how we know what’s going on with these models. Before deploying, you have to test and validate, of course. But in runtime too—if you’re using an unsupervised, non-deterministic model, you better have a system to ensure it doesn’t go rogue. I think we’ll see advancements there.

And I’m very interested in the new workflow automation tools. I think the toolsets themselves will get better, allowing people to build the use cases they want more easily. That’s something I’m excited about.

Ritu: I just wanted to ask a last question, which was more like on the philosophical side. Because just a year ago when we were doing our webinars, we were talking about human in the loop. You know, AI is here to augment, not automate, and within a year we’ve gone, full 180 and now we are saying that it’s agents, it’s going to be totally autonomous. They’re going to be doing things on their own. So, like you said about rogue agents or shadow agents, how do you feel about seeding that kind of control to energetic workforce, which humans may not be completely in control of. 

Sara: Frankly, I think it is almost like fighting gravity and our job is to make it as responsible and humane and ethical as possible. I’ll give you another example, which is like, folks often used to say, back before we got really comfortable with sharing our own personal data all the time, folks would say things like, “I think that each individual needs to own their own data.’

That’s like a fine statement in a way, but it’s like a very facile statement. What does that actually mean? And like when you actually get into it, nobody owns their own data. Companies own your data and they do stuff with it and you have agreed that it’s okay, you know? I think we actually missed the mark on doing it humanely and ethically and with integrity and in this case, let’s not miss that Mark and say, ‘we know it’s going to happen, that we’re going to have huge displacement, huge amount of like change economically from a workforce standpoint, from an experience standpoint. It’s going to happen. How do we do it right?

Rohit: Thank you, Sara. This has been a great interaction. We really appreciate you being our guest on the podcast. And I hope the audience will like it as well, so thank you.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.



About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Scaling AI in Healthcare: Insights from Dr. Alvin Liu on Real-World Implementation and Governance

Scaling AI in Healthcare: Insights from Dr. Alvin Liu on Real-World Implementation and Governance

In a recent episode of The Big Unlock podcast, Dr. T.Y. Alvin Liu, Inaugural Director of the James P. Gills Jr. and Heather Gills AI Innovation Center at Johns Hopkins Medicine, shares his journey into artificial intelligence and how his work is transforming healthcare delivery. As a practicing retinal surgeon and AI governance leader, Dr. Liu offers a unique perspective at the intersection of clinical care, innovation, and enterprise AI strategy. His conversation with host Rohit Mahajan spans several key themes—from deploying autonomous AI for diabetic retinopathy screening to scaling generative AI for operational efficiency and building a robust AI governance framework for health systems.

From Ophthalmology to AI Leadership

Dr. Liu’s foray into AI began in the late 2010s during his clinical training, sparked by groundbreaking studies—particularly one from Google—that demonstrated the ability of AI models to predict cardiovascular risk factors from retinal images. This superhuman diagnostic capability was a turning point for him. As a retina specialist immersed in an image-rich field, Dr. Liu recognized the untapped potential of deep learning to transform how clinicians interpret complex visual data.

At Johns Hopkins, Dr. Liu leads the Gills AI Center—the first endowed AI initiative at the Johns Hopkins School of Medicine—while also maintaining an active clinical practice. He contributes across four pillars: AI development, implementation, governance, and scientific innovation, giving him a panoramic view of the opportunities and challenges in healthcare AI.

Autonomous AI in Primary Care: A Case Study in Diabetic Retinopathy Screening

One of the most compelling examples Dr. Liu shared was the deployment of an FDA-approved autonomous AI system to detect diabetic retinopathy in primary care settings. This system was the first of its kind to be approved for autonomous clinical use, and Johns Hopkins began implementing it in 2020.

Traditionally, patients needed to see a separate specialist to complete an annual retinal screening—an extra step that often led to missed appointments and lower screening rates. The AI system allows primary care physicians to take retinal images in their office, with AI analyzing them in real time. Patients receive immediate results, and only those with positive screenings are referred to an ophthalmologist.

The outcomes have been striking. Johns Hopkins observed a marked improvement in screening adherence, especially among underserved populations such as African Americans and Medicaid recipients. These results, published in Nature Digital Medicine, underscore how AI can help close gaps in preventive care—if implemented thoughtfully.

Generative AI for Revenue Cycle: From Clinical to Operational AI

AI’s impact at Johns Hopkins isn’t limited to the clinic. Dr. Liu described a pilot project using generative AI for revenue cycle management, specifically prior authorization. This is a high-friction area in healthcare, involving extensive paperwork and delays in care.

By leveraging large language models (LLMs), Johns Hopkins automated prior authorization workflows, reducing the time required and handling unstructured data far more effectively than traditional robotic process automation (RPA) methods. These results illustrate how AI can unlock value beyond clinical domains by streamlining healthcare operations and improving provider efficiency.

Startups and the Reality of Healthcare AI

Drawing from his experience working with numerous startups, Dr. Liu offered candid advice to AI entrepreneurs: understand reimbursement from day one. “I think one of the common mistakes that startup companies make in the healthcare AI space is not considering or not understanding their reimbursement issue from day one,” Dr. Liu added. Many startups make the mistake of focusing on building a great product without planning for how it will be paid for—especially in a field as complex and regulated as healthcare. 

He emphasized that FDA approval alone isn’t enough. Startups must also determine whether existing CPT codes apply to their solution, and if not, navigate the lengthy and uncertain process of obtaining new ones. Beyond regulatory hurdles, they must build business models that reflect the real-world economics of health systems.

Startups often underestimate the cost of this journey—$3 to $5 million for FDA approval is typical—and many don’t budget appropriately. Dr. Liu’s message was clear: clinical AI solutions need sound financial strategies as much as innovative technology.

Creating Enterprise-Ready AI: The Johns Hopkins Governance Model

To manage the influx of AI tools and ensure responsible adoption, Johns Hopkins established a robust AI governance framework. Dr. Liu is part of an eight-member enterprise leadership team that evaluates all AI-related initiatives across the health system.

This governance model is built around seven core principles: fairness, transparency, accountability, ethical data use, safety, evidence-based effectiveness, and sustainability. Any AI vendor seeking to partner with Johns Hopkins must complete a standardized intake process, provide detailed documentation on their tool’s safety, ROI, and evidence base, and undergo a rigorous review process.

The system categorizes tools based on their use case—clinical, operational, or imaging—and advances each proposal through specialized review committees. This ensures that tools align with Johns Hopkins’ mission, technical infrastructure, and patient care goals before they are deployed at scale.

This governance model could serve as a blueprint for other integrated health systems navigating a crowded and often chaotic AI vendor landscape.

Looking Ahead: Omics, Risk Prediction, and Scaling Innovation

Dr. Liu also shared his excitement about the emerging field of AI-driven “omics,” particularly using retinal biomarkers to predict systemic health conditions such as cardiovascular disease, kidney damage, and dementia. AI-enabled retinal screening programs in community settings could identify at-risk individuals years before symptoms emerge.

However, he was quick to point out that identifying risk is only part of the equation. Health systems must also build the care pathways to ensure those flagged by AI are connected to the appropriate subspecialists and receive timely follow-up care. Without that, the potential of predictive AI will remain unrealized.

A Call for Collaboration: Startups, VCs, and Health Systems

In his closing remarks, Dr. Liu highlighted a growing but still insufficient level of collaboration between AI startups, venture capitalists, and integrated health systems. Startups drive innovation and speed—but they often lack the domain knowledge and infrastructure to scale safely. Health systems, on the other hand, deliver the majority of care but tend to move slowly due to regulatory and operational constraints.

Bridging this gap, he argued, is essential for sustainable AI deployment. Startups need to understand the realities of clinical practice and reimbursement. Health systems need to improve agility and decision-making. And investors need to align their expectations with the long, complex arc of healthcare innovation.

Dr. Liu hopes to see more structured partnerships where these groups work together to solve real problems, share risk, and scale proven solutions responsibly. He believes that such collaboration is essential for delivering long-term value—and ultimately, for improving health outcomes.

AI is Here to Stay

As Dr. Liu puts it, “The train has left the station.” AI is already reshaping healthcare, and the focus must now shift to responsible scaling, thoughtful implementation, and real-world results.I think the vast majority of people will agree that AI will change medicine and society as we know it,” he adds. 

Whether through autonomous diagnostic tools, generative AI for operational efficiency, or predictive omics models, the future of healthcare will be defined by our ability to integrate AI into the fabric of care—ethically, equitably, and effectively.

This episode is a powerful reminder of what it really takes to turn promising AI into real-world results. For health systems, startups, and investors, Dr. Liu’s insights highlight why successful innovation depends as much on execution as on technology.

Advancing Pulmonology with AI and Functional Imaging

Season 6: Episode #169

Podcast with Vishisht Mehta MD, FCCP
Director, Interventional Pulmonology Comprehensive Cancer Centers of Nevada Department Chairman, Pulmonology
MountainView Hospital

Advancing Pulmonology with AI and Functional Imaging

To receive regular updates 

In this episode, Dr. Vishisht Mehta, Director of Interventional Pulmonology, Comprehensive Cancer Centers of Nevada and also the Department Chair of Pulmonology at MountainView Hospital, discusses his passion for clinical practice and emerging technologies like AI and telemedicine. 

Dr. Mehta shares how his interest in AI began through vendor outreach and evolved into a deeper exploration of its applications in pulmonology, particularly in early lung cancer detection and functional imaging. He highlights the persistent underutilization of lung cancer screenings, with only 5–6% of eligible patients getting screened, and notes AI’s role in identifying high-risk individuals and managing lung nodules. He also emphasizes the value of telemedicine in improving patient access and outcomes. 

Dr. Mehta has also created a resource hub – https://pulmonary.ai/ and produced educational videos to guide clinicians in understanding and adopting AI tools. He advises that physicians must gain foundational AI literacy to make informed technology decisions in an increasingly digital healthcare landscape. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Dr. Vishisht Mehta, is the Director of Interventional Pulmonology at the Lung Center of Nevada, a division of Comprehensive Cancer Centers and also the Department Chair of Pulmonology at MountainView Hospital, both in Las Vegas. He is a Clinical Assistant Professor at the Kirk Kerkorian School of Medicine in Las Vegas, NV. He is fellowship trained in Interventional Pulmonology, which specializes in the minimally invasive diagnosis and treatment of lung conditions.

Dr. Mehta has authored and reviewed various scholarly articles. At international conferences, he has been a presenter and moderator for numerous sessions. He has also received awards and grants for his research endeavors. He is a recipient of the prestigious Fellow of the College of Chest Physicians designation from CHEST (American College of Chest Physicians), is a Diplomate of the American Association of Bronchology & Interventional Pulmonology, Fellow of the American Thoracic Society, serves on the Nevada Leadership Board of the American Lung Association and the Executive Board of the Nevada Cancer Coalition and the American Lung Association’s Nevada chapter. He is also the Founder of the Nevada Lung Foundation and Pulmonary.ai, both of which are his personal projects to improve lung health and AI education respectively. He has been recognized by Vegas Inc. with its prestigious “40 Under 40” award in 2023.

His additional expertise lies in the application of artificial intelligence in pulmonology, especially in the early detection of lung cancer. He has been invited to speak on his expertise in AI in pulmonology at local, national and international meetings and events.

Dr. Mehta attended the Rajiv Gandhi Medical College and Chhatrapati Shivaji Maharaj Hospital in India, receiving a Bachelor of Medicine, Bachelor of Surgery degree in 2012. He completed a residency in Internal Medicine at the Creighton University School of Medicine in Omaha. He later completed fellowships in pulmonary and critical care at Memorial Sloan Kettering Cancer Center in New York City, and an Interventional Pulmonary fellowship at Henry Ford Hospital in Detroit.


Q: Hi Vishisht. Welcome to The Big Unlock podcast. Very happy to host you. You’re joining us from Nevada, and it’s such a fun place. I was recently there at HIMSS, and we got to chat a bit. I’m Rohit Mahajan, Managing Partner and CEO at Damo Consulting and BigRio, and the host of this podcast. Would you like to start with an introduction? 

Vishisht: Absolutely. Thanks for having me. It’s good to reconnect after our initial call.
My name is Vishisht Mehta. I’m an interventional pulmonologist based in Las Vegas, Nevada. I’m the Director of Interventional Pulmonary at Comprehensive Cancer Centers of Nevada, a community practice with a large oncology presence. My colleagues and I are the lung specialists within the organization. We see a wide range of conditions—COPD, asthma, lung cancer, infections, lung scarring, interstitial lung disease, and more.

I trained in New York City, and working in Las Vegas has been a very different professional environment. Since starting practice, I’ve become increasingly involved in digital health, pulmonology, and emerging technologies. It’s been very interesting to be part of that space.

Q: Yeah, of course. So Vishisht, tell us a little bit about when and how you got attracted to the tech side of things. I guess you still practice even today, right? So a large amount of your time is spent seeing patients, but on the other hand, you have this strong interest in new technologies and AI, which we’re going to talk about. So how did you get involved with that?

Vishisht: So as far as the AI thing, it started because one of the vendors reached out to kind of just talk about their product, and I found that technology interesting. This is about three, four years ago now, but it did not seem ready for prime time. The concept was definitely intriguing.

So I tried to educate myself more about: What is AI? Is AI here yet in medicine and pulmonology? Is this something that will be technically successful but may or may not actually do anything for my patients? And then, all different AI technologies are different. Even though they may look somewhat similar, some of it is patient-facing, some of it is not.

So that’s kind of how I got involved from the AI perspective. And then COVID happened, and we started doing a lot of telemedicine. So that was another exposure to digital aspects of medicine.

There are other technologies emerging, for example, functional imaging in lung diseases. Most of the normal imaging we do is static—as in, a patient takes a breath, holds the breath, and we take a picture—chest x-ray or CAT scan.

But functional imaging is new and emerging now, where we are able to see how different phases of breathing affect someone’s lung. That’s information we did not have.

So I try to expose myself to these things because we just need to know. And it’s also very interesting. This is very nascent. I’m early in my career. These technologies are early in their deployment, development, and adoption. So it’s something I think will be a part of medicine going forward—and a big part of how I’ll be involved in medicine. So that’s kind of the background.

Q: That’s very interesting—how you segued into AI and technology. You talked about telemedicine as well. Just curious to know, on the telemedicine side of things—obviously the number of visits has dropped—but are you still seeing a mix, Vishisht?

Vishisht: Definitely. Telemedicine is here to stay, and our patients like it. We like it. It works very well for the right scenario. Sometimes if a patient is coming back to follow up on some imaging or blood test, they don’t necessarily need to be in the office. We don’t need to be sitting across from each other. We can do it just like how we’re doing now—have a conversation, look at labs, blood work, images, and make a decision.

I’ve had patients do telemedicine appointments from the park, the playground, from home. A few have done it at the airport. Routinely, people do it during lunch breaks or at work. Now they don’t have to miss work. They don’t need someone to drive them. There’s so much time saved.

Because it’s easy, you can have visits more frequently. I’ve had patients with bad flare-ups of COPD or asthma. We do a telemedicine visit, I prescribe what they need, and they avoid going to the hospital. They don’t have to come in. If they have an infection, others aren’t exposed. So our patients are also safe. It just works. As a concept, I think it’s very useful, helpful, and definitely here to stay.

Q: That’s amazing. The other thing I wanted to ask is something you mentioned—functional medicine or functional imaging. Could you talk about that? Are the machines different and new? That must mean more data, right? How does that work? 

Vishisht: Functional imaging is very interesting. There are different parts to it. For example, we do a test called pulmonary function test—typically called a breathing test. A patient sits in a transparent box. The box is closed because we need to control the environment. They get coached and do a series of breathing maneuvers—deep breath in, deep breath out, blow hard, breathe normally.

These tests assess how the lungs are functioning. We can see if someone has asthma, COPD. We can measure lung size and the ability to extract oxygen. That’s very helpful information—but there are no pictures involved.

Also, for each outcome, we get a composite answer for both lungs combined. But that assumes the condition affects all parts of the lungs equally, which is not always true. Some patients have emphysema more in the upper lungs, or conditions that affect the edges or bottom parts.

These tests can’t tell that. The hope with functional imaging is that we’ll be able to image the lungs entirely and see if different areas function differently. That’s very promising and may change how we understand lung conditions.

You asked about hardware. Some technologies, like scanners using hyperpolarized xenon gas, do require additional hardware, capital investment, and training. But other imaging technologies use existing scans with different protocols. For example, we might do a scan after a deep breath in, then after a breath out, and compare.

So for those, we already have the technology—we just need different protocols and people who can interpret the results. The scan machine is the same; the protocol and interpretation differ. The leap to get there is small. These are just some examples of where things are going. I believe it will move in that direction, but we’ll have to see. It’s exciting to have new tools to offer our patients.

Q: Right. And let’s talk about AI. You mentioned it a couple of times. What kind of AI is applicable in your area of practice? What are you seeing?

Vishisht: AI in medicine—and in pulmonology—we’re seeing it show up in different areas. Most prominently, we’re seeing it in lung cancer. A lot of it is focused on early detection of lung cancer, or identifying spots or nodules on the lungs.

We know lung cancer is the most lethal cancer. But if caught early, survival is much better. In some cases, we’re talking about cure—not just management. So we want to screen high-risk patients.

AI helps by identifying high-risk patients, currently by looking at smoking history and pulling that information from the chart. It flags those patients for lung cancer screening discussions.

Another area is incidental findings. A patient might get a CT scan of the abdomen, and a small lung spot is seen in the lower lung—even though the scan wasn’t done for that reason. Same with scans of the neck or thyroid—you might see part of the upper lung.

AI software can identify these nodules, whether in the report or image, and generate a list for the hospital or doctors. It flags them so we can follow up and determine if they’re important.

We’re also seeing AI used to judge the risk of cancer in these spots. Many people have lung nodules, most of which are not concerning. But AI can analyze data we can’t see with our eyes—data that’s in the scan—and help us assess whether a spot is likely cancerous.

It’s not diagnosing cancer yet, but it helps assess risk. So that’s where we’re seeing AI most—in early detection and identification of nodules.

Q: That’s great. You mentioned lung cancer screening—I have a curious question. In your health system or nationwide, since you’re connected with physicians elsewhere, what is the current percentage of eligible people who actually get screened? Is there a gap? 

Vishisht: There is a massive gap. It’s probably the biggest gap between eligibility and screening for any cancer. Ballpark, we’re screening about 5–6% of eligible patients. That’s a huge miss compared to other cancers like colon or breast, where screening is around 70–80%. 

Q: Any thoughts on why that gap is smaller for those cancers and bigger here?

Vishisht: Yeah, you know, at some level, lung cancer screening recommendations have been out for a while, but for whatever reason, they seem to not have percolated as much. I think the true number of patients who get lung scans is probably a little higher than this because patients may be getting scans for reasons other than screening, which maybe are not being tracked. But there’s no doubt that the gap is there.

I think there’s a lot of stigma also. Because lung cancer, because of the association with smoking, has some amount of blame attached to it, unfortunately. We should not be blaming patients, certainly not for actions in the past. And if someone is eligible, we should have the discussion with them.

One of the things to think about, if you think about AI in this space, is AI is doing a lot of interesting things when we find the lung spot. But what about finding the patients who need to be screened? I think that’s another place where AI is going to help us.

And I will also say we have to keep in mind that maybe the answer is not AI to improve lung cancer screening. Maybe we just need resources, education, manpower. That’s another long discussion. But we should not be thinking that AI is going to fix it, and it could be many things that are likely to help move the deal.

Q: That brings me to the point we were talking about a little earlier—that you actually have a website and a video that you’ve put up for people to learn more about this. You mentioned pulmonary.ai. Also a video on YouTube, right? So would you like to tell us a little bit more about that?

Vishisht: Yeah, for sure. Again, like two-ish, maybe three years ago, when I was trying to get more details and get more involved, I said, let me go and find AI and pulmonology resources. So I went online and I went looking and looking and looking, and I could not find anything where all the stuff that I was interested in was in one place.

I had to go and pull this article from here, that article from there, this clip from here, to try and educate myself. And then I said, why don’t I try and make the place where I can post some of these articles? It’s not going to be everything—because it’s impossible to keep up. One-man army, sort of.

But to my surprise, pulmonary.ai, the domain was available, so I took it. And I have been trying to add different pieces of pulmonary and AI literature, research articles in different areas, so other people who are interested in this subject, like I am, don’t have to run around as much. At least they can go to this website and have a good start.

This is not meant to be exhaustive and cover every possible thing—again, it’s not possible. But at least as a starting point, they can go on the website. I maintain it myself. There’s no commercial, no ad, no sponsor. I pay for it myself. It’s just my personal hobby and effort to find like-minded people.

That effort helped me generate my first large lecture on this, which was AI in Pulmonary Nodule Management. I went on YouTube, I did that for the Society for Advanced Bronchoscopy, a wonderful medical society that I’m a part of. And a year later, the follow-up lecture, which is the one you’re referring to, was Which AI Should I Buy?

Because after the first one, we started to see so many different vendors show up in this lung nodule space. And the question that I kept getting asked was, “Okay, that’s fine. Which one?” And not only which one, but “How do I decide which one?”

So that led to the second one, Which AI Do I Buy? And that’s, of course, a very important discussion. Sometimes people ask, “Do I definitely need AI?” And right now, I’m saying—I don’t know if everyone definitely needs it, but I think the conversation should definitely be had.

Because there are many challenges—cost, integration, reimbursement. The other challenges are the physicians, administrators, or nurse navigators—do they know how to use the software? Do they understand the pros and cons?

We do not want to have a problem of round peg, square hole—trying to fit things where they’re not supposed to fit. That’s mostly what I speak about—how rather than what. Because it’s not for me to tell any one person this is better or that is better.

Q: So, what’s one or two nuggets from the Which AI Should I Buy? video that you’d like to share here?

Vishisht: That’s a very hard question. I think one thing that’s important, and I’ve realized this over time, is that physicians, administrators—whoever is interacting with the software or making purchasing decisions—need to have a basic level of understanding of what they’re interacting with.

Even when we routinely read research articles, we’ve not—and for obvious reasons, because AI wasn’t there—we’ve not been familiar with the terms needed to judge AI literature. So when you look at an AI paper, you have to look at or be familiar with terms like structured/unstructured data, unsupervised learning, what was the development, what was the deployment, internal validation, external validation.

So I think one takeaway would be to familiarize yourself with those kinds of things. Where can you go? Shameless plug—my lecture is one place someone can start, but that’s not the be-all and end-all. There are resources online. Some medical societies have material. MIT has a course on this—I’ve taken it. I think it’s a very good course. Stanford has one through Coursera. There are places where we should go.

So I guess the one takeaway would be—if people are considering these technologies, then just understand how they are different, so the right people can make the right decision for the right circumstance, if it is going to be some AI technology.

Q: That’s awesome. I think we’re almost coming to the end of the podcast today. I’m hoping we’ll have more conversations in the future. 

Vishisht: I appreciate the opportunity to talk to you and your audience. In closing, all I’d say is that healthcare is evolving, changing—probably faster in the digital space than we’ve seen before.

So I’d want my colleagues to go out there, educate themselves, listen to lectures, and follow folks like yourself. A lot of the new information may not come from traditional medical societies—just because of the speed. Things change faster than we’re used to.

And at the end of the day, being well-informed, as much as possible, is important with these newer developments. So that’s all I got. Thank you.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected]  

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Reimagining Healthcare From Meaningful Use of Data to AI-Driven Equity

Season 6: Episode #168

Podcast with Aneesh Chopra, Chief Strategy Officer, Arcadia

Reimagining Healthcare From Meaningful Use of Data to AI-Driven Equity

To receive regular updates 

In this episode, Aneesh Chopra, Chief Strategy Officer at Arcadia shares a bold vision for advancing healthcare equity through smarter data use, AI, and workflow innovation. He unpacks the journey from the early days of “meaningful use” to today’s AI-powered, value-based care landscape, highlighting how intelligent workflows can reach underserved populations and improve outcomes at scale.

Aneesh introduces the concept of a “healthcare information fiduciary,” a model where apps and platforms act solely in the patient’s best interest, free from institutional financial incentives. He discusses how this, combined with emerging AI capabilities and interoperability standards like CMS’s FHIR APIs, can empower consumers and scale high-impact care delivery.

With real-world success stories, from improved hospital ratings via conversational AI to national gains in ADT data coverage, this episode offers healthcare leaders a roadmap for driving innovation through public-private collaboration and patient-centered data strategy. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Aneesh Chopra is the Chief Strategy Officer at Arcadia, a healthcare data platform company, where he advocates for interoperability and data-driven approaches that help providers, payers, and employers make smarter decisions to succeed in the shift to value-based care.

Chopra’s influence and leadership in technology includes extensive experience in the public sector. He served as the first U.S. Chief Technology Officer under the Obama Administration, where he spearheaded initiatives to modernize the nation’s healthcare system using electronic health records and health information exchanges. Chopra also served as Virginia’s Secretary of Technology under Governor Tim Kaine.

As a public servant, Aneesh fostered better public-private collaboration, a theme central to his 2014 book, “Innovative State: How New Technologies Can Transform Government.” Chopra’s significant contributions to the fields of technology and healthcare have cemented his reputation as a forward-thinking leader committed to leveraging technology for the public good.

Chopra serves on the U.S. Department of Commerce’s National AI Advisory Committee. He also serves on the boards of Trimedx, IntegraConnect, Virginia Center for Health Innovation, and the George Mason Innovation Advisory Council. He earned his master’s degree in public policy from Harvard Kennedy School and holds a bachelor’s degree in health policy from Johns Hopkins University.


Q. Hi Aneesh, welcome to The Big Unlock podcast. Very happy to have you here. I’ll do a quick intro and hand it back to you. I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting. It’s great to know that you’re already familiar with Damo from your previous interactions with Paddy. We’re continuing to build on The Big Unlock podcast that he started. We’re now in Season 6, so welcome, and over to you.

Aneesh: Thank you, Rohit. I’ll begin by saying how grateful I am that you’ve picked up the baton. Paddy was a larger-than-life individual with had a lot of fans, myself included. I’m grateful you’ve continued this.

By way of background, I’m Aneesh Chopra, currently Chief Strategy Officer at Arcadia. We’re a market leader in putting healthcare data to work in value-based care for payers and providers, with a focus on helping individuals get the best possible care at every step of their journey.

Personally, I’m passionate about improving collaboration between the public and private sectors. I served in the Obama administration as the first U.S. Chief Technology Officer—a position that has thankfully remained bipartisan. I’m grateful for the opportunity to demonstrate what’s possible when we apply technology, data, and innovation to some of the country’s biggest challenges.

Q. That’s great to know. Could you tell us what first attracted you to healthcare?

Aneesh: Like many things, it was about timing. I was an undergraduate at Johns Hopkins in the early ’90s when President Bill Clinton brought national attention to healthcare reform. I had the opportunity to get involved—first as a student, and then as an intern for a Maryland initiative aligned with what Clinton was advocating, led by the university’s president.

That experience gave me an insider’s view of what it could look like to shape the future of healthcare. I’ve always believed that the best outcomes come from collaboration between the public and private sectors. Healthcare, in particular, is one of the defining challenges of our generation.

Back then, I was passionate about the role of internet technologies in democratizing healthcare. Today, I feel even more energized about the potential of AI to do the same—lowering costs and improving outcomes for everyone.

Q. Absolutely. That’s great to know, Aneesh. That brings me to the comment we were discussing before the podcast—about making use meaningful again. That’s a great catchphrase. Can you explain your thought process behind it and what it means to health systems, patients, and the larger population?

Aneesh: Thank you so much. By way of background, your audience likely remembers the term meaningful use—two words Congress wrote into the HITECH Act that led us on the journey of accelerating health IT adoption starting around 2010 when subsidies kicked in.

There’s always been a trade-off. What does meaningful use really mean? If you go to Best Buy and purchase software like TurboTax, you expect it to help you file taxes. But in healthcare, just installing software doesn’t guarantee better patient care. It may only serve the back office for billing or administration, without clinical benefit.

So, Congress allowed us to define what it means to be a meaningful user. That sparked debate. Should we focus on maximizing productivity in a fee-for-service model—like seeing twice as many patients a day—or should we focus on outcomes?

In the Obama transition team, our vision was to shift toward outcome-based models that reward better care. If we fix how people get paid, and incentivize longitudinal care, then technology becomes essential—not just during visits, but also between them. It can remind us of care gaps or flag things like unfilled prescriptions that signal problems with adherence.

So, meaningful use for organizations focused on long-term outcomes differs from those operating under fee-for-service. Our original intent was to prepare for the future—“where the puck is heading,” to quote Gretzky. But the industry found that difficult. We ended up with a half-measured IT program—subsidizing tech mostly built for fee-for-service, with only partial support for value-based care.

Now, the Trump administration’s CMS-ONC RFI is a chance to finish what we started in 2009-2010.

Q. The RFI you’re referring to is the CMS-ONC RFI, right? Can you explain what this RFI is for those who may not be familiar? 

Aneesh: It’s a great opportunity for the private sector, nonprofits, providers, and plans to come together and say: here’s how we want healthcare IT to operate, how information should flow, how patients should access their data, and how clinicians and health plans can coordinate care to improve quality.

It’s an open invitation—across a dozen or more specific use cases—to help define the future we didn’t quite finish under meaningful use. It asks each stakeholder: What do you need? What do consumers want? How can physicians interact with data in real time? Historically, health plans were kept out of public health information networks—so how do we bring them in, and when?

It’s a short 30-day comment period. By the time this airs, it may be over—but that’s not the end. The executive branch will likely take action over the next year. I hope early adopters raise their hands and participate voluntarily before any formal regulation. That’s always been a hallmark of my work in government, and I’m grateful that the Trump administration carried that idea forward.

Q. That’s great to know, Aneesh. Thank you for sharing that. Based on your experience with the Obama administration or your current role, are there any success stories involving AI or interoperability that you’d like to share? 

Aneesh: Yes. We’re grateful to support over 150 health systems, health plans, and ACO networks. We serve as their core data platform to build the longitudinal patient record. The great news is, once you’ve done that work, you can apply use cases on that foundation to help people be more successful.

There are three areas some of our customers have been advancing. The most exciting is conversational AI. One challenge in population management is taking responsibility for individuals who may not come into your clinic regularly. You need to reach out—remind them to get flu vaccines, check blood pressure, manage diabetes.

One academic medical center, mostly a fee-for-service organization, had underperformed on longitudinal measures. They were scoring one or two stars in the Medicare Advantage program, where four stars or more are needed to earn incentives. Their enablement partner—our customer—brought in a conversational AI workflow. It used the physician’s office phone line, declared the automated agent was calling on behalf of their doctor, and helped close hundreds, if not thousands, of care gaps over a 90-day sprint. As a result, they went from a one or two star rating to a four-star rating across several MA contracts—earning over $6 million in bonuses they previously hadn’t qualified for. That’s an example of the co-pilot concept in care management.

Another use case is evidence-based medicine. There’s debate around health plans denying care via prior authorizations. But if you frame it as evidence-based decision support, it becomes more of a nudge. One of our large academic centers, with a library of approved guidelines, has started piloting an AI co-pilot to monitor whether the patient in front of the doctor is a good candidate for a certain treatment. This reduces the cognitive load on physicians and integrates reminders at the point of care. It’s promising.

Finally, interoperability. CMS rolled out a daily FHIR API for health networks in the ACO REACH program. It moved claims data from being available 60 days after service—useful mainly for actuaries—to more real-time use for care managers. One of our advanced primary care clients, focused on high-need senior populations, saw their ADT (admission-discharge-transfer) data coverage improve from about 40% to nearly real-time. It may not be real-time for every patient, but it’s now fast enough to take meaningful clinical action for many more patients.

Q. That’s great to know. And now, thinking a little bit into the future—before the podcast, we were talking about the idea behind healthcare information fiduciary. Could you explain more about your thoughts on that and where this concept might go? 

Aneesh: Yes. A little bit of history first. In the Obama administration, we proposed a fiduciary rule through the Department of Labor for self-insured employers managing 401(k) plans. At the time, there wasn’t much transparency. Many firms were charging 8–10% in fees, when it should have been less than 1%. That became a massive cost to employees’ retirement savings over time—estimated at nearly $3 trillion.

More importantly, brokers had incentives to sell products that paid them higher commissions, rather than products that met the individual’s risk profile or goals. So we proposed a fiduciary rule: if you trust me with your information in a complex domain like financial services, I must act in your best interest—not based on how I get paid.

That standard inspired me to carry the concept into healthcare. As we build health data hubs and consumers gain the right to control access to their information—or request and keep copies—we need to create a marketplace of apps that people can trust. These apps might use AI or other tools to help consumers not only aggregate records, but make better decisions at every step of the healthcare journey.

The key is that these apps must act in the patient’s best interest—not in the interest of a health plan pushing for lower-cost care, a hospital steering to more expensive services, or a pharma company promoting a branded drug when a generic might be better. So a healthcare information fiduciary is both a technical and ethical standard. It’s about creating a trusted ecosystem that organizes and activates personal health data responsibly, for the consumer’s benefit.

Q. Is this something already concrete and coming down the pike, or is it still just an idea? 

Aneesh: It’s a bit of both. I’m one of the co-founders of the CARIN Alliance—a bipartisan effort with Governor Mike Leavitt, Dr. David Blumenthal, and the original National Coordinator, Dr. David Brailer. The four of us conceived a program now led by Ryan Howells to create a category of consumer-facing apps that follow a voluntary code of conduct.

This code addresses one part of being a fiduciary: transparency in how my data is used so I can trust the app. It goes beyond HIPAA, requiring disclosure of even de-identified data use—something hospitals and insurance companies don’t typically do. So the CARIN code of conduct is a step toward a full healthcare fiduciary model, but we’re not there yet.

Combine that with data-sharing rights and an upcoming AI code of conduct, and we may soon see apps that say: “Share your lab results, and I’ll give you next steps”—as we’ve already seen with GPT-like tools.

Q. That’s great. Before we wrap up, I’d love to hear more about your book The Innovative State. It’s been a while since it was published, what lessons remain relevant today? 

Aneesh: I appreciate that. I was inspired by Sam Pitroda. Back in the ’80s, India had just 300,000 phone lines for 300 million people. Sam, after selling a business, returned to India with a symbolic salary and a bold goal: connect every remote village. He rejected both the public subsidy model and deregulation-only approach. Instead, he chose a third way: innovation.

He recruited hundreds of brilliant minds and built a digital-first telecom network. Within a decade, villages had STD booths and modern phone access.

That inspired my approach to public sector innovation—looking for that hidden “third way.” The heart of my book focuses on strategies that empower both government and private actors through handshakes and handoffs.

Innovation is often bipartisan. Washington can create the pathway, but it’s the private and nonprofit sectors that must execute. That includes opening government data, setting interoperability standards, introducing outcomes-based payments, and recruiting talent for “tours of duty” in government. These ideas are still highly relevant today.

Q. Absolutely. So. as we end the podcast, Aneesh, any parting thoughts or any final words for the audience that you would like to share? 

Aneesh: Yes. In the spirit of the conversations Patty used to lead—this is our moment to raise our hands. If you see the future and want to help build it, now’s the time. The Trump administration’s RFI will kick off a series of actions this summer, fall, and maybe winter.

If you’re ready to be an early adopter, we want to hear from you. Reach out to me or connect with Washington. Let’s organize the early adopters, test what works, and then scale it across the sector.

Q. Amazing. Thank you, Aneesh. This was a great conversation. Hope to have you back again soon. 

Aneesh: Thank you, Rohit. Appreciate you having me. 

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Most Frequently Discussed Themes on The Big Unlock Podcast

Most Frequently Discussed Themes on The Big Unlock Podcast

Decoding Healthcare Transformation Through AI Top 5 Most Frequently Discussed Themes onThe Big Unlock Podcast Insights from Healthcare C-Suite Leaders on AI, Digital Health Innovations, Emerging Technologies (Insights extracted from 160+ episodes since 2018) Digital Transformation in Healthcare Patient Engagement and Experience Data Integration and Interoperability AI and Emerging Technologies in Healthcare Virtual Care and Telehealth Listen to the conversations and more on thebigunlock.com Where Healthcare C-Suite Leaders Decode Healthcare Transformation Through AI GuestsfrequentlydiscussDigitalTransformationJourney Terms like Machine Learning, Generative AI, and Automation come up regularly Conversations about data interoperability recur throughout This theme indicates a move toward more flexible, technology-enabled care delivery

Building the AI-Ready Health System: From Pilots to Autonomy

Building the AI-Ready Health System: From Pilots to Autonomy

As health systems seek to reduce clinician burden, improve operational efficiency, and deliver more personalized care, many are turning to AI—not just for automation, but for true autonomy. In a recent episode of The Big Unlock podcast, Shekar Ramanathan, Executive Director of Digital Transformation at Atlantic Health System, joined hosts Rohit Mahajan, Managing Partner and CEO and Ritu M. Uberoy, Managing Partner at Damo to discuss his healthcare journey, the promise of generative AI, and the importance of grounding innovation in practical, patient-centered strategies. Shekar believes that healthcare is on the verge of a major shift toward agentic AI, where intelligent systems can operate semi-independently to support both clinicians and patients.

A Strategic Approach to AI: Outcomes First, Technology Second

Atlantic Health’s journey began with a clear principle – work backwards from the outcome. “Our AI strategy is really around building kind of the framework,” Shekar explained. “It’s enabling the business, it’s understanding where the technology is going so that we can really be in a position to fully leverage it. That’s setting up the right governance, that’s setting up the right processes to be able to monitor AI, to make sure that it’s the right solution.”

This strategic clarity has allowed Atlantic Health System to identify high-value use cases across clinical and operational domains – from ambient scribing that streamlines documentation to intelligent message routing that directs patient queries efficiently. Each project is assessed not just on feasibility but on alignment with broader organizational goals and clinician workflows.

From Pilots to Practice: Real-World AI at Atlantic Health

Atlantic Health’s AI journey has evolved from early pilots to enterprise-level deployments. One standout example is their use of virtual medical assistants, tools designed to support patient outreach and engagement, especially for populations with lower digital affinity.

“We’ve focused on things like a virtual MA, where we can actually have more of a quasi-agentic approach for outreach, for patient communication, helping them manage their care,” Shekar said. These AI-driven assistants play a critical role in Atlantic’s commitment to health equity, helping underserved and digitally disconnected populations take a more active role in managing their care.

Another focus area has been scaling AI responsibly, which brings its own challenges. As use cases expand, so does the need for workforce training, process alignment, and robust governance. “Scalability becomes a challenge,” Shekar noted. “And then finding the ability to really, who are the right people that are going to be able to use the tools? How are we going to be able to extract value and not get just excited by the art of the possible?”

To address this, Atlantic is investing in AI maturity models, education programs, and a center of excellence that promotes cross-functional learning and best practices.

Scaling AI with Strategic Governance

Atlantic Health System is actively scaling generative AI across departments—from imaging and administrative operations to clinical workflows. But Shekar emphasized that innovation alone isn’t enough. Success depends on executive alignment, strong change management, and a well-defined governance framework.

He shared, “It’s easy to fall into the trap of chasing exciting new tools. But we’ve learned to step back and ask: Where is the real value? How does it improve patient care or clinician satisfaction?” His team has been intentional about bringing in stakeholders early, prioritizing trust and clarity, and avoiding “AI for the sake of AI.” The health system’s AI governance council plays a key role in evaluating use cases, setting guardrails, and ensuring ethical implementation.

One area where AI has made a tangible impact is radiology. Atlantic Health has deployed AI tools to reduce turnaround times in image interpretation and improve workflow efficiency. These successes are encouraging—but they’ve also brought new challenges, such as integrating solutions into existing systems and training clinicians to trust and adopt new processes. “We’ve had to rethink not just the tech, but the operating model that supports it,” Shekar noted.

Health Equity and Patient Engagement in a Diverse Community

Serving a geographically and demographically diverse population across New Jersey, Atlantic Health System is especially focused on health equity and digital inclusion. Shekar pointed out that many patients who could benefit the most from digital tools are often the least likely to access them due to limited digital literacy or socioeconomic barriers.

“How do we make digital care accessible to those who aren’t asking for an app?” he asked. “We’re working on outreach, education, and reducing friction—meeting patients where they are, not where the technology is.” Whether it’s language preferences, mobile access, or community partnerships, the organization is exploring ways to make digital transformation truly inclusive.

Unlocking the Next Chapter: Autonomy in Care Delivery

Looking to the future, Shekar identified agentic AI—systems that can act autonomously or semi-autonomously—as the next major shift in healthcare technology. These intelligent agents will be able to take on routine tasks, assist in decision-making, and streamline workflows, potentially reducing the administrative burden that has long plagued clinicians.

“Providers have been asked to do more and more over the years. With agentic AI, we have an opportunity to offload repetitive tasks so that clinicians can focus on what matters most—direct patient care,” he said.

He also anticipates a convergence of traditional generative AI and agentic models, creating hybrid systems that are both context-aware and capable of executing actions. But he was quick to note that progress must be balanced with thoughtful oversight. “We’ve moved at a glacial pace for years, and now suddenly we’re ready to sprint. It’s critical that we stay conscious of outcomes, ethics, and user trust as we scale.”

The Future of Healthcare: Insights from a CMIO on Technology and Patient Care

The Future of Healthcare: Insights from a CMIO on Technology and Patient Care

In a recent episode of the Big Unlock podcast, Priti Patel, MD, VP and Chief Medical Information Officer at John Muir Health, offered an insider’s perspective on how a community-based health system is leveraging digital innovation to enhance patient care, streamline provider workflows, and build a data-driven culture. With over two decades of experience as a family physician and clinical informaticist, Dr. Patel discussed how digital tools, particularly artificial intelligence (AI) and electronic health records (EHRs), are transforming patient care and clinician workflows.

The Evolving Role of the CMIO in Driving Health IT Adoption

Dr. Patel highlighted the evolving role of the CMIO as one that bridges the gap between clinical practice and information technology. Her team includes not just physicians but also nursing informaticists, reflecting a broader interdisciplinary approach to digital transformation. Dr. Patel mentions, “With clinical informatics, we really try to bridge the workflow with the technology.”

With strong foundational work laid by her predecessors, including EHR implementation and governance structures, Dr. Patel is now focused on building upon that legacy. She described how clinicians who once didn’t know the term “informatics” are now joining with formal degrees and certifications. This growth has helped embed informatics into every corner of the health system—clinicians, IT, operations, and leadership alike.

“IT is now part of every aspect of healthcare. We are seeing informatics grow beyond physicians—our nursing teams are deeply involved too,” Dr. Patel adds.

Ambient AI: Revolutionizing Clinician-Patient Interactions

One of the most transformative initiatives at John Muir Health is the adoption of ambient AI technology, specifically ambient scribe tools. Implemented in mid-2023, this technology allows physicians to focus on patients rather than documentation, addressing a long-standing pain point in healthcare. Dr. Patel noted that the enthusiasm for ambient AI was unprecedented, with physicians adopting the tool within hours due to its ability to reduce documentation time and enhance human connection.

Dr. Priti says, “the way we’re approaching ambient AI is that it should help reduce the cognitive burden, not just document a note. If it’s not improving the provider-patient interaction, then it’s not worth it.”

The integration of ambient AI with Epic was a game-changer. What started as a manual copy-paste process has evolved into seamless documentation support—now used by over 60% of providers, with some using it for 100% of encounters. Benefits include:

  • Up to 30 minutes saved per note
  • Reduced clinician fatigue
  • More face-to-face interaction with patients

Adoption came quickly—many providers embraced the tool within hours of deployment—driven by its usability and integration into existing workflows. Dr. Patel adds – “If the technology is designed well, it’s very easy to do. If it’s not designed with the end user in mind, change management becomes even more challenging.”

Building a Data-Driven Culture Through Literacy and Change Management

Dr. Patel’s team is also leading efforts to scale an enterprise-wide data strategy that centers on literacy, accessibility, and real-time insights. She highlighted the organization’s data literacy program, launched a year ago to empower clinicians and staff to leverage analytics tools effectively. Starting with one-on-one training for the C-suite and expanding to directors and managers through webinars and open office hours, the program significantly increased the use of dashboards and reporting tools.

This work supports a broader goal: turning raw data into actionable insights that support daily clinical and operational decisions. The learning curve is real—but the team is embracing tools like NLP and GenAI to simplify the analytics experience. Dr. Patel states, “We’re on this data-driven journey and teaching people how to leverage these self-service tools. There is quite the learning curve and that’s where natural language processing and gen AI may be very helpful.”

Balancing Innovation with Clinician and Patient Needs

Dr. Patel’s approach to innovation emphasizes the importance of change management in technology adoption. As a CMIO, she views herself as a change management agent, ensuring that new tools align with clinical workflows and user needs. She adds, “I think change management is the key to adoption; and adoption is the key to seeing the benefits of technology. That connection is really key.” This is particularly crucial when implementing technologies that may not be intuitively designed for end users.

Whether it’s through role-play testing for ambient AI or prioritizing tools that support clinician well-being, John Muir Health ensures innovation never comes at the expense of the user experience. Their digital strategy is firmly anchored to organizational priorities: improve patient care, reduce burnout, and enable high-quality outcomes.

The Road Ahead: Generative AI and the Future of Tech-Enabled Care

Dr. Patel is optimistic about the transformative potential of generative AI (GenAI) and agentic AI in healthcare. John Muir Health is actively exploring meaningful use cases such as drafting patient message responses, generating nursing care plans, and summarizing complex medical records to ease clinical workload. Predictive analytics tools are already helping detect early signs of sepsis, improve stroke care, and identify high-risk patients—laying a strong foundation for broader AI integration.

“I’m really interested in everything that’s out there and trying to find a solution that will fit our problems. That is always a challenge… how do you figure out what’s really going to make a big difference and improve patient care and the experience for our clinicians?” – Dr. Priti Patel

As the healthcare industry navigates this next wave of innovation, Dr. Patel emphasizes the importance of choosing GenAI solutions that address real clinical challenges and enhance both provider efficiency and patient outcomes.

When Technology Meets Care Management, Outcomes Improve.

Season 6: Episode #167

Podcast with Rob Posner, Chief Technology Officer, AbsoluteCare

When Technology Meets Care Management, Outcomes Improve.

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In this episode, Rob Posner, Chief Technology Officer, AbsoluteCare discusses how the organization is transforming care delivery through a member-centric, value-based model that emphasizes advanced care management and the social determinants of health.

Rob explains AbsoluteCare’s proactive, longitudinal care management approach – enabled by technology that empowers mobile care teams to engage with members wherever they are, whether at home, in the community, or within hospital settings. He underscores the importance of real-time data access, EMR availability at the point of care, and the role of transitional care managers in ensuring continuity post-discharge. Rob also emphasizes how governance, change management, and attention to operational details such as connectivity, mobility, and privacy are critical to success.

Rob also explores AbsoluteCare’s innovation strategy, including the use of ambient clinical documentation, AI-driven diabetic retinopathy screening, and organization-wide adoption of Microsoft Copilot. Rob shares his vision for the future of AI agents and robotic process automation to streamline workflows, reduce provider burden, and ultimately improve care outcomes. Take a listen

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Rob Posner is leading digital transformation as the Chief Technology Officer for AbsoluteCare. AbsoluteCare is a leading organization delivering primary and wrap around care to high utilization and acuity managed Medicaid members. Addressing health equity is a primary mission which drives our digital transformation agenda.

Previously, Mr. Posner was SVP for Pediatric Associates and led their technology transformation as it grew to become the national leader in office-based pediatrics. Prior to that, he established Envision Healthcare’s corporate Transformation Office integrating its merger of Envision and Sheridan Healthcare resulting in the largest hospital-based physician practice in the US.


Q. Hi, Rob I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting, and host of The Big Unlock podcast. It’s been a popular show for many years, and we’re continuing the tradition started by Patty Padmanabhan, the founder of Damo Consulting. Many healthcare leaders have been on this podcast, and it’s great to welcome you. Over to you for your introduction, Rob.

Rob: Terrific, Rohit. It’s a pleasure to spend time with you and with your audience. I’m Rob Posner. I’m the Chief Technology Officer for AbsoluteCare. I’ve been with AbsoluteCare for about two and a half years now. I joined because of the game-changing mission of this organization. I’ll get into that in a moment, but first, a little background.

Prior to AbsoluteCare, I spent the last decade in similar private equity–backed, provider-centric organizations that are changing healthcare. My passion for healthcare has really been about the transformation that’s needed—not just for those organizations, but for the country and the world. I truly believe in that mission and the role technology plays in achieving it. That’s why I decided to move into the healthcare industry.

Before that, I was in hospitality and entertainment. I live in South Florida, and the cruise lines are big here. I’ve worked with major cruise lines and Disney Parks in particular. I built a team and worked backstage at Disney Parks where we developed the MyMagic+ experience and led major aspects of that global rollout—transitioning to a managed guest experience. It was one of the early efforts in what’s now known as the experience economy, leading products and services by experience for consumers and guests.

Q. That’s awesome, Rob. I’m actually a fan, and I don’t think I mentioned this to you last time—Disney has a university where they run programs on leadership, quality, service, and a few other topics. I’ve been through all four of those. So great to know that background. Now that you’re at a healthcare organization, could you tell us more about AbsoluteCare—what the business model is, and how it aligns with your experience in provider-centric organizations that are really changing the healthcare industry?

Rob: Absolutely. AbsoluteCare’s mission is to improve the healthcare of the nation’s most vulnerable populations. We do this by improving outcomes through holistic care and care management.

We refer to those we serve as members—not patients—because we contract with payers for a panel of their members. So they become our members, and we take full responsibility for their care. Our tagline is “Beyond Medicine” because we deliver primary care, care management, pharmacy, behavioral health, and address social determinants of health in a comprehensive way. That’s what differentiates us from traditional care models.

We operate under a full-risk, value-based care model that demonstrates improved outcomes. We’re fully accountable—clinically and financially—for delivering on the triple aim of healthcare. We don’t just talk about it; we live it. That accountability is central to being a sustainable and impactful organization.

Q. And, and I understand you are in several markets and tens of thousands of patients now, so there must be some early learnings. 

Rob: We are rapidly growing. We were in seven markets at the end of 2024, and we’re about to be in 11 markets over the next couple of months. We serve tens of thousands of high-acuity, high-utilization managed Medicaid members. That’s important to understand—these are some of the nation’s most vulnerable individuals. They often have multiple chronic conditions, compounded by social determinants of health. We need to address all of those factors to be successful. 

Q. That’s awesome. And your delivery model is partly center-based and partly community-based, right? That seems like something unique AbsoluteCare brings to the table. 

Rob: Absolutely. We deliver about half of our care in our centers and the other half in the community. In each of our markets, we have a center located in the urban core to serve our members. But the reality is, it’s often difficult for our members to reach us. Since we’re responsible for their outcomes, it’s on us to go to them—wherever they are—to ensure we’re delivering care and care management that drives better outcomes.

Q. That’s amazing. I have a curious question—from my perspective. You mentioned that you get the cohort of patients from the payer side, right? Because they obviously want better outcomes. So, do you work with providers at all?

Rob: Our organization includes providers. In other words, we deliver the actual care. We have our own employed providers who deliver primary care services. We also employ care management teams, behavioral health specialists, and pharmacists who work in our pharmacies. So we provide comprehensive care and care management in our centers. Additionally, our providers and care teams go into the community to deliver care in members’ homes and other facilities. 

Q. So I understand that there’s a lot of technology at play here. Obviously, we are all leveraging all kinds of technologies to help better outcomes for these members and for these patient populations. So, would you please talk to us about your journey? Like how was Absolute care and then the how did you fast track? I think you were talking about fast tracking transformation. 

Rob: Oh, absolutely. Yeah. So I’m the first C-level IT executive in the organization. And not surprisingly, that means that usually there was—coming into it, I think the teams were doing the best they could with what they had, but they didn’t have a seat at the executive table. And so we found that the state of technology was not where it needed to be. And of course, that’s why they brought in a Chief Technology Officer.

So nothing was really surprising from that perspective. But systems were not configured for our mission. It’s not unusual because systems are not really made or designed—typical EMRs are not designed—for value-based care, full-risk provider models, right? So it’s not surprising they weren’t configured correctly.

The technology team was following the business rather than leading. There was a lack of appropriate governance. And like I mentioned, the teams were working really hard, and I’m proud of the work they did to get to that point. But clearly the organization recognized that more needed to be done.

Just to explain the point—when I got there, within a month or so, we had a terrible situation where we had a significant outage of our EMR that went on for more than a day. And no one in the organization thought to tell me. Our EMR—which all of our providers and care management count on to do their jobs every day—was down. And she let me know that we were down. So it was the kind of thing where we had to change the culture, change expectations, and deal with accountability.

That was kind of the start of that story—saying, okay, that’s where we were. I installed new leadership within my department, got people who understood where we need to go, how to set expectations for our teams, reset what operational excellence means, and establish that culture of accountability.

We worked very rapidly to start reconfiguring our EMR. Even in terms of the governance—we had a steering committee for our EMR, but what we found was a whole bunch of leaders were sitting on calls that should be about strategy, and they were dealing with day-to-day issues. That pointed to the fact that we didn’t structure our governance well. We didn’t have core teams and the right people dealing with the day-to-day so we could address those, and then separately deal with things like: should we be moving to the cloud? Should we be on one instance of the EMR?

These things have to run in parallel, and you have to have the right people engaged in those conversations—and the right cadence. Those are some of the things we had to do very quickly to start dealing with the rapid transformation that we needed to make as an organization.

Q. Right. And you really had to do groundbreaking—or from the grassroots—you had to build a care management system, because the EMR really isn’t suited for that purpose, right? So please talk to us about that. It’s something very different, I guess, that you’ve done in the organization, and it’s like the bedrock for engagement.

Rob: Absolutely. And just about all EMRs you could categorize as being focused on delivering care in an office, in an ambulatory environment. What does that mean? For a patient visit, a member visit, in a center. That’s really what it’s designed to do.

But when you talk about all the work we need to do to provide longitudinal care for that member—it’s the things happening 99% of the time when they’re not in the doctor’s office. That’s care management, and that’s where a lot of the outcomes for our patients happen. But it’s not really addressed in EMRs. EMRs look at things like decision support for the doctor and care gap closures, but care management is its own thing. It has its own workflows, and we need to make sure they’re focused on what produces improved outcomes.

So, we determined that EMRs don’t really do that, and we brought in a full-fledged care management system. We implemented that and went live about a year ago. We also integrated it with our EMR, which at the time was a fairly significant step, because the objective was to let people work from one pane of glass.

If they’re in the EMR, they shouldn’t need to jump into the care management system to check on something—and vice versa. That’s been a journey. We’ve done the first couple of iterations to make it work. There’s more to do, but we’ve gotten our MVP product into the hands of our markets, and it’s being used successfully. It’s been a great success story, showing how we can integrate care and care management in a way that reflects our model. We have a care model, and we need to make sure our systems are aligned with that—not force people to work within systems that don’t fit.

Q. Absolutely. That’s significant. And it’ll always need to be taken to the next level, based on user feedback and the people who engage with it. So we talked about care management, Rob, and it’s fantastic that you were able to build a product to engage members and support all the stakeholders. How did you think about the tech stack? Because you’re operating at two levels, right—like we discussed before, also out in the communities?

Rob: Absolutely. And from what I’ve seen in the industry, these systems are typically designed to work in a facility—an office or a hospital—or maybe a hospital-at-home type setting. The assumption is that the technology stays in one place: someone is a remote worker, someone is working in a hospital, etc.

But in our integrated model, that’s not the case. We’re delivering half of our care and care management in people’s homes, which means our workforce is mobile. They’re in the field, moving between members’ homes. We have transitional care managers who go out into facilities when we get an alert that a member’s been admitted to the hospital or has visited the ED.

So we need systems that can work across a variety of environments. Our original tech stack wasn’t built for that—it was built for more stationary settings. So we had to completely rethink it. We tested different laptops, connectivity solutions, and carriers until we found a solution that worked. We looked at each market individually, since different carriers perform differently depending on the location.

We landed on a solution that includes new high-powered laptops, MiFi devices, and iPhone 15s. It turned out that the 5G technology—and specifically the antennas on that hardware—allowed us to overcome many earlier challenges. 5G really opened up the capability and gave us the bandwidth we needed to connect to an EMR in the field.

And once we did that, it really unlocked the power of our solution. I saw that firsthand when I did a round with our transitional care managers. One of them was at the bedside of a member who had been admitted to the hospital. Their job is to coordinate care, make sure follow-up appointments are scheduled so we can continue to support the member.

And right there at the bedside, the care manager was able to open the EMR, schedule the appointment, confirm it with the member, and ensure continuity of care. That’s exactly what we need to see—technology working in the field, making a real difference in the care and care management we deliver.

Q. That’s awesome. Yeah. Being able to schedule appointments at the bedside is, is fantastic. Even today to reschedule my appointment with my physician is a big task.

Tell us, you know, uh, Rob, that in building all these solutions to solve the problems that you saw, how did you go about the governance aspect of it? 

Rob: Yeah, governance is a really important aspect here. It’s really easy to focus on what system you use—there are great enterprise solutions for most of the challenges we face in healthcare, broadly speaking. We have our in-house pharmacy, so we implemented a pharmacy system. We have a care management system, our primary EMR—so we have the big pillars, if you will, of our clinical applications.

But what’s really important to unlock the value of those systems is establishing product teams, having effective steering committees, and creating a proper intake management process. It’s so easy to get lost in all the new requests that come in. You need a way to manage that, making sure we stay aligned with the business—both in terms of the strategic plan and the day-to-day changes happening.

So you have to manage between the strategic and the tactical. You can’t just do one or the other or you won’t be successful. Keeping that executive alignment—engaging the appropriate executives at the right times—and having an overall change management and governance approach are all key building blocks. If you don’t have these things, it doesn’t matter what systems you put in place—you’re not going to be successful.

And I think another point—not governance in particular, but related—is not forgetting the small things. Like I mentioned earlier about the community tech stack—one of the things we didn’t think about was the equipment itself. You’ve got to pilot everything. Don’t go live with anything without piloting it, because that’s where you learn the small things that make a big difference.

For example, we provided all this technology, but we didn’t have the right type of briefcases for the care management team. We eventually got them rolling bags—and they had to be locking bags—because of PHI. We’re a HITRUST-certified organization, which is business-critical to us. So we take the handling of patient information very seriously.

Those are the kinds of things that make a difference. If you don’t take care of the little things, you don’t get the adoption—and then you don’t see the business results. Which is why, at the end of the day, you’ve got to think about the big things and the little things. And together, that’s what makes a solution really work for the organization.

Q. That’s great. So Rob, no podcast would be complete without touching on AI and innovation. So, would love to get your thoughts on innovation, AI, and now GenAI. What are you thinking, and what are some of the use cases you might be coming up with? 

Rob: Sure. Look, AI is a really exciting topic in the industry, and for us in particular, I’m really excited about what we’ve been able to accomplish recently, and equally excited about the opportunities in the future.

So on the clinical side, rolling out ambient experience—ambient listening for clinical notes—is the critical use case. We’ve been able to implement that successfully. We went from pilot very rapidly to full rollout. We saw the results very quickly. And look, there’s a lot of change management to do with the providers—to get them used to the fact that this ambient listening device is there, making sure they’re talking to their patients about it and what it means, and how to leverage it effectively. And so that’s a learning process, and we’re definitely still going through that, but we’re already seeing results.

One of the immediate results is that our providers can engage our members more effectively, right? At the end of the day, they’re spending less time hands on keyboard, and more time engaging with our members, having the important conversations that they need to have to deliver care. And so that’s really exciting in terms of the impact on care delivery and outcomes.

Another piece on the clinical side—we implemented a system that detects diabetic retinopathy with fundus cameras. The solution takes the images in the office, sends them immediately to our partner in the cloud, they do a read of those images, and send back—within 30 seconds—a result and a recommendation for referral. What we’re seeing is that because we get that instantaneous result, our patients—our members—are actually going forward and getting that referral and follow-up appointment. And that’s really what we’re talking about: we’re changing the behavior of our members so they get better outcomes, address diabetic retinopathy early, and take care of it before it leads to something as serious as blindness. It’s a really urgent issue, and here’s an example where technology is really motivating our members to take care of their health. That’s amazing and exciting to see.

Additionally, we’re starting to see AI throughout all of our systems—it’s just almost happening organically, I would say, just by vendors providing it. So, certainly Microsoft Copilot, which has become pretty ubiquitous—we’ve rolled that out. We piloted it, saw great results, saw great adoption. I’d say of all the technologies that we’ve released, Copilot was one where we just put it out there, gave some training and tips and tricks, and the uptake was amazing. Unlike an EMR, where providers are required to use it and follow detailed workflows, with Copilot there was no requirement—and still the adoption was high. We’re seeing great productivity results and people learning how they can use AI in their day-to-day work. And that just rolled out recently. We expect to do a lot more with it. We’re doing workshops to enhance learning and help staff understand what’s possible with AI.

So that’s what we’ve implemented so far—those are active in our organization at the enterprise level. In terms of where we go from here, there are a couple of areas that are very exciting to us. Robotic process automation—though it’s not new—is an area where we can continue to refine the EMR experience for our providers and frontline staff. We’ll continue to look at automation opportunities and other AI capabilities within the EMR, like documentation and note summarization, translating into different languages to communicate better with patients, and reducing the multi-click environment of the EMR by automating routine tasks. The next area is really AI agents—looking at what’s happening outside our core platforms that could be managed with more automation and integration. That way, we can free up our team members to focus on what really matters—our members.

Q. That’s awesome, We actually did a seminar today, Rob, on Agentic AI in healthcare, and there was a great response to the webinar. It’s such an interesting topic—people are actively looking for use cases. We’ve worked on several use cases with our clients, and we definitely see Agentic AI as one of the key options to explore.

So I think we’re toward the end of our podcast, Rob. Any final thoughts or remarks you’d like to share with the audience?

Rob: Yeah, I would just say that it’s a really exciting time to be in healthcare technology. I believe we’re at a point of inflection—where not only do we as healthcare technologists see the opportunity, but the business side clearly sees it as well and is relying on the technology function to step up.

And I think that’s happening—as executive leaders begin to expect more from their technologists, but also expect the business side to think about how to leverage technology. That’s where we’ll really start to see the tech and business teams working together to solve meaningful problems and drive real impact.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Driving Digital Transformation With AI, Voice Bots, and the Power of Starting Small

Driving Digital Transformation With AI, Voice Bots, and the Power of Starting Small

In a recent episode of The Big Unlock podcast, Crystal Broj, Enterprise Chief Digital Transformation Officer at the Medical University of South Carolina (MUSC), shared a compelling account of how her team is reshaping healthcare delivery through AI-driven innovation. Crystal talks about how MUSC is transforming healthcare through AI-powered voice bots, ambient listening, digital front door innovations, the challenges and successes of implementing a new patient check-in system and deploying an automated AI agent in their patient access center.

From piloting intelligent automation to enhancing patient access and provider efficiency, MUSC’s digital journey offers valuable lessons for any healthcare leader navigating transformation.

Start Small, Scale with Purpose

One of the biggest lessons Crystal emphasized was the value of starting small and scaling smart. MUSC began its digital transformation journey with a pilot using Notable to send appointment reminders to patients at just five clinics. After carefully evaluating feedback, the initiative expanded across the organization. This phased approach allowed MUSC to iterate, build internal trust, and grow digital capabilities with confidence.

“One of the biggest lessons learned is yes, start small and then move forward,” Crystal explained. “We didn’t try to make everything perfect—we added little pieces thoughtfully.”

AI Accelerates Access and Reduces Manual Burden

A standout success story is the implementation of an automated AI agent to handle prior authorizations. This task—once requiring 15 to 30 minutes of manual data entry and payer coordination—is now done in about 30 seconds by AI.

“We have about a 37% accuracy on this agent, and it keeps learning all the time. That means almost 40% of the ones we send through are done without any human intervention.”

This innovation not only accelerates care for patients but frees up staff time for more complex needs. By automating a time-intensive administrative process, MUSC improves both efficiency and the patient experience.

Voice Bot Redefines Patient Access

Another game-changing technology has been the deployment of a voice bot named “Emily” in MUSC’s patient access center, which handles 42 phone lines and approximately 150 agents.
Emily uses natural language processing to greet patients, validate appointments, and provide key information—all without involving a human agent. The bot now deflects 17% of incoming calls, reducing wait times and call center volume while allowing staff to focus on more complex patient concerns.

“We’re not getting rid of jobs,” Crystal clarified. “But our access reps can now handle more complex questions. Our hold times have gone down, and hang-up rates have dropped.”

Beyond regular business hours, Emily also provides 24/7 support, and she is being trained to handle appointment rescheduling and Spanish-language interactions. With plans to roll Emily out to additional departments like revenue cycle and pharmacy, the bot is poised to become a foundational tool in MUSC’s digital infrastructure.

The Importance of Testing and Change Management

Crystal stressed that rigorous testing and thoughtful change management are critical to successful implementation. When deploying voice tech like Emily, MUSC took the time to train the bot on regional accents, common phrasing, and different user needs to ensure a seamless experience.

“Testing is really important—getting the people who are going to use the software to test it helps us understand what patients are actually hearing.”

Equally important was managing the human side of change. Staff had to be retrained, new workflows created, and consistent communication ensured. For example, front desk teams were used to handing out clipboards for patient check-ins—now they needed to trust the technology and guide patients through digital check-in instead.

Real Metrics, Real Impact

MUSC rigorously tracks key performance indicators (KPIs) and return on investment (ROI) across its digital initiatives. These include:

  • $1.4 million collected in copays through pre-visit engagement,
  • $1.9 million in open balances recovered via automated tools,
  • 98% patient satisfaction with the Notable platform,
  • 37% reduction in “pajama time” (after-hours charting) for doctors using ambient AI documentation tools,
  • Over 1.7 million reminders sent to patients since June.

These metrics are reported monthly to business and clinical leadership, demonstrating tangible value from the digital investments.

Transparent Scheduling and Digital Front Door Improvements

To improve access and meet patient expectations, MUSC has also implemented DexCare, a natural language-powered “Find a Doctor” tool integrated into their website. Patients can search using everyday terms (e.g., “elbow pain”) and immediately see available appointments—both in-person and virtual.

This initiative has already resulted in 200+ self-scheduled appointments in its first week, even without promotion. Crystal believes this level of transparency will be vital in shaping the modern digital front door.

“Our patients are asking for access. Now they can see what’s available and take action right away.”

Challenges on the Road to Transformation

Of course, transformation is not without its challenges. Crystal pointed to IT staffing limitations, the need for ongoing support from cross-functional teams, and the unpredictability of integrating with legacy systems. Agile planning, flexible timelines, and close collaboration with vendors and internal partners have been key to overcoming these hurdles.

Crystal also highlighted the need to address provider resistance, particularly with ambient AI documentation tools. While the tools helped reduce after-hours work and accelerate documentation, some physicians were initially hesitant. MUSC had to adjust its communication strategy, provide more hands-on support, and build confidence over time.

Looking Ahead: A Seamless Experience for Patients

When asked about the future, Crystal envisions a healthcare experience where digital tools support seamless navigation before, during, and after a patient’s visit.

MUSC’s digital transformation journey—under Crystal Broj’s leadership—proves that healthcare innovation doesn’t have to start with massive disruption. By starting small, tracking real outcomes, and scaling intentionally, the organization is using AI and automation to solve real-world problems, improve care access, and empower its workforce.

For healthcare leaders navigating similar paths, the message is clear: start small, measure impact, and move forward with purpose.

Keeping Humans in the Loop: How Pager Health Is Scaling GenAI Responsibly

Keeping Humans in the Loop: How Pager Health Is Scaling GenAI Responsibly

Generative AI is rapidly transforming the healthcare landscape, offering new possibilities for care delivery, patient engagement, and operational efficiency. Yet as organizations rush to adopt AI solutions, one healthcare innovator is reminding the industry that trust, responsibility, and human oversight must remain central to any implementation strategy.

In the recent episode of The Big Unlock podcast, Rita Sharma, Chief Product Officer at Pager Health, shared how her team is scaling GenAI thoughtfully—with an approach grounded in data transparency, human-centered design, and trust-building with both clinical teams and healthcare consumers.

A Strong Foundation: Data Transparency and Governance

Pager Health’s GenAI journey commenced not with high-visibility pilots or rapid experimentation, but with a deliberate focus on foundational strategy and internal preparedness. Instead, the first step was inward-facing: establishing a clear and rigorous framework for data usage, transparency, and security.

“We had to make sure that we had a really strong framework internally for how we think about data usage, transparency, and security before we started scaling GenAI use cases externally,” Rita explained.

This internal discipline gave Pager the confidence—and credibility—to move quickly and responsibly. By investing early in robust data governance, the company signaled to health plan partners, providers, and regulators that it was serious about ethical AI practices. That foundation helped accelerate deployment later, because core trust and compliance concerns were already addressed.

Consumers Are Ready—But Trust Is Key

Despite initial skepticism in the healthcare industry, Rita sees a clear shift in how people view AI—especially the end users. “What I think is so exciting,” she said, “is that the consumer has said, I trust AI.”

According to Pager Health’s recent national consumer experience survey, more patients than ever are willing to engage with AI-powered tools to manage their health. Part of that trust, Rita noted, stems from increased familiarity—people use AI daily in search engines, smart assistants, and apps, so the idea of AI in healthcare no longer feels foreign.

But growing trust also depends on how the technology is used. Patients are more likely to embrace AI when it feels empathetic, accurate, and useful—not abstract or robotic. That’s why Pager’s approach is built around intelligent AI agents that understand user context, act with empathy, and support care decisions in collaboration with human providers.

Keeping Humans in the Loop

One of Pager’s core philosophies is that AI should never operate in isolation—especially when it comes to healthcare decisions. Human involvement remains essential to creating safe, trustworthy, and effective care experiences.

“We have to keep the humans in the loop… it’s going to be super, super, super helpful to us because we can start to build more and more trust with the end consumer,” Rita emphasized.

Rather than viewing AI as a replacement for clinicians or care teams, Pager uses GenAI to extend human capabilities. Whether it’s simplifying patient navigation, providing clinical summaries, or managing complex workflows, AI at Pager acts as an enabler—not a substitute.

This human-in-the-loop model doesn’t just ensure safety and accuracy. It also builds confidence with patients, who are far more likely to embrace technology when they know a real person is still overseeing their care.

Balancing Efficiency with Oversight

Pager’s GenAI innovations are impressive—from AI-powered navigation tools for health plan members to ambient technologies supporting provider workflows. But the company isn’t chasing automation for its own sake. The goal is to achieve scale and speed without sacrificing accountability or empathy.

“We can make huge progress if we blend efficiency with the right level of human oversight,” Rita explained. “While GenAI isn’t brand-new, the way we’re applying it in healthcare is—and that demands a thoughtful, deliberate approach.”

This mindset is helping Pager scale rapidly without losing sight of the human relationships that define good care. By augmenting clinical teams instead of replacing them, Pager makes it possible to support larger populations without compromising quality or trust.

What This Means for the Future of AI in Healthcare

Pager Health’s story highlights a crucial lesson for the healthcare industry: GenAI’s success doesn’t hinge on algorithms alone—it depends on how responsibly we design, deploy, and govern these tools.

By investing early in data governance, keeping humans central to decision-making, and listening to consumer sentiment, Pager is showing that it’s possible to harness the power of AI while preserving trust and empathy.

The industry is watching closely. As more health plans, providers, and digital health startups consider scaling their own GenAI initiatives, Pager’s approach offers a replicable model—one that balances innovation with integrity.

Why Trust and Transparency Must Lead the GenAI Revolution

Pager Health’s journey offers a valuable blueprint for healthcare organizations navigating the GenAI frontier. It’s a reminder that success with AI doesn’t hinge on flashy use cases or cutting-edge algorithms—it depends on how responsibly we design, deploy, and govern these tools.

By building a strong internal framework, prioritizing human oversight, and listening to what patients actually want, Pager is showing how GenAI can be scaled without sacrificing safety, empathy, or trust. As Rita Sharma put it, “If we keep humans in the loop and focus on efficiency, we’re going to see amazing inroads with GenAI.”

As the healthcare industry continues to explore AI integration, Pager’s example is both inspiring and instructive. GenAI has the potential to be a powerful force for good—but only if we remember that at its best, technology should amplify human care, not replace it.

Transforming Prior Authorization with AI

Season 6: Episode #166

Podcast with Siva Namasivayam, Chief Executive Officer, Cohere Health

Transforming Prior Authorization with AI

To receive regular updates 

In this episode, Siva Namasivayam, Chief Executive Officer of Cohere Health, discusses the challenges and opportunities in overhauling the prior authorization process in healthcare. 

He shares how AI is being applied to reduce administrative delays, including the use of generative AI to summarize clinical data and intelligent agents to assist with scheduling and information retrieval processes. The conversation also touches on enabling real-time approvals for a majority of cases, designing algorithms informed by physician input, and navigating the shift to remote work. The discussion offers insight into how technology can address systemic inefficiencies while maintaining clinical oversight. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

In his third entrepreneurial healthcare venture, Siva Namasivayam is passionate about building companies focused on improving the healthcare system.

Prior to co-founding Cohere Health and serving as its CEO since 2019, Siva was a founder and CEO of SCIO Health Analytics - a healthcare predictive analytics company for health plans, providers, life sciences, and pharmacy benefit managers. The company was acquired by EXL for $250M in 2018. Siva has more than 20 years of experience in utilizing technology and data to improve healthcare processes. He holds a master’s in computer science from the University of Pittsburgh, as well as an M.B.A. from the University of Michigan.


Q. Hi Siva. How are you doing today? Welcome to The Big Unlock podcast. Very happy to have you as our guest today. For our audience, as you might be aware, this was started by Paddy Padmanabhan, and I’m building on his legacy. We’ve done many episodes. Let’s do some quick introductions. I’ll start. I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting, and also the host of The Big Unlock podcast. Over to you.

Siva: Wonderful. Appreciate you having me on the podcast, Rohit.
I’m the CEO and co-founder of a company called Cohere Health. We started in late 2019, and we are solving the burdensome issues related to prior authorization.

I’ve been in the healthcare industry for more than 25 years. Prior to Cohere Health, I founded another company called Coda Health Analytics in 2007, built it over 10 years, and sold it in 2018 to EXL. It was a successful analytics company in the healthcare market, funded by VCs including Sequoia Capital. It was a good exit for everyone. We were serving health plans at the time.

Before Coda Health, I started a small company in the provider space and sold it to Perot Systems. I also started my career at Intel, then went to business school at the University of Michigan, got my MBA, and moved to Connecticut. I live in Connecticut now and came here to work for Gartner Group. From there, I wanted to start something on my own, and that’s how I began my healthcare career.

Q. That’s amazing, Siva. Thank you for that introduction. With such successful exits, I’m sure Cohere will also be on a great footing. Could you share how the idea for Cohere came about? You’re so familiar with the healthcare space—I’m sure you saw a big problem to solve. How did it start, and what’s your journey been like?

Siva: As I indicated, in my previous company, I had been working closely with the health plans—health insurance companies. We were doing analytics, and at that time, we were focused a lot more on payments, population health management, care management, etc.

During that process, I came across the prior authorization process, which the health plans were involved with. I’ll get into more detail about prior auth later. So I got involved in that, and it was always in the back of my mind that the process was highly manual and caused a lot of operational issues for both providers and patients.

It was a major pain point for the health plans. After I sold the company, I had to work there for a bit. And then I started thinking: how can we apply AI and other advanced technologies to solve this problem in the healthcare ecosystem? That was my angle.

While I was working with the health plans earlier, some of my clients had indicated they’d be willing to work on this problem—if I could come up with a better solution. That’s how I kind of got into this.

Q. That’s amazing to know that you were able to discover a gap and then build a new business enterprise to fill that gap. So tell us, Siva, a little bit more about prior auth. Most people in healthcare know what prior auth is, but tell us some of the intricacies and more details about it. You’re the expert on it, right?  

Siva: Sure. Prior authorization is, you know—as a patient, for example—when you go to a specialist, they’ll usually examine you. Say you go there for knee pain. Depending on the severity, they might just take an X-ray first to see what the problem is. If it seems more acute, they might order an MRI.

Now, the moment a physician orders something more expensive—like an MRI, which can cost between $1,500 and $2,000—the insurance company wants to know why that test is being ordered. So the physician’s office has to fax or submit information explaining why I need the MRI.

Then, the health plan looks at their policy and decides whether to approve it. So that’s the process. Anytime there’s a costly or potentially unnecessary procedure being considered, this process acts as a check and balance to ensure it’s appropriate.

On the insurance company side, the submission process itself can be confusing. It might happen through a portal, a fax, or a phone call. Then, the health plan assigns it to a nurse, who reviews the information and determines if it aligns with policy. If it does, they approve it.

If the nurse thinks it doesn’t meet the criteria, it goes to an MD for review. The MD might then say, “You don’t need it,” and deny it—or they might approve it. If it’s denied, it’s usually by a specialist on the insurance side who gives a reason—like saying based on the X-ray, the issue doesn’t look serious, so physical therapy might be enough.

My physician might not agree with that, but that’s the process. So then they might send me for conservative therapy, etc. That’s the prior authorization process.

Q. Okay. And Siva, in the first part of what you were explaining, you used the word abrasion, right? I’m very curious—what is this abrasion that’s happening? And second, how long does this process take? Because now the person needs to apply, right? 

Siva: Yes. Right, exactly.

So the process hasn’t always been very clear in terms of what information needs to be submitted. What happens is there can be a lot of back and forth between the physician’s office and the insurance company. For example, the office sends some information, and the insurer says, “No, no, we’re looking for an indication of something else.” Then it gets sent back. The provider looks at the documentation and says, “No, we actually did provide that—here’s where it is,” and they send it again.

So that back and forth adds time and creates more administrative work on both sides.

All this paperwork, documentation, back-and-forth communication, and waiting can take anywhere from five to 14 days. For very complex procedures, it could even take 13 to 14 days. For example, if someone needs surgery, they might have to wait while going through multiple rounds of paperwork and approvals.

Meanwhile, the patient is the one who suffers. The final decision—whether it’s approved or denied—won’t be known until that whole process is complete, and only then can the surgery be scheduled.

That’s what causes the abrasion: the administrative burden, the delays, the unclear requirements, and the possibility of denial at the end of a long process. And that’s still the case in many areas today.

Q. So because of your prior experience with payers, in this particular case insurance companies, you chose to focus on prior auth with them. And there is the healthcare system in the loop, which is the physicians and the providers. How do you distinguish between the two? Because prior auth is important from both perspectives, right?

Siva: For the health plans, it’s a cost. The main reason why there is prior authorization is because, as we all know, healthcare costs have been going through the roof.
There is quite a bit of waste, and a lot of it is due to unnecessary procedures, unnecessary imaging. For example, there’s no need to do imaging if it’s sufficient to have just an X-ray, which costs like 50 bucks instead of a $1,500 or $2,000 scan.
Because of the excessive use of high-cost items, there’s waste in the system. Health plans, being the intermediaries, manage the dollars for employers or the government, like Medicare.
So one of their tasks is to control for this. The health plan’s viewpoint is to prevent unnecessary things.

Obviously, the physician thinks something is very important for the patient, and that’s where the tension is.
The reason we decided to go with the payer side is that payers have the volume, and a lot of things can be controlled from the health plan side using technology.

There’s no point in just speeding up the process on the physician side. There are benefits to it, but you’d have to do it for every physician office.
If you go to the health plan, you can address all of this in one shot.

Q. Awesome. So Shiva, you mentioned that you started in late 2019. So that’s actually before COVID, right? 

Siva: Yeah. That’s like three months before COVID. 

Q. And then COVID hit. It must have impacted your go-to-market and your plans. But you stuck to the mission. You have very good investors who’ve supported you in your journey.
Tell us a little about the bumps on the road, how you overcame them, and where you are today. How many employees, and how are you going about this?

Siva: One of the things is that we actually managed to partner with a large health plan—okay, Humana—it’s on our website. What happened was that I had hired like four people or so. We were actually working in a WeWork office in Boston in February and were in the process of finding an office and recruiting people, etc.

I remember in early March 2020, while working in the office, they called all of us down and said, “Hey, we found somebody with COVID today in the offices. So you guys have to go home. We will call you, and we’ll see when you can come back.”

That was the last time we all saw each other—the four of us. And we came home, and after that, we didn’t see each other for more than a year.

But then we changed our entire plan—worked remotely—and built the product out. They had a deadline of January 1, a client. So January 1st, 2021. We said, “We can’t just sit at home and wait for COVID to go. We need to develop the product and everything else.”

We actually took advantage of the remote situation because initially our office was going to be in Boston, and we were going to recruit engineers in Boston—everybody in Boston. But because of COVID, we said, “You know what? We can hire people anywhere in the country.” And so that actually opened up the pool for us. We went around the country and recruited people from all over.

Q. That’s amazing. And I understand you’re still fully remote, which is very different from many companies shifting to hybrid or back to the office.
So tell us—what’s the secret sauce for keeping people engaged? You’re up to several hundred people now, so how do you keep such a large team engaged remotely?

Siva: It’s not easy. By the beginning of 2023, when things were becoming more normal, we were already up to 400 people across the country.
We didn’t have a choice. A substantial number were in Boston, but that was only about 35%.

So we continued with the remote model but tried to make it more efficient. There are pros and cons. We manage it by making sure management and teams meet regularly.

Our travel budget is high, but since we save on office space, we spend on getting people together. From a management team perspective, we meet once a quarter.

We also have regular team meetings—sales, clinicians, operations, technology, AI, product—each meets in different parts of the country throughout the year. That’s important for building camaraderie.

Q. That’s amazing. And from a time zone perspective, since everyone is in the U.S., that works well. We’ll talk about expansion plans in a bit, but you just mentioned AI. Tell us how you’re applying AI, GenAI, and agents in your product development. Things are moving fast with GenAI.

Siva: In fact, from day one, our goal was—let’s try to provide real-time approvals instead of the usual five to seven days. At the end of those five or six days, if it’s going to be approved anyway, why not do it immediately if the information is there? So we focused on how to approve things faster.

We found that at the end of the prior authorization process, 80 to 85% of requests are usually approved. So we said, let’s focus on that and use AI to approve—not deny—because denial still needs to be reviewed by a nurse or MD. So we focused first on solving that piece.

Today, we approve about 80 to 85% of requests in real time. That’s where AI comes in. We use AI in six or seven different ways on our platform. One of the main ones is this: we get the EMR or medical record from the provider’s office and ask what service is needed. Then, we analyze the unstructured data—diagnosis, patient history, etc.—and determine whether the treatment is clinically appropriate based on certain policies.

For that, our physicians review the algorithms to ensure they’re clinically sound. We have about 50 physicians in the company across multiple specialties. They review the information and help us encode that into the algorithms. It’s a painstaking process, but that’s how we reached 80%, and we’re still improving.

If there’s any doubt about a request, it goes to an MD. We never use AI to deny care—we leave that decision to physicians, who then communicate with other physicians. That’s one big area where we use AI.

We also use GenAI for scheduling patients, retrieving missing information, and automating tasks like converting faxes into structured data. We have intelligent agents that complete entire workflows. Summarization is another area—we use GenAI for documentation and generating letters. We’ve been an AI-native company from day one.

This has helped reduce abrasion because users know that 85–90% of the time, they’ll get an answer immediately. That’s a huge win—they don’t have to wait or reschedule.

We do quarterly user surveys. Our NPS is between 65 and 67—very high. Providers are saying, “Okay, someone is finally solving prior auth,” and that’s one of our biggest outcomes.

For the remaining 15% of requests that still need more review, we’re now working to bring that timeline down to one or two days using AI. We’re able to summarize and present all necessary information so physicians can quickly review and approve it—or reach out to another doctor for a quick consult. So AI is helping us shrink that review time, too.

That’s how we’re deploying AI across the board.

Q. Very interesting. Siva. So that brings me to my next question actually, that when you consider the benchmark of companies or your landscape in which you are doing your competitive positioning, are there any other large players that are in the same space and different and unique and how do you position yourself?  

Siva: The process has been there for more than 30 years. So there are legacy companies that have been doing this for health plans. Yeah. So this is not a new process, right? We didn’t invent this process.

They’ve been doing it, and they are the ones with seven-day, 40-day turnarounds, paperwork, old technology—you’re seeing all of that. So we are completely disintermediating them. We’re creating a completely new category, where we’re actually differentiating ourselves from them.

We’re kind of coming in and changing the way things are being done in this industry.

Q. That is great to know. So, I think we have covered a lot of ground Siva. Any other closing thoughts or any other information or news that you would like to share with the audience? 

Siva: I know that there is a lot of press around prior authorization. To listeners—especially providers and patients—almost everyone goes through this. Just know that companies like Cohere are now using AI to solve the problem. Relief is on the way.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Scaling With Autonomous AI for Diabetic Retinopathy Screening

Season 6: Episode #165

Podcast with Alvin Liu, M.D., Inaugural Director of AI Innovation Center, Johns Hopkins Medicine

Scaling With Autonomous AI for Diabetic Retinopathy Screening

To receive regular updates 

In this episode, Dr. T.Y. Alvin Liu, Inaugural Director, James P Gills Jr MD and Heather Gills AI Innovation Center at Johns Hopkins Medicine shares his journey in healthcare AI, with a focus on image analysis and real-world applications.

Dr. Liu discusses the FDA-approved autonomous AI system for diabetic retinopathy screening, which enables early detection in primary care settings and improves screening adherence. He outlines successful AI implementations at Johns Hopkins Medicine, including prior authorization pilots using generative AI and the importance of operational understanding in deployment. He also discussed the intersection of value-based medicine and artificial intelligence, and the challenges of implementing successful AI programs. 

At the enterprise level, Dr. Liu emphasizes the need for strong AI governance to assess safety, effectiveness, and ROI. He outlines key challenges for AI startups, especially around reimbursement and regulation, and urges them to pursue sustainable business models. He also suggests closer collaboration among startups, VCs, and integrated health systems to bridge the gap between innovation and real-world adoption, essential for scaling AI responsibly and delivering long-term value in healthcare. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Dr. T. Y. Alvin Liu, the James P. Gills Jr. M.D. and Heather Gills Rising Professor of Artificial Intelligence in Ophthalmology, was born and raised in Hong Kong. He subsequently attended Phillips Exeter Academy, Cornell University (B.A.) and Columbia University (M.D.). He completed his ophthalmology residency and vitreoretinal fellowship training at the Wilmer Eye Institute at Johns Hopkins University (JHU), and was named an “Emerging Vision Scientist” by the National Alliance for Eye and Vision Research in 2020. Currently, he holds dual faculty appointments at the JHU School of Medicine and School of Engineering. He is also the Inaugural Director of the James P. Gills Jr. M.D. and Heather Gills Artificial Intelligence Innovation Center, which is the first dedicated endowed ($10 million) AI center at the JHU School of Medicine.

As an interdisciplinary strategist at the intersection of venture capital, startup companies and health systems, he specializes in the implementation and scaling of healthcare artificial intelligence (AI) technologies in both clinical and operational domains, for example autonomous AI for diabetic retinopathy screening and generative AI for revenue cycle management. He has operational experience in various processes that are critical for AI deployment, including incentive alignment of stakeholders, IT integration, workflow design, key performance indicator establishment, and change management.

In addition to being an advisor/Medical Director for startup companies and a venture partner at a healthcare-focused investment fund, he has also completed executive education coursework at Wharton (venture capital), Harvard (digital transformation in healthcare), and Johns Hopkins (value-based healthcare).

In terms of AI governance, he holds leadership positions on a health system and national level. At Johns Hopkins Medicine, he is a co-chair of the AI and Data Trust Council, a leadership team that oversees all AI initiates across the entire health system in the imaging, clinical and operational domains. On a national level, he is a member of the American Academy of Ophthalmology AI Committee, and represents ophthalmology at the American Medical Association AI Specialty Society Collaborative Meeting.


 Q. Hi Alvin, welcome to The Big Unlock Podcast. It’s a pleasure to have you on board. As you might be aware, this was started by my colleague Paddy Padmanabhan from Damo Consulting, and we’re building upon what he left us as his legacy. I’m Rohit Mahajan, Managing Partner and CEO at BigRio and Damo Consulting, and I’m also the host of The Big Unlock Podcast.

Alvin: Rohit, thank you so much for having me on this podcast. I’m excited about the interesting topics we’ll be chatting about today.
So yes, happy to give you an introduction and some sense of where I came from and what I’m interested in.

My name is Alvin Liu. I was born and raised in Hong Kong. I came to the U.S. as a teenager to attend a boarding school in New Hampshire. After that, I did most of my schooling on the East Coast. I’m a practicing retinal surgeon. I did my ophthalmology residency and retinal fellowship at Johns Hopkins Medicine, and I stayed on as faculty.

I actively practice and take care of patients with a variety of retinal problems. Outside of my clinical work at Hopkins, I’m focused on artificial intelligence in several areas.

Within Johns Hopkins Medicine, I wear several hats. First, I’m the inaugural Director of the Gills AI Center at the Wilmer Eye Institute—this is the first endowed AI center at the Johns Hopkins School of Medicine, made possible by a generous $10 million donation by Dr. Gills.

Second, I’m a clinician-scientist involved in the development of clinical AI tools.

Third, in recent years, my focus has been on the implementation of AI tools for both clinical and operational purposes at the health system level. I’m sure we’ll dive into specific examples later today.

And fourth, I’m involved in AI governance. As you can imagine, there are many developments in AI in healthcare. In response, Johns Hopkins Medicine recently established a leadership team to oversee AI efforts across the entire health system, and I’m part of that team. I’ll be happy to talk about the AI governance work we’re doing at Johns Hopkins.

 Q. That’s amazing, Alvin. I wonder—with so many responsibilities, how do you even find time? Do you sleep at all? 

Alvin: I do sleep and try to get seven to eight hours sleep every day. I think that’s extremely important because, I myself cannot think very well if I don’t get enough sleep. So, I do put a premium on the amounts of sleep that I end up getting.

 Q. That’s amazing. So tell us, Alvin—you studied here on the East Coast and you’re a practicing physician. What attracted you to technology, especially emerging technologies, and when did you get involved with it? Also, talk to us about some of the work you’ve done in this area.

And even before that, if you’d like to talk about the health system itself, the geography, and the kind of patient population it serves, feel free to do that as well.

Alvin: Sure, I can start by talking about how I got involved in AI.
Near the end of my clinical training, around 2017–2018, I first got started with artificial intelligence. That was when a specific kind of AI technique called deep learning really started gaining traction.

Deep learning is the underlying architecture that powers much of what we know as AI today in 2025. It’s especially good at two things: image or video analysis, and more recently, natural language processing through large language models.

Back in 2019, most deep learning applications in healthcare focused on image analysis. As a retina specialist, I’ve always worked closely with images. If you look across medical specialties, radiology and ophthalmology are the most image-intensive, both in research and clinical care.

That’s why, when you look at AI research and real-world implementation today, the two medical fields leading the way—in the U.S. and globally—are radiology and ophthalmology.

What really got me interested in deep learning’s application to ophthalmology, and to medicine more broadly, was a study published by Google a few years ago. They showed you could train an AI model to predict someone’s age, sex, blood pressure, and smoking status just by looking at a retinal photograph.

That’s a superhuman capability—no doctor can do that. That one paper convinced me that AI would change medicine and society as we know it. And that’s something I want to dedicate the rest of my life to.

 Q. That’s amazing. So, tell us a little more, Alvin, about Johns Hopkins as an organization and the kind of patient population you serve. And then we can dive into some of the use cases you’re seeing or currently working on. 

Alvin: I’ll start by giving a sense of what Johns Hopkins Medicine is about, and then we can dive into specific examples.

Johns Hopkins Medicine is headquartered in Baltimore, Maryland. As an integrated health system, we operate six hospitals and around 50 outpatient sites. We serve a wide range of patients, most of whom are urban residents. Over the past several years, we’ve been working on a variety of AI initiatives. I’ll give you two specific examples.

The first is a clinical one—the deployment of autonomous AI for diabetic retinopathy screening, which we started in 2020. This is a significant application. When this technology was first approved by the FDA in 2018, it was the first-ever fully autonomous AI system in any medical field to get FDA approval. So my field, retina, actually made history. A recent study published in the New England Journal of Medicine AI showed that this technology is now the second most widely used clinical AI tool in the U.S. I think it’s a great gateway example to explain the broader medical AI ecosystem.

The idea is simple: everyone with diabetes should get an eye exam once a year. Diabetic retinopathy is the leading cause of blindness in the working-age population globally, and it’s expected to worsen with rising diabetes rates. It’s also well studied—we know that annual screenings, early detection, and timely treatment are effective and cost-efficient in preventing blindness. However, the challenge is that even in the U.S., only about 50% of patients with diabetes undergo these recommended screenings each year. The rate is even lower in many other countries.

Autonomous AI changes that. Traditionally, a primary care doctor would prescribe medication and manage diabetes, but eye screening required a separate appointment with an eye specialist, which creates friction. With autonomous AI, screening can now happen right in the primary care office. Imagine going in for a routine visit—your vitals are checked, medications refilled, and now, photos of your retina are taken. These images are analyzed in real time by an AI model in the cloud. Within a minute, the AI autonomously determines whether or not you have diabetic retinopathy.

If the answer is yes, you’re referred to an ophthalmologist. If no, you’re done with your screening for the year. We started using this at Johns Hopkins in 2020 and reviewed the data to evaluate its impact. The result? Yes, it worked. We saw improved adherence to the annual screening guidelines.

When we looked closer, the greatest improvements were seen among historically underserved groups—African Americans and Medicaid patients. The positive impact was outsized for these communities, and we published our findings in Nature Digital Medicine about a year ago. The second example is operational—using generative AI for revenue cycle management.

For those unfamiliar, revenue cycle management is how health systems like Johns Hopkins get reimbursed for the care we provide. It’s complex and involves many steps and a lot of paperwork. Traditionally, automation efforts have relied on older machine learning approaches like robotic process automation (RPA), which require a lot of rule writing and don’t handle exceptions well. This is where generative AI, particularly large language models, shine. They are adaptive, understand text and unstructured data, and can handle edge cases much better.

We’ve used GenAI specifically for prior authorization. It has significantly reduced the time needed to complete and submit each case, making the process more efficient overall. So, these are two real-life examples—one clinical and one operational—where we’re currently using AI at Johns Hopkins Medicine.

 Q. That’s very interesting. So, I have just some curious questions. Alvin, on the first example I. That you talked about in the primary care physician setting, that a patient can go and get their eyes checked. So, does it need specialized equipment at this time, do you think? At some point in time, it may be that I can just use my iPhone camera and or look into some kind of a kiosk. And, you know, kind of get it done at the airport or, you know, I always look into this when I do the security clearance. 

Alvin: That’s a great question. You’re touching on a really important point—the nuts and bolts of implementation. Implementation is key when it comes to scaling any kind of technology, including AI.

The short answer is yes, it does require some specialized equipment, but these are very common. In short, you need a way to take a picture of the back of the eye, which we call a fundus camera. These are already widely used by ophthalmologists, and there are many different brands and models. So, if you step back, there’s already an existing supply chain and industrial process in place for producing these cameras.

Now, the traditional cameras are desktop-based. They’re not very portable—they’re a bit heavy, and you can’t easily carry them yourself. But their footprint is relatively small—about two feet by two feet—and they can sit on a mobile table. So they’re easily accessible, and the image quality is quite good.

Of course, there’s been work on developing more portable cameras, and many of those already exist. You can even use an adapter with a smartphone to capture retinal images. So the technology is there.

However, in real-world settings, most of the AI models for diabetic retinopathy—especially the ones used in clinical deployment—are designed for use with the more common desktop-based fundus cameras. While they’re larger, they typically deliver better image quality, which is why they’re still preferred.

 Q. And then a curious question on the prior auth side—are you implementing and experimenting with prior auth across the board, or is it for a certain set of disease conditions, CPT codes? And then, is that a software that the team has developed, or is it something you’re using from the outside in? 

Alvin: That’s a great question. So, what you’re getting at is the nuances between the different service lines—who would benefit from prior authorization or not.

Broadly speaking, there are certain fields that require a lot of prior authorization, and that’s how insurance payers do utilization management. And I’m painting with very broad strokes here.

Typically, the service lines or medical specialties that require prior auth tend to give out more expensive treatments—things like infusion medications in oncology or dermatology, or in our case, retina. We do a lot of injections into the eye—what we call intravitreal injections—for diabetes and age-related macular degeneration. These are examples where, because the treatments are expensive, they’re more likely to require prior authorization.

So when we did our pilot at Hopkins, we focused more on those specialties that require a lot of prior auths, versus ones where the care typically just goes straight through without it.

But that’s a great question, and you’re absolutely right—the devil is in the details. Even for a relatively specific step in revenue cycle management like prior auth, designing a pilot that makes sense, that demonstrates ROI, and establishes relevant KPIs—requires a very deep understanding of how medicine works and operates. And not in a vacuum.

 Q. So shifting gears a bit, Alvin – with the macroeconomic factors now impacting the whole ecosystem, including digital health (which is a very large part of the U.S. economy, as we all know) – what are some of the things that you feel are coming in the near future?

Alvin: I’ll answer your question from two opposite ends of the spectrum. First, from the startup angle—because in my role at Hopkins, I end up interacting a lot with startup companies in the AI space. And then I’ll speak from the enterprise perspective.

So on the startup side, I think one of the common mistakes startups make in the healthcare AI space is not considering—or not understanding—the reimbursement issue from day one. And I think that’s the most important thing.

One could argue that healthcare AI is still a very new field, so the payment mechanisms in the market aren’t yet mature enough to handle an influx of new products. It’s a tough situation, honestly, for healthcare AI startups. If you’re on a founding team that doesn’t have a deep understanding of how medicine works, you probably don’t know what a CPT code is, or how that’s how services get paid for. If you want to get a CPT code, very likely—especially if you’re in the AI and medical device space—you fall under the FDA’s purview.

And if you want FDA approval, we’re talking about $3 to $5 million off the bat. One mistake I see is startups being hyper-focused on building the product—both in terms of execution and how they spend their funding—without accounting for or budgeting for that FDA process. And even if you’re lucky enough to get FDA clearance, then you have to think: are there existing CPT codes that will reimburse you for the AI service? Very often, there are not. So then you have to go to the AMA to negotiate a new applicable CPT code.

That process takes a long time. And even if you succeed in getting a new CPT code, there’s no guarantee the payers will reimburse you. And even if they do, the rate might not be financially sustainable.

So from the startup side, you really have to think long and hard about your reimbursement pathway. Of course, there are other ways to get paid—not just through CPT codes—but that requires a deep understanding of healthcare business models. And in some cases, you may need to invent a new one.

Now, on the enterprise side: AI is here to stay. But for health systems, it’s chaotic. We—as an integrated health system—get many, many sales calls from AI companies every day. It’s a crowded, noisy space. That’s why having a robust AI governance structure that looks at multiple aspects—clinical, operational, ethical, financial—is absolutely necessary. And I think Johns Hopkins Medicine is one of the first major integrated health systems to give this serious thought.

It’s still evolving. We’re learning. But building a thoughtful and industry-friendly governance system is critical. And if you zoom out even more—on a very macro level—the billion-dollar question is: how will value-based care and AI come together? These are two very big trends that will intersect soon. What that intersection looks like is going to be very interesting.

 Q. That’s very good insight, Alvin. So could you talk to us about any digital health programs that have been implemented and that you’ve been involved with, which improve access to care—or any other examples you’d like to share from the digital health side? 

Alvin: The example I would give is the autonomous AI for diabetic retinopathy screening program. Yeah, that’s a good example. We already talked a little bit about it. What we learned is that, again, like 80% of a successful program is all about implementation and how you execute things.

So, for example, even if you have a successful screening program at the level of primary care, you still have to figure out how to get the patients who screen positive to ophthalmologists. That’s a different line of work.

You can extend this analogy to other areas as well—for example, in omics. Just to set the stage, omics is a relatively new field that connects biomarkers found in the eye—mostly retinal biomarkers—with systemic health conditions. I’ll give you a couple of examples. Right now, we can already use retinal images paired with AI to predict someone’s future cardiovascular risk, risk of kidney damage, or even dementia.

So, I think diabetic retinopathy is just an early example. We’re going to see an explosion in the adoption of omics. But the question is: even if you have an AI-based omics screening program in a community or primary care setting, and you identify patients at risk for various systemic conditions like Alzheimer’s or cardiovascular disease—what do you do next?

How do you set up a workflow to get these people to the subspecialists they need to see downstream? That’s still in the works. It’s very fluid. But I think that kind of thinking—being able to implement and execute things efficiently at scale—is going to determine the success of a lot of AI programs, especially when it comes to AI in omics.

 Q. Yes, that’s amazing. So, Alvin, we talked about governance a bit. How do you structure prioritization and funding, and what kind of operating models do you look at? 

Alvin: Sure. I’m happy to talk about that. I’ll take a step back and give you a brief background on how this all came about.

Back in 2024, the executive leadership at Johns Hopkins Medicine started a task force to develop an implementation strategy that ensures Hopkins becomes a global leader in the responsible use of AI.

One of the key tenets the task force identified was that they wanted this to be a clinically led responsible AI program—meaning physicians like myself would and should play a major role.

The task force then identified seven core principles that are critical for responsible AI: fairness, transparency, accountability, ethical data use, safety, evidence-based effectiveness, and so on.

From these, we identified several implementation plans. A key one was to establish a governance process and framework that would integrate with existing governance structures. As a result, an AI oversight team was created. It’s an eight-person leadership team drawn from across the health system. I’m one of the eight, and we have purview over all things AI-related across clinical, imaging, and operational domains.

In a nutshell, what we’ve developed is a standardized framework for how AI vendors should interact with Johns Hopkins Medicine. So, for example, if you have a clinical AI product and want to engage with us, there’s a standardized intake process. First, you need to find an internal partner at Johns Hopkins who will advocate for you.

We then have standardized questionnaires—what is the tool used for? Do you have data cards? Model cards? What’s the expected ROI? How do you demonstrate it’s safe? And so on.

Based on the nature of the tool—whether it’s clinical, operational, or imaging—the application gets routed to different sub-teams. Then there’s an internal review committee that dives deep into the responses. We grade them, bring them back to the committee, debate, and often go back to the vendors with follow-up questions.

Ultimately, the committee does an up-or-down vote based on a variety of criteria and decides whether the tool can be implemented at scale across the enterprise—or not, and why.

 Q. That’s very robust process Alvin. Thank you for sharing such good examples, thoughts and advice so far. Any final closing comments? I think we are coming to our end of our conversation. Any other things that you would like to bring up? Any announcements, news items? Or anything else that you would like to share that’s upcoming on your horizon?

Alvin: What I’d say is that, at a high level, most people agree that AI is going to change medicine—and society—as we know it. The train has left the station. It’s no longer a question of whether we’ll adopt AI, but what the future will actually look like.

When it comes to healthcare specifically, it’s one of the most heavily regulated industries—and also one of the most personal. At the end of the day, we’re in the business of taking care of people and reducing suffering, and there’s a deeply human, emotional component to that.

I do believe that, for the good of humanity, we need much more collaboration in this space. And in particular, I see venture capital and startups as major engines of innovation.

What’s been missing—but is starting to improve—is a strong connection between the VC/startup world and integrated health systems. I think that relationship needs to get better. In the U.S., integrated health systems deliver the majority of care. So whether startups like it or not, their products will ultimately have to go through these enterprises.

That said, health systems don’t move as quickly as the tech industry. And that’s understandable—but I also think there’s room for improvement, particularly in how quickly decisions are made. Technology is evolving at an exponential rate, and AI is no exception. Things move fast—and for good reason.

So, there’s work to be done on both sides. I’m hopeful that we’ll see much stronger and closer collaboration between startups and health systems in the near future. If that happens, I think a lot of good will come out of it.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

We Believe in Provider-led AI Where Clinicians Have the Final Say

Season 6: Episode #164

Podcast with Patrick Mobley, Co-Founder and CEO, Vivid Health

We Believe in Provider-led AI Where Clinicians Have the Final Say

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In this episode, Patrick Mobley, Co-Founder and CEO at Vivid Health shares how his personal background and professional journey inspired him to launch a platform that improves clinical workflows using generative AI.

Built in collaboration with Redesign Health, Vivid Health’s platform is designed to automate time-consuming, manual processes, such as patient outreach, assessments, care planning, and follow-ups—freeing nurses and care teams to focus on providing care. Patrick highlights their “provider-led AI” approach, where providers retain final control over AI-generated outputs. The platform supports over 100 conditions across 16 specialties and is being adopted in primary care, home health, and hospice settings. It reduces documentation time by over 50% and eliminates outreach labor in chronic care management workflows.

Patrick also emphasizes the platform’s value in scaling care, improving patient engagement, and supporting revenue generation, while offering deeper, more honest insights through automated, holistic patient assessments. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Patrick is Founder and CEO of Vivid Health, a generative AI care management platform serving risk-bearing providers, payers, and post-acute facilities. He previously served as President of the Mid-Atlantic for Bright Health, where he led one of the nation's largest exchange plans, growing membership by over 500% within two years.

Prior to Bright, Patrick led Aledade’s largest national market in North Carolina, guiding independent providers in adopting value-based care strategies and expanding the local value-based care network by over 200% within 10 months. His executive experience also includes several senior roles at Evolent Health: as Market President for Virginia, he managed one of the nation's largest full-risk ACOs; as Managing Director for Payer Partnerships, he oversaw the company's entire value-based care portfolio; and as Senior Director for Business Innovations, he led new market implementations nationwide. Patrick's career began in consulting, working with Deloitte and Grant Thornton, among other firms. He earned a degree in Psychology with a minor in Public Policy from the University of North Carolina at Chapel Hill, and holds an MBA from East Carolina University.


Q. Hi Patrick, welcome to the Big Unlock podcast. Great to have you with us today. I’m Rohit Mahajan, Managing Partner and CEO of BigRio and Damo Consulting. The Big Unlock podcast was started by Paddy Padmanabhan, founder of Damo Consulting, and it’s been a successful series with many healthcare leaders. Great to have you here.

Would you like to introduce yourself to the audience? 

Patrick:  Sure. I’m Patrick Mobley, CEO and founder of Vivid Health. A bit about my background—I’m speaking to you today from Raleigh, North Carolina. I grew up around healthcare; my dad was a physician. I eventually found my way into the startup world. I was an early employee at a company called Evolent Health, where I did a bit of everything. I started on the clinical side, ran their Virginia market, and oversaw value-based care operations.

Then I moved to Aledade, where we aggregated independent providers into shared savings arrangements. We grew from about 20 practices to 220 while I was there. Next, I joined Bright Health and ran a large health plan in the Mid-Atlantic. Across all three companies, I saw what high growth looks like—but I always wanted to build something myself.

Eventually, I connected with the leadership at Redesign Health. I had hired a company that spun out of them. For those who don’t know, Redesign is a venture studio based in New York, backed by General Catalyst, UPMC, CVS, and Aetna, among others. We came up with the idea for Vivid, which really reflects a lot of that experience. I know we’ll get into the details, so I won’t spoil it all now—but it’s really focused on making clinicians’ lives better. 

Q. That’s really interesting, Patrick. You’ve had such a deep career in healthcare. What was the early catalyst that set you on this path?

Patrick: As I mentioned, I grew up around my dad’s clinic. It was a very familiar environment.
I saw how hard he worked—the long hours, the behind-the-scenes frustration with paperwork and administrative work. It was inspiring to watch, and it made me want to solve some of those pain points. Thinking I could build something that might help with the things that gave him headaches was definitely exciting. 

Q. That is awesome to know. So, you mentioned Vivid already and it came out redesign. So Patrick, please tell us more that. What is your thesis at Vivid Healthcare and and what kind of problems are you solving and what are you working on?

Patrick: In my prior roles before Vivid, I worked closely with nurses or had them report to me. What stood out was how much time it took to call a patient, assess them, build a care plan, and follow up. These are four essential steps in any risk-bearing organization looking to manage cost, high-risk individuals, close care gaps, and improve risk adjustment. I kept thinking—how do we leave the nurses with nothing left to do but provide care? And when I say “nurses,” I also mean LCSWs, community health workers, the whole care team.

So, in partnership with Redesign, we started exploring what generative AI could do—specifically, how we could automate tactical workflows already used in care organizations. That’s exactly what we’ve built: from intake and referral, where an AI agent can call, text, or email a patient, to assessment, care plan generation via a large language model, clinician approval, and automated follow-ups. Whether the patient is with the practice for a day or six months, our platform supports it all.

Q. That’s impressive. What makes the platform so unique? You were also one of the earlier adopters of GenAI in clinical workflows. Was it hard to incorporate? And what results are you seeing now? 

Patrick: It definitely wasn’t easy—but we had great partners, like your team at BigRio, to help build it out. We focused on covering a wide range of specialties and conditions. For nurses, it’s about understanding both mental and physical health needs, gathering that data, and turning it into a care plan—while always keeping the provider in control.

In fact, we actually own the trademark for “Provider-Led AI.” We strongly believe that no matter how helpful AI is, the final say should always rest with the clinician. Our platform lets AI agents handle tasks like calling patients, enrolling them in chronic care management, or conducting assessments like OASIS in home health. It builds care plans and allows nurses to focus on care coordination.

One of the most important aspects was making sure we could scale. If we were effective at engaging, assessing, and managing patients up front, then scaling the backend workload was critical. We wanted to amplify our nurses and care teams—individually—but also make sure they weren’t overwhelmed. That’s why we designed the platform to automate follow-ups. The agent can call, text, or email patients. Nurses don’t need to do anything manually. They simply turn on the platform, see patient stratification, view notes from calls, and take action from there. It delivers scale and reach—whether you’re a risk-bearing or home health organization—that you just can’t achieve with any other platform.

Q. So, is that where the positioning of the platform is also Patrick? Tell us a little bit more about who are the kind of potential customers or clients or users of the software platform.

Patrick: Yes. There are a few distinct markets, though I often describe our platform as the perfect puzzle piece for any organization.

One key market is the primary care space. It’s ideal for risk-bearing organizations, but even those that aren’t can still use it to deliver extra care and generate additional revenue.
We can deploy our AI agent to enroll patients in chronic care management, conduct assessments, and complete all required documentation for chronic care, annual wellness visits, and transitional care management. We’re seeing a 100% reduction in outreach specialist labor using our voice AI tool and over 50% cost reduction compared to competitors.

We also target post-acute care—specifically home health and hospice. These settings have some of the most burdensome documentation requirements. In home health, for instance, the OASIS form is 27 pages with 200+ questions. Nurses typically can only see two patients a day because of this.

We’ve automated that entire process. When the nurse enters the home, the OASIS answers are already received, the care plan is generated, and the visit can focus on actual care—not paperwork. We’re seeing over 50% reduction in documentation time, which directly impacts revenue. If a nurse can see even one more patient per day, that’s a significant gain.

Hospice is also going through a big shift to a form called HOPE, which is like a shorter version of OASIS. We’re applying the same technology there and expect similar results.

We currently cover 100 conditions across 16 specialties. That’s generated interest from palliative care providers, non-skilled nursing organizations, and even some specialty groups. Once they see the platform in action, it really resonates. We’re proud of what we’ve built.

Q. That’s amazing, Patrick. And I know you’ve built a robust chronic care management capability across many disease conditions. You also mentioned a bunch of surveys—that’s your proprietary IP, right? So, that is what you built early on the core of the system. So, could you describe that a little bit more in detail on how it adds value and what it actually does?

Patrick: Yes—and there’s a bit of a story there. Many organizations, rightfully, focus on five big conditions like CHF, COPD, diabetes, depression, etc. But I always felt that if a patient has COPD and also a kidney disorder, that second condition could significantly affect their overall health—physically and mentally.

So, we designed our system to evaluate patients across a broad set of conditions, not just a narrow few. We also wanted our surveys to assess both mental and physical health. So we ask questions like, “Do you have chest pain or swelling?” but also, “Do you have anxiety about paying for your meds?” or “Do you have transportation and social support?”

This creates a holistic view of the patient. The feedback we’ve received is that when patients interact with a clinician directly, they may feel pressure to answer a certain way. But when we deliver the assessments through text, email, or voice, patients respond more honestly. Nurses tell us the responses they get are clearer, more detailed, and more accurate than before. That’s been very cool to see.

Q. So when you are thinking of this in a larger setting, Patrick, obviously you might need to think about how it integrates with the systems organizations might already have in place. So what is your approach to that? How do you make it easy for your customers to use it?

Patrick: Yeah, I think there are three paths there. One, just straight out of the box, the platform works really well as a standalone. It can do everything we’ve talked about so far—it does really well.

Second part of that answer is we use FHIR server—that creates a data standard for us to push and pull information from and integrate, frankly, with most EMRs. So we’re fully capable of integrating with just about every EMR in the market.

The third, and it’s the most interesting, is we partnered with an organization called NO2, which is part of something called a QHIN. And I know I’m getting kind of technical, but QHIN is a Qualified Health Information Network. What that is, is an interoperability layer to our platform that allows us to push and pull data from just about every EMR instance in the country.

For example, every single hospital in the states of Washington and Oregon is on this QHIN. So today, while we may not be directly integrated into OHSU in Portland, we can access their EMR—we can push and pull data, we can make requests. And I really think, like bigger picture beyond Vivid, that capability is going to be table stakes for any organization entering the digital health space.

Q. That is great to know. So tell us where you think the future is, Patrick, and what are some of the early findings that you have from your client implementations, and where are you headed in the next few weeks or months? 

Patrick: Well, hopefully a lot of growth. We’re certainly seeing a lot of interest. There’s no limit of folks that want to talk to us, engage with us, and understand what the platform does.

I think what we’ve seen—and it’s been kind of entertaining to watch—is when we go through our demos and what the platform can do on the voice side, we’ll have them call the agent—her name is Sage—and just the faces light up. Their creative juices start flowing. They start thinking, what are the many different places they can deploy this agent?

You’ve gotta think of her as like an employee that doesn’t get tired, that can work 24 hours a day, that you only have to train once. And it’s incredibly powerful. So I think all phone calls that don’t require clinical decision-making will ultimately be done by agents like this long term—and across specialties, it doesn’t really matter.

Then the third thing—more going way out in the future—I think that at least within our platform, we’ll start to deploy different types of agents. So we talked about voice agent, which is one type. Another is one that will take all the data we’ve acquired—and maybe we’re not directly integrated with the EMR—but we are using the agent to go into that EMR and deploy data into specific sections.

I was at a conference last week and part of the conversation was, does the EMR just become the file cabinet for everything, but all the action happens in applications like Vivid? The idea is that because of these QHINs that I referenced earlier, it’s going to allow pushing and pulling data, and the agents can take it and put it into the specific spots it needs to be.

So maybe the EMR stays the source of truth or system of record, but the actual technical capabilities and advancement—and frankly, the efficiencies that AI will bring—will live in a layer above that. And that’s where the clinician does a lot of their work. I could see that definitely happening, because I think agents will be able to operate everyone’s computer at some point.

Q. Yeah, that’s true. Patrick, just shifting gears a bit—because you mentioned value-based care, and that is something you’ve been very closely associated with—what are the macroeconomic or other trends that you’re seeing, whether it’s value-based care becoming more prevalent or anything else coming our way?

Patrick: Yeah, so I think, having lived in that world for many years, I don’t think it’s going to entirely go away. We’re not at 80% market saturation with primary care being in a risk-based arrangement. I think the MSSP numbers are around 40 to 45%, somewhere in that range.

What’s interesting is, pre-AI, the way organizations worked with independent primary care—or even a health system—was that you’d deploy a lot of nurses and staff to find the sickest of the sick, manage them well, try to bend the cost curve, and then make money based on how much you saved.

A lot of those organizations had deal terms where, for every dollar, 50 cents went to the company and 50 cents back to the provider. I think the revenue opportunity for the provider is going to go up because the cost of providing those services is going to go way down, thanks to AI.

So instead of deploying an army of people into an ACO, the agent can make all the same phone calls, do all the same engagement, at a fraction of the cost. And now it’s going to look a lot more appealing to a primary care doctor who, instead of making 50 cents on the dollar, can make 80 cents.

As those models mature and the technology merges with them, it may accelerate—but we’ll see. There are contingencies, but there’s definitely a path that could be really interesting.

Q. Right. Any other changes that you’re seeing that might impact the business model—or anything else coming up in the future—that you’d like to share as part of your closing remarks? We’re getting to the end of the podcast here. 

Patrick: I think it’ll be interesting to see whether it’s federal or state governments that ultimately dictate individual AI regulations in healthcare. You’d prefer it to be more federal than state, or else you end up with 50 sets of rules that every company has to manage.

Had this discussion last week—you want a standard. You want everyone playing by the same rules. And if it doesn’t happen fast enough on the federal side, states are going to figure it out themselves, which could lead to unintended consequences for organizations wanting to operate in multiple states.

That’s not just true for us—that’s true for OpenAI too, who may have different rules in 50 different states. So, having a set of standards and regulations to help manage what’s coming—not just for Vivid, but AI in general—is probably something we should all be keeping an eye on.

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

From Automation to Autonomy: Agentic AI Is Healthcare’s Next Frontier

Season 6: Episode #163

Podcast with Shekar Ramanathan, Executive Director of Digital Transformation, Atlantic Health System

From Automation to Autonomy: Agentic AI Is Healthcare’s Next Frontier

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In this episode, Shekar Ramanathan, Executive Director of Digital Transformation at Atlantic Health System shares how the organization is evolving from traditional automation to a future shaped by agentic AI. He shares Atlantic Health’s journey from pilot projects to scalable AI implementations, highlighting real-world use cases such as ambient scribing, intelligent message routing, and virtual medical assistants for patient engagement. 

Shekar outlines how Atlantic leverages generative AI to tackle both clinical and operational challenges, guided by a strategy that aligns AI initiatives with organizational goals. He emphasizes working backwards from the outcomes, integrating AI into specific workflows, and the need for strong governance frameworks. He also shares insights on Atlantic’s AI maturity model, challenges in scaling, cost containment, prompt engineering, and the critical role of education and cultural change. 

Looking ahead, Shekar sees agentic AI as a transformative force—one that reduces administrative burden and unlocks new levels of autonomy in care delivery. He also reflects on the rising importance of Chief AI Officers in driving responsible and effective AI strategy across health systems. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Shekar Ramanathan has over 20 years of progressive leadership experience in health information technology and is a nationally recognized speaker on enhancing patient and provider experiences through digital transformation. He has been honored on various well recognized lists, including Becker’s Healthcare Up and Comers in Health IT, and was recently recognized as an NJBIZ Leaders in Digital Technology honoree for his contributions to the field.

Currently serving as the Executive Director of Digital Transformation for Atlantic Health System, he is responsible for developing the digital strategic vision and designing holistic solutions that enhance patient, clinical, and operational experiences. His data-centric approach to real-time decision-making and adoption of cutting-edge technologies has positioned the organization as a healthcare pioneer. Additionally, he has spearheaded the creation of new business opportunities by leveraging emergent technologies such as AI, machine learning, and predictive analytics.

He holds a Bachelor's degree in Information Systems from the University of Washington, graduate education in Medical Informatics and Healthcare Management from Oregon Health & Science University, and an MBA from The Ohio State University. He also holds numerous certifications, including Certified Healthcare CIO (CHCIO), Certified Digital Health – Executive (CDH-E), and Certified Professional in Healthcare Information & Management Systems (CPHIMS).


Ritu: Hi Shekar, welcome to The Big Unlock podcast. It’s really nice to have you on the show. We’re now in our sixth season, with over 150 episodes and a great listener base. We’re excited to have you here and look forward to a lively discussion.

I’m Ritu M. Uberoy, Managing Partner at BigRio and Damo Consulting, and also a co-host of The Big Unlock podcast. I’d like Rohit to say a few words before we hand it over to you.

Rohit: Short intro from my side as well, Shekar. I’m Rohit Mahajan, CEO and Managing Partner at BigRio and Damo Consulting, based in Boston. As I mentioned, we’re very happy to have you on the podcast.

Shekar: It’s a pleasure to be here, and I’m looking forward to a great conversation with both of you.

I’m Shekar Ramanathan, Executive Director of Digital Transformation at Atlantic Health System. We’re a seven-hospital—soon to be eight—health system based in New Jersey, with over 20,000 employees and about half a million patients in our ACO.

We’re a fairly large organization, and I’m responsible for the integration of digital, AI, and data—essentially, using technology to solve business and clinical problems.

We’re really focused on working outcomes backward: identifying what we want to accomplish, the metrics we aim to achieve, and then developing solutions to meet those needs.

Ritu: Great. Great. We all know generative AI is the buzzword right now. I just attended two conferences—HIMSS and Human X—both heavily focused on AI, generative AI, and now the latest: agentic AI.

We’d love to hear your thoughts on these technologies, your AI maturity model at Atlantic Health, and where you feel the organization stands in terms of AI maturity. Also, tell us about some initiatives you’ve led or are currently working on.

Shekar:  Sure. I don’t think I’ve been at a conference or had a talk in the past two years that hasn’t been about AI. Even if it starts with something else, it ends with AI. It’s definitely the hot topic no matter where you go.

For us, it’s very much focused on the “what are we still like…” I think our strategy hasn’t changed in terms of what we’re trying to do from a digital or organizational perspective. What we’re really trying to do is see how we align that with the new capabilities that are emerging—continuing the same business strategy, which is always somewhat challenging because people keep asking, “What is our AI strategy?”

I used to say our AI strategy is our business strategy—it’s not any different. But I’ve somewhat changed that over the past two years. Now, our AI strategy is really about building the framework. It’s about enabling the business and understanding where the technology is going so we can be in a position to fully leverage it.

That means setting up the right governance and the right processes to monitor AI—to ensure it’s the right solution and at the right cost. I think that’s been a challenge for many organizations. You see a lot of piloting—we started there too, with plenty of pilots. But scalability becomes a challenge.

Then comes the question: who are the right people to use these tools? How do we extract value and not just get excited by the art of the possible?

We’ve done a lot of what other health systems are doing—ambient voice, note summarization, routing of messages, and so on. But we’ve also done some novel things, like focusing on a virtual MA where we use a quasi-agentic approach. Not fully agentic, but using some of those tools for outreach, patient communication, helping manage care—with escalation to a clinician or care provider whenever necessary.

We’ve seen a lot of success. At the same time, we know things are changing rapidly. That’s probably one of the biggest challenges—not just for us, but for healthcare in general. We’re used to a fairly slow process—just selecting a vendor, signing a contract, going through implementation—it’s usually a long timeline.

Now, by the time you select a vendor, the next one is already out, doing it better. So how do we shift to being truly agile in our thinking? Solving problems in smaller pieces, being more iterative—those have been some of our key focus areas and challenges.

Ritu: Great answer, Shekar. It’s amazing that you mentioned the top three use cases—ambient, scribing, and message in boxing. You mentioned that going from pilot to scalability is a challenge. Could you pick one of these initiatives and talk a bit more about your experience—specifically, the timeline and what that looked like?

To give some context, I attended a talk at HIMSS about innovation using GenAI, and one of the takeaways was that culture can be both an enabler and a barrier. You have to be open-minded and ready for these accelerated timelines, but if there isn’t buy-in across the organization, change becomes difficult. Would love to hear your thoughts on that.

Shekar: Absolutely. I think one of the key things is that people often start by piloting with a highly engaged, super excited group—folks who really want to leverage the technology. They get great results in that small setting. But when it’s time to scale, it becomes difficult to replicate the same level of adoption, utilization, and value.

We’ve had more success when we focus on narrow workflows—being very intentional about what problem we’re trying to solve. That allows us to have the bandwidth to do proper education, integrate the technology into the workflow, and not just introduce a tool that people are playing with.

With a lot of the GenAI tools, what we’ve seen is a burst of initial excitement—people want to try it, see what it can do, maybe generate a song about COPD, and that’s great. But then reality kicks in. When people are back to caring for patients, they ask: Is this actually saving me time? Do I know how to write a good prompt? Do I understand when it’s useful—or not?

We’ve had more benefit by being very prescriptive: “Here’s the use case, here’s the prompt, here’s the button to click.” That helps users adopt the tool more effectively and ensures they see real value.

It also helps with cost control. These tools can get expensive as they scale, much like how cloud costs were a challenge to predict a few years ago—but AI takes that challenge to another level. So we want to manage rollout carefully, ensure users understand the benefits, and then scale in a controlled, thoughtful way.

Ritu:  Okay. Thank you. Next, we would like to talk about the role of a Chief AI officer and if Atlantic Health has a Chief AI officer, and what do you think would be the pros and cons of, you know, that role and what are your viewpoints about that role?

Shekar:  So, we don’t have a Chief AI Officer per se. We have a lot of people who kind of wear the Chief AI Officer hat—myself included—where part of my role is to drive what our AI strategy is. And that means different things to different people, right?

For us, it’s really about how we lay the infrastructure so we can support the different ideas and initiatives that are coming in. It’s also about identifying what’s truly different between an AI project versus a digital project or a regular technology project—what do we need to think about differently?

Then, depending on whether it’s a business use case or a clinical use case, we need to make sure we’re bringing in the right stakeholders. Especially on the clinical end, we need to have the right clinicians involved and really understand the potential impact—and make sure we have the right processes around that.

So it ends up being a group effort. I definitely see the role evolving, but the question is whether it becomes a purely dedicated position or if it stays tied into roles like data leadership or digital transformation. I think it really depends on the organization—what makes sense for them, and the size and scale of their AI ambitions.

That said, I do think we’re going to see a lot more Chief AI Officers emerge, especially as the space grows, the opportunities expand, and there’s a greater need for structure and oversight.

Ritu:  Yeah. What we’ve seen with other folks we’ve been talking to is that the real need for a Chief AI Officer, like you said, is around strategy. Multiple people can wear those hats and do the work, but the real need they felt was around governance, ethics, bias, and some of the other thorny problems that crop up.

Would you like to talk about any challenges you’ve faced—primarily in terms of AI implementation—like hallucination, bias, or data integrity? And how you’ve overcome those challenges?

Shekar:  Yeah, and I think one of the biggest challenges is really understanding what a lot of these vendors are doing, especially given the pace at which innovation is happening. And then there’s the challenge around black box AI, right? I mean, that’s the so-called “vendor secret sauce.”

But at the same time—are they really doing something truly innovative? Are they actually getting results? How is it working? Do we know what data they trained it on? Patients in a rural area may be very different from those in an urban area. Or maybe the model was only trained on adults and not pediatric patients. There are so many variables that can introduce bias.

There are also a lot of things that can make a model either work for you or not. So how do you really evaluate that? Right now, a lot of these companies are coming to us without the level of research and documentation we’re used to—things like clear evidence of efficacy or quality outcomes.

It’s sometimes hard to get that information, because this is a new, shiny object and people are excited about the art of the possible. That’s especially challenging for us on the operational side. People come in with a great idea, and they’re promised big results that maybe they don’t fully understand.

It’s like—someone says this tool is 99% accurate. But then, when you look at the positive predictive rate, you realize that nine out of ten times, it throws a false positive. So now you’re getting ten alerts for every one useful one.

Is that really helpful? Sure, it’s 99% accurate—but it shows up all the time, and that affects how people experience it. So we have to interpret that correctly and make sure the business is fully aware of what the actual experience will be—before we sign a contract, implement the tool, and then find out later that it doesn’t meet expectations.

Rohit:  Shekar, I’m very interested about your journey in healthcare so far. The audience always likes to know what got you started, what interests you. What are you thinking about the future as well? So if you can share with us what motivated you to take on this role and how you walked into the healthcare industry segment, and where are you headed?

Shekar:  It would be great. Yeah, no, absolutely. I’ve always been in the healthcare technology space. I went to grad school for medical informatics—back when nobody really knew what that meant. And now it feels like everything is kind of coming together.

I started more on the development and consulting side, working with a number of state governments to develop syndromic surveillance systems and similar initiatives. I also did a lot of research around patient experience during grad school.

Eventually, I ended up at Epic and spent some time there. That gave me a lot of exposure to electronic health records and large health systems. After that, I worked across several large healthcare systems—BayCare Clinic, Kettering Health Network, Wake Forest Baptist Health—and eventually landed here at Atlantic Health System.

Over time, I’ve been focused on clinical applications, digital transformation, generating value from data, and process optimization. And now I’m at a point where I can pull all those different pieces together and apply them more broadly.

I’m really excited about the potential of AI right now. I’ve been talking about the future of healthcare technology for a long time—what we could do with EHRs, how to collect and use data—and now it feels like we’re finally at a tipping point. We’ve spent years burdening our clinicians with documentation, all with the hope that it would one day lead to better care, and I think AI is finally enabling that transformation.

That’s why there’s so much excitement in the space. People are energized—maybe even tripping over themselves a bit—trying to figure out the right solutions. I share in that excitement, but I also want to make sure we do it right. We’ve moved at a glacial pace for a while, and now we’re ready to sprint—but we need to do it ethically and consciously, always focused on outcomes.

I feel really fortunate to be at this point—where everything in my background is converging, and I get to be part of pushing healthcare forward.

Rohit:  Absolutely. I’ll add one more thing here, Shekar—I think you’re right we are at an inflection point. I completely agree with you there. A lot of changes are coming at us fast, and we have to adapt and adopt the technologies that are actually useful.

From a patient perspective—since you mentioned Atlantic Health System is based in New Jersey and you serve around half a million patients—can you tell us more about that geography? Is your patient population very diverse? And is there anything you’d like to share about patient engagement?

Shekar:  Yeah, absolutely. So, we’re primarily based in New Jersey, with a bit of presence in New York and Pennsylvania, but mainly focused in northern and central New Jersey. We have 500,000 patients in the ACO, and even more overall.

New Jersey is very diverse, and that diversity really comes into play when we start talking about things like health equity and digital engagement. One of the challenges is figuring out how to reach patients with varying levels of digital literacy.

Interestingly, the patients who could benefit the most from digital tools often face the most barriers to accessing care in general. So, the question becomes: how do we make it easy and accessible for everyone? There’s a portion of the population that will be really excited that there’s an app for everything, but the ones who really need it may not be thinking in those terms. So, it’s about how we reach out, educate them, and truly enable them to be partners in their own care.

Ritu:  Yeah, I think we’re almost at time. Shekar, would you like to share any closing thoughts? It’s been a really engaging discussion. Maybe you could tell us what you see as the top three future trends with generative AI?

Shekar:  I think the next big thing’s gonna be agentic AI. It’s the next evolution as things become more and more “autonomous.” I think we’re gonna see a lot of kind of a hybrid, kind of a mix of agent traditional generative AI solutions.

I think a lot of this comes down to how do we start removing a lot of kind of that burden of healthcare. We’ve spent a lot of time asking providers to do more and more, and there’s where people are excited is that, maybe more of that can get offloaded so clinicians can really focus on direct patient care and a lot of those other things that may be more administrative or tangential.

That’s really where I think we’re gonna see a lot of technology that’s going to be able to kind of help solve some of those problems. 

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.

About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Hosts

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

Beyond the EHR: Advancing Patient Care with AI and Data Strategies

Season 6: Episode #162

Podcast with Priti Patel, MD, VP and Chief Medical Information Officer, John Muir Health

Beyond the EHR: Advancing Patient Care with AI and Data Strategies

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In this episode, Priti Patel, MD, VP and Chief Medical Information Officer at John Muir Health shares her journey from family physician to CMIO, offering insights into her 23-year tenure and the evolution of clinical informatics. She also talks about key challenges such as change management, the integration of new tools like predictive analytics, and streamlining prior authorization.

Dr. Patel discusses the growing role of informatics in healthcare and how collaboration across clinical and IT teams has driven innovation. One of the key highlights at John Muir Health, a community-based health system, is the early adoption of ambient AI technology for clinical documentation, leading to:

  • reduced cognitive load,
  • time savings of up to 30 minutes per note,
  • and enhanced provider-patient interactions.

She also emphasizes the critical role of seamless EHR integration in driving adoption, with over 60% of providers now using the tool regularly.

Dr. Patel also outlines the organization’s enterprise-wide data strategy, including a robust data literacy initiative that’s empowering staff at all levels, starting with the C-suite, to make data-driven decisions and improve care quality and operational outcomes. She underscores that aligning digital strategies with organizational priorities—while focusing on improving the clinician and patient experience—is central to sustainable transformation. Take a listen.

Show Notes

01:14What interests you in the healthcare industry segment to become the CIO of a hospital system?
02:47How long have you been in the leadership position at UMC, where is it located, and what kind of population does it serve?
03:35You have done a lot of work from technology perspective to support the business needs of the hospital. You've done over 200 applications and transformed the EMR system. Would you like to share with the audience the thought process that drove those changes and what were some of those changes?
07:47What do you think about your digital transformation efforts? If you could describe a few of them which have had impact on the patient population.
08:30Please describe in your own, you know, way that what is digital transformation for provider systems such as yours? Where do you see it going? Some of the challenges that you might have faced and how did it actually end up impacting patients?
11:24 How did you manage to change the mindset of the people? How did they manage to change themselves? To adapt to this new world where technology, especially with AI and GenAI and other new technologies which are coming our way, how do you change mindsets and change behaviors and change culture over there?
13:00Would you like to provide one example of how the technologies which you were implementing, and you continue to be implementing in your hospital system are accessible and usable by a variety of users, including within the hospital and outside the hospital.
16:28How do you innovate? Do you involve external parties? Do you have some kind of a, you know, innovation focus department? Or is it part and parcel of everybody's, you know, kind of like daily life?
19:24What are your thoughts on new technologies, especially Gen AI? Have you been experimenting with any predictive analytics or large language models? What would be your advice or thoughts to any other healthcare leaders on how to go about this journey of exploration?
22:15Standing here now and looking back, if you were able to go back and change one or two things, what would you like to do differently or have done differently?

Video Podcast and Extracts

About Our Guest

Priti Patel is the Chief Medical Information Officer at a John Muir Health, where she leads efforts to thoughtfully integrate emerging technologies into clinical practice. She has been at the forefront of AI adoption in healthcare, guiding her organization to become an early adopter of Ambient AI scribes in July 2023. This pioneering work has helped reduce provider documentation burden, improve clinician satisfaction, and enhance the overall patient experience through seamless integration of AI into EHR workflows.

In addition to her work in AI, Dr. Patel has developed and led a system-wide data strategy focused on advancing data literacy and cultivating a data-driven culture. Through education, engagement, and strong governance, she has helped empower clinical and operational leaders to leverage data more effectively in decision-making and performance improvement.

Dr. Patel is passionate about bridging the gap between technology and clinical care, ensuring innovation supports the needs of patients, providers, and the broader health system.


Q: Hi Priti, this is Rohit Mahajan. Thank you for joining us on The Big Unlock podcast. We are in season 6. The audience is diverse and broad. So, we are looking forward to an exciting interaction today with you, and with that, would you like to introduce yourself?

Priti: Sure. Well, that is amazing, the number of podcasts you have done. I enjoyed listening to some of your former guests. Son and I appreciate the opportunity to be here. So, my name is Priti Patel. I am a family physician and clinical informaticist.

I am serving as the Chief Medical Information Officer at John Muir Health, where I have been for 23 years now. John Muir Health is a community-based health system located in The San Francisco Bay area. We serve Contra Costa County and some of the surrounding areas. We have a two-hospital system, one behavioral health center, and over a thousand providers.

When I started 23 years ago, I started off as a primary care physician and quickly got into the administrative side of medicine and medical directorships somewhere along the journey. The electronic health record came to be, and so I started off as a super user, and then one thing led to the other. I was very involved with our enterprise-wide implementation of Epic, so that was in 2012. From there, I just continued to keep doing the same and took the position of associate CMIO, and then for the past three years, I’ve been in the CMIO role, so I am very fortunate that I get to spend most of my days at the intersection of clinical care and technology.

Q: That’s amazing, Priti. You spend so much time in this field. Tell us a little bit about how you work with your colleagues. If you are the CMIO, then you might have other colleagues in your organization who are also involved with technology. So, how do you work together as a team, and what do you think is the evolving role of the CMIO in health IT and its adoption?

Priti: I am fortunate that I have had two other CMIOs before me, and so they were critical in laying the foundation for our informatics structure. Our first CMIO was responsible for our EHR implementation. The second came in and really established a lot of committees, the governance, structures really helped optimize those, and through that entire journey we continue to grow year by year. Just the number of clinicians and physicians that have been involved in informatics is really astounding. When I started, no one even knew what the term informatics was, and we were just a part of IT now. When we add people to our team, many of them have master’s degrees in informatics. Many have done board certifications in informatics, and some have even gone through fellowships. So, we continue to grow, and IT is now part of every part of the health system. I think there’s informatics that is part of our team. Formally, our physician staff includes many informatics representatives. And then our nursing staff now has really kind of come to the table and joined us in this journey. More recently, we brought on a nursing director of informatics, and I continue to see these types of roles growing as time goes on.

Q: So, could you talk to us a little bit about how you, at your community-based health system, how do you think about aligning the digital strategies with your priorities, especially keeping your patients and employees in mind?

Priti: As a community-based health system, our focus is really on our patients, our workforce, and the quality of care that we deliver.

So those are our founding principles, and so when we think about what type of digital tools we would want to implement, we look to see, you know, how does that make them better at what they do? How does it support them? How do we elevate the care with these various tools? We are an epic organization, and so we do have an epic strategy, and that’s true of most of our core applications.

We focus on leveraging what is available to us through our major applications. And then the other key component is really driving the adoption. So, it’s not enough. To really have the application but really trying to leverage it fully is one of the things that my team does is that we identify where perhaps people aren’t really leveraging it in their workflows.

Maybe the patients could really come to know a little bit more about this. So, we have a whole team that goes out to the clinics, to the hospital, and rounds through the floors to really share a lot of that knowledge of what is available through all of our core applications. When we get to a place where our core applications cannot serve the need. Let’s say we have some special strategic initiatives, and you know, ambient AI is a perfect example of this. This is not something that was part of our Epic application. So we looked at other vendors and found one that we thought would be the best fit. This is something that we have integrated with Epic.

However, it is a freestanding application, and we do that with a number of different solutions where we are looking to align it with what we’re the outcome that we have in mind. So, we do add innovation on top of our basic core application structure.

Q: I heard you say before, when we were talking earlier, that you have a Gartner report, which got published around the Ambient Listening initiatives. And that, of course, is a business application, which a lot of health systems are embracing, and they are finding a lot of value in that. But I think you have a lot more to share with the audience on this specific implementation. So, could you talk to us about some of the three aspects I would like to bring out with you, if we can? What were some of the challenges that you faced? What do you think were some of the key success factors, and what were, I think, you measured? Results in this particular case. So, do you have any quantitative results that you could share with the audience? 

Priti: We started our journey very early. This is the technology I was waiting for, as a primary care physician. I really wanted to spend more time with patients instead of interacting with the EHR and spending time on documentation. And so, for a number of years, we were looking at the early ambient solutions that were out there. And then a couple of years ago when large language models came to be. We really focused on that, and so it was early 2003 when we started to look at a variety of different vendors, and we ultimately settled on ambiance, and really, our providers had the opportunity to test it.

We did a lot of role-playing with physicians and complicated patients’ situations, and so we landed on a tool called ambiance. We implemented that very early, in July 2023. I would say that it was a very exciting time, and I think everyone was very interested in utilizing this technology. So, the adoption was easier than most technologies that we’ve tried to implement before because we had that enthusiasm and eagerness from our physician population.

The challenges were that no one had done this before and this was new territory. We were co-developing. A lot of the technology that we have today is things that have evolved over the last year and a half. And so, I think really the exciting part of this was giving people this technology and within four hours, most physicians adopted and start seeing really the benefit of it, really enhancing that human connection.

Finishing their notes on time, being able to go home on time, and not having to spend time, documenting the electronic health record. Patients have also shared with us that they enjoy the interaction that they have with their physicians because now they are face-to-face, and they’re not distracted by any technology.

So, it’s been a really positive experience for us. When we first started, we were in a non-integrated state, so the applications were side by side, and we were copy-pasting notes from the ambiance application into the electronic health record. So, the adoption had slowed because of that lack of integration.

And then once we integrated, all of a sudden, a hundred providers just came out and signed up, and we are ready to go. And you know, at this point, we have 60% of our users utilizing it. And every week our adoption continues to grow, not just with the number of people using it, but just how often they are.

When you look at certain users, some physicians use it a hundred percent of the time. We had one provider that hit the all-time record of 10,000 encounters. So, this is how we deliver care at, John Muir Health. It’s been a really exciting journey. We’ve got lots of qualitative feedback from our physicians, saying that this is something that would allow them to practice for a lot longer.

How it’s given them a light work-life balance backport of the quantitative side. So, we’ve been tracking a number of different outcomes. There are efficiency gains for sure. We’ve seen about 30 minutes of time savings in documentation. And then, when you ask our providers – how much time do you think you’re saving? They will say, we are saving two hours. And so, what that tells you is that they’re feeling less fatigued. There is a tremendous reduction in cognitive load. And so, I think there’s just so many benefits with this technology, and we’re just starting to really realize what it can do. And I foresee this continuing to improve and expand as time goes on.

Q: Yeah, it’s very interesting Priti that you said that the inflection point came when it got integrated with your, in this particular case, Epic system. So that was kind of like a good learning point. So, how did you go about building a data-driven culture? Also, talk to us a little bit about your enterprise data strategy.

Priti: In addition to AI, we have also been focusing a lot on our data strategy. About a year and a half ago, we really focused on a number of different strategic initiatives, and we wanted to really measure outcomes at all levels to be able to drive continuous improvement.

So, we have also implemented lean methodology and a daily continuous performance improvement program that everyone is doing at all levels of the organization, from leadership to the frontline. So, there was this incredible need for data to see how we are driving our operational success. And so that really laid that sort of foundational need for data.

One of the things that my team did was really try to figure out how we can support each of the users in their need for data. So, about a year ago, we launched a data literacy program. We have lots of dashboards, lots of reports, and self-serving tools but unfortunately, people don’t know how to use these tools; they’re not able to access the data that they need.

So we, starting with our C-Suite, did one-to-one training with on a variety of different reporting and analytics tools. From there, we moved to the directors and the managers. We have webinars, recorded self-service, and self-paced learning. We have open office hours now so that people can drop in.

What’s astounding is that you see the increase in the reporting tool usage, and then when we are doing our weekly report outs on all of the variety of the various strategic initiatives, everyone is now speaking with data and really sharing their outcomes and tracking that. So, it has been a really exciting journey where, a number of different initiatives came together.

And then the State of Literacy program was there to support everyone’s need for data to support, the work that they have been doing.

Q: I am sure in this journey, when you try to do cultural changes there is always change management, which comes into play, and then I’m sure you are adept at balancing your innovation efforts with the clinician or the patient design. So, talk to us a little bit about how do you drive innovation, change management, and what are some of the things that you are seeing are working or not working in that space?

Priti: Yeah, change management is by far the most important component. When I think about what I do every day, even as a position, I was a change management agent.

And then on the IT and informatics side that skill comes in very handy. Even if you have the best technology, the technology that you think is really going to support the clinician or the business owner, I think what happens is not everyone approaches that technology the same way, and they need support in different ways.

They need to understand why they should use it and how it will help them. That is one of the things that we do as informaticists is we really try to bridge the workflow with technology. If technology is designed well, it is very easy to do. If it is not really designed with the end user in mind, then that’s where, the change management becomes even more challenging.

So, I think that change management is really key to adoption. Adoption is really key to seeing the benefits of technology so that connection is really key.

Q: As we move on to more discussions around AI and GenAI, what are you thinking could be the next initiatives? You have a very successful one already underway, and things are changing fast around us. As you know, everyone is talking about Gen AI. In fact, we have a webinar coming up in the next two weeks on Agentic AI, and I was surprised by the number of registrations for that. It seems to be very topical and of great interest. So, how are you thinking about new AI initiatives and Gen AI in your organization?

And I know you might be early on how you are thinking about the policies and the governance aspects as well.

Priti: Yeah, this is a very exciting time, and we, too, are excited about the AI agents where we have started with GenAI. I mean, our first application was the ambient scribe. But we have also been utilizing Gen AI to help draft responses back to messages that come from patients.

So, it really helps reduce the documentation burden. We are thinking about leveraging it on the inpatient side for nurses to help create care plans. In about a month, we are going to start a pilot to really look at how GenAI can and natural language processing can really summarize the medical record.

So, our inpatient physicians have to spend a lot of time looking through the chart to really understand why the patient might be in the hospital. And so, there are some great tools that might help summarize and really raise up some very pertinent points to care that’s a pilot that we’re really excited about.

There are a number of different applications on the business side, so when you think about doing prior authorization and letters for responses to denials. Those are really appealing use cases where I think a lot of people spend time in this paperwork, administrative back and forth.

And this is where gen AI really has a great application.  As I mentioned, we’re on this data-driven journey and teaching people how to leverage these self-service tools. There is quite the learning curve, you know, on how to sort of set up your query, right? And that’s where natural language processing and gen AI may be very helpful.

So, there are some tools that we’ve been looking at to say, can the user just speak out their query. So that then the data analysis is done for them and then they can more easily utilize it. So that is really exciting. We have been doing a lot in predictive analytics, so that’s kind of the next level. I mean, having the data and the EHR is one thing, but now, doing things with it, that is where the magic really happens. So, we have a number of different predictive analytics tools live today. One that helps predict readmissions. We have another one that has been in play for a very long time, really predicting the high-risk patients, those who are at risk for clinical deterioration in the hospital.

So, that’s been great at identifying those who may be developing sepsis or may need a higher level of care. We have a great tool that helps us detect steps stroke early and really mobilize the team. And that has really improved our stroke care. So, I think there’s so many applications and tools.

It is almost like we have so many solutions that how do we implement these fast enough in order to, You know, really take advantage of everything that is out there. And then, of course agentic AI is coming, and that is something that we’re very excited about, too. So, I’ve had a chance to see a few demos, and it was very compelling. So yeah, we’ll have to see what happens over the next six months.

Q: That’s amazing. So, I think as we are heading to the close of the podcast, Priti, are there any other thoughts or information you would like to share with the audience before we close?

Priti: Yeah, this is a very exciting time to be part of this. I think we’ve all kind of noticed that there’s something different in the last year. And I would say that I am really interested in everything that’s out there and trying to find a solution that will fit our problems. That is always a challenge and when I think about what would really make a big difference for us is finding solutions that really solve problems that we have. I am someone who really enjoys technology, and so everything’s exciting, but how do you figure out what’s the one that’s really going to make a big difference and really improve patient care and experience for our clinicians? 

Subscribe to our podcast series at www.thebigunlock.com and write us at [email protected] 

Disclaimer: This Q&A has been derived from the podcast transcript and has been edited for readability and clarity.




About the host

Paddy is the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor & Francis, Aug 2020), along with Edward W. Marx. Paddy is also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He is the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He is widely published and has a by-lined column in CIO Magazine and other respected industry publications.

About the Host

Ritu M. Uberoy has over twenty-five years of experience in the software and information technology industry in the United States and in India. She established Saviance Technologies in India and has been involved in the delivery of several successful software projects and products to clients in various industry segments.

Ritu completed AI for Health Care: Concepts and Applications from the Harvard T.H. Chan School of Public Health and Applied Generative AI for Digital Transformation from MIT Professional Education. She has successfully taught Gen AI concepts in a classroom setting in Houston and in workshop settings to C-Suite leaders in Boston and Cleveland. She attended HIMSS in March 2024 at Orlando and the Imagination in Action AI Summit at MIT in April 2024. She is also responsible for the GenAI Center of Excellence at BigRio and DigiMTM Digital Maturity Model and Assessment at Damo.

Ritu earned her Bachelor’s degree in Computer Science from Delhi Institute of Technology (now NSIT) and a Master’s degree in Computer Science from Santa Clara University in California. She has participated in the Fellow’s program at The Wharton School, University of Pennsylvania.

About the Host

Rohit Mahajan is an entrepreneur and a leader in the information technology and software industry. His focus lies in the field of artificial intelligence and digital transformation. He has also written a book on Quantum Care, A Deep Dive into AI for Health Delivery and Research that has been published and has been trending #1 in several categories on Amazon.

Rohit is skilled in business and IT  strategy, M&A, Sales & Marketing and Global Delivery. He holds a bachelor’s degree in Electronics and Communications Engineering, is a  Wharton School Fellow and a graduate from the Harvard Business School. 

Rohit is the CEO of Damo, Managing Partner and CEO of BigRio, the President at Citadel Discovery, Advisor at CarTwin, Managing Partner at C2R Tech, and Founder at BetterLungs. He has previously also worked with IBM and Wipro. He completed his executive education programs in AI in Business and Healthcare from MIT Sloan, MIT CSAIL and Harvard School of Public Health. He has completed  the Global Healthcare Leaders Program from Harvard Medical School.

About the Legend

Paddy was the co-author of Healthcare Digital Transformation – How Consumerism, Technology and Pandemic are Accelerating the Future (Taylor &  Francis, Aug 2020), along with Edward W. Marx. Paddy was also the author of the best-selling book The Big Unlock – Harnessing Data and Growing Digital Health Businesses in a Value-based Care Era (Archway Publishing, 2017). He was the host of the highly subscribed The Big Unlock podcast on digital transformation in healthcare featuring C-level executives from the healthcare and technology sectors. He was widely published and had a by-lined column in CIO Magazine and other respected industry publications.

The Healthcare Digital Transformation Leader

Stay informed on the latest in digital health innovation and digital transformation.

The Healthcare Digital Transformation Leader

Stay informed on the latest in digital health innovation and digital transformation

The Healthcare Digital Transformation Leader

Stay informed on the latest in digital health innovation and digital transformation.